Nakamura Toru 中村透

… Alternative Names

Researcher Number	70645796
Other IDs
External Links
Affiliation (Current)	2021: 北海道大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help	2017 – 2021: 北海道大学, 医学研究院, 助教 2016: 北海道大学, 医学研究科, 助教 2012 – 2015: 北海道大学, 医学(系)研究科(研究院), 助教 2012: 北海道大学, 大学院・医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / General surgery Except Principal Investigator General surgery / Basic Section 55020:Digestive surgery-related / Digestive surgery / Basic Section 55040:Respiratory surgery-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator 膵癌 / 膵癌新規分子標的治療薬 / 膵癌バイオマーカー / 膵癌新規分子標的治療 / 細胞膜透過性ペプチド治療 / 分子標的治療 / 膵癌分子標的治療 / 細胞膜透過性ペプチド / C16orf74 / CA19-9 / DNAアプタマー … More Except Principal Investigator … More

CA19-9を標的とした共有結合DNAアプタマーによる膵癌新規治療法の開発Principal Investigator
- Principal Investigator
  
  中村透
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
Research on the mutual paracrine effect by MMP-9 and sCD154 between CD40 positive ESCC cells and platelets
- Principal Investigator
  
  佐々木勝則
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
ゲノム・遺伝子変異プロファイル解析を用いた膵癌における新規治療戦略の構築
- Principal Investigator
  
  浅野賢道
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
Development of retroviral replicating vector-mediated prodrug activator gene therapy for biliary tract cancer
- Principal Investigator
  
  岡村圭祐
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
膵癌の浸潤・増殖を阻害する細胞膜透過性ペプチドを応用した新規治療法の開発Principal Investigator
- Principal Investigator
  
  中村透
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
Retroviral replicating vector-mediated gene therapy for lung cancer
- Principal Investigator
  
  平岡圭
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Hokkaido University
Multi-omics analysis for hepato-biliary-pancreatic cancers
- Principal Investigator
  
  中川英刀
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Institute of Physical and Chemical Research
増殖型レトロウイルスを用いた遺伝子治療を応用した膵癌の新規治療戦略
- Principal Investigator
  
  平野聡
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hokkaido University
Development of immunotherapy following curative resection for refractory solid cancers
- Principal Investigator
  
  Tsuchikawa Takahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Discovering the biomarkers and development of new therapeutics in pancreatic cancer
- Principal Investigator
  
  Asano Toshimichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Near infrared fluorescence light imaging for para-aortic lymph node targeting in hepatobiliary malignancies
- Principal Investigator
  
  Noji Takehiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Treatment strategy to prevent postoperative recurrence of cancers by inducing host immune responses following neoadjuvant chemotherapy.
- Principal Investigator
  
  Tsuchikawa Takahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Retroviral Replicating Vector (RRV)- Mediated Prodrug-Activator Gene Therapy for Pancreatic Cancer
- Principal Investigator
  
  Hiraoka Kei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice
- Principal Investigator
  
  Hirano Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University
The cell permeable peptide inhibits pancreatic ductal adenocarcinoma cell proliferations and can be used as the molecular targeting druPrincipal Investigator
- Principal Investigator
  
  Nakamura Toru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
The analysis of the mechanism to induce the tumor specific immune responses by the anti-cancer agents and its clinical utilization
- Principal Investigator
  
  TSUCHIKAWA Takahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University
Identification of the marker for cholangiocarcinoma based on the data by proteomics and tissue microarray
- Principal Investigator
  
  HIRANO Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hokkaido University

All 2020 2019 2018 2017 2016 2015 2013

All Journal Article Presentation

[Journal Article] Role of Dimerized C16orf74 in Aggressive Pancreatic Cancer: A Novel Therapeutic Target2020
- Author(s)
  Kushibiki T, Nakamura T, Tsuda M, Tsuchikawa T, Hontani K, Inoko K, Takahashi M, Asano T, Okamura K, Murakami S, Kurashima Y, Ebihara Y, Noji T, Nakanishi Y, Tanaka K, Maishi N, Sasaki K, Park W-R, Shichinohe T, Hida K, Tanaka S, Hirano S.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 19 Pages: 187-198
- DOI
  10.1158/1535-7163.mct-19-0491
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07059, KAKENHI-PROJECT-18K08667, KAKENHI-PROJECT-18K09715
[Journal Article] 【がんにおけるPD-L1分子の発現調節】腫瘍局所環境における上皮間葉転換（EMT）とPD-L1の発現調節機構2019
- Author(s)
  1.土川貴裕，上野　峰，佐々木勝則，田中公貴，中西喜嗣，浅野賢道，野路武寛，中村　透，岡村圭祐，七戸俊明，平野　聡
- Journal Title
  
