AOKI Kosuke 青木恒介

… Alternative Names

Aoki Kosuke 青木恒介

Less

Researcher Number	10759773
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 客員研究者
Affiliation (based on the past Project Information) *help	2025: 名古屋大学, 医学系研究科, 客員研究者 2024: 名古屋大学, 医学系研究科, 特任講師 2017 – 2023: 名古屋大学, 医学系研究科, 特任助教 2016: 京都大学, 医学研究科, 研究員 2015: 京都大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 神経膠腫 / CRISPR/Cas9 / 遺伝子異常 / FGFR3 / IDH変異 / CRISPRスクリーニング / 治療抵抗性 / 術中診断 / 術中迅速診断 / 遺伝子診断 … More / 低悪性度神経膠腫 / ゲノム / 脳神経疾患 / 予後不良因子 / 予後因子 … More Except Principal Investigator シングルセル解析 / 脳腫瘍 / シングルセル / CRISPR/Cas9ノックアウト / DNAバーコードラベル / 神経膠腫 / CRISPR/Cas9 / 進化トラジェクション / 遺伝子診断 / ゲノム / 尿遺伝子解析 / 数理モデル / 悪性脳腫瘍 / エピゲノム異常 / 染色体構造異常 / マウスモデル / ポドプラニン / キメラ抗原受容体T細胞 / 細胞免疫療法 / ネオアンチゲン Less

Mechanisms of Therapeutic Resistance and Novel Treatment Strategies in FGFR3 Fusion–Positive GliomasPrincipal Investigator
- Principal Investigator
  
  青木恒介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Therapeutic resistance and evolutionary lineages of various subclones in IDH-mutated gliomasPrincipal Investigator
- Principal Investigator
  
  青木恒介
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
The evolutional trajection and precision-medicine to gliomas
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formation
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
Intraoperative rapid and sensitive detection of genetic alterations in lower-grade gliomasPrincipal Investigator
- Principal Investigator
  
  AOKI KOSUKE
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Nagoya University
Prognostic factors of diffuse lower-grade gliomasPrincipal Investigator
- Principal Investigator
  
