Unekawa Miyuki 畝川美悠紀

… Alternative Names

UNEKAWA Miyuki 畝川美悠紀

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Researcher Number	10548481
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 慶應義塾大学, 医学部(信濃町), 研究員 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 特任講師 2015: 慶應義塾大学, 医学部, 特任講師 2014 – 2015: 慶應義塾大学, 医学部, 助教 2013 – 2015: 慶應義塾大学, 医学部, 特任助教 2012: 慶應義塾大学, 医学部, その他 2011: 慶應義塾大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related / Basic / Social brain science Except Principal Investigator Neurology / Basic Section 52020:Neurology-related / Basic Section 46030:Function of nervous system-related / Pain science
Keywords	Principal Investigator 脳微小循環 / 脱髄 / 髄鞘 / オリゴデンドロサイト前駆細胞 / NG2グリア / オリゴデンドロサイト / 脳虚血 / Neurovascular unit / neurovasucular unit / グリア細胞 … More / 赤血球速度 / アストログリア / Na-K-pump / 脳梗塞 / 大脳皮質性拡延性抑制 / neurovascular unit / ニューロン / アストロサイト / 光遺伝学 … More Except Principal Investigator 脳虚血 / Neurovascular unit / 脳血管障害 / 血管内皮細胞 / neurovascular unit / 脳卒中 / 脳出血 / 二光子顕微鏡 / β１インテグリン / タイトジャンクション / 血管透過性 / 血管内皮 / 凝固因子 / トロンビン / 脳小血管病 / 遺伝性脳小血管病 / 血液脳関門 / 血管内皮障害 / 虚血性神経障害 / 神経科学 / オプトジェネティクス / 脳微小塞栓 / ペリサイト / アストロサイト / 脳微小循環 / 光遺伝学 / 動脈原性塞栓症 / 脳塞栓症 / watershed infarction / microsphere / perfusion pressure / 分水嶺梗塞 / 境界領域梗塞 / マイクロスフェア / 灌流圧 / 心原性脳塞栓症 / dimethyl fumarate / Nrf2 / cerebral ischemia / dimethylfumarate / DMF / Moxibustion / 頭痛 / PID / 大脳皮質拡延性抑制 / 鍼灸の科学化 / Acupuncture / 疼痛制御 / 三叉神経 / 大脳皮質皮質拡延性抑制 / 統合医療 / acupuncture / 鍼灸 / ｔrigger point / 片頭痛 / CSD / 脳循環代謝 / 治療 / 周皮細胞 / 血管再生 / 移植医療 / 再生医療 / 主幹動脈閉塞症 / 脳血管内皮細胞 / 人工血管シート / 治療的血管新生 / 内皮細胞 / 血管新生 / 脳虚血治療 / 人工血管 Less

Evaluation of the regulation mechanism of NG2 glia and remyelination under impaired conditions of the central nervous systemPrincipal Investigator
- Principal Investigator
  
  Unekawa Miyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Keio University
脳血管内皮透過性制御機構の解明による新規神経疾患治療法の確立
- Principal Investigator
  
  伊澤良兼
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Keio University
Mechanisms of microvascular flow regulation in neurovascular coupling and responsiveness to ischemia by using optogenetics
- Principal Investigator
  
  Tomita Yutaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Keio University
A role of astrocyte in neuro-glio-vascular unit concerning cerebral microcirculationPrincipal Investigator
- Principal Investigator
  
  Unekawa Miyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Keio University
The new therapy for cerebral infarction by modulating Keap1/Neaf2 system
- Principal Investigator
  
  Abe Takato
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Osaka City University
  Keio University
Utility of direct oral anticoagulant in the treatment of acute phase cerebral embolism
- Principal Investigator
  
  Itoh Yoshiaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Osaka City University
Mechanism analysis of the trigeminal nervous system modification on cortical spreading depression.
- Principal Investigator
  
  TORIUMI Haruki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Keio University
Tissue engineered blood vessel sheet to prevent cerebral infarction
- Principal Investigator
  
  ITOH Yoshiaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Striatal blood flow changes by middle cerebral artery occlusion and its effect on neurological deficits in mice.2024
- Author(s)
  Unekawa M., Tsukada N., Takizawa T., Tomita Y., Nakahara J., Izawa Y.
- Journal Title
  
  Microcirculation
  
  Volume: － Issue: 6
- DOI
  10.1111/micc.12861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443
[Journal Article] Acceleration of the Development of Microcirculation Embolism in the Brain due to Capillary Narrowing2023
- Author(s)
  Murata Juri、Unekawa Miyuki、Kudo Yuya、Kotani Maho、Kanno Iwao、Izawa Yoshikane、Tomita Yutaka、Tanaka Kenji F.、Nakahara Jin、Masamoto Kazuto
- Journal Title
  
  Stroke
  
  Volume: 54 Issue: 8 Pages: 2135-2144
- DOI
  10.1161/strokeaha.122.042416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07443, KAKENHI-PROJECT-22K07317, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443, KAKENHI-PLANNED-20H05896
[Journal Article] Effect of Goreisan, a Japanese Traditional Medicine, on Cortical Spreading Depolarization in Mice.2022
- Author(s)
  Iba C, Unekawa M, Izawa Y, Nakahara J, Takizawa T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 22 Pages: 13803-13803
- DOI
  10.3390/ijms232213803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06443
[Journal Article] Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter.2022
- Author(s)
  Oishi M, Stefan P, Yamazaki Y, Unekawa M, Adachi R, Yamada M, Imayoshi I, Abe Y, Steinhauser C, Tanaka KF
- Journal Title
  
  Glia
  
  Volume: 71 Issue: 2 Pages: 317-333
- DOI
  10.1002/glia.24273
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-22K06467, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-23K05792
[Journal Article] Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice.2022
- Author(s)
  Unekawa M, Tomita Y, Masamoto K, Kanno I, Nakahara J, Izawa Y
- Journal Title
  