  癌と化学療法
  
  Volume: 46 Pages: 855-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10532
[Journal Article] Prognostic relevance of tertiary lymphoid organs following neoadjuvant chemoradiotherapy in pancreatic ductal adenocarcinoma2019
- Author(s)
  Kuwabara Shota、Tsuchikawa Takahiro、Nakamura Toru、Hatanaka Yutaka、Hatanaka Kanako C.、Sasaki Katsunori、Ono Masato、Umemoto Kazufumi、Suzuki Tomohiro、Sato Osamu、Hane Yuma、Nakanishi Yoshitsugu、Asano Toshimichi、Ebihara Yuma、Kurashima Yo、Noji Takehiro、Murakami Soichi、Okamura Keisuke et al.
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 1853-1862
- DOI
  10.1111/cas.14023
- NAID
  40021983711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10532
[Journal Article] Postoperative nutritional benefits of proximal parenchymal pancreatectomy for low-grade malignant lesions in the pancreatic head2019
- Author(s)
  Umemoto Kazufumi、Tsuchikawa Takahiro、Nakamura Toru、Okamura Keisuke、Noji Takehiro、Asano Toshimichi、Nakanishi Yoshitsugu、Tanaka Kimitaka、Hirano Satoshi
- Journal Title
  
  HPB
  
  Volume: 21 Pages: 1491-1496
- DOI
  10.1016/j.hpb.2019.03.359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10532
[Journal Article] 5-Aminolevulinic-acid-mediated Photodynamic Diagnosis Enhances the Detection of Peritoneal Metastases in Biliary Tract Cancer in Mice.2017
- Author(s)
  TOSHIHIRO KUSHIBIKI 1, TAKEHIRO NOJI 1, YUMA EBIHARA1, KOJI HONTANI 1, MASATO ONO1, SHOTA KUWABARA1, TORU NAKAMURA1, TAKAHIRO TSUCHIKAWA1, KEISUKE OKAMURA, MASAHIRO ISHIZUKA2 and SATOSHI HIRANO1
- Journal Title
  
  In vivo
  
  Volume: 31 Pages: 905-908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10044
[Journal Article] Stromal palladin expression is an independent prognostic factor in pancreatic ductal adenocarcinoma.2016
- Author(s)
  Sato D, Tsuchikawa T, Mitsuhashi T, Hatanaka Y, Marukawa K, Morooka A, Nakamura T, Shichinohe T, Matsuno Y, Hirano S
- Journal Title
  
  PLoS One
  
  Volume: 11
- DOI
  10.1371/journal.pone.0152523
- NAID
  120005757988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-25460449, KAKENHI-PROJECT-26461935, KAKENHI-PROJECT-16K08684
[Journal Article] Clinical impact of chemotherapy to improve tumor microenvironment of pancreatic cancer.2016
- Author(s)
  Tsuchikawa T, Takeuchi S, Nakamura T, Shichinohe T, Hirano S
- Journal Title
  
  World Journal of Gastrointestinal Oncology
  
  Volume: 8 Pages: 786-792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461935
[Journal Article] Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human.2015
- Author(s)
  Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S.
- Journal Title
  
  Cancer Res
  
  Volume: 75 Pages: 2629-40
- Data Source
  KAKENHI-PROJECT-26461935
[Journal Article] Inhibition of Eph receptor A4 by 2,5-dimethylpyrrolyl benzoic acid suppresses human pancreatic cancer growing orthotopically in nude mice.2015
- Author(s)
  Takano H, Nakamura T, Tsuchikawa T, Kushibiki T, Hontani K, Inoko K, Takahashi M, Sato S, Abe H, Takeuchi S, Sato N, Hiraoka K, Nishihara H, Shichinohe T, Hirano S.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 41063-76
- DOI
  10.18632/oncotarget.5729
- NAID
  120005697203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462052
[Journal Article] Novel aspects of preoperative chemo(radiation)therapy improving anti-tumor immunity in pancreatic cancer.2013
- Author(s)
  Tsuchikawa T, Hirano S, Tanaka E, Matsumoto J, Kato K, Nakamura T, Ebihara Y, Shichinohe T.
- Journal Title
  
