Kawai Yusuke 川合佑典

Researcher Number	10709546
Other IDs
Affiliation (Current)	2025: 帯広畜産大学, 畜産学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 帯広畜産大学, 畜産学部, 准教授 2017 – 2022: 帯広畜産大学, 畜産学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 45020:Evolutionary biology-related Except Principal Investigator Basic Section 63030:Chemical substance influence on environment-related / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Medium-sized Section 64:Environmental conservation measure and related fields / Basic Section 39060:Conservation of biological resources-related / Basic Section 49050:Bacteriology-related / Environmental analyses and evaluation and related fields
Keywords	Principal Investigator 分子進化 / 酵素誘導 / 鳥類 / 異物代謝 / UGT / グルクロン酸抱合酵素 Except Principal Investigator シトクロムP450 / 環境化学物質 / 環境汚染物質 / 発生毒性 … More / ゼブラフィッシュ / 薬物動態 / 薬物感受性 / アゾール系抗真菌薬 / 薬物相互作用 / 薬物代謝 / CYP / タンチョウ / 希少鳥類 / 神経伝達物質 / 脂質メディエーター / 神経発生毒性 / 心血管毒性 / ネオニコチノイド系殺虫剤 / ダイオキシン / 抗エストロゲン作用 / 甲状腺ホルモン撹乱 / リン酸エステル系難燃剤 / 拮抗作用 / 複合影響 / 環境エストロゲン / 毒性発現機序 / 統合オミクス / フェロモン / 行動学 / 組織形態学 / 嗅覚 / 形態学 / 組織学 / 鼻腔 / 嗅覚器 / ウミガメ / 化学物質代謝 / xenobiotics / 適応進化 / 硫酸抱合 / グルクロン酸抱合 / 環境適応 / 哺乳類 / 硫酸転移酵素 / グルクロン酸転移酵素 / 鉄獲得 / Aspergillus fumigatus / 金属イオン / ガリウムイオン / シデロフォア / 有害金属イオン / トリアセチルフサリニンC / アスペルギルス・フミガツス / 環境毒性 / in vivo ハイコンテンツイメージング / AOP / 作用機序 / 発達神経毒性 / 化学物質 / 毒性発現機構 / 内分泌撹乱 / 化学物質感受性決定帰国 / 発達神経毒性試験ｎ / バイオマーカー / 化学物質感受性決定機構 / 発達神経毒性試験 / mlAOPコンセプト / ネオニコチノイド / 誘導性肝臓様細胞(iHep) / 誘導性肝臓様細胞（iHep） / 種差 / 化学物質感受性 / SULT / UGT / P450 / トッププレデター / Metabolism / iHep / 野生動物 Less

Development and clinical application of a non-invasive drug sensitivity assessment method for ex situ conservation of threatened avian species
- Principal Investigator
  
  久保田彰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Whole embryo screening and integrated omics approach using zebrafish for unraveling mechanisms underlying chemical toxicities
- Principal Investigator
  
  久保田彰
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Adaptive evolution/change in mammals to exogenous chemicals (xenobiotics)
- Principal Investigator
  
  石塚真由美
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Hokkaido University
ウミガメ類における匂い受容能力と嗅覚コミュニケーションの解明
- Principal Investigator
  
  近藤大輔
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 39060:Conservation of biological resources-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
New Functions Other Than Iron Ion Acquisition Revealed in Triacetylphsalinin C
- Principal Investigator
  
  Toyotome Takahito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
The convergent evolution of metabolic systems in birds and mammals for adaptation to diversification of flowering plantsPrincipal Investigator
- Principal Investigator
  
  Kawai Yusuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 45020:Evolutionary biology-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Assessment of developmental toxicities caused by chemical substances and elucidation of their mechanisms based on the quantitative phenotype screening using small fish
- Principal Investigator
  
  Kubota Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Evaluation of Chemical Susceptibility Diversity by mlAOP Concept and its Application to Understanding Insecticide Poisoning
- Principal Investigator
  
  IKENAKA Yoshinori
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Hokkaido University
Contraction of wild-life iHep cell and development of the evaluation method for metabolism of the top predator
- Principal Investigator
  
