Yamasaki Ryou 山崎亮

… Alternative Names

Yamasaki Ryo 山崎亮

山崎亮ヤマサキリヨウ

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Researcher Number	10467946
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2025: 九州大学, 医学研究院, 准教授 2015: 九州大学, 大学病院, 講師 2015: 九州大学病院, 講師 2013 – 2014: 九州大学, 医学(系)研究科(研究院), 助教 2009 – 2010: Kyushu University, 大学病院, 助教
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 52020:Neurology-related / Neurology / Medium-sized Section 52:General internal medicine and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52030:Psychiatry-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General internal medicine and related fields / Radiation science / Biological Sciences
Keywords	Principal Investigator マクロファージ / 筋萎縮性側索硬化症 / 実験的自己免疫性脳脊髄炎 / アストログリア / 多発性硬化症 / ミクログリア / 末梢神経障害 / SOD1 / ケモカイン / 変異SOD1トランスジェニックマウス … More / ミスフォールド蛋白 / 筋萎縮性側索効果症 / CCR2 / 変異SOD1 / モデルマウス / 異常蛋白 / 末梢神経 / マウスモデル / 動物モデル / オリゴデンドログリア / コネキシン / 単球 / エンドセリン / EDNRB / 変異SOD1遺伝子導入マウス / G-CSF / ALS … More Except Principal Investigator 多発性硬化症 / ミクログリア / コネキシン / 筋萎縮性側索硬化症 / 多系統萎縮症 / 脱髄 / バイオマーカー / オリゴデンドロサイト / アストロサイト / アストログリア / ギャップ結合 / シヌクレイン / 脱髄疾患 / グリア性炎症 / αシヌクレイン / グリア炎症 / オリゴデンドログリア / グリアシンシチウム / 視神経脊髄炎 / マクロファージ / グリア細胞 / パルブアルブミン / カルビンディン / カルレチニン / 重症化 / エクソソーム / α-シヌクレイン / 神経炎症 / 神経内科疾患 / 神経障害性疼痛 / 自己抗体 / 神経免疫疾患 / 診断マーカー / 脳脊髄液 / 環境因子 / マウスモデル / 動物モデル / マイクロRNA / エキソソーム / 遺伝子 / galectin-3 / 末梢神経 / モデルマウス / アルツハイマー病 / エネルギー供給障害 / グリアアセンブリ / 神経科学 / GWAS / グリア / 実験的自己免疫性脳脊髄炎 / 病理 / 中枢神経自己免疫疾患 / 免疫治療 / 神経内科 / 精神科 / トランスレーショナル研究 / 精神神経疾患 / RNA velocity / scRNA-seq / NK細胞 / 努力肺活量 / 進行速度 / 病態解明 / mRNA品質管理機構 / 重症化因子 / 視神経脊髄炎スペクトラム障害 / 中枢神経系自己免疫性疾患 / ALFoC / グリア性炎症惹起性 / CCL2 / MCP1 / 培養ミクログリア / カルシウム結合蛋白 / 培養実験 / グリア由来エキソソーム / イソフォーム / グリア線維性蛋白 / 二次進行型 / 進行型多発性硬化症 / 小脳型多系統萎縮症 / グリア標的治療 / グリオパチー / α―シヌクレイン / 小脳失調 / αーシヌクレイン / 神経変性疾患 / 遺伝環境リスク / 抗核抗体 / PlexinD1 / NF155 / 慢性炎症性脱髄性多発神経根炎 / ノド抗体 / アトピー性脊髄炎 / アトピー / 自己免疫 / 慢性炎症性脱髄性多発神経炎 / 炎症 / galectin3 / p22 / ガレクチン3 / ELISA / 血液脳関門 / 髄鞘淡明化 / 脊髄前・側索 / 腸内細菌叢 / 米 / 食事 / 免疫細胞 / 疾患修飾薬 / 免疫細胞解析 / 喫煙 / コメ摂取 / 一次性進行型多発性硬化症 / α-synuclein / α- シヌクレイン / 一次進行型多発性硬化症 / トランスジェニックマウス / CSF1R阻害薬 / intermediate monocytes / TGFbeta / イルベサルタン / 肥厚性硬膜炎 / MR neurography / 核磁気共鳴画像 / MRI / 慢性炎症性脱髄性多発根神経炎 / 磁気共鳴画像 / 慢性炎症性脱髄性多発根神経炎患者 / タウ蛋白 / 病的タウ / 毒性アミロイドベータ / CD33 / リン酸化タウタンパク / アミロイドβタンパク / 脳神経疾患 / TDP-43 / 運動ニューロン変性 / 活性化ミクログリア / macrophage / microglia / osteopontin / p22phox / 脊髄前側索 / T細胞 / 免疫グリア細胞間相互作用 / 一卵性双生児 / 病原性T細胞 / 病原性Th17細胞 / Th17細胞 / レトロエレメント / M2 / CCR2 / 変異SOD1トランスジェニックマウス / 自然免疫 / γδT細胞 / 栄養トランスポーター / 栄養供給障害 / インスリン分泌能 / インスリン抵抗性 / 記憶機能 / インスリン受容体基質 / インスリン分解酵素 / 記憶障害 / 3xTg-ADマウス / リン酸化タウ蛋白 / 毒性ターン / アミロイドβ蛋白 / アポモルフィン / 糖尿病 / 脱髄性疾患 / アクアポリン4 / Balo病 / ゲノム解析 / 感覚過敏症 / 統合失調症 / 精神疾患 / 神経病理 / EAE / SOD1 Less

Estimation of Underlying Pathologies and Pursuit of Personalized Treatments for Central Nervous System Autoimmune Diseases Using Biomarkers
- Principal Investigator
  
  渡邉充
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyushu University
Deciphering the pathogenesis and detection of therapeutic targets for ALS depending on diffuse myelin pallor in anterolateral funiculi outside the corticospinal tracts of spinal cord..
- Principal Investigator
  
  林信太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Elucidation of inflammation regulatory mechanisms in central nervous system autoimmune diseases
- Principal Investigator
  
  磯部紀子
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Elucidation of the pathogenesis and identification of novel therapeutic targets using a new scale assessing the clinical diversity of ALS
- Principal Investigator
  
  小早川優子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
コネキシン43結合性マイクロRNAを介する多発性硬化症重症化機構の解明と治療開発
- Principal Investigator
  
  中村優理
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  International University of Health and Welfare
RNA 動的解析による固形腫瘍を破壊可能なGAIA-102の分化誘導機構の解明
- Principal Investigator
  
  米満吉和
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyushu University
免疫学的視点からみた中枢性神経障害性疼痛の病態解明ならびに新規治療法開発
- Principal Investigator
  
  藤井敬之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
ヘミチャネル阻害薬を用いたαシヌクレイン伝播阻止による多系統萎縮症の治療法開発
- Principal Investigator
  
  真崎勝久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Detection of ALS origin with reference to calcium-binding proteins, those generate glial inflammation
- Principal Investigator
  
  林信太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
単一細胞RNA解析による多系統萎縮症増悪性ミクログリア亜群の同定と同細胞標的療法
- Principal Investigator
  
  山口浩雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
What is microglial activation in neuropsychiatric disorders? A cross-disease study using human cells.
- Principal Investigator
  
  扇谷昌宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Asahikawa Medical College
Exacerbation of demyelination by glia connexin truncated isoform-expressing exosomes and its therapy development
- Principal Investigator
  
  Nakamura Yuri
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  International University of Health and Welfare
Novel therapy for progressive multiple sclerosis and multiple system atrophy by glial regulation
- Principal Investigator
  
  Katsuhisa Masaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Misfold protein removal therapy with CCR2-positive cells from peripheral nerves in motor neuron diseasePrincipal Investigator
- Principal Investigator
  
  Yamasaki Ryo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Establishment of primary-progressive multiple sclerosis (PPMS)/multiple system atrophy (MSA) mice model
- Principal Investigator
  
  Yamaguchi Hiroo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Development of treatment for multiple sclerosis based on rice consumption, a newly identified environmental risk factor
- Principal Investigator
  
  Watanabe Mitsuru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Significance of and treatment against galectin-3 and p22 accompanied with glial inflamation in ALS spinal cord
- Principal Investigator
  
  HAYASHI SHINTARO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Elucidation of autoimmune mechanisms and developement of novel therapy for demyelinating diseases based on genetic and envrionmental risk factors and disease-specific anti-neural antibodies
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  International University of Health and Welfare
  Kyushu University
A novel model of multiple sclerosis and multiple system atrophy that are differentially manifested by the time of abnormal protein expression
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  International University of Health and Welfare
  Kyushu University
A novel mice model of MSA by overexpression of mutant alpha-synuclein in oligodendroglia in a temporarily restrictive manner using Tet-off system
- Principal Investigator
  
  Matsuse Dai
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyushu University
Elucidation of the role of glial cell in tau transmission and axonal degeneration in Alzheimer's disease and targeted therapy with glial cell
- Principal Investigator
  
  Asai Hirohide
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Development of new MR neurography with simultaneous T2 mapping
- Principal Investigator
  
  Hiwatashi Akio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
Establishment of world-premier pachymeningitis animal model and development of new therapeutic option targeting TGF-beta.
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Kyushu University
Elucidation of mechanisms for destruction and fixation of glia-syncytium in demyelinating diseases by whole-genome sequencing and immunohistochemical analysis.
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Development of new therapeutic options for multiple sclerosis by suppression of CNS immune system augmentation due to the malfunction of astroglia connexinPrincipal Investigator
- Principal Investigator
  
  Yamasaki Ryo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
The origin of retrograde motor neuron degeneration elicited by activated microglia in pre- or early-symptomatic spinal cord tissues from human patients with amyotrophic lateral sclerosis
- Principal Investigator
  
  Hayashi Shintaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Therapy for multiple sclerosis targeting gamma-delta T cells and innate immunity based on genome-wide association studies in Japanese population
- Principal Investigator
  
  Matsushita Takuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Elucidation of pathomecanisms via CCR2 positive monocyte-dependent neuroprotection in the amyotrophic lateral sclerosis model mice.
- Principal Investigator
  
  Tateishi Takahisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Retro-element insertion polymorphism in pathogenic Th17 cells specific for multiple sclerosis and its action
- Principal Investigator
  
  Yuji Kawano
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Development of apomorphine therapy targeting insulin resistance in Alzheimer's disease
- Principal Investigator
  
  Ohyagi Yasumasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Ehime University
  Kyushu University
Extensive disruption of energy transports via glial syncytium in demyelinating diseases
- Principal Investigator
  
  Masaki Katsuhisa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Elucidasion of functional contribution of glial dysturbances in pathomechanisms of demyelinating diseases and schizophrenia and development of new therapeutic options
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
connexin cytopathy in the pathogenesis of demyelinating disorders
- Principal Investigator
  
  Kira Jun-ichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Complete remission induction therapy development of multiple sclerosis by selective - timed activation of the protective microgliaPrincipal Investigator
- Principal Investigator
  
  Yamasaki Ryo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
ALSに対するG-CSFの運動ニューロン保護作用の解明と髄腔内持続投与療法の開発Principal Investigator
- Principal Investigator
  
  山崎亮
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2009 Other

All Journal Article Presentation

[Journal Article] Distinct effects among calcium-binding proteins for microglia to produce chemokines associated with the clinical severity of ALS.2023
- Author(s)
  Hayashi S, Yamasaki R, Kira JI, Isobe N.
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 14 Issue: 1 Pages: 69-73
- DOI
  10.1111/cen3.12738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07517
[Journal Article] Effect of smoking on disease activity in multiple sclerosis patients treated with dimethyl fumarate or fingolimod2023
- Author(s)
  Tanaka E, Watanabe M, Fukumoto S, Masaki K, Yamasaki R, Matsushita T, Isobe N
- Journal Title
  
  Mult Scler Relat Disord
  
  Volume: - Pages: 104513-104513
- DOI
  10.1016/j.msard.2023.104513
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07464, KAKENHI-PROJECT-22K07351, KAKENHI-PROJECT-20K07889, KAKENHI-PROJECT-23K06965
[Journal Article] Anti-LGI4 antibody is a novel juxtaparanodal autoantibody for chronic inflammatory demyelinating polyneuropathy2023
- Author(s)
  Zhang X, Kira J, Ogata H, Imamura T, Mitsuishi M, Fujii T, Kobayashi M, Kitagawa K, Namihira Y, Ohya Y, Maimaitijiang G, Yamasaki R, Fukata Y, Fukata M, Isobe N, Nakamura Y.
- Journal Title
  
