Hiraoka Kei 平岡圭

Researcher Number	10719587
Other IDs
Affiliation (Current)	2025: 北海道大学, 医学研究院, 客員研究員
Affiliation (based on the past Project Information) *help	2017 – 2024: 北海道大学, 医学研究院, 客員研究員 2016: 北海道大学, 医学研究科, 客員研究員 2014 – 2015: 北海道大学, 医学(系)研究科(研究院), その他
Review Section/Research Field	Principal Investigator Basic Section 55040:Respiratory surgery-related / General surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Neurosurgery / General surgery
Keywords	Principal Investigator ウイルスベクター / 遺伝子治療 / プロドラッグ / レトロウイルス / 肺癌 / 膵癌 Except Principal Investigator 膵癌 / 膵癌新規治療 / DNAアプタマー / CA19-9 … More / K-RAS阻害治療 / 腫瘍選択的増殖型レトロウイルスベクター / 新規遺伝子治療 / レトロウイルス / 脳腫瘍 / ウイルスベクター / 放射線治療 / 遺伝子治療 / 膠芽腫 / 化学療法 / 実験外科学 / 外科 / 消化器外科 / 治療候補遺伝子 / バイオマーカー Less

新型コロナウイルス治療薬と化学療法を併用した膵癌新規治療法の開発
- Principal Investigator
  
  中村透
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
000
- Principal Investigator
  
  Nakamura Toru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
Retroviral replicating vector-mediated gene therapy for lung cancerPrincipal Investigator
- Principal Investigator
  
  Hiraoka Kei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Hokkaido University
Retroviral replicating vector mediated gene therapy activates anti-tumor immune responses in an immunocompetent pancreatic cancer model
- Principal Investigator
  
  Hirano Satoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
Discovering the biomarkers and development of new therapeutics in pancreatic cancer
- Principal Investigator
  
  Asano Toshimichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Development of prodrug activator gene therapy combined with radiation therapy in glioblastoma
- Principal Investigator
  
  Takahashi Masamichi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  National Cancer Center Japan
Retroviral Replicating Vector (RRV)- Mediated Prodrug-Activator Gene Therapy for Pancreatic CancerPrincipal Investigator
- Principal Investigator
  
  Hiraoka Kei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University

All 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Therapeutic activity of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer.2018
- Author(s)
  Inoko K, Hiraoka K, Inagaki A, Takahashi M, Kushibiki T, Hontani K, Takano H, Sato S, Takeuchi S, Nakamura T, Tsuchikawa T, Shichinohe T, Gruber HE, Jolly DJ, Kasahara N, Hirano S.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: epub ahead of print Issue: 7-8 Pages: 184-195
- DOI
  10.1038/s41417-018-0020-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10777
[Journal Article] Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model2017
- Author(s)
  Mitchell Leah A.、Lopez Espinoza Fernando、Mendoza Daniel、Kato Yuki、Inagaki Akihito、Hiraoka Kei、Kasahara Noriyuki、Gruber Harry E.、Jolly Douglas J.、Robbins Joan M.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 19 Issue: 7 Pages: 930-939
- DOI
  10.1093/neuonc/nox037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10777
[Journal Article] Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.2017
- Author(s)
  Hiraoka K, Inagaki A, Kato Y, Huang TT, Mitchell LA, Kamijima S, Takahashi M, Matsumoto H, Hacke K, Kruse CA, Ostertag D, Robbins JM, Gruber HE, Jolly DJ, Kasahara N
- Journal Title
  
