Yoshino Hiroki 芳野浩樹

… Alternative Names

芳野浩樹ヨシノヒロキ

YOSHINO Hiroaki 芳野浩樹

Less

Researcher Number	10347560
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 奈良県立医科大学, 医学部, 研究員 2021: 奈良県立医科大学, 医学部, 准教授 2019: 奈良県立医科大学, 医学部, 博士研究員 2018 – 2019: 奈良県立医科大学, 医学部, 准教授 2013 – 2017: 奈良県立医科大学, 医学部, 講師 … More 2008: 奈良県立医大, 医学部, 助教 2007: Nara Medical University, 医学部, 助教 2003 – 2005: 奈良県立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related Except Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator 錐体細胞 / 前頭前野 / 社会的経験 / 興奮性 / 社会経験 / 内側前頭前野 / 社会的隔離 / 発達 / 前頭葉 / GABA … More / prefrontal cortex / periaqueductal gray / excitability / social experience / 活動電位 / 興奮性シナプス / 小脳 / 橋 / 孤立 / 社会性 / 電気生理 / 神経科学 / 精神疾患 / 神経発達 / 隔離 / 介在ニューロン / 抑制性 / 興奮性シナプス伝達 / 膜興奮性 / 興奮性後シナプス電流 / h-current / 神経細胞 / 統合失調症 / 海馬 / ドパミン … More Except Principal Investigator 統合失調症 / radiation / repair / DNA damage / 放射線 / DDB1 / 修復 / DNA損傷 / トランスレーショナルリサーチ / 分子神経免疫 / 神経性無食欲症 / 神経炎症 / ERP / 腸内フローラ / 糞便移植 / 思春期やせ症 / 近赤外線スペクトロスコピィ / 事象関連電位 / 摂食障害 / 思春期 / ユースメンタルヘルス / 脳腸相関 / 思春期メンタルヘルス / 神経性やせ症 / hiPS細胞 / ASD / マクロファージ / ヒトiPS細胞 / 補体 / プルーニング / 培養系 / シナプス / iPS細胞 / 恐怖記憶 / 前頭前野機能 / 自閉症 / ミエリン / 認知リハビリテーション / MRI / 社会的経験 / 髄鞘形成 / 社会性 / リハビリテーション / 小児期体験 / 前頭前野 / 自閉スペクトラム症 / astrocyte / DSB / neuron / gamma H2AX / double strand break / アストロサイト / 二本鎖切断 / 神経細胞 / γ-H2AX / UV / fluorescent protein / chaperon / oxidative stress / シャペロン / 紫外線 / 蛍光蛋白 / シャペロ / 酸化的ストレス Less

社会的経験により発達する前頭前野-小脳回路の解明　中脳水道周囲灰白質を中心にPrincipal Investigator
- Principal Investigator
  
  芳野浩樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
Pathophysiological analysis of schizophrenia and ASD by using the co-culture system of macrophages and hiPSC-derived neurons.
- Principal Investigator
  
  Toritsuka Michihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
Identification of neural circuit responsible social function in social isolation animal model : focusing on medial prefrontal cortex - pons - cerebellumPrincipal Investigator
- Principal Investigator
  
  Yoshino Hiroki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
Identification of the psychobiotics in young patients with anorexia nervosa by multidimensional analysis: Toward the discovery of therapeutic agents
- Principal Investigator
  
  Toshifumi Kishimoto
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
Dissecting the prefrontal cortex dysfunction and its recovery in autism spectrum disorder.
- Principal Investigator
  
  Makinodan Manabu
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Analyzing synaptic pathology of schizophrenia by using the iPS cell derived neuronal culture.
- Principal Investigator
  
  Toritsuka Michihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Local excitatory / inhibitory neuronal circuit in prefrontal cortex developed by social experience can be a target for treatment?Principal Investigator
- Principal Investigator
  
  Yoshino Hiroki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
The research of social experience-dependent development of prefrontal excitatory neural circuit for psychiatric treatmentPrincipal Investigator
- Principal Investigator
  