  Brain Res
  
  Volume: 1792 Pages: 148023-148023
- DOI
  10.1016/j.brainres.2022.148023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-21K07443
[Journal Article] Sustained Effects of CGRP Blockade on Cortical Spreading Depolarization-Induced Alterations in Facial Heat Pain Threshold, Light Aversiveness, and Locomotive Activity in the Light Environment.2022
- Author(s)
  Kitagawa S, Tang C, Unekawa M, Kayama Y, Nakahara J, Shibata M
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 22 Pages: 13807-13807
- DOI
  10.3390/ijms232213807
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-19K07849
[Journal Article] Optical manipulation of local cerebral blood flow in the deep brain of freely moving mice2021
- Author(s)
  Abe Yoshifumi、Kwon Soojin、Oishi Mitsuhiro、Unekawa Miyuki、Takata Norio、Seki Fumiko、Koyama Ryuta、Abe Manabu、Sakimura Kenji、Masamoto Kazuto、Tomita Yutaka、Okano Hideyuki、Mushiake Hajime、Tanaka Kenji F.
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 4 Pages: 109427-109427
- DOI
  10.1016/j.celrep.2021.109427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06944, KAKENHI-PROJECT-19K16298, KAKENHI-PUBLICLY-21H00212, KAKENHI-PROJECT-19H03337, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-19K16031, KAKENHI-PLANNED-20H05896
[Journal Article] Protracted hypomobility in the absence of trigeminal sensitization after cortical spreading depolarization: Relevance to migraine postdrome2021
- Author(s)
  Shibata Mamoru、Kitagawa Satoshi、Tang Chunghua、Unekawa Miyuki、Kayama Yohei、Shimizu Toshihiko、Nakahara Jin、Suzuki Norihiro
- Journal Title
  
  Neuroscience Research
  
  Volume: 172 Pages: 80-86
- DOI
  10.1016/j.neures.2021.03.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07849, KAKENHI-PROJECT-21K06443
[Journal Article] Time Series Tracking of Cerebral Microvascular Adaptation to Hypoxia and Hyperoxia Imaged with Repeated In Vivo Two-Photon Microscopy.2021
- Author(s)
  Sugashi T., Niizawa T., Suzuki H., Takuwa H., Unekawa M., Tomita Y., Kanno I., Masamoto K.
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1269 Pages: 323-327
- DOI
  10.1007/978-3-030-48238-1_51
- ISBN
  9783030482367, 9783030482381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443
[Journal Article] Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons2021
- Author(s)
  Hatakeyama N., Unekawa M., Tomita Y. Suzuki N. Nakahara J. Takuwa H., Kanno I., Matsui K., Tanaka K.F., Masamoto K.
- Journal Title
  
  J Cereb Blood Flo Metab
  
  Volume: - Issue: 10 Pages: 2676-2689
- DOI
  10.1177/0271678x211010355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-19K07795, KAKENHI-PUBLICLY-20H05046, KAKENHI-PROJECT-19H03338, KAKENHI-PROJECT-21K06443, KAKENHI-PLANNED-20H05896, KAKENHI-PROJECT-23K21399
[Journal Article] Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 22020
- Author(s)
  Tang Chunhua、Unekawa Miyuki、Shibata Mamoru、Tomita Yutaka、Izawa Yoshikane、Sugimoto Hiroki、Ikeda Keiko、Kawakami Kiyoshi、Suzuki Norihiro、Nakahara Jin
- Journal Title
  
  Cephalalgia
  
  Volume: 40 Issue: 11 Pages: 1177-1190
- DOI
  10.1177/0333102420929028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07849, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-19K17018
[Journal Article] Enhanced susceptibility to cortical spreading depression in two types of Na+, K+-ATPase α2 subunit-deficient mice as a model of familial hemiplegic migraine 2.2018
- Author(s)
  Unekawa, M. Ikeda, K., Tomita, Y., Kawakami, K. and Suzuki, N.
- Journal Title
  
  Cephalalgia
  
  Volume: 38 Issue: 9 Pages: 1515-1524
- DOI
  10.1177/0333102417738249
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08629, KAKENHI-PROJECT-15K06760, KAKENHI-PROJECT-26350981
[Journal Article] Tomita-Seylaz法による慢性頭窓作製後のマウス大脳皮質ミクログリアの長期反復in vivoリアルタイム解析2017
- Author(s)
  結城浩弥, 正本和人, 畝川美悠紀, 冨田裕, 菅野巖, 鈴木則宏
- Journal Title
  
  脳循環代謝
  
  Volume: 28 Pages: 249-256
- NAID
  130006008228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350981
[Journal Article] Dynamic diameter response of intraparenchymal penetrating arteries during cortical spreading depression and elimination of vasoreactivity to hypercapnia in anesthetized mice.2017
- Author(s)
  Unekawa M, Tomita Y, Masamoto K, Toriumi H, Osada T, Kanno I, Suzuki N
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 37 Issue: 2 Pages: 657-670
- DOI
  10.1177/0271678x16636396
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06760, KAKENHI-PROJECT-26350981
[Journal Article] High-mobility group box 1 is an important mediator of microglial activation induced by cortical spreading depression.2017
- Author(s)
  Takizawa T., Shibata M., Kayama Y., Shimizu T., Toriumi H., Ebine T., Unekawa M., Koh A., Yoshimura A., Suzuki N.
- Journal Title
  
  J. Cereb. Blood Flow Metab.
  
  Volume: 37 Issue: 3 Pages: 890-901
- DOI
  10.1177/0271678x16647398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350981, KAKENHI-PROJECT-26460706
[Journal Article] Dynamic flow velocity mapping from fluorescent dye transit times in the brain surface microcirculation of anesthetized rats and mice.2016
- Author(s)
  Hoshikawa R, Kawaguchi H, Takuwa H, Ikoma Y, Tomita Y, Unekawa M, Suzuki N, Kanno I, Masamoto K.
- Journal Title
  
  Microcirculation
  
  Volume: 26 Issue: 6 Pages: 416-425
- DOI
  10.1111/micc.12285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861028, KAKENHI-PROJECT-15K06760, KAKENHI-PROJECT-26350981
[Journal Article] Alterations in the threshold of the potassium concentration to evokecortical spreading depression during the natural estrous cycle in mice2016
- Author(s)
  Taeko Ebine, Haruki Toriumi, Toshihiko Shimizu, Miyuki Unekawa, Tsubasa Takizawa, Yohei Kayama, Mamoru Shibata, Norihiro Suzuki
- Journal Title
  