  Aoki Kosuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurosurgery
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] がん転移学（上）-がん転移のメカニズムと治療戦略:その基礎と臨床-　（19）中枢神経系腫瘍の分子機構2017
- Author(s)
  青木恒介、鈴木啓道、大岡史治、夏目敦至、小川誠司
- Total Pages
  305
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-17K16643
[Journal Article] All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an <i>ex Vivo</i> Brain Tumor Model2023
- Author(s)
  Chattrairat Kunanon、Yasui Takao、Suzuki Shunsuke、Natsume Atsushi、Nagashima Kazuki、Iida Mikiko、Zhang Min、Shimada Taisuke、Kato Akira、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Yanagida Takeshi、Baba Yoshinobu
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 3 Pages: 2235-2244
- DOI
  10.1021/acsnano.2c08526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05778, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-21H01968
[Journal Article] Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy2023
- Author(s)
  Takahashi Hiromi、Yasui Takao、Hirano Masaki、Shinjo Keiko、Miyazaki Yusuke、Shinoda Wataru、Hasegawa Takeshi、Natsume Atsushi、Kitano Yotaro、Ida Mikiko、Zhang Min、Shimada Taisuke、Paisrisarn Piyawan、Zhu Zetao、Ohka Fumiharu、Aoki Kosuke、Rahong Sakon、Nagashima Kazuki、Yanagida Takeshi、Baba Yoshinobu
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 234 Pages: 115318-115318
- DOI
  10.1016/j.bios.2023.115318
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0209, KAKENHI-PROJECT-19K07661, KAKENHI-PROJECT-23K06633, KAKENHI-PROJECT-21K18979, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-21H01968
[Journal Article] Easy-to-use machine learning system for the prediction of IDH mutation and 1p/19q codeletion using MRI images of adult-type diffuse gliomas2023
- Author(s)
  Nishikawa Tomohide、Ohka Fumiharu、Aoki Kosuke、Suzuki Hiromichi、Motomura Kazuya、Yamaguchi Junya、Maeda Sachi、Kibe Yuji、Shimizu Hiroki、Natsume Atsushi、Innan Hideki、Saito Ryuta
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 40 Issue: 2 Pages: 85-92
- DOI
  10.1007/s10014-023-00459-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19591, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-23K24449
[Journal Article] The first-in-human phase I study of a brain-penetrant mutant IDH1 inhibitor DS-1001 in patients with recurrent or progressive IDH1-mutant gliomas2022
- Author(s)
  Natsume Atsushi、et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 25 Issue: 2 Pages: 326-336
- DOI
  10.1093/neuonc/noac155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356
[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021
- Author(s)
  Kitano Yotaro、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Motomura Kazuya、Tanahashi Kuniaki、Hirano Masaki、Naganawa Tsuyoshi、Iida Mikiko、Shiraki Yukihiro、Nishikawa Tomohide、Shimizu Hiroyuki、Yamaguchi Junya、Maeda Sachi、Suzuki Hidenori、Wakabayashi Toshihiko、Baba Yoshinobu、Yasui Takao、Natsume Atsushi
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13 Issue: 15 Pages: 17316-17329
- DOI
  10.1021/acsami.1c01754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21124, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-19KK0228
[Journal Article] Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas.2021
- Author(s)
  Aoki K, Suzuki H, Yamamoto T, Yamamoto KN, Maeda S, Okuno Y, Ranjit M, Kitano Y, Yamaguchi J, Yamazaki S, Nakamura H, Takahashi M, Narita Y, Nakada M, Deguchi S, Mizoguchi M, Momii Y, Muragaki Y, Abe T, Akimoto J, Wakabayashi T, Saito R, Ogawa S, Haeno H, Natsume A.
- Journal Title
  
  Cancer Res.
  
  Volume: 81 Pages: 4861-4873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0228
[Journal Article] Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas.2021
- Author(s)
  Aoki K, Suzuki H, Yamamoto T, Yamamoto KN, Yamazaki S, Nakamura H, Takahashi M, Narita Y, Nakada M, Deguchi S, Mizoguchi M, Momii Y, Muragaki Y, Abe T, Akimoto J, Wakabayashi T, Saito R, Ogawa S, Haeno H, Natsume A.
- Journal Title
  
  Cancer Res.
  
  Volume: 81 Pages: 4861-4873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03789
[Journal Article] Newly established patient-derived organoid model of intracranial meningioma2021
- Author(s)
  Yamazaki Shintaro、Ohka Fumiharu、Hirano Masaki、Shiraki Yukihiro、Motomura Kazuya et al
- Journal Title
  
  Neuro-Oncology
  
  Volume: 23 Issue: 11 Pages: 1936-1948
- DOI
  10.1093/neuonc/noab155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-21K16645, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-20H03511, KAKENHI-PROJECT-20J01889, KAKENHI-PROJECT-20K20598
[Journal Article] Ependymoma-like tumor with mesenchymal differentiation harboring C11orf95-NCOA1/2 or -RELA fusion: A hitherto unclassified tumor related to ependymoma2021
- Author(s)
  Tomomasa R, Arai Y, Kawabata-Iwakawa R, Fukuoka K, Nakano Y, Hama N, Nakata S, Suzuki N, Ishi Y, Tanaka S, Takahashi JA, Yuba Y, Shiota M, Natsume A, Kurimoto M, Shiba Y, Aoki M, Nabeshima K, Enomoto T, Inoue T, Fujimura J, Kondo A, Yao T, Okura N, Hirose T, Sasaki A, Hirato J, Yokoo H, Nobusawa S.
- Journal Title
  
  Brain Pathol .
  