  Cancer Sci
  
  Volume: 104(5) Pages: 531-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659632
[Presentation] Thymidine Kinase-1 is potential target for tumor marker and therapy of pancreatic cancer.2018
- Author(s)
  Nakamura T
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10447
[Presentation] Therapeutic efficacy of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer2016
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、高野博信、佐藤彰記、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  ASGCT 19th Annual Meeting
- Place of Presentation
  Marriott Wardman Park　（USA・Washington DC）
- Year and Date
  2016-05-04
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] 膵癌局所免疫環境に着目した新規免疫療法の開発2016
- Author(s)
  土川貴裕，武内慎太郎，田中公貴，中西喜嗣，浅野賢道，野路武寛，中村　透，岡村圭祐，七戸俊明，平野　聡
- Organizer
  第７１回消化器外科学会
- Place of Presentation
  あわぎんホール、アスティ徳島（徳島県徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26461935
[Presentation] 膵癌化学療法抵抗性のメカニズム解析とMDSCに着目した新規免疫療法の開発2016
- Author(s)
  土川貴裕，武内慎太郎，中村　透，七戸俊明，平野　聡
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-26461935
[Presentation] Prodrug activator gene therapy mediated by retroviral replicating vector (RRV) for pancreatic ductal adenocarcinoma2016
- Author(s)
  平岡　圭、猪子和穂、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第22回日本遺伝子細胞治療学会
- Place of Presentation
  虎ノ門ヒルズ　（東京都・港区）
- Year and Date
  2016-07-18
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] 増殖型レトロウイルスシステムを用いた膵癌に対するプロドラッグ活性化遺伝子治療2016
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、高野博信、佐藤彰記、中村　透、土川貴裕、七戸俊明、Harry E. Gruber、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場　（大阪府・大阪市）
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] Retroviral Replicating Vector-mediated Prodrug Activator Gene Therapy for Pancreatic Cancer2016
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高橋瑞奈、櫛引敏寛、本谷康二、中村　透、土川貴裕、七戸俊明、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  10th International Oncolytic Virus Meeting
- Place of Presentation
  Fairmont Waterfront　（Canada・Vancouver）
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-26461936
[Presentation] Retroviral replicating vector (RRV)-mediated prodrug activator gene therapy for pancreatic cancer2015
- Author(s)
  猪子和穂、平岡　圭、稲垣亮仁、高野博信、佐藤彰記、高橋瑞菜、中村　透、土川貴裕、七戸俊明、Harry E. Gruber、Douglas J. Jolly、Noriyuki Kasahara、平野　聡
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場　（大阪府・大阪市）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26461936

1. HIRANO Satoshi (50322813)

# of Collaborated Projects: 16 results

# of Collaborated Products: 15 results
2. TSUCHIKAWA Takahiro (50507572)

# of Collaborated Projects: 14 results

# of Collaborated Products: 16 results
3. 七戸俊明 (70374353)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
4. Hiraoka Kei (10719587)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
5. Asano Toshimichi (10756688)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. 宮本正樹 (40333611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 岡村圭祐 (90724401)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 佐々木勝則 (60336394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TANAKA EIICHI (60374279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Noji Takehiro (10739296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 近藤哲 (30215454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高橋雅道 (10436454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 加賀基知三 (80224335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中川英刀 (50361621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 井元清哉 (10345027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 山上裕機 (20191190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 相方浩 (30403512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 二階堂愛 (00383290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 畑中豊 (30589924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 畑中佳奈子 (10399834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 天野虎次 (20374514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YANG JAY (60897619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. HIDA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. HIDA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. MAISHI Nako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 松野吉宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 三橋智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 田中伸哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 津田真寿美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Toru 中村 透

NAKAMURA Toru 中村 透

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CA19-9を標的とした共有結合DNAアプタマーによる膵癌新規治療法の開発Principal Investigator

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膵癌の浸潤・増殖を阻害する細胞膜透過性ペプチドを応用した新規治療法の開発Principal Investigator

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The cell permeable peptide inhibits pancreatic ductal adenocarcinoma cell proliferations and can be used as the molecular targeting druPrincipal Investigator

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Nakamura Toru 中村透

NAKAMURA Toru 中村透