Otuki Kouji 大朏孝治

… Alternative Names

OTSUKI Koji 大朏孝治

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Researcher Number	10535256
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 島根大学, 学術研究院医学・看護学系, 准教授 2014: 山口大学, 大学院医学系研究科, 助教 2011 – 2014: 山口大学, 医学(系)研究科(研究院), 助教 2009 – 2012: Yamaguchi University, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Psychiatric science Except Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator GDNF / エピジェネティクス / HDAC4 / ヒストン修飾 / 抗うつ薬 / HDAC / antidepressant Except Principal Investigator 気分障害 / 炎症性因子 / アストロサイト … More / ミクログリア / グリア / 神経炎症 / 電気けいれん療法 / 脳画像 / 遺伝子 / 白質走行 / 脳体積 / 双極性障害 / 神経画像 / 躁うつ病 / 前頭葉機能 / レプチン / MRI / グレリン / うつ病 Less

Comprehensive elucidation of anti-neuroinflammatory effects of electroconvulsive treatment
- Principal Investigator
  
  橋岡禎征
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Asahikawa Medical College
Disrupted cortico-limbic network and molecular mechanism in bipolar disorder
- Principal Investigator
  
  MATSUO Koji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
A study of new drug development of target of histone deacetylasePrincipal Investigator
- Principal Investigator
  
  OTUKI Kouji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Neural correlates of plasma acylated ghrelin level in individuals with mood disorders
- Principal Investigator
  
  MATSUO Koji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Analysis of the epigenetic regulation in the mechanism of antidepressants.Principal Investigator
- Principal Investigator
  
  OTUKI Koji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University

All 2022 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 精神疾患診断のための脳形態・機能検査法2012
- Author(s)
  大朏孝治、内田周作、渡辺義文
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-23791336
[Book] 末梢白血球に発現している遺伝子と気分障害, 精神疾患診断のための脳形態・機能検査法2011
- Author(s)
  大朏孝治、内田周作、渡辺義文
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] Improvement in both severe obsessive-compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report2022
- Author(s)
  Mihara Yasuha、Otsuki Koji、Hayashi Mai、Yamashita Satoko、Nagahama Michiharu、Hayashida Maiko、Wake Rei、Hashioka Sadayuki、Abe Satoshi、Inagaki Masatoshi
- Journal Title
  
  Psychiatry and Clinical Neurosciences Reports
  
  Volume: 1 Issue: 2 Pages: 1235-1240
- DOI
  10.1002/pcn5.15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04355, KAKENHI-PROJECT-23K24260
[Journal Article] Effect of Ninjin’yoeito on Lipopolysaccharide-Induced Depressive-Like Behavior and Glial Activation in the Hippocampus2022
- Author(s)
  Muhammad Alim Jaya, Maiko Hayashida, Keiko Tsuchie, Sultana Jannatul Ferdoush Jerin, Rahman Mamunur, Shoko Miura, Michiharu Nagahama, Koji Otsuki, Sadayuki Hashioka, Rei Wake, Tsuyoshi Miyaoka, Andi Jayalangkara Tanra, Jun Horiguchi, Masatoshi Inagaki
- Journal Title
  
  Shimane Journal of Medical Science
  
  Volume: 39 Issue: 1 Pages: 1-13
- DOI
  10.51010/sjms.39.1_1
- ISSN
  0386-5959, 2433-2410
- Year and Date
  2022-05-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24260
[Journal Article] The alteration of hypoxia inducible facter-1 (HIF-1) and its target genenes in mood disorder patients2013
- Author(s)
  Shibata T, Yamagata H, Uchida S, Otsuki K, Hobara T, Higuchi F, Abe N, & Watanabe Y
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry
  
  Volume: 43 Pages: 222-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] うつ病におけるエピジェネティクス2012
- Author(s)
  大朏孝治、内田周作、芳原輝之、山形弘隆、渡邉義文
- Journal Title
  
