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Ishikawa Mitsuru  石川 充

… Alternative Names

ISHIKAWA Mitsuru  石川 充

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Researcher Number 10613995
Other IDs
  • ORCIDhttps://orcid.org/0009-0000-9895-7238
Affiliation (Current) 2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 藤田医科大学, 医学部, 講師
2023: 慶應義塾大学, 医学部(信濃町), 訪問講師
2021 – 2023: 慶應義塾大学, 医学部(信濃町), 特任講師
2016 – 2021: 慶應義塾大学, 医学部(信濃町), 特任助教
2014 – 2015: 慶應義塾大学, 医学部, 特任助教
2011: 富山大学, 大学院・医学薬学研究部(薬学), 助教
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 52:General internal medicine and related fields / Pediatrics / Basic Section 51030:Pathophysiologic neuroscience-related / Neurophysiology / General neuroscience / Biological pharmacy
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Biological Sciences
Keywords
Principal Investigator
iPS細胞 / スクリーニング / 抑制性神経細胞 / 神経分化 / 精神疾患 / てんかん / 脳・神経 / 発生・分化 / 脳神経疾患 / 神経科学 … More / 直接誘導 / 末梢血細胞 / 神経疾患 / エピゲノム / iN / ダイレクトリプログラミング / 神経活動 / 不死化リンパ芽球 / Neurogenin2 / 細胞移動 / SRGAP2 / 進化生物学 / 興奮性神経細胞 / 重複遺伝子 / 分節重複 / 霊長類 / 進化 / 神経発達 / オルガノイド / 大脳皮質 / ゲノム編集 / iPS 細胞 / Rho / 樹状突起 / 転写因子 / SRF / アクチン … More
Except Principal Investigator
iPS細胞 / 小児難治てんかん / ゲノム編集 / mTOR / AKT3 / トランスクリプトーム解析 / カルシウム / ミトコンドリアDNA / 視床室傍核 / ミトコンドリア / 統合失調症 / 双極性障害 Less
  • Research Projects

    (9 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (12 People)
  •  発達性てんかん性脳症モデル化のための細胞種特異的iPS神経の機能イメージング構築Principal Investigator

    • Principal Investigator
      石川 充
    • Project Period (FY)
      2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Fujita Health University
  •  発達性てんかん性脳症の個別化医療を促進させる細胞種特異的iPS神経系培養基盤の導出Principal Investigator

    • Principal Investigator
      石川 充
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Fujita Health University
      Keio University
  •  Molecular pathology investigation for targeted therapy of intractable pediatric epilepsy via mTOR pathway hyperactivation

    • Principal Investigator
      森本 昌史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Custom generation of human brain cells: establishment of in vitro differentiation system for whole cell typesPrincipal Investigator

    • Principal Investigator
      石川 充
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Keio University
  •  Neuronal Activity Screening for Psychiatric Disorders Enabled by Subtype-specific Neuronal induction SystemsPrincipal Investigator

    • Principal Investigator
      Ishikawa Mitsuru
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Keio University
  •  Constructive understanding of bipolar disorder and schizophrenia by transomics and modeling

    • Principal Investigator
      Kato Tadafumi
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
      Institute of Physical and Chemical Research
  •  Direct differentiation of peripheral blood cells into neurons for the analysis of epigenetic-related diseasesPrincipal Investigator

    • Principal Investigator
      ISHIKAWA Mitsuru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Keio University
  •  In vitro brain development analysis using iPS cells and genome editing technologiesPrincipal Investigator

    • Principal Investigator
      Ishikawa Mitsuru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      Keio University
  •  Functional analysis of synapse morphology regulated by MKL, an actin-binding coactivatorPrincipal Investigator

    • Principal Investigator
      ISHIKAWA Mitsuru
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Biological pharmacy
    • Research Institution
      University of Toyama

All 2021 2020 2019 2016 2015 2014 2011

All Journal Article Presentation

  • [Journal Article] Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region.2021

    • Author(s)
      1.Ikegame T, Hidaka Y, Nakachi Y, Murata Y, Watanabe R, Sugawara H, Asai T, Kiyota E, Saito T, Ikeda M, Sasaki T, Hashimoto M, Ishikawa T, Takebayashi M, Iwata N, Kakiuchi C, Kato T, Kasai K, Bundo M, Iwamoto K
    • Journal Title

      Transl Psychiatry.

