Ashida Hiroshi 芦田浩

… Alternative Names

ASHIDA Hiroshi 芦田浩

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Researcher Number	10535115
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2017 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2016: 千葉大学, 真菌医学研究センター, 特任准教授 2015: 東京大学, 医科学研究所, 特任准教授 2012 – 2014: 東京大学, 医科学研究所, 特任助教 2010 – 2011: The University of Tokyo, 医科学研究所, 助教 2009: The University of Tokyo, 医科学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) / Bacteriology (including Mycology) / Bacteriology (including Mycology)
Keywords	Principal Investigator エフェクター / 赤痢菌 / 炎症 / 病原細菌 / 腸管病原菌 / 細胞死 / 自然免疫 / 感染 / ユビキチン / 感染マウスモデル … More / 腸内細菌叢 / 下痢原性大腸菌 / 病原細菌感染 / 自然免疫応答 / pyroptosis / necroptosis / apoptosis / caspase-8 / 腸管病原細菌 / I型インターフェロン / シグナル伝達 / NF-〓B / 免疫応答 / NF-κB Less

下痢原性大腸菌による重症化機構の解明と新規治療薬開発の基盤形成Principal Investigator
- Principal Investigator
  
  芦田浩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of bacterial strategies that counteract host defense cross-talkPrincipal Investigator
- Principal Investigator
  
  Ashida Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Tokyo Medical and Dental University
Cross-sectional analysis of infectious strategies of enteric bacterial pathogensPrincipal Investigator
- Principal Investigator
  
  ASHIDA HIROSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokyo Medical and Dental University
  Chiba University
The comprehensive study of bacterial IpaH family effectorsPrincipal Investigator
- Principal Investigator
  
  Ashida Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  The University of Tokyo
病原細菌感染における宿主細胞の免疫応答解明Principal Investigator
- Principal Investigator
  
  芦田浩, KIM Minsoo, 金玟秀
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Molecular analysis of Shigella effector IpaH E3 ligase activityPrincipal Investigator
- Principal Investigator
  
  ASHIDA Hiroshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
Analysis of Shigella type III effector mediated downregulation mechanism of host inflammatory response.Principal Investigator
- Principal Investigator
  
  ASHIDA Hiroshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo

[Book] 炎症と免疫2022
- Author(s)
  岩澤　茉莉絵、芦田　浩、鈴木　敏彦、笹川　千尋
- Total Pages
  5
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-21H02728
[Book] 月刊「細胞」,54(10)2022
- Author(s)
  芦田　浩、鈴木　敏彦
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21H02728
[Book] 感染・炎症・免疫2013
- Author(s)
  芦田浩、笹川千尋
- Publisher
  医薬の門社
- Data Source
  KAKENHI-PROJECT-25460527
[Book] 実験医学増刊感染・共生・生体防御システム2012
- Author(s)
  芦田　浩
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23790472
[Book] 感染・炎症・免疫 vol.40, No.32010
- Author(s)
  芦田浩、笹川千尋
- Data Source
  KAKENHI-PROJECT-21790414
[Book] 実験医学2010
- Author(s)
  芦田浩、笹川千尋
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21790414
[Book] 実験医学 vol.28, No.82010
- Author(s)
  芦田浩、笹川千尋
- Data Source
  KAKENHI-PROJECT-21790414
[Book] 感染・炎症・免疫2010
- Author(s)
  芦田浩、笹川千尋
- Publisher
  医薬の門社
- Data Source
  KAKENHI-PROJECT-21790414
[Book] 実験医学増刊感染症-ウイルス・細菌・寄生虫の感染戦略2009
- Author(s)
  芦田浩、笹川千尋
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21790414
[Book] 実験医学増刊感染症-ウイルス・細菌・寄生虫の感染戦略2009
- Author(s)
  芦田浩、笹川千尋
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease2023
- Author(s)
  Umeda Satoko、　Sujino Tomohisa、、、Shiomi Daisuke、Ashida Hiroshi、Kanai Takanori
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 16 Issue: 6 Pages: 1011-1031
- DOI
  10.1016/j.jcmgh.2023.08.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K17415, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27404, KAKENHI-PROJECT-23K27590
[Journal Article] Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer2023
- Author(s)
  Suzuki Toshihiko、Boonyaleka Kotchakorn、Okano Tokuju、Iida Tamako、Yoshida Mitsunori、Fukano Hanako、Hoshino Yoshihiko、Iwakura Yoichiro、Ablordey Anthony S.、Ashida Hiroshi
- Journal Title
  
