Kondo Jiro 近藤次郎

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KONDO Jiro 近藤次郎

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Researcher Number	10546576
Other IDs	https://orcid.org/0000-0002-5682-3685
Affiliation (Current)	2025: 上智大学, 理工学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 上智大学, 理工学部, 教授 2015 – 2021: 上智大学, 理工学部, 准教授 2011 – 2014: 上智大学, 理工学部, 助教
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related Except Principal Investigator Basic Section 34010:Inorganic/coordination chemistry-related / Inorganic chemistry / Functional materials/Devices
Keywords	Principal Investigator ドラッグデザイン / Ｘ線結晶解析 / RNA / X線結晶解析 / リボソーム / 抗生物質 / 構造生物学 / 生物模倣科学 / 核酸医薬品 / 分子認識 … More / 薬学 / 感染症 / 核酸 / ウィルス / インフルエンザ / アミノグリコシド / 抗ウイルス薬 / インフルエンザウイルス / ナンセンス変異型遺伝性疾患 / 薬剤耐性菌 … More Except Principal Investigator matallo-base pair / DNA nanowire / ナノワイヤー / metal nanocluster / DNA synthesis / Oligonucleotide / Metal nanocluster / Metallo-base pair / metallo base pair / oligonucleotide / DNA architecture / nanocluster / metallo-base pair / DNA二重鎖 / 光連結法 / DNAナノワーヤー / 金属イオン－核酸 / 単分子導電性 / Hg-DNA wire / Ag-DNA wire / DNA超分子 / 結晶構造 / DNAナノワイヤー / 金属含有DNA二重鎖 / オリゴヌクレオチド合成 / 金属錯体 / 超分子 / Crystal structure / DNA/RNA synthesis / Molecule Conductance / crystal structure / metallo-base pairs / metallo-DNA/RNA / Molecular architecture / DNA Supermolecule / ポリメラーゼ / 除去 / 検出 / DNA合成酵素 / 等温滴定型カロリメトリー / 結晶解析 / NMR / 機能性核酸 / 金属含有DNA / 水銀イオン / 水銀イオン検出 / 多次元多核種NMR法 / 結晶構造解析 / 水銀イオンの検出 / 水銀イオンの除去 / 環境浄化 Less

Development of novel nucleic acid therapeutics by structural biomimeticsPrincipal Investigator
- Principal Investigator
  
  近藤次郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Sophia University
Nucleic Acid-Metal Complexes: Preparation, structure analysis, characterization of metal-DNA wires and metal nanocluster-DNA complexes.
- Principal Investigator
  
  小野晶
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 34010:Inorganic/coordination chemistry-related
- Research Institution
  Kanagawa University
Structural study of the influenza virus genome RNA and development of anti-flu medicinesPrincipal Investigator
- Principal Investigator
  
  Jiro Kondo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sophia University
Synthesis and characterization of metallo-DNA nanowire with infinite, uninterrupted one-dimensional metal ions array
- Principal Investigator
  
  Ono Akira
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Inorganic chemistry
- Research Institution
  Kanagawa University
Elucidation of pharmacological effects of antibiotics against genetic diseases caused by nonsense mutations and development of new therapeutic agentsPrincipal Investigator
- Principal Investigator
  
  Kondo Jiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sophia University
Development of DNA based heavy metal ions removing membranes and nanowires-structures, properties, applications.
- Principal Investigator
  
  Ono Akira
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional materials/Devices
- Research Institution
  Kanagawa University
Structural studies on antibiotic-resistance mechanisms and their application to drug designPrincipal Investigator
- Principal Investigator
  
  KONDO Jiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sophia University

[Book] Claude Sauter & Benoît Masquida. RNA crystallization. In Roland K. Hartmann, Albrecht Bindereif, Astrid Schon & Eric Westhof (eds.), Handbook of RNA Biochemistry, second edition2014
- Author(s)
  Jiro Kondo
- Publisher
  Wiley VHC
- Data Source
  KAKENHI-PROJECT-23790054
[Book] structural decoding of inhibitors targeting the ribosomal decoding A site. In Claudio O. Gualerzi, Letizia Brandi, Attilio Fabbretti & Cynthia L. Pon (eds.), Antibiotics : Targets, Mechanisms and Resistance2013
- Author(s)
  Jiro Kondo & Eric Westhof
- Publisher
  Wiley VHC
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] A Novel AgI -DNA Rod Comprising a One-Dimensional Array of 11 Silver Ions within a Double Helical Structure2022
- Author(s)
  T. Atsugi, A. Ono,* M. Tasaka, N. Eguchi, S. Fujiwara, and J. Kondo
- Journal Title
  
  Angew. Chem. Int. Ed.,
  
  Volume: 61 Issue: 31
- DOI
  10.1002/anie.202204798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21123
[Journal Article] Effect of cytosine-Ag+-cytosine base pairing on the redox potential of the Ag+/Ag couple and the chemical reduction of Ag+ to Ag by tetrathiafulvalene2021
- Author(s)
  Takenori Dairaku, Rika Kawai, Teppei Kanaba, Tetsuya Ono, Kentaro Yoshida, Hajime Sato, Kanako Nozawa-Kumada, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka and Yoshitomo Kashiwagi
- Journal Title
  