  Volume: 1 Issue: 3 Pages: 1-9
- DOI
  10.1111/bpa.12943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-19K16579, KAKENHI-PROJECT-19K07411, KAKENHI-PROJECT-21K07110
[Journal Article] H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant.2020
- Author(s)
  Maeda S, Ohka F, Okuno Y, Aoki K, Motomura K, Takeuchi K, Kusakari H, Yanagisawa N, Sato S, Yamaguchi J, Tanahashi K, Hirano M, Kato A, Shimizu H, Kitano Y, Yamazaki S, Yamashita S, Takeshima H, Shinjo K, Kondo Y, Wakabayashi T, Natsume A.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 8 Issue: 1 Pages: 8-19
- DOI
  10.1186/s40478-020-0882-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09478, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17K16643, KAKENHI-PROJECT-17K17792, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-20K20598
[Journal Article] Navigated repetitive transcranial magnetic stimulation as preoperative assessment in patients with brain tumors2020
- Author(s)
  Motomura Kazuya、Takeuchi Hiroki、Nojima Ippei、Aoki Kosuke、Chalise Lushun、Iijima Kentaro、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41598-020-65944-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-20K09448, KAKENHI-PROJECT-19K22804, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-17H04748, KAKENHI-PROJECT-19H01091
[Journal Article] Overview of DNA methylation in adult diffuse gliomas2019
- Author(s)
  Aoki Kosuke、Natsume Atsushi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 36 Issue: 2 Pages: 84-91
- DOI
  10.1007/s10014-019-00339-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16643
[Journal Article] Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma2019
- Author(s)
  Ranjit Melissa、Hirano Masaki、Aoki Kosuke、Okuno Yusuke、Ohka Fumiharu、Yamamichi Akane、Kato Akira、Maeda Sachi、Motomura Kazuya、Matsuo Keitaro、Enomoto Atsushi、Ino Yasushi、Todo Tomoki、Takahashi Masahide、Wakabayashi Toshihiko、Kato Takuya、Natsume Atsushi
- Journal Title
  
  Cell Reports
  
  Volume: 26 Issue: 9 Pages: 2274
- DOI
  10.1016/j.celrep.2019.01.109
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-19K21262, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19K18386, KAKENHI-PROJECT-19KK0228
[Journal Article] Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas2019
- Author(s)
  Ohka Fumiharu、Shinjo Keiko、Deguchi Shoichi、Matsui Yusuke et al.
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 19 Pages: 4814-4827
- DOI
  10.1158/0008-5472.can-19-1272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18151, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04899, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-17K07247
[Journal Article] Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping.2019
- Author(s)
  Motomura K, Chalise L, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Yamaguchi J, Shimizu H, Wakabayashi T, Natsume A.
- Journal Title
  
  J Neurosurg.
  