  日本神経薬理学雑誌
  
  Volume: 32 Pages: 181-186
- NAID
  10031055656
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] Altered sirtuin deacetylase gene expression in patients with a mood disorder2012
- Author(s)
  Abe N, Uchida S, Otsuki K, Hobara T, Yamagata H, Higuchi F, Shibata T, & Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45 Pages: 1106-1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] 気分障害のバイオマーカー開発、とくに白血球での遺伝子発現からみた気分障害の状態診断、亜型分類2012
- Author(s)
  渡邉義文、内田周作、大朏孝治、山形弘隆、芳原輝之、阿部尚子、樋口文宏、綿貫俊夫、松原敏郎
- Journal Title
  
  精神神経学雑誌
  
  Volume: 114 Pages: 812-820
- NAID
  10030970858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] State-dependent changes in the expression of DNA methyltransferases in mood disorder patients2012
- Author(s)
  Higuchi F, Uchida S, Otsuki K, Hobara T, Abe N, Yamagata H, Shibata T, & Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45 Pages: 1295-1300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] ヒストン脱アセチル化酵素阻害剤の早期抗うつ効果発現における分子機構の解析2012
- Author(s)
  芳原輝之、内田周作、山形弘隆、大朏孝治、渡邉義文
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 23 Pages: 35-40
- NAID
  130005395372
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] うつ病とエピジェネティクス2012
- Author(s)
  山形弘隆、内田周作、芳原輝之、大朏孝治、渡邉義文
- Journal Title
  
  精神科
  
  Volume: 20 Pages: 632-38
- NAID
  10029785558
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] State-dependent changes in the expression of DNA methyltransferases in mood disorder patients2011
- Author(s)
  Higuchi F, Uchida S, Yamagata H, Otsuki K, Hobara T, Abe N, Shibata T, Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45(10) Pages: 1295-1300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 12011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Fujimoto M, Otsuki K, Yamagata H, Hobara T, Abe N, Higuchi F, Shibata T, Hasegawa S, Kida S, Nakai A, Watanabe Y
- Journal Title
  
  Proceedings of the National Academy of Science of the United States of America
  
  Volume: 108(4) Pages: 1681-1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] State-dependent changes in the expression of DNA methyltransferases in mood disorder patients.2011
- Author(s)
  Higuchi F, Uchida S, Otsuki K, Hobara T, Abe N, Yamagata H, Shibata T, Watanabe Y.
- Journal Title
  
  J Psychiatr Res in press
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Altered sirtuin deacetylase gene expression in patients with a mood disorder2011
- Author(s)
  Abe N, Uchida S, Otsuki K, Hobara T, Yamagata H, Higuchi F, Shibata T, Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45(8) Pages: 1106-1112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Epigenetic status of Gdnfin the ventral striatum determines susceptibility and adaptation to daily stressful events2011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Otsuki K, Yamagata H, Hobara T, Suzuki T, Miyata N, Watanabe Y
- Journal Title
  
  Neuron
  
  Volume: 69(2) Pages: 359-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events.2011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Otsuki K, Yamagata H, Hobara T, Suzuki T, Miyata N, Watanabe Y.
- Journal Title
  
  Neuron 69
  
  Pages: 79-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1.2011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Fujimoto M, Otsuki K, Yamagata H, Hobara T, Abe N, Higuchi F, Shibata T, Hasegawa S, Kida S, Nakai A, Watanabe Y.
- Journal Title
  
  Proc Natl Acad Sci U S A. 108
  
  Pages: 1681-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] うつ病とエピジェネティクス2011
- Author(s)
  大朏孝治、内田周作、芳原輝之、渡辺義文
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 22 Pages: 89-95
- NAID
  10029785558
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events2011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Otsuki K, Yamagata H, Hobara T, Suzuki T, Miyata N, & Watanabe Y
- Journal Title
  
  Neuron
  
  Volume: 69 Pages: 359-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] Altered sirtuin deacetylase gene expression in patients with a mood disorder.2011
- Author(s)
  Abe N, Uchida S, Otsuki K, Hobara T, Yamagata H, Higuchi F, Shibata T, Watanabe Y.
- Journal Title
  