  Dalton Transactions
  
  Volume: - Issue: 22 Pages: 7633-7639
- DOI
  10.1039/d1dt00975c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K14597, KAKENHI-PROJECT-19K05705, KAKENHI-PROJECT-23K21123
[Journal Article] Crystal structure of a DNA duplex cross-linked by 6-thioguanine-6-thioguanine disulfides: reversible formation and cleavage catalyzed by Cu(II) ions and glutathione2019
- Author(s)
  Akira Ono, Takahiro Atsugi, Misato Goto, Hisao Saneyoshi, Takahito Tomori, Kohji Seio, Takenori Dairaku and Jiro Kondo
- Journal Title
  
  RSC Adv
  
  Volume: 9 Issue: 40 Pages: 22859-22862
- DOI
  10.1039/c9ra03515j
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03033
[Journal Article] Novel DNA helical wire containing Hg(II) mediated T:T and T:G pairs2019
- Author(s)
  Akira Ono, Hiroki Kanazawa, Hikari Ito, Misato Goto, Koudai Nakamura, Hisao Saneyoshi, Jiro Kondo
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 58 Issue: 47 Pages: 16835-16838
- DOI
  10.1002/anie.201910029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03033
[Journal Article] Conformational adaptation of UNCG loops upon crowding2019
- Author(s)
  Meyer Melanie、Walbott Helene、Olieric Vincent、Kondo Jiro、Costa Maria、Masquida Benoit
- Journal Title
  
  RNA
  
  Volume: 25 Issue: 11 Pages: 1522-1531
- DOI
  10.1261/rna.072694.119
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Journal Article] Structural Bases for the Fitness Cost of the Antibiotic-Resistance and Lethal Mutations at Position 1408 of 16S rRNA2019
- Author(s)
  Kondo Jiro、Koganei Mai
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 1 Pages: 159-159
- DOI
  10.3390/molecules25010159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08248
[Journal Article] Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside2018
- Author(s)
  Kanazawa Hiroki、Saavedra Oscar M.、Maianti Juan Pablo、Young Simon A.、Izquierdo Luis、Smith Terry K.、Hanessian Stephen、Kondo Jiro
- Journal Title
  
  ChemMedChem
  
  Volume: 13 Issue: 15 Pages: 1541-1548
- DOI
  10.1002/cmdc.201800166
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Journal Article] Crystal structure of a DNA duplex containing four Ag(I) ions in consecutive dinuclear Ag(I)-mediated base pairs: 4-thiothymine-2Ag(I)-4-thiothymine2017
- Author(s)
  Akira Ono, Toru Sugawara, Hisao Saneyoshi, Jiro Kondo
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 86 Pages: 11747-11750
- DOI
  10.1039/c7cc06153f
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03033
[Journal Article] A metallo-DNA nanowire with uninterrupted one-dimensional silver array2017
- Author(s)
  Jiro Kondo, Yoshinari Tada, Takenori Dairaku, Yoshikazu Hattori, Hisao Saneyoshi, Akira Ono, Yoshiyuki Tanaka,
- Journal Title
  
  Nature Chemistry
  
  Volume: 9 Issue: 10 Pages: 956-960
- DOI
  10.1038/nchem.2808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03033, KAKENHI-PROJECT-15K13734
[Journal Article] A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA2017
- Author(s)
  Kanazawa Hiroki、Baba Fumika、Koganei Mai、Kondo Jiro
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 45 Issue: 21 Pages: 12529-12535
- DOI
  10.1093/nar/gkx882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08248
[Journal Article] DNAナノメディシンのStructure-Based Design2016
- Author(s)
  近藤次郎
- Journal Title
  
  月刊化学工業
  
  Volume: 27 Pages: 28-36
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] 核酸構造生物学の最前線2016
- Author(s)
  近藤次郎
- Journal Title
  
  SOPHIA SCI-TECH 上智大学理工学振興会会報
  
  Volume: 27 Pages: 2-7
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] Structures, physicochemical properties, and applications of T-HgII-T, C-AgI-C, and other metallo-base-pairs.2015
- Author(s)
  Yoshiyuki Tanaka, Jiro Kondo, Vladimir Sychrovsky, Jakub Sebera, Takenori Dairaku, Hisao Saneyoshi, Hidehito Urata, Hidetaka Torigoe and Akira Ono
- Journal Title
  
  Chem. Commun.
  
  Volume: 51 Issue: 98 Pages: 17313-17360
- DOI
  10.1039/c5cc02693h
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05574, KAKENHI-PROJECT-15K13734, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-14J03684, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-26288084
[Journal Article] Exploring a DNA sequence for the three-dimensional structure determination of a silver(I)-mediated C-C base pair in a DNA duplex by 1H NMR spectroscopy2015
- Author(s)
  Takenori Dairaku, Kyoko Furuita, Hajime Sato, Yoshinori Kondo, Chojiro Kojima, Akira Ono and Yoshiyuki Tanaka
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: 34 Issue: 12 Pages: 877-900
- DOI
  10.1080/15257770.2015.1088160
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K13734, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-14J03684, KAKENHI-PROJECT-26650018, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-26291013
[Journal Article] Crystal Structure of the Bacterial A Site in Complex with β-Fluoro Neomycin Analog2015
- Author(s)
  Hiroki Kanazawa, Juan Pablo Maianti, Stephen Hanessian, Jiro Kondo
- Journal Title
  