  Ikenaka Yoshinori
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Environmental analyses and evaluation and related fields
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Evaluation of anticoagulant rodenticide sensitivity by examining in vivo and in vitro responses in avian species, focusing on raptors.2024
- Author(s)
  K Khidkhan, F Yasuhira, A Saengtienchai, C Kasorndorkbua, R Sitdhibutr, Kohei Ogasawara, H Adachi, YWatanabe, K Saito, Hidefumi Sakai, Kazuo Horikoshi, Hajime Suzuki, Yusuke K. Kawai, Kazuki Takeda, Yared B. Yohannes, Y Ikenaka, BA Rattner, M Ishizuka, SMM Nakayama
- Journal Title
  
  Environmental Pollution.
  
  Volume: 341 Pages: 122837-122837
- DOI
  10.1016/j.envpol.2023.122837
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04919
[Journal Article] Assessment of developmental toxicity and the potential mode of action underlying single and binary exposure to estrogenic endocrine disrupting chemicals in zebrafish (Danio rerio)2024
- Author(s)
  Ahmed Rehab Youssef Salama, Tanoue Rumi, Chen Xing, Kawai Yusuke K., Kubota Akira
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 277 Pages: 109821-109821
- DOI
  10.1016/j.cbpc.2023.109821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ0144, KAKENHI-PROJECT-23K25000
[Journal Article] fficient in vivo and in silico assessments of antiandrogenic potential in zebrafish2023
- Author(s)
  Xing Chen, Masashi Hirano, Hiroshi Ishibashi, Jae Seung Lee, Yusuke K Kawai, Akira Kubota
- Journal Title
  
  Comparative Biochemistry and Physiology Part C
  
  Volume: 264 Pages: 109513-109513
- DOI
  10.1016/j.cbpc.2022.109513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00634, KAKENHI-PROJECT-22KJ0144, KAKENHI-PROJECT-23K25000
[Journal Article] Characteristics of cytochrome P450-dependent metabolism against acetamiprid in the musk shrew (Suncus murinus)2023
- Author(s)
  Shinya So、Kawai Yusuke、Kondo Mitsuki、Nakayama Shouta M.M.、Ishizuka Mayumi、Ikenaka Yoshinori
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology
  
  Volume: 265 Pages: 109537-109537
- DOI
  10.1016/j.cbpc.2022.109537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18425, KAKENHI-PROJECT-21H04919
[Journal Article] In vivo and in silico assessments of estrogenic potencies of bisphenol A and its analogs in zebrafish (Danio rerio): Validity of in silico approaches to predict in vivo effects2023
- Author(s)
  Kubota Akira、Hirano Masashi、Yoshinouchi Yuka、Chen Xing、Nakamura Michiko、Wakayama Yumi、Lee Jae Seung、Nakata Haruhiko、Iwata Hisato、Kawai Yusuke K.
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 269 Pages: 109619-109619
- DOI
  10.1016/j.cbpc.2023.109619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ0144, KAKENHI-PROJECT-23K25000, KAKENHI-PROJECT-23K27045
[Journal Article] ゼブラフィッシュを用いたネオニコチノイド系農薬の体内動態と発達神経毒性の解明2022
- Author(s)
  池本秀樹, 沖澤優花, 川合佑典, 一瀬貴大, 池中良徳, 久保田彰
- Journal Title
  
  環境ホルモン学会ニュースレター
  
  Volume: 24(4) Pages: 3-4
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Specific Gene Duplication and Loss of Cytochrome P450 in Families 1-3 in Carnivora (Mammalia, Laurasiatheria)2022
- Author(s)
  Kondo Mitsuki、Ikenaka Yoshinori、Nakayama Shouta M. M.、Kawai Yusuke K.、Ishizuka Mayumi
- Journal Title
  
  Animals
  
  Volume: 12 Issue: 20 Pages: 2821-2821
- DOI
  10.3390/ani12202821
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04919
[Journal Article] Toxicokinetic analysis of the anticoagulant rodenticides warfarin & diphacinone in Egyptian fruit bats (Rousettus aegyptiacus) as a comparative sensitivity assessment for Bonin fruit bats (Pteropus pselaphon)2022
- Author(s)
  Takeda Kazuki、Manago Kosuke、Morita Ayuko、Kawai Yusuke K.、Yasuo Nobuaki、Sekijima Masakazu、Ikenaka Yoshinori、Hashimoto Takuma、Minato Ryuichi、Oyamada Yusuke、Horikoshi Kazuo、Suzuki Hajime、Ishizuka Mayumi、Nakayama Shouta M.M.
- Journal Title
  
