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Ashida Hiroshi  芦田 浩

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ASHIDA Hiroshi  芦田 浩

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Researcher Number 10535115
Other IDs
Affiliation (Current) 2025: 東京科学大学, 大学院医歯学総合研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授
2017 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授
2016: 千葉大学, 真菌医学研究センター, 特任准教授
2015: 東京大学, 医科学研究所, 特任准教授
2012 – 2014: 東京大学, 医科学研究所, 特任助教
2010 – 2011: The University of Tokyo, 医科学研究所, 助教
2009: The University of Tokyo, 医科学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) / Bacteriology (including Mycology) / Bacteriology (including Mycology)
Keywords
Principal Investigator
エフェクター / 赤痢菌 / 炎症 / 病原細菌 / 腸管病原菌 / 細胞死 / 自然免疫 / 感染 / ユビキチン / 感染マウスモデル … More / 腸内細菌叢 / 下痢原性大腸菌 / 病原細菌感染 / 自然免疫応答 / pyroptosis / necroptosis / apoptosis / caspase-8 / 腸管病原細菌 / I型インターフェロン / シグナル伝達 / NF-〓B / 免疫応答 / NF-κB Less
  • Research Projects

    (7 results)
  • Research Products

    (81 results)
  • Co-Researchers

    (14 People)
  •  下痢原性大腸菌による重症化機構の解明と新規治療薬開発の基盤形成Principal Investigator

    • Principal Investigator
      芦田 浩
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49050:Bacteriology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of bacterial strategies that counteract host defense cross-talkPrincipal Investigator

    • Principal Investigator
      Ashida Hiroshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49050:Bacteriology-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Cross-sectional analysis of infectious strategies of enteric bacterial pathogensPrincipal Investigator

    • Principal Investigator
      ASHIDA HIROSHI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Tokyo Medical and Dental University
      Chiba University
  •  The comprehensive study of bacterial IpaH family effectorsPrincipal Investigator

    • Principal Investigator
      Ashida Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      The University of Tokyo
  •  病原細菌感染における宿主細胞の免疫応答解明Principal Investigator

    • Principal Investigator
      芦田 浩, KIM Minsoo, 金 玟秀
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Molecular analysis of Shigella effector IpaH E3 ligase activityPrincipal Investigator

    • Principal Investigator
      ASHIDA Hiroshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Analysis of Shigella type III effector mediated downregulation mechanism of host inflammatory response.Principal Investigator

    • Principal Investigator
      ASHIDA Hiroshi
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] 炎症と免疫2022

    • Author(s)
      岩澤 茉莉絵、芦田 浩、鈴木 敏彦、笹川 千尋
    • Total Pages
      5
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-21H02728
  • [Book] 月刊「細胞」,54(10)2022

    • Author(s)
      芦田 浩、鈴木 敏彦
    • Total Pages
      4
    • Publisher
      ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-21H02728
  • [Book] 感染・炎症・免疫2013

    • Author(s)
      芦田 浩、笹川 千尋
    • Publisher
      医薬の門社
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Book] 実験医学増刊 感染・共生・生体防御システム2012

    • Author(s)
      芦田 浩
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Book] 感染・炎症・免疫 vol.40, No.32010

    • Author(s)
      芦田浩、笹川千尋
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Book] 実験医学2010

    • Author(s)
      芦田浩、笹川千尋
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Book] 実験医学 vol.28, No.82010

    • Author(s)
      芦田浩、笹川千尋
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Book] 感染・炎症・免疫2010

    • Author(s)
      芦田浩、笹川千尋
    • Publisher
      医薬の門社
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Book] 実験医学増刊 感染症-ウイルス・細菌・寄生虫の感染戦略2009

    • Author(s)
      芦田浩、笹川千尋
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Book] 実験医学増刊 感染症-ウイルス・細菌・寄生虫の感染戦略2009

    • Author(s)
      芦田浩、笹川千尋
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease2023

    • Author(s)
      Umeda Satoko、 Sujino Tomohisa、、、Shiomi Daisuke、Ashida Hiroshi、Kanai Takanori
    • Journal Title

      Cellular and Molecular Gastroenterology and Hepatology

      Volume: 16 Issue: 6 Pages: 1011-1031

    • DOI

      10.1016/j.jcmgh.2023.08.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K17415, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27404, KAKENHI-PROJECT-23K27590
  • [Journal Article] Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer2023

