ASANO KENICHI 浅野謙一

… Alternative Names

ASANO Kenichi 浅野謙一

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Researcher Number	10513400
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 横浜市立大学, 医学研究科, 教授 2013 – 2024: 東京薬科大学, 生命科学部, 准教授 2011: 東京薬科大学, 生命科学部, 准教授 2009 – 2010: The Institute of Physical and Chemical Research, 自然免疫研究チーム, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry / Transformative Research Areas, Section (III) / Biological Sciences / Experimental pathology Except Principal Investigator Transformative Research Areas, Section (III) / Basic Section 49020:Human pathology-related / Biological Sciences / Human pathology / Experimental pathology
Keywords	Principal Investigator マクロファージ / CD169 / 炎症性腸疾患 / 単球 / CCL8 / 分化 / 死細胞 / 制御性単球 / Ym1 / 非アルコール性脂肪肝炎 … More / 線維化 / 肝臓 / 長鎖脂肪酸 / 肝線維症 / EGR2 / 代謝障害関連脂肪肝炎 / MASH / 炎症収束 / がん / 炎症制御 / 組織修復 / 自然免疫 / 炎症 / 腸炎 / 大腸炎 / 細胞死 / 腸管免疫 / hnRNP / ビメンチン / DAMPs / シアロアドヘジン / 抗体医薬 / 発生・分化 / CD169/Siglec-1 / 転写因子 / 貪食 / 免疫寛容 / クロスプレゼンテーション / リンパ節 / 腫瘍 … More Except Principal Investigator マクロファージ / 細胞死 / がん / 恒常性維持 / 自己認識 / 自己分子 / 免疫センサー / 病理学 / 貪食 / CD169 / CD163 / がん免疫 Less

好中球様単球の誘導機構と腸炎の病態形成における役割の解明Principal Investigator
- Principal Investigator
  
  浅野謙一
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Yokohama City University
Differentiation of non-canonical regulatory monocytes triggered by perturbation in inner selfPrincipal Investigator
- Principal Investigator
  
  浅野謙一
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yokohama City University
  Tokyo University of Pharmacy and Life Science
Self-referential immune perception
- Principal Investigator
  
  山崎晶
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
Development of liver fibrosis by monocyte-derived macrophagesPrincipal Investigator
- Principal Investigator
  
  ASANO Kenichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
The significance of macrophages in anti-cancer immune responses
- Principal Investigator
  
  komohara Yoshihro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kumamoto University
Immune regulation by dead intestinal epithelial cellsPrincipal Investigator
- Principal Investigator
  
  ASANO Kenichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
The significance of macrophages in several diseases
- Principal Investigator
  
  Komohara Yoshihiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kumamoto University
Regulation of Mucosal Immunity by CD169 MacrophagesPrincipal Investigator
- Principal Investigator
  
  ASANO Kenichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Mechanisms of immunoregulation by dead cell clearance
- Principal Investigator
  
  Tanaka Masato
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
CD169陽性マクロファージの分化制御機構の解明Principal Investigator
- Principal Investigator
  
  浅野謙一
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of CD169 macrophages in anti-tumor immunity induced by dead tumor cells
- Principal Investigator
  
  TANAKA Masato
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Clearance of Dead Tumor Cells and Tumor ImmunityPrincipal Investigator
- Principal Investigator
  
  ASANO Kenichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo University of Pharmacy and Life Science
  The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2011 2010

All Journal Article Presentation Book Patent

[Book] Chronic Inflammation2016
- Author(s)
  Kenichi Asano and Masato Tanaka
- Total Pages
  702
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460401
[Journal Article] Dysfunction of sinus macrophages in tumor‐bearing host induces resistance to immunotherapy2023
- Author(s)
  Anami Toshiki、Pan Cheng、Fujiwara Yukio、Komohara Yoshihiro、Yano Hiromu、Saito Yoichi、Sugimoto Masamichi、Wakita Daiko、Motoshima Takanobu、Murakami Yoji、Yatsuda Junji、Takahashi Naofumi、Suzu Shinya、Asano Kenichi、Tamada Koji、Kamba Tomomi
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 1 Pages: 59-69
- DOI
  10.1111/cas.16003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15788, KAKENHI-PROJECT-22K04845, KAKENHI-PROJECT-22K08456, KAKENHI-PROJECT-23K06362, KAKENHI-PROJECT-20H03459
[Journal Article] CD169-positive macrophages enhance abscopal effect of radiofrequency ablation therapy in liver cancer2022
- Author(s)
  Song Xiaojia、Li Na、Liu Yuan、Wang Zehua、Wang Tixiao、Tan Siyu、Li Chunyang、Qiu Chunhong、Gao Lifen、Asano Kenichi、Tanaka Masato、Liang Xiaohong、Liu Xinyong、Ma Chunhong
- Journal Title
  
