Adachi Makoto 足立誠

… Alternative Names

ADACHI Makoto 足立誠

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Researcher Number	10468192
Other IDs	https://orcid.org/0000-0002-9382-7052
Affiliation (Current)	2024: 名古屋市立大学, 医薬学総合研究院(医学), 研究員
Affiliation (based on the past Project Information) *help	2023: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2015 – 2020: 朝日大学, 歯学部, 講師 2014: 横浜市立大学, 医学(系)研究科(研究院), その他 2013 – 2014: 横浜市立大学, 医学(系)研究科(研究院), 客員研究員 2010 – 2011: 横浜市立大学, 附属病院, 指導診療医 2009: 横浜市立大学, 附属病院, 常勤診療医 2008: 横浜市立大学, 附属病院, 特別職診療医
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Pathobiological dentistry/Dental radiology Except Principal Investigator Pathobiological dentistry/Dental radiology / Otorhinolaryngology / Surgical dentistry / Radiation science
Keywords	Principal Investigator 免疫チェックポイント阻害薬 / シスプラチン / 腫瘍免疫改変メカニズム / 低酸素環境 / 頭頸部扁平上皮がん / がん幹細胞 / 口腔がん / 上皮間葉移行 / EMT / 低酸素 … More Except Principal Investigator … More 低酸素 / 放射線 / 薬剤耐性 / がん幹細胞 / 口腔がん / 腫瘍内浸潤マクロファージ / 骨髄由来免疫抑制細胞 / 腫瘍関連マクロファージ / 腫瘍免疫 / 遺伝子 / 癌 / 幹細胞 / HIF-1a / CD44 / 唾液腺癌 / サイトカイン / T細胞 / 免疫 / 腫瘍 / HIF-1α / 低酸素状態 / 耳下腺がん / HIF-1 / 悪性化 / 唾液腺がん / CD34陽性細胞 / 末梢血 / 三次元X線CT / 培養骨膜 / ゼラチンスポンジ / 自家培養骨膜 / 骨髄間質細胞 / G-CSF / CD34 / 骨再生 / Immunoblot / RT-PCR / コロニー形成法 / scrape loading assay / lindane / ギャップ結合阻害 / メカニズム / 放射線感受性 / 3次元培養細胞 / 抵抗性 / ギャップ結合 / 培養細胞 / がん Less

口腔扁平上皮がんの薬剤耐性獲得に伴う腫瘍免疫改変メカニズムの解明Principal Investigator
- Principal Investigator
  
  足立誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagoya City University
Characters of stem cells from salivary carcinoma cells
- Principal Investigator
  
  Ijichi Kei
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
Clarification of metastasis development mechanism in oral cancer stem cell
- Principal Investigator
  
  Umemura Naoki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Asahi University
低酸素環境下における口腔癌のがん幹細胞に対する新規分子標的治療の開発Principal Investigator
- Principal Investigator
  
  足立誠
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Asahi University
Antitumor immunities with low dose / low dose rate radiation on murine model with oral squamous cell carcinoma
- Principal Investigator
  
  Takayama Eiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Asahi University
Metastasis and invasion mechanism in the hypoxia environment of parotid gland cancer
- Principal Investigator
  
  IJICHI Kei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya City University
Analysis of oral cancer microenvironment and invasionPrincipal Investigator
- Principal Investigator
  
  ADACHI Makoto
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Yokohama City University
Effect of Concomitant use of G-CSF in bone regeneration by CD34 positive cells.
- Principal Investigator
  
  OHTA Shinsuke
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Yokohama City University
Elucidation of the mechanism for radioresistance from the viewpoint of gap junction using 3D-cultured cancer cells
- Principal Investigator
  
  TORIGOE Soichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University

All 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Gene expression analyses associated with malignant phenotypes of metastatic sub-clones derived from a mouse oral squamous cell carcinoma Sq-1979 cell line2018
- Author(s)
  Adachi Mitsutaka、Mizuno?Kamiya Masako、Takayama Eiji、Kawaki Harumi、Inagaki Toshihiro、Sumi Shigeki、Motohashi Masayuki、Muramatsu Yasunori、Sumitomo Shin?Ichiro、Shikimori Michio、Yamazaki Yutaka、Kondoh Nobuo
- Journal Title
  