  Neurology Neuroimmunology and Neuroinflammation
  
  Volume: 10(2) Issue: 2 Pages: 1-13
- DOI
  10.1212/nxi.0000000000200081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07467, KAKENHI-PROJECT-21K19390, KAKENHI-PROJECT-22K15717, KAKENHI-PROJECT-20H00459, KAKENHI-PROJECT-20K16602, KAKENHI-PROJECT-21K15700, KAKENHI-PROJECT-21K15703, KAKENHI-PROJECT-20K22910, KAKENHI-PROJECT-23K23986, KAKENHI-PROJECT-23K18266, KAKENHI-PROJECT-22K07499
[Journal Article] Iguratimod Ameliorates the Severity of Secondary Progressive Multiple Sclerosis in Model Mice by Directly Inhibiting IL-6 Production and Th17 Cell Migration via Mitigation of Glial Inflammation2023
- Author(s)
  Nagata Satoshi、Yamasaki Ryo、Takase Ezgi Ozdemir、Iida Kotaro、Watanabe Mitsuru、Masaki Katsuhisa、Wijering Marion Heleen Cath?rine、Yamaguchi Hiroo、Kira Jun-ichi、Isobe Noriko
- Journal Title
  
  Biology
  
  Volume: 12 Issue: 9 Pages: 1217-1217
- DOI
  10.3390/biology12091217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18266, KAKENHI-PROJECT-22K07540, KAKENHI-PROJECT-23K06965
[Journal Article] Calretinin activates microglia to produce CC-motif ligand 2 relevant to clinical severity of ALS2023
- Author(s)
  Hayashi S, Yamasaki R, Kobayakawa Y, et al.
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 24 Issue: sup1 Pages: 115-127
- DOI
  10.1080/21678421.2023.2260193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07517
[Journal Article] High-dose ubiquinol supplementation in multiple-system atrophy : a multicentre, randomised, double-blinded, placebo-controlled phase 2 trial2023
- Author(s)
  Mitsui J, Matsukawa T, Uemura Y, Kawahara T, Matsuse D, Yamasaki R, Kira J, Tsuji S, et al.
- Journal Title
  
  eClinicalMedicine
  
  Volume: 101920 Pages: 1-13
- DOI
  10.1016/j.eclinm.2023.101920
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-23K18266
[Journal Article] The first evaluation of calretinin in the spinal axons encompassed in anterolateral funiculi outside the cortical tract and cerebrospinal fluids of ALS patients.2022
- Author(s)
  Hayashi S, Yamasaki R, Kobayakawa Y, Kira JI, Isobe N.
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 23 Issue: sup1 Pages: 101-102
- DOI
  10.1080/21678421.2022.2120682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07517
[Journal Article] Axonal protein, calretinin, stimulates microglia to produce chemokines associated with clinical severity of ALS2022
- Author(s)
  Shintaro Hayashi, Ryo Yamasaki, Jun-ichi Kira
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07996
[Journal Article] Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy2022
- Author(s)
  Yuji Nishimura, Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Tatsunori Tanaka1, Eriko Matsuo, Shotaro Hayashida, Mitsuru Watanabe, Takuya Matsushita, Shoko Sadashima, Naokazu Sasagasako, Ryo Yamasaki, Noriko Isobe, Toru Iwaki, Jun-ichi Kira
- Journal Title
  
  Brain Pathology
  
  Volume: - Issue: 3 Pages: 1-16
- DOI
  10.1111/bpa.13131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07438, KAKENHI-PROJECT-22K07540, KAKENHI-PROJECT-20K07889, KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-21K20873, KAKENHI-PROJECT-23K18266, KAKENHI-PROJECT-23K19567, KAKENHI-PROJECT-23K06965
[Journal Article] Teaching Video NeuroImage: Reversible Parkinsonism Caused by Lumboperitoneal Shunt Overdrainage.2022
- Author(s)
  Takeuchi H, Masaki K, Ogata H, Nagata S, Shimogawa T, Yamasaki R, Isobe N.
- Journal Title
  
  Neurology.
  
  Volume: 99 Issue: 11 Pages: 486-488
- DOI
  10.1212/wnl.0000000000200994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07889
[Journal Article] Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation2022
- Author(s)
  Yu Hashimoto, Ryo Yamasaki, Senri Ko, Eriko Matsuo, Yuko Kobayakawa, Katsuhisa Masaki, Dai Matsuse, Noriko Isobe
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 24 Pages: 16046-16046
- DOI
  10.3390/ijms232416046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07438, KAKENHI-PROJECT-20K07889
[Journal Article] Calcium-binding proteins stimulate microglia to induce pro-inflammatory mediators similar to ALS2021
- Author(s)
  Hayashi S, Yamasaki R, Kira J.
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07996
[Journal Article] Early postnatal allergic airway 1 inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior.2021
- Author(s)
  Saitoh BY, Tanaka E, Yamamoto N, Kruininge DV, Iinuma K, Nakamuta Y, Yamaguchi H, Yamasaki R, Matsumoto K, Kira J:
- Journal Title
  
  Brain Behavior and Immunity
  
  Volume: 95 Pages: 362-380
- DOI
  10.1016/j.bbi.2021.04.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Journal Article] Serum anti-oligodendrocyte autoantibodies in patients with multiple sclerosis detected by a tissue-based immunofluorescence assay2021
- Author(s)
  Miyachi Y, Fujii T, Yamasaki R, Tsuchimoto D, Iinuma K, Sakoda A, Fukumoto S, Matsushita T, Masaki K, Isobe N, Nakabeppu Y, Kira J.
- Journal Title
  
  Front Neurol
  
  Volume: 12 Pages: 681980-681980
- DOI
  10.3389/fneur.2021.681980
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K07889, KAKENHI-PROJECT-21K07464, KAKENHI-PROJECT-21K15700
[Journal Article] Clearance of peripheral nerve misfolded mutant protein by infiltrated macrophages correlates with motor neuron disease progression2021
- Author(s)
  白石渉、山﨑亮、橋本侑、江千里、小早川優子、磯部紀子、松下拓也、吉良潤一
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16438-16438
- DOI
  10.1038/s41598-021-96064-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07963, KAKENHI-PROJECT-19K17010
[Journal Article] Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination.2021
- Author(s)
  Une H, Yamasaki R, Nagata S, Yamaguchi H, Nakamuta Y, Indiasari UC, Cui YW, Shinoda K, Masaki K, Gotz M, Kira J:
- Journal Title
  
  J Neuroinflammation
  
  Volume: 18 Issue: 1 Pages: 126-126
- DOI
  10.1186/s12974-021-02176-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K07889, KAKENHI-PROJECT-20K20470
[Journal Article] Anti-Plexin D1 antibodies relate to small fiber neuropathy and induce neuropathic pain in animals.2021
- Author(s)
  Fujii T, Lee E-J, Miyachi Y, Yamasaki R, Lim Y-M, Iinuma K, Sakoda A, Kim K-K, Kira J:
- Journal Title
  
  Neurology: Neuroimmunology & Neuroinflammation
  
  Volume: 8(5) Issue: 5
- DOI
  10.1212/nxi.0000000000001028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-21K15700
[Journal Article] Early decrease in intermediate monocytes in peripheral blood is characteristic of multiple system atrophy-cerebellar type2020
- Author(s)
  Dai Matsuse, Ryo Yamasaki, Guzailiayi Maimaitijiang, Hiroo Yamaguchi, Katsuhisa Masaki, Noriko Isobe, Takuya Matsushita, Jun-ichi Kira
- Journal Title
  
  Journal of Neuroimmunology
  
  Volume: 349 Pages: 577395-577395
- DOI
  10.1016/j.jneuroim.2020.577395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07501, KAKENHI-PROJECT-20K07889
[Journal Article] Environmental risk factors for multiple sclerosis in Japanese people2020
- Author(s)
  Sakoda A, Matsushita T, Nakamura Y, Watanabe M, Shinoda K, Masaki K, Isobe N, Yamasaki R, Kira J.
- Journal Title
  
  Multiple Sclerosis and Related Disorders
  
  Volume: 38 Pages: 101872-101872
- DOI
  10.1016/j.msard.2019.101872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07529, KAKENHI-PROJECT-19K07995, KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-20K07889
[Journal Article] Calcium-binding proteins stimulate microglia to induce pro-inflammatory mediators relevant to ALS2020
- Author(s)
  Hayashi S, Yamasaki R, Okamoto K, KIra J.
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07996
[Journal Article] Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibody serostatus along with fingolimod2020
- Author(s)
  Watanabe Mitsuru、Nakamura Yuri、Isobe Noriko、Tanaka Masami、Sakoda Ayako、Hayashi Fumie、Kawano Yuji、Yamasaki Ryo、Matsushita Takuya、Kira Jun-ichi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 17 Issue: 1 Pages: 206-206
- DOI
  10.1186/s12974-020-01865-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07997, KAKENHI-PROJECT-19H01045
[Journal Article] Central nervous system-specific antinuclear antibodies in patients with multiple sclerosis2020
- Author(s)
  Fujii T, Yamasaki R, Miyachi Y, Nagata S, Maimaitijiang G, Nakamura Y, Shinoda K, Matsushita T, Isobe N, Kira J.
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 409 Pages: 116619-116619
- DOI
  10.1016/j.jns.2019.116619
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07529, KAKENHI-PROJECT-19K17037, KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K20470
[Journal Article] Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis2020
- Author(s)
  Zhao Y, Yamasaki R, Yamaguchi H, Nagata S, Une H, Cui Y, Masaki K, Nakamuta Y, Iinuma K, Watanabe M, Matsushita T, Isobe N, Kira J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 4 Pages: 2160-2169
- DOI
  10.1073/pnas.1901294117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07529, KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-20K07889, KAKENHI-PROJECT-19H01045
[Journal Article] A case of overlapping adult-onset linear scleroderma and Parry-Romberg syndrome presenting with widespread ipsilateral neurogenic involvement2020
- Author(s)
  Yamasaki R, et al.
- Journal Title
  
  Neuropathology
  
  Volume: 40 Issue: 1 Pages: 109-115
- DOI
  10.1111/neup.12614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20470
[Journal Article] Painful trigeminal neuropathy associated with anti-Plexin D1 antibody2020
- Author(s)
  Fujii Takayuki、Yamasaki Ryo、Miyachi Yukino、Iinuma Kyoko、Hashimoto Yu、Isobe Noriko、Matsushita Takuya、Kira Jun-ichi
- Journal Title
  
  Neurology - Neuroimmunology Neuroinflammation
  
  Volume: 7 Issue: 5
- DOI
  10.1212/nxi.0000000000000819
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17037, KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-18K07529
[Journal Article] Unique HLA haplotype associations in IgG4 anti-neurofascin 155 antibody-positive chronic inflammatory demyelinating polyneuropathy2020
- Author(s)
  Ogata H, Isobe N, Zhang X, Yamasaki R, Fujii T, Machida A, Morimoto N, Kaida K, Masuda T, Ando Y, Kuwahara M, Kusunoki S, Nakamura Y, Matsushita T, Kira J.
- Journal Title
  
  Journal of Neuroimmunology
  
  Volume: 339 Pages: 577139-577139
- DOI
  10.1016/j.jneuroim.2019.577139
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07529, KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-18K15454, KAKENHI-PROJECT-18K15455
[Journal Article] Risk HLA-DRB1 alleles differentially influence brain and lesion volumes in Japanese patients with multiple sclerosis2020
- Author(s)
  Fukumoto S, Nakamura Y, Watanabe M, Isobe N, Matsushita T, Sakoda A, Hiwatashi A, Shinoda K, Yamasaki R, Tsujino A, Kira J.
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 413 Pages: 116768-116768
- DOI
  10.1016/j.jns.2020.116768
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07529, KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-19K21317
[Journal Article] Insulin deficiency promotes formation of toxic amyloid-beta42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.2020
- Author(s)
  Imamura T, Yanagihara YT, Ohyagi Y, Nakamura N, Iinuma KM, Yamasaki R, Asai H, Maeda M, Murakami K, Ilie K, Kira JI
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 137 Pages: 104739-104739
- DOI
  10.1016/j.nbd.2020.104739
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09302, KAKENHI-PROJECT-17K09757, KAKENHI-PROJECT-20K07826
[Journal Article] Distinct microglial and macrophage distribution patterns in the concentric and lamellar lesions in Bal?'s disease and neuromyelitis optica spectrum disorders2020
- Author(s)
  Hayashida Shotaro、Masaki Katsuhisa、Suzuki Satoshi O.、Yamasaki Ryo、Watanabe Mitsuru、Koyama Sachiko、Isobe Noriko、Matsushita Takuya、Takahashi Kazuya、Tabira Takeshi、Iwaki Toru、Kira Jun‐ichi
- Journal Title
  
