YONEYAMA YOSUKE 米山鷹介

… Alternative Names

Yoneyama Yosuke 米山鷹介

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Researcher Number	10748289
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 講師 2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院医学系研究科, 講師 2019 – 2024: 東京医科歯科大学, 統合研究機構, 助教 2016: 東京大学, 大学院農学生命科学研究科(農学部), 特任研究員 2015: 東京大学, 農学生命科学研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Animal production science Except Principal Investigator Basic Section 42030:Animal life science-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator オルガノイド / バイオマーカー / 肝線維化 / NASH / 脂肪肝炎 / 線維化 / 細胞間シグナル / ヒトiPS細胞 / 脂肪性肝炎 / アセチル化 / インスリン受容体基質 / インスリン様成長因子 … More Except Principal Investigator … More 細胞内情報伝達経路 / 糖代謝 / アミノ酸シグナル / アミノ酸 / 選択的スプライシング / 糖脂質代謝 / オルニチンシグナル / 代謝制御性アミノ酸シグナル / 脂質代謝 / オルニチン / エネルギー分配 / オルガノイド / 副呼吸 / 腸呼吸 Less

オルガノイドを活用した活動性MASHの発症機構の解明と予防・治療戦略の開発Principal Investigator
- Principal Investigator
  
  米山鷹介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  The University of Osaka
オルガノイドから導出された早期肝線維化バイオマーカーに基づくヒトNASH病態解析Principal Investigator
- Principal Investigator
  
  米山鷹介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
生体の糖脂質代謝スイッチを誘導するオルニチン情報伝達経路の同定とその制御
- Principal Investigator
  
  伯野史彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  The University of Tokyo
哺乳類腸呼吸メカニズムの理解と制御
- Principal Investigator
  
  武部貴則
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Tokyo Medical and Dental University
Mechanism of intercellular signaling in steatohepatitis using human liver organoidsPrincipal Investigator
- Principal Investigator
  
  Yoneyama Yosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanisms for proliferation-differentiation switch of skeletal muscle stem cells in response to metabolic signalingPrincipal Investigator
- Principal Investigator
  
  Yoneyama Yosuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Animal production science
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation Book Patent

[Book] オルガノイドがもたらすライフサイエンス革命「オルガノイドの移植とライブイメージング」2024
- Author(s)
  米山鷹介，佐伯憲和
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22K06923
[Book] 肝不全・肝硬変に対する再生療法－最先端の今　「オルガノイド研究の最先端」2021
- Author(s)
  米山鷹介，武部貴則
- Total Pages
  8
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-19K16536
[Book] 腸呼吸技術（EVA法）を用いたCOVID-19関連重症呼吸器合併症治療の可能性2021
- Author(s)
  岡部亮、米山鷹介、武部貴則
- Total Pages
  8
- Publisher
  科学論評社
- Data Source
  KAKENHI-PROJECT-19K16536
[Book] ヒト内胚葉オルガノイド研究の最新動向2021
- Author(s)
  米山鷹介
- Total Pages
  7
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19K16536
[Book] 臨床応用をめざすヒューマンオルガノイド研究2020
- Author(s)
  高山真秀、米山鷹介、武部貴則
- Total Pages
  7
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19K16536
[Journal Article] Advanced Interferometry with 3-D Structured Illumination Reveals the Surface Fine Structure of Complex Biospecimens2024
- Author(s)
  Takahisa Matsuzaki, Ryuzo Kawamura, Akihisa Yamamoto, Hozumi Takahashi, Mai Fujii, Shodai Togo, Yosuke Yoneyama, Fumihiko Hakuno, Shin-Ichiro Takahashi, Masami Suganuma, Seiichiro Nakabayashi, Shivani Sharma, James K. Gimzewski, Hiroshi Y. Yoshikawa
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 15 Issue: 4 Pages: 1097-1104
- DOI
  10.1021/acs.jpclett.3c02767
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18576, KAKENHI-PROJECT-22KJ2214, KAKENHI-PROJECT-19KK0128, KAKENHI-PROJECT-22K06923, KAKENHI-PUBLICLY-22H05423, KAKENHI-PROJECT-22H00302
[Journal Article] Quality Control of Stem Cell-Based Cultured Meat According to Specific Differentiation Abilities2024
- Author(s)
  Naraoka Yuna、Mabuchi Yo、Kiuchi Mai、Kumagai Kyoko、Hisamatsu Daisuke、Yoneyama Yosuke、Takebe Takanori、Akazawa Chihiro
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 2 Pages: 135-135
- DOI
  10.3390/cells13020135
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-21H03328
[Journal Article] Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines2024
- Author(s)
  Ogasawara N, Kano Y, Yoneyama Y, Kobayashi S, Watanabe S, Kirino S, Velez-Bravo FD, Hong Y, Ostapiuk A, Lutsik P, Onishi I, Yamauchi S, Hiraguri Y, Ito G, Kinugasa Y, Ohashi K, Watanabe M, Okamoto R, Tejpar S, Yui S.
- Journal Title
  
