Ohka Fumiharu 大岡史治

Researcher Number	10725724
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 名古屋大学, 医学系研究科, 講師 2016 – 2019: 名古屋大学, 医学系研究科, 助教 2015: 名古屋大学, 医学部附属病院, 病院助教 2014: 名古屋大学, 医学(系)研究科(研究院), 特別研究員(PD)
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator エピゲノム異常 / 悪性脳腫瘍 / 脳腫瘍学 / EZH2 / 神経膠腫 / オルガノイドモデル / ゲノム異常 / 脳腫瘍オルガノイドモデル / 脳腫瘍のエピゲノム異常 / 異常エンハンサー … More / スーパーエンハンサー異常 / スーパーエンハンサー / Epigenetic alteration / Glioma mouse model / Brain tumor / エピゲノム治療 / 悪性神経膠腫 / 脳腫瘍マウスモデルの樹立 … More Except Principal Investigator 脳腫瘍 / シングルセル解析 / リアルタイムPCR / エクソソーム / 下垂体腫瘍 / 異所性リンパ組織 / 腫瘍微小環境 / 腫瘍免疫 / 髄膜腫 / 蛋白発現解析 / もやもや病 / 網羅的遺伝子発現解析 / 病変部血管 / 次世代シークエンシング / 小児もやもや病 / シングルセル / CRISPR/Cas9ノックアウト / DNAバーコードラベル / 神経膠腫 / CRISPR/Cas9 / 進化トラジェクション / 遺伝子診断 / ゲノム / 尿遺伝子解析 / 数理モデル / 悪性脳腫瘍 / エピゲノム異常 / 染色体構造異常 / マウスモデル / ポドプラニン / キメラ抗原受容体T細胞 / 細胞免疫療法 / ネオアンチゲン / 神経幹細胞 / ハイブリッドベクター / エピゲノム制御 / 脊髄損傷 / 脱分化 / 上位細胞 / アフリカツメガエル / 歯髄幹細胞 / 神経再生 / 内在性神経幹細胞 / グリア瘢痕 / ウイルスベクター / 上衣細胞 / Neurod4 / 神経転写因子 Less

難治性髄膜腫におけるがん免疫微小環境の解明
- Principal Investigator
  
  伊藤英治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Aichi Medical University
オルガノイドモデルを用いた脳腫瘍の悪性転化を誘導する分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  大岡史治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
New molecular diagnostic technique for pituitary neuroendocrine tumors
- Principal Investigator
  
  竹内和人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
もやもや病脳動脈COL15A1発現低下のエピゲノム制御機構と病態生理の解明
- Principal Investigator
  
  荒木芳生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
The evolutional trajection and precision-medicine to gliomas
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury
- Principal Investigator
  
  Nishimura Yusuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Aberrant chromatin remodeling induced by super-enhancer formation in malignant gliomaPrincipal Investigator
- Principal Investigator
  
  Ohka Fumiharu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formation
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
Remodeling of altered epigenetic regulation via targeting epigenetic factor during glioma formationPrincipal Investigator
- Principal Investigator
  
  Ohka Fumiharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Nagoya University
Identification of a novel epigenetic modifier in gliomagenesisPrincipal Investigator
- Principal Investigator
  
  Ohka Fumiharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Nagoya University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Other