  Neuroscience Research
  
  Volume: 112 Pages: 57-62
- DOI
  10.1016/j.neures.2016.06.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08996, KAKENHI-PROJECT-26350981
[Journal Article] Hyperperfusion counteracted by transient rapid vasoconstriction followed by long-lasting oligemia induced by cortical spreading depression in anesthetized mice.2015
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Osada T, Masamoto K, Kawaguchi H, Itoh Y, Kanno I, Suzuki N.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 35 Issue: 4 Pages: 689-698
- DOI
  10.1038/jcbfm.2014.250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-15K06760, KAKENHI-PROJECT-26350981, KAKENHI-PROJECT-26461318
[Journal Article] Unveiling astrocytic control of cerebral blood flow with optogenetics2015
- Author(s)
  Masamoto K, Unekawa M, Watanabe T, Toriumi H, Takuwa H, Kawaguchi H, Kanno I, Matsui K, Tanaka K F, Tomita Y, Suzuki N
- Journal Title
  
  Scientific reports
  
  Volume: 5 Issue: 1 Pages: 11455-11455
- DOI
  10.1038/srep11455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06760, KAKENHI-PROJECT-26350981, KAKENHI-PROJECT-15K12765, KAKENHI-PLANNED-25117005, KAKENHI-PUBLICLY-26117501, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-25702054
[Journal Article] アストロサイトによる脳血流調節2015
- Author(s)
  正本和人, 畝川美悠紀, 冨田裕, 菅野巌, 鈴木則宏
- Journal Title
  
  分子精神医学
  
  Volume: 16 Pages: 17-24
- Data Source
  KAKENHI-PROJECT-26350981
[Journal Article] In vivo imaging of the mouse neurovascular unit under chronic cerebral hypoperfusion.2014
- Author(s)
  Yata K, Nishimura Y, Unekawa M, Tomita Y, Suzuki N, Tanaka T, Mizoguchi A, Tomimoto H.
- Journal Title
  
  Stroke.
  
  Volume: 45 Issue: 12 Pages: 3698-3703
- DOI
  10.1161/strokeaha.114.005891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-24510069, KAKENHI-PROJECT-25670127, KAKENHI-PROJECT-26350981
[Journal Article] Cellular origin and regulation of D- and L-serine in vitro and in vivo models of cerebral ischemia.2014
- Author(s)
  Abe T, Suzuki M, Sasabe J, Takahashi S, Unekawa M, Mashima K, Iizumi T, Hamase K, Konno R, Aiso S, Suzuki N.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 34(12) Issue: 12 Pages: 1928-1935
- DOI
  10.1038/jcbfm.2014.164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591276, KAKENHI-PROJECT-26350981, KAKENHI-PROJECT-26461279
[Journal Article] 34. Microvascular sprouting, extension, and creation of new capillary connection with adaptation of the neighboring astrocytes in adult mouse cortex under chronic hypoxia2014
- Author(s)
  Masamoto K, Takuwa H, Seki C, Taniguchi J, Itoh Y, Tomita Y, Toriumi H, Unekawa M, Kawaguchi H, Ito H, Suzuki N, Kanno I
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 34 Issue: 2 Pages: 325-31
- DOI
  10.1038/jcbfm.2013.201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591281, KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-24590732, KAKENHI-PROJECT-25750400, KAKENHI-PROJECT-26350981
[Journal Article] Impairment of CO2 reactivity in RBC velocity and CBF after cortical spreading depression in anesthetized mice2014
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Osada T, Masamoto K, Kawaguchi H, Itoh Y, Kanno I, Suzuki N
- Journal Title
  
  Microvasc. Rev. Commun
  
  Volume: 7
- NAID
  130004678489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26350981
[Journal Article] TRPV1受容体を介した三叉神経の侵害刺激がCSD発生に及ぼす影響2013
- Author(s)
  鳥海春樹, 畝川美悠紀, 黒井俊哉, 柴田護, 清水利彦, 鈴木則宏.
- Journal Title
  
  日本頭痛学会誌
  
  Volume: 39 Pages: 303-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590732
[Journal Article] “Potassium-induced cortical spreading depression bilaterally suppresses the electroencephalogram but only ipsilaterally affects red blood cell velocity in intraparenchymal capillaries.”2013
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Masamoto K, Kanno I, Suzuki N.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 91 Issue: 4 Pages: 578-584
- DOI
  10.1002/jnr.23184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-24590732
[Journal Article] Sustained decrease and remarkable increase in red blood cell velocity in intraparenchymal capillaries associated with potassium-induced cortical spreading depression2012
- Author(s)
  Unekawa M, Tomita M, Tomita Y, Toriumi H, Suzuki N
- Journal Title
  
  Microcirculation
  
  Volume: 19 Issue: 2 Pages: 166-74
- DOI
  10.1111/j.1549-8719.2011.00143.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390182, KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-24590732
[Journal Article] 虚血組織に対する治療的血管新生2012
- Author(s)
  伊藤義彰、黒井俊哉、鳥海春樹、海老根妙子、畝川美悠紀、山田哲、此枝史恵、鈴木則宏
- Journal Title
  
  脳循環代謝
  
  Volume: 23 Pages: 90-94
- Data Source
  KAKENHI-PROJECT-23591281
[Journal Article] Suppressive effect of chronic peroral topiramate on potassium-induced cortical spreading depression in rats2012
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Suzuki N
- Journal Title
  
  Cephalalgia
  
  Volume: 32 Issue: 7 Pages: 518-527
- DOI
  10.1177/0333102412444015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500422, KAKENHI-PROJECT-24590732
[Journal Article] Repeated longitudinal in vivo imaging of neuro-glio-vascular unit at the peripheral boundary of ischemia inmouse cerebral cortex2012
- Author(s)
  Masamoto K, TomitaY, Toriumi H, Aoki I, Unekawa M, Takuwa H, Itoh Y, Suzuki N, Kanno I
- Journal Title
  