    • Author(s)
      Suzuki Toshihiko、Boonyaleka Kotchakorn、Okano Tokuju、Iida Tamako、Yoshida Mitsunori、Fukano Hanako、Hoshino Yoshihiko、Iwakura Yoichiro、Ablordey Anthony S.、Ashida Hiroshi
    • Journal Title

      PLOS Pathogens

      Volume: 19 Issue: 11 Pages: e1011747-e1011747

    • DOI

      10.1371/journal.ppat.1011747

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22K17011, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127
  • [Journal Article] The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis2023

    • Author(s)
      Miyamoto Kentaro、Sujino Tomohisa、...、Kanai Takanori
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 8 Pages: 113005-113005

    • DOI

      10.1016/j.celrep.2023.113005

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27590
  • [Journal Article] <i>Fusobacterium nucleatum</i> infection activates the noncanonical inflammasome and exacerbates inflammatory response in DSS‐induced colitis2023

    • Author(s)
      Boonyaleka Kotchakorn、Okano Tokuju、Iida Tamako、Leewananthawet Anongwee、Sasai Miwa、Yamamoto Masahiro、Ashida Hiroshi、Suzuki Toshihiko
    • Journal Title

      European Journal of Immunology

      Volume: 53 Issue: 11 Pages: 1-13

    • DOI

      10.1002/eji.202350455

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22K17011, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127
  • [Journal Article] A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment2021

    • Author(s)
      Kinoshita-Daitoku, R., Kiga, K., Miyakoshi, M. et al.
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 2085-2085

    • DOI

      10.1038/s41467-021-22317-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03464, KAKENHI-PROJECT-17K14974, KAKENHI-PROJECT-19K16641, KAKENHI-PROJECT-19H03473, KAKENHI-PROJECT-20K16244, KAKENHI-PROJECT-18KK0266, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-21H02730, KAKENHI-PROJECT-23K21171, KAKENHI-PROJECT-21K19666
  • [Journal Article] Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation2021

    • Author(s)
      Kurashima Yosuke、Kigoshi Takaaki、Murasaki Sayuri、Arai Fujimi、Shimada Kaoru、Seki Natsumi、Kim Yun-Gi、Hase Koji、Ohno Hiroshi、Kawano Kazuya、Ashida Hiroshi、Suzuki Toshihiko、Morimoto Masako、Saito Yukari、Sasou Ai、Goda Yuki、Yuki Yoshikazu、Inagaki Yutaka、Iijima Hideki、Suda Wataru、Hattori Masahira
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1067-1067

    • DOI

      10.1038/s41467-021-21277-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22627, KAKENHI-PROJECT-20K21530, KAKENHI-PROJECT-20H00509, KAKENHI-PROJECT-17H04159, KAKENHI-PROJECT-17H04166, KAKENHI-PROJECT-19H03450, KAKENHI-PROJECT-19H03467, KAKENHI-PROJECT-20H03490, KAKENHI-PROJECT-19K22634, KAKENHI-PROJECT-18H05280, KAKENHI-PROJECT-18KK0432, KAKENHI-PROJECT-21H02728
  • [Journal Article] Effect of low oxygen concentration on activation of inflammation by Helicobacter pylori2021

    • Author(s)
      Adiza Abass, Tokuju Okano, Kotchakorn Boonyaleka, RyoKinoshita-Daitoku, Shoji Yamaoka, Hiroshi Ashida, Toshihiko Suzuki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 560 Pages: 179-185

    • DOI

      10.1016/j.bbrc.2021.04.123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21J00572, KAKENHI-PROJECT-20K16244, KAKENHI-PROJECT-21H02728
  • [Journal Article] Shigella effector IpaH4.5 targets 19S regulatory subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.2019

    • Author(s)
      Otsubo R, Mimura H, Ashida H, Hamazaki J, Murata S, Sasakawa C.
    • Journal Title

      Cell Microbiol.

      Volume: 21 Issue: 3 Pages: e12974-e12974

    • DOI

      10.1111/cmi.12974

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-16H05186, KAKENHI-PROJECT-26000014
  • [Journal Article] Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis.2019

    • Author(s)
      Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T, Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K, Sato T, Kanai T.
    • Journal Title

      Nat Microbiol.