  Photon Factory Activity Report 2014
  
  Volume: 32 Pages: 232-232
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] High-resolution crystal structure of AgI-RNA hybrid duplex containing Watson-Crick-like C-AgI-C metallo-base pairs2015
- Author(s)
  Jiro Kondo, Yoshinari Tada, Takenori Dairaku, Hisao Saneyoshi, Itaru Okamoto, Yoshiyuki Tanaka, Akira Ono
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 54 Issue: 45 Pages: 13323-13326
- DOI
  10.1002/anie.201507894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K13734, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-14J03684, KAKENHI-PROJECT-24310163
[Journal Article] 核酸構造生物学の創薬・ナノ材料科学への展開2015
- Author(s)
  近藤次郎
- Journal Title
  
  日本化学会・生体機能関連化学部会ニュースレター
  
  Volume: 29 Pages: 15-18
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] Crystal structure of the bacterial A site in complex with axial 4’-fluoro neomycin analog2015
- Author(s)
  Hiroki Kanazawa, Stephen Hanessian, Jiro Kondo
- Journal Title
  
  Photon Factory Activity Report 2014
  
  Volume: 32 Pages: 231-231
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] Crystallographic studies of the ribosomal A-site molecular switches by using model RNA oligomers2015
- Author(s)
  Jiro Kondo
- Journal Title
  
  Nucleic Acid Crystallography: Methods and Protocols (Methods in Molecular Biology)
  
  Volume: 1320 Pages: 315-327
- DOI
  10.1007/978-1-4939-2763-0_20
- ISBN
  9781493927623, 9781493927630
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] ノンコーディング核酸の「動き」を見て「働き」を理解する2015
- Author(s)
  近藤次郎
- Journal Title
  
  日本RNA学会会報
  
  Volume: 36 Pages: 12-14
- Open Access
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] Direct Detection of the Mercury-Nitrogen Bond in the Thymine-HgII-Thymine Base-pair with 199Hg NMR Spectroscopy2015
- Author(s)
  Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Sebera, Daichi Yamanaka, Hiroyuki Otaki, Shoko Kikkawa, Yoshinori Kondo, Ritsuko Katahira, F. Matthias Bickelhaupt, Celia Fonseca Guerra, Akira Ono, Vladimir Sychrovsky, Chojiro Kojima and Yoshiyuki Tanaka
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 40 Pages: 8488-8491
- DOI
  10.1039/c5cc02423d
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K13734, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-14J03684, KAKENHI-PROJECT-26650018, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-26291013
[Journal Article] The structure of metallo-DNA with consecutive T-HgII-T base-pairs explains positive entropy for the metallo-base-pair formation2014
- Author(s)
  Yamaguchi H
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 42 Issue: 6 Pages: 4094-4099
- DOI
  10.1093/nar/gkt1344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370053, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-24657074
[Journal Article] Synthesis, broad spectrum antibacterial activity, and X-ray co-crystal structure of the decoding bacterial ribosomal A-site with 4'-deoxy-4'-fluoro neomycin analogs2014
- Author(s)
  Stephen Hanessian, Oscar M. Saavedra, Miguel A. Vilchis-Reyes, Juan P. Maianti, Hiroki Kanazawa, Paola Dozzo, Rowena D. Matias, Alisa Serio, Jiro Kondo.
- Journal Title
  
  Chemical Science
  
  Volume: 5 Issue: 12 Pages: 4621-4632
- DOI
  10.1039/c4sc01626b
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] Hg<sup>2+</sup>-Trapping Beads: Hg<sup>2+</sup>-Specific Recognition through Thymine–Hg(II)–Thymine Base Pairing2014
- Author(s)
  栗山光博、他12名
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 7 Pages: 709-712
- DOI
  10.1248/cpb.c13-00918
- NAID
  130004053812
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J07758, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-24590004, KAKENHI-PROJECT-25460002
[Journal Article] Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs2014
- Author(s)
  Juan Pablo Maianti, Hiroki Kanazawa, Paola Dozzo, Rowena D. Matias, Lee Ann Feeney, Eliana S. Armstrong, Darin J. Hildebrandt, Timothy R. Kane, Micah J. Gliedt, Adam A. Goldblum, Martin S. Linsell, James B. Aggen, Jiro Kondo, Stephen Hanessian.
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 9 Issue: 9 Pages: 2067-2073
- DOI
  10.1021/cb5003416
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860025
[Journal Article] Crystal structure of metallo-DNA duplex containing consecutive Watson-Crick-like T-Hg(II)-T base pairs2014
- Author(s)
  J. Kondo, T. Yamada, C. Hirose, I. Okamoto, Y. Tanaka, A. Ono
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 53 Issue: 9 Pages: 2385-2388
- DOI
  10.1002/ange.201309066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24245037
[Journal Article] Identification of the molecular attributes required for aminoglycoside activity against Leishmania2013
- Author(s)
  Moran Shalev, Jiro Kondo, Dmitry Kopelyanskiy, Charles L. Jaffe, Noam Adir, Timor Baasov
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 110 Issue: 33 Pages: 13333-1338
- DOI
  10.1073/pnas.1307365110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] Formation of the T-HgII-T Metal-Mediated DNA Base Pair; Proposal and Theoretical Calculation of the Reaction Pathway2013
- Author(s)
  Sebera J
- Journal Title
  
  Chemistry
  
  Volume: 19 Issue: 30 Pages: 9884-9894
- DOI
  10.1002/chem.201300460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370053, KAKENHI-PROJECT-24245037, KAKENHI-PROJECT-24310163, KAKENHI-PROJECT-24657074
[Journal Article] リボソームの分子進化 : AサイトRNA分子スイッチの動きからの考察2013
- Author(s)
  近藤次郎
- Journal Title
  