  Neuroscience
  
  Volume: (未)(Epub ahead of print) Pages: 190-200
- DOI
  10.1016/j.neuroscience.2012.03.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390249, KAKENHI-PROJECT-23591281, KAKENHI-PROJECT-24500422
[Presentation] Development of the pericytes-specific optogenic tool.2023
- Author(s)
  Iba C, Abe Y, Unekawa M, Tomita Y, Tanaka KF
- Organizer
  US-Japan Joint Workshop on the Neurovascular Unit 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex by transient occlusion of middle cerebral artery in mice.2023
- Author(s)
  Unekawa M, Takizawa T, Tomita Y, Nakahara J, Izawa Y
- Organizer
  第48回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Quantitative characterization of the microglial response to chronic hypoxia in the mouse cortex.2023
- Author(s)
  Kudo Y., Sugashi T., Yuki H., Soga N., Unekawa M., Tomita Y., Izawa Y., Nakahara J., Kanno I., Masamoto K.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] ミクログリアの個性を示す画像化手法の提案：生体二光子顕微鏡による検討2023
- Author(s)
  工藤雄也, 須貸琢磨, 結城浩弥, 曽我直人, 畝川美悠紀, 冨田裕, 伊澤良兼, 中原仁, 菅野巖, 正本和人
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流変化と虚血・梗塞巣の形成2023
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第48回日本脳卒中会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流変化と虚血・梗塞巣の形成2023
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第48回日本脳卒中会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex by transient occlusion of middle cerebral artery in mice2023
- Author(s)
  Unekawa M, Takizawa T, Tomita Y, Nakahara J, Izawa Y
- Organizer
  第48回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流変化と虚血・梗塞巣の形成2023
- Author(s)
  畝川美悠紀
- Organizer
  日本脳卒中学会
- Data Source
  KAKENHI-PROJECT-21K07443
[Presentation] Capillary constriction enhances microcirculation embolism in the mouse cortex.2023
- Author(s)
  Kudo Y, Murata J, Unekawa M, Kanno I, Izawa Y, Tomita Y, Tanaka KF, Nakahara J, Masamoto K
- Organizer
  US-Japan Joint Workshop on the Neurovascular Unit 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Development of the pericytes-specific optogenic tool.2023
- Author(s)
  Iba C, Abe Y, Unekawa M, Tomita Y, Tanaka KF
- Organizer
  US-Japan Joint Workshop on the Neurovascular Unit 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex in stroke model mice.2023
- Author(s)
  Unekawa M., Tsukada N., Takizawa T., Tomita Y., Nakahara J., Izawa Y.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] ミクログリアの個性を示す画像化手法の提案：生体二光子顕微鏡による検討2023
- Author(s)
  工藤雄也, 須貸琢磨, 結城浩弥, 曽我直人, 畝川美悠紀, 冨田裕, 伊澤良兼, 中原仁, 菅野巖, 正本和人.
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Capillary constriction enhances microcirculation embolism in the mouse cortex.2023
- Author(s)
  Kudo Y, Murata J, Unekawa M, Kanno I, Izawa Y, Tomita Y, Tanaka KF, Nakahara J, Masamoto K
- Organizer
  US-Japan Joint Workshop on the Neurovascular Unit 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Quantitative characterization of the microglial response to chronic hypoxia in the mouse cortex.2023
- Author(s)
  Kudo Y., Sugashi T., Yuki H., Soga N., Unekawa M., Tomita Y., Izawa Y., Nakahara J., Kanno I., Masamoto K.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex in stroke model mice.2023
- Author(s)
  Unekawa M., Tsukada N., Takizawa T., Tomita Y., Nakahara J., Izawa Y.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Establishment of pericytes-specific optogenetic animal.2023
- Author(s)
  Iba C, Unekawa M, Tanaka KF
- Organizer
  第48回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Effects of goreisan, an herbal medicine, on cortical spreading depolarization.2022
- Author(s)
  Iba C, Unekawa M, Izawa Y, Nakahara J, Takizawa T
- Organizer
  64th Annual Scientific Meeting of the American Headache Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流動態と梗塞形成2022
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 脳微小血管の収縮による微小塞栓の形成2022
- Author(s)
  工藤雄也, 村田樹里, 小谷真穂, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Increased miroembolism caused by capillary constriction in the brain.2022
- Author(s)
  Kotani M, Murata J, Unekawa M, Kanno I, Tomita Y, Tanaka KF, Nakahara J, Masamoto K
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Increased miroembolism caused by capillary constriction in the brain.2022
- Author(s)
  Kotani M, Murata J, Unekawa M, Kanno I, Tomita Y, Tanaka KF, Nakahara J, Masamoto K
- Organizer
  9th World Congress of Biomechanics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流動態変化と梗塞形成2022
- Author(s)
  畝川美悠紀
- Organizer
  日本脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-21K07443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流動態と梗塞形成2022
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 脳微小血管の収縮による微小塞栓の形成2022
- Author(s)
  工藤雄也, 村田樹里, 小谷真穂, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] タバコと片頭痛の関係についての臨床および基礎的検討2021
- Author(s)
  滝沢翼, 畝川美悠紀, 渡邊成美, 加川志津子, 伊庭知里, 中山真吾, 中鉢正太郎, 宮崎直己, 竹村亮, 石井亮太, 柴田護, 福永興壱, 中原仁
- Organizer
  第39回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] マウス大脳皮質におけるミクログリアの長期観察と低酸素暴露への適応2021
- Author(s)
  須貸拓馬, 結城浩弥, 畝川美悠紀, 冨田裕, 菅野巖, 中原仁, 正本和人
- Organizer
  第25回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] オプトジェネティクスを用いた脳微小血管の操作2021
- Author(s)
  小谷真穂, 村田樹里, 大石光洋, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第25回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] オプトジェネティクスを用いた脳微小血管の操作2021
- Author(s)
  小谷真穂, 村田樹里, 大石光洋, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第25回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Vasoconstriction and hypoperfusion induced by photoactivation of the ChR2-expressing vascular cells.2021
- Author(s)
  冨田裕, 村田樹里, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巌, 田中謙二, 正本和人, 中原仁
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Manipulation of cerebral microcirculation flow via photo-stimulation to vascular mural cells with optogenetics.2021
- Author(s)
  Murata J., Oishi M., Unekawa M., Kanno I., Tomita Y., Tanaka K., Nakahara J., Masamoto K.
- Organizer
  第46回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 光を用いた脳微小循環動態のイメージングと操作2021
- Author(s)
  正本和人, 村田樹里, 畝川美悠紀, 冨田裕, 菅野巖.
- Organizer
  第37回スパズム・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 喫煙が皮質拡延性脱分極に及ぼす影響について2021
- Author(s)
  滝沢翼, 畝川美悠紀, 伊庭知里, 加川志津子, 渡邊成美, 中山真吾, 桜井香, 宮崎直己, 石田典之, 竹村亮, 柴田護, 伊澤良兼, 中鉢正太郎, 福永興壱, 中原仁
- Organizer
  第64回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] マウス大脳皮質におけるミクログリアの長期観察と低酸素暴露への適応2021
- Author(s)
  須貸拓馬, 結城浩弥, 畝川美悠紀, 冨田裕, 菅野巖, 中原仁, 正本和人
- Organizer
