Yoshino Hiroki 芳野浩樹

… Alternative Names

Researcher Number	10347560
Other IDs
Affiliation (Current)	2020: 奈良県立医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2019: 奈良県立医科大学, 医学部, 准教授 2013 – 2018: 奈良県立医科大学, 医学部, 講師 2008: 奈良県立医大, 医学部, 助教 2007: Nara Medical University, 医学部, 助教 2003 – 2005: 奈良県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related Except Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator 社会経験 / 興奮性 / 錐体細胞 / 前頭葉 / 発達 / 前頭前野 / 社会的経験 / 内側前頭前野 / ドパミン / GABA … More Except Principal Investigator DNA損傷 / 修復 / DDB1 / 放射線 / DNA damage / repair / radiation / 統合失調症 / 酸化的ストレス / シャペロ / 蛍光蛋白 / 紫外線 / シャペロン / oxidative stress / chaperon / fluorescent protein / UV / γ-H2AX / 神経細胞 / 二本鎖切断 / アストロサイト / double strand break / gamma H2AX / neuron / DSB / astrocyte / 自閉スペクトラム症 / 前頭前野 / MRI / 認知リハビリテーション / ミエリン / 自閉症 / 前頭前野機能 / 恐怖記憶 / iPS細胞 / シナプス / 培養系 / プルーニング / 補体 / 摂食障害 / 脳腸相関 / 糞便移植 / 神経性やせ症 / 腸内フローラ / 神経炎症 / 神経性無食欲症 / 分子神経免疫 / トランスレーショナルリサーチ / hiPS細胞 / マクロファージ / ASD Less

マクロファージとヒトiPSニューロン共培養系による統合失調症・ASD病態解析Ongoing
- Principal Investigator
  
  鳥塚通弘
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
社会的隔離モデルによる社会性の神経回路の同定　内側前頭前野ー橋ー小脳を中心にPrincipal InvestigatorOngoing
- Principal Investigator
  
  芳野浩樹
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
多次元解析による神経性無食欲症のサイコバイオティクスの同定：治療薬の創発に向けてOngoing
- Principal Investigator
  
  岸本年史
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
自閉スペクトラム症における前頭前野機能の多面的解析とその正常化への試みOngoing
- Principal Investigator
  
  牧之段学
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Analyzing synaptic pathology of schizophrenia by using the iPS cell derived neuronal culture.
- Principal Investigator
  
  Toritsuka Michihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Local excitatory / inhibitory neuronal circuit in prefrontal cortex developed by social experience can be a target for treatment?Principal Investigator
- Principal Investigator
  
  Yoshino Hiroki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
The research of social experience-dependent development of prefrontal excitatory neural circuit for psychiatric treatmentPrincipal Investigator
- Principal Investigator
  
  Yoshino Hiroki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
統合失調症母体ウイルス感染モデルマウスのシナプス伝達に対するドパミンの効果Principal Investigator
- Principal Investigator
  
  芳野浩樹
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -
- Principal Investigator
  
  KISHIMOTO Toshifumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells
- Principal Investigator
  
  NAKAMURA Yu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University

All 2019 2018 2017 2016 2015 2007 2006 Other

All Journal Article Presentation

[Journal Article] Effects of the mode of re-socialization after juvenile social isolation on medial prefrontal cortex myelination and function.2018
- Author(s)
  Makinodan M. Ikawa D. Yamamuro K. Yamashita Y. Torituka M. Kimoto S. Okumura K. Komori T. Fukami S. Yoshino H. Kanba S. Wanaka A. Kishimoto T
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Pages: 5481-5481
- DOI
  10.1038/s41598-017-05632-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10339, KAKENHI-PROJECT-15K15432, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-15K14354
[Journal Article] Social isolation during the critical period reduces synaptic and intrinsic excitability of a subtype of prefrontal cortex pyramidal cell2018
- Author(s)
  Yamamuro K, Yoshino H, Ogawa Y, Makinodan M, Toritsuka M, Yamashita M, Corfas G, Kishimoto T.
- Journal Title
  