  実験医学増刊号
  
  Volume: 31 Pages: 1011-1017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] Crystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sites2013
- Author(s)
  Jiro Kondo, Mai Koganei, Juan Pablo Maianti,Vu Linh Ly, Stephen Hanessian
- Journal Title
  
  ChemMedChem
  
  Volume: 8 Issue: 5 Pages: 733-739
- DOI
  10.1002/cmdc.201200579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] リボソームの分子進化：AサイトRNA分子スイッチの動きからの考察2013
- Author(s)
  近藤次郎
- Journal Title
  
  実験医学増刊号
  
  Volume: 31 Pages: 1011-1017
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] Crystal structures of the bacterial and protozoal A sites in complex with 6'-hydroxysisomicin2013
- Author(s)
  Jiro Kondo, Mai Koganei, Juan Pablo Maianti, Vu Linh Ly, Stephen Hanessian
- Journal Title
  
  Photon Factory Activity Report 2012
  
  Volume: 30 Pages: 285-285
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] Crystal structures of the bacterial A site in complex with sisomicin2013
- Author(s)
  Jiro Kondo, Mai Koganei, Tomoko Kasahara
- Journal Title
  
  Photon Factory Activity Report 2012
  
  Volume: 30 Pages: 286-286
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] Crystal structures of the bacterial A1408G-mutant A site with and without geneticin2012
- Author(s)
  Jiro Kondo
- Journal Title
  