  Oncology Letters
  
  Volume: 15 Pages: 3350-3356
- DOI
  10.3892/ol.2017.7648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11096, KAKENHI-PROJECT-15K11331, KAKENHI-PROJECT-18K08872, KAKENHI-PROJECT-18K09780
[Journal Article] The luminance ratio of autofluorescence in a xenograft mouse model is stable through tumor growth stages.2018
- Author(s)
  Sumi S, Umemura N, Adachi M, Ohta T, Naganawa K, Kawaki H, Takayama E, Kondoh N, Sumitomo S.
- Journal Title
  
  Clinical nad experimental dental research
  
  Volume: 4(5) Issue: 5 Pages: 174-181
- DOI
  10.1002/cre2.126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11691, KAKENHI-PROJECT-17K11817, KAKENHI-PROJECT-17K11891, KAKENHI-PROJECT-18K09780, KAKENHI-PROJECT-17K17146, KAKENHI-PROJECT-17K11890
[Journal Article] Management consideration for patient with a large solitary fibrous tumor occupying the infratemporal fossa: A case report.2018
- Author(s)
  Adachi M, Motohashi M, Kaku Y, Sugie S, Muramatsu Y, Sumitomo S
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 8 Pages: 549-552
- DOI
  10.3892/mco.2018.1575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11890
[Journal Article] Orofacial Pain Associated with Vasospastic Angina: A Case Report2017
- Author(s)
  Adachi Makoto、Hayashi Mio、Segawa Tomonori、Yamaki Takahiko、Muramatsu Yasunori、Sumitomo Shinichiro
- Journal Title
  
  J Oral Facial Pain Headache
  
  Volume: 31 Issue: 4 Pages: e1-e3
- DOI
  10.11607/ofph.1768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11890
[Journal Article] Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells2017
- Author(s)
  Shigeki Sumi, Naoki Umemura, Eiji Takayama, Emika Ohkoshi, Makoto Adachi, Masako Mizuno-Kamiya, Toshihiro Inagaki, Harumi Kawaki, Shinichiro Sumitomo and Nobuo Kondoh
- Journal Title
  
  ONCOLOGY REPORTS
  
  Volume: 37 Issue: 5 Pages: 2897-2904
- DOI
  10.3892/or.2017.5575
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462854, KAKENHI-PROJECT-26463055, KAKENHI-PROJECT-15K11096, KAKENHI-PROJECT-15K11331, KAKENHI-PROJECT-17K11890
[Journal Article] Gene expression analyses associated with malignant phenotypes of metastatic subclones derived from a mouse oral squamous cell carcinoma cell line, Sq-1979.2017
- Author(s)
  Adachi M, Mizuno-Kamiya M, Takayama E, Kawaki H, Umemura N, Inagaki T, Sumi S, Motohashi M, Muramatsu Y, Sumitomo S, Shikimori M, Yamazaki Y, Kondoh N.
- Journal Title
  
  Oncology Letters, 印刷中.
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11096
[Journal Article] Promotion of Nickel (Ni) allergy by anamnestic sensitization with a bacterial component, lipopolysaccharide (LPS), in Mice2016
- Author(s)
  Adachi N, Takayama E, Adachi M, Mizuno-Kamiya M, Kawaki H, Takeuchi H, Kubo S, Ishigami H, Kurachi M, Kondoh N.
- Journal Title
  