  PLOS Pathogens
  
  Volume: 19 Issue: 11 Pages: e1011747-e1011747
- DOI
  10.1371/journal.ppat.1011747
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22K17011, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127
[Journal Article] The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis2023
- Author(s)
  Miyamoto Kentaro、Sujino Tomohisa、...、Kanai Takanori
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 113005-113005
- DOI
  10.1016/j.celrep.2023.113005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27590
[Journal Article] <i>Fusobacterium nucleatum</i> infection activates the noncanonical inflammasome and exacerbates inflammatory response in DSS‐induced colitis2023
- Author(s)
  Boonyaleka Kotchakorn、Okano Tokuju、Iida Tamako、Leewananthawet Anongwee、Sasai Miwa、Yamamoto Masahiro、Ashida Hiroshi、Suzuki Toshihiko
- Journal Title
  
  European Journal of Immunology
  
  Volume: 53 Issue: 11 Pages: 1-13
- DOI
  10.1002/eji.202350455
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22K17011, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127
[Journal Article] A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment2021
- Author(s)
  Kinoshita-Daitoku, R., Kiga, K., Miyakoshi, M. et al.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 2085-2085
- DOI
  10.1038/s41467-021-22317-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03464, KAKENHI-PROJECT-17K14974, KAKENHI-PROJECT-19K16641, KAKENHI-PROJECT-19H03473, KAKENHI-PROJECT-20K16244, KAKENHI-PROJECT-18KK0266, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-21H02730, KAKENHI-PROJECT-23K21171, KAKENHI-PROJECT-21K19666
[Journal Article] Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation2021
- Author(s)
  Kurashima Yosuke、Kigoshi Takaaki、Murasaki Sayuri、Arai Fujimi、Shimada Kaoru、Seki Natsumi、Kim Yun-Gi、Hase Koji、Ohno Hiroshi、Kawano Kazuya、Ashida Hiroshi、Suzuki Toshihiko、Morimoto Masako、Saito Yukari、Sasou Ai、Goda Yuki、Yuki Yoshikazu、Inagaki Yutaka、Iijima Hideki、Suda Wataru、Hattori Masahira
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1067-1067
- DOI
  10.1038/s41467-021-21277-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22627, KAKENHI-PROJECT-20K21530, KAKENHI-PROJECT-20H00509, KAKENHI-PROJECT-17H04159, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-19H03450, KAKENHI-PROJECT-19H03467, KAKENHI-PROJECT-20H03490, KAKENHI-PROJECT-19K22634, KAKENHI-PROJECT-18H05280, KAKENHI-PROJECT-18KK0432, KAKENHI-PROJECT-21H02728
[Journal Article] Effect of low oxygen concentration on activation of inflammation by Helicobacter pylori2021
- Author(s)
  Adiza Abass, Tokuju Okano, Kotchakorn Boonyaleka, RyoKinoshita-Daitoku, Shoji Yamaoka, Hiroshi Ashida, Toshihiko Suzuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 560 Pages: 179-185
- DOI
  10.1016/j.bbrc.2021.04.123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21J00572, KAKENHI-PROJECT-20K16244, KAKENHI-PROJECT-21H02728
[Journal Article] Shigella effector IpaH4.5 targets 19S regulatory subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.2019
- Author(s)
  Otsubo R, Mimura H, Ashida H, Hamazaki J, Murata S, Sasakawa C.
- Journal Title
  
  Cell Microbiol.
  
  Volume: 21 Issue: 3 Pages: e12974-e12974
- DOI
  10.1111/cmi.12974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-16H05186, KAKENHI-PROJECT-26000014
[Journal Article] Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis.2019
- Author(s)
  Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T, Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K, Sato T, Kanai T.
- Journal Title
  
  Nat Microbiol.
  
  Volume: 4 Issue: 3 Pages: 492-503
- DOI
  10.1038/s41564-018-0333-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18K15794, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-16K09374, KAKENHI-PROJECT-16K15293, KAKENHI-PROJECT-19K22544, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-19H03455, KAKENHI-PROJECT-16H05186, KAKENHI-PROJECT-16K08091
[Journal Article] Porphyromonas gingivalis triggers NLRP3-mediated inflammasome activation of macrophages in a bacterial gingipains-independent manner.2018
- Author(s)
  Tokuju Okano, Hiroshi Ashida, Shiho Suzuki, Mikio Shoji, Koji Nakayama, Toshihiko Suzuki,
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 48 Issue: 12 Pages: 1965-1974
- DOI
  10.1002/eji.201847658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08772, KAKENHI-PROJECT-16H05504, KAKENHI-PROJECT-16K11451, KAKENHI-PROJECT-16H05186
[Journal Article] Bacterial E3 ligase effectors exploit host ubiquitin systems2017
- Author(s)
  Ashida H & Sasakawa C
- Journal Title
  
