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Toritsuka Michihiro  鳥塚 通弘

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TORITSUKA Michihiro  鳥塚 通弘

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Researcher Number 20588529
Other IDs
Affiliation (Current) 2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2024 – 2025: 藤田医科大学, 医学部, 講師
2021 – 2023: 奈良県立医科大学, 医学部, 講師
2022: 奈良県立医科大学, 医学部, 学内講師
2017 – 2020: 奈良県立医科大学, 医学部, 学内講師
2014 – 2017: 奈良県立医科大学, 医学部, 助教
2011 – 2012: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 52030:Psychiatry-related / Psychiatric science
Except Principal Investigator
Basic Section 52030:Psychiatry-related / Psychiatric science
Keywords
Principal Investigator
iPS細胞 / 統合失調症 / マクロファージ / ヒトiPS細胞 / 培養系 / シナプス / 炎症 / T細胞 / 炎症性サイトカイン / 自閉スペクトラム症 … More / hiPS細胞 / ASD / 補体 / プルーニング / 細胞培養 / 細胞生物学 / 抗精神病薬 … More
Except Principal Investigator
ミクログリア / マクロファージ / 自閉スペクトラム症 / 思春期 / 貪食能 / 貪食 / 治療抵抗性 / 統合失調症 / ミエリン / 運動 / 小児期体験 / マウス / 脂質 / 小児期 / 脂肪酸 / 髄鞘形成 / 社会性 / 社会行動 / 前頭前野 / 髄鞘 / 炎症 / オレイン酸 / エライジン酸 / 栄養 / サイトカイン / TNF-α / トランスレーショナルリサーチ / 分子神経免疫 / 神経性無食欲症 / 神経炎症 / ERP / 腸内フローラ / 糞便移植 / 思春期やせ症 / 近赤外線スペクトロスコピィ / 事象関連電位 / 摂食障害 / ユースメンタルヘルス / 脳腸相関 / 思春期メンタルヘルス / 神経性やせ症 Less
  • Research Projects

    (12 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (20 People)
  •  ヒトiPS細胞由来マイクログリアの貪食能に着目した自閉スペクトラム症の病態解析Principal Investigator

    • Principal Investigator
      鳥塚 通弘
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Fujita Health University
  •  A study to predict the prognosis of adolescent onset schizophrenia from the perspective of myelination

    • Principal Investigator
      牧之段 学
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Fujita Health University
  •  Research on the phagocytic ability of macrophages in autism spectrum disorders

    • Principal Investigator
      山内 崇平
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Nara Medical University
  •  免疫系細胞とヒトiPSニューロン共培養系によるASDの病態解析Principal Investigator

    • Principal Investigator
      鳥塚 通弘
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Nara Medical University
  •  Research focusing on macrophage dysfunction in autism spectrum disorders

    • Principal Investigator
      YAMAUCHI Takahira
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Nara Medical University
  •  Childhood nutrition-dependent myelin structure and its effects on psychiatric symptoms

    • Principal Investigator
      Makinodan Manabu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Nara Medical University
  •  Pathophysiological analysis of schizophrenia and ASD by using the co-culture system of macrophages and hiPSC-derived neurons.Principal Investigator

    • Principal Investigator
      Toritsuka Michihiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Nara Medical University
  •  Identification of the psychobiotics in young patients with anorexia nervosa by multidimensional analysis: Toward the discovery of therapeutic agents

    • Principal Investigator
      Toshifumi Kishimoto
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Nara Medical University
  •  注意欠如多動症と自閉スペクトラム症併存の神経基盤の解明と治療効果予測を目指して

    • Principal Investigator
      山室 和彦
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Nara Medical University
  •  Analyzing synaptic pathology of schizophrenia by using the iPS cell derived neuronal culture.Principal Investigator

    • Principal Investigator
      Toritsuka Michihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Nara Medical University
  •  Analysis of induced pluripotent stem cell derived-neurons of patients with schizophrenia in vitro and in vivoPrincipal Investigator