  Photon Factory Activity Report 2011
  
  Volume: 29 Pages: 339-339
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] Crystal structure and specific binding mode of sisomicin to the bacterial ribosomal decoding site2012
- Author(s)
  Jiro Kondo, Mai Koganei, Tomoko Kasahara
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 3 Issue: 9 Pages: 741-744
- DOI
  10.1021/ml300145y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790054
[Journal Article] A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA and for the antiprotozoal activity of aminoglycosides2012
- Author(s)
  Jiro Kondo
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 51 Issue: 2 Pages: 465-468
- DOI
  10.1002/anie.201106084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790054
[Patent] DNAー金属ハイブリッドナノワイヤーおよびその製造方法2016
- Inventor(s)
  近藤次郎、多田能成
- Industrial Property Rights Holder
  学校法人上智学院
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-062547
- Filing Date
  2016-03-25
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] Application of structural motifs found in ribosomal RNA as nucleic acids therapeutics2023
- Author(s)
  Teppei Chinone, Jiro Kondo
- Organizer
  RNA 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04948
[Presentation] Design of model molecules for X-ray crystallography for RNA-targeted drug discovery2023
- Author(s)
  Jiro Kondo, Akira Sato, Moena Takahashi, Yusuke Inoue
- Organizer
  IUCr 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04948
[Presentation] RNAターゲット創薬のための立体構造解析・医薬品デザインの技術2023
- Author(s)
  近藤次郎
- Organizer
  ファーマラボEXPO 第５回アカデミックフォーラム
- Data Source
  KAKENHI-PROJECT-23K04948
[Presentation] 創薬標的としてのRNA立体構造モチーフ2023
- Author(s)
  近藤次郎
- Organizer
  CBI学会2023年大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K04948
[Presentation] Effects of heavy metal ions on the RNA structures and functions2023
- Author(s)
  Miyu Ozawa, Chiharu Suzuki, Akari Tsudura, Yuriko Uchida, Yoshinari Tada, Kenta Kubodera, Tom Yamada, Akira Ono, Jiro Kondo
- Organizer
  RNA 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K04948
[Presentation] Effects of mercury and silver ions on the RNA structures and functions2022
- Author(s)
  Miyu Ozawa, Chiharu Suzuki, Akari Tsudura, Yuriko Uchida, Yoshinari Tada, Kenta Kubodera, Tom Yamada, Akira Ono, Jiro Kondo
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21123
[Presentation] Synthesis, purification, and spectroscopic properties of reduced DNA-Ag(I) nanowires2022
- Author(s)
  Hee Ju Park, Natsumi Eguchi, Jiro Kondo, Takahiro Atsugi, Akira Ono
- Organizer
  The 49th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21123
[Presentation] 短鎖 Ag-DNAワイヤーの溶液中での形成と結晶構造2021
- Author(s)
  厚木隆裕、近藤次郎、小野晶
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-23K21123
[Presentation] 短鎖 Ag-DNAワイヤーの溶液中での形成と結晶構造2021
- Author(s)
  厚木隆裕、近藤次郎、小野晶
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Novel structures of non-natural nucleic acid duplexes2021
- Author(s)
  Akira Ono, Chinatsu Yazawa, Takahiro Atsug, Jiro Kondo
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21123
[Presentation] Preparation and structure analysis of oligonucleotide-metal ion complexes2021
- Author(s)
  Takahiro Atsugi, Ryo Yoshikawa, Jiro Kondo, Akira Ono
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21123
[Presentation] Synthesis and purification of reduced DNA-silver hybrid nanowires2021
- Author(s)
  Natsumi Eguchi, Takahiro Atsugi, Takenori Dairaku, Yoshiyuki Tanaka, Akira Ono, Jiro Kondo
- Organizer
  The 48th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21123
[Presentation] DMSO中におけるシチジン/AgI (2:1)錯体の還元電位2020
- Author(s)
  川井李佳、大樂武範、小野哲也、吉田健太郎、近藤次郎、小野晶、田中好幸、柏木良友
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Structural study of the bulged-G motif observed in functional RNAs2019
- Author(s)
  Sao Sekiguchi, Jiro Kondo
- Organizer
  AsCA2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] Structural study of the kink-turn motif2019
- Author(s)
  Miki Nagashima, Jiro Kondo
- Organizer
  ISNAC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] Novel Structures of modified oligonucleotides and oligonucleotide-metal complexes Akira Ono, Takahiro Atsugi, Hikari Ito, Misato Goto, Hisao Saneyoshi, Jiro Kondo2019
- Author(s)
  Akira Ono, Takahiro Atsugi, Hikari Ito, Misato Goto, Hisao Saneyoshi, Jiro Kondo
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Structural study of the GNRA tetraloop and its receptor motif observed in functional RNAs2019
- Author(s)
  Asaki Hayasaka, Jiro Kondo
- Organizer
  AsCA2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] サイクリックボルタンメトリーを用いたメタロ塩基対の酸化還元特性の解析2019
- Author(s)
  奥山まりん, 大樂武範, 小野哲也, 吉田健太郎, 金場哲平, 佐藤一, 近藤次郎, 小野晶, 田中好幸, 柏木良友
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] X-Ray analyses of natural and modified RNA kink-turn motifs2019
- Author(s)
  Miki Nagashima, Jiro Kondo
- Organizer
  AsCA2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] X-Ray analyses of the ribosomal RNA A site molecular switch with fluorescent nucleobase 2-aminopurine2019
- Author(s)
  Kotomi Ishikawa, Jiro Kondo
- Organizer
  AsCA2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] Preparations and structure elucidations of metallo-DNAs: DNA　nanowire with uninterrupted one-dimensional silver ion array2018
- Author(s)
  Akira Ono, Hisao Saneyoshi, Jiro Kondo, Yoshiyuki Tanaka
- Organizer
  23th International Round Table on Nucleosides, Nucleotides and Nucleic Acids
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Structure-based design of a eukaryote-selective aminoglycoside2018
- Author(s)
  Kanazawa Hiroki、Saavedra Oscar M.、Maianti Juan Pablo、Young Simon A.、Izquierdo Luis、Smith Terry K.、Hanessian Stephen、Kondo Jiro
- Organizer
  ISNAC2018 (The 45th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] 多核NMR 分光法によるメタロ塩基対の構造決定2018
- Author(s)
  大樂武範, 古板恭子, 佐藤一, 小野哲也, 吉田健太郎, 柏木良友, 中島勝幸, 近藤次郎, 根東義則, 小野晶, 児嶋長次郎, 田中好幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] リボソームRNA分子スイッチの立体構造に与える銀・水銀イオンの影響の解析2018
- Author(s)
  長嶋未来、鈴木千晴、廿樂明里、内田ゆり子、窪寺健太、小野晶、近藤次郎
- Organizer
  日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] Thermodynamic Properties of the Specific Binding of 4-Thiothymine to Each of Thymine and Cytosine in Mismatched Duplex DNA by Different Metal Ions2018
- Author(s)
  Ayami Yaguchi, Akira Ono, Jiro Kondo, Hidetaka Torigoe
- Organizer
  第45回国際核酸化学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Effects of Hg(II) and Ag(I) on the structure of the rRNA A site molecular switches2018
- Author(s)
  Miki Nagashima, Chiharu Suzuki, Akari Tsudura, Yuriko Uchida, Kenta Kubodera, Akira Ono, Jiro Kondo
- Organizer
  ISNAC2018 (The 45th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] Effects of Hg(II) and Ag(I) on the structure of the rRNA A site molecular switches2018
- Author(s)
  Miki Nagashima, Chiharu Suzuki, Akari Tsudura, Yuriko Uchida, Kenta Kubodera, Akira Ono, Jiro Kondo