  Ecotoxicology and Environmental Safety
  
  Volume: 243 Pages: 113971-113971
- DOI
  10.1016/j.ecoenv.2022.113971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00620, KAKENHI-PROJECT-21H04919, KAKENHI-PROJECT-21K14988
[Journal Article] Duplication, Loss, and Evolutionary Features of Specific UDP-Glucuronosyltransferase Genes in Carnivora (Mammalia, Laurasiatheria)2022
- Author(s)
  Kondo Mitsuki、Ikenaka Yoshinori、Nakayama Shouta M. M.、Kawai Yusuke K.、Ishizuka Mayumi
- Journal Title
  
  Animals
  
  Volume: 12 Issue: 21 Pages: 2954-2954
- DOI
  10.3390/ani12212954
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04919
[Journal Article] Estrogenic and growth inhibitory responses to organophosphorus flame retardant metabolites in zebrafish embryos2022
- Author(s)
  Lee Jae Seung, Kawai K Yusuke, Morita Yuri, Covaci Adrian, Kubota Akira
- Journal Title
  
  Comparative Biochemistry and Physiology, Part C
  
  Volume: 256 Pages: 109321-109321
- DOI
  10.1016/j.cbpc.2022.109321
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Mechanistic investigation of developmental cardiovascular toxicity caused by organophosphate triesters and their metabolites in zebrafish embryo2022
- Author(s)
  Lee Jae Seung, Kawai K Yusuke, Morita Yuri, Covaci Adrian, Kubota Akira
- Journal Title
  
  環境ホルモン学会ニュースレター
  
  Volume: 24(3) Pages: 4-4
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Evolutionary history of mammalian UDP-glucuronosyltransferase (UGT)1 and UGT2 families: the emergence of UGT2B subfamily in eutherians after the diversification of flowering plants2021
- Author(s)
  View ORCID ProfileYusuke K. Kawai, Kasumi Sano, Yoshinori Ikenaka, Shouta M.M. Nakayama, Mitsuki Kondo, Akira Kubota, Mayumi Ishizuka
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.08.20.457063
- Open Access
- Data Source
  KAKENHI-PROJECT-21H04919
[Journal Article] Developmental circulatory failure caused by metabolites of organophosphorus flame retardants in zebrafish, Danio rerio2020
- Author(s)
  Jae Seung Lee, Yuri Morita, Yusuke K. Kawai, Adrian Covaci, Akira Kubota
- Journal Title
  
  Chemosphere
  
  Volume: 246 Pages: 125738-125738
- DOI
  10.1016/j.chemosphere.2019.125738
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Hepatic transcriptional profile and tissue distribution of cytochrome P450 1-3 genes in the red-crowned crane Grus japonensis2020
- Author(s)
  Kawai Yusuke K.、Itou Kiwamu、Yoshino Tomoo、Iima Hiroko、Matsumoto Fumio、Kubota Akira
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 228 Pages: 108643-108643
- DOI
  10.1016/j.cbpc.2019.108643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04275
[Journal Article] Characterization of function and genetic feature of UDP-glucuronosyltransferase in avian species2019
- Author(s)
  Kawai Yusuke K.、Shinya So、Ikenaka Yoshinori、Saengtienchai Aksorn、Kondo Takamitsu、Darwish Wageh Sobhy、Nakayama Shota M.M.、Mizukawa Hazuki、Ishizuka Mayumi
- Journal Title
  
  Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
  
  Volume: 217 Pages: 5-14
- DOI
  10.1016/j.cbpc.2018.11.001
- NAID
  120006803956
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20038, KAKENHI-PROJECT-18H04132
[Journal Article] Transcriptional profiling of cytochrome P450 genes in the liver of adult zebrafish, <i>Danio rerio</i>2019
- Author(s)
  Akira Kubota, Yusuke K. Kawai, Natsumi Yamashita, Jae Seung Lee, Daisuke Kondoh, Shuangyi Zhang, Yasunobu Nishi, Kazuyuki Suzuki, Takio Kitazawa, Hiroki Teraoka
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 44 Issue: 5 Pages: 347-356
- DOI
  10.2131/jts.44.347
- NAID
  130007642915
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05334, KAKENHI-PROJECT-19H04275
[Journal Article] Comparison of xenobiotic metabolism in phase I oxidation and phase II conjugation between rats and bird species2018
- Author(s)
  Saengtienchai A, Ikenaka Y, Kawata M, Kawai Y, Takeda K, Kondo T, Bortey-Sam N, Nakayama S.M.M, Mizukawa H, Ishizuka M.
- Journal Title
  
  CBP
  
  Volume: 214 Pages: 28-35
- DOI
  10.1016/j.cbpc.2018.08.007
- NAID
  120006769940
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19847, KAKENHI-PROJECT-16H01779, KAKENHI-PROJECT-18H04132, KAKENHI-PROJECT-17J05808, KAKENHI-PROJECT-17K20038
[Journal Article] Occurrence and seasonal variation of equine estrogens, equilin and equilenin, in the river water of Japan: Implication with endocrine-disrupting potentials to Japanese medaka (Oryzias latipes)2018
- Author(s)
  Ishibashi Hiroshi、Uchida Masaya、Yoshimoto Keisuke、Imamura Yuta、Yamamoto Ryoko、Ikenaka Yoshinori、Kawai Masahito、Ichikawa Nobuhiro、Takao Yuji、Tominaga Nobuaki、Ishibashi Yasuhiro、Arizono Koji
- Journal Title
  
  Environmental Pollution
  
  Volume: 239 Pages: 281-288
- DOI
  10.1016/j.envpol.2018.04.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04132, KAKENHI-PROJECT-17H01914
[Journal Article] The evolution of UDP-glycosyl/glucuronosyltransferase 1E (UGT1E) genes in bird lineages is linked to feeding habits but UGT2 genes is not.2018
- Author(s)
  Yusuke K. Kawai, Yoshinori Ikenaka, Mayumi Ishizuka, Akira Kubota
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 10 Pages: 1-13
- DOI
  10.1371/journal.pone.0205266
- NAID
  120006540774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-18H04132, KAKENHI-PROJECT-15H05334, KAKENHI-PROJECT-17K20038
[Journal Article] Comparison of xenobiotic metabolism in phase I oxidation and phase II conjugation between rats and bird species2018
- Author(s)
  Saengtienchai A, Ikenaka Y, Kawata M, Kawai Y, Takeda K, Kondo T, Bortey-Sam N, Nakayama S.M.M, Mizukawa H, Ishizuka M
- Journal Title
  
  Comparative Biochemistry & Physiology Part C
  
  Volume: in press
- NAID
  120006769940
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20038
[Journal Article] Uridine Diphosphate-Glucuronosyltransferase (UGT) 2B Subfamily Interspecies Differences in Carnivores2017
- Author(s)
  Kondo Takamitsu、Ikenaka Yoshinori、Nakayama Shouta M. M.、Kawai Yusuke K.、Mizukawa Hazuki、Mitani Yoko、Nomiyama Kei、Tanabe Shinsuke、Ishizuka Mayumi
- Journal Title
  