  第25回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Imaging of Cerebral Microcirculation and Expectations for Biomedical Engineering2021
- Author(s)
  Tomita Y., Unekawa M., Izawa Y., Masamoto K., Kanno I., Nakahara J.
- Organizer
  第46回日本微小循環学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Imaging of water kinetics during cytotoxic edema using indirect MRI with O17-labeled water.2021
- Author(s)
  Ishikawa T., Hoshino Y., Kameda H., Komaki Y., Unekawa M., Tomita Y., Nakahara J., Kudo K., Yasui M.
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Vasoconstriction and hypoperfusion induced by photoactivation of the ChR2-expressing vascular cells.2021
- Author(s)
  冨田裕, 村田樹里, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巌, 田中謙二, 正本和人, 中原仁
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Analysis of red blood cell velocity in intraparenchymal capillaries and arterial diameter in mice.2020
- Author(s)
  冨田裕, 畝川美悠紀, 伊澤良兼, 正本和人, 菅野巌, 中原仁.
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] アクアポリン４は水中毒によるparavascular spaceの閉塞と脳神経活動の低下を促進する2020
- Author(s)
  石川智愛, 畝川美悠紀, 冨田裕, 中原仁, 安井正人.
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Dynamic response of arterial diameter and red blood cell velocity in capillaries associated with cortical spreading depolarization/depression2020
- Author(s)
  Tang C., Unekawa M., Tomita Y., Masamoto K., Kanno I., Nakahara J.
- Organizer
  第45回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Optogenetic manipulation of cerebral microcirculation by transcranial photostimulation to the channelrhodopsin-2 expressing mouse brains.2020
- Author(s)
  Murata J., Unekawa M., Kanno I., Tomita Y., Tanaka K., Nakahara J., Masamoto K.
- Organizer
  第45回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 大脳皮質拡延性抑制／脱分極が結ぶ片頭痛と脳卒中2018
- Author(s)
  畝川美悠紀, 冨田裕, 鈴木則宏.
- Organizer
  第43回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Enhanced susceptibility to cortical spreading depression and different degree in two-types of Na+,K+-ATPase a2 subunit-deficient mice as a model of familial hemiplegic migraine 2.2017
- Author(s)
  Unekawa M., Ikeda K., Tomita Y., Kawakami K., Suzuki N.
- Organizer
  18th Congress of the International Headache Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Effect of spreading depolarization on cerebral blood flow and development of infarction under experimental ischemia in anesthetized mice.2017
- Author(s)
  Unekawa M., Tomita Y., Toriumi H., Osada T., Masamoto K., Kanno I., Suzuki N.
- Organizer
  28th International Symposium on Cerebral Blood Flow, Metabolism & Function
- Place of Presentation
  ベルリン(ドイツ)
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 低酸素誘発性脳微小血管リモデリングにおけるミクログリアの関与2017
- Author(s)
  曽我直人, 結城浩弥, 須貸拓馬, 畝川美悠紀, 冨田裕, 菅野巖, 鈴木則宏, 正本和人
- Organizer
  酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 中大脳動脈閉塞時に発生する拡延性脱分極が脳血流と梗塞形成に及ぼす影響2017
- Author(s)
  畝川美悠紀, 冨田裕, 鳥海春樹, 長田高志, 正本和人, 菅野巖, 鈴木則宏.
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪国際会議場(大阪市北区)
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Neuroprotective effects of dimethyl fumarate on cerebral ischemia-reperfusion injury in mice2017
- Author(s)
  Minami K., Abe T., Tsukada N., Unekawa M., Takahashi S., Suzuki N.
- Organizer
  The 8th Korea-Japan Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Spatiotemporal changes in cerebral blood flow induced by transcranial photostimulation to cortical neurons or astrocytes in the transgenic mice expressing channelrhodopsin-2.2017
- Author(s)
  Hatakeyama N., Masamoto K., Unekawa M., Takuwa H., Kanno I., Matsui K., Tanaka K. F., Tomita Y., Suzuki N.
- Organizer
  28th International Symposium on Cerebral Blood Flow, Metabolism & Function
- Place of Presentation
  ベルリン(ドイツ)
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 神経賦活とグリア賦活による脳血流反応の比較：オプトジェネティクスによる検討2017
- Author(s)
  畠山菜緒, 正本和人, 畝川美悠紀, 田桑弘之, 菅野巖, 松井広, 田中謙二, 冨田裕, 鈴木則宏.
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪国際会議場(大阪市北区)
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Widespread c-Fos expression after cortical spreading depression; possible differences between two types of animal models of familial hemiplegic migraine 22017
- Author(s)
  Unekawa M., Ikeda K., Tomita Y., Kawakami K., Suzuki N.
- Organizer
  The XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 脳虚血後のグリア細胞の形状変化におけるin vivo長期解析2017
- Author(s)
  渡部真子, 須貸拓馬, 蜂谷亮太, 安部貴人, 畝川美悠紀, 鳥海春樹, 冨田裕, 鈴木則宏, 田桑弘之, 菅野巖, 正本和人
- Organizer
  日本機械学会第30 回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Hemodynamic response to optogenetic activation of ChR2-expressing neurons or astrocytes in the mouse cortex2017
- Author(s)
  Hatakeyama N., Masamoto K., Unekawa M., Takuwa H., Kanno I., Matsui K., Tanaka K. F., Tomita Y., Suzuki N.
- Organizer
  第9回光操作研究会
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Cerebral blood flow responses to photostimulation in the transgenic miceexpressing channelrhodopsin-2 in the cortical neurons or astrocytes.2017
- Author(s)
  Hatakeyama N., Masamoto K., Unekawa M., Takuwa H., Kanno I., Matsui K., Tanaka K., Tomita Y., Suzuki N.
- Organizer
  The XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Na+,K+-ATPase α2サブユニット遺伝子欠損マウスにおける皮質拡延性抑制に対する感受性と脳内c-Fos発現分布2017
- Author(s)
  畝川美悠紀, 池田啓子, 冨田裕, 川上潔, 鈴木則宏
- Organizer
  第60回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Repeated longitudinal in vivo imaging of cortical microglia under chronic hypoxia in the mice using twophoton microscopy with a closed cranial window technique.2017
- Author(s)
  Kanno I., Masamoto K., Yuki H., Sugashi T., Unekawa M., Tomita Y., Suzuki N.
- Organizer
  28th International Symposium on Cerebral Blood Flow, Metabolism & Function
- Place of Presentation
  ベルリン(ドイツ)
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Longitudinal two-photon imaging of microvascular remodeling and microglial response to chronic hypoxia in in vivo mouse cortex.2017
- Author(s)
  Yuki T., Masamoto K., Unekawa M., Sugashi T., Tomita Y., Kanno I., Suzuki N.
- Organizer
  第42回日本微小循環学会総会
- Place of Presentation
  富山国際会議場(富山県富山市)
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 一時的脳虚血時に発生する拡延性脱分極に伴う血流変化と梗塞形成に対する影響2016
- Author(s)
  畝川美悠紀, 冨田裕, 鳥海春樹, 長田高志, 正本和人, 菅野巖, 鈴木則宏
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  あわぎんホール(徳島県徳島市)
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] オプトジェネティクスを用いたアストロサイト・ニューロン賦活による脳血流空間伝播の比較2016
- Author(s)
  畠山菜緒, 正本和人, 畝川美悠紀, 田桑弘之, 菅野巖, 松井広, 田中謙二, 冨田裕, 鈴木則宏