  Brain Pathology
  
  Volume: 30 Issue: 6 Pages: 1144-1157
- DOI
  10.1111/bpa.12898
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07889, KAKENHI-PROJECT-19H01045
[Journal Article] Novel Neuropathic Pain Mechanisms Associated With Allergic Inflammation2019
- Author(s)
  Fujii Takayuki、Yamasaki Ryo、Kira Jun-ichi
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 10 Pages: 1-8
- DOI
  10.3389/fneur.2019.01337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17037, KAKENHI-PROJECT-19H01045
[Journal Article] Simultaneous MR neurography and apparent T2 mapping in brachial plexus: Evaluation of patients with chronic inflammatory demyelinating polyradiculoneuropathy.2019
- Author(s)
  Hiwatashi A, Togao O, Yamashita K, Kikuchi K, Momosaka D, Nakatake H, Yamasaki R, Ogata H, Yoneyama M, Kira JI, Honda H.
- Journal Title
  
  Magn Reson Imaging
  
  Volume: 55 Pages: 112-117
- DOI
  10.1016/j.mri.2018.09.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10408, KAKENHI-PROJECT-18K15454
[Journal Article] Intrathecal cytokine profile in neuropathy with anti‐neurofascin 155 antibody2019
- Author(s)
  Ogata H, Zhang X, Yamasaki R, Fujii T, Machida A, Morimoto N, Kaida K, Masuda T, Ando Y, Kuwahara M, Kusunoki S, Nakamura Y, Matsushita T, Isobe N, Kira J.
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 6 Issue: 11 Pages: 2304-2316
- DOI
  10.1002/acn3.50931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07529, KAKENHI-PROJECT-19H01045, KAKENHI-PROJECT-20K20470, KAKENHI-PROJECT-18K15454, KAKENHI-PROJECT-18K15455
[Journal Article] Microglial galectin-3 in the spinal white matter is a key molecule for motor neuron degeneration in ALS2019
- Author(s)
  Hayashi S, Yamasaki R, Kira JI, et al.
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 20 Issue: sup1 Pages: 74-75
- DOI
  10.1080/21678421.2019.1646546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07996
[Journal Article] Pathological study of glial inflammation in clinically pre-symptomatic spinal cords in patients with sporadic amyotrophic lateral sclerosis2018
- Author(s)
  Hayashi S, Yamasaki R, Kira JI, et al.
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 19 Pages: 48-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09721
[Journal Article] Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model.2018
- Author(s)
  Fujita A, Yamaguchi H, Yamasaki R, Cui Y, Matsuoka Y, Yamada KI, Kira JI.
- Journal Title
  
  J Neuroinflammation.
  
  Volume: 15 Issue: 1 Pages: 227-227
- DOI
  10.1186/s12974-018-1251-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14884, KAKENHI-PROJECT-16H02657, KAKENHI-PROJECT-16K09694, KAKENHI-PROJECT-17K19663
[Journal Article] Association of Decreased Percentage of Vδ2+Vγ9+ γδ T Cells With Disease Severity in Multiple Sclerosis2018
- Author(s)
  Maimaitijiang G, Shinoda K, Nakamura Y, Masaki K, Matsushita T, Isobe N, Yamasaki R, Yoshikai Y, Kira J.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 1-10
- DOI
  10.3389/fimmu.2018.00748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06938, KAKENHI-PROJECT-15K09341, KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-16H02657, KAKENHI-PROJECT-17K19663
[Journal Article] Parallel fluctuation of anti-neurofascin 155 antibody levels with clinico-electrophysiological findings in patients with chronic inflammatory demyelinating polyradiculoneuropathy2018
- Author(s)
  Fujita Atsushi、Ogata Hidenori、Yamasaki Ryo、Matsushita Takuya、Kira Jun-ichi
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 384 Pages: 107-112
- DOI
  10.1016/j.jns.2017.11.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07051, KAKENHI-PROJECT-15K09343, KAKENHI-PROJECT-17K19663
[Journal Article] Lumbar plexus in patients with chronic inflammatory demyelinating polyradiculoneuropathy: evaluation with simultaneous T2 mapping and neurography method with SHINKEI.2018
- Author(s)
  Hiwatashi A, Togao O, Yamashita K, Kikuchi K, Momosaka D, Nakatake H, Yamasaki R, Ogata H, Yoneyama M, Kira JI, Honda H.
- Journal Title
  
  Br J Radiol
  
  Volume: 91 Issue: 1092 Pages: 20180501-20180501
- DOI
  10.1259/bjr.20180501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10408, KAKENHI-PROJECT-18K15454
[Journal Article] Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia2018
- Author(s)
  Fang Mei、Yamasaki Ryo、Li Guangrui、Masaki Katsuhisa、Yamaguchi Hiroo、Fujita Atsushi、Isobe Noriko、Kira Jun-ichi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 2588-2588
- DOI
  10.3389/fimmu.2018.02588
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02657, KAKENHI-PROJECT-16K09694, KAKENHI-PROJECT-17K19663
[Journal Article] Novel disease-modifying anti-rheumatic drug iguratimod suppresses chronic experimental autoimmune encephalomyelitis by down-regulating activation of macrophages/microglia through an NF-κB pathway2018
- Author(s)
  Guangrui Li, Ryo Yamasaki, Mei Fang, Katsuhisa Masaki, Hirofumi Ochi, Takuya Matsushita, Jun-ichi Kira
- Journal Title
  
  SCIENTIFIC REPORTS
  
  Volume: 8 Issue: 1 Pages: 1933-1933
- DOI
  10.1038/s41598-018-20390-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09694, KAKENHI-ORGANIZER-25117001, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-15K09343, KAKENHI-PROJECT-16H02657, KAKENHI-PROJECT-17K19663
[Journal Article] Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis2018
- Author(s)
  Kobayakawa Yuko、Masaki Katsuhisa、Yamasaki Ryo、Shiraishi Wataru、Hayashida Shotaro、Hayashi Shintaro、Okamoto Koichi、Matsushita Takuya、Kira Jun-ichi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 894-894
- DOI
  10.3389/fnins.2018.00894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09694, KAKENHI-PROJECT-16K09721, KAKENHI-PROJECT-17K19663
[Journal Article] Upregulation of Vesicular Glutamate Transporter 2 and STAT3 Activation in the Spinal Cord of Mice Receiving 3,3′-Iminodipropionitrile2017
- Author(s)
  Ohgomori Tomohiro、Yamasaki Ryo、Kira Jun-ichi、Jinno Shozo
- Journal Title
  
  Neurotox Res.
  
  Volume: 未定 Issue: 4 Pages: 768-780
- DOI
  10.1007/s12640-017-9822-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00858, KAKENHI-PLANNED-25117012, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-15H04267
[Journal Article] Lumbar plexus in patients with chronic inflammatory demyelinating polyneuropathy: Evaluation with 3D nerve-sheath signal increased with inked rest-tissue rapid acquisition of relaxation enhancement imaging (3D SHINKEI).2017
- Author(s)
  Hiwatashi A, Togao O, Yamashita K, Kikuchi K, Kamei R, Momosaka D, Ogata H, Yamasaki R, Yoneyama M, Kira JI, Honda H
- Journal Title
  
  Eur J Radiol
  
  Volume: 93 Pages: 95-99
- DOI
  10.1016/j.ejrad.2017.05.031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10408
[Journal Article] Apomorphine therapy for neuronal insulin resistance in a mouse model of Alzheimer's disease2017
- Author(s)
  Nakamura N, Ohyagi Y, Imamura T, Yanagihara YT, Iinuma KM, Soejima N, Murai H, Yamasaki R, Kira J
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461274
[Journal Article] HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis2017
- Author(s)
  Shinoda Koji、Matsushita Takuya、Nakamura Yuri、Masaki Katsuhisa、Yamasaki Ryo、Yamaguchi Hiroo、Togao Osamu、Hiwatashi Akio、Kira Jun-ichi
- Journal Title
  
  Multiple Sclerosis Journal
  
  Volume: 印刷中 Issue: 6 Pages: 710-720
- DOI
  10.1177/1352458517707067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09343, KAKENHI-PROJECT-17K16125, KAKENHI-PROJECT-17K19663
[Journal Article] Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study.2017
- Author(s)
  Yamasaki R, Yamaguchi H, Matsushita T, Fujii T, Hiwatashi A, *Kira JI.
- Journal Title
  
  J Neuroinflammation
  
  Volume: 14 Issue: 1 Pages: 89-89
- DOI
  10.1186/s12974-017-0863-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-25117001, KAKENHI-PLANNED-25117012
[Journal Article] Differential activation of neuronal and glial STAT3 in the spinal cord of the SOD1 G93A mouse model of amyotrophic lateral sclerosis2017
- Author(s)
  Ohgomori Tomohiro、Yamasaki Ryo、Takeuchi Hideyuki、Kadomatsu Kenji、Kira Jun-ichi、Jinno Shozo
- Journal Title
  
  Eur J Neurosci.
  
  Volume: 46 Issue: 4 Pages: 2001-2014
- DOI
  10.1111/ejn.13650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00858, KAKENHI-PROJECT-16H05139, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-15H04267, KAKENHI-PROJECT-15K09338
[Journal Article] Differential involvement of vesicular and glial glutamate transporters around spinal α-motoneurons in the pathogenesis of SOD1G93A mouse model of amyotrophic lateral sclerosis2017
- Author(s)
  Ohgomori Tomohiro、Yamasaki Ryo、Takeuchi Hideyuki、Kadomatsu Kenji、Kira Jun-ichi、Jinno Shozo
- Journal Title
  
  Neuroscience.
  
  Volume: 356 Pages: 114-124
- DOI
  10.1016/j.neuroscience.2017.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00858, KAKENHI-PROJECT-16H05139, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-15H04267
[Journal Article] Re-emergence of a tumefactive demyelinating lesion after initiation of fingolimod therapy2017
- Author(s)
  Hashimoto Y, Shinoda K, Tanaka E, Uehara T, Matsushita T, Yamasaki R, Kira JI.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 379 Pages: 167-168
- DOI
  10.1016/j.jns.2017.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09343, KAKENHI-PROJECT-17K16125
[Journal Article] Efficacy of intravenous methylprednisolone pulse therapy in patients with multiple sclerosis and neuromyelitis optica2016
- Author(s)
  Yamasaki R, Matsushita T, Fukazawa T, Yokoyama K, Fujihara K, Ogino M, Yokota T, Miyamoto K, Niino M, Nomura K, Tomioka R, Tanaka M, Kawachi I, Ohashi T, Kaida KI, Matsui M, Nakatsuji Y, Ochi H, Fukaura H, Kanda T, Nagaishi A, Togo K, Mizusawa H, Murai H, Kira JI
- Journal Title
  
  Multiple sclerosis
  
  Volume: 印刷中 Issue: 10 Pages: 1337-1348
- DOI
  10.1177/1352458515617248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461289, KAKENHI-PROJECT-25293204
[Journal Article] Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation2016
- Author(s)
  Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Matsushita T, Suzumura A, Kira JI.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 38387-38387
- DOI
  10.1038/srep38387
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-25117001, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-16H02657, KAKENHI-PROJECT-26461295, KAKENHI-PROJECT-15K15341, KAKENHI-PROJECT-15K19489
[Journal Article] Early- and late-activated microglia show distinct localization and exert different impact on TDP-43 pathology in amyotrophic lateral sclerosis spinal cord2016
- Author(s)
  Shintaro Hayashi, Ryo Yamasaki, et al.
- Journal Title
  
  Amyotroph Lateral Scler Frontotemporal Degener
  
  Volume: 17 Issue: sup1 Pages: 70-71
- DOI
  10.1080/21678421.2016.1231971
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09721
[Journal Article] Allergic Inflammation Leads to Neuropathic Pain via Glial Cell Activation.2016
- Author(s)
  Yamasaki R, et al
- Journal Title
  
  J Neurosci
  
  Volume: 36 Pages: 11929-11945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461295
[Journal Article] Allergic inflammation leads to neuropathic pain via glial cell activation2016
- Author(s)
  Yamasaki R, Fujii T, Qang B, Masaki K, A Kido M, Yoshida M, Matsushita T, Kira JI.
- Journal Title
  
  The journal of neuroscience
  
  Volume: 36(47) Issue: 47 Pages: 11929-11945
- DOI
  10.1523/jneurosci.1981-16.2016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-25117001, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-15K19492
[Journal Article] アトピー性脊髄炎2014
- Author(s)
  山崎亮、吉良潤一
- Journal Title
  
  神経症候群II．－その他の神経疾患を含めて－[第２版]．日本臨牀
  
  Volume: 別冊 Pages: 822-826
- NAID
  10008119866
- Data Source
  KAKENHI-PLANNED-25117012
[Journal Article] Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model.2014
- Author(s)
  Cui Y and Masaki K et al
- Journal Title
  
  J Neuroinflammation
  
  Volume: 11 Issue: 1 Pages: 42-42
- DOI
  10.1186/1742-2094-11-42
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790889, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-25293204, KAKENHI-PROJECT-25461282, KAKENHI-PROJECT-25461317, KAKENHI-PROJECT-26461295
[Journal Article] Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese.2014
- Author(s)
  Ainiding G, Kawano Y, Sato S, Isobe N, Matsushita T, Yoshimura S, Yonekawa T, Yamasaki R, Murai H, Kira J
- Journal Title
  