  The Open Dentistry Journal
  
  Volume: 10 Issue: 1 Pages: 531-537
- DOI
  10.2174/1874210601610010531
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462984, KAKENHI-PROJECT-26463055, KAKENHI-PROJECT-15K11096
[Presentation] 若年男性に発症したシェーグレン症候群の1例2018
- Author(s)
  原田尚武、足立誠、飯田幸弘、住友伸一郎
- Organizer
  第72回NPO法人　日本口腔科学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11890
[Presentation] Juvenile Sjogren’s syndrome.2018
- Author(s)
  Adachi M, Iida Y, Sumitomo S
- Organizer
  The 30th Annual Congress of Taiwanese Association of Oral and Maxillofacial Surgeons
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11890
[Presentation] 口腔がん診断の自然蛍光画像診断の輝度比率は腫瘍の増大に影響せず安定してる2018
- Author(s)
  鷲見成紀、梅村直己、足立誠、太田貴久、長縄綱亮、川木晴美、高山英次、近藤信夫、住友伸一郎
- Organizer
  第60回歯科基礎医学会学術総会（九州大学）
- Data Source
  KAKENHI-PROJECT-17K11691
[Presentation] Orofacial pain associated with vasospastic angina.2017
- Author(s)
  Adachi M.
- Organizer
  63rd Tri-service Dental Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11890
[Presentation] New strategy for benign parotid surgery.2017
- Author(s)
  Adachi M, Ijichi K, Ehara Y, Takai Y, Sumitomo S
- Organizer
  23rd International Conference on Oral & Maxillofacial Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11890
[Presentation] 口腔扁平上皮癌における口腔粘膜観察装置の解明2017
- Author(s)
  鷲見茂紀、梅村直己、長縄鋼亮、村木智則、足立誠、江原雄一、太田貴久、住友伸一郎
- Organizer
  第62回（公社）日本口腔外科学会総会・学術大会（京都）
- Data Source
  KAKENHI-PROJECT-17K11691
[Presentation] マウス口腔扁平上皮癌細胞株(Sq1979)のリンパ節転移巣由来サブクローン(L 細胞)による Th1 型免疫反応の促進；その制御因子の同定と機能解析2015
- Author(s)
  足立充隆，神谷真子，川木晴美, 高山英次，稲垣俊弘，伊藤宏衣，鷲見成紀，村松泰徳，住友伸一郎，近藤信夫.
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11096
[Presentation] マウス口腔扁平上皮癌の悪性形質獲得に伴う脾細胞の抗腫瘍免疫応答の変化2015
- Author(s)
  鷲見成紀，神谷真子，川木晴美，高山英次，伊藤宏衣，足立充隆，稲垣俊弘，村松泰徳，住友伸一郎，近藤信夫
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11096
[Presentation] マウス口腔扁平上皮癌の悪性化にともなう脾細胞のサイトカイン産生能の改変機構2015
- Author(s)
  稲垣俊弘，神谷真子，川木晴美，髙山英次，伊藤宏衣，鷲見成紀，足立充隆，住友伸一郎，村松泰徳，近藤信夫.
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11096
[Presentation] マウス口腔扁平上皮癌細胞株(Sq1979)の液性因子による間葉系細胞(10T1/2)を介した c-c motif chemokine 2（Ccl2）発現の誘導2015
- Author(s)
  伊藤宏衣，足立充隆，神谷真子，川木晴美, 高山英次，稲垣俊弘，鷲見成紀，村松泰徳，住友伸一郎，近藤信夫.
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K11096

1. Umemura Naoki (80609107)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. IJICHI Kei (50510278)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. MITSUDOU Kenji (70303641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OHTA Shinsuke (30336581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Takayama Eiji (70533446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 近藤信夫 (40202072)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
7. 大越絵実加 (10287667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. TORIGOE Soichiro (20264658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. CHIKUMARU Hiroshi (80217231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOHNAI Iwai (50172127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MATSUI Yoshiro (10181687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 一戸辰夫 (80314219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐藤あやの (40303002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 増田潤子 (20424674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 川木晴美 (70513670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
16. 神谷真子 (80181907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
17. 中田隆博 (40273932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 本庶仁子 (80614106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 江崎伸一 (20620983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 渋谷恭之 (90335430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Kondo Yuzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Adachi Makoto 足立 誠

ADACHI Makoto 足立 誠

Research Projects

Research Products

Co-Researchers

口腔扁平上皮がんの薬剤耐性獲得に伴う腫瘍免疫改変メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characters of stem cells from salivary carcinoma cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of metastasis development mechanism in oral cancer stem cell

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低酸素環境下における口腔癌のがん幹細胞に対する新規分子標的治療の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Antitumor immunities with low dose / low dose rate radiation on murine model with oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metastasis and invasion mechanism in the hypoxia environment of parotid gland cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of oral cancer microenvironment and invasionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of Concomitant use of G-CSF in bone regeneration by CD34 positive cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism for radioresistance from the viewpoint of gap junction using 3D-cultured cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gene expression analyses associated with malignant phenotypes of metastatic sub-clones derived from a mouse oral squamous cell carcinoma Sq-1979 cell line2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The luminance ratio of autofluorescence in a xenograft mouse model is stable through tumor growth stages.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Management consideration for patient with a large solitary fibrous tumor occupying the infratemporal fossa: A case report.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Orofacial Pain Associated with Vasospastic Angina: A Case Report2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metastasized murine oral squamous cell carcinoma cells induce intratumoral polymorphonuclear myeloid derived suppressor cells2017

Adachi Makoto 足立誠

ADACHI Makoto 足立誠