  J Psychiatr Res in press
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] State-dependent changes in the expression of DNA methyltransferases in mood disorder patients2011
- Author(s)
  Higuchi F, Uohida S, Yamagata H, Otsuki K, Hobara T, Abe N, Shibata T, Watanabe Y
- Journal Title
  
  J Psychiatr Res
  
  Volume: 45 Pages: 1295-1300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 12011
- Author(s)
  Uchida S, Hara K, Kobayashi A, Fujimoto M, Otsuki K, Yamagata H, Hobara T, Abe N, Higuchi F, Shibata T, Hasegawa S, Kida S, Nakai A, & Watanabe Y
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 108 Pages: 1681-1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791336
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder.2010
- Author(s)
  Otsuki K, Uchida S, Wakabayashi Y, Matsubara T, Hobara T, Funato H, Watanabe Y.
- Journal Title
  
  J Psychiatr Res 44
  
  Pages: 378-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Altered gene expression of histone deacetylases in mood disorder patients2010
- Author(s)
  Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, Matsuo K, Suetsugi M, Watanabe Y
- Journal Title
  
  Journal of Psychiatric Research
  
  Volume: 44(5) Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder2010
- Author(s)
  Koji Otsuki, et al.
- Journal Title
  
  Journal of Psychiatric Research
  
  Volume: 44 Pages: 378-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Altered gene expression of histone deacetylases in mood disorder patients.2010
- Author(s)
  Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, Matsuo K, Suetsugi M, Watanabe Y.
- Journal Title
  
  J Psychiatr Res 44
  
  Pages: 70-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder2010
- Author(s)
  Otsuki K, Uchida S, Wakabayashi Y, Matsubara T, Hobara T, Funato H, Watanabe Y
- Journal Title
  
  Journal of Psychiatric Research
  
  Volume: 44(6) Pages: 378-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder.2010
- Author(s)
  Otsuki K
- Journal Title
  
  J Psychiatr Res 44
  
  Pages: 378-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Maternal and genetic factors in stress-resilient and -vulnerable rats: a cross-fostering study.2010
- Author(s)
  Uchida S, Hara K, Kobayashi A, Otsuki K, Hobara T, Yamagata H, Watanabe Y.
- Journal Title
  
  Brain Res 1316
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Aberrant REST-mediated transcriptional regulation in major depressive disorder.2010
- Author(s)
  Otsuki K
- Journal Title
  
  J Psychiatr Res
  
  Volume: 44 Pages: 378-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Journal Article] Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents2010
- Author(s)
  Uchida S, Hara K, Kobayashi A, Funato H, Hobara T, Otsuki K, Yamagata H, McEwen BS, Watanabe Y
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 30(45) Pages: 15007-15018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591519
[Journal Article] Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents.2009
- Author(s)
  Uchida S, Hara K, Kobayashi A, Funato H, Hobara T, Otsuki K, Yamagata H, McEwen B.S, Watanabe Y.
- Journal Title
  