  Volume: 17 Issue: 6 Pages: 1-9
- DOI
  10.3171/2019.3.jns19211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18H02911
[Journal Article] Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide2019
- Author(s)
  NATSUME Atsushi、HIRANO Masaki、RANJIT Melissa、AOKI Kosuke、WAKABAYASHI Toshihiko
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 59 Issue: 8 Pages: 293-298
- DOI
  10.2176/nmc.ra.2019-0049
- NAID
  130007690186
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0228
[Journal Article] A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR2018
- Author(s)
  Hirano Masaki、Ohka Fumiharu、Maeda Sachi、Chalise Lushun、Yamamichi Akane、Aoki Kosuke、Kato Akira、Tanahashi Kuniaki、Motomura Kazuya、Nishimura Yusuke、Hara Masahito、Shinjo Keiko、Kondo Yutaka、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: - Issue: 2 Pages: 97-105
- DOI
  10.1007/s10014-018-0310-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16643, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-17H03582, KAKENHI-PLANNED-17H06356
[Journal Article] Immunohistochemical ATRX expression is not a surrogate for 1p19q codeletion2018
- Author(s)
  Yamamichi Akane、Ohka Fumiharu、Aoki Kosuke、Suzuki Hiromichi、Kato Akira、Hirano Masaki、Motomura Kazuya、Tanahashi Kuniaki、Chalise Lushun、Maeda Sachi、Wakabayashi Toshihiko、Kato Yukinari、Natsume Atsushi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: - Issue: 2 Pages: 106-113
- DOI
  10.1007/s10014-018-0312-5
- NAID
  120006496406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-16K10748
[Journal Article] Prognostic relevance of genetic alterations in diffuse lower-grade gliomas2017
- Author(s)
  Aoki Kosuke、Nakamura Hideo、Suzuki Hiromichi et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 20 Issue: 1 Pages: 66-77
- DOI
  10.1093/neuonc/nox132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10761, KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H00758, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-15K10337, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-15H05325
[Journal Article] Significance of perivascular tumour cells defined by CD109 expression in progression of glioma2017
- Author(s)
  Shiraki Yukihiro、Mii Shinji、Enomoto Atsushi、Momota Hiroyuki、Han Yi-Peng、Kato Takuya、Ushida Kaori、Kato Akira、Asai Naoya、Murakumo Yoshiki、Aoki Kosuke、Suzuki Hiromichi、Ohka Fumiharu、Wakabayashi Toshihiko、Todo Tomoki、Ogawa Seishi、Natsume Atsushi、Takahashi Masahide
- Journal Title
  
  The Journal of Pathology
  
  Volume: 243 Issue: 4 Pages: 468-480
- DOI
  10.1002/path.4981
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08731, KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26253073, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-15H02822
[Journal Article] A novel all-in-one intraoperative genotyping system for IDH1-mutant glioma.2017
- Author(s)
  Ohka F, Yamamichi A, Kurimoto M, Motomura K, Tanahashi K, Suzuki H, Aoki K, Deguchi S, Chalise L, Hirano M, Kato A, Nishimura Y, Hara M, Kato Y, Wakabayashi T, Natsume A.
- Journal Title
  
  Brain Tumor Pathol.
  