  Translational Oncology
  
  Volume: 15 Issue: 1 Pages: 101306-101306
- DOI
  10.1016/j.tranon.2021.101306
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H03473
[Journal Article] Synaptic pruning of murine adult-born neurons by microglia depends on phosphatidylserine2022
- Author(s)
  Kurematsu Chihiro、Sawada Masato、Ohmuraya Masaki、他
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 219 Issue: 4
- DOI
  10.1084/jem.20202304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08405, KAKENHI-PROJECT-20K22696, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-21K06395, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H00500, KAKENHI-PROJECT-21K06541
[Journal Article] CD169+ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling2022
- Author(s)
  Camara Abdouramane、Lavanant Alice C.、Abe Jun、Desforges Henri Lee、Alexandre Yannick O.、Girardi Erika、Igamberdieva Zinaida、Asano Kenichi、Tanaka Masato、Hehlgans Thomas、Pfeffer Klaus、Pfeffer Sebastien、Mueller Scott N.、Stein Jens V.、Mueller Christopher G.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 3
- DOI
  10.1073/pnas.2108540119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H03473
[Journal Article] Replication of Influenza A Virus in Secondary Lymphatic Tissue Contributes to Innate Immune Activation2021
- Author(s)
  Friedrich Sarah-Kim、Schmitz Rosa、Bergerhausen Michael、Lang Judith、Duhan Vikas、Hardt Cornelia、Tenbusch Matthias、Prinz Marco、Asano Kenichi、Bhat Hilal、Hamdan Thamer A.、Lang Philipp Alexander、Lang Karl Sebastian
- Journal Title
  
  Pathogens
  
  Volume: 10 Issue: 5 Pages: 622-622
- DOI
  10.3390/pathogens10050622
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06877
[Journal Article] Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis2021
- Author(s)
  Honda Fumika、Tsuboi Hiroto、Ono Yuko、Abe Saori、Takahashi Hiroyuki、Ito Kiyoaki、Yamada Kazunori、Kawano Mitsuhiro、Kondo Yuya、Asano Kenichi、Tanaka Masato、Malissen Marie、Malissen Bernard、Matsumoto Isao、Sumida Takayuki
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 23 Issue: 1 Pages: 214-214
- DOI
  10.1186/s13075-021-02597-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-21H02959, KAKENHI-PROJECT-18K08236, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K08453, KAKENHI-PROJECT-21K08473, KAKENHI-PROJECT-21K08483, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H03473
[Journal Article] Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor2021
- Author(s)
  Shibuya Takumi、Kamiyama Asami、Sawada Hirotaka、Kikuchi Kenta、Maruyama Mayu、Sawado Rie、Ikeda Naoki、Asano Kenichi、Kurotaki Daisuke、Tamura Tomohiko、Yoneda Atsuko、Imada Keisuke、Satoh Takashi、Akira Shizuo、Tanaka Masato、Yotsumoto Satoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 663115-663115
- DOI
  10.3389/fimmu.2021.663115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06563, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H03473, KAKENHI-PROJECT-19K08894
[Journal Article] Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney2021
- Author(s)
  Takahashi Naohiro、Kikuchi Hiroaki、Usui Ayaka、Furusho Taisuke、Fujimaru Takuya、Fujiki Tamami、Yanagi Tomoki、Matsuura Yoshiaki、Asano Kenichi、Yamamoto Kouhei、Ando Fumiaki、Susa Koichiro、Mandai Shintaro、Mori Takayasu、Rai Tatemitsu、Uchida Shinichi、Arita Makoto、Sohara Eisei
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 25 Issue: 5 Pages: 445-455
- DOI
  10.1007/s10157-021-02021-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-19H01049, KAKENHI-PROJECT-19H03556, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K16181, KAKENHI-PROJECT-21K20710, KAKENHI-PROJECT-19H03672
[Journal Article] Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development2020
- Author(s)
  Utz Sebastian G.、See Peter、Mildenberger Wiebke、Thion Morgane Sonia、Silvin Aymeric、Lutz Mirjam、Ingelfinger Florian、Rayan Nirmala Arul、Lelios Iva、Buttgereit Anne、Asano Kenichi、Prabhakar Shyam、Garel Sonia、Becher Burkhard、Ginhoux Florent、Greter Melanie
- Journal Title
  