  Curr Opin in Microbiol
  
  Volume: 35 Pages: 16-22
- DOI
  10.1016/j.mib.2016.11.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05186
[Journal Article] 病原細菌によるインフラマソーム制御戦略2017
- Author(s)
  芦田　浩、鈴木　志穂、鈴木　敏彦
- Journal Title
  
  細胞
  
  Volume: 49 Pages: 695-699
- Data Source
  KAKENHI-PROJECT-16H05186
[Journal Article] 赤痢菌による自然免疫抑制戦略の解明2017
- Author(s)
  芦田　浩、鈴木　敏彦、笹川　千尋
- Journal Title
  
  化学療法の領域
  
  Volume: 33 Pages: 1281-1288
- Data Source
  KAKENHI-PROJECT-16H05186
[Journal Article] Shigella IpaH family effectors as a versatile model for studying pathogenic bacteria2016
- Author(s)
  Ashida H & Sasakawa C
- Journal Title
  
  Front Cell. Infect. Microbiol
  
  Volume: 5 Pages: 100-100
- DOI
  10.3389/fcimb.2015.00100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-23000012
[Journal Article] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015
- Author(s)
  Ashida H, Mimuro H, Sasakawa C
- Journal Title
  
  Frontier Immunology
  
  Volume: In press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460527
[Journal Article] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015
- Author(s)
  Ashida H, Mimuro H, & Sasakawa C
- Journal Title
  
  Front Immunol
  
  Volume: 6 Pages: 219-219
- DOI
  10.3389/fimmu.2015.00219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-23000012
[Journal Article] Exploitation of the host ubiquitin system by human bacterial pathogens2014
- Author(s)
  Ashida H, Kim M, & Sasakawa C
- Journal Title
  
  Nature Reviews Microbiology
  
  Volume: 12 Pages: 1-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460527
[Journal Article] Shigella hacks host immune responses by reprogramming the host epigenome2014
- Author(s)
  Ashida H, Sasakawa C
- Journal Title
  
  EMBO J
  
  Volume: 33 Issue: 22 Pages: 2598-600
- DOI
  10.15252/embj.201489934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460527
[Journal Article] Exploitation of the host ubiquitin system by human bacterial pathogens2014
- Author(s)
  Ashida H et. al
- Journal Title
  
  Nat Rev Microbiol
  
  Volume: 12 Issue: 6 Pages: 399-413
- DOI
  10.1038/nrmicro3259
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711
[Journal Article] Manipulation of the host cell death pathway by Shigella2014
- Author(s)
  Ashida H, Kim M, Sasakawa C
- Journal Title
  
  Cell Microbiol
  
  Volume: 16 Issue: 12 Pages: 1757-66
- DOI
  10.1111/cmi.12367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460527
[Journal Article] Shigella IpaH7.8 E3 ligase targets glomulin and activates inflammasomes to demolish macrophages2014
- Author(s)
  Suzuki S et.al
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Issue: 40
- DOI
  10.1073/pnas.1324021111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-26860283
[Journal Article] The Shigella OspC3 effector inhibits Cspase-4, antagonizes inflammatory cell death, and promotes epithelial infection2013
- Author(s)
  Kobayashi T, et. al
- Journal Title
  
  Cell Host Microbe
  
  Volume: 13 Issue: 5 Pages: 570-583
- DOI
  10.1016/j.chom.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PUBLICLY-24117507, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555
[Journal Article] Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells.2013
- Author(s)
  Ashida H, Nakano H, Sasakawa C.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 9 Issue: 6 Pages: e1003409-e1003409
- DOI
  10.1371/journal.ppat.1003409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-24390100, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25670167
[Journal Article] Bacteria and host interactions in the gut epithelial barrier2012
- Author(s)
  Ashida, H., Ogawa, M., Kim, M., Mimuro, H., and Sasakawa C
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 8 Pages: 36-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] A bacterial effector deamidates Ubc13 to dampen the inflammatory response2012
- Author(s)
  Sanada, T., Kim, M., Mimuro, H., Suzuki, M., Ogawa, M., Oyama, A., Ashida, H., Kobyashi, T., Koyama, T., Nagai, S., Shibata, Y., Gohda, J., Inoue, J., Mizushima, T., and Sasakawa, C
- Journal Title
  
  Nature
  
  Volume: 483 Pages: 623-626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Bacteria and host interactions in the gut epithelial barrier.2012
- Author(s)
  Ashida H, Ogawa M, Kim M, Mimuro H, &Sasakawa C.
- Journal Title
  
  Nature Chem Biol.
  