  Volume: 印刷中 Issue: 2 Pages: 91-97
- DOI
  10.1007/s10014-017-0281-0
- NAID
  120006331835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-16K10748, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-17K16643
[Presentation] Mathematical prediction for precision medicine of CNS glial tumors2019
- Author(s)
  Kosuke Aoki（17人中1番目）, Atsushi Natsume (演者：17人中17番目）
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] Classification and grading of diffuse astrocytic tumors2018
- Author(s)
  Kosuke Aoki
- Organizer
  The 5th International Symposium of Brain Tumor Pathology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16643
[Presentation] 低悪性度神経膠腫における遺伝子異常の全貌2018
- Author(s)
  青木恒介
- Organizer
  第１９回日本分子脳神経外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16643
[Presentation] 放射線や化学療法がWHO grade IIびまん性神経膠腫の腫瘍進展と悪性転化に与える影響2017
- Author(s)
  青木恒介、山本高士、山本君代、鈴木啓道、大岡史治、Melissa Ranjit、本村和也、中村英夫、成田善孝、高橋雅道、吉本幸司、籾井泰朋、村垣善浩、若林俊彦、波江野洋、夏目敦至
- Organizer
  第35回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16643
[Presentation] グレードII, IIIグリオーマの分子診断におけるATRX免疫組織染色は 1p/19q共欠失解析のサロゲートとして有用か？2017
- Author(s)
  山道茜, 大岡史治, 青木恒介, 加藤彰, Melissa Ranjit, Chalise Lushun, 平野雅規, 棚橋邦明, 本村和也, 松原年生, 鈴木秀謙, 若林俊彦, 加藤幸成, 夏目敦至
- Organizer
  第76回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16643
[Presentation] Mathematic model of tumor development and malignant transformation in WHO grade II diffuse glioma2017
- Author(s)
  青木恒介、山本高士、山本君代、鈴木啓道、大岡史治、Melissa Ranjit、本村和也、中村英夫、成田善孝、高橋雅道、吉本幸司、籾井泰朋、村垣善浩、若林俊彦、波江野洋、夏目敦至
- Organizer
  第76回日本脳神経外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16643
[Presentation] Genetic subtype-specific prognostic significance of genetic alterations in lower-grade gliomas2016
- Author(s)
  Kosuke Aoki, Hiromichi Suzuki, Hideo Nakamura, Keitaro Matsuo, Kazuya Motomura, Fumiharu Ohka, Masahiro Mizoguchi, Yasutomo Momii, Yoshihiro Muragaki, Reiko Watanabe, Ichiro Ito, Satoru Miyano, Toshihiko Wakabayashi, Atsushi Natsume, Seishi Ogawa
- Organizer
  American Asspociation for cancer research 2016 annual meeting
- Place of Presentation
  New Orleans, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] Comprehensive mutational and cytogenetic analysis revealed genetic prognostic factors in grade II and III gliomas.2016
- Author(s)
  Kosuke Aoki, Hiromichi Suzuki, Hideo Nakamura, Keitaro Matsuo, Kazuya Motomura, Fumiharu Ohka, Masahiro Mizoguchi, Yasutomo Momii, Yoshihiro Muragaki, Reiko Watanabe, Ichiro Ito, Toshihiko Wakabayashi, Atsushi Natsume, Seishi Ogawa
- Organizer
  21th ANNUAL SOCIETY FOR NEURO-ONCOLOGY SCIENTIFIC MEETING
- Place of Presentation
  Scottsdale, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] Comprehensive mutational and cytogenetic analysis revealed prognostic impacts of genetic alterations in grade II and III gliomas2016
- Author(s)
  K Aoki, A Natsume, H Suzuki, S Ogawa, T Wakabayashi
- Organizer
  KEYSTONE SYMPOSIA THE CANCER GENOME (Q1)
- Place of Presentation
  Alberta, Canada
- Year and Date
  2016-02-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] Prognostic implications of genetic alterations from comprehensive genetic profiling in diffuse lower-grade gliomas2016
- Author(s)
  Kosuke Aoki, Hiromichi Suzuki, Keitaro Matsuo, Keisuke Kataoka, Teppei Shimamura, Yasunobu Nagata, Tetsuichi Yoshizato, Masashi Sanada, Satoru Miyano, Toshihiko Wakabayashi, Atsushi Natsume and Seishi Ogawa
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] Genetic subtype-specific prognostic significance of genetic alterations in lower-grade gliomas2016
- Author(s)
  Kosuke Aoki, Hiromichi Suzuki, Hideo Nakamura, Keitaro Matsuo, Kazuya Motomura, Fumiharu Ohka, Masahiro Mizoguchi, Yasutomo Momii, Yoshihiro Muragaki, Reiko Watanabe, Ichiro Ito, Satoru Miyano, Toshihiko Wakabayashi, Atsushi Natsume, Seishi Ogawa
- Organizer
  American Asspociation for cancer research 2016 annual meeting
- Place of Presentation
  New Orleans, TX, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] 大規模ゲノム解析から明らかとなったgrade II, III 神経膠腫における遺伝学的予後予測因子2016
- Author(s)
  青木恒介、鈴木啓道、中村英夫、松尾恵太郎、本村和也、大岡史治、椎名諭、山本高士、溝口昌弘、籾井泰朋、村垣善浩、眞田昌、宮野悟、若林俊彦、小川誠司、夏目敦至
- Organizer
  第75回日本脳神経外科学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] Prognostic significance of genetic alterations from comprehensive analysis in lower-grade gliomas2015
- Author(s)
  KOSUKE AOKI, Hiromichi Suzuki, Hideo Nakamura, Kazuya Motomura, Fumiharu Ohka, Masahiro Mizoguchi, Yasutomo Momii, Yoshihiro Muragaki, Reiko Watanabe, Ichiro Ito, Satoru Miyano, Toshihiko Wakabayashi, Seishi Ogawa, Atsushi Natsume.
- Organizer
  20th ANNUAL SOCIETY FOR NEURO-ONCOLOGY SCIENTIFIC MEETING
- Place of Presentation
  San Antonio, TX, USA
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] Prognostic relevance of comprehensive genetic profiling in lower-grade gliomas2015
- Author(s)
  Kosuke Aoki, Hiromichi Suzuki, Kenichi Chiba, Yuichi Shiraishi, Tatsuya Abe, Teppei Shimamura, Atsushi Niida, Masashi Sanada,Masashi Miyano, Toshihiko Wakabayashi, Atsushi Natsume, and Seishi Ogawa
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] 低悪性度神経膠腫700例における大規模ゲノム解析と臨床、病理所見から得られた予後予測因子2015
- Author(s)
  青木恒介, 鈴木啓道, 中村英夫, 本村和也, 大岡史治, 椎名諭, 山本高士, 溝口昌弘, 籾井泰朋, 村垣善浩, 眞田昌, 宮野悟, 若林俊彦, 小川誠司, 夏目敦至
- Organizer
  第74回日本脳神経外科学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15H06339
[Presentation] WHO grade II/III 神経膠腫700例の大規模ゲノム解析から得られた遺伝学的予後予測因子2015
- Author(s)
  青木恒介、鈴木啓道、中村英夫、松尾恵太郎、本村和也、大岡史治、椎名諭、山本高士、溝口昌弘、籾井泰朋、村垣善浩、眞田昌、宮野悟、若林俊彦、小川誠司、夏目敦至
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  京都
- Year and Date
  2015-12-06
- Data Source
  KAKENHI-PROJECT-15H06339