  iScience
  
  Volume: 27 Issue: 3 Pages: 109247-109247
- DOI
  10.1016/j.isci.2024.109247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K09680, KAKENHI-PROJECT-23K07394, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-23K27578
[Journal Article] Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-192023
- Author(s)
  Kawakami E,Saiki N,Yoneyama Y,Moriya C,Maezawa M,Kawamura S,Kinebuchi A,Kono T,Funata M,Sakoda A,Kondo S,Ebihara T,Matsumoto H,Togami Y,Ogura H,Sugihara F,Okuzaki D,Kojima T,Deguchi S,Vallee S,McQuade S,Islam R,Natarajan M,Ishigaki H,Nakayama M,Nguyen CT,Kitagawa Y,Wu Y,Mori K,Hishiki T, ... Takebe T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 30 Issue: 10 Pages: 1315-1330.e10
- DOI
  10.1016/j.stem.2023.09.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07532, KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-23K07921, KAKENHI-PROJECT-23K27671
[Journal Article] Preparation of mechanically patterned hydrogels for controlling the self-condensation of cells2023
- Author(s)
  Matsuzaki Takahisa, Kawano Yuma, Horikiri Momoka, Shimokawa Yuko, Yamazaki Takashi, Okuma Nao, Koike Hiroyuki, Kimura Masaki, Kawamura Ryuzo, Yoneyama Yosuke, Furuichi Yasuro, Hakuno Fumihiko, Takahashi Shin-Ichiro, Nakabayashi Seiichiro, Okamoto Satoshi, Nakauchi Hiromitsu, Taniguchi Hideki, Takebe Takanori, et al
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 3 Pages: 102471-102471
- DOI
  10.1016/j.xpro.2023.102471
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19924, KAKENHI-PROJECT-23K18576, KAKENHI-PROJECT-22K06923, KAKENHI-PUBLICLY-22H05423, KAKENHI-PROJECT-22H00302, KAKENHI-PROJECT-20H04079
[Journal Article] Enteral liquid ventilation oxygenates a hypoxic pig model2023
- Author(s)
  Tasuku Fujii,Yosuke Yoneyama,Akiko Kinebuchi,Hiroshi Date,Kimitoshi Nishiwaki,Takanori Takebe
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 3 Pages: 106142-106142
- DOI
  10.1016/j.isci.2023.106142
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09045, KAKENHI-PROJECT-21H04822
[Journal Article] En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH2022
- Author(s)
  Kimura Masaki、Iguchi Takuma、Iwasawa Kentaro、Dunn Andrew、Thompson Wendy L.、Yoneyama Yosuke、...、Takebe Takanori
- Journal Title
  