  Volume: 8 Pages: 36-45
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.2012
- Author(s)
  Sanada T, Kim M, Mimuro H, Suzuki M, Ogawa M, Oyama A, Ashida H, Kobyashi T, Koyama T, Nagai S, Shibata Y, Gohda J, Inoue J, Mizushima T, & Sasakawa C.
- Journal Title
  
  Nature.
  
  Volume: 483 Pages: 623-626
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] A tecpr1-dependent selective autophagy pathway targets bacterial pathogens.2011
- Author(s)
  Ogawa M, Yoshikawa Y, Kobayashi T, Mimuro H, Fukumatsu M, Kiga K, Piao Z, Ashida H, Yoshida M, Kakuta S, Koyama T, Goto Y, Nagatake T, Nagai S, Kiyono H, Kawalec M, Reichhart JM, Sasakawa C.
- Journal Title
  
  Cell Host Microbe.
  
  Volume: 9 Pages: 376-89
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011
- Author(s)
  Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, Sasakawa C.
- Journal Title
  
  Curr Opin in Microbiol. 14
  
  Pages: 16-23
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] Cell death and infection: a double-edged sword for host and pathogen survival.2011
- Author(s)
  Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, & Sasakawa C.
- Journal Title
  
  J Cell Biol.
  
  Volume: 195 Pages: 931-42
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Cell death and infection: a double-edged sword for host and pathogen survival2011
- Author(s)
  Ashida, H., Mimuro, H., Ogawa, M., Kobayashi, T., Sanada, T., Kim, M., and Sasakawa, C
- Journal Title
  
  Journal of Cell BIology
  
  Volume: 195 Pages: 931-942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011
- Author(s)
  Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, Sasakawa C
- Journal Title
  
  Current Opinion in Microbioly.
  
  Volume: 14 Pages: 16-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innate immune system2011
- Author(s)
  Ashida, H., Ogawa, M., Mimuro, H., Kobayashi, T., Sanada, T., and Sasakawa, C
- Journal Title
  
  Current Opinion in Immunology
  
  Volume: 23 Pages: 448-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens2011
- Author(s)
  Ogawa, M., Yoshikawa, Y., Kobayashi, T., Mimuro, H., Fukumatsu, M., Kiga, K., Piao, Z., Ashida, H.,....., Kawalec, M., Reichhart, J. M., and Sasakawa, C
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 9 Pages: 376-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011
- Author(s)
  Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, & Sasakawa C.
- Journal Title
  
  Curr Opin in Microbiol.
  
  Volume: 14 Pages: 16-23
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] BabA-mediated adherence is a potentiator of the Helicobacter pylori Type IV secretion system activity.2011
- Author(s)
  Ishijima N, Suzuki M, Ashida H, Ichikawa Y, Kanegae Y, Saito I, Boren T, Haas R, Sasakawa C, Mimuro H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286 Pages: 25256-64
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity.2011
- Author(s)
  Ishijima, N., Suzuki, M., Ashida, H., Ichikawa, Y., Kanegae, Y., Saito, I., Borén, T., Haas, R., Sasakawa, C., and Mimuro, H
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 25256-23264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innate immune system.2011
- Author(s)
  Ashida H, Ogawa M, Mimuro H, Kobayashi T, Sanada T, & Sasakawa C.
- Journal Title
  
  Curr Opin in Immunol.
  