  J Neurol Sci
  
  Volume: 337 Pages: 147-150
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-25117012
[Journal Article] Early inhibition of TNF-α and IL-6 in muscle tissues as a therapy for dystrophinopathy in mdx mice2014
- Author(s)
  Arahata H, Ohyagi Y, Iinuma KM, Tanaka M, Tateishi T, Yamasaki R, Matsushita T, Kira J
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 5 Issue: 3 Pages: 371-377
- DOI
  10.1111/cen3.12111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461274
[Journal Article] Microglia in vivo and in vitro2014
- Author(s)
  Yamasaki R
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 5 Pages: 114-116
- Data Source
  KAKENHI-PLANNED-25117012
[Journal Article] A case of neuromyelitis optica harboring both anti-aquaporin-4 antibodies and a pathogenic mitochpondrial DNA mutation for Leber’s hereditary optic neuropathy2014
- Author(s)
  Shiraishi W, Hayashi S, Kamada T, Isobe N, Yamasaki R, Murai H, Ohyagi Y, Kira J
- Journal Title
  
  Multiple Sclerosis
  
  Volume: 20 Issue: 2 Pages: 258-260
- DOI
  10.1177/1352458513513057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461274
[Journal Article] Chharacteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis2013
- Author(s)
  Matsushita T, Tateishi T, Isobe N, Yonekawa T, Yamasaki R, Murai H, Kira J
- Journal Title
  
  PLos ONE
  
  Volume: 8 Issue: 4 Pages: e61835-e61835
- DOI
  10.1371/journal.pone.0061835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390178, KAKENHI-PROJECT-23790996, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-25670423, KAKENHI-PROJECT-25860716
[Journal Article] TAR DNA-binding protein 43 pathology in a case clinically diagnosed with facial-onset sensory and motor neuronopathy syndrome: an autopsied case report and a review of the literature.2013
- Author(s)
  Sonoda K, Sasaki K, Tateishi T, Yamasaki R, Hayashi S, Sakae N, Ohyagi Y, Iwaki T, Kira J.
- Journal Title
  
  J Neurol Sci
  
  Volume: 332 Issue: 1-2 Pages: 148-153
- DOI
  10.1016/j.jns.2013.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461282
[Journal Article] Anti-neurofascin antibody in patients with combined central and peripheral demyelination2013
- Author(s)
  Nobutoshi Kawamura, Ryo Yamasaki, Tomomi Yonekawa, Takuya Matsushita, Susumu Kusunoki, Shigemi Nagayama, Yasuo Fukuda, Hidenori Ogata, Dai Matsuse, Hiroyuki Murai, Jun-ichi Kira
- Journal Title
  
  Neurology
  
  Volume: 81 Issue: 8 Pages: 714-722
- DOI
  10.1212/wnl.0b013e3182a1aa9c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591265, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-25461282, KAKENHI-PROJECT-25670423, KAKENHI-PROJECT-25860716
[Journal Article] Connexin 43 astrocytopathy linked to rapidly progressive multiple sclerosis and neuromyelitis optica.2013
- Author(s)
  Masaki K et al
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 8 Pages: e72919-e72919
- DOI
  10.1371/journal.pone.0072919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790889, KAKENHI-PLANNED-25117012
[Journal Article] Connexin 43 astrocytopathy linked to rapidly progressive multiple sclerosis and neuromyelitis optica.2013
- Author(s)
  Masaki K, Suzuki SO, Matsushita T, Matsuoka T, Imamura S, Yamasaki R, Suzuki M, Suenaga T, Iwaki T, Kira J.
- Journal Title
  
  PLoS One.
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461282
[Journal Article] A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese.2013
- Author(s)
  Huang J, Yoshimura S, Isobe N, Matsushita T, Yonekawa T, Sato S, Yamasaki R, Kira J; South Japan Multiple Sclerosis Genetics Consortium.
- Journal Title
  
  Multiple Sclerosis Journal
  
  Volume: 19 Issue: 13 Pages: 1696-1703
- DOI
  10.1177/1352458513482512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790890, KAKENHI-PLANNED-25117012
[Journal Article] A case of hereditary diffuse leukoencephalopathy with axonal spheroids caused by a de novo mutation in CSF1R masquerading as primary progressive multiple sclerosis.2013
- Author(s)
  Saitoh BY, Yamasaki R, Hayashi S, Yoshimura S, Tateishi T, Ohyagi Y, Murai H, Iwaki T, Yoshida K, Kira J.
- Journal Title
  
  Mult Scler.
  
  Volume: 10 Issue: 10 Pages: 1367-1370
- DOI
  10.1177/1352458513489854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461282
[Journal Article] Impaired cytoplastic-nuclear transport of hypoxia-inducible factor-1αin amgotrophic lateral sclerosis.2013
- Author(s)
  Kira J et al
- Journal Title
  