  Cereb Cortex
  
  Volume: 1-13 Pages: 998-1010
- DOI
  10.1093/cercor/bhx010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06400, KAKENHI-PROJECT-16K10221, KAKENHI-PROJECT-15K15432
[Journal Article] Effects of cross-rearing with social peers on myelination in the medial prefrontal cortex of a mouse model with autism spectrum disorder.2017
- Author(s)
  Makinodan M. Okumura K. Ikawa D. Yamashita Y. Yamamuro K. Toritsuka M. Kimoto S. Yamauchi T. Komori T. Kayashima Y. Yoshino H. Wanaka A. Kishimoto T.
- Journal Title
  
  Heliyon
  
  Volume: 3
- DOI
  10.1016/j.heliyon.2017.e00468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10339, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-15K14354
[Journal Article] Dopamine profoundly suppresses excitatory transmission in neonatal rat hippocampus via phosphatidylinositol-linked d1-like receptor2006
- Author(s)
  Y.Noriyama, Y.Ogawa, H.Yoshino, M.Yamashita, T.Kishimoto.
- Journal Title
  
  Neuroscience 138
  
  Pages: 475-485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591155
[Journal Article] Dopamine profoundly suppresses excitatory transmission in neonatal rat hippocampus via phosphatidylinositol-linked d1-like receptor2006
- Author(s)
  Y.Noriyama, Y.Ogawa, H.Yoshino, M.Yamashita, T.Kishimoto
- Journal Title
  
  Neuroscience 138
  
  Pages: 475-485
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591155
[Presentation] Social isolation during developmental critical window affects inhibitory neuronal circuit in mouse mPFC2019
- Author(s)
  Hiroki Yoshino, Kazuhiko Yamamuro, Yoichi Ogawa, Manabu Makinodan, Yasuhiko Saito, Toshifumi Kishimoto
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies congress, Kobe, 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] 社会的隔離はマウス前頭前野の特定の錐体細胞の興奮性を低下させる2017
- Author(s)
  芳野浩樹、山室和彦、小川陽一、鳥塚通弘、岡村和哉、西畑陽介、山口泰成、紀本創兵、山下勝幸、Corfas　Gabriel、牧之段学、岸本年史
- Organizer
  第39回日本生物学的精神医学会　第47回日本神経精神薬理学会　合同年会
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] Social isolation during the critical period reduces synaptic and intrinsic excitability of a subtype of pyramidal cell in mouse prefrontal cortex2017
- Author(s)
  H. YOSHINO, K. YAMAMURO, Y. OGAWA, M. MAKINODAN, M. TORITSUKA, K. OKAMURA, Y. NISHIHATA, Y. YAMAGUCHI, S. KIMOTO, M. YAMASHITA, G. CORFAS, T. KISHIMOTO
- Organizer
  Society for Neuroscience 47th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] Lack of Social Experience Disrupts E/I Balance in Medial Prefrontal Cortex2016
- Author(s)
  Hiroki Yoshino
- Organizer
  Regional Latin American Congress of The World Federation of Societies of Biological Psychiatry 2016
- Place of Presentation
  Lima, Peru
- Year and Date
  2016-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10221
[Presentation] Social isolation during the critical period affects excitatory neuronal activity in mouse medial prefrontal cortex2015
- Author(s)
  Yamamuro K, Yoshino H, Ogawa Y, Okamura Y, Nishihata Y, Saito Y, Kishimoto T
- Organizer
  Society for neuroscience 45th annual meeting
- Place of Presentation
  Chicago
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] Social isolation during the critical period and excitatory neuronal activity in mouse medial prefrontal cortex2015
- Author(s)
  Yoshino H, Yamamuro K, Ogawa Y, Okamura K, Saito Y, Kishimoto T
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] 神経細胞の電気活動から精神疾患へ2015
- Author(s)
  芳野　浩樹
- Organizer
  第111回日本精神神経学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] Increases of spontaneous GABA-PSCs by dopajtnine in neonatal mouse2007
- Author(s)
  芳野浩樹
- Organizer
  Society for Neuroscience 2007 37th
- Place of Presentation
  San Diego U.S.A.
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19790832
[Presentation] 新生マウス海馬でのドパミンによる自発性GABA作動性シナプス後電流の頻度の増加2007
- Author(s)
  芳野浩樹
- Organizer
  第16回海馬と高次機脳学会
- Place of Presentation
  奈良
- Year and Date
  2007-11-25
- Data Source
  KAKENHI-PROJECT-19790832
[Presentation] Increase in the frequency of spontaneous GABAA-PSC by dopamine inneonatal mouse hippocampus2007
- Author(s)
  芳野浩樹
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19790832
[Presentation] 社会的孤立によるマウス内側前頭前皮質の興奮性シナプス伝達の減弱
- Author(s)
  山室　和彦、芳野　浩樹、小川　陽一、牧之段　学、岸本　年史
- Organizer
  第36回日本生物学的精神学会　第57回日本神経化学会大会　合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] 臨界期の社会的隔離とマウス内側前頭前野皮質の興奮性神経活動
- Author(s)
  芳野　浩樹、山室　和彦、小川　陽一、岡村　和哉、齋藤　康彦、岸本　年史
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] Chronic social isolation reduces excitatory synaptic inputs in medial prefrontal cortex
- Author(s)
  K. Yamamuro, H.Yoshino, Y. Ogawa, M. Makinodan, C.Gabriel, T. Kishimoto
- Organizer
  44th Annual meeting of Society for neuroscience
- Place of Presentation
  Washington DC USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25461778
[Presentation] 臨界期の社会的孤立によるマウス内側前頭前野皮質の興奮性シナプス伝達の減弱
- Author(s)
  山室　和彦、芳野　浩樹、小川　陽一、岡村　和哉、齋藤　康彦、岸本　年史
- Organizer
  第92回日本生理学会大会　第120回日本解剖学会総会全国学術総会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25461778