  Yoshino Hiroki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
統合失調症母体ウイルス感染モデルマウスのシナプス伝達に対するドパミンの効果Principal Investigator
- Principal Investigator
  
  芳野浩樹
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -
- Principal Investigator
  
  KISHIMOTO Toshifumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells
- Principal Investigator
  
  NAKAMURA Yu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University

All 2023 2022 2020 2019 2017 2016 2015 2007 2006 Other

All Journal Article Presentation

[Journal Article] Juvenile social isolation immediately affects the synaptic activity and firing property of fast-spiking parvalbumin-expressing interneuron subtype in mouse medial prefrontal cortex2022
- Author(s)
  Okamura Kazuya、Yoshino Hiroki、Ogawa Yoichi、Yamamuro Kazuhiko、Kimoto Sohei、Yamaguchi Yasunari、Nishihata Yosuke、Ikehara Minobu、Makinodan Manabu、Saito Yasuhiko、Kishimoto Toshifumi
- Journal Title
  
  Cerebral Cortex
  
  Volume: 33 Issue: 7 Pages: 3591-3606
- DOI
  10.1093/cercor/bhac294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06424, KAKENHI-PROJECT-20H03604, KAKENHI-PROJECT-19K08078, KAKENHI-PROJECT-19K17117
[Journal Article] 社会経験の剥奪による内側前頭前野の興奮性/抑制性バランスの異常2020
- Author(s)
  芳野　浩樹
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: ４ Pages: 174-178
- NAID
  130007961376
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08078
[Journal Article] Juvenile Social Isolation Enhances the Activity of Inhibitory Neuronal Circuits in the Medial Prefrontal Cortex.2020
- Author(s)
  Yamamuro K, Yoshino H, Ogawa Y, Okamura K, Nishihata Y, Makinodan M, Saito Y, Kishimoto T
- Journal Title
  
  Front Cell Neurosci
  
  Volume: 14 Pages: 105-105
- DOI
  10.3389/fncel.2020.00105
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-20H03604, KAKENHI-PROJECT-18K06524
[Journal Article] Social Isolation During the Critical Period Reduces Synaptic and Intrinsic Excitability of a Subtype of Pyramidal Cell in Mouse Prefrontal Cortex.2017
- Author(s)
  Yamamuro K, Yoshino H, Ogawa Y, Makinodan M, Toritsuka M, Yamashita M, Corfas G, Kishimoto T.
- Journal Title
  
  Cereb Cortex.
  
  Volume: 1-13 Issue: 3 Pages: 998-1010
- DOI
  10.1093/cercor/bhx010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06400, KAKENHI-PROJECT-16K10221, KAKENHI-PROJECT-15K15432
[Journal Article] Effects of cross-rearing with social peers on myelination in the medial prefrontal cortex of a mouse model with autism spectrum disorder2017
- Author(s)
  Makinodan M. Okumura K. Ikawa D. Yamashita Y. Yamamuro K. Toritsuka M. Kimoto S. Yamauchi T. Komori T. Kayashima Y. Yoshino H. Wanaka A. Kishimoto T.
- Journal Title
  
  Heliyon
  
  Volume: 3 Issue: 11 Pages: e00468-e00468
- DOI
  10.1016/j.heliyon.2017.e00468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10339, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-15K14354
[Journal Article] Effects of the mode of re-socialization after juvenile social isolation on medial prefrontal cortex myelination and function2017
- Author(s)
  Makinodan M. Ikawa D. Yamamuro K. Yamashita Y. Torituka M. Kimoto S. Okumura K. Komori T. Fukami S. Yoshino H. Kanba S. Wanaka A. Kishimoto T
- Journal Title
  
  Sci.Rep
  
  Volume: 14 Issue: 1 Pages: 5481-5481
- DOI
  10.1038/s41598-017-05632-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10339, KAKENHI-PROJECT-15K15432, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-15K14354
[Journal Article] Dopamine profoundly suppresses excitatory transmission in neonatal rat hippocampus via phosphatidylinositol-linked d1-like receptor2006
- Author(s)
  Y.Noriyama, Y.Ogawa, H.Yoshino, M.Yamashita, T.Kishimoto
- Journal Title
  