  Brain Pathol
  
  Volume: - Issue: 5 Pages: 534-546
- DOI
  10.1111/bpa.12040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659459, KAKENHI-PROJECT-23790997, KAKENHI-PLANNED-25117012, KAKENHI-PROJECT-25461317
[Presentation] Exosome GJA1-29k is a blood marker for progressive multiple sclerosis reflecting glial inflammation2023
- Author(s)
  Guzailiayi Maimaitijiang, Jun-ichi Kira, Ayako Sakoda, Katsuhisa Masaki, Mitsuru Watanabe, Satoshi Nagata, Ezgi Ozdemir, Ryo Yamasaki, Noriko Isobe, Xu Zhang, Tomohiro Imamura, Yuri Nakamura
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07467
[Presentation] 活性化ミクログリアが産生する蛋白に着目した運動神経細胞変性相関因子の同定と診断バイオマーカーの探求2023
- Author(s)
  林信太郎、山﨑亮、小早川優子、他.
- Organizer
  第35回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07517
[Presentation] Identification of a unique microglia population exacerbating multiple system atrophy2023
- Author(s)
  松瀬大, 山口浩雄, 西村由宇慈, 眞﨑勝久, 田中辰典, 雑賀徹, 原田雅也, 田中謙二, 山﨑亮, 磯部紀子, 吉良潤一
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] Calretinin activates microglia to produce CC-motif ligand 2 relevant to clinical severity of ALS2023
- Author(s)
  Hayashi S, Yamasaki R, Kobayakawa Y, et al.
- Organizer
  34th International Symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07517
[Presentation] A centrally acting connexin hemichannel blocker attenuates multiple system atrophy-cerebellar type2023
- Author(s)
  原田雅也, 眞﨑勝久, 松瀨大, 山口浩雄, 西村由宇慈, オズデミールエズギ, 田中栄蔵, 田中辰典, 山﨑亮, 竹内英之, 谷脇考恭, 磯部紀子, 吉良潤一
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] Early and extensive alterations of glial connexins in multiple system atrophy2023
- Author(s)
  眞崎勝久, 西村由宇慈, 松瀬大, 山口浩雄, 田中辰典, 貞島祥子, 笹ケ迫直一, 山﨑亮, 岩城徹, 磯部紀子, 吉良潤一
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] Anti-Annexin A2 autoantibodies relate to neuropathic pain2023
- Author(s)
  Kaoru Kashu, Takayuki Fujii, Hidenori Ogata, Sato Yoshidomi, Ryo Yamasaki, Noriko Isobe.
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06945
[Presentation] 末梢性神経障害性疼痛患者における抗Annexin A2抗体の保有率および抗体陽性患者の臨床的特徴の解明2023
- Author(s)
  賀集薫、藤井敬之、緒方英紀、吉富小都、山﨑亮、磯部紀子.
- Organizer
  第34回日本末梢神経学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06945
[Presentation] Marked upregulation of GPR17-positive premyelinating oligodendrocytes in multiple system atrophy2023
- Author(s)
  西村由宇慈, 眞﨑勝久, 松瀬大, 山口浩雄, 田中辰典, 貞島祥子, 笹ケ迫直一, 山﨑亮, 本田裕之, 磯部紀子, 岩城徹, 吉良潤一
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] Calretinin activates microglia to produce CC-motif ligand 2 relevant to clinical severity of ALS2023
- Author(s)
  Hayashi S, Yamasaki R, Kobayakawa Y, et al.
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07517
[Presentation] 中枢作用コネキシン阻害薬を用いた多系統萎縮症モデルマウスに対する治療効果の検討2023
- Author(s)
  原田雅也，眞﨑勝久，松瀨大，山口浩雄，西村由宇慈，高瀬オズデミールエズギ，田中栄蔵，田中辰典，山﨑亮，竹内英之，谷脇考恭，磯部紀子，吉良潤一
- Organizer
  第35回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] 神経障害性疼痛患者における抗Annexin A2抗体の保有率および抗体陽性患者の臨床的特徴の解明2023
- Author(s)
  賀集薫、藤井敬之、緒方英紀、吉富小都、山﨑亮、磯部紀子.
- Organizer
  第35回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06945
[Presentation] Early and extensive alterations of glial connexins in multiple system atrophy2023
- Author(s)
  Katsuhisa Masaki, Yuji Nishimura, Dai Matsuse, Hiroo Yamaguchi, Tatsunori Tanaka, Shoko Sadashima, Naokazu Sasagasako, Ryo Yamasaki, Noriko Isobe, Toru Iwaki, Jun-ichi Kira
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06965
[Presentation] Early loss of connexin 32 in multiple system atrophy; implication for pathogenesis of demyelination2022
- Author(s)
  Yuji NIshimura, Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Tatsunori Tanaka, Shoko Sadashima, Ryo Yamasaki, Toru Iwaki, Noriko Isobe, Jun-ichi Kira
- Organizer
  63rd Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] .Identification of synucleinopathy associated microglia in a novel mouse model of multiple system atrophy (MSA)-cerebellar type2022
- Author(s)
  Hiroo Yamaguchi, Yuji Nishimura, Dai Matsuse, Katsuhisa Masaki, Tatsunori Tanaka, Toru Saiga, Masaya Harada, Kenji Tanaka, Ryo Yamasaki, Noriko lsobe, Jun-ichi Kira.
- Organizer
  Neuroscience 2022 (San Diego, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] A population of inflammatory microglia exacerbates a novel mouse model of multiple system atrophy.2022
- Author(s)
  Dai Matsuse, Hiroo Yamaguchi, Katsuhisa Masaki, Yuji Nishimura, Tatsunori Tanaka, Toru Saiga, Kenji Tanaka, Ryo Yamasaki, Noriko Isobe, Jun-ichi Kira.
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] The first evaluation of calretinin in the spinal axons encompassed in anterolateral funiculi outside the cortical tract and cerebrospinal fluids of ALS patients.2022
- Author(s)
  Hayashi S, Yamasaki R, Kobayakawa Y, Kira JI, Isobe N.
- Organizer
  33rd International Symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07517
[Presentation] The first evaluation of calretinin in the spinal axons and cerebrospinal fluids of ALS patients.2022
- Author(s)
  Hayashi S, Yamasaki R, Kobayakawa Y, Kira JI, Isobe N.
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07517
[Presentation] Synucleinopathy-associated microglia uncovered by a novel multiple system atrophy-cerebellar type (MSA-C) mouse model.2022
- Author(s)
  Jun-ichi Kira, Hiroo Yamaguchi, Yuji Nishimura, Dai Matsuse, Katsuhisa Masaki, Ryo Yamasaki, Noriko Isobe.
- Organizer
  The 147th Annual Meeting of the American Neurological Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] Identification of synucleinopathy associated microglia in a novel mouse model of multiple system atrophy (MSA)-cerebellar type2022
- Author(s)
  Hiroo Yamaguchi, Yuji Nishimura, Dai Matsuse, Katsuhisa Masaki, Tatsunori Tanaka, Toru Saiga, Masaya Harada, Kenji Tanaka, Ryo Yamasaki, Noriko Isobe, Jun-ichi Kira
- Organizer
  Neuroscience 2022
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] Exosomal GJA1-29k translational isoform is a novel blood biomarker for neuroinflammation in neuromyelitis optica.2022
- Author(s)
  Guzailiayi Maimaitijiang, Jun-ichi Kira, Yuri Nakamura, Mitsuru Watanabe, Ayako Sakoda, Katsuhisa Masaki, Satoshi Nagata, Hiroo Yamaguchi, Ryo Yamasaki, Noriko Isobe, Xu Zhang, Tomohiro Imamura
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07467
[Presentation] 多系統萎縮症におけるconnexin蛋白群の早期かつ広範な変化と脱髄病態との関連2022
- Author(s)
  西村由宇慈, 眞崎勝久, 松瀬大, 山口浩雄, 田中辰典, 貞島祥子, 笹ヶ迫直一, 山崎亮, 磯部紀子, 岩城徹, 吉良潤一
- Organizer
  第34回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07889
[Presentation] C-C chemokine receptor2+ macrophages in nerves ameliorate motor neuron disease model mice2022
- Author(s)
  山﨑亮、白石渉、橋本侑、江千里、磯部紀子
- Organizer
  第63回日本神経学会学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07963
[Presentation] A population of inflammatory microglia exacerbates a novel mouse model of multiple system atrophy2022
- Author(s)
  Dai Matsuse, Hiroo Yamaguchi, Katsuhisa Masaki, Yuji Nishimura, Tatsunori Tanaka, Toru Saiga, Kenji Tanaka, Ryo Yamasaki, Noriko Isobe, Jun-ichi Kira
- Organizer
  63rd Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] カルシウム結合蛋白に着目したミクログリアからの筋萎縮性側索硬化症重症度関連ケモカイン放出因子の解明.2022
- Author(s)
  林信太郎、山﨑亮、吉良潤一、磯部紀子.
- Organizer
  第34回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07517
[Presentation] Clearance of peripheral nerve misfolded mutant protein by infiltrated macrophages correlates with motor neuron disease progression2022
- Author(s)
  山﨑亮、白石渉、橋本侑、江千里、小早川優子、磯部紀子
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07963
[Presentation] 多系統萎縮症におけるconnexin蛋白群の早期かつ広範な変化と脱髄病態との関連2022
- Author(s)
  西村由宇慈, 眞崎勝久, 松瀬大, 山口浩雄, 田中辰典, 貞島祥子, 笹ヶ迫直一, 山崎亮, 磯部紀子, 岩城徹, 吉良潤一
- Organizer
  第34回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] Synucleionopathy-Associated Microglia Uncovered by a Novel Multiple System Atrophy-Cerebellar Type (MSA-c) Mouse Model2022
- Author(s)
  Jun-ichi Kira, Hiroo Yamaguchi, Yuji Nishimura, Dai Matsuse, Katsuhisa Masaki, Ryo Yamasaki, Noriko Isobe
- Organizer
  147th American Neurological Association (ANA)
- Data Source
  KAKENHI-PROJECT-22K07540
[Presentation] 小脳型多系統萎縮症/一次進行型多発性硬化症モデルマウスの樹立とこれら疾患の新規創薬ターゲットの探索2021
- Author(s)
  山口浩雄、松瀬大、眞﨑勝久、雑賀徹、西村由宇慈、田中辰典、田中謙二、山﨑亮、吉良潤一、磯部紀子
- Organizer
  第39回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] LGI4 is a novel autoantigen for nodopathy/paranodopathy type chronic inflammatory demyelinating polyneuropathy2021
- Author(s)
  Xu Zhang, Hidenori Ogata, Tomohiro Imamura, Takayuki Fujii, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  American Neurological Association 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] 新規小脳型多系統萎縮症モデルのCSF-1R阻害剤治療.2021
- Author(s)
  松瀬大, 山口浩雄, 眞﨑勝久, 西村由宇慈, 田中辰典, 雑賀徹, 田中謙二, 山﨑亮, 吉良潤一, 磯部紀子
- Organizer
  第15回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] Iguratimod improves a secondary progressive multiple sclerosis (SPMS) model by therapeutic administration.2021
- Author(s)
  Satoshi Nagata, Ryo Yamasaki, Ezgi Ozdemir, Hiroo Yamaguchi, Katsuhisa Masaki, Jun-ichi Kira, Noriko Isobe:
- Organizer
  15th Congress of the International Society of Neuroimmunology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] 軸索蛋白であるカルレチニンはミクログリアを刺激し ALSの臨床的重症度と相関するケモカインを産生させる2021
- Author(s)
  林信太郎、山﨑亮、吉良潤一
- Organizer
  第33回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] Axonal protein, calretinin, stimulates microglia to produce chemokines associated with clinical severity of ALS2021
- Author(s)
  Shintaro Hayashi, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  32nd International Symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] Eliminaion of CSF1R-positive microglia exacerbates a novel mouse model of multiple system atrophy2021
- Author(s)
  西村由宇慈, 真崎勝久, 松瀬大, 山口浩雄, 雑賀徹, 田中辰典, 貞島祥子, 山崎亮, 田中謙二, 岩城徹, 吉良潤一
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] Early dysregulation of connexins in astroglia and oligodendroglia in multiple system atrophy2021
- Author(s)
  眞崎勝久, 西村由宇慈, 松瀬大, 山口浩雄, 雑賀徹, 田中辰典, 貞島祥子, 山崎亮, 田中謙二, 岩城徹, 吉良潤一
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症モデルの樹立2021
- Author(s)
  松瀬大, 山口浩雄, 眞﨑勝久, 西村由宇慈, 田中辰典, 雑賀徹, 田中謙二, 山﨑亮, 吉良潤一
- Organizer
  第14回日本パーキンソン病・運動障害疾患学会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] Glial assembly via gap junction controls CNS disorders: insights from disease model mice.2021
- Author(s)
  Ryo Yamasaki, Yinan Zhao, Marion Wijering, Mei Fang, Hayato Une, Guangrui Li, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  17th Asian Oceanian Congress of Neurology (AOCN 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] 新規小脳型多系統萎縮症モデルのCSF-1R阻害剤治療2021
- Author(s)
  松瀬大、山口浩雄、眞﨑勝久、西村由宇慈、田中辰典、雑賀徹、田中謙二、山﨑亮、吉良潤一、磯部紀子
- Organizer
  第15回パーキンソン病運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症モデルの樹立2021
- Author(s)
  松瀬大、山口浩雄、眞﨑勝久、西村由宇慈、田中辰典、雑賀徹、田中謙二、山﨑亮、吉良潤一
- Organizer
  第14回パーキンソン病運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] Axonal proteins stimulate microglia to produce pro-inflammatory cytokines relevant to ALS2021
- Author(s)
  林信太郎、山﨑亮、吉良潤一
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] カルシウム結合蛋白によるグリア炎症惹起性の検証-筋萎縮性側索硬化症患者の脳脊髄液所見との比較-2020
- Author(s)
  林信太郎、山崎亮、吉良潤一
- Organizer
  第32回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] Frequent subclinical cranial nerve involvement in anti-neurofascin 155 antibody-positive CIDP2020
- Author(s)
  Ogata H, Zhang X, Inamizu S, Yamasaki R, Matsushita T, Isobe N, Kira J
- Organizer
  2020 Peripheral Nerve Society Annual Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] Drug targets for multiple system atrophy and primary progressive multiple sclerosis by a novel model2020
- Author(s)
  西村由宇慈, 真崎勝久, 松瀬大, 山口浩雄, 雜賀徹, 田中辰典, 渡邊充, 山﨑亮, 田中謙二, 吉良潤一
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] Two subtypes of anti-neurofascin 155/contactin-1 antibody-negative CIDP by CSF cytokine profiling2020
- Author(s)
  Zhang X, Ogata H, Yamasaki R, Kaida K, Kuwahara M, Kusunoki S, Matsushita T, Isobe N, Kira J
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] Drug targets for multiple system atrophy and primary progressive multiple sclerosis by a novel model2020
- Author(s)
  Yuji Nishimura, Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Toru Saiga, Tatsunori Tanaka, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  61ｓｔ Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] Gene expression profile of multiple system atrophy/primary progressive multiple sclerosis mice model2020
- Author(s)
  Hiroo Yamaguchi, Tasunori Tanaka, Dai Mtasuse, Yuji Nishimura, Katsuhisa Masaki, Toru Saiga, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  61ｓｔ Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] Gene expression profile of multiple system atrophy/primary progressive multiple sclerosis mice model.2020
- Author(s)
  Yamaguchi Hiroo, Tanaka Tatsunori, Matsuse Dai, Nishimura Yuji, Masaki Katsuhisa, Saiga Toru, Watanabe Mitsuru, Yamasaki Ryo, Tanaka Kenji, Kira Jun-ichi
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] 新規小脳型多系統萎縮症モデルによる脱髄・神経細胞障害機序とグリア制御による新規治療法開発の試み2020
- Author(s)
  西村由宇慈, 眞﨑勝久, 松瀬大, 山口浩雄, 雑賀徹, 田中辰典, 田中謙二, 山﨑亮, 岩城徹, 吉良潤一.
- Organizer
  第32回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] 多系統萎縮症および一次進行型多発性硬化症モデルマウスを用いた治療標的探索2020
- Author(s)
  田中辰典、西村由宇慈、真崎勝久、松瀬大、山口浩雄、雑賀徹、渡邊充、山崎亮、田中謙二、吉良潤一
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] Therapeutic drug search using model mice for multiple system atrophy and primary progressive multiple sclerosis.2020
- Author(s)
  Tanaka Tatsunori, Nishimura Yuji, Masaki Katsuhisa, Matsuse Dai, Yamaguchi Hiroo, Saiga Toru, Watanabe Mitsuru, Yamasaki Ryo, Tanaka Kenji, Kira Jun-ichi
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症モデルの樹立2020
- Author(s)
  松瀬大, 山口浩雄, 眞﨑勝久, 西村由宇慈, 田中辰典, 雑賀徹, 田中謙二, 山﨑亮, 吉良潤一
- Organizer
  第14回日本パーキンソン病・運動障害疾患学会（Movement Disorder Society-Japan）
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] Gene expression profile of multiple system atrophy/primary progressive multiple sclerosis mice model2020
- Author(s)
  山口浩雄, 田中辰典, 松瀬大, 西村由宇慈, 真崎勝久, 雑賀徹, 渡邊充, 山﨑亮, 田中謙二, 吉良潤一
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] Calcium-binding proteins stimulate microglia to induce proinflammatory mediators relevant to ALS2020
- Author(s)
  Hayashi S, Yamasaki R, Okamoto K, KIra J.
- Organizer
  第61回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] Early decrease of peripheral blood intermediate monocytes in multiple system atrophy cerebellar-type.2020
- Author(s)
  Matsuse Dai, Yamasaki Ryo, Maimaitijiang Guzailiayi, Yamaguchi Hiroo, Kira Jun-ichi
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] 新規小脳型多系統萎縮症モデルによる脱髄・神経細胞障害機序とグリア制御による新規治療法開発の試み2020
- Author(s)
  西村由宇慈, 眞﨑勝久, 松瀬大, 山口浩雄, 雑賀徹, 田中辰典, 田中謙二, 山﨑亮, 岩城徹, 吉良潤一
- Organizer
  第32回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] Therapeutic drug search using model mice for multiple system atrophy and primary progressive multiple sclerosis2020
- Author(s)
  Tatsunori Tanaka, Yuji Nishimura, Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Toru Saiga, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka and Jun-ichi Kira
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] Early decrease of peripheral blood intermediate monocytes in multiple system atrophy cerebellar-type2020
- Author(s)
  Dai Matsuse, Ryo Yamasaki, Maimaitjiang Guzailiayi, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  61ｓｔ Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-20K20470
[Presentation] ALS脊髄白質に出現するgalectin-3陽性ミクログリアはTDP-43病理と正相関する2019
- Author(s)
  林信太郎, 山﨑亮, 岡本幸市，吉良潤一
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] Expression of mutant α-synuclein in oligodendrocytes induces remarkable glial inflammation and demyelination in the spinal cord and brainstem/cerebellar white matter: A novel model of multiple system atrophy-cerebellar type and primary progressive multiple sclerosis2019
- Author(s)
  Hiroo Yamaguchi, Dai Matsuse, Katsushisa Masaki, Toru Saiga, Yuji Nishimura, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] 末梢神経浸潤C-Cケモカイン受容体2(CCR2)陽性マクロファージは運動神経細胞を保護する2019
- Author(s)
  山﨑　亮、白石　渉、小早川優子、松瀬　大、吉良潤一
- Organizer
  令和元年度神経変性疾患領域における基盤的調査研究班班会議
- Data Source
  KAKENHI-PROJECT-19K07963
[Presentation] Expression of mutant α-synuclein in oligodendrocytes induces remarkable glial inflammation and demyelination in the spinal cord and brainstem/cerebellar white matter: A novel model of multiple system atrophy-cerebellar type and primary progressive multiple sclerosis2019
- Author(s)
  Hiroo Yamaguchi, Dai Matsuse, Katsushisa Masaki, Toru Saiga, Yuji Nishimura, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症・一次進行型多発性硬化症モデル2019
- Author(s)
  真崎勝久、松瀬大、山口浩雄、雑賀徹、西村由宇慈、田中辰典、渡邉充、田中謙二、山﨑亮、吉良潤一