    • Principal Investigator
      Toritsuka Michihiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Nara Medical University
  •  Establishment of in vitro research system for psychiatric disorders by using the iPS cell technologyPrincipal Investigator

    • Principal Investigator
      TORITSUKA Michihiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Nara Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines2024

    • Author(s)
      Takada Ryohei、Toritsuka Michihiro、Yamauchi Takahira、Ishida Rio、Kayashima Yoshinori、Nishi Yuki、Ishikawa Mitsuru、Yamamuro Kazuhiko、Ikehara Minobu、Komori Takashi、Noriyama Yuki、Kamikawa Kohei、Saito Yasuhiko、Okano Hideyuki、Makinodan Manabu
    • Journal Title

      Molecular Autism

      Volume: 15 Issue: 1 Pages: 10-10

    • DOI

      10.1186/s13229-024-00589-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07586, KAKENHI-PROJECT-23K07018
  • [Journal Article] Tumor necrosis factor-α expression aberration of M1/M2 macrophages in adult high-functioning autism spectrum disorder.2021

    • Author(s)
      Yamauchi T, Makinodan M, Toritsuka M, Okumura K, Kayashima Y, Ishida R, Kishimoto N, Takahashi M, Komori T, Yamaguchi Y, Takada R, Yamamuro K, Kimoto S, Yasuda Y, Hashimoto R, Kishimoto T
    • Journal Title

      Autism Research

      Volume: 14 Issue: 11 Pages: 2330-2341

    • DOI

      10.1002/aur.2585

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18K07609
  • [Journal Article] iPS細胞の活用による精神科診療の変化の可能性2017

    • Author(s)
      鳥塚通弘、岸本年史
    • Journal Title

      精神科

      Volume: 30 Pages: 245-249

    • Data Source
      KAKENHI-PROJECT-16K10191
  • [Presentation] 自閉スペクトラム症患者由来マクロファージにおける貪食能の評価2024

    • Author(s)
      西佑記、高田涼平、鳥塚通弘、石田理緒、萱島善徳、神川浩平、竹田奬、石川充、山内崇平、岡野栄之、牧之段学
    • Organizer
      第45回日本生物学的精神医学会年会
    • Data Source
      KAKENHI-PROJECT-22K07586
  • [Presentation] 自閉スペクトラム症者由来マクロファージにおける貪食能の評価2023

    • Author(s)
      西 佑記、高田 涼平、鳥塚 通弘、石田 理緒、萱島 善徳、神川 浩平、竹田 奨、石川 充、山内 崇平、岡野 栄之、牧之段 学
    • Organizer
      第45回日本生物学的精神医学会年会
    • Data Source
      KAKENHI-PROJECT-23K07018
  • [Presentation] Cellular analysis of Autism Spectrum Disorder using co culture system of hiPSC derived neurons and macrophage s from patients2022

    • Author(s)
      Ryohei Takada 1 , Michihiro Toritsuka 1 Takahira Yamauchi 1 , Yoshinori Kayashima 1 , Rio Ishida 1 Yuki Nish i 1 Hiroaki Fukui 1 , Mitsuru Ishikawa 2 , Hideyuki Okano 2 , and Manabu Makinodan 1
    • Organizer
      ISN-APSN meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07586
  • [Presentation] TNF-α expression ratio of M1/M2 macrophages is a potential adjunctive tool for the diagnosis of autism spectrum disorder2022

    • Author(s)
      山内崇平 牧之段学 奥村和生 萱嶋善徳 高田涼平 鳥塚通弘 岸本年史
    • Organizer
      第43回生物学的精神医学会、第51回日本神経精神薬理学会、合同年会
    • Data Source
      KAKENHI-PROJECT-18K07609
  • [Presentation] ヒト細胞リソースを用いた精神疾患研究2022

    • Author(s)
      鳥塚通弘
    • Organizer
      BPCNPNPPP4学会合同年会
    • Data Source
      KAKENHI-PROJECT-22K07586
  • [Presentation] Tumor necrosis factor-α expression aberration of M1/M2 macrophages in adult high-functioning autism spectrum disorder2022