  J Neurosci 30
  
  Pages: 18-15007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] HDAC4を介した抗うつ薬によるGDNF遺伝子転写制御のメカニズム2012
- Author(s)
  大朏孝治, 内田周作, 芳原輝之, 山形弘隆, 渡邉義文
- Organizer
  第34回生物学的精神医学会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Data Source
  KAKENHI-PROJECT-23791336
[Presentation] The mechanism of GDNF transcriptional regulation by antidepressants through HDAC42012
- Author(s)
  Koji Otsuki, Shusaku Uchida, Hirotaka Yamagata and Yoshifumi Watanabe
- Organizer
  第34回日本神経科学会
- Place of Presentation
  神戸国際会議場(神戸)
- Year and Date
  2012-09-30
- Data Source
  KAKENHI-PROJECT-23791336
[Presentation] Epigenetic mechanisms of GDNF expression involved in the stress vulnerability and depression2011
- Author(s)
  Koji Otsuki, Shusaku Uchida, Teruyuki Hobara, Hirotaka Yamagata and Yoshifumi Watanabe
- Organizer
  第32回内籐財団コンファレンス
- Place of Presentation
  八ヶ岳ロイヤルホテル(山梨)
- Year and Date
  2011-10-19
- Data Source
  KAKENHI-PROJECT-23791336
[Presentation] Epigenetic regulation in depression2011
- Author(s)
  Koji Otsuki, Shusaku Uchida, Teruyuki Hobara, Hirotaka Yamagata and Yoshifumi Watanabe
- Organizer
  第41回日本神経精神薬理学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23791336
[Presentation] Antidepressants increase GDNF gene transcription through the histone modifications by HDAC42010
- Author(s)
  Otsuki K, Uchida S, Yamagata H, Watanabe Y
- Organizer
  Neuroscience 2010, SfN' s 40th annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] Epigenetic regulation in depression2010
- Author(s)
  Koji Otsuki
- Organizer
  第32回日本生物学的精神医学会
- Place of Presentation
  リーガロイヤルホテル小倉(シンポジスト)
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressants increase GDNF gene transcription through the histone modifications by2010
- Author(s)
  Koji Otsuki
- Organizer
  第33回日本神経科学会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressants increase GDNF gene transcription through the histone modifications by HDAC42010
- Author(s)
  Otsuki k.
- Organizer
  北米神経科学会 Neuroscience
- Place of Presentation
  San Diego Convention Center,USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressants increase GDNF gene transcription through the histone modifications by HDAC42010
- Author(s)
  Otsuki k.
- Organizer
  第33回日本神経科学会
- Place of Presentation
  神戸コンベンションセンター,兵庫
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressants increase GDNF gene transcription through the histone modifications by2010
- Author(s)
  Koji Otsuki
- Organizer
  北米神経科学会(Neuroscience 2010)
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Epigenetic regulation in depression.2010
- Author(s)
  Otsuki k.
- Organizer
  第32回日本生物学的精神医学会シンポジウム
- Place of Presentation
  リーガロイヤルホテル小倉,福岡
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] 抗うつ薬はヒストンアセチル化を介してGDNF遺伝子の転写活性を増加させる2009
- Author(s)
  大朏孝治
- Organizer
  第31回日本生物学的精神医学会
- Place of Presentation
  国立京都国際会館,京都
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressants increase transcriptional activity of GDNF gene via the histone modification2009
- Author(s)
  Otsuki K, Uchida S, Watanabe Y
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] Antidepressant drugs increase transcriptional activity of GDNF gene via the histone modification.2009
- Author(s)
  Otsuki k.
- Organizer
  第32回日本神経科学会
- Place of Presentation
  名古屋国際会議場,愛知
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressants increase tr anscriptional activity of GDNF gene via the histone deacetylase2009
- Author(s)
  Koji Otsuki
- Organizer
  Neuroscience 2009
- Place of Presentation
  McCormick Place Convention Center, Chicago, U.S.A.
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PROJECT-21591519
[Presentation] 抗うつ薬はヒストンアセチル化を介してGDNF遺伝子の転写活性を増加させる2009
- Author(s)
  大朏孝治
- Organizer
  第39回日本神経精神薬理学会
- Place of Presentation
  京都国立京都国際会館
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressant drugs increase transcriptional activity of GDNF gene via the histone modification.2009
- Author(s)
  Otsuki k.
- Organizer
  北米神経科学会 Neuroscience
- Place of Presentation
  McCormik Place convention center,USA
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressant drugs increase transcriptional activity of GDNF gene via the histone modification2009
- Author(s)
  Koji Otsuki
- Organizer
  第32回日本神経科学会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] 抗うつ薬はヒストンアセチル化を介してGDNF遺伝子の転写活性を増加させる2009
- Author(s)
  大朏孝治
- Organizer
  第39回日本神経精神薬理学会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] 抗うつ薬はヒストンアセチル化を介してGDNF遺伝子の転写活性を増加させる2009
- Author(s)
  大朏孝治
- Organizer
  第31回日本生物学的精神医学会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Antidepressant drugs increase transcriptional activity of GDNF gene via the histone modification2009
- Author(s)
  Koji Otsuki
- Organizer
  北米神経科学会(Neuroscience 2009)
- Place of Presentation
  米国シカゴ、McComlik Place convention center
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21791134
[Presentation] Reduced hippocampal gray-matter volumes in patients with late-life depression
- Author(s)
  Kenichiro Harada, Koji Matsuo, Mami Nakashima, Fumihiro Higuchi, Naoko Higuchi, Tomohiko Shibata, Masayuki Nakano, Koji Otsuki, Toshio Watanuki, Matakazu Furukawa, Hirotaka Yamagata, Toshio Matsubara, Naofumi Matsunaga, Yoshifumi Watanabe:
- Organizer
  Society of Biological Psychiatry 69th Annual Meeting
- Place of Presentation
  New York, USA
- Year and Date
  2014-05-10 – 2014-05-13
- Data Source
  KAKENHI-PROJECT-24591716
[Presentation] Epigenetic regulation in depression
- Author(s)
  Koji Otsuki, Shusaku Uchida, Teruyuki Hobara, Hirotaka Yamagata and Yoshifumi Watanabe
- Organizer
  第41回日本神経精神薬理学会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23791336
[Presentation] 高齢うつ病の脳構造学的異常
- Author(s)
  原田健一郎、松尾幸治、中島麻美、下地啓五、柴田朋彦、樋口文宏、樋口尚子、中野雅之、芳原輝之、大朏孝治、綿貫俊夫、山形弘隆、松原敏郎、上田克彦、古川又一、松永尚文、渡邉義文
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会合同年会
- Place of Presentation
  奈良県文化会館、奈良市
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24591716