      Volume: 4 Issue: 3 Pages: 492-503

    • DOI

      10.1038/s41564-018-0333-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18K15794, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-16K09374, KAKENHI-PROJECT-16K15293, KAKENHI-PROJECT-19K22544, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-19H03455, KAKENHI-PROJECT-16H05186, KAKENHI-PROJECT-16K08091
  • [Journal Article] Porphyromonas gingivalis triggers NLRP3-mediated inflammasome activation of macrophages in a bacterial gingipains-independent manner.2018

    • Author(s)
      Tokuju Okano, Hiroshi Ashida, Shiho Suzuki, Mikio Shoji, Koji Nakayama, Toshihiko Suzuki,
    • Journal Title

      Eur. J. Immunol.

      Volume: 48 Issue: 12 Pages: 1965-1974

    • DOI

      10.1002/eji.201847658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08772, KAKENHI-PROJECT-16H05504, KAKENHI-PROJECT-16K11451, KAKENHI-PROJECT-16H05186
  • [Journal Article] Bacterial E3 ligase effectors exploit host ubiquitin systems2017

    • Author(s)
      Ashida H & Sasakawa C
    • Journal Title

      Curr Opin in Microbiol

      Volume: 35 Pages: 16-22

    • DOI

      10.1016/j.mib.2016.11.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Journal Article] 病原細菌によるインフラマソーム制御戦略2017

    • Author(s)
      芦田 浩、鈴木 志穂、鈴木 敏彦
    • Journal Title

      細胞

      Volume: 49 Pages: 695-699

    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Journal Article] 赤痢菌による自然免疫抑制戦略の解明2017

    • Author(s)
      芦田 浩、鈴木 敏彦、笹川 千尋
    • Journal Title

      化学療法の領域

      Volume: 33 Pages: 1281-1288

    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Journal Article] Shigella IpaH family effectors as a versatile model for studying pathogenic bacteria2016

    • Author(s)
      Ashida H & Sasakawa C
    • Journal Title

      Front Cell. Infect. Microbiol

      Volume: 5 Pages: 100-100

    • DOI

      10.3389/fcimb.2015.00100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-23000012
  • [Journal Article] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015

    • Author(s)
      Ashida H, Mimuro H, Sasakawa C
    • Journal Title

      Frontier Immunology

      Volume: In press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Journal Article] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015

    • Author(s)
      Ashida H, Mimuro H, & Sasakawa C
    • Journal Title

      Front Immunol

      Volume: 6 Pages: 219-219

    • DOI

      10.3389/fimmu.2015.00219

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-23000012
  • [Journal Article] Exploitation of the host ubiquitin system by human bacterial pathogens2014

    • Author(s)
      Ashida H, Kim M, & Sasakawa C
    • Journal Title

      Nature Reviews Microbiology

      Volume: 12 Pages: 1-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Journal Article] Shigella hacks host immune responses by reprogramming the host epigenome2014

    • Author(s)
      Ashida H, Sasakawa C
    • Journal Title

      EMBO J

      Volume: 33 Issue: 22 Pages: 2598-600

    • DOI

      10.15252/embj.201489934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460527
  • [Journal Article] Exploitation of the host ubiquitin system by human bacterial pathogens2014

    • Author(s)
      Ashida H et. al
    • Journal Title

      Nat Rev Microbiol

      Volume: 12 Issue: 6 Pages: 399-413

    • DOI

      10.1038/nrmicro3259

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711
  • [Journal Article] Manipulation of the host cell death pathway by Shigella2014

    • Author(s)
      Ashida H, Kim M, Sasakawa C
    • Journal Title

      Cell Microbiol

      Volume: 16 Issue: 12 Pages: 1757-66

    • DOI

      10.1111/cmi.12367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-25460527
  • [Journal Article] Shigella IpaH7.8 E3 ligase targets glomulin and activates inflammasomes to demolish macrophages2014

    • Author(s)
      Suzuki S et.al
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 111 Issue: 40

    • DOI

      10.1073/pnas.1324021111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-26860283
  • [Journal Article] The Shigella OspC3 effector inhibits Cspase-4, antagonizes inflammatory cell death, and promotes epithelial infection2013

    • Author(s)
      Kobayashi T, et. al
    • Journal Title

      Cell Host Microbe

      Volume: 13 Issue: 5 Pages: 570-583

    • DOI

      10.1016/j.chom.2013.04.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PUBLICLY-24117507, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555
  • [Journal Article] Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells.2013

    • Author(s)
      Ashida H, Nakano H, Sasakawa C.
    • Journal Title

      PLoS Pathog.