  Cell
  
  Volume: 185 Issue: 22 Pages: 4216-4232.e16
- DOI
  10.1016/j.cell.2022.09.031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-21H04822
[Journal Article] NADPH-Oxidase Derived Hydrogen Peroxide and Irs2b Facilitate Re-oxygenation-Induced Catch-Up Growth in Zebrafish Embryo2022
- Author(s)
  Zasu Ayaka、Hishima Futa、Thauvin Marion、Yoneyama Yosuke、Kitani Yoichiro、Hakuno Fumihiko、Volovitch Michel、Takahashi Shin-Ichiro、Vriz Sophie、Rampon Christine、Kamei Hiroyasu
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 13
- DOI
  10.3389/fendo.2022.929668
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923
[Journal Article] Mechanical guidance of self-condensation patterns of differentiating progeny2022
- Author(s)
  Matsuzaki Takahisa、Shimokawa Yuko、Koike Hiroyuki、Kimura Masaki、Kawano Yuma、Okuma Nao、Kawamura Ryuzo、Yoneyama Yosuke、Furuichi Yasuro、Hakuno Fumihiko、Takahashi Shin-Ichiro、Nakabayashi Seiichiro、Okamoto Satoshi、Nakauchi Hiromitsu、Taniguchi Hideki、Takebe Takanori、Yoshikawa Hiroshi Y.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 10 Pages: 105109-105109
- DOI
  10.1016/j.isci.2022.105109
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K19924, KAKENHI-PUBLICLY-22H05423, KAKENHI-PROJECT-21H04822, KAKENHI-PROJECT-21H04830, KAKENHI-PROJECT-22H00302, KAKENHI-PROJECT-20H04079, KAKENHI-PROJECT-21H02991, KAKENHI-PROJECT-20K21117
[Journal Article] Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation2022
- Author(s)
  Kobayashi S, Ogasawara N, Watanabe S, Yoneyama Y, Kirino S, Hiraguri Y, Inoue M, Nagata S, Okamoto-Uchida Y, Kofuji S, Shimizu H, Ito G, Mizutani T, Yamauchi S, Kinugasa Y, Kano Y, Nemoto Y, Watanabe M, Tsuchiya K, Nishina H, Okamoto R, Yui S.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1 Pages: 49-49
- DOI
  10.1186/s41232-022-00237-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06544, KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K08048, KAKENHI-PROJECT-22K09680, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03381, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-21H02895, KAKENHI-PROJECT-21H02898
[Journal Article] Mammalian enteral ventilation ameliorates respiratory failure2021
- Author(s)
  Okabe Ryo、Chen-Yoshikawa Toyofumi F.、Yoneyama Yosuke、Yokoyama Yuhei、Tanaka Satona、Yoshizawa Akihiko、Thompson Wendy L.、Kannan Gokul、Kobayashi Eiji、Date Hiroshi、Takebe Takanori
- Journal Title
  
  Med
  
  Volume: 2 Issue: 6 Pages: 773-783
- DOI
  10.1016/j.medj.2021.04.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536, KAKENHI-PROJECT-21H04822
[Journal Article] Isolation and Characterization of Tissue Resident CD29-Positive Progenitor Cells in Livestock to Generate a Three-Dimensional Meat Bud2021
- Author(s)
  Naraoka Yuna、Mabuchi Yo、Yoneyama Yosuke、Suto Eriko Grace、Hisamatsu Daisuke、Ikeda Mami、Ito Risa、Nakamura Tetsuya、Takebe Takanori、Akazawa Chihiro
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 9 Pages: 2499-2499
- DOI
  10.3390/cells10092499
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01753, KAKENHI-PROJECT-19K16536, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-21H03328, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-21K15888, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-21H04822
[Journal Article] Enteral ventilation technology to combat severe respiratory failure2021
- Author(s)
  YONEYAMA Yosuke、OKABE Ryo、TAKEBE Takanori
- Journal Title
  