  Toxicological Sciences
  
  Volume: 158 Issue: 1 Pages: 90-100
- DOI
  10.1093/toxsci/kfx072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K20038, KAKENHI-PROJECT-26220103, KAKENHI-PROJECT-16H01779, KAKENHI-PROJECT-16H01784, KAKENHI-PROJECT-15H02825, KAKENHI-PROJECT-16H02989, KAKENHI-PROJECT-15K16132, KAKENHI-PROJECT-16K16197
[Presentation] Assessment of estrogenic effects of endocrine disrupting chemicals through estrogen receptors in animal models2024
- Author(s)
  Rehab YS. Ahmed, Dave Arthur Robledoc, Hisato Iwata, Masashi Hirano, Rumi Tanoue, Yusuke K. Kawai, Akira Kubota
- Organizer
  The 10th Copenhagen Workshop on Endocrine Disrupters
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo assessment and in silico prediction of estrogenic potency of endocrine disrupting chemicals using zebrafish (Danio rerio)2024
- Author(s)
  Akira Kubota, Masashi Hirano, Yuka Yoshinouchi, Hisato Iwata, Yusuke Kawai
- Organizer
  Pure and Applied Chemistry International Conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Assessment of estrogenic potency and the potential mode of action underlying single and binary exposure to estrogenic endocrine disrupting chemicals in zebrafish (Danio rerio)2024
- Author(s)
  Akira Kubota, Rehab YS. Ahmed, Rumi Tanoue, Masashi Hirano, Yusuke K. Kawai
- Organizer
  SOT 63rd Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo and in silico assessments of anti-androgenic and anti-estrogenic potentials of BPA and its analogs using zebrafish2023
- Author(s)
  Xing Chen, Masashi Hirano, Yusuke Kawai, Akira Kubota
- Organizer
  SETAC North America 44th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo and in silico assessment of estrogenic potency of endocrine disrupting chemicals using zebrafish (Danio rerio)2023
- Author(s)
  Akira Kubota, Masashi Hirano, Yuka Yoshinouchi, Hisato Iwata, Yusuke Kawai
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] ssessment of developmental toxicity and the mechanistic pathway underlying single and binary exposure to estrogenic endocrine disruptive chemicals in zebrafish2023
- Author(s)
  Ahmed, R., Kawai, Y.K., Tanoue, R. and Kubota, A.
- Organizer
  SOT 62nd Annual Meeting & ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Assessment of toxicokinetics and developmental neurotoxicity of neonicotinoid insecticides in zebrafish2023
- Author(s)
  Akira Kubota, Hideki Ikemoto, Yuka Okizawa, Kyoko Ogura, Nana Mizuhara, Rumi Tanoue, Kei Nomiyama, Yoshinori Ikenaka, Yusuke K. Kawai
- Organizer
  7th Chemical Hazard Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Phenotypic and transcriptomic effects of organophosphorus flame retardants and their metabolites in developing zebrafish2023
- Author(s)
  Jae Seung Lee, Yusuke Kawai, Yuri Morita, Adrian Covaci, Akira Kubota
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Developmental effects of 2,3,7,8-substituted and non-2,3,7,8-substituted polybrominated dibenzo-p-dioxins in zebrafish2023
- Author(s)
  Akira Kubota, Jae Seung Lee, Wataru Ishihara, Xing Chen, Akitoshi Goto, Tatsuya Kunisue, Yusuke Kawai
- Organizer
  The 43rd International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] In vivo and in silico assessment of antiandrogenic potentials for environmental chemicals using zebrafish2023
- Author(s)
  Chen, X., Hirano, M., Ishibashi, H., Lee, J.S., Kawai, Y.K. and Kubota, A.
- Organizer
  SOT 62nd Annual Meeting & ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Role of calcium signals in circulatory failure and spinal curvature caused by perfluorinated alkyl substances in developing zebrafish2022
- Author(s)
  Lee, J.S., Matsumoto, K., Kawai Y., Ishibashi, H. and Kubota, A.
- Organizer
  The 49th Annual Meeting of the Japanese Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Developmental effects of single and binary exposure to estrogenic endocrine disrupting chemicals on zebrafish2022
- Author(s)
  Ahmed, R., Kawai, Y.K. and Kubota, A.
- Organizer
  The 49th Annual Meeting of the Japanese Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Morphological and transcriptome analyses of perfluorinated alkyl substances in zebrafish embryos towards understanding of developmental toxicity and its mechanism2022
- Author(s)
  Lee, J.S., Matsumoto, K., Kawai Y., Ishibashi, H. and Kubota, A.
- Organizer
  Joint Conference on Environmental Chemicals