      Volume: 9 Issue: 6 Pages: e1003409-e1003409

    • DOI

      10.1371/journal.ppat.1003409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-24390100, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25670167
  • [Journal Article] Bacteria and host interactions in the gut epithelial barrier2012

    • Author(s)
      Ashida, H., Ogawa, M., Kim, M., Mimuro, H., and Sasakawa C
    • Journal Title

      Nature Chemical Biology

      Volume: 8 Pages: 36-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] A bacterial effector deamidates Ubc13 to dampen the inflammatory response2012

    • Author(s)
      Sanada, T., Kim, M., Mimuro, H., Suzuki, M., Ogawa, M., Oyama, A., Ashida, H., Kobyashi, T., Koyama, T., Nagai, S., Shibata, Y., Gohda, J., Inoue, J., Mizushima, T., and Sasakawa, C
    • Journal Title

      Nature

      Volume: 483 Pages: 623-626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Bacteria and host interactions in the gut epithelial barrier.2012

    • Author(s)
      Ashida H, Ogawa M, Kim M, Mimuro H, &Sasakawa C.
    • Journal Title

      Nature Chem Biol.

      Volume: 8 Pages: 36-45

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.2012

    • Author(s)
      Sanada T, Kim M, Mimuro H, Suzuki M, Ogawa M, Oyama A, Ashida H, Kobyashi T, Koyama T, Nagai S, Shibata Y, Gohda J, Inoue J, Mizushima T, & Sasakawa C.
    • Journal Title

      Nature.

      Volume: 483 Pages: 623-626

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] A tecpr1-dependent selective autophagy pathway targets bacterial pathogens.2011

    • Author(s)
      Ogawa M, Yoshikawa Y, Kobayashi T, Mimuro H, Fukumatsu M, Kiga K, Piao Z, Ashida H, Yoshida M, Kakuta S, Koyama T, Goto Y, Nagatake T, Nagai S, Kiyono H, Kawalec M, Reichhart JM, Sasakawa C.
    • Journal Title

      Cell Host Microbe.

      Volume: 9 Pages: 376-89

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011

    • Author(s)
      Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, Sasakawa C.
    • Journal Title

      Curr Opin in Microbiol. 14

      Pages: 16-23

    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] Cell death and infection: a double-edged sword for host and pathogen survival.2011

    • Author(s)
      Ashida H, Mimuro H, Ogawa M, Kobayashi T, Sanada T, Kim M, & Sasakawa C.
    • Journal Title

      J Cell Biol.

      Volume: 195 Pages: 931-42

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Cell death and infection: a double-edged sword for host and pathogen survival2011

    • Author(s)
      Ashida, H., Mimuro, H., Ogawa, M., Kobayashi, T., Sanada, T., Kim, M., and Sasakawa, C
    • Journal Title

      Journal of Cell BIology

      Volume: 195 Pages: 931-942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011

    • Author(s)
      Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, Sasakawa C
    • Journal Title

      Current Opinion in Microbioly.

      Volume: 14 Pages: 16-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innate immune system2011

    • Author(s)
      Ashida, H., Ogawa, M., Mimuro, H., Kobayashi, T., Sanada, T., and Sasakawa, C
    • Journal Title

      Current Opinion in Immunology

      Volume: 23 Pages: 448-455

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens2011

    • Author(s)
      Ogawa, M., Yoshikawa, Y., Kobayashi, T., Mimuro, H., Fukumatsu, M., Kiga, K., Piao, Z., Ashida, H.,....., Kawalec, M., Reichhart, J. M., and Sasakawa, C
    • Journal Title

      Cell Host & Microbe

      Volume: 9 Pages: 376-389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Shigella deploy multiple countermeasures against host innate immune responses.2011

    • Author(s)
      Ashida H, Ogawa M, Kim M, Suzuki S, Sanada T, Punginelli C, Mimuro H, & Sasakawa C.
    • Journal Title

      Curr Opin in Microbiol.

      Volume: 14 Pages: 16-23

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] BabA-mediated adherence is a potentiator of the Helicobacter pylori Type IV secretion system activity.2011

    • Author(s)
      Ishijima N, Suzuki M, Ashida H, Ichikawa Y, Kanegae Y, Saito I, Boren T, Haas R, Sasakawa C, Mimuro H.
    • Journal Title

      J Biol Chem.