  Cell
  
  Volume: 181 Issue: 3 Pages: 557-573.e18
- DOI
  10.1016/j.cell.2020.03.021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052
[Journal Article] Usp18 Expression in CD169+ Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV2020
- Author(s)
  Friedrich Sarah-Kim、Schmitz Rosa、Bergerhausen Michael、Lang Judith、Cham Lamin B.、Duhan Vikas、H?ussinger Dieter、Hardt Cornelia、Addo Marylyn、Prinz Marco、Asano Kenichi、Lang Philipp Alexander、Lang Karl Sebastian
- Journal Title
  
  Vaccines
  
  Volume: 8 Issue: 1 Pages: 142-142
- DOI
  10.3390/vaccines8010142
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052
[Journal Article] Maf expression in human macrophages and lymph node sinus macrophages in patients with esophageal cancer2019
- Author(s)
  Takeya Hiroto、Ohnishi Koji、Shiota Takuya、Saito Yoichi、Fujiwara Yukio、Yagi Taisuke、Kiyozumi Yuki、Baba Yoshifumi、Yoshida Naoya、Asano Kenichi、Tanaka Masato、Baba Hideo、Komohara Yoshihiro
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 59 Issue: 3 Pages: 112-118
- DOI
  10.3960/jslrt.19002
- NAID
  130007720030
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07459, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04060
[Journal Article] MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane.2019
- Author(s)
  Miyagawa, T.,* Hasegawa, K.,* Aoki, Y.,* Watanabe, T.,* Otagiri, Y., Arasaki, K., Wakana, Y., Asano, K., Tanaka, M., Yamaguchi, H., Tagaya, M. and Inoue, H. (*, These authors contributed equally to this work.)
- Journal Title
  
  J. Cell Biol.
  
  Volume: 218 Issue: 10 Pages: 3355-3371
- DOI
  10.1083/jcb.201808149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06138, KAKENHI-PROJECT-18K07219, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-18H02656, KAKENHI-PROJECT-17K07348, KAKENHI-PROJECT-17H04068
[Journal Article] Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche2019
- Author(s)
  Camara Abdouramane、Cordeiro Olga G.、Alloush Farouk、Sponsel Janina、Chypre M?lanie、Onder Lucas、Asano Kenichi、Tanaka Masato、Yagita Hideo、Ludewig Burkhard、Flacher Vincent、Mueller Christopher G.
- Journal Title
  
  Immunity
  
  Volume: 50 Issue: 6 Pages: 1467-1481.e6
- DOI
  10.1016/j.immuni.2019.05.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068
[Journal Article] CD169-positive sinus macrophages in the lymph nodes determine bladder cancer prognosis.2018
- Author(s)
  Asano T, Ohnishi K, Shiota T, Motoshima T, Sugiyama Y, Yatsuda J, Kamba T, Ishizaka K, Komohara Y (**).
- Journal Title
  
  Cancer Sci 109;1723-1730, 2018
  
  Volume: 109 Pages: 1723-1723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05162
[Journal Article] CD169 macrophages regulate immune responses toward particulate materials in the circulating fluid.2018
- Author(s)
  Asano K, Kikuchi K, Tanaka M.
- Journal Title
  
  J Biochem
  
  Volume: 164 Issue: 2 Pages: 77-85
- DOI
  10.1093/jb/mvy050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04068
[Journal Article] Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice.2018
- Author(s)
  Deguchi Y, Nishina T, Asano K, Ohmuraya M, Nakagawa Y, Nakagata N, Sakuma T, Yamamoto T, Araki K, Mikami T, Tanaka M, Nakano H.
- Journal Title
  