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] 抗PlexinD1抗体が各種神経疾患における神経障害性疼痛に及ぼす影響.2019
- Author(s)
  山崎亮
- Organizer
  第60回日本神経学会学術大会. 2019.5.23. 大阪.
- Invited
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] A novel model of multiple system atrophy-cerebellar type and primary progressive multiple sclerosis2019
- Author(s)
  Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Toru Saiga, Yuji Nishimura, Tatsunori Tanaka, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  The 24th Annual Meeting of the Japan Glia
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] Central nervous system-specific antinuclear antibodies associated with secondary progression and greater disability in MS.2019
- Author(s)
  Takayuki Fujii, Ryo Yamasaki, Yukino Miyachi, Satoshi Nagata, Guzailiayi Maimaitijiang, Yuri Nakamura, Koji Shinoda, Takuya Matsushita, Noriko Isobe, Jun-ichi Kira
- Organizer
  ECTRIMS 2019. 2019.9.13. Stockholm, Sweden.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] A novel mice model of PPMS/MSA by oligodendroglial overexpression of mutant alpha-synuclein2019
- Author(s)
  Dai Matsuse, Hiroo Yamaguchi, Toru Saiga, Katsuhisa Masaki, Yiwen Cui, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  第42回日本神経科学大会／第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] Macrophage galectin-3 in spinal white matter is a key molecule for TDP-43 pathology in ALS2019
- Author(s)
  林信太郎, 山﨑亮, 岡本幸市，吉良潤一
- Organizer
  第60回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] CCR2-positive peripheral blood macrophages play protective roles in ALS mouse model2019
- Author(s)
  Wataru Shiraishi, Ryo Yamasaki, Yuko Kobayakawa, Jun-ichi Kira
- Organizer
  60th Annual Meeting of The Japanese Society of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07963
[Presentation] A novel mice model of PPMS/MSA by oligodendroglial overexpression of mutant alpha-synuclein2019
- Author(s)
  Dai Matsuse, Hiroo Yamaguchi, Toru Saiga, Katsuhisa Masaki, Yiwen Cui, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  第42回日本神経科学大会／第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] Possible regulatory roles of miRNAs in APP-KI AD model mice2019
- Author(s)
  Tomohiro Imamura, Hirohide Asai, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09757
[Presentation] Microglial galectin-3 in the spinal white matter is a key molecule for motor neuron degeneration in ALS2019
- Author(s)
  Shintaro Hayashi, Ryo Yamasaki, Koichi Okamoto, Jun-ichi Kira
- Organizer
  30th International symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07996
[Presentation] 抗neurofascin 155抗体関連ニューロパチー全国調査結果.2019
- Author(s)
  緒方英紀, 山﨑亮, 磯部紀子, 角谷真人, 海田賢一, 松井真, 桑原聡, 楠進, 吉良潤一
- Organizer
  第31回日本神経免疫学会学術集会. 2019.9.26. 千葉.
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] Quantitative measurement of anti-plexin D1 antibodies by enzyme-linked immunosorbent assay.2019
- Author(s)
  Takayuki Fujii, Ryo Yamasaki, Yukino Miyachi, Kyoko Iinuma, Jun-ichi Kira
- Organizer
  60th Annual Meeting of The Japanese Society of Neurology. 2019.5.24. Osaka, Japan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] 抗neurofascin 155抗体陽性慢性炎症性脱髄性多発神経炎.2019
- Author(s)
  緒方英紀, 山﨑亮, 吉良潤一
- Organizer
  第30回日本末梢神経学会学術集会. 2019.8.23. 石川.
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] 二次進行型多発性硬化症(SPMS)新規動物モデルの樹立と炎症性グリアを標的とした進行型多発性硬化症治療薬開発2019
- Author(s)
  吉良潤一、○山﨑亮、松下拓也、篠田紘司、竹内英之、中川昌也
- Organizer
  神経免疫合同班会議
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] A novel model of multiple system atrophy-cerebellar type and primary progressive multiple sclerosis2019
- Author(s)
  Katsuhisa Masaki, Dai Matsuse, Hiroo Yamaguchi, Toru Saiga, Yuji Nishimura, Tatsunori Tanaka, Mitsuru Watanabe, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  The 24th Annual Meeting of the Japan Glia
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] A novel model of primary progressive multiple sclerosis by oligodendroglial mutant alpha-synuclein2019
- Author(s)
  Toru Saiga, Hiroo Yamaguchi, Dai Matsuse, Katsuhisa Masaki, Yiwen Cui, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07976
[Presentation] オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症・一次進行型多発性硬化症モデル2019
- Author(s)
  真崎勝久、松瀬大、山口浩雄、雑賀徹、西村由宇慈、田中辰典、渡邉充、田中謙二、山﨑亮、吉良潤一
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] Association CD33 expression with toxic turn amyloid βprotein 42 in APP-KI mice2019
- Author(s)
  Tomohiro Imamura, Hirohide Asai, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09757
[Presentation] The first nationwide survey results of IgG4 anti-neurofascin155 (NF155) antibody-positive neuropathy.2019
- Author(s)
  Hidenori Ogata, Ryo Yamasaki, Masato Kadoya, Kenichi Kaida, Makoto Matsui, Satoshi Kuwabara, Susumu Kusunoki, Noriko Isobe, Jun-ichi Kira
- Organizer
  60th Annual Meeting of The Japanese Society of Neurology. 2019.5.22. Osaka, Japan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] A novel model of primary progressive multiple sclerosis by oligodendroglial mutant alpha-synuclein2019
- Author(s)
  Toru Saiga, Hiroo Yamaguchi, Dai Matsuse, Katsuhisa Masaki, Yiwen Cui, Ryo Yamasaki, Kenji Tanaka, Jun-ichi Kira
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K07501
[Presentation] Anti-plexin D1 antibody and painful neuropathy.2019
- Author(s)
  Takayuki Fujii, Ryo Yamasaki, Yukino Miyachi, Kyoko Iinuma, Jun-ichi Kira
- Organizer
  60th Annual Meeting of The Japanese Society of Neurology. 2019.5.22. Osaka, Japan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] CSF cytokine profile and HLA haplotype in IgG4 anti-neurofascin 155 (NF155) antibody-positive CIDP.2019
- Author(s)
  Ryo Yamasaki, Hidenori Ogata, Xu Zhang, Akira Machida, Nobutoshi Morimoto, Kenichi Kaida, Teruaki Masuda, Yukio Ando, Motoi Kuwahara, Susumu Kusunoki, Jun-ichi Kira
- Organizer
  60th Annual Meeting of The Japanese Society of Neurology. 2019.5.22. Osaka, Japan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01045
[Presentation] 孤発性筋萎縮性側索硬化症の非症候性脊髄と症候性脊髄におけるグリア炎症の免疫病理学的解析2018
- Author(s)
  林信太郎、山﨑亮、吉良潤一、他.
- Organizer
  第30回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] Astroglial connexin (Cx)30 and Cx43 and oligodendroglial Cx47 differentially modulate acute and chronic experimental autoimmune encephalomyelitis2018
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Hiroo Yamaguchi
- Organizer
  International Society of Neuroimmunology Congress 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Focal cortical astrocytopathy with demyelination in neuromyelitis optica spectrum disorder2018
- Author(s)
  Shotaro Hayashida, Katsuhisa Masaki, Satoshi O. Suzuki, Takuya Matsushita, Ryo Yamasaki, Toshihiko Suenaga, Kazuya Takahashi, Toru Iwaki, Jun-ichi Kira
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Pathological study of glial inflammation in clinically pre-symptomatic spinal cords in patients with sporadic amyotrophic lateral sclerosis2018
- Author(s)
  Hayashi S, Yamasaki R, Kira JI, et al.
- Organizer
  29th International Symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] Oligodendroglia-specific conditional ablation of connexin 47 is sufficient to produce relapse and progression in demyelinating disease2018
- Author(s)
  Yinan Zhao, Ryo Yamasaki, Marion Wijering, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  第30回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Oligodendroglia-specific conditional ablation of connexin 47 is sufficient to produce relapse and　progression in demyelinating disease2018
- Author(s)
  Yinan Zhao, Ryo Yamasaki, Marion Wijering, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  第30回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Astroglial connexin (Cx)30 and Cx43 and oligodendroglial Cx47 differentially modulate acute and chronic experimental autoimmune encephalomyelitis2018
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Hiroo Yamaguchi
- Organizer
  International Society of Neuroimmunology Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Oligodendroglia-specific connexin47 deletion produces a relapse-remitting multiple sclerosis model2018
- Author(s)
  Ryo Yamasaki MD, PhD, Yinan Zhao MD, Marion Wijering BS, Hiroo Yamaguchi MD, PhD, Jun-ichi Kira MD, PhD.
- Organizer
  第59回日本神経学会学術大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Elucidation of the effects of gap junction protein connexin on the pathogenesis of multiple sclerosis model mice and development of new therapeutic options by functional modification ギャップ結合蛋白コネキシンが多発性硬化症モデルマウスの病態に及ぼす影響の解析2018
- Author(s)
  Ryo Yamasaki MD, PhD, Yinan Zhao MD, Marion Wijering BS, Mei Fang MD, Guangrui Li MD, PhD, Hayato Une MD, Hiroo Yamaguchi MD, PhD, Jun-ichi Kira MD, PhD.
- Organizer
  第61回日本神経化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Revisiting glia; as a mother and guardian of central nervous system2018
- Author(s)
  Ryo　Yamasaki MD, PhD
- Organizer
  第59回日本神経学会学術大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] 多発性硬化症ではインターフェロンβ治療によるVδ1-Vδ2-Vγ9- γδ型T細胞の増加が良好な予後と関連する2018
- Author(s)
  グザリアイ・マイマイテジャン、渡邉充、篠田紘司, 中村優理、真崎勝久、松下拓也、山﨑亮、吉開泰信、吉良潤一
- Organizer
  第30回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] A novel secondary progressive multiple sclerosis model by oligodendroglia-specific inducible conditional knockout of connexin 472018
- Author(s)
  Ryo Yamasaki MD, PhD, Yinan Zhao MD, Marion Wijering BS, Hiroo Yamaguchi MD, PhD, Jun-ichi Kira MD, PhD.
- Organizer
  International Society of Neuroimmunology Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Oligodendroglia-specific connexin47 deletion produces a relapse-remitting multiple sclerosis model2018
- Author(s)
  Ryo Yamasaki, Yinan Zhao, Marion Wijering, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Altered gd T Cell repertoire correlates with disability in untreated Multiple Sclerosis2018
- Author(s)
  Guzailiayi Maimaitijiang, Koji Shinoda, Mitsuru Watanabe, Yuri Nakamura, Katsuhisa Masaki, Takuya Matsushita, Ryo Yamasaki, Yasunobu Yoshikai, Jun-ichi Kira
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] 筋萎縮性側索硬化症の新たな病態：ギャップ結合蛋白コネキシン機能異常や末梢神経炎症を介した病態機序の解明2018
- Author(s)
  山﨑亮、小早川優子、白石渉、山口浩雄、眞﨑勝久、渡邉充、藤田篤史、藤井敬之、宇根隼人、斎藤万有、崔訳文、方梅、李広瑞、趙奕楠、ウルファ・カメリア・インディアサリ、○吉良潤一
- Organizer
  グリアアセンブリ第5回班会議・成果報告会
- Data Source
  KAKENHI-PROJECT-15K09342
[Presentation] Detection of early glial inflammation in pre-symptomatic spinal cords of amyotrophic lateral sclerosis2018
- Author(s)
  Hayashi S, Yamasaki R, Kira JI, et al.
- Organizer
  第59回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] A novel secondary progressive multiple sclerosis model by oligodendroglia-specific inducible conditional knockout of connexin 472018
- Author(s)
  Ryo Yamasaki, Yinan Zhao, Marion Wijering, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  International Society of Neuroimmunology Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Astroglial connexin 30 deletion leads to hypersensitivity in a MPTP mouse model of Parkinson’s disease2017
- Author(s)
  Atsushi Fujita, 〇Hiroo Yamaguchi, Ryo Yamasaki, Yuta Matsuoka, Ken-ichi Yamada, Jun-ichi Kira
- Organizer
  XXIII World Congress of Neurology（WCN2017）
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] T-05-040C Astrocytic connexin 30 deletion leads to hypersensitivity in a MPTP mouse model of Parkinson’s disease2017
- Author(s)
  Atsushi Fujita, MD,1 Hiroo Yamaguchi, MD, PhD,1 Ryo Yamasaki, MD, PhD,1 Yuta Matsuoka, PhD,2 Ken-ichi Yamada, PhD,2 Jun-ichi Kira, MD, PhD
- Organizer
  Euroglia2017
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Deviated Repertoire of γδT Cells is Associated with Disease Severity of Multiple Sclerosis.2017
- Author(s)
  Maimaitijiang Guzailiayi, Koji Shinoda, Yuri Nakamura, Takuya Matsushita, Ryo Yamasaki, Yasunobu Yoshikai, Jun-ichi Kira
- Organizer
  the 10th Congress of the Pan-Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Early strong intrathecal inflammation in cerebellar type multiple system atrophy (MSA-C) based on cerebrospinal fluid cytokine and chemokine profiles2017
- Author(s)
  Ryo Yamasaki, Hiroo Yamaguchi, Takuya Matsushita, Takayuki Fujii, Akio Hiwatashi, Jun-ichi Kira
- Organizer
  XXIII World Congress of Neurology（WCN2017）
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Astroglial and Oligodendroglial Connexins Differentially Influence Both Acute and Chronic Progressive Experimental Autoimmune Encephalomyelitis "2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Hiroo Yamaguchi
- Organizer
  The 4th MS summer college 2017
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Neonatal allergen exposure induces autistic-like behavior via hippocampal synaptopathy in mice2017
- Author(s)
  Ban-yu Saitoh, Daan Van Kruining, Claudia Thomsen, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Astroglial and oligodendroglial connexins differentially modulate acute and chronic experimental autoimmune encephalomyelitis2017
- Author(s)
  Ryo Yamasaki, Mei Fang, Yinan Zhao, Hayato Une, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  The 22nd Annual Meeting of the Japan Glia
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Oligodendroglia-specific Connexin 47 deletion induced relapse-remitting EAE model mice.2017
- Author(s)
  Ryo Yamasaki, Yinan Zhao, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  the 10th Congress of the Pan-Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] T-05-040C Astrocytic connexin 30 deletion leads to hypersensitivity in a MPTP mouse model of Parkinson’s disease2017
- Author(s)
  Atsushi Fujita, MD,1 Hiroo Yamaguchi, MD, PhD,1 Ryo Yamasaki, MD, PhD,1 Yuta Matsuoka, PhD,2 Ken-ichi Yamada, PhD,2 Jun-ichi Kira, MD, PhD
- Organizer
  Euroglia2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Experimental autoimmune encephalomyelitis is ameliorated in mice with gray matter astroglia-specific inducible connexin 43 knock-out2017
- Author(s)
  "Hayato Une, Hiroo Yamaguchi, Yinan Zhao, Koji Shinoda, Katsuhisa Masaki, Magdalena Gotz, Ryo Yamasaki, and Jun-ichi Kira "
- Organizer
  XXIII World Congress of Neurology（WCN2017）
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Astroglial (Cx30, Cx43) and oligodendroglial (Cx47) connexins modulate acute and chronic experimental autoimmune encephalomyelitis (EAE) "2017
- Author(s)
  "Ryo Yamasaki, Fang Mei, Hayato Une, Zhao Yinan, Hiroo Yamaguchi, Jun-ichi Kira "
- Organizer
  The 4th MS summer college 2017
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Astroglial and Oligodendroglial Connexins Differentially Influence Both Acute and Chronic Progressive Experimental Autoimmune Encephalomyelitis.2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Hiroo Yamaguchi
- Organizer
  International Gap Junction Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Oligodendroglial Cx47 mediates myelin protective effects and plays a role in suppressing infiltration of inflammatory cells in autoimmune encephalomyelitis.2017
- Author(s)
  Yinan Zhao, Ryo Yamasaki, Hiroo Yamaguchi, Hayato Une, Yiwen Cui, Jun-ichi Kira
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Astroglial and oligodendroglial connexins differentially modulate acute and chronic experimental autoimmune encephalomyelitis.2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Kyoko Iinuma, Katsuhisa Masaki, Koji Shinoda, Hiroo Yamaguchi
- Organizer
  The 142nd American Neurological Association Annual Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] 筋萎縮性側索硬化症モデルマウスにおいてCCR2陽性末梢免疫細胞は病態保護的に働く2017
- Author(s)
  白石　渉、山﨑　亮、吉良潤一
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09342
[Presentation] Elucidation of pathomechanistic effect toward central nervous system (CNS) demyelinating disorders by altered function of gap junction-consisting protein “connexins”2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Kyoko Iinuma, Katsuhisa Masaki, Koji Shinoda, Hiroo Yamaguchi.
- Organizer
  グリアアセンブリ第5回冬のシンポジウム
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] 視神経脊髄炎脳病巣の神経病理学的検討：大脳皮質の炎症細胞浸潤と脱髄を伴う限局性アストロサイトパチー2017
- Author(s)
  林田翔太郎, 眞﨑勝久, 鈴木諭, 松下拓也, 山﨑亮, 末長敏彦, 高橋和也, 岩城徹, 吉良潤一
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] "Astroglial and oligodendroglial connexins differentially modulate acute and chronic experimental autoimmune encephalomyelitis"2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Kyoko Iinuma, Katsuhisa Masaki, Koji Shinoda, Hiroo Yamaguchi
- Organizer
  the 142nd American Neurological Association Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Oligodendroglial Cx47 mediates myelin protective effects and plays a role in suppressing infiltration of inflammatory cells in autoimmune encephalomyelitis2017
- Author(s)