  Translational and Regulatory Sciences
  
  Volume: 3 Issue: 3 Pages: 93-97
- DOI
  10.33611/trs.2021-015
- NAID
  130008133922
- ISSN
  2434-4974
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536, KAKENHI-PROJECT-21H04822
[Journal Article] Rapid manipulation of mitochondrial morphology in a living cell with iCMM2021
- Author(s)
  Miyamoto Takafumi、Uosaki Hideki、Mizunoe Yuhei、Han Song-Iee、Goto Satoi、Yamanaka Daisuke、Masuda Masato、Yoneyama Yosuke、Nakamura Hideki、Hattori Naoko、Takeuchi Yoshinori、Ohno Hiroshi、Sekiya Motohiro、Matsuzaka Takashi、Hakuno Fumihiko、Takahashi Shin-Ichiro、Yahagi Naoya、Ito Koichi、Shimano Hitoshi
- Journal Title
  
  Cell Reports Methods
  
  Volume: 1 Issue: 4 Pages: 100052-100052
- DOI
  10.1016/j.crmeth.2021.100052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K16536, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064, KAKENHI-PROJECT-19KK0219, KAKENHI-PROJECT-23K23562
[Journal Article] High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell?Derived Organoids2021
- Author(s)
  Shinozawa T, Kimura M, Cai Y, Saiki N, Yoneyama Y, Ouchi R, Koike H, Maezawa M, Zhang RR, Dunn A, Ferguson A, Togo S, Lewis K, Thompson WL, Asai A, Takebe T.
- Journal Title
  
  Gastroenterology
  
  Volume: 160 Issue: 3 Pages: 831-846.e10
- DOI
  10.1053/j.gastro.2020.10.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02800, KAKENHI-PROJECT-19K22416, KAKENHI-PROJECT-19K16536
[Journal Article] Myoblasts With Higher IRS-1 Levels Are Eliminated From the Normal Cell Layer During Differentiation2020
- Author(s)
  Okino Ryosuke、Usui Ami、Yoneyama Yosuke、Takahashi Shin-Ichiro、Hakuno Fumihiko
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 11 Pages: 1-10
- DOI
  10.3389/fendo.2020.00096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16536, KAKENHI-PROJECT-18H03972
[Journal Article] Stiffness distribution analysis in indentation depth direction reveals clear mechanical features of cells and organoids by using AFM2020
- Author(s)
  Naritaka Kobayashi, Shodai Togo, Takahisa Matsuzaki, Kaede Hashiseko, Ryuzo Kawamura, Masami Suganuma, Seiichiro Nakabayashi, Yosuke Yoneyama, Rie Ouchi, Takanori Takebe, Hiroshi Y. Yoshikawa
- Journal Title
  
  Applied Physics Express
  
  Volume: 13 Pages: 9-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16536
[Journal Article] Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids2019
- Author(s)
  Ouchi Rie、et al.
- Journal Title
  
  Cell Metabolism
  
  Volume: 30 Issue: 2 Pages: 374-384
- DOI
  10.1016/j.cmet.2019.05.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01753, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-19K22416, KAKENHI-PROJECT-19K16536, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-18H02800
[Journal Article] Glucose deprivation attenuates sortilin levels in skeletal muscle cells2017
- Author(s)
  Ariga M, Yoneyama Y, Fukushima T, Ishiuchi Y, Ishii T, Sato H, Hakuno F, Nedachi T, Takahashi S
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 3 Pages: 255-268
- DOI
  10.1507/endocrj.EJ16-0319
- NAID
  130005529466
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18766, KAKENHI-PROJECT-16K08077, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15H04583
[Journal Article] The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins.2015
- Author(s)
  Hakuno F, Fukushima T, Yoneyama Y, Kamei H, Ozoe A, Yoshihara H, Yamanaka D, Shibano T, Sone-Yonezawa M, Yu BC, Chida K, Takahashi S.
- Journal Title
  
  Front Endocrinol (Lausanne).
  
  Volume: 6 Pages: 73-73
- DOI
  10.3389/fendo.2015.00073
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15K18766, KAKENHI-PROJECT-15K18799, KAKENHI-PROJECT-15H04583, KAKENHI-PROJECT-24380152, KAKENHI-PROJECT-25221204
[Journal Article] Analysis of insulin receptor substrates signaling dynamics on microstructured surfaces.2015
- Author(s)
  Lanzerstorfer P, Yoneyama Y, Hakuno F, Muller U, Hoglinger O, Takahashi SI, Weghuber J
- Journal Title
  
  FEBS J.
  