  Biochemical Biophysical Research Communications
  
  Volume: 505 Issue: 2 Pages: 453-459
- DOI
  10.1016/j.bbrc.2018.09.128
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11242, KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K19533, KAKENHI-PROJECT-17K15626
[Journal Article] Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation2018
- Author(s)
  Kikuchi Kenta、Iida Mayumi、Ikeda Naoki、Moriyama Shigetaka、Hamada Michito、Takahashi Satoru、Kitamura Hiroshi、Watanabe Takashi、Hasegawa Yoshinori、Hase Koji、Fukuhara Takeshi、Sato Hideyo、Kobayashi Eri H.、Suzuki Takafumi、Yamamoto Masayuki、Tanaka Masato、Asano Kenichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 201 Issue: 2 Pages: 635-651
- DOI
  10.4049/jimmunol.1800040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-17K15590
[Journal Article] Emergence of immunoregulatory Ym1+Ly6Chi monocytes during recovery phase of tissue injury2018
- Author(s)
  Ikeda Naoki、Asano Kenichi、Kikuchi Kenta、Uchida Yoshimi、Ikegami Hiroki、Takagi Ryo、Yotsumoto Satoshi、Shibuya Takumi、Makino-Okamura Chieko、Fukuyama Hidehiro、Watanabe Takashi、Ohmuraya Masaki、Araki Kimi、Nishitai Gen、Tanaka Masato
- Journal Title
  
  Science Immunology
  
  Volume: 3 Issue: 28
- DOI
  10.1126/sciimmunol.aat0207
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K09398
[Journal Article] Salt suppresses IFNγ inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells.2017
- Author(s)
  Arai Y, Takahashi D, Asano K, Tanaka M, Oda M, Ko SBH, Ko MSH, Mandai S, Nomura N, Rai T, Uchida S, Sohara E.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 46580-46580
- DOI
  10.1038/srep46580
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-16H05314, KAKENHI-PROJECT-15K14431, KAKENHI-PROJECT-15K15327, KAKENHI-PROJECT-16K15467, KAKENHI-PROJECT-16K09642, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-15H04812, KAKENHI-PROJECT-17H04068
[Journal Article] CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis2017
- Author(s)
  Itoh Michiko、Suganami Takayoshi、Kato Hideaki、Kanai Sayaka、Shirakawa Ibuki、Sakai Takeru、Goto Toshihiro、Asakawa Masahiro、Hidaka Isao、Sakugawa Hiroshi、Ohnishi Koji、Komohara Yoshihiro、Asano Kenichi、Sakaida Isao、Tanaka Masato、Ogawa Yoshihiro
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 22 Pages: 1-16
- DOI
  10.1172/jci.insight.92902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0110, KAKENHI-PROJECT-16K08732, KAKENHI-PROJECT-16K19823, KAKENHI-PUBLICLY-17H05500, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-16H05171, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-16K15234, KAKENHI-PROJECT-16K19331
[Journal Article] Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1.2016
- Author(s)
  Matsushita, N., Suzuki, M., Ikebe, E., Nagashima, S., Inatome, R., Asano, K., Tanaka, M., Matsushita, M., Kondo, E., Iha, H., and Yanagi, S.
- Journal Title
  
  Sci. Rep
  
  Volume: 6 Issue: 1 Pages: 31266-31266
- DOI
  10.1038/srep31266
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01190, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-16K08246, KAKENHI-PROJECT-16K15224, KAKENHI-PROJECT-16K15245
[Journal Article] Intestinal CD169+macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes2015
- Author(s)
  Kenichi Asano, Naomichi Takahashi, Mikiko Ushiki, Misa Monya, Fumiaki Aihara, Erika Kuboki,Shigetaka Moriyama,Mayumi Iida,Hiroshi Kitamura,　Chun-Hong Qiu,Takashi Watanabe, Masato Tanaka
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 7802-7802
- DOI
  10.1038/ncomms8802
- NAID
  120006311913
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-26460401, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089
[Journal Article] Vascular‐resident CD169‐positive Monocytes and Macrophages Control Neutrophil Accumulation in the Kidney with Ischemia‐reperfusion Injury.2015
- Author(s)
  Karasawa K, Asano K, Moriyama S, Ushiki M, Monya M, Iida M, Kuboki E, Yagita H, Uchida K, Nitta K, Tanaka M.
- Journal Title
  