[Journal Article] All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an <i>ex Vivo</i> Brain Tumor Model2023
- Author(s)
  Chattrairat Kunanon、Yasui Takao、Suzuki Shunsuke、Natsume Atsushi、Nagashima Kazuki、Iida Mikiko、Zhang Min、Shimada Taisuke、Kato Akira、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Yanagida Takeshi、Baba Yoshinobu
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 3 Pages: 2235-2244
- DOI
  10.1021/acsnano.2c08526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05778, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-21H01968
[Journal Article] Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy2023
- Author(s)
  Takahashi Hiromi、Yasui Takao、Hirano Masaki、Shinjo Keiko、Miyazaki Yusuke、Shinoda Wataru、Hasegawa Takeshi、Natsume Atsushi、Kitano Yotaro、Ida Mikiko、Zhang Min、Shimada Taisuke、Paisrisarn Piyawan、Zhu Zetao、Ohka Fumiharu、Aoki Kosuke、Rahong Sakon、Nagashima Kazuki、Yanagida Takeshi、Baba Yoshinobu
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 234 Pages: 115318-115318
- DOI
  10.1016/j.bios.2023.115318
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0209, KAKENHI-PROJECT-19K07661, KAKENHI-PROJECT-23K06633, KAKENHI-PROJECT-21K18979, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-21H01968
[Journal Article] Easy-to-use machine learning system for the prediction of IDH mutation and 1p/19q codeletion using MRI images of adult-type diffuse gliomas2023
- Author(s)
  Nishikawa Tomohide、Ohka Fumiharu、Aoki Kosuke、Suzuki Hiromichi、Motomura Kazuya、Yamaguchi Junya、Maeda Sachi、Kibe Yuji、Shimizu Hiroki、Natsume Atsushi、Innan Hideki、Saito Ryuta
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 40 Issue: 2 Pages: 85-92
- DOI
  10.1007/s10014-023-00459-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19591, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-23K24449
[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021
- Author(s)
  Kitano Yotaro、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Motomura Kazuya、Tanahashi Kuniaki、Hirano Masaki、Naganawa Tsuyoshi、Iida Mikiko、Shiraki Yukihiro、Nishikawa Tomohide、Shimizu Hiroyuki、Yamaguchi Junya、Maeda Sachi、Suzuki Hidenori、Wakabayashi Toshihiko、Baba Yoshinobu、Yasui Takao、Natsume Atsushi
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13 Issue: 15 Pages: 17316-17329
- DOI
  10.1021/acsami.1c01754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21124, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-19KK0228
[Journal Article] Newly established patient-derived organoid model of intracranial meningioma2021
- Author(s)
  Yamazaki Shintaro、Ohka Fumiharu、Hirano Masaki、Shiraki Yukihiro、Motomura Kazuya et al
- Journal Title
  
  Neuro-Oncology
  
  Volume: 23 Issue: 11 Pages: 1936-1948
- DOI
  10.1093/neuonc/noab155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-21K16645, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-20H03511, KAKENHI-PROJECT-20J01889, KAKENHI-PROJECT-20K20598
[Journal Article] Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury2021
- Author(s)
  Fukuoka Toshiki、Kato Akira、Hirano Masaki、Ohka Fumiharu、Aoki Kosuke、Awaya Takayuki、Adilijiang Alimu、Sachi Maeda、Tanahashi Kuniaki、Yamaguchi Junya、Motomura Kazuya、Shimizu Hiroyuki、Nagashima Yoshitaka、Ando Ryo、Wakabayashi Toshihiko、Lee-Liu Dasfne、Larrain Juan、Nishimura Yusuke、Natsume Atsushi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 2 Pages: 102074-102074
- DOI
  10.1016/j.isci.2021.102074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-19K09453
[Journal Article] H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant.2020
- Author(s)
  Maeda S, Ohka F, Okuno Y, Aoki K, Motomura K, Takeuchi K, Kusakari H, Yanagisawa N, Sato S, Yamaguchi J, Tanahashi K, Hirano M, Kato A, Shimizu H, Kitano Y, Yamazaki S, Yamashita S, Takeshima H, Shinjo K, Kondo Y, Wakabayashi T, Natsume A.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 8 Issue: 1 Pages: 8-19
- DOI
  10.1186/s40478-020-0882-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09478, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17K16643, KAKENHI-PROJECT-17K17792, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-20K20598
[Journal Article] Trautmann-focused mastoidectomy for a simple, safe presigmoid approach: technical note.2020
- Author(s)
  Tanahashi K, Uda K, Araki Y, Takeuchi K, Choo J, Chalise L, Motomura K, Ohka F, Wakabayashi T, Natsume A.
- Journal Title
  
  J Neurosurg.
  
  Volume: 3 Issue: 3 Pages: 1-5
- DOI
  10.3171/2020.1.jns193179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-17K16639, KAKENHI-PROJECT-17K10862
[Journal Article] Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas2019
- Author(s)
  Ohka Fumiharu、Shinjo Keiko、Deguchi Shoichi、Matsui Yusuke et al.
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 19 Pages: 4814-4827
- DOI
  10.1158/0008-5472.can-19-1272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18151, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04899, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-17K07247
[Journal Article] Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping.2019
- Author(s)
  Motomura K, Chalise L, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Yamaguchi J, Shimizu H, Wakabayashi T, Natsume A.
- Journal Title
  
  J Neurosurg.
  