  Volume: 23 Pages: 448-55
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Manipulation of autophagy by bacteria for their own benefit.2011
- Author(s)
  Ogawa M, Mimuro H, Yoshikawa Y, Ashida H, & Sasakawa C.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 55 Pages: 459-471
- NAID
  10031121491
- Data Source
  KAKENHI-PROJECT-23790472
[Journal Article] Bacterial interactions with the host epithelium : bacterial countermeasures that disrupt intrinsic epithelial barrier function.2010
- Author(s)
  Kim M, Ashida H, Ogawa M, Mimuro H, Yoshikawa Y, Sasakawa C
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 8 Pages: 20-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 effector targets NEMO/IKK_γ to dampen the host NF-_κB-mediated inflammatory response.2010
- Author(s)
  Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C.
- Journal Title
  
  Nat.Cell.Biol. 12
  
  Pages: 66-73
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response2010
- Author(s)
  Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C
- Journal Title
  
  Nature Cell Biology 12
  
  Pages: 66-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] Bacterial interactions with the host epithelium: bacterial countermeasures that disrupt intrinsic epithelial barrier function.2010
- Author(s)
  Kim M, Ashida H, Ogawa M, Mimuro H, Yoshikawa Y, Sasakawa C.
- Journal Title
  
  Cell Host & Microbe. 8
  
  Pages: 20-35
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] Shigella infection of intestinal epithelium and circumvention of the host in nate defense system2009
- Author(s)
  Ashida H, Ogawa M, Mimuro H, Sasakawa C
- Journal Title
  
  Current Topics Microbioly Immunoly 337
  
  Pages: 231-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790414
[Journal Article] Shigella infection of intestinal epithelium and circumvention of the host innate defense system.2009
- Author(s)
  Ashida H, Ogawa M, Mimuro H, Sasakawa C.
- Journal Title
  
  Curr Top Microbiol Immunol. 337
  
  Pages: 231-55
- Data Source
  KAKENHI-PROJECT-21790414
[Presentation] 赤痢菌による宿主細胞死制御機構の解明2023
- Author(s)
  芦田　浩、鈴木　敏彦
- Organizer
  第166回日本獣医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02728
[Presentation] 腸管病原菌による宿主細胞死制御機構の解明2023
- Author(s)
  芦田　浩、鈴木　敏彦
- Organizer
  第34回日本生体防御学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02728
[Presentation] 腸管病原菌による宿主細胞死制御機構の解明2022
- Author(s)
  芦田　浩、鈴木　敏彦
- Organizer
  第34回微生物シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21H02728
[Presentation] 赤痢菌による新たな細胞死制御機構の解明2018
- Author(s)
  芦田　浩、鈴木　敏彦
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16H05186
[Presentation] The interaction analysis between microbiota and bacterial pathogens2018
- Author(s)
  Hiroshi Ashida, Chihiro Sasakawa, Toshihiko Suzuki
- Organizer
  The 17th Awaji International Forum of Infection and Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05186
[Presentation] Analysis of novel Shigella effector mechanism that regulate host cell death2018
- Author(s)
  Hiroshi Ashida, Toshihiko Suzuki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05186
[Presentation] 腸管病原細菌感染戦略の横断的解析2018
- Author(s)
  芦田　浩、笹川　千尋、鈴木　敏彦
- Organizer
  第22回腸管出血性大腸菌感染症研究会
- Data Source
  KAKENHI-PROJECT-16H05186
[Presentation] ワクチンおよび抗生物質代替創薬開発の基盤となる腸管病原細菌感染マウスモデルの構築とその機能解析2017
- Author(s)
  芦田浩、鈴木敏彦、笹川千尋
- Organizer
  2017年度生命科学系学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05186
[Presentation] EHECマウス腸管感染モデルの構築とその解析2016
- Author(s)
  芦田　浩、笹川　千尋
- Organizer
  第20回　腸管出血性大腸菌（EHEC）感染症研究会
- Place of Presentation
  富山県民共生センターサンフォルテ
- Year and Date
  2016-11-10
- Data Source
  KAKENHI-PROJECT-16H05186
[Presentation] Shigella manipulates host immune responses by delivering IpaH effector2015
- Author(s)
  Hiroshi Ashida & Chihiro Sasakawa
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES
- Place of Presentation
  Suzhou, China
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] Shigella effector protein hacks host immune responses by targeting type I interferon signaling.2015
- Author(s)
  Hiroshi Ashida & Chihiro Sasakawa
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-25460527
[Presentation] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015
- Author(s)
  Hiroshi Ashida & Chihiro Sasakawa
- Organizer
  The 14th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路島夢舞台国際展示場（兵庫県淡路市）
- Year and Date
  2015-09-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460527
[Presentation] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015
- Author(s)
  Hiroshi Ashida & Chihiro Sasakawa
- Organizer
  The 14th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路島夢舞台国際展示場（兵庫県淡路市）
- Year and Date
  2015-09-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-13F03405
[Presentation] Shigella manipulates host immune responses by delivering IpaH effector2015
- Author(s)
  Hiroshi Ashida & Chihiro Sasakawa
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES
- Place of Presentation
  Suzhou, China
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460527
[Presentation] Shigella effector protein exploits host ubiquitin system2014
- Author(s)
  Hiroshi Ashida & Chihiro Sasakawa
- Organizer
  第３回感染症若手フォーラム
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-25460527
[Presentation] 赤痢菌 IpaH エフェクタータンパクの機能解析"2013
- Author(s)
  芦田浩、笹川千尋
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] 赤痢菌IpaHエフェクタータンパクの機能解析2013
- Author(s)
  芦田　浩
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] Shigella effector protein modulates host inflammatory responses2012
- Author(s)
  Hiroshi Ashida and Chihiro Sasakawa
- Organizer
  第85回日本細菌学会総会(招待講演)
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] Shigella effector protein modulates host inflammatory responses2012
- Author(s)
  芦田浩、笹川千尋
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] Shigella deploy multiple countermeasures against host innate immue responses2011
- Author(s)
  Hiroshi Ashida and Chihiro Sasakawa
- Organizer
  Singapore-Japan Joint Forum Emerging Concepts in Microbiology(招待講演)
- Place of Presentation
  シンガポール
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] Shigella deploy multiple countermeasures against host innate immue responses2011
- Author(s)
  Ashida H and Sasakawa C.
- Organizer
  International Union of Microbiological Societies 2011 Congress.
- Place of Presentation
  Japan
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] Shigella deploy multiple countermeasures against host innate immue responses.''2011
- Author(s)
  Ashida H and Sasakawa C.
- Organizer
  Singapore-Japan Joint Forum Emerging Concepts in Microbiology.
- Place of Presentation
  Singapore
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] Shigella deploy multiple countermeasures against host innate immue responses2011
- Author(s)
  Hiroshi Ashida and Chihiro Sasakawa
- Organizer
  International Union of Microbiological Societies 2011 Congress
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790472
[Presentation] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response2010
- Author(s)
  Hiroshi Ashida, Chihiro Sasakawa
- Organizer
  第10回日韓国際微生物学シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21790414
[Presentation] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKK_γ・ to dampen the host NF-_κ・B-mediated inflammatory response.2010
- Author(s)
  Hiroshi Ashida, Chihiro Sasakawa.
- Organizer
  第10回日韓国際微生物学シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21790414
[Presentation] 赤痢菌エフェクターによる宿主細胞の機能攪乱
- Author(s)
  芦田　浩、笹川　千尋
- Organizer
  第87回細菌学会総会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25460527