  J. Am. Soc. Nephrol.
  
  Volume: ２６（４） Issue: 4 Pages: 896-906
- DOI
  10.1681/asn.2014020195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089
[Journal Article] γ-SNAP stimulates disassembly of endosomal SNARE complexes and regulates endocytic trafficking pathways.2015
- Author(s)
  Inoue, H., Matsuzaki, Y., Tanaka, A., Hosoi, K., Ichimura, K., Arasaki, K., Wakana, Y., Asano, K., Tanaka, M., Okuzaki, D., Yamamoto, A., Tani, K. and Tagaya, M.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 128 Pages: 2781-2794
- DOI
  10.1242/jcs.158634
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440064, KAKENHI-PROJECT-15K18507, KAKENHI-PLANNED-26110006, KAKENHI-PUBLICLY-26111520, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-26713016, KAKENHI-PROJECT-26440105, KAKENHI-PROJECT-25291029
[Journal Article] Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis.2015
- Author(s)
  Motomura Y, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 35 Issue: 6 Pages: 1423-33
- DOI
  10.1161/atvbaha.114.304846
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09692, KAKENHI-PLANNED-26110006, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-15H04877, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-25461623
[Journal Article] Colony-StimulatingFactor-1 Signaling Suppresses Renal Crystal Formation.2015
- Author(s)
  Taguchi Kazumi, Okada Atsushi, Kitamura Hiroshi, Yasui Takahiro, Naiki Taku, Hamamoto Shuzo, Ando Ryosuke, Mizuno Kentaro, Kawai Noriyasu, Tozawa Keiichi, Asano Kenichi, Tanaka Masato, Miyoshi Ichiro, Kohri Kenjiro
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 25 Issue: 8 Pages: 1680-1697
- DOI
  10.1681/asn.2013060675
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23249074, KAKENHI-PROJECT-23390095, KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24500495, KAKENHI-PROJECT-24592434, KAKENHI-PROJECT-24659716, KAKENHI-PROJECT-24791663, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089
[Journal Article] CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens.2011
- Author(s)
  Asano, Kenichi
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 85-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790396
[Journal Article] CD169-Positive macrophages dominate antitumor immunity by crosspresentins dead cell-associated antieens2011
- Author(s)
  Asano, K., Nabeyama, A., 他6名, Tanaka, M.(9番目)
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 85-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390095
[Journal Article] CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens2011
- Author(s)
  Asano K, et al
- Journal Title
  