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] 食肉目Cytochrome P450 1-3 ファミリーの遺伝子重複・欠損による進化性状解明2022
- Author(s)
  近藤充希、池中良徳、中山翔太、川合佑典、石塚真由美
- Organizer
  内外環境応答・代謝酵素研究会
- Data Source
  KAKENHI-PROJECT-21H04919
[Presentation] Mechanistic investigation on distinct estrogenic and developmental responses to bisphenol analogues in zebrafish embryos2022
- Author(s)
  Chen, X., Lee, J.S., Kawai, Y.K., Kubota, A.
- Organizer
  The 49th Annual Meeting of the Japanese Society of Toxicology
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Avian interspecific differences in VKOR activity and inhibition: Insights from amino acid sequence and mRNA expression ratio of VKORC1 and VKORC1L1.2022
- Author(s)
  Ayuko Morita, Shouta M.M. Nakayama, Yoshinori Ikenaka, Yusuke K. Kawai, Yared B. Yohannes, Kohei Ogasawara, Yukiko Watanabe, Keisuke Saito, Kaoru Ueda, Mayumi Ishizuka
- Organizer
  15th International Conference of Asian Society of Conservation Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04919
[Presentation] Carnivora (Mammalia, Laurasiatheria) specific evolutional features and specific gene loss and duplication and in CYP450 1-3 families2022
- Author(s)
  近藤充希、池中良徳、中山翔太、川合佑典、石塚真由美
- Organizer
  第49回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-21H04919
[Presentation] In vivo and in silico assessment of anti-androgenic potentials for environmental chemicals using zebrafish2022
- Author(s)
  Chen, X., Hirano, M., Kawai, Y.K. and Kubota, A.
- Organizer
  Joint Conference on Environmental Chemicals
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Role of estrogen receptor in ameliorative effect of estrogen-like compounds on diethylstilbestrol-induced developmental toxicity in zebrafish embryos2022
- Author(s)
  Ahmed, R., Kawai, Y.K. and Kubota, A.
- Organizer
  Joint Conference on Environmental Chemicals
- Data Source
  KAKENHI-PROJECT-23K25000
[Presentation] Estrogenic potency and developmental toxicity of BPA and its alternatives in zebrafish embryos2022
- Author(s)
  Chen Xing, Kawai K Yusuke, Kubota Akira
- Organizer
  5th Chemical Hazard Symposium in Online
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] 鳥類における異物代謝遺伝子（シトクロムP450, グルクロン酸抱合酵素）の種差と進化2021
- Author(s)
  川合佑典
- Organizer
  第48回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15848
[Presentation] Assessment of developmental toxicity caused by organophosphate triesters and their metabolites using zebrafish2021
- Author(s)
  Kubota Akira, Lee Jae Seung, Kawai K Yusuke, Covaci Adrian
- Organizer
  The 9th International Congress of Asian Society of Toxicology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] ゼブラフィッシュを用いたリン酸エステル系難燃剤の代謝物の発生毒性評価2021
- Author(s)
  Jae Seung Lee, Yusuke K. Kawai, Yuri Morita, Adrian Covaci, Akira Kubota
- Organizer
  4th International Chemical Hazard Symposium & 第4回日本環境化学会北海道東北／中国四国／毒性部会合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] ゼブラフィッシュを用いたネオニコチノイド系農薬の体内動態と発達神経毒性の解明2021
- Author(s)
  池本秀樹, 沖澤優花, 川合佑典, 一瀬貴大, 池中良徳, 久保田彰
- Organizer
  第23回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Assessment of developmental toxicity caused by organophosphorus flame retardants and their metabolites in zebrafish embryos2021
- Author(s)
  Lee Jae Seung, Kawai K Yusuke, Morita Yuri, Covaci Adrian, Kubota Akira
- Organizer
  第23回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Counteracting effect of zearalenone on diethylstilbestrol-induced developmental toxicity in zebrafish2021
- Author(s)
  Salama Rehab, Kawai Yusuke, Kubota Akira
- Organizer
  第23回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] ゲノムデータベースを利用した脊椎動物がもつグルクロン酸抱合遺伝子の進化解析2021
- Author(s)
  川合佑典、池中良徳、中山翔太、久保田彰、石塚真由美
- Organizer
  第23回日本内分泌撹乱化学物質学会研究発表会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15848
[Presentation] Developmental toxicity of organophosphorus flame retardant metabolites in zebrafish embryos2021
- Author(s)
  Jae Seung Lee, Yuri Morita, Yusuke K. Kawai, Adrian Covaci, Akira Kubota
- Organizer
  日本環境毒性学会第1回オンライン研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Establishment of evaluation method for anti-androgenic potency of environmental chemicals using zebrafish2021
- Author(s)
  Chen Xing, Kawai K Yusuke, Hirano Masashi, Kubota Akira
- Organizer
  令和3年度日本環境毒性学会オンライン研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Characterization of Cytochrome P450 Genes and Enzymes in the Red-Crowned Cranes: Toward Understanding of Drug Sensitivity2020