1. LEE JIHYE

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KIM Minsoo (50466835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 金玟秀

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HOSHINO Yoshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SUZUKI Shiho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. INAGAKI Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 筋野智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 岡野徳壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 鈴木敏彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 吉田光範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 笹川千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 濱崎純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 宮腰昌利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 寺谷俊昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ashida Hiroshi 芦田 浩

ASHIDA Hiroshi 芦田 浩

Research Projects

Research Products

Co-Researchers

下痢原性大腸菌による重症化機構の解明と新規治療薬開発の基盤形成Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analysis of bacterial strategies that counteract host defense cross-talkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cross-sectional analysis of infectious strategies of enteric bacterial pathogensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The comprehensive study of bacterial IpaH family effectorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

病原細菌感染における宿主細胞の免疫応答解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of Shigella effector IpaH E3 ligase activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Shigella type III effector mediated downregulation mechanism of host inflammatory response.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 炎症と免疫2022

Author(s)

Total Pages

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Data Source

[Book] 月刊「細胞」,54(10)2022

Author(s)

Total Pages

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Data Source

[Book] 感染・炎症・免疫2013

Author(s)

Publisher

Data Source

[Book] 実験医学増刊 感染・共生・生体防御システム2012

Author(s)

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[Book] 感染・炎症・免疫 vol.40, No.32010

Author(s)

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[Book] 実験医学2010

Author(s)

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[Book] 実験医学 vol.28, No.82010

Author(s)

Data Source

[Book] 感染・炎症・免疫2010

Author(s)

Publisher

Data Source

[Book] 実験医学増刊 感染症-ウイルス・細菌・寄生虫の感染戦略2009

Ashida Hiroshi 芦田浩

ASHIDA Hiroshi 芦田浩

[Book] 実験医学増刊感染・共生・生体防御システム2012

[Book] 実験医学増刊感染症-ウイルス・細菌・寄生虫の感染戦略2009

[Book] 実験医学増刊感染症-ウイルス・細菌・寄生虫の感染戦略2009