  Immunity
  
  Volume: 34 Issue: 1 Pages: 85-95
- DOI
  10.1016/j.immuni.2010.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590546, KAKENHI-PROJECT-23380186, KAKENHI-PROJECT-23390095
[Journal Article]2011
- Author(s)
  Asano K, Nabeyama A, Miyake Y, et al.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 85-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790396
[Patent] がんの予防および／または治療のための医薬組成物2021
- Inventor(s)
  田中正人、浅野謙一、池田直輝、四元聡志
- Industrial Property Rights Holder
  田中正人、浅野謙一、池田直輝、四元聡志
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K06877
[Patent] 多発性骨髄腫の処置のための医薬組成物2021
- Inventor(s)
  田中正人、浅野謙一
- Industrial Property Rights Holder
  田中正人、浅野謙一
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K06877
[Patent] CCL8による免疫細胞の動員が関与する炎症を抑制するための組成物2021
- Inventor(s)
  田中正人、浅野謙一
- Industrial Property Rights Holder
  田中正人、浅野謙一
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K06877
[Patent] がん転移抑制のための医薬組成物2021
- Inventor(s)
  田中正人、浅野謙一、四元聡志、澁谷拓未、池田直輝
- Industrial Property Rights Holder
  田中正人、浅野謙一、四元聡志、澁谷拓未、池田直輝
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K06877
[Patent] 免疫調節作用を有する単球細胞及びその使用方法2018
- Inventor(s)
  浅野謙一、西躰元、田中正人
- Industrial Property Rights Holder
  浅野謙一、西躰元、田中正人
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H04052
[Patent] 炎症性腸疾患を抑制する抗体および該抗体を含む医薬組成物2015
- Inventor(s)
  浅野謙一、田中正人
- Industrial Property Rights Holder
  学校法人東京薬科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-106658
- Filing Date
  2015-07-20
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] EGR2 plays a pivotal role in the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in non-alcoholic steatohepatitis.2024
- Author(s)
  岩田彩花、田中正人、浅野謙一
- Organizer
  第52回　日本免疫学会
- Data Source
  KAKENHI-PROJECT-21K06877
[Presentation] EGR2は単球から線維化促進マクロファージへの分化を促進し、NASHにおける肝線維症を増悪する2023
- Author(s)
  岩田彩花、田中正人、浅野謙一
- Organizer
  第96回　日本生化学会
- Data Source
  KAKENHI-PROJECT-21K06877
[Presentation] Immunoregulatory Ym1+Ly6Chi monocytes expand in the bone marrow during the late phase of inflammation and accelerate tissue repair.2019
- Author(s)
  Kenichi Asano, Naoki Ikeda, Kenta Kikuchi, Masato Tanaka
- Organizer
  Keystone Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] Phenotypic conversion of intestinal CD169+ macrophages by Maf2019
- Author(s)
  Kenta Kikuchi, Masato Tanaka, Kenichi Asano
- Organizer
  Keystone Symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] Neutrophils convert into atypical Ly6G+SiglecF+　cells with neurosupportive properties in olfactory neuroepithelium2019
- Author(s)
  小川慶、浅野謙一、田中正人
- Organizer
  第48回　日本免疫学会
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] Mafによる組織マクロファージの形質変化2018
- Author(s)
  浅野謙一
- Organizer
  第27回　日本Cell death学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] Phenotypic conversion of the colon macrophage phenotype by Maf2018
- Author(s)
  Kenichi Asano
- Organizer
  第91回　日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] Phenotypic conversion of tissue macrophages by Maf2018
- Author(s)
  Kenichi Asano, Kenta Kikuchi, Masato Tanaka
- Organizer
  Australia-Japan Meeting on Cell Death
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] 転写因子c-MafによるCD169陽性マクロファージの形質制御2017
- Author(s)
  菊池　健太、田中　正人、浅野　謙一
- Organizer
  日本生化学会　関東支部会
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] A transcription factor c-Maf acts as the molecular switch that converts CD169+ macrophage phenotype2017
- Author(s)
  K. Kikuchi, M. Tanaka, and K. Asano
- Organizer
  5th Annual Meeting of the Intenational Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] 大腸炎を誘導する腸管マクロファージのサブセット2017
- Author(s)
  浅野　謙一、菊池　健太、田中　正人
- Organizer
  日本薬学会　関東支部会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04052
[Presentation] CD169陽性マクロファージによる死細胞応答と炎症制御2016
- Author(s)
  田中正人、菊池健太、浅野謙一
- Organizer
  第89回　日本生化学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] 組織マクロファージによる死細胞貪食と疾患制御2016
- Author(s)
  浅野謙一
- Organizer
  第25回東京免疫フォーラム
- Place of Presentation
  東京
- Year and Date
  2016-03-01
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] 組織マクロファージによる炎症制御2016
- Author(s)
  浅野謙一、高橋直道、宇敷美貴子、紋谷光沙、粟飯原史明、久保木恵理佳、飯田真弓、北村浩、邱春紅、渡辺貴志、田中正人
- Organizer
  第81回　日本インターフェロン・サイトカイン学会
- Place of Presentation
  長崎
- Year and Date
  2016-05-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] 組織マクロファージによる消化管の炎症制御2016
- Author(s)
  浅野謙一、高橋直道、宇敷美貴子、紋谷光沙、粟飯原史明、久保木恵理佳、森山誉隆、飯田真弓、北村浩、邱春紅、渡辺貴志、田中正人
- Organizer
  第159回　日本獣医学会
- Place of Presentation
  藤沢
- Year and Date
  2016-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] CD169マクロファージによる生体恒常性維持と疾患制御2015
- Author(s)
  浅野謙一、唐澤一徳、久保木恵理佳、宇敷美貴子、田中正人
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  徳島
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] CD169マクロファージによる粘膜免疫の制御2015
- Author(s)
  浅野謙一、高橋直道、宇敷美貴子、紋谷光沙、粟飯原史明、森山誉隆、飯田真弓、北村浩、邱春紅、渡辺貴志、田中正人
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] CD169 macrophages in the lamina propria sense mucosal injury and bacterial invasion2015
- Author(s)
  浅野　謙一、他11名
- Organizer
  Keystone Symposia
- Place of Presentation
  モントリオール
- Year and Date
  2015-03-09
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] CD169 macrophage-CCL8 axis is a therapeutic target for mucosal inflammation2015
- Author(s)
  浅野謙一
- Organizer
  第44回日本免疫学会総会
- Place of Presentation
  札幌
- Year and Date
  2015-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] CD169 macrophages in the lamina propria sense mucosal injury and bacterial invasion2014
- Author(s)
  高橋直道、浅野謙一、他5名
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26460401
[Presentation] Macrophages dictate the direction of immune response against dead cell-associated antigens.2010
- Author(s)
  Asano, Kenichi
- Organizer
  Annual World Congress of Immunodiseases and Therapy
- Place of Presentation
  Beijing, China
- Year and Date
  2010-05-17
- Data Source
  KAKENHI-PROJECT-21790396
[Presentation] Role of CD169+ macrophages in the crosspresentation of cell-associated antigens.2010
- Author(s)
  Asano, Kenichi
- Organizer
  International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790396