      Volume: 286 Pages: 25256-64

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] BabA-mediated adherence is a potentiator of the Helicobacter pylori type IV secretion system activity.2011

    • Author(s)
      Ishijima, N., Suzuki, M., Ashida, H., Ichikawa, Y., Kanegae, Y., Saito, I., Borén, T., Haas, R., Sasakawa, C., and Mimuro, H
    • Journal Title

      Journal of Biological Chemistry

      Volume: 286 Pages: 25256-23264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Shigella are versatile mucosal pathogens that circumvent the host innate immune system.2011

    • Author(s)
      Ashida H, Ogawa M, Mimuro H, Kobayashi T, Sanada T, & Sasakawa C.
    • Journal Title

      Curr Opin in Immunol.

      Volume: 23 Pages: 448-55

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Manipulation of autophagy by bacteria for their own benefit.2011

    • Author(s)
      Ogawa M, Mimuro H, Yoshikawa Y, Ashida H, & Sasakawa C.
    • Journal Title

      Microbiol Immunol.

      Volume: 55 Pages: 459-471

    • NAID

      10031121491

    • Data Source
      KAKENHI-PROJECT-23790472
  • [Journal Article] Bacterial interactions with the host epithelium : bacterial countermeasures that disrupt intrinsic epithelial barrier function.2010

    • Author(s)
      Kim M, Ashida H, Ogawa M, Mimuro H, Yoshikawa Y, Sasakawa C
    • Journal Title

      Cell Host & Microbe

      Volume: 8 Pages: 20-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 effector targets NEMO/IKK_γ to dampen the host NF-_κB-mediated inflammatory response.2010

    • Author(s)
      Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C.
    • Journal Title

      Nat.Cell.Biol. 12

      Pages: 66-73

    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response2010

    • Author(s)
      Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C
    • Journal Title

      Nature Cell Biology 12

      Pages: 66-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] Bacterial interactions with the host epithelium: bacterial countermeasures that disrupt intrinsic epithelial barrier function.2010

    • Author(s)
      Kim M, Ashida H, Ogawa M, Mimuro H, Yoshikawa Y, Sasakawa C.
    • Journal Title

      Cell Host & Microbe. 8

      Pages: 20-35

    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] Shigella infection of intestinal epithelium and circumvention of the host in nate defense system2009

    • Author(s)
      Ashida H, Ogawa M, Mimuro H, Sasakawa C
    • Journal Title

      Current Topics Microbioly Immunoly 337

      Pages: 231-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Journal Article] Shigella infection of intestinal epithelium and circumvention of the host innate defense system.2009

    • Author(s)
      Ashida H, Ogawa M, Mimuro H, Sasakawa C.
    • Journal Title

      Curr Top Microbiol Immunol. 337

      Pages: 231-55

    • Data Source
      KAKENHI-PROJECT-21790414
  • [Presentation] 赤痢菌による宿主細胞死制御機構の解明2023

    • Author(s)
      芦田 浩、鈴木 敏彦
    • Organizer
      第166回日本獣医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02728
  • [Presentation] 腸管病原菌による宿主細胞死制御機構の解明2023

    • Author(s)
      芦田 浩、鈴木 敏彦
    • Organizer
      第34回日本生体防御学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02728
  • [Presentation] 腸管病原菌による宿主細胞死制御機構の解明2022

    • Author(s)
      芦田 浩、鈴木 敏彦
    • Organizer
      第34回微生物シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02728
  • [Presentation] 赤痢菌による新たな細胞死制御機構の解明2018

    • Author(s)
      芦田 浩、鈴木 敏彦
    • Organizer
      第91回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Presentation] The interaction analysis between microbiota and bacterial pathogens2018

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa, Toshihiko Suzuki
    • Organizer
      The 17th Awaji International Forum of Infection and Immunity
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Presentation] Analysis of novel Shigella effector mechanism that regulate host cell death2018

    • Author(s)
      Hiroshi Ashida, Toshihiko Suzuki
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Presentation] 腸管病原細菌感染戦略の横断的解析2018

    • Author(s)
      芦田 浩、笹川 千尋、鈴木 敏彦
    • Organizer
      第22回腸管出血性大腸菌感染症研究会
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Presentation] ワクチンおよび抗生物質代替創薬開発の基盤となる腸管病原細菌感染マウスモデルの構築とその機能解析2017

    • Author(s)
      芦田 浩、鈴木 敏彦、笹川 千尋
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Presentation] EHECマウス腸管感染モデルの構築とその解析2016