  Neuro-Oncology
  
  Volume: 印刷中 Issue: 7 Pages: 918-929
- DOI
  10.1093/neuonc/nox038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06882, KAKENHI-PROJECT-16K10777
[Presentation] Retroviral replicating-vector mediated gene therapy activates anti-tumor immune responses in an immunocompetent pancreatic cancer model2020
- Author(s)
  丹羽弘貴、中村　透、櫛谷洋樹、猪子和穂、平岡　圭、稲垣亮仁、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08773
[Presentation] Therapeutic activity of prodrug activator gene therapy with Toca 511 in experimental models of lung cancer2020
- Author(s)
  櫛谷洋樹、平岡　圭、鈴木友啓、猪子和穂、稲垣亮仁、丹羽弘貴、佐々木勝則、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08773
[Presentation] プロドラッグ活性化遺伝子治療（Toca 511/5-FC治療）により誘導された抗腫瘍免疫応答の膵癌モデルに対する治療効果2020
- Author(s)
  Hiroki Niwa, Toru Nakamura, Hiroki Kushiya, Kazuho Inoko, Kei Hiraoka, Akihito Inagaki, Takahiro Tsuchikawa, Toshiaki Shichinohe, Douglas J Jolly, Noriyuki Kasahara, Satoshi Hirano
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02876
[Presentation] 膵癌に対するプロドラッグ活性化遺伝子治療（Toca 511/5-FC治療）で誘導された抗腫瘍免疫応答による腫瘍縮小効果2020
- Author(s)
  丹羽弘貴、中村　透、櫛谷洋樹、猪子和穂、土川貴裕、平岡　圭、七戸俊明、平野　聡
- Organizer
  第100回北海道医学大会腫瘍系分科会・第122回北海道癌談話会
- Data Source
  KAKENHI-PROJECT-18K08773
[Presentation] 膵癌に対するプロドラッグ活性化遺伝子治療（Toca 511/5-FC治療）で誘導された抗腫瘍免疫応答による腫瘍縮小効果2020
- Author(s)
  丹羽弘貴、中村透、櫛谷洋樹、猪子和穂、土川貴裕、平岡圭、七戸俊明、平野聡
- Organizer
  第100回北海道医学大会腫瘍系分科会・第122回北海道癌談話会
- Data Source
  KAKENHI-PROJECT-18H02876
[Presentation] Therapeutic efficacy of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer2016
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、高野博信、佐藤彰記、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  ASGCT 19th Annual Meeting
- Place of Presentation
  Marriott Wardman Park　（USA・Washington DC）
- Year and Date
  2016-05-04
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] Retroviral Replicating Vector-mediated Prodrug Activator Gene Therapy for Pancreatic Cancer2016
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  10th International Oncolytic Virus Meeting
- Place of Presentation
  Fairmont Waterfront　（Canada・Vancouver）
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] Prodrug activator gene therapy mediated by retroviral replicating vector (RRV) for pancreatic ductal adenocarcinoma2016
- Author(s)
  平岡　圭、猪子和穂、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第22回日本遺伝子細胞治療学会
- Place of Presentation
  虎ノ門ヒルズ　（東京都・港区）
- Year and Date
  2016-07-18
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] 増殖型レトロウイルスシステムを用いた膵癌に対するプロドラッグ活性化遺伝子治療2016
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、高野博信、佐藤彰記、中村　透、土川貴裕、七戸俊明、Harry E. Gruber、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場　（大阪府・大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] Retroviral replicating vector (RRV)-mediated prodrug activator gene therapy for pancreatic cancer2015
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高野博信、佐藤彰記、高橋瑞菜、中村　透、土川貴裕、七戸俊明、Harry E. Gruber、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場　（大阪府・大阪市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26461936

1. Nakamura Toru (70645796)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. Hirano Satoshi (50322813)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
3. 土川貴裕 (50507572)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. 七戸俊明 (70374353)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. Takahashi Masamichi (10436454)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. YANG JAY (60897619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Asano Toshimichi (10756688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 加賀基知三 (80224335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hiraoka Kei 平岡 圭

Research Projects

Research Products

Co-Researchers

新型コロナウイルス治療薬と化学療法を併用した膵癌新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

000

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Retroviral replicating vector-mediated gene therapy for lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Retroviral replicating vector mediated gene therapy activates anti-tumor immune responses in an immunocompetent pancreatic cancer model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovering the biomarkers and development of new therapeutics in pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of prodrug activator gene therapy combined with radiation therapy in glioblastoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Retroviral Replicating Vector (RRV)- Mediated Prodrug-Activator Gene Therapy for Pancreatic CancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Therapeutic activity of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Retroviral replicating-vector mediated gene therapy activates anti-tumor immune responses in an immunocompetent pancreatic cancer model2020

Author(s)

Organizer

Data Source

[Presentation] Therapeutic activity of prodrug activator gene therapy with Toca 511 in experimental models of lung cancer2020

Author(s)

Organizer

Data Source

[Presentation] プロドラッグ活性化遺伝子治療（Toca 511/5-FC治療）により誘導された抗腫瘍免疫応答の膵癌モデルに対する治療効果2020

Author(s)

Organizer

Data Source

[Presentation] 膵癌に対するプロドラッグ活性化遺伝子治療（Toca 511/5-FC治療）で誘導された抗腫瘍免疫応答による腫瘍縮小効果2020

Author(s)

Organizer

Data Source

[Presentation] 膵癌に対するプロドラッグ活性化遺伝子治療（Toca 511/5-FC治療）で誘導された抗腫瘍免疫応答による腫瘍縮小効果2020

Author(s)

Organizer

Hiraoka Kei 平岡圭