- Author(s)
  Kubota Akira、Itou Kiwamu、Sakamoto Rikako、Yamamoto Shuhei、Yoshino Tomoo、Iima Hiroko、Matsumoto Fumio、Nishikawa Miu、Ikushiro Shin-ichi、Kawai Yusuke
- Organizer
  International Symposium on Chemical Hazards to Wildlife（Hokkaido University）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Developmental effects of organophosphorus flame retardants and their metabolites in zebrafish2019
- Author(s)
  Kubota Akira、Lee Jae Seung、Morita Yuri、Kawai Yusuke、Covaci Adrian
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] ゼブラフィッシュを用いたインビボおよびインシリコ解析によるビスフェノール類の内分泌撹乱作用の評価2019
- Author(s)
  久保田彰、平野将司、イゼスン、中村倫子、芳之内結加、岩田久人、川合佑典
- Organizer
  第25回日本環境毒性学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] 東京都小笠原諸島における殺鼠剤散布のアオウミガメへのリスク評価2019
- Author(s)
  山村快哉、武田一貴、中山翔太、川合佑典、森田鮎子、小松謙之、北山知代、近藤理美、池中良徳、石塚真由美
- Organizer
  第25回日本野生動物医学会大会（山口）
- Data Source
  KAKENHI-PROJECT-18H04132
[Presentation] タンチョウ（Grus japonensis）における異物代謝酵素シトクロム P450 1-3 遺伝子の同定・定量と機能解析2019
- Author(s)
  坂本梨果子、伊藤究、西川美宇、生城真一、吉野智生、飯間裕子、松本文雄、川合佑典、久保田彰
- Organizer
  第28回環境化学討論会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Developmental effects of organophosphorus flame retardants and their metabolites in zebrafish2019
- Author(s)
  Lee Jae Seung、Morita Yuri、Covaci Adrian、Kawai Yusuke、Kubota Akira
- Organizer
  28th Symposium on Environmental Chemistry
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] In vivo and in silico analyses of estrogenic potential of equine estrogens in zebrafish (Danio rerio)2019
- Author(s)
  Motomura Chika、Hirano Masashi、Ishibashi Hiroshi、Arizono Koji、Wakayama Yumi、Lee Jae Seung、Kawai Yusuke、Kubota Akira
- Organizer
  3rd International Chemical Hazard Symposium（Hokkaido University）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] Sensitivity of turtles to anticoagulant rodenticides: in vivo and in vitro sensitivity evaluation in green sea turtles (Chelonia mydas mydas) in the Ogasawara Islands2019
- Author(s)
  Shouta MM Nakayama, Yoshiya Yamamura, Kazuki Takeda, Yusuke Kawai, Ayuko Morita, Yoshinori Ikenaka, Noriyuki Komatsu, Chiho Kezuka, Mari Taniguchi, Chiyo Kitayama, Satomi Kondo, Mayumi Ishizuka
- Organizer
  International Symposium on Chemical Hazard in Wildlife
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04132
[Presentation] Evolution of Avian UDP-glucuronosyltransferase Genes in Relation to Feeding Habit2019
- Author(s)
  Kawai YK, Shinya S, Nakayama SMM, Ikenaka Y, Ishizuka M, Kubota A
- Organizer
  International Symposium on Chemical Hazard in Wildlife
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04132
[Presentation] ゼブラフィッシュ肝臓におけるシトクロムP450分子種のmRNA発現プロファイル2019
- Author(s)
  久保田彰、川合佑典、山下夏未、Lee Jae Seung、近藤大輔、Zhang Shuangyi 、西康暢、鈴木一由、北澤多喜雄、寺岡宏樹
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] 発達期ゼブラフィッシュにおけるリン酸エステル系難燃剤の代謝物の発生毒性2019
- Author(s)
  久保田彰、イゼスン、森田友理、Adrian Covaci 、川合佑典
- Organizer
  第22回環境ホルモン学会研究発表会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] ゼブラフィッシュを用いた新世代ビスフェノール類のエストロゲン様作用の比較2019
- Author(s)
  久保田彰、Lee Jae Seung、若山裕己、中村倫子、芳之内結加、岩田久人、平野将司、中田晴彦、川合佑典
- Organizer
  第46回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H04275
[Presentation] UDP-glucuronosyltransferase (UGT) 2B genetic feature and activities in Carnivores2017
- Author(s)
  "Takamitsu Kondo, Yoshinori Ikenaka, Shouta M.M. Nakayama, Yusuke K. Kawai, Hazuki Mizukawa, Yoko Mitani, Kei Nomyama, Shinsuke Tanabe, and Mayumi Ishizuka"
- Organizer
  9th International Toxicology Symposium in Nigeria
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20038
[Presentation] UDP-glucuronosyltransferase (UGT) among Pinnipedia and other carnivores2017
- Author(s)
  Takamitsu Kondo, Yoshinori Ikenaka, Shouta M.M. Nakayama, Yusuke K. Kawai, Hazuki Mizukawa, Yoko Mitani, Kei Nomiyama, Shinsuke Tanabe, and Mayumi Ishizuka
- Organizer
  the 19th International Symposium on Pollutant Responses in Marine Organisms (PRIMO 19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20038
[Presentation] Drug metabolism enzymes in Carnivora species2017
- Author(s)
  "Takamitsu Kondo, Yoshinori Ikenaka, Shouta M.M. Nakayama, Yusuke K. Kawai, Hazuki Mizukawa, Yoko Mitani, Kei Nomyama, Shinsuke Tanabe, and Mayumi Ishizuka"
- Organizer
  The 5th Sapporo Summer Seminar for One Health (SaSSOH)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20038