    • Author(s)
      芦田 浩、笹川 千尋
    • Organizer
      第20回 腸管出血性大腸菌(EHEC)感染症研究会
    • Place of Presentation
      富山県民共生センターサンフォルテ
    • Year and Date
      2016-11-10
    • Data Source
      KAKENHI-PROJECT-16H05186
  • [Presentation] Shigella manipulates host immune responses by delivering IpaH effector2015

    • Author(s)
      Hiroshi Ashida & Chihiro Sasakawa
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2015-11-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-13F03405
  • [Presentation] Shigella effector protein hacks host immune responses by targeting type I interferon signaling.2015

    • Author(s)
      Hiroshi Ashida & Chihiro Sasakawa
    • Organizer
      第88回 日本細菌学会総会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-03-28
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Presentation] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015

    • Author(s)
      Hiroshi Ashida & Chihiro Sasakawa
    • Organizer
      The 14th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島夢舞台国際展示場(兵庫県淡路市)
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Presentation] Shigella manipulates host immune responses by delivering effector proteins with specific roles2015

    • Author(s)
      Hiroshi Ashida & Chihiro Sasakawa
    • Organizer
      The 14th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島夢舞台国際展示場(兵庫県淡路市)
    • Year and Date
      2015-09-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-13F03405
  • [Presentation] Shigella manipulates host immune responses by delivering IpaH effector2015

    • Author(s)
      Hiroshi Ashida & Chihiro Sasakawa
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2015-11-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Presentation] Shigella effector protein exploits host ubiquitin system2014

    • Author(s)
      Hiroshi Ashida & Chihiro Sasakawa
    • Organizer
      第3回感染症若手フォーラム
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-25460527
  • [Presentation] 赤痢菌 IpaH エフェクタータンパクの機能解析"2013

    • Author(s)
      芦田浩、笹川千尋
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] 赤痢菌IpaHエフェクタータンパクの機能解析2013

    • Author(s)
      芦田 浩
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] Shigella effector protein modulates host inflammatory responses2012

    • Author(s)
      Hiroshi Ashida and Chihiro Sasakawa
    • Organizer
      第85回日本細菌学会総会(招待講演)
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] Shigella effector protein modulates host inflammatory responses2012

    • Author(s)
      芦田浩、笹川千尋
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] Shigella deploy multiple countermeasures against host innate immue responses2011

    • Author(s)
      Hiroshi Ashida and Chihiro Sasakawa
    • Organizer
      Singapore-Japan Joint Forum Emerging Concepts in Microbiology(招待講演)
    • Place of Presentation
      シンガポール
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] Shigella deploy multiple countermeasures against host innate immue responses2011

    • Author(s)
      Ashida H and Sasakawa C.
    • Organizer
      International Union of Microbiological Societies 2011 Congress.
    • Place of Presentation
      Japan
    • Year and Date
      2011-09-08
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] Shigella deploy multiple countermeasures against host innate immue responses.''2011

    • Author(s)
      Ashida H and Sasakawa C.
    • Organizer
      Singapore-Japan Joint Forum Emerging Concepts in Microbiology.
    • Place of Presentation
      Singapore
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] Shigella deploy multiple countermeasures against host innate immue responses2011

    • Author(s)
      Hiroshi Ashida and Chihiro Sasakawa
    • Organizer
      International Union of Microbiological Societies 2011 Congress
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23790472
  • [Presentation] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response2010

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa
    • Organizer
      第10回 日韓国際微生物学シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Presentation] A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKK_γ・ to dampen the host NF-_κ・B-mediated inflammatory response.2010

    • Author(s)
      Hiroshi Ashida, Chihiro Sasakawa.
    • Organizer
      第10回日韓国際微生物学シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21790414
  • [Presentation] 赤痢菌エフェクターによる宿主細胞の機能攪乱

    • Author(s)
      芦田 浩、笹川 千尋
    • Organizer
      第87回 細菌学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460527
  • 1.  LEE JIHYE
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  KIM Minsoo (50466835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  金 玟秀
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  HOSHINO Yoshihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  SUZUKI Shiho
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  INAGAKI Yutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  筋野 智久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  岡野 徳壽
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  鈴木 敏彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  吉田 光範
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  笹川 千尋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 12.  濱崎 純
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  宮腰 昌利
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  寺谷 俊昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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