1. Komohara Yoshihiro (40449921)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. TANAKA Masato (00294059)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. 大西紘二 (40613378)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 藤原章雄 (70452886)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 濱田理人 (20567630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NISHITAI Gen (60509941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OIKAWA Akira (50442934)

# of Collaborated Projects: 1 results

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8. 哈斯塔 (00644840)

# of Collaborated Projects: 1 results

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9. 池田直輝 (90825473)

# of Collaborated Projects: 1 results

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10. 山崎晶 (40312946)

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11. 三宅健介 (60229812)

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12. 和泉自泰 (70622166)

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13. 瀬川勝盛 (20542971)

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14. 改正恒康 (60224325)

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15. 安友康二 (30333511)

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16. 木村元子 (00345018)

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17. 堀昌平 (50392113)

# of Collaborated Projects: 1 results

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18. KIKUCHI Kenta

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. TAKAHASHI eiki

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# of Collaborated Products: 1 results
20. OHMURAYA Masaki

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# of Collaborated Products: 2 results
21. OKADA Atsushi

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# of Collaborated Products: 1 results
22. HAMAMOTO Shuzo

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# of Collaborated Products: 1 results
23. TAGUCHI Kazumi

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24. Itoh Michiko

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25. 北村浩

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26. 矢野浩夢

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27. 井上弘樹

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# of Collaborated Products: 2 results
28. 多賀谷光男

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# of Collaborated Products: 1 results
29. 中潟直己

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30. 中川佳子

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31. 柳茂

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32. 佐藤英世

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33. 本村良知

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34. 内田信一

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35. 米田敦子

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36. 戸澤啓一

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37. 郡健二郎

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38. 安井孝周

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39. 菅波孝祥

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40. 有田誠

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# of Collaborated Products: 1 results

ASANO KENICHI 浅野 謙一

ASANO Kenichi 浅野 謙一

Research Projects

Research Products

Co-Researchers

好中球様単球の誘導機構と腸炎の病態形成における役割の解明Principal Investigator

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Differentiation of non-canonical regulatory monocytes triggered by perturbation in inner selfPrincipal Investigator

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Self-referential immune perception

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Development of liver fibrosis by monocyte-derived macrophagesPrincipal Investigator

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The significance of macrophages in anti-cancer immune responses

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Immune regulation by dead intestinal epithelial cellsPrincipal Investigator

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The significance of macrophages in several diseases

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Regulation of Mucosal Immunity by CD169 MacrophagesPrincipal Investigator

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Mechanisms of immunoregulation by dead cell clearance

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CD169陽性マクロファージの分化制御機構の解明Principal Investigator

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The role of CD169 macrophages in anti-tumor immunity induced by dead tumor cells

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Clearance of Dead Tumor Cells and Tumor ImmunityPrincipal Investigator

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[Book] Chronic Inflammation2016

Author(s)

Total Pages

ASANO KENICHI 浅野謙一

ASANO Kenichi 浅野謙一