  Volume: 282 Issue: 6 Pages: 987-1005
- DOI
  10.1111/febs.13213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380152, KAKENHI-PROJECT-15K18766, KAKENHI-PROJECT-15H04583, KAKENHI-PROJECT-25221204
[Patent] 脂肪性肝疾患を処置することに用いられるための組成物2024
- Inventor(s)
  武部貴則, 米山鷹介
- Industrial Property Rights Holder
  武部貴則, 米山鷹介
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-22K06923
[Patent] 脂肪性肝疾患を処置することに用いられるための組成物2023
- Inventor(s)
  武部貴則, 米山鷹介
- Industrial Property Rights Holder
  武部貴則, 米山鷹介
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-22K06923
[Patent] 細胞注入装置、及び外来細胞を内包するオルガノイドの作成方法2022
- Inventor(s)
  植田裕基、田中伸明、武部貴則、米山鷹介
- Industrial Property Rights Holder
  植田裕基、田中伸明、武部貴則、米山鷹介
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K06923
[Patent] 非アルコール性脂肪性肝炎における線維化進行度および／または前記肝疾患の活動性を推定する方法2022
- Inventor(s)
  武部貴則, 米山鷹介
- Industrial Property Rights Holder
  武部貴則, 米山鷹介
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-22K06923
[Patent] 非アルコール性脂肪性肝炎の線維化進行度を推定する方法2021
- Inventor(s)
  武部貴則、米山鷹介
- Industrial Property Rights Holder
  武部貴則、米山鷹介
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-129760
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K16536
[Patent] 呼吸不全等による低酸素状態の対象を処置することに用いる医薬組成物2020
- Inventor(s)
  武部貴則、米山鷹介、岡部亮、芳川豊史、伊達洋至
- Industrial Property Rights Holder
  武部貴則、米山鷹介、岡部亮、芳川豊史、伊達洋至
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] オルガノイドゲノミクスによる脂肪性肝疾患の病態解明2024
- Author(s)
  米山鷹介
- Organizer
  第12回
- Invited
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] ヒト血管化肝臓オルガノイドを用いた薬剤性血栓性微小血管症の発症機序の解明2023
- Author(s)
  河村峻太郎, 米山鷹介, 佐伯憲和, 森谷千春, 前澤真理, 岡田憲樹, 佐久間康成, 呉運恒, 森建策, 武部貴則
- Organizer
  第22回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] 化学誘導二量体形成法のためのラパマイシン耐性を有するヒトiPS細胞の創出2023
- Author(s)
  米山鷹介、吉野龍之介、大野博、広川貴次、武部貴則、宮本崇史
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] 哺乳類腸呼吸現象の発見とそれを応用した呼吸補助療法の開発2023
- Author(s)
  米山鷹介
- Organizer
  第63回日本呼吸器学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] Genotype-phenotype association strategy for fatty liver diseases using human iPSC-derived organoids2023
- Author(s)
  Yosuke Yoneyama
- Organizer
  EVIDENT Organoid Conference 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] ヒト肝臓オルガノイドパネルを用いた疾患-遺伝子相関解析2023
- Author(s)
  米山鷹介
- Organizer
  日本再生医療学会第3回科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] ヒトiPS 細胞由来デザイナーオルガノイドを用いたバイオ人工肝臓デバイスの構築2023
- Author(s)
  山口仁美、米山鷹介、武部貴則
- Organizer
  第61回日本人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] IGFALS Regulates Non-Alcoholic Steatohepatitis Progression in Mouse, Organoid and Human2023
- Author(s)
  Yosuke Yoneyama, Masato Yoneda, Atsushi Nakajima, Takanori Takebe
- Organizer
  Gordon Research Conference 2023 IGF and Insulin Systems in Physiology and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] Modeling human fatty liver diseases with iPSC-derived organoid2023
- Author(s)
  Yosuke Yoneyama
- Organizer
  Global Regenerative Medicine Trainee Speaker Series
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] 高剛性センサプローブを用いたオルガノイドの粘弾性評価2022
- Author(s)
  渡邉史朗、杉浦広峻、武部貴則、米山鷹介、新井史人
- Organizer
  化学とマイクロ・ナノシステム学会第45回研究会
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] ヒトiPS細胞由来肝臓オルガノイドを用いた脂肪肝に関する病態研究2022
- Author(s)
  米山鷹介
- Organizer
  第６回ラベルフリー評価解析ウェブセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K06923
[Presentation] ヒト肝臓プライマリオルガノイドからのiPS細胞樹立と肝疾患研究への応用2022
- Author(s)
  張カン春、米山鷹介、大津香苗、三好正人、北畑富貴子、新田沙由梨、赤星径一、田邉稔、柿沼晴、朝比奈靖浩、武部貴則
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] ヒト肝臓オルガノイドによるマイ・メディシン2021
- Author(s)
  米山鷹介
- Organizer
  第20回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] INTERCELLULAR RNA TRANSFER-DRIVEN REPROGRAMMING OF HUMAN PLURIPOTENT STEM CELLS INTO NAIVE-LIKE STATE2021
- Author(s)
  Yosuke Yoneyama Takanori Takebe
- Organizer
  ISSCR Tokyo 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] Human Pluripotent Stem Cell-Derived Liver Organoid Manufacturing2021