  "Yinan Zhao, Ryo Yamasaki, Hiroo Yamaguchi, Hayato Une, Yiwen Cui, Jun-ichi Kira "
- Organizer
  The 29th Annual Meeting of the Japanese Society Neuroimmunology
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Focal cortical astrocytopathy lesions with demyelination and inflammatory cell infiltrates in neuromyelitis optica spectrum disorder: a neuropathological study of eleven autopsied cases.2017
- Author(s)
  Shotaro Hayashida, Katsuhisa Masaki, Satoshi O. Suzuki, Takuya Matsushita, Ryo Yamasaki, Toshihiko Suenaga, Kazuya Takahashi, Toru Iwaki, Jun-ichi Kira
- Organizer
  7th Joint ECTRIMS-ACTRIMS Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] "Oligodendroglia-specific Connexin 47 deletion induced relapse-remitting EAE model mice"2017
- Author(s)
  "Ryo Yamasaki MD, PhD, Yinan Zhao MD, Hiroo Yamaguchi MD, PhD, Jun-ichi Kira MD, PhD "
- Organizer
  "10th PACTRIMS Ho Chi Minh City, Vietｎam"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Astroglial (Cx30, Cx43) and oligodendroglial (Cx47) connexins modulate acute and chronic experimental autoimmune encephalomyelitis (EAE) "2017
- Author(s)
  "Ryo Yamasaki, Fang Mei, Hayato Une, Zhao Yinan, Hiroo Yamaguchi, Jun-ichi Kira "
- Organizer
  The 4th MS summer college 2017
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Connexin 30 欠損マウスにおける慢性進行期EAEの軽症化2017
- Author(s)
  "山﨑　亮、方　梅、李　広瑞、藤田篤史、宇根隼人、山口浩雄、吉良潤一 "
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Deviated Repertoire of γδ T Cells is Associated with Disease Severity of Multiple Sclerosis.2017
- Author(s)
  Maimaitijiang Guzailiayi、Shinoda Koji、Nakamura Yuri、Matsushita Takuya、Yamasaki Ryo、Yoshikai Yasunobu、Kira Jun-ichi
- Organizer
  10th Congress of the Pan-Asian-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (PACTRIMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09341
[Presentation] 世界初の肥厚性硬膜炎動物モデル作成とTGF-βシグナルを標的とした新規治療法開発2017
- Author(s)
  崔訳文、眞﨑勝久、山﨑亮、林田翔太郎、山口浩雄、兵藤文紀、江藤比奈子、米川智、松下拓也、吉田眞理、Malie Malissen 、Bernard Malissen 、吉良潤一
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K19663
[Presentation] Experimental autoimmune encephalomyelitis is ameliorated in mice with gray matter astroglia-specific inducible connexin 43 knock-out.2017
- Author(s)
  Hayato Une, Hiroo Yamaguchi, Yinan Zhao, Koji Shinoda, Katsuhisa Masaki, Magdalena Götz, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  XXIII World Congress of Neurology (WCN2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] γδ型Ｔ細胞のレパトワ偏倚は多発性硬化症の臨床的障害度に関連する2017
- Author(s)
  篠田絋司, グザリアイ・ママティジャン, 中村優理, 眞﨑勝久, 松下拓也, 山﨑亮, 吉開泰信, 吉良潤一
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] 末梢のアレルギー素因に伴う中枢神経グリア細胞の活性化と神経因性疼痛2017
- Author(s)
  山崎　亮
- Organizer
  第16回　痛みの研究会
- Place of Presentation
  福岡
- Year and Date
  2017-02-20
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Astroglial and Oligodendroglial Connexins Differentially Influence Both Acute and Chronic Progressive Experimental Autoimmune Encephalomyelitis "2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Hiroo Yamaguchi
- Organizer
  "International Gap Junction Conference Glasgow 2017 "
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Astroglial connexin 30 deletion leads to hypersensitivity in a MPTP mouse model of Parkinson’s disease2017
- Author(s)
  Atsushi Fujita, 〇Hiroo Yamaguchi, Ryo Yamasaki, Yuta Matsuoka, Ken-ichi Yamada, Jun-ichi Kira
- Organizer
  XXIII World Congress of Neurology（WCN2017）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Derangement of γδ T cell subsets is associated with disease severity of multiple sclerosis.2017
- Author(s)
  Maimaitijiang Guzailiayi, Koji Shinoda, Yuri Nakamura, Katsuhisa Masaki, Takuya Matsushita, Ryo Yamasaki, Yasunobu Yoshikai, Jun-ichi Kira
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Astroglial and oligodendroglial connexins differentially modulate acute and chronic experimental autoimmune encephalomyelitis2017
- Author(s)
  Ryo Yamasaki, Mei Fang, Yinan Zhao, Hayato Une, Hiroo Yamaguchi, Jun-ichi Kira
- Organizer
  The 22nd Annual Meeting of the Japan Glia
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Oligodendroglia-specific Connexin 47 deletion induced relapse-remitting EAE model mice"2017
- Author(s)
  "Ryo Yamasaki MD, PhD, Yinan Zhao, MD, Hiroo Yamaguchi MD, PhD, Jun-ichi Kira MD, PhD."
- Organizer
  "10th PACTRIMS Ho Chi Minh City, Vietｎam"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] "Oligodendroglia-specific Connexin 47 deletion induced relapse-remitting EAE model mice"2017
- Author(s)
  "Ryo Yamasaki MD, PhD, Yinan Zhao, MD, Hiroo Yamaguchi MD, PhD, Jun-ichi Kira MD, PhD."
- Organizer
  "10th PACTRIMS Ho Chi Minh City, Vietｎam"
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Elucidation of pathophysiology of glial dysfunction in neurological/psychiatric disorders2017
- Author(s)
  Kira J, Watanabe M, Yamasaki R, Matsushita T, Yamaguchi H, Masaki K, Fujita A, Une H, Fang M, Fujii T, Hayashida S, Saitoh BY, Shiraishi W, Tyou E, Camelia UI
- Organizer
  Glial disorders
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Astroglial and Oligodendroglial Connexins Differentially Influence Both Acute and Chronic Progressive Experimental Autoimmune Encephalomyelitis "2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Hiroo Yamaguchi
- Organizer
  "International Gap Junction Conference Glasgow 2017 "
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] "Astroglial and oligodendroglial connexins differentially modulate acute and chronic experimental autoimmune encephalomyelitis"2017
- Author(s)
  Jun-ichi Kira, Ryo Yamasaki, Hayato Une, Mei Fang, Yinan Zhao, Guangrui Li, Kyoko Iinuma, Katsuhisa Masaki, Koji Shinoda, Hiroo Yamaguchi
- Organizer
  the 142nd American Neurological Association Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] A Distinct Repertoire of γδ T cell Population is Associated with Disease Severity of Multiple Sclerosis.2017
- Author(s)
  Koji Shinoda, Maimaitijiang Guzailiayi, Yuri Nakamura, Katsuhisa Masaki, Takuya Matsushita, Ryo Yamasaki, Yasunobu Yoshikai, Jun-ichi Kira
- Organizer
  7th Joint ECTRIMS-ACTRIMS Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Connexin 30 欠損マウスにおける慢性進行期EAEの軽症化2017
- Author(s)
  山﨑亮, 方梅, 李広瑞, 藤田篤史, 宇根隼人, 山口浩雄, 吉良潤一
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Astroglial connexin 30 deletion leads to hypersensitivity in a MPTP mouse model of Parkinson’s disease2017
- Author(s)
  Atsushi Fujita, 〇Hiroo Yamaguchi, Ryo Yamasaki, Yuko Kobayakawa,Yuta Matsuoka,Ken-ichi Yamada,Jun-ichi Kira
- Organizer
  Neuroscience 2017
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Oligodendroglial Cx47 mediates myelin protective effects and plays a role in suppressing infiltration of inflammatory cells in autoimmune encephalomyelitis2017
- Author(s)
  "Yinan Zhao, Ryo Yamasaki, Hiroo Yamaguchi, Hayato Une, Yiwen Cui, Jun-ichi Kira "
- Organizer
  The 29th Annual Meeting of the Japanese Society Neuroimmunology
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Elucidation of pathophysiology of glial dysfunction in neurological/psychiatric disorders.2017
- Author(s)
  Jun-ichi Kira, Mitsuru Watanabe, Ryo Yamasaki, Takuya Matsushita, Hiroo Yamaguchi, Katsuhisa Masaki, Atsushi Fujita, Hayato Une, Mei Fang, Takayuki Fujii, Shintaro Hayashida, Ban-yu Saitoh, Wataru Shiraishi, Yinan Zhao, Ulfa Camelia Indiasari
- Organizer
  Glial disorders
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] "EARLY POSTNATAL ALLERGEN EXPOSURE INDUCES AUTISM-LIKE BEHAVIOR IN MALE MICE "2017
- Author(s)
  Ban-yu Saitoh, Daan Van Kruining, Claudia Thomsen, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  XXIII World Congress of Neurology（WCN2017）
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Connexin 30 欠損マウスにおける慢性進行期EAEの軽症化2017
- Author(s)
  "山﨑　亮、方　梅、李　広瑞、藤田篤史、宇根隼人、山口浩雄、吉良潤一 "
- Organizer
  第29回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] コネキシン30欠損マウスにおける慢性進行期EAEの軽症化-治療標的としてのCx30の意義-2017
- Author(s)
  山崎　亮
- Organizer
  平成28年度エビデンス班会議
- Place of Presentation
  東京
- Year and Date
  2017-01-18
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Atopic disease model mice express more severe signs at the chronic phase of EAE.2016
- Author(s)
  山崎　亮
- Organizer
  第57回日本神経学会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25461282
[Presentation] Early- and late-activated microglia show distinct localization and exert different impact on TDP-43 pathology in amyotrophic lateral sclerosis spinal cord (oral communication)2016
- Author(s)
  Shintaro Hayashi, Ryo Yamasaki, et al.
- Organizer
  27th International Symposium on ALS/MND
- Place of Presentation
  The Convention Center Dublin (Ireland)
- Year and Date
  2016-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] Th1 cells inhibit the expression of connexin 43 in astrocytes via microglial activation2016
- Author(s)
  Mitsuru Watanabe, Katsuhisa Masaki, Ryo Yamasaki, Jun Kawanokuchi, Hideyuki Takeuchi, Takuya Matsushita, Akio Suzumura, Jun-ichi Kira
- Organizer
  グリアアセンブリ第3回夏のワークショップ
- Place of Presentation
  山形
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Experimental autoimmune encephalomyelitis in mice with induced conditional connexin 43 knock-out (Cx43cKO)2016
- Author(s)
  Hayato Une ,Hiroo Yamaguchi, Yinan Zhao,Koji Shinoda,Katsuhisa Masaki, Magdalena Gotz ,Ryo Yamasaki, Jun-ichi Kira
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Experimental Autoimmune Encephalomyelitis (EAE) is Ameliorated in Mice with Gray Matter (GM) Astrocyte- Specific Inducible Conditional Connexin 43 Knock-Out (Cx43cKO)2016
- Author(s)
  Hayato Une, Hiroo Yamaguchi, Yinan Zhao, Koji Shinoda, Katsuhisa Masaki, Magdalena Gotz, Ryo Yamasaki, and Jun- ichi Kira
- Organizer
  9th Congress of the Pan-Asian Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Early and Extensive Spinal White Matter Pathologyin Neuromyelitis Optica2016
- Author(s)
  Shintaro Hayashi, Ryo Yamasaki, Hiroyuki Murai,Koichi Okamoto, Jun-ichi Kira
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Functional analysis of connexin30 in experimental autoimmune encephalomyelitis2016
- Author(s)
  山崎　亮
- Organizer
  ANA annual meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09694
[Presentation] Th1 cells inhibit the expression of connexins in astrocytes2016
- Author(s)
  Mitsuru Watanabe, Katsuhisa Masaki, Ryo Yamasaki, Jun Kawanokuchi, Hideyuki Takeuchi, Akio Suzumura, Jun-ichi Kira
- Organizer
  32ND CONGRESS OF THE EUROPEAN COMMITTEE FOR TREATMENT AND RESEARCH IN MULTIPLE SCLEROSIS
- Place of Presentation
  London, UK
- Year and Date
  2016-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Distinct Repertoires of CD4 and CD8 T Cells in Multiple Sclerosis Patients with and without Deletion-type Copy Number Variations2016
- Author(s)
  Guzailiayi Maimaitijiang, Koji Shinoda, Yuri Nakamura, Katsuhisa Masaki, Takuya Matsushita, Ryo Yamasaki, Yasunobu Yoshikai, Jun-ichi Kira
- Organizer
  9th Congress of the Pan-Asian Committee for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  Bangkok, Thailand
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] Splenectomy might ameliorate disease progression in ALS mouse model2016
- Author(s)
  白石　渉、山﨑　亮、他
- Organizer
  グリア研究会
- Place of Presentation
  大阪
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] Early- and late-activated microglia show distinct localizations in amyotrophic lateral sclerosis spinal cord2016
- Author(s)
  林　信太郎、山﨑　亮、他
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸コンベンションセンター, 神戸ポートピアホテル
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] Clinical and immunological analysis of multiple sclerosis with deletion type of copy-number variation2016
- Author(s)
  Guzailiayi Maimaitijiang, Koji Shinoda, Yuri Nakamura, Song Zi ye Takuya Matsushita, Ryo Yamasaki, Jun-ichi Kira
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-16H02657
[Presentation] 筋萎縮性側索硬化症の脊髄では活性早期ミクログリアは灰白質に、活性後期ミクログリアは白質に分布する2016
- Author(s)
  林　信太郎、山﨑　亮、他
- Organizer
  第28回日本神経面計学会学術集会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K09721
[Presentation] Th1細胞によるアストロサイトのコネキシン発現抑制作用2015
- Author(s)
  山崎　亮、吉良　潤一
- Organizer
  第27回日本神経免疫学会
- Place of Presentation
  岐阜
- Year and Date
  2015-09-15
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Granulocyte-colony stimulating factor protects neurons through the activation of microglia in the mutant superoxide dismutase 1 transgenic ALS model mice2009
- Author(s)
  山崎亮
- Organizer
  134th Annual Meeting of the American Neurological Association
- Place of Presentation
  Baltimore, MD
- Year and Date
  2009-10-13
- Data Source
  KAKENHI-PROJECT-21591088
[Presentation] 変異SOD1トランスジェニックマウスにおけるミクログリア機能障害2009
- Author(s)
  山崎亮
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21591088
[Presentation] G-CSF PROTECTS NEURONS THROUGH THE ACTIVATION OF MICROGLIAIN THE MUTANT SOD1 TRANSGENIC ALS MODEL MICE2009
- Author(s)
  山崎亮
- Organizer
  The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
- Place of Presentation
  BUSAN, Koria
- Year and Date
  2009-08-25
- Data Source
  KAKENHI-PROJECT-21591088
[Presentation] 変異SOD1トランスジェニックマウスにおける末梢神経障害とミクログリアの反応2009
- Author(s)
  山崎亮
- Organizer
  第20回日本末梢神経学会学術集会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591088
[Presentation] Neuropathological Study of Glucose and Lactate Transporters in Demyelinating Disorders
- Author(s)
  Masaki K, Suzuki SO Yamasaki R, Une H, Watanabe M, Sato S, Iwaki T, Kira J
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Atopic inflammation induces microglial activation and tactile allodynia.
- Author(s)
  Yamasaki　R, Wang　B, Fujii T, Kido M, Tsuda M, Inoue K, Kira J
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  神奈川
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Allodynia and microglial activation induced by peripheral atopic diathesis
- Author(s)
  Wang B, Yamasaki R, Kido M, Masaki K, Kira J
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] 気管支喘息モデルマウスはミクログリア活性化とアロディニアを生じる
- Author(s)
  山﨑亮、王氷、藤井敬之、城戸瑞穂、津田誠、井上和秀、吉良潤一
- Organizer
  第25回日本末梢神経学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-08-29 – 2014-08-30
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Copy number variations in T cell receptor loci are associated with susceptibility to multiple sclerosis and neuromyelitis optica
- Author(s)
  Sato S, Yamamoto K, Matsushita T, Isobe N, Kawano Y, Iinuma K, Watanabe M, Yonekawa T, Masaki K, Yoshimura S, Yamasaki R, Kira J
- Organizer
  12th International Congress of Neuroimmunology
- Place of Presentation
  Germany
- Year and Date
  2014-11-09 – 2014-11-13
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Modulation of experimental autoimmune encephalomyelitis in an atopic diathesis animal model
- Author(s)
  Fang M, Yamasaki R, Wang B, Kido M, Kira J
- Organizer
  第26回日本神経免疫学会
- Place of Presentation
  石川
- Year and Date
  2014-09-04 – 2014-09-06
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Atopic inflammation induces microglial activation and tactile allodynia
- Author(s)
  Yamasaki R, Wang B, Fang M, Fujii T, Kido M, Kira J
- Organizer
  CSHL Conference on Glia in Health & Disease
- Place of Presentation
  New York
- Year and Date
  2014-07-17 – 2014-07-21
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Modulation of EAE in an atopic diathesis animal model
- Author(s)
  Fang M, Yamasaki R, Wang B, Kido M, Kira J
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Atopic diathesis model mice express tactile allodynia with glial inflammation in spinal cord
- Author(s)
  Yamasaki R, Wang B, Fujii T, Kido M, Kira J
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] A genome-wide copy number variation study identified T cell receptor as a susceptibility gene for multiple sclerosis and neuromyelitis optica
- Author(s)
  Sato S, Yamamoto K, Matsushita T, Isobe N, Kawano Y, Iinuma K, Watanabe M, Yonekawa T, Masaki K, Yoshimura S, Yamasaki R, Kira J
- Organizer
  2014 Joint ACTRIMS-ECTRIMS Meeting
- Place of Presentation
  Boston, USA
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Neuropathological Study of Glucose and Lactate Transporters in Demyelinating Disorders
- Author(s)
  Masaki K, Suzuki SO, Yamasaki R, Watanabe M, Iwaki T, Kira J
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会　合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model
- Author(s)
  Cui YW, Masaki K, Yamasaki R, Imamura S, Suzuki SO, Hayashi S, Sato S, Nagara Y, Kawamura FM, Kira J
- Organizer
  第55回日本神経学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PLANNED-25117012
[Presentation] 炎症性脱髄病巣におけるミクログリアの役割
- Author(s)
  山崎　亮
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-25461282