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  あわぎんホール(徳島県徳島市)
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Dynamic flow velocity mapping based on transient time measurements of fluorescent dye.2016
- Author(s)
  Hoshikawa R., Kawaguchi H., Takuwa H., Ikoma Y., Tomita Y., Unekawa M., Suzuki N., Kanno I., Masamoto K.
- Organizer
  第41回日本微小循環学会総会
- Place of Presentation
  コクヨホール(東京都港区)
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Response of cerebral blood flow to optogenetic photostimulation of cortical neurons and astrocytes2016
- Author(s)
  冨田裕, 渡部竜志, 正本和人, 畝川美悠紀, 鳥海春樹, 田桑弘之, 菅野巌, 松井広, 田中謙二, 鈴木則宏.
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場(神戸市中央区)
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Acceleration of red blood cells in intraparenchymal capillaries and dilation of arterial diameter in response to hypercapnia were diminished after passage of cortical spreading depression in anesthetized mice2016
- Author(s)
  Yutaka Tomita, Miyuki Unekawa, Haruki Toriumi, Takashi Osada, Kazuto Masamoto, Hiroshi Kawaguchi, Yoshiaki Itoh, Iwao Kanno, Norihiro Suzuki
- Organizer
  微小循環学会
- Place of Presentation
  コクヨホール(東京都港区)
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-26461318
[Presentation] Tomita-Seylaz法による慢性頭窓作成後のマウス大脳皮質ミクログリアのin vivo長期反復解析.2016
- Author(s)
  結城浩弥, 正本和人, 畝川美悠紀, 冨田裕, 菅野巖, 鈴木則宏.
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  あわぎんホール(徳島県徳島市)
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Acceleration of red blood cells in intraparenchymal capillaries and dilation of arterial diameter in response to hypercapnia were diminished after passage of cortical spreading depression in anesthetized mice.2016
- Author(s)
  Tomita Y., Unekawa M., Toriumi H., Osada T., Masamoto K., Kawaguchi H., Itoh Y., Kanno I., Suzuki N.
- Organizer
  第41回日本微小循環学会総会
- Place of Presentation
  コクヨホール(東京都港区)
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Heterogeneous response of microcirculation to spreading depolarization evoked during middle cerebral artery occlusion in anesthetized mice.2016
- Author(s)
  Unekawa M., Tomita Y., Toriumi H., Osada T., Masamoto K., Kanno I., Suzuki N.
- Organizer
  第41回日本微小循環学会総会
- Place of Presentation
  コクヨホール(東京都港区)
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] マウス脳虚血再灌流モデルにおけるフマル酸ジメチルの神経保護効果2016
- Author(s)
  南和志, 安部貴人, 塚田直己, 畝川美悠紀, 髙橋愼一, 鈴木則宏.
- Organizer
  第41回日本脳卒中学会総会
- Place of Presentation
  札幌市教育文化会館(札幌市中央区)
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] マウス脳虚血再灌流モデルにおけるフマル酸ジメチルの神経保護効果2016
- Author(s)
  南　和志、安部貴人、塚田直己、畝川美悠紀、髙橋愼一、鈴木則宏
- Organizer
  第41回日本脳卒中学会総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26461279
[Presentation] Dynamics of red blood cells in intraparenchymal capillaries and arterial diameter during cortical spreading depression observed with high-speed camera confocal fluorescence microscope in anesthetized mice.2015
- Author(s)
  Tomita Y, Unekawa M, Toriumi H, Osada T, Masamoto K, Kawaguchi H, Itoh Y, Kanno I, Suzuki N.
- Organizer
  10th World Congress for Microcirculation
- Place of Presentation
  Kyoto International Conference Center(京都府京都市)
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 二光子顕微鏡を用いた生体マウス脳内ミクログリアの三次元長期イメージングと定量解析2015
- Author(s)
  結城浩弥, 正本和人, 畝川美悠紀, 冨田裕, 鳥海春樹, 海老根妙子, 菅野巖, 鈴木則宏
- Organizer
  第4回ニューロフォトニクス研究会
- Place of Presentation
  ホテルグランドヒル市ヶ谷(東京都新宿区)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Vasoreactivity of intracortical penetrating arteries of the cerebral cortex in response to cortical spreading depression and hypercapnia in anesthetized mice.2015
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Osada T, Masamoto K, Kanno I, Suzuki N.
- Organizer
  10th World Congress for Microcirculation
- Place of Presentation
  Kyoto International Conference Center(京都府京都市)
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Astrocytic depolarization induced rapid and broad increase in CBFin in vivo mouse cortex.2015
- Author(s)
  Masamoto K, Unekawa M, Watanabe T, Toriumi H, Takuwa H K, H., Kanno I, Matsui K, Tanaka K, Tomita Y, Suzuki N.
- Organizer
  27th International Symposium on Cerebral Blood Flow, Metabolism & Function
- Place of Presentation
  バンクーバー(カナダ)
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Optogenetic activation of astrocyte-blood flow signaling in the anesthetized mouse cortex.2015
- Author(s)
  Tomita Y, Masamoto K, Unekawa M, Watanabe T, Toriumi H, Takuwa H, Kawaguchi H, Kanno I, Matsui K, Tanaka K, Suzuki N.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ (新潟コンベンションセンター)(新潟県新潟市)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 大脳皮質性拡延性抑制が実質内穿通動脈口径と局所脳血流および二酸化炭素負荷に対する反応性に及ぼす影響2015
- Author(s)
  畝川美悠紀, 冨田裕, 鳥海春樹, 長田高志, 正本和人, 菅野巖, 鈴木則宏
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山国際会議場(富山県富山市)
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Temporal diametric change of intracortical penetrating arteries in response to cortical spreading depression observed with two-photon microscopy in anesthetized mice.2015
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Osada T, Masamoto K, Kanno I, Suzuki N.
- Organizer
  27th International Symposium on Cerebral Blood Flow, Metabolism & Function
- Place of Presentation
  バンクーバー(カナダ)
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] オプトジェネティクスを用いた脳賦活による脳血流反応の空間伝播解析2015
- Author(s)
  渡部竜志, 正本和人, 畝川美悠紀, 冨田裕, 田桑弘之, 菅野巖, 松井広, 田中謙二, 鈴木則宏
- Organizer
  第4回ニューロフォトニクス研究会
- Place of Presentation
  ホテルグランドヒル市ヶ谷(東京都新宿区)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Spatiotemporal dynamics of cerebral blood flow during focal activation with optogenetic photostimulation to the cortical neurons and astrocytes.2015
- Author(s)
  Watanabe T, Masamoto K, Unekawa M, Toriumi H, Takuwa H, Kanno I, Matsui K, Tanaka K, Tomita Y, Suzuki N.
- Organizer
  10th World Congress for Microcirculation
- Place of Presentation
  Kyoto International Conference Center(京都府京都市)
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] The behavior of red blood cell in intraparenchymal capillaries during cortical spreading depression observed with high-speed camera confocal fluorescence microscope in anesthetized mice.2015
- Author(s)
  Tomita Y, Unekawa M, Toriumi H, Osada T, Masamoto K, Kawaguchi H, Itoh Y, Kanno I, Suzuki N.
- Organizer
  27th International Symposium on Cerebral Blood Flow, Metabolism & Function
- Place of Presentation
  バンクーバー(カナダ)
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 家族性片麻痺性片頭痛２型モデルマウスにおける皮質拡延性抑制感受性および反応性2015