      Volume: 11;11(1) Issue: 1 Pages: 119-119

    • DOI

      10.1038/s41398-021-01242-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15486, KAKENHI-INTERNATIONAL-16K21720, KAKENHI-PLANNED-18H05435, KAKENHI-PROJECT-19K17056, KAKENHI-PLANNED-16H06399, KAKENHI-PLANNED-18H05430, KAKENHI-PROJECT-18H02753, KAKENHI-PROJECT-18H02756
  • [Journal Article] miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro2020

    • Author(s)
      Ishikawa Mitsuru、Aoyama Takeshi、Shibata Shoichiro、Sone Takefumi、Miyoshi Hiroyuki、Watanabe Hirotaka、Nakamura Mari、Morota Saori、Uchino Hiroyuki、Yoo Andrew S.、Okano Hideyuki
    • Journal Title

      Cells

      Volume: 9 Issue: 3 Pages: 532-532

    • DOI

      10.3390/cells9030532

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08668, KAKENHI-PROJECT-17K10083
  • [Journal Article] In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN2019

    • Author(s)
      Ishii Takaya、Ishikawa Mitsuru、Fujimori Koki、Maeda Takuji、Kushima Itaru、Arioka Yuko、Mori Daisuke、Nakatake Yuhki、Yamagata Bun、Nio Shintaro、Kato Takahiro A.、Yang Nan、Wernig Marius、Kanba Shigenobu、Mimura Masaru、Ozaki Norio、Okano Hideyuki
    • Journal Title

      eNEURO

      Volume: 6 Issue: 5 Pages: 0403-18

    • DOI

      10.1523/eneuro.0403-18.2019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H04042, KAKENHI-PROJECT-17H05090, KAKENHI-PROJECT-17K10083
  • [Journal Article] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016

    • Author(s)
      Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
    • Journal Title

      Stem Cell Reports

      Volume: 6 Issue: 4 Pages: 496-510

    • DOI

      10.1016/j.stemcr.2016.02.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-25430055, KAKENHI-PROJECT-26830018, KAKENHI-PROJECT-15H04278, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199, KAKENHI-PLANNED-26117007, KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K07247
  • [Journal Article] Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells2016

    • Author(s)
      Matsumoto T, Fujimori K, Andoh-Noda T, Ando T, Kuzumaki N, Toyoshima M, Tada H, Imaizumi K, Ishikawa M, Yamaguchi R, Isoda M, Zhou Z, Sato S, Kobayashi T, Ohtaka M, Nishimura K, Kurosawa H, Yoshikawa T, Takahashi T, Nakanishi M, Ohyama M, Hattori N, Akamatsu W, Okano H.
    • Journal Title

      Stem Cell Reports.

      Volume: 6 Issue: 3 Pages: 422-35

    • DOI

      10.1016/j.stemcr.2016.01.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06780, KAKENHI-PROJECT-15K09849, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-26830018, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-26870074, KAKENHI-ORGANIZER-24116001, KAKENHI-PROJECT-16K08280
  • [Journal Article] Cellular localization and dendritic function of rat isoforms of the SRF coactivator MKL1 in cortical neurons.2014

    • Author(s)
      Ishikawa M, Shiota J, Ishibashi Y, Hakamata T, Shoji S, Fukuchi M, Tsuda M, Shirao T, Sekino Y, Baraban JM, Tabuchi A.
    • Journal Title

      Neuroreport.

      Volume: 25 Issue: 8 Pages: 585-92

    • DOI

      10.1097/wnr.0000000000000141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460064, KAKENHI-PROJECT-26830018
  • [Presentation] Rapid, robust, and subtype-specific neuronal differentiation from human pluripotent stem cells for multi-dimensional screening of neurodevelopmental / psychiatric disorders2020

    • Author(s)
      Ishikawa M
    • Organizer
      The 10th Takeda Science Foundation Symposium on PharmaSciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10083
  • [Presentation] Cellular Modeling of a Neurodevelopmental Disorder using Functionally Matured Human Excitatory / Inhibitory Neurons2019

    • Author(s)
      Ishikawa M and Okano H
    • Organizer
      Neuro2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K10083
  • [Presentation] iPS細胞を利用した創薬の未来を語ろう:疾患iPS細胞を使って選抜した薬物でのALSの医師主導治験2019

    • Author(s)
      石川充
    • Organizer
      第10回 スクリーニング学研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K10083
  • [Presentation] Widespread analysis of TSSs in human iPSC-derived neurons using CAGE-SEQ2016