- Organizer
  第45回国際核酸化学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Thermodynamic Properties of the Specific Binding between Metal Ion and Mismatched Base Pairs Involving 5-Hydroxyuracil or 5-Hydroxycytosines2018
- Author(s)
  Fumihiro Arakawa, Ayami Yaguchi, Akira Ono, Jiro Kondo, Hidetaka Torigoe
- Organizer
  第45回国際核酸化学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Crystal structures of DNA and RNA duplexes containing gold- and copper-mediated base pairs2018
- Author(s)
  Erika Iwase, Yoshinari Tada, Akira Ono, Jiro Kondo
- Organizer
  第45回国際核酸化学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] リボソームRNA分子スイッチの立体構造に与える銀・水銀の影響の解析2018
- Author(s)
  長嶋未来、鈴木千晴、廿樂明里、内田ゆり子、窪寺健太、小野晶、近藤次郎
- Organizer
  NART Meeting 2018 -未来核酸テクノロジー研究会-
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] Structure analyses of a novel DNA helical wire containing Hg(II) -mediated T:T and T:G base pairs2018
- Author(s)
  Akira Ono, Hiroki Kanazawa, Hikari Ito, Misato Goto, Hisao Saneyoshi, Jiro Kondo
- Organizer
  第45回国際核酸化学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] 金・銅仲介塩基対を含むRNAのX線結晶解析2017
- Author(s)
  岩瀬襟伽、多田能成、近藤次郎
- Organizer
  平成29年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Crystallographic studies of metallo-DNA nanostructures2017
- Author(s)
  近藤次郎
- Organizer
  Symposium on Frontier of Biofunctional Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Crystal structures of oligonucleotides having metallo-base pairs2017
- Author(s)
  Akira Ono, Toru Sugawara, Hikari Ito, Misato Goto, Hisao Saneyoshi, Jiro Kondo
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Characterization of DNA duplexes containing metal ion mediated base pairs2017
- Author(s)
  Akira Ono, Hisao Saneyoshi, Jiro Kondo, Yoshiyuki Tanaka
- Organizer
  17th Symposium on Chemistry of Nucleic Acid Components
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Crystal structure of the human ribosomal decoding A site in complex with G418 possessing readthrough activity2017
- Author(s)
  Hiroki Kanazawa、Nao Tsurumi、Jiro Kondo
- Organizer
  ISNAC2017 (The 44th International Symposium on Nucleic Acids Chemistry)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08248
[Presentation] DNA構造バイオナノテクノロジー2017
- Author(s)
  近藤次郎
- Organizer
  平成29年度日本結晶学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03033
[Presentation] Crystal structures of the bacterial ribosomal RNA in complex with fluorinated aminoglycosides2016
- Author(s)
  Hiroki Kanazawa, Juan P. Maianti, Stephen Hanessian, Jiro Kondo
- Organizer
  ISNAC2016
- Place of Presentation
  熊本大学黒髪キャンパス（熊本市）
- Year and Date
  2016-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] DNAナノマテリアル・ナノメディシンのStructure-Based Design2016
- Author(s)
  近藤次郎
- Organizer
  JST 新技術説明会
- Place of Presentation
  JST東京本部別館ホール（東京都千代田区）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] Interactions between the bacterial ribosomal RNA and fluorinated aminoglycosides2016
- Author(s)
  Hiroki Kanazawa, Juan P. Maianti, Stephen Hanessian, Jiro Kondo
- Organizer
  RNA2016
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] RNA-リガンド相互作用の分類2015
- Author(s)
  近藤次郎、Eric Westhof
- Organizer
  GE Life Sciences Day 2015
- Place of Presentation
  パシフィコ横浜会議センター（神奈川県横浜市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] フッ素化アミノグリコシドとリボソームRNAの複合体のX線結晶解析2015
- Author(s)
  金澤宏樹、Juan Pablo Maianti、Stephen Hanessian、近藤次郎
- Organizer
  GE Life Sciences Day 2015
- Place of Presentation
  パシフィコ横浜会議センター（神奈川県横浜市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] Structure of C-Ag(I)-C metallo base pair in RNA duplex2015
- Author(s)
  Yoshinari Tada, Takenori Dairaku, Itaru Okamoto3 Hisao Saneyoshi, Yoshiyuki Tanaka, Akira Ono, Jiro Kondo
- Organizer
  The 42th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Egret Himeji, Himeji
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] フッ素化アミノグリコシドの細菌リボソームRNAとの相互作用2015
- Author(s)
  金澤宏樹、Juan Pablo Maianti、Stephen Hanessian、近藤次郎
- Organizer
  日本核酸医薬学会第１回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] 核酸塩基-アミノ酸相互作用の分類2015
- Author(s)
  近藤次郎、Eric Westhof
- Organizer
  GE Life Sciences Day 2015
- Place of Presentation
  パシフィコ横浜会議センター（神奈川県横浜市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] ストロンチウムイオン結合モチーフを持つ特殊なRNA二重らせんの立体構造2014
- Author(s)
  金澤宏樹、近藤次郎
- Organizer
  物構研サイエンスフェスタ2013
- Place of Presentation
  つくば国際会議場エポカル(つくば市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] ストロンチウムイオン結合モチーフを持つ特殊なRNA二重らせんの立体構造2014
- Author(s)
  金澤宏樹、近藤次郎
- Organizer
  物構研サイエンスフェスタ2013
- Place of Presentation
  つくば国際会議場エポカル（つくば市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Crystal structures of the protozoal cytoplasmic A site in complex with aminoglycosides2013
- Author(s)
  Jiro Kondo, Mai Koganei
- Organizer
  RNA2013 (18th annual meeting of the RNA society)
- Place of Presentation
  スイス・ダボス
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Crystal structures of the protozoal cytoplasmic A site in complex with aminoglycosides. RNA20132013
- Author(s)
  Jiro Kondo, Mai Koganei
- Organizer
  18th annual meeting of the RNA society
- Place of Presentation
  スイス・ダボス
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Crystal Structure of DNA duplex containing two consecutive T-Hg(II)-T base pairs2013
- Author(s)
  Jiro Kondo, Tom Yamada, Chika Hirose, Itaru Okamoto, Yoshiyuki Tanaka, Akira Ono
- Organizer
  The 40th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kanagawa University
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] Theoretical Model of the Reaction Pathway Describing Formation of the T-HgII-T Metal-Mediated DNA Base Pair2013
- Author(s)
  Jakub Sebera, Jaroslav Burda, Michal Straka, Akira Ono, Chojiro Kojima, Yoshiyuki Tanaka, and Vladimir Sychrovsky
- Organizer
  The 40th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kanagawa University
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] ヒト・ミトコンドリアリボソームRNAの結晶多形性と立体構造との相関2013
- Author(s)
  宮崎まい、鉄本環、高橋由紀子、近藤次郎
- Organizer
  平成25年度日本結晶学会年会
- Place of Presentation
  熊本大学(熊本市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] ヒト・ミトコンドリアリボソームRNA の結晶多形性と立体構造との相関2013
- Author(s)
  宮崎まい、鉄本環、高橋由紀子、近藤次郎
- Organizer
  平成25年度日本結晶学会年会
- Place of Presentation
  熊本大学（熊本市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Structure of Ag(I)-mediated C-C base pair determined by hetero-nuclear NMR spectroscopy2013
- Author(s)
  Takenori Dairaku, Itaru Okamoto, Kyoko Furuita, Jakub Sebera, Mathias Bickelhaupt, Shuji Oda1 Daichi Yamanaka, Yoshinori Kondo, Vladimir Sychrovsky, Chojiro Kojima, Akira Ono, Yoshiyuki Tanaka
- Organizer
  The 40th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kanagawa University
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] 細菌リボソームAサイト-シソマイシン複合体のX線結晶解析2012
- Author(s)
  小金井麻衣、笠原朋子、近藤次郎
- Organizer
  第１回リボソームミーティング