  Volume: 17 Issue: 6 Pages: 1-9
- DOI
  10.3171/2019.3.jns19211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18H02911
[Presentation] Epigenetic Consequences of Genetic Alterations in Cell of Origin for Glioma2022
- Author(s)
  大岡史治
- Organizer
  2022 SNO Annual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09478
[Presentation] 診断困難な成人diffuse midline glioma, H3 K27M-mutantにおけるddPCRの有用性2019
- Author(s)
  前田紗知、大岡史治、平野雅規、青木恒介、竹内和人、本村和也、棚橋邦明、加藤彰、北野詳太郎、西川知秀、清水浩之、山口純矢、山﨑慎太郎、若林俊彦、夏目敦至
- Organizer
  第20回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-19K09478
[Presentation] マウスモデルを用いたIDH野生型グレードIIIグリオーマ形成に寄与するエピゲノム異常の解析2018
- Author(s)
  大岡史治、出口彰一、鈴木啓道、青木恒介、加藤　彰、山道　茜、勝島啓佑、新城恵子、若林俊彦、近藤豊、夏目敦至
- Organizer
  第19回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] Epigenetic treatment for IDH-wildtype lower grade glioma, targeting dysregulation of EZH2-H3K27me32017
- Author(s)
  Fumiharu Ohka, Atsushi Natsume, Hiromichi Suzuki, Shoichi Deguchi, Keisuke Katsushima, Keiko Shinjo, Toshihiko Wakabayashi, Yutaka Kondo
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] IDH野生型グレードIIIグリオーマ形成におけるエピゲノムリプログラミング2017
- Author(s)
  大岡史治、出口彰一、山道茜、鈴木啓道、青木恒介、加藤　彰、勝島啓佑、新城恵子、若林俊彦、近藤豊、夏目敦至
- Organizer
  第35回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] Epigenetic treatment strategy for IDH-wildtype grade III glioma2017
- Author(s)
  Fumiharu Ohka, Shoichi Deguchi, Hiromichi Suzuki, Kosuke Aoki, Keisuke Katsushima, Keiko Shinjo, Toshihiko Wakabayashi, Yutaka Kondo, Atsushi Natsume  
- Organizer
  日本脳神経外科学会第76回学術総会
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] Epigenomic treatment for IDH wild-type grade III glioma, targeting dysregulation of EZH2-H3K27me32016
- Author(s)
  Fumiharu Ohka, Atsushi Natsume, Hiromichi Suzuki, Kosuke Aoki, Shoichi Deguchi, Keisuke Katsushima, Keiko Shinjo, Toshihiko Wakabayashi, Yutaka Kondo
- Organizer
  2016 SNO annual meeting
- Place of Presentation
  米国アリゾナ州スコッツデール
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861172
[Presentation] Epigenomic treatment for IDH wild-type grade III glioma, targeting dysregulation of EZH2-H3K27me32016
- Author(s)
  Fumiharu Ohka, Atsushi Natsume, Hiromichi Suzuki, Kosuke Aoki, Shoichi Deguchi, Keisuke Katsushima, Keiko Shinjo, Toshihiko Wakabayashi, Yutaka Kondo
- Organizer
  2016 SNO annual meeting
- Place of Presentation
  Scottsdale (USA)
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] IDH野生型グレード3グリオーマに対する新規エピジェネティクス治療の開発2016
- Author(s)
  大岡史治, 出口彰一, 鈴木啓道, 青木恒介, 加藤　彰,勝島啓佑, 新城恵子, 若林俊彦, 近藤豊, 夏目敦至
- Organizer
  第34回日本脳腫瘍学会学術集会
- Place of Presentation
  甲府富士屋ホテル（山梨県甲府市）
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] IDH野生型グレード3グリオーマ形成に寄与するエピゲノム異常を標的とした新規治療2016
- Author(s)
  大岡史治, 出口彰一, 鈴木啓道, 青木恒介, 加藤　彰,勝島啓佑, 新城恵子, 若林俊彦, 近藤豊, 夏目敦至
- Organizer
  日本脳神経外科学会第75回学術総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] EZH2を標的としたIDH1野生型グリオーマの新規治療戦略2016
- Author(s)
  大岡史治, 夏目敦至, 鈴木啓道, 出口彰一,勝島啓佑, 新城恵子, 若林俊彦, 近藤豊
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K20003
[Presentation] クロマチンダイナミクスを誘導するEZH2を標的とした膠芽腫の新規治療戦略2015
- Author(s)
  大岡史治　出口彰一　鈴木啓道　勝島啓佑　新城恵子若林俊彦　近藤豊　夏目敦至
- Organizer
  日本脳神経外科学会第74回学術総会
- Place of Presentation
  北海道札幌市　ロイトン札幌
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-26861172
[Presentation] エピゲノム異常を誘導するEZH2を標的としたProneural GBMに対する新規治療戦略2015
- Author(s)
  大岡史治　出口彰一　鈴木啓道　勝島啓佑　新城恵子若林俊彦　近藤豊　夏目敦至
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  京都府京都市　グランドプリンスホテル京都
- Year and Date
  2015-12-07
- Data Source
  KAKENHI-PROJECT-26861172
[Presentation] Role of Dysregulation of EZH2-H3K27me3 in Gliomagenesis2015
- Author(s)
  大岡史治　夏目敦至　出口彰一　勝島啓佑　新城恵子　若林俊彦　近藤豊
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市　名古屋国際会議場
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26861172
[Presentation] GBM形成に重要な役割を果たすエピゲノム異常の蓄積
- Author(s)
  大岡史治
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-26861172
[Presentation] 膠芽腫の悪性転化に関わるエピゲノム異常を標的とした新規治療戦略の検討
- Author(s)
  大岡史治
- Organizer
  日本脳神経外科学会第73回学術総会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-26861172
[Presentation] 二次性膠芽腫マウスにおける経時的なクロマチンリモデリングによるエピゲノム変化
- Author(s)
  大岡史治
- Organizer
  第32回日本脳腫瘍学会学術集会
- Place of Presentation
  シェラトン・グランデ・トーキョーベイホテル（千葉県浦安市）
- Year and Date
  2014-12-07 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26861172
[]