    • Author(s)
      石川充
    • Organizer
      日本神経科学大会
    • Place of Presentation
      パシフィコ横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-26830018
  • [Presentation] 神経フェリチン症(Neuroferritinopathy)患者由来iPS細胞の樹立と病態モデルの検討2015

    • Author(s)
      森本悟、石川充、西田勝也、岡本理志、駒野肇、赤松和土、Holly J Garringer、Vidal Ruben、白石泰三、高尾昌樹、岡野栄之
    • Organizer
      第14回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-26830018
  • [Presentation] Molecular and functional characterization of Angelman syndrome patient-derived iPSCs and neurons2015

    • Author(s)
      Mitsuru Ishikawa, Hironobu Okuno, Shoma Tanaka, Yuki Nakatake, Wado Akamatsu, Shinji Saitoh, Kenjiro Kosaki, Minoru Ko, Hideyuki Okano
    • Organizer
      29th International Mammalian Genome Conference
    • Place of Presentation
      横浜開港記念館(神奈川県横浜市)
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830018
  • [Presentation] Expression analysis of imprinted genes in Angelman syndrome patient derived-iPSCs and iPSCs-derived neurons2015

    • Author(s)
      Mitsuru Ishikawa, Hironobu Okuno, Shoma Tanaka, Wado Akamatsu, Shinji Saitoh, Kenjiro Kosaki, Hideyuki Okano
    • Organizer
      The 11th International Workshop on Advanced Genomics
    • Place of Presentation
      一ツ橋ホール(東京都千代田区)
    • Year and Date
      2015-05-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26830018
  • [Presentation] ヒトiPS細胞由来神経細胞における活動依存的遺伝子発現機構の解析2015

    • Author(s)
      石川充、赤松和土、駒野肇、岡野栄之
    • Organizer
      第14回日本再生医療学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-26830018
  • [Presentation] ヒトiPS細胞由来興奮性ニューロン分化誘導技術を用いた神経発達障害における遺伝子発現と細胞形態解析2015

    • Author(s)
      石川充、奥野博庸、田中翔真、中武悠樹、赤松和土、小崎健次郎、齋藤伸治、洪実、岡野栄之
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸コンベンションセンター (兵庫県神戸市)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26830018
  • [Presentation] an actin-binding coactivator for SRF, is involved in a novel signaling pathway for activin-regulated dendritic morphology in rat cortical neurons2011

    • Author(s)
      石川充
    • Organizer
      The 6th International Conference of Neurons and Brain Disease
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-23890065
  • [Presentation] Identification and characterization of a novel transcript of rat MKL1, the actin-binding coactivator for SRF : the effect on transcriptional activation and neuronal morphology in rat cortical neurons2011

    • Author(s)
      石川充
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-23890065
  • [Presentation] Identification and characterization of a novel transcript of rat MKL1, the actin-binding coactivator for SRF : the effect on transcriptional activity and neuronal morphology in rat cortical neurons2011

    • Author(s)
      石川充
    • Organizer
      第34回日本分子神経生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-23890065
  • [Presentation] MKL, an actin-binding coactivator for SRF, is involved in a novel signa-ling pathway for activin-regulated dendritic morphology in rat cortical neurons2011

    • Author(s)
      石川充
    • Organizer
      The 6^<th> International Conference of Neurons and Brain Diseases
    • Place of Presentation
      ANAクラウンプラザホテル(富山)
    • Data Source
      KAKENHI-PROJECT-23890065
  • [Presentation] アクチン結合性転写活性化因子MKLが関与するアクチビン誘導性のラット大脳皮質ニューロン樹状突起形態制御における新規シグナル伝達経路の解析2011

    • Author(s)
      石川充
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-23890065
  • [Presentation] アクチン結合性転写活性化因子MKLが関与するアクチビン誘導性のラット大脳皮質ニューロン樹状突起形態制御における新規シグナル伝達経路の解析2011

    • Author(s)
      石川充
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Data Source
      KAKENHI-PROJECT-23890065
  • 1.  Kato Tadafumi (30214381)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  吉川 武男 (30249958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  森本 昌史 (10285265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  千代延 友裕 (40571659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TANAKA Shoma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  FUKUCHI Mamoru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  SUGAWARA Hiroko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  KATO Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  田渕 明子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  曽根 岳史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  渡部 博貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  佐藤 栄人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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