  Neuroscience 138
  
  Pages: 475-485
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591155
[Journal Article] Dopamine profoundly suppresses excitatory transmission in neonatal rat hippocampus via phosphatidylinositol-linked d1-like receptor2006
- Author(s)
  Y.Noriyama, Y.Ogawa, H.Yoshino, M.Yamashita, T.Kishimoto.
- Journal Title
  
  Neuroscience 138
  
  Pages: 475-485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591155
[Presentation] Juvenile social isolation affects synaptic and intrinsic excitability of prefronatal cortex layer 5 pyramidal cells with subcortical axonal projection2023
- Author(s)
  Hiroki Yoshino Yosuke Nishihata Yoichi Ogawa Taketoshi Sugimura Kazuya Okamura Kazuhiko Yamamuro Manabu Makinodan Ysuhiko Saito Toshifumi Kishimoto
- Organizer
  Society for Neuroscience 2023 Washington DC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07040
[Presentation] Social Isolation during development Reduces Excitability of a Subtype of Pyramidal cell in mouse Prefrontal Cortex which projects to Subcortical areas2019
- Author(s)
  Yosuke Nishihata, Hiroki Yoshino, Yoichi Ogawa, Taketoshi Sugimura, Kazuya Okamura, Kazuhiko Yamamuro, Manabu Makinodan, Michihiro Toritsuka, Takashi Komori, Tokei Kaneda,　Yasuhiko Saito, Toshifumi Kishimoto
- Organizer
  Society for Neuroscience meeting, Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08078
[Presentation] Social isolation during developmental critical window affects inhibitory neuronal circuit in mouse mPFC2019
- Author(s)
  Hiroki Yoshino, Kazuhiko Yamamuro, Yoichi Ogawa, Manabu Makinodan, Yasuhiko Saito, Toshifumi Kishimoto
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies congress, Kobe, 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] Social isolation during the critical period reduces synaptic and intrinsic excitability of a subtype of pyramidal cell in mouse prefrontal cortex2017
- Author(s)
  H. YOSHINO, K. YAMAMURO, Y. OGAWA, M. MAKINODAN, M. TORITSUKA, K. OKAMURA, Y. NISHIHATA, Y. YAMAGUCHI, S. KIMOTO, M. YAMASHITA, G. CORFAS, T. KISHIMOTO
- Organizer
  Society for Neuroscience 47th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] 社会的隔離はマウス前頭前野の特定の錐体細胞の興奮性を低下させる2017
- Author(s)
  芳野浩樹、山室和彦、小川陽一、鳥塚通弘、岡村和哉、西畑陽介、山口泰成、紀本創兵、山下勝幸、Corfas　Gabriel、牧之段学、岸本年史
- Organizer
  第39回日本生物学的精神医学会　第47回日本神経精神薬理学会　合同年会
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] Lack of Social Experience Disrupts E/I Balance in Medial Prefrontal Cortex2016
- Author(s)
  Hiroki Yoshino
- Organizer
  Regional Latin American Congress of The World Federation of Societies of Biological Psychiatry 2016
- Place of Presentation
  Lima, Peru
- Year and Date
  2016-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] Social isolation during the critical period affects excitatory neuronal activity in mouse medial prefrontal cortex2015
- Author(s)
  Yamamuro K, Yoshino H, Ogawa Y, Okamura Y, Nishihata Y, Saito Y, Kishimoto T
- Organizer
  Society for neuroscience 45th annual meeting
- Place of Presentation
  Chicago
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] 神経細胞の電気活動から精神疾患へ2015
- Author(s)
  芳野　浩樹
- Organizer
  第111回日本精神神経学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] Social isolation during the critical period and excitatory neuronal activity in mouse medial prefrontal cortex2015
- Author(s)
  Yoshino H, Yamamuro K, Ogawa Y, Okamura K, Saito Y, Kishimoto T
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] Increases of spontaneous GABA-PSCs by dopajtnine in neonatal mouse2007
- Author(s)
  芳野浩樹
- Organizer
  Society for Neuroscience 2007 37th
- Place of Presentation
  San Diego U.S.A.
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19790832
[Presentation] Increase in the frequency of spontaneous GABAA-PSC by dopamine inneonatal mouse hippocampus2007
- Author(s)
  芳野浩樹
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19790832
[Presentation] 新生マウス海馬でのドパミンによる自発性GABA作動性シナプス後電流の頻度の増加2007
- Author(s)
  芳野浩樹
- Organizer
  第16回海馬と高次機脳学会
- Place of Presentation
  奈良
- Year and Date
  2007-11-25
- Data Source
  KAKENHI-PROJECT-19790832
[Presentation] 臨界期の社会的孤立によるマウス内側前頭前野皮質の興奮性シナプス伝達の減弱
- Author(s)
  山室　和彦、芳野　浩樹、小川　陽一、岡村　和哉、齋藤　康彦、岸本　年史
- Organizer
  第92回日本生理学会大会　第120回日本解剖学会総会全国学術総会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] Chronic social isolation reduces excitatory synaptic inputs in medial prefrontal cortex
- Author(s)
  K. Yamamuro, H.Yoshino, Y. Ogawa, M. Makinodan, C.Gabriel, T. Kishimoto
- Organizer
  44th Annual meeting of Society for neuroscience
- Place of Presentation
  Washington DC USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] 臨界期の社会的隔離とマウス内側前頭前野皮質の興奮性神経活動
- Author(s)
  芳野　浩樹、山室　和彦、小川　陽一、岡村　和哉、齋藤　康彦、岸本　年史
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] 社会的孤立によるマウス内側前頭前皮質の興奮性シナプス伝達の減弱
- Author(s)
  山室　和彦、芳野　浩樹、小川　陽一、牧之段　学、岸本　年史
- Organizer
  第36回日本生物学的精神学会　第57回日本神経化学会大会　合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25461778