- Place of Presentation
  広島大学（東広島市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA2012
- Author(s)
  Jiro Kondo
- Organizer
  The 50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  名古屋大学（名古屋市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] アミノグリコシド系抗生物質に対する薬剤耐性獲得メカニズムの構造基盤2012
- Author(s)
  近藤次郎
- Organizer
  平成24年度日本結晶学会年会
- Place of Presentation
  東北大学(仙台市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] X線結晶解析で見るRNA分子スイッチの「動き」=「働き」2012
- Author(s)
  近藤次郎
- Organizer
  第63回結晶化学研究会
- Place of Presentation
  東京工業大学(東京都)
- Year and Date
  2012-12-22
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] 細菌リボソームAサイト－シソマイシン複合体の結晶構造2012
- Author(s)
  小金井麻衣、笠原朋子、近藤次郎
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] X線結晶解析で見るRNA分子スイッチの「動き」＝「働き」2012
- Author(s)
  近藤次郎
- Organizer
  第63回結晶化学研究会
- Place of Presentation
  東京工業大学（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Towards the structure-based design of antiprozoal agents: crystal structures of aminoglycosides with an unsaturated sugar ring bound to the ribosomal A sites2012
- Author(s)
  Jiro Kondo, Mai Koganei, Tomoko Kasahara, Stephen Hanessian
- Organizer
  ISNAC2012 (The 39th International Symposium on Nucleic Acid Chemistry)
- Place of Presentation
  名古屋大学（名古屋市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] 細菌リボソームAサイト-シソマイシン複合体の結晶構造2012
- Author(s)
  小金井麻衣、笠原朋子、近藤次郎
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  東北大学(仙台市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] 16S rRNAのA1408G変異による薬剤耐性獲得の構造基盤2012
- Author(s)
  近藤次郎
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] 16S rRNAのA1408G変異による薬剤耐性獲得の構造基盤2012
- Author(s)
  近藤次郎
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  東北大学(仙台市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA2012
- Author(s)
  Jiro Kondo
- Organizer
  The 50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  名古屋大学(名古屋市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] アミノグリコシド系抗生物質に対する薬剤耐性獲得メカニズムの構造基盤2012
- Author(s)
  近藤次郎
- Organizer
  平成24年度日本結晶学会年会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] アミノグリコシド系抗生物質に対する耐性獲得メカニズムの構造基盤2012
- Author(s)
  近藤次郎
- Organizer
  第１回リボソームミーティング
- Place of Presentation
  広島大学（東広島市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] アミノグリコシド系抗生物質に対する耐性獲得メカニズムの構造基盤2012
- Author(s)
  近藤次郎
- Organizer
  第1回リボソームミーティング
- Place of Presentation
  広島大学(東広島市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Towards the structure-based design of antiprozoal agents : crystal structures of aminoglycosides with an unsaturated sugar ring bound to the ribosomal A sites. ISNAC20122012
- Author(s)
  Jiro Kondo, Mai Koganei, Tomoko Kasahara, Stephen Hanessian
- Organizer
  The 39th International Symposium on Nucleic Acid Chemistry
- Place of Presentation
  名古屋大学(名古屋市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] 細菌リボソームAサイト-シソマイシン複合体のX線結晶解析2012
- Author(s)
  小金井麻衣、笠原朋子、近藤次郎
- Organizer
  第1回リボソームミーティング
- Place of Presentation
  広島大学(東広島市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Structural basis for antibiotic resistance conferred by an A1408G mutation in 16S rRNA, ISNAC20112011
- Author(s)
  Jiro Kondo
- Organizer
  The 38th International Symposium on Nucleic Acid Chemistry
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Structural basis for antibiotic resistance conferred by an A1408G mutation in 16S rRNA2011
- Author(s)
  Jiro Kondo
- Organizer
  ISNAC2011 (The 38th International Symposium on Nucleic Acid Chemistry)
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23790054
[Presentation] Crystal structure of RNA duplex containing strontium ion binding motif
- Author(s)
  Hiroki Kanazawa, Jiro Kondo
- Organizer
  ISNAC2014 (The 41th International Symposium on Nucleic Acid Chemistry)
- Place of Presentation
  北九州国際会議場（北九州市）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] Syntheses and characterizations of DNA duplexes having metal ion mediated base pairs
- Author(s)
  Akira Ono, Itaru Okamoto, Hidehito Urata, Hidetake Torigoe, Hisao Saneyoshi, Jiro Kondo, Yoshiyuki Tanaka
- Organizer
  16th Symposium on Chemistry of Nucleic Acid Components
- Place of Presentation
  Cesky Krumlov, Czech Republic
- Year and Date
  2014-06-08 – 2014-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] Crystal structure of unusual RNA duplex containing strontium ion binding motif
- Author(s)
  Hiroki Kanazawa, Jiro Kondo
- Organizer
  IUCr2014 (23rd Congress and General Assembly of International Union of Crystallography
- Place of Presentation
  Montreal, Canada
- Year and Date
  2014-08-05 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] Crystal structures of the bacterial ribosomal A site containing an antibiotic-resistant mutation
- Author(s)
  Fumika Baba, Mai Koganei, Jiro Kondo
- Organizer
  ISNAC2014 (The 41th International Symposium on Nucleic Acid Chemistry)
- Place of Presentation
  北九州国際会議場（北九州市）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] フッ素を導入した新規アミノグリコシドと細菌リボソームRNAの複合体のＸ線結晶解析
- Author(s)
  金澤宏樹、Juan Pablo Maianti、Stephen Hanessian、近藤次郎
- Organizer
  第3回物構研サイエンスフェスタ
- Place of Presentation
  つくば国際会議場（つくば市）
- Year and Date
  2015-03-17 – 2015-03-18
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] フッ素を導入した新規アミノグリコシドとリボソームRNAの複合体のＸ線結晶解析
- Author(s)
  金澤宏樹、Juan Pablo Maianti、Stephen Hanessian、近藤次郎
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウィンクあいち（名古屋市）
- Year and Date
  2014-07-23 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] Multinuclear NMR spectroscopic studies of metal-ion-mediated DNA base pairs
- Author(s)
  Takenori Dairaku, Itaru Okamoto, Kyoko Furuita, Shuji Oda, Daichi Yamanaka, Yoshinori Kondo, Akira Ono, Chojiri Kijima, Valdimier Sychovsky, Yoshiyuki Tanaka
- Organizer
  The 41th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Kitakyushu International Conference Center
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] Structural and crystal polymorphisms of the mitochondrial ribosomal A-site RNA
- Author(s)
  Mai Miyazaki, Tamaki Tetsumoto, Yukiko Takahashi, Jiro Kondo
- Organizer
  ISNAC2014 (The 41th International Symposium on Nucleic Acid Chemistry)
- Place of Presentation
  北九州国際会議場（北九州市）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-26860025
[Presentation] yntheses of DNA duplexes containing metal ion mediated base pairs
- Author(s)
  Akira Ono, Itaru Okamoto, Hidehito Urata, Hidetake Torigoe, Hisao Saneyoshi, Jiro Kondo, Yoshiyuki Tanaka
- Organizer
  12th European Biological Inorganic Chemistry Conference
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2014-08-24 – 2014-08-28
- Invited
- Data Source
  KAKENHI-PROJECT-24245037
[Presentation] フッ素を導入した新規アミノグリコシドの細菌リボソームRNAへの結合様式の解明
- Author(s)
  金澤宏樹、Juan Pablo Maianti、Stephen Hanessian、近藤次郎
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学（東京都）
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-26860025