1. Natsume Atsushi (30362255)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. 青木恒介 (10759773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Nishimura Yusuke (20447816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 平野雅規 (40823076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 加藤彰 (50793056)

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6. 日野原邦彦 (50549467)

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7. 荒木芳生 (80467290)

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8. 金森史哲 (00905979)

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9. 横山欣也 (90867904)

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10. 伊藤英治 (30402605)

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11. 大野真佐輔 (40402606)

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12. 藤田貢 (40609997)

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13. 倉光俊一郎 (90972844)

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14. 山下公大 (80535427)

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15. 本村和也 (30467295)

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16. 竹内和人 (90710088)

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17. 永田雄一 (20834659)

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18. YASUI Takao

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19. 新城恵子

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20. 松井佑介

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21. 鈴木啓道

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Ohka Fumiharu 大岡 史治

Research Projects

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難治性髄膜腫におけるがん免疫微小環境の解明

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オルガノイドモデルを用いた脳腫瘍の悪性転化を誘導する分子メカニズムの解明Principal Investigator

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New molecular diagnostic technique for pituitary neuroendocrine tumors

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もやもや病脳動脈COL15A1発現低下のエピゲノム制御機構と病態生理の解明

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The evolutional trajection and precision-medicine to gliomas

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Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury

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Aberrant chromatin remodeling induced by super-enhancer formation in malignant gliomaPrincipal Investigator

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Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formation

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Remodeling of altered epigenetic regulation via targeting epigenetic factor during glioma formationPrincipal Investigator

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Identification of a novel epigenetic modifier in gliomagenesisPrincipal Investigator

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[Journal Article] All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an <i>ex Vivo</i> Brain Tumor Model2023

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[Journal Article] Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy2023

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[Journal Article] Easy-to-use machine learning system for the prediction of IDH mutation and 1p/19q codeletion using MRI images of adult-type diffuse gliomas2023

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[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021

Ohka Fumiharu 大岡史治