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Otani Shinji  大谷 真二

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OTANI SHINJI  大谷 真二

SHINJI OTANI  大谷 真二

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Researcher Number 10770779
Other IDs
Affiliation (Current) 2025: 愛媛大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help 2023: 愛媛大学, 医学部付属病院, 准教授
2023: 愛媛大学, 医学部附属病院, 准教授
2021 – 2022: 愛媛大学, 医学部附属病院, 助教
2020 – 2021: 岡山大学, 大学病院, 助教
2016 – 2018: 岡山大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55040:Respiratory surgery-related / Respiratory surgery
Except Principal Investigator
Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55040:Respiratory surgery-related / Medical pharmacy
Keywords
Principal Investigator
虚血再灌流障害 / 肺移植 / HMGB1 / HMGB1 / 移植・再生医療 / MAPK / マウス / MAPK/ERK経路 / SPRED2
Except Principal Investigator
肺移植 … More / 拒絶反応 / 個別化医療 / バイオマーカー / 慢性移植肺機能不全(CLAD) / 早期移植肺機能不全(PGD) / 細胞外遊離DNA(cfDNA) / ナノポアシーケンサー / S100 / 抗S100A8/A9中和抗体 / S100A9 / S100A8 / 虚血再灌流障害 / 移植 / 遺伝子 / 薬学 / ミコフェノールモフェチル酸 / UGT / ゲノム不安定性 / メチル化遺伝子 / 個別化薬物療法 / ミコフェノール酸モフェチル / UGT1A8 / ミコフェノール酸 / 免疫抑制薬 / メチル化DNA Less
  • Research Projects

    (6 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (16 People)
  •  ナノポアシーケンサーを用いた移植肺障害の革新的な迅速診断法の開発と病態解明

    • Principal Investigator
      杉本 誠一郎
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Okayama University
  •  転写制御因子を標的とした新規肺虚血再灌流障害制御法の開発と臨床応用Principal Investigator

    • Principal Investigator
      大谷 真二
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
  •  Elucidation of the role of S100A8/A9 in pulmonary ischemia-reperfusion injury and development of new therapeutic strategies

    • Principal Investigator
      Okazaki Mikio
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  Therapeutic effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in micePrincipal Investigator

    • Principal Investigator
      OTANI SHINJI
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Ehime University
      Okayama University
  •  Development of individualization drug therapy for mycophenolate mofechil focused on the DNA methylation of UGT (UDP- glucuronosyltransferase) 1A8

    • Principal Investigator
      SUNO MANABU
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Okayama University
  •  SPRED-2 is necessary to protect against lung graft injury after mouse lung transplantationPrincipal Investigator

    • Principal Investigator
      SHINJI OTANI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory surgery
    • Research Institution
      Okayama University

All 2021 2018

All Journal Article Presentation

  • [Journal Article] Protective effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice2021

    • Author(s)
      Nakata Kentaro、Okazaki Mikio、Shimizu Dai、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Otani Shinji、Yamamoto Hiromasa、Sugimoto Seiichiro、Yamane Masaomi、Ousaka Daiki、Ohara Toshiaki、Matsukawa Akihiro、Nishibori Masahiro、Toyooka Shinichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 573 Pages: 164-170

    • DOI

      10.1016/j.bbrc.2021.08.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09305, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K09176
  • [Presentation] 肺移植患者における血中ミコフェノール酸トラフ濃度/投与量比に与えるUGT1A8の影響について2018

    • Author(s)
      須野学,内嶺陽平,伊藤明花,松本准,藤吉正哉,有吉範高,大谷真二,大藤剛宏
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-16K08402
  • [Presentation] 肺移植患者におけるCYP3A4およびCYP3A5遺伝子多型の組み合わせがタクロリムス血中トラフ濃度/投与量比におよぼす影響2018

    • Author(s)
      須野学,内嶺陽平,伊藤明花,松本准,有吉範高,大谷真二,大藤剛宏
    • Organizer
      第27回日本医療薬学会
    • Data Source
      KAKENHI-PROJECT-16K08402
  • 1.  Okazaki Mikio (50467750)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  杉本 誠一郎 (40570148)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  山根 正修 (20432643)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  坂上 倫久 (20709266)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  豊岡 伸一 (30397880)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  阪口 政清 (70379840)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  三好 健太郎 (50534773)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  橋本 好平 (10959828)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SUNO MANABU (20621189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  永坂 岳司 (30452569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  有吉 範高 (00243957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  山本 寛斉 (40467733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  木下 理恵 (40518297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  王 登莉 (40815693)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  西堀 正洋 (50135943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  OTO Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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