1. MATSUO Koji (00292912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. MATSUBARA Toshio (60526896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. UCHIDA Shusaku (10403669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. YAMGATA Hirotaka (10549934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. WATANUKI Toshio (80610865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 江頭一輝 (90437624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 渡辺義文 (90182964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. 橋岡禎征 (00622523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 松田孟士 (00804759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Otuki Kouji 大朏 孝治

OTSUKI Koji 大朏 孝治

Research Projects

Research Products

Co-Researchers

Comprehensive elucidation of anti-neuroinflammatory effects of electroconvulsive treatment

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Disrupted cortico-limbic network and molecular mechanism in bipolar disorder

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A study of new drug development of target of histone deacetylasePrincipal Investigator

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Neural correlates of plasma acylated ghrelin level in individuals with mood disorders

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Analysis of the epigenetic regulation in the mechanism of antidepressants.Principal Investigator

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[Book] 精神疾患診断のための脳形態・機能検査法2012

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[Book] 末梢白血球に発現している遺伝子と気分障害, 精神疾患診断のための脳形態・機能検査法2011

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[Journal Article] Improvement in both severe obsessive-compulsive disorder and refractory tardive dystonia following electroconvulsive therapy: A case report2022

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[Journal Article] Effect of Ninjin’yoeito on Lipopolysaccharide-Induced Depressive-Like Behavior and Glial Activation in the Hippocampus2022

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[Journal Article] The alteration of hypoxia inducible facter-1 (HIF-1) and its target genenes in mood disorder patients2013

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[Journal Article] うつ病におけるエピジェネティクス2012

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NAID

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[Journal Article] Altered sirtuin deacetylase gene expression in patients with a mood disorder2012

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[Journal Article] 気分障害のバイオマーカー開発、とくに白血球での遺伝子発現からみた気分障害の状態診断、亜型分類2012

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NAID

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[Journal Article] State-dependent changes in the expression of DNA methyltransferases in mood disorder patients2012

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[Journal Article] ヒストン脱アセチル化酵素阻害剤の早期抗うつ効果発現における分子機構の解析2012

Author(s)

Otuki Kouji 大朏孝治

OTSUKI Koji 大朏孝治