1. MAKINODAN Manabu (00510182)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. KISHIMOTO Toshifumi (60201456)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. Toritsuka Michihiro (20588529)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUGIURA Sigeki (40179130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKAMURA Yu (70291440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MORI Toshio (10115280)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 紀本創兵 (00405391)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 太田豊作 (10553646)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 安野史彦 (60373388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松田康裕 (70445063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 井川大輔 (00526717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 宮坂俊輝 (00771023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 北村聡一郎 (10714389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 矢野寿一 (20374944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松岡究 (80613794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山内崇平 (20550817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 深見伸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 和中明生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yoshino Hiroki 芳野 浩樹

芳野 浩樹 ヨシノ ヒロキ

YOSHINO Hiroaki 芳野 浩樹

Research Projects

Research Products

Co-Researchers

マクロファージとヒトiPSニューロン共培養系による統合失調症・ASD病態解析Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

社会的隔離モデルによる社会性の神経回路の同定 内側前頭前野ー橋ー小脳を中心にPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多次元解析による神経性無食欲症のサイコバイオティクスの同定：治療薬の創発に向けてOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自閉スペクトラム症における前頭前野機能の多面的解析とその正常化への試みOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyzing synaptic pathology of schizophrenia by using the iPS cell derived neuronal culture.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Local excitatory / inhibitory neuronal circuit in prefrontal cortex developed by social experience can be a target for treatment?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The research of social experience-dependent development of prefrontal excitatory neural circuit for psychiatric treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

統合失調症母体ウイルス感染モデルマウスのシナプス伝達に対するドパミンの効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Attenuated repair of radiation-induced DNA damage in primary neural cells from rat embryonic brains - Implication for generation of integration disorder syndrome -

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of dynamics of DNA damage repair protein DDB1 in oxidative stresses in N2a cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of the mode of re-socialization after juvenile social isolation on medial prefrontal cortex myelination and function.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Social isolation during the critical period reduces synaptic and intrinsic excitability of a subtype of prefrontal cortex pyramidal cell2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of cross-rearing with social peers on myelination in the medial prefrontal cortex of a mouse model with autism spectrum disorder.2017

Author(s)

Journal Title

DOI

Yoshino Hiroki 芳野浩樹

芳野浩樹ヨシノヒロキ

YOSHINO Hiroaki 芳野浩樹

社会的隔離モデルによる社会性の神経回路の同定　内側前頭前野ー橋ー小脳を中心にPrincipal InvestigatorOngoing