- Author(s)
  Yosuke Yoneyama
- Organizer
  Olympus Discovery Summit: Advanced Your Imaging
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] Live-cell incubation monitoring and human organoid manufacturing for modeling liver diseases2021
- Author(s)
  Yosuke Yoneyama
- Organizer
  2021 ZISCTI-CSCT Annual Meeting, Satellite Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] 消化器臓器のヒューマンオルガノイドにおけるマルチスケールイメージング2021
- Author(s)
  米山鷹介
- Organizer
  第20回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] ヒューマンオルガノイド技術による脂肪性肝炎病態の再現と工学的手法による新規線維化評価系の構築2020
- Author(s)
  米山鷹介、武部貴則
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] マイクロデバイスによるヒューマン・オルガノイドの機能拡張2020
- Author(s)
  米山鷹介
- Organizer
  第19回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] Conceptual basis of lineage shift between intestinal epithelium and hepatocytes2020
- Author(s)
  Sakurako Kobayashi, Satoshi Watanabe, Yosuke Yoneyama, Kousuke Tanimoto, Ryu Nishimura, Sayaka Nagata, Masami Inoue, Kouhei Suzuki, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Takanori Takebe, Shiro Yui
- Organizer
  Keystone Symposia on Tissue Organoids as Models of Host Physiology and Pathophysiology of Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] INTERCELLULAR RNA TRANSFER-DRIVEN EPIGENETIC REPROGRAMMING OF HUMAN PLURIPOTENT STEM CELLS INTO NAIVE-LIKE STATE2019
- Author(s)
  Yosuke Yoneyama, Ran-Ran Zhang, Masaki Kimura, Takanori Takebe
- Organizer
  ISSCR 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16536
[Presentation] Temporal regulation of insulin-like growth factor signaling by IRS-1-dependent feedback loops2017
- Author(s)
  Yoneyama Y
- Organizer
  Insulin-like signaling and nutrient signaling: universal signaling for extention of healthy lifespan and improvement of quality for humans and animals
- Place of Presentation
  The University of Tokyo, Tokyo, Japan
- Year and Date
  2017-01-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18766
[Presentation] The SCF-b-TRCP E3 ligase complex induces IRS-1 degradation mediated by mTORC1 pathway2017
- Author(s)
  Inamitsu T, Yoneyama Y, Chida K, Hakuno F, Takahashi S
- Organizer
  Gordon Research Conference: IGF & Insulin System in Physiology & Disease
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18766
[Presentation] Roles of IRS-1-induced cell competition in myogenic differentiation2017
- Author(s)
  Usui A, Hakuno F, Yoneyama Y, Kamei H, Chida K, Takahashi S
- Organizer
  Gordon Research Conference: IGF & Insulin System in Physiology & Disease
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18766
[Presentation] Prolonged IGF signaling by IRS-1-mediated control of delayed IGF-IR internalization2017
- Author(s)
  Yoneyama Y, Lanzerstorfer P, Weghuber J, Hakuno F, Takahashi S
- Organizer
  Gordon Research Conference: IGF & Insulin System in Physiology & Disease
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18766
[Presentation] Early embryonic insulin receptor substrate-1 signaling underpins neural crest cell survival contributing to catch-up growth induced by changing environmental oxygen tension in developing zebrafish2017
- Author(s)
  Kamei H, Yoneyama Y, Hakuno F, Sawada R, Shimizu T, Duan C, Takahashi S
- Organizer
  Gordon Research Conference: IGF & Insulin System in Physiology & Disease
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18766
[Presentation] Analysis of receptor tyrosine kinases and G-protein coupled receptor signaling dyanamics on micro-structured surfaces2017
- Author(s)
  Lanzerstorfer P, Yoneyama Y, Hakuno F, Zindel D, Muller U, Krasel C, Buenemann M, Hoeglinger O, Takahashi S, Weghuber J
- Organizer
  Biophysical Society 61th Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18766
[Presentation] SCFユビキチンリガーゼ複合体によるリン酸化依存的なインスリン受容体基質の分解制御2016
- Author(s)
  稲光智美、米山鷹介、千田和広、伯野史彦、高橋伸一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18766