- Author(s)
  畝川美悠紀, 池田啓子, 冨田裕, 鳥海春樹, 海老根妙子, 川上潔, 鈴木則宏
- Organizer
  第43回日本頭痛学会総会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Irbesartan長期投与による脳虚血再灌流領域の血管への炎症性細胞接着の抑制2013
- Author(s)
  鳥海春樹, 海老根妙子, 萱間洋平, 畝川美悠紀, 山田哲, 冨田裕, 伊藤義彰, 鈴木則宏
- Organizer
  脳卒中学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591281
[Presentation] Repeated 3D imaging of microvascular-astroglia restructuring induced by chronic hypoxia in mouse cerebral cortex2013
- Author(s)
  Kazuto Masamoto, Hiroyuki Takuwa, Takuma Sugashi, Yukio Yamada, Yutaka Tomita, Miyuki Unekawa, Haruki Toriumi, Yoshiaki Itoh, Norihiro Suzuki, Hiroshi Ito, Iwao Kanno
- Organizer
  日本微小循環学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591281
[Presentation] Repeated 3D liv e imaging of microvascular-astroglia restructuring induced by hypoxia in mouse cerebral cortex.2013
- Author(s)
  Masamoto K, Takuwa H, Sugashi T, Yamada Y, Tomita Y, Unekawa M, Toriumi H, Itoh Y, Suzuki N, Ito H, Kanno I.
- Organizer
  第38回日本微小循環学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590732
[Presentation] Propagation of changes in diameter of pial arteries and cerebral blood flow following cortical spreading depression in anesthetized mice2013
- Author(s)
  Miyuki Unekawa, Yutaka Tomita, Haruki Toriumi, Takashi Osada, Kazuto Masamoto, Yoshiaki Itoh, Iwao Kanno, Norihiro Suzuki
- Organizer
  日本微小循環学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591281
[Presentation] Irbetanの長期投与が一過性局所脳血管閉塞領域の血管への細胞接着に及ぼす効果2013
- Author(s)
  鳥海春樹, 海老根妙子, 萱間洋平, 畝川美悠紀, 山田哲, 冨田裕, 伊藤義彰, 鈴木則宏.
- Organizer
  第38回日本脳卒中学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590732
[Presentation] Propagation of changes in diameter of pial a rteries and cerebral blood flow following cortical spreading depression in anesthetized mice.2013
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Osada T, Masamoto K, Itoh Y, Kanno I, Suzuki N.
- Organizer
  第38回日本微小循環学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590732
[Presentation] 脳小血管病におけるNeurovascular Unitの障害2012
- Author(s)
  伊藤義彰、鳥海春樹、畝川美悠紀、海老根妙子、山田哲、此枝史恵、小泉健三、冨田裕、鈴木則宏
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23591281
[Presentation] 麻酔下マウスにおける大脳皮質性拡延性抑制誘発時の脳表動静脈および毛細血管の口径と脳血流の変化2012
- Author(s)
  畝川美悠紀, 冨田裕, 鳥海春樹, 長田高志, 正本和人, 川口拓之, 伊藤義彰, 菅野巖, 鈴木則宏.
- Organizer
  第24回日本脳循環代謝学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24590732
[Presentation] マウス大脳皮質虚血辺縁部におけるNeuro-glio-vascular unitのin vivo形態解析.2012
- Author(s)
  正本和人, 冨田裕, 鳥海春樹, 青木伊知男, 畝川美悠紀, 田桑弘之, 伊藤浩, 伊藤義彰, 鈴木則宏, 菅野巖.
- Organizer
  第24回日本脳循環代謝学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24590732
[Presentation] Mechanism regulating D-serine and L-serine during transient middle cerebral artery occlusion in a mouse model
- Author(s)
  Abe T, Sasabe J, Suzuki M, Takahashi S, Unekawa M, Iizumi T, Aiso S, Suzuki N
- Organizer
  9th World Stroke Congress
- Place of Presentation
  Halic Congress Centre (Istanbul, Turkey)
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] アストロサイト賦活による局所脳血流反応の空間伝播の解析
- Author(s)
  渡部竜志, 正本和人, 畝川美悠紀, 結城浩弥, 新夕雅啓, 鳥海春樹, 田桑弘之, 川口拓之, 菅野巖, 松井広, 田中謙二, 冨田裕, 鈴木則宏
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山コンベンションセンター(岡山市)
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] The behavior of red blood cell in intraparenchymal capillaries during cortical spreading depression observed with high-speed camera confocal fluorescence microscope in anesthetized mice
- Author(s)
  Tomita Y, Unekawa M, Toriumi H, Osada T, Masamoto K, Kawaguchi H, Itoh Y, Kanno I, Suzuki N
- Organizer
  27th International Symposium on Cerebral Blood Flow Metabolism & Function
- Place of Presentation
  Vancouver Convention Centre (Vancouver, Canada)
- Year and Date
  2015-06-27 – 2015-06-30
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] MECHANISM REGULATING D-SERINE AND L-SERINE DURING TRANSIENT MIDDLE CEREBRAL ARTERY OCCLUSION IN A MOUSE MODEL
- Author(s)
  T. Abe, J. Sasabe, M. Suzuki, S. Takahashi, M. Unekawa, T. Iizumi, S. Aiso, N. Suzuki.
- Organizer
  World Stroke Congress 2014
- Place of Presentation
  トルコ・イスタンブール・Halic Congress Centeｒ
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26461279
[Presentation] Optogenetic activation of astrocyte-blood flow signaling in the anesthetized mouse cortex
- Author(s)
  Tomita Y, Masamoto K, Unekawa M, Watanabe T, Toriumi H, Takuwa H, Kawaguchi H, Kanno I, Matsui K, Tanaka K, Suzuki N
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  新潟コンベンションセンター(新潟)
- Year and Date
  2015-05-20 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Changes in diameter of cerebral microvessels and blood flow associated with potassium-induced cortical spreading depression in anesthetized mice
- Author(s)
  Miyuki Unekawa, Yutaka Tomita, Haruki Toriumi, Taeko Ebine, Kazuto Masamoto, Yoshiaki Itoh, Iwao Kanno, Norihiro Suzuki
- Organizer
  日本微小循環学会
- Place of Presentation
  盛岡グランドホテル、岩手県
- Data Source
  KAKENHI-PROJECT-23591281
[Presentation] Astrocytic depolarization induced rapid and broad increase in CBF in in vivo mouse cortex
- Author(s)
  Masamoto K, Unekawa M, Watanabe T, Toriumi H, Takuwa H, Kawaguchi H, Kanno I, Matsui K, Tanaka K, Tomita Y, Suzuki N
- Organizer
  27th International Symposium on Cerebral Blood Flow Metabolism & Function
- Place of Presentation
  Vancouver Convention Centre (Vancouver, Canada)
- Year and Date
  2015-06-27 – 2015-06-30
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] Temporal diametric change of intracortical penetrating arteries in response to cortical spreading depression observed with two-photon microscopy in anesthetized mice
- Author(s)
  Unekawa M, Tomita Y, Toriumi H, Osada T, Masamoto K, Kanno I, Suzuki N
- Organizer
  27th International Symposium on Cerebral Blood Flow Metabolism & Function
- Place of Presentation
  Vancouver Convention Centre (Vancouver, Canada)
- Year and Date
  2015-06-27 – 2015-06-30
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 大脳皮質性拡延性抑制誘発時の脳表軟膜動脈および実質内穿通動脈の口径変化
- Author(s)
  畝川美悠紀, 冨田裕, 鳥海春樹, 長田高志, 正本和人, 菅野巖, 鈴木則宏
- Organizer
  第42回日本頭痛学会総会
- Place of Presentation
  海峡メッセ下関(下関市)
- Year and Date
  2014-11-14 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-26350981
[Presentation] 麻酔下マウスにおける大脳皮質性拡延性抑制誘発時の実質内穿通動脈の口径変化
- Author(s)
  畝川美悠紀, 冨田裕, 鳥海春樹, 長田高志, 正本和人, 菅野巖, 鈴木則宏
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山コンベンションセンター(岡山市)
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26350981