1. 大岡史治 (10725724)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. Natsume Atsushi (30362255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 平野雅規 (40823076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 加藤彰 (50793056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 日野原邦彦 (50549467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 前田紗知 (20962905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YASUI Takao

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. NAKAMURA Hideo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. HIDE Takuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. MOMOTA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 新城恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 若林俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 松井佑介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 本村和也

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 鈴木啓道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AOKI Kosuke 青木 恒介

Aoki Kosuke 青木 恒介

Research Projects

Research Products

Co-Researchers

Mechanisms of Therapeutic Resistance and Novel Treatment Strategies in FGFR3 Fusion&#8211;Positive GliomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic resistance and evolutionary lineages of various subclones in IDH-mutated gliomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The evolutional trajection and precision-medicine to gliomas

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intraoperative rapid and sensitive detection of genetic alterations in lower-grade gliomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prognostic factors of diffuse lower-grade gliomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] がん転移学（上）-がん転移のメカニズムと治療戦略:その基礎と臨床- （19）中枢神経系腫瘍の分子機構2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an <i>ex Vivo</i> Brain Tumor Model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Easy-to-use machine learning system for the prediction of IDH mutation and 1p/19q codeletion using MRI images of adult-type diffuse gliomas2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The first-in-human phase I study of a brain-penetrant mutant IDH1 inhibitor DS-1001 in patients with recurrent or progressive IDH1-mutant gliomas2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas.2021

Author(s)

Journal Title

Data Source

[Journal Article] Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas.2021

Author(s)

Journal Title

Data Source

[Journal Article] Newly established patient-derived organoid model of intracranial meningioma2021

AOKI Kosuke 青木恒介

Aoki Kosuke 青木恒介

Mechanisms of Therapeutic Resistance and Novel Treatment Strategies in FGFR3 Fusion–Positive GliomasPrincipal Investigator

[Book] がん転移学（上）-がん転移のメカニズムと治療戦略:その基礎と臨床-　（19）中枢神経系腫瘍の分子機構2017