1. Ono Akira (10183253)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. TANAKA Yoshiyuki (70333797)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
3. TORIGOE Hidetake (80227678)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. SANEYOSHI Hisao (10564784)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
5. 山田亮 (20343741)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. HANESSIAN Stephen

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
7. BAASOV Timor

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. URATA Hidehito (80211085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. MINAKAWA Noriaki (40209820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岡本到 (40460133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. 藤原章司 (60737196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大樂武範 (80642636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. Ennifar Eric

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Auffinger Pascal

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kondo Jiro 近藤 次郎

KONDO Jiro 近藤 次郎

Research Projects

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Development of novel nucleic acid therapeutics by structural biomimeticsPrincipal Investigator

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Nucleic Acid-Metal Complexes: Preparation, structure analysis, characterization of metal-DNA wires and metal nanocluster-DNA complexes.

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Structural study of the influenza virus genome RNA and development of anti-flu medicinesPrincipal Investigator

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Synthesis and characterization of metallo-DNA nanowire with infinite, uninterrupted one-dimensional metal ions array

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Elucidation of pharmacological effects of antibiotics against genetic diseases caused by nonsense mutations and development of new therapeutic agentsPrincipal Investigator

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Development of DNA based heavy metal ions removing membranes and nanowires-structures, properties, applications.

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Structural studies on antibiotic-resistance mechanisms and their application to drug designPrincipal Investigator

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[Book] Claude Sauter & Benoît Masquida. RNA crystallization. In Roland K. Hartmann, Albrecht Bindereif, Astrid Schon & Eric Westhof (eds.), Handbook of RNA Biochemistry, second edition2014

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[Book] structural decoding of inhibitors targeting the ribosomal decoding A site. In Claudio O. Gualerzi, Letizia Brandi, Attilio Fabbretti & Cynthia L. Pon (eds.), Antibiotics : Targets, Mechanisms and Resistance2013

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[Journal Article] A Novel AgI -DNA Rod Comprising a One-Dimensional Array of 11 Silver Ions within a Double Helical Structure2022

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[Journal Article] Effect of cytosine-Ag+-cytosine base pairing on the redox potential of the Ag+/Ag couple and the chemical reduction of Ag+ to Ag by tetrathiafulvalene2021

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[Journal Article] Crystal structure of a DNA duplex cross-linked by 6-thioguanine-6-thioguanine disulfides: reversible formation and cleavage catalyzed by Cu(II) ions and glutathione2019

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[Journal Article] Novel DNA helical wire containing Hg(II) mediated T:T and T:G pairs2019

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[Journal Article] Conformational adaptation of UNCG loops upon crowding2019

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Kondo Jiro 近藤次郎

KONDO Jiro 近藤次郎