1. Kubota Akira (60432811)

# of Collaborated Projects: 5 results

# of Collaborated Products: 41 results
2. Ikenaka Yoshinori (40543509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. 石塚真由美 (50332474)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
4. 中山翔太 (90647629)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
5. 水川葉月 (60612661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 近藤大輔 (90708364)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 武田一貴 (00896350)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. Toyotome Takahito (90422245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木淳史 (30415195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 三谷曜子 (40538279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 星信彦 (10209223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小林篤史 (50431507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 有薗幸司 (70128148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 平野哲史 (70804590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 加藤恵介 (80276609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 宮原裕一 (80311330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 市川剛 (80438712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 岡松優子 (90527178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 江口哲史 (70595826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 早川卓志 (00758493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山崎淳平 (20732902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 北山知代 (00934275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 野見山桂 (30512686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 村田幸久 (40422365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 中村達朗 (80755554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 生城真一 (50244679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 田上瑠美 (60767226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. HIRANO Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. SEKIJIMA Masakazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 石橋弘志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. Chen Xing

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

Kawai Yusuke 川合 佑典

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The convergent evolution of metabolic systems in birds and mammals for adaptation to diversification of flowering plantsPrincipal Investigator

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[Journal Article] Evaluation of anticoagulant rodenticide sensitivity by examining in vivo and in vitro responses in avian species, focusing on raptors.2024

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[Journal Article] Assessment of developmental toxicity and the potential mode of action underlying single and binary exposure to estrogenic endocrine disrupting chemicals in zebrafish (Danio rerio)2024

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[Journal Article] fficient in vivo and in silico assessments of antiandrogenic potential in zebrafish2023

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[Journal Article] Characteristics of cytochrome P450-dependent metabolism against acetamiprid in the musk shrew (Suncus murinus)2023

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[Journal Article] In vivo and in silico assessments of estrogenic potencies of bisphenol A and its analogs in zebrafish (Danio rerio): Validity of in silico approaches to predict in vivo effects2023

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[Journal Article] ゼブラフィッシュを用いたネオニコチノイド系農薬の体内動態と発達神経毒性の解明2022

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[Journal Article] Specific Gene Duplication and Loss of Cytochrome P450 in Families 1-3 in Carnivora (Mammalia, Laurasiatheria)2022

Kawai Yusuke 川合佑典