    • Author(s)
      Takahira Yamauchi, Michihiro Toritsuka, Kazuki Okumura, Yoshinori Kayashima, Rio Ishida, Takashi Komori, Yasunari Yamaguchi, Ryohei Takada, Kazuhiko Yamamuro, Sohei Kimoto, Toshifumi Kishimoto, Manabu Makinodan
    • Organizer
      第64回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-18K07609
  • [Presentation] TNF-α expression ratio of M1/M2 macrophages is a potential adjunctive tool for the diagnosis of autism spectrum disorder2021

    • Author(s)
      山内崇平 牧之段学 奥村和生 萱嶋善徳 高田涼平 鳥塚通弘 岸本年史
    • Organizer
      第43回生物学的精神医学会、第51回日本神経精神薬理学会、合同年会
    • Data Source
      KAKENHI-PROJECT-18K07609
  • [Presentation] ヒト細胞リソースを用いた精神疾患研究2021

    • Author(s)
      鳥塚通弘
    • Organizer
      第42回日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08025
  • [Presentation] ヒト細胞リソースを用いた精神疾患研究2020

    • Author(s)
      鳥塚通弘
    • Organizer
      NPBPPP2020合同年会
    • Data Source
      KAKENHI-PROJECT-19K08025
  • [Presentation] 精神科医が実践する ウェットな精神医学研究アプローチ2020

    • Author(s)
      鳥塚通弘
    • Organizer
      NPBPPP2020合同年会
    • Data Source
      KAKENHI-PROJECT-19K08025
  • [Presentation] ヒト細胞リソースを用いた精神疾患研究2019

    • Author(s)
      鳥塚通弘
    • Organizer
      第41回日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-19K08025
  • [Presentation] ヒト細胞リソースを用いた精神疾患研究2018

    • Author(s)
      鳥塚通弘
    • Organizer
      第40回日本生物学的精神医学会・第61回日本神経化学会大会
    • Data Source
      KAKENHI-PROJECT-16K10191
  • [Presentation] ヒト細胞リソースを用いた精神疾患研究2017

    • Author(s)
      鳥塚通弘
    • Organizer
      第39回日本生物学的精神医学会・第47回日本神経精神薬理学会
    • Data Source
      KAKENHI-PROJECT-16K10191
  • [Presentation] iPS細胞を用いた統合失調症双子不一致症例の解析2017

    • Author(s)
      鳥塚通弘
    • Organizer
      第39回日本生物学的精神医学会・第47回日本神経精神薬理学会
    • Data Source
      KAKENHI-PROJECT-16K10191
  • [Presentation] The cellular analysis of schizophrenia by using iPSC-derived neurons2016

    • Author(s)
      Michihiro Toritsuka
    • Organizer
      REGIONAL LATIN AMERICAN CONGRESS OF THE WORLD FEDERATION OF SOCIETIES OF BIOLOGICAL PSYCHIATRY.
    • Place of Presentation
      PLAZA DEL BOSQUE HOTEL
    • Year and Date
      2016-11-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10191
  • [Presentation] Induced pluripotent stem cells-derived neurons of the patients with discordant schizophrenia2015

    • Author(s)
      鳥塚通弘、他17名
    • Organizer
      第58回日本神経化学会
    • Place of Presentation
      大宮ソニックシティ
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26860940
  • 1.  山室 和彦 (60526721)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 2.  Makinodan Manabu (00510182)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  YAMAUCHI Takahira (20550817)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 4.  紀本 創兵 (00405391)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  松岡 究 (80613794)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  芳野 浩樹 (10347560)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  太田 豊作 (10553646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Toshifumi Kishimoto (60201456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  井川 大輔 (00526717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  宮坂 俊輝 (00771023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  北村 聡一郎 (10714389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  矢野 寿一 (20374944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  栗本 一基 (20415152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  末次 志郎 (70345031)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  國井 泰人 (00511651)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  星野 歩子 (00819964)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  峠 隆之 (30415236)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  木村 大樹 (30612783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  橋本 亮太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  高田 昌彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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