1. MAKINODAN Manabu (00510182)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. KISHIMOTO Toshifumi (60201456)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. Toritsuka Michihiro (20588529)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUGIURA Sigeki (40179130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKAMURA Yu (70291440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MORI Toshio (10115280)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 紀本創兵 (00405391)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 太田豊作 (10553646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 安野史彦 (60373388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松田康裕 (70445063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 井川大輔 (00526717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宮坂俊輝 (00771023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 北村聡一郎 (10714389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 矢野寿一 (20374944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松岡究 (80613794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山内崇平 (20550817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 斎藤康彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 山室和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yoshino Hiroki 芳野 浩樹

芳野 浩樹 ヨシノ ヒロキ

YOSHINO Hiroaki 芳野 浩樹

Research Projects

Research Products

Co-Researchers

社会的経験により発達する前頭前野-小脳回路の解明 中脳水道周囲灰白質を中心にPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological analysis of schizophrenia and ASD by using the co-culture system of macrophages and hiPSC-derived neurons.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of neural circuit responsible social function in social isolation animal model : focusing on medial prefrontal cortex - pons - cerebellumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the psychobiotics in young patients with anorexia nervosa by multidimensional analysis: Toward the discovery of therapeutic agents

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dissecting the prefrontal cortex dysfunction and its recovery in autism spectrum disorder.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyzing synaptic pathology of schizophrenia by using the iPS cell derived neuronal culture.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Local excitatory / inhibitory neuronal circuit in prefrontal cortex developed by social experience can be a target for treatment?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The research of social experience-dependent development of prefrontal excitatory neural circuit for psychiatric treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

統合失調症母体ウイルス感染モデルマウスのシナプス伝達に対するドパミンの効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Juvenile social isolation immediately affects the synaptic activity and firing property of fast-spiking parvalbumin-expressing interneuron subtype in mouse medial prefrontal cortex2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 社会経験の剥奪による内側前頭前野の興奮性/抑制性バランスの異常2020

Author(s)

Journal Title

Yoshino Hiroki 芳野浩樹

芳野浩樹ヨシノヒロキ

YOSHINO Hiroaki 芳野浩樹

社会的経験により発達する前頭前野-小脳回路の解明　中脳水道周囲灰白質を中心にPrincipal Investigator