1. 武部貴則 (20612625)

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2. 伯野史彦 (30282700)

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3. 高橋伸一郎 (00197146)

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4. 片岡直行 (60346062)

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5. 増田正人 (60708543)

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6. 西宏起 (90845653)

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7. 山中大介 (10553266)

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8. HISHIKI Takayuki

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9. KOFUJI Satoshi

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10. 吉川洋史

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11. 久松大介

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12. 赤澤智宏

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13. 馬渕洋

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14. 須藤絵里子グレース

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15. 福嶋俊明

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16. 小池博之

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17. 藤井祐

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18. 西脇公俊

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19. 韓松伊

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YONEYAMA YOSUKE 米山 鷹介

Yoneyama Yosuke 米山 鷹介

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Co-Researchers

オルガノイドを活用した活動性MASHの発症機構の解明と予防・治療戦略の開発Principal Investigator

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オルガノイドから導出された早期肝線維化バイオマーカーに基づくヒトNASH病態解析Principal Investigator

Principal Investigator

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生体の糖脂質代謝スイッチを誘導するオルニチン情報伝達経路の同定とその制御

Principal Investigator

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哺乳類腸呼吸メカニズムの理解と制御

Principal Investigator

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Mechanism of intercellular signaling in steatohepatitis using human liver organoidsPrincipal Investigator

Principal Investigator

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Molecular mechanisms for proliferation-differentiation switch of skeletal muscle stem cells in response to metabolic signalingPrincipal Investigator

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[Book] オルガノイドがもたらすライフサイエンス革命「オルガノイドの移植とライブイメージング」2024

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[Book] 肝不全・肝硬変に対する再生療法－最先端の今 「オルガノイド研究の最先端」2021

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[Book] 腸呼吸技術（EVA法）を用いたCOVID-19関連重症呼吸器合併症治療の可能性2021

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[Book] ヒト内胚葉オルガノイド研究の最新動向2021

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[Book] 臨床応用をめざすヒューマンオルガノイド研究2020

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[Journal Article] Advanced Interferometry with 3-D Structured Illumination Reveals the Surface Fine Structure of Complex Biospecimens2024

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[Journal Article] Quality Control of Stem Cell-Based Cultured Meat According to Specific Differentiation Abilities2024

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[Journal Article] Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines2024

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DOI

YONEYAMA YOSUKE 米山鷹介

Yoneyama Yosuke 米山鷹介

[Book] 肝不全・肝硬変に対する再生療法－最先端の今　「オルガノイド研究の最先端」2021