1. Tomita Yutaka (60276251)

# of Collaborated Projects: 3 results

# of Collaborated Products: 85 results
2. 伊澤良兼 (90468471)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
3. ITOH Yoshiaki (90265786)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. Abe Takato (30365233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 滝沢翼 (30778874)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. HOSHINO Haruhiko (50407110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TORIUMI Haruki (30528203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. TANAKA Kenji (30329700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
9. MASAMOTO Kazuto (60455384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 40 results
10. 高橋慎一 (20236285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大木宏一 (10348633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山田哲 (80445296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 塚田直己 (80868563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. EBINE Taeko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. SUZUKI Norihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 51 results
16. KANNO Iwao

# of Collaborated Projects: 1 results

# of Collaborated Products: 39 results
17. WATANABE Tatsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
18. HATAKEYAMA Nao

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. TAKUWA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. TAKAHASHI Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. Ikeda Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 阿部貴人

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
23. 川上潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 高田則雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 柴田護

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
26. 清水利彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Unekawa Miyuki 畝川 美悠紀

UNEKAWA Miyuki 畝川 美悠紀

Research Projects

Research Products

Co-Researchers

Evaluation of the regulation mechanism of NG2 glia and remyelination under impaired conditions of the central nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳血管内皮透過性制御機構の解明による新規神経疾患治療法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of microvascular flow regulation in neurovascular coupling and responsiveness to ischemia by using optogenetics

Principal Investigator

Project Period (FY)

Research Category

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A role of astrocyte in neuro-glio-vascular unit concerning cerebral microcirculationPrincipal Investigator

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The new therapy for cerebral infarction by modulating Keap1/Neaf2 system

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Utility of direct oral anticoagulant in the treatment of acute phase cerebral embolism

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Mechanism analysis of the trigeminal nervous system modification on cortical spreading depression.

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Tissue engineered blood vessel sheet to prevent cerebral infarction

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[Journal Article] Striatal blood flow changes by middle cerebral artery occlusion and its effect on neurological deficits in mice.2024

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[Journal Article] Acceleration of the Development of Microcirculation Embolism in the Brain due to Capillary Narrowing2023

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[Journal Article] Effect of Goreisan, a Japanese Traditional Medicine, on Cortical Spreading Depolarization in Mice.2022

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[Journal Article] Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter.2022

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[Journal Article] Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice.2022

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[Journal Article] Sustained Effects of CGRP Blockade on Cortical Spreading Depolarization-Induced Alterations in Facial Heat Pain Threshold, Light Aversiveness, and Locomotive Activity in the Light Environment.2022

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Unekawa Miyuki 畝川美悠紀

UNEKAWA Miyuki 畝川美悠紀