1. Masaki Katsuhisa (90612903)

# of Collaborated Projects: 14 results

# of Collaborated Products: 97 results
2. Kira Jun-ichi (40183305)

# of Collaborated Projects: 12 results

# of Collaborated Products: 118 results
3. Yamaguchi Hiroo (00701830)

# of Collaborated Projects: 11 results

# of Collaborated Products: 77 results
4. Watanabe Mitsuru (30748009)

# of Collaborated Projects: 11 results

# of Collaborated Products: 7 results
5. Matsushita Takuya (00533001)

# of Collaborated Projects: 9 results

# of Collaborated Products: 34 results
6. Matsuse Dai (70596395)

# of Collaborated Projects: 7 results

# of Collaborated Products: 47 results
7. Hayashi Shintaro (90312876)

# of Collaborated Projects: 5 results

# of Collaborated Products: 29 results
8. Nakamura Yuri (40822375)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
9. 磯部紀子 (60452752)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
10. 小早川優子 (40733788)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
11. Tateishi Takahisa (50423546)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. 篠田紘司 (70747998)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
13. 藤井敬之 (30822481)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
14. Yuji Kawano (20333479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
15. 雑賀徹 (00744880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
16. 緒方英紀 (90778838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
17. 今村友裕 (30725122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
18. Maimaitijiang Guzailiayi (60887107)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
19. Ohyagi Yasumasa (30301336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. Asai Hirohide (50510210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. Hiwatashi Akio (30444855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. 栄信孝 (80423523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 飯沼今日子 (20380644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 吉村怜 (20596390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 山本健 (60274528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 栂尾理 (10452749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. 山下孝二 (80546565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
28. 本田浩 (90145433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. 萬谷博 (20321870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 海田賢一 (40531190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
31. 立川正憲 (00401810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 迫田礼子 (70972230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 米満吉和 (40315065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 原田結 (00608507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 諸富洋介 (60645365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 扇谷昌宏 (60636455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 加藤隆弘 (70546465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 松本省二 (00570772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. KAWACHI Izumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. MOTOMURA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. KAWAMURA Nobutoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 松岡悠太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 大篭友博

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Yamasaki Ryou 山崎 亮

Yamasaki Ryo 山崎 亮

山崎 亮 ヤマサキ リヨウ

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Misfold protein removal therapy with CCR2-positive cells from peripheral nerves in motor neuron diseasePrincipal Investigator

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Yamasaki Ryou 山崎亮

Yamasaki Ryo 山崎亮

山崎亮ヤマサキリヨウ