Kawata Manabu 河田学

… Alternative Names

河田学カワタマナブ

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Researcher Number	10803174
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター病院, 医員
Affiliation (based on the past Project Information) *help	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター, 医員 2023: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター, 研究員 2020: 日本学術振興会, 海外特別研究員 2019: 東京大学, 医学部附属病院, 登録研究員 2018: 東京大学, 医学部附属病院, 特任研究員 2017: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / 0906:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 変形性関節症 / iPS細胞 / 軟骨細胞 / KLF4 / 再生医学 / エピゲノム解析 / ヒト多能性幹細胞 / 低分子化合物 / 多能性幹細胞 Except Principal Investigator 細胞製剤 … More / 整形外科学 / 変形性関節症 / 分化誘導条件 / 細胞製剤の開発 / ヒトES細胞 / 変形性膝関節症 Less

転写因子KLF4に依拠した、変形性関節症の病態解明および革新的治療法の開発Principal Investigator
- Principal Investigator
  
  河田学
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Tokyo Metropolitan Institute for Geriatrics and Gerontology
転写因子KLF4に依拠した、変形性関節症の新規治療候補薬剤の網羅的探索および機能解析Principal Investigator
- Principal Investigator
  
  河田学
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of induced Drug-Cells for treating Arthritis (DCA) using human ES cells for osteoarthritis
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Strategic research on cartilage development and regeneration using the chondrocyte differentiation method of human iPS cells by small-molecule compoundsPrincipal Investigator
- Principal Investigator
  
  Kawata Manabu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
低分子化合物を用いたiPS細胞の軟骨分化誘導法による軟骨再生医療及び軟骨分化研究Principal Investigator
- Principal Investigator
  
  河田学
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo

All 2019 2018 2017

All Journal Article Presentation

[Journal Article] Meniscal bearing dislocation while rolling over in sleep following Oxford medial unicompartmental knee arthroplasty2019
- Author(s)
  Kawaguchi Kohei、Inui Hiroshi、Taketomi Shuji、Yamagami Ryota、Kono Kenichi、Nakazato Keiu、Kawata Manabu、Tanaka Sakae
- Journal Title
  
  The Knee
  
  Volume: 26 Issue: 1 Pages: 267-272
- DOI
  10.1016/j.knee.2018.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17K10955
[Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds2019
- Author(s)
  Kawata Manabu、Mori Daisuke、Kanke Kosuke、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Yano Fumiko、Masaki Hideki、Otsu Makoto、Nakauchi Hiromitsu、Tanaka Sakae、Saito Taku
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 3 Pages: 530-544
- DOI
  10.1016/j.stemcr.2019.07.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Chronological Changes in Anterior Knee Stability after Anatomical Anterior Cruciate Ligament Reconstruction Using Bone?Patellar Tendon?Bone and Hamstring Grafts2019
- Author(s)
  Kawaguchi Kohei、Taketomi Shuji、Inui Hiroshi、Yamagami Ryota、Nakazato Keiu、Takagi Kentaro、Kage Tomofumi、Kawata Manabu、Tanaka Sakae
- Journal Title
  
  The Journal of Knee Surgery
  
  Volume: - Issue: 06 Pages: 659-664
- DOI
  10.1055/s-0039-1700809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17K10955
[Journal Article] Surgical timing of anterior cruciate ligament reconstruction to prevent associated meniscal and cartilage lesions2018
- Author(s)
  Taketomi S, Inui H, Yamagami R, Kawaguchi K, Nakazato K, Kono K, Kawata M, Nakagawa T, Tanaka S
- Journal Title
  
  J Orthop Sci
  
  Volume: 23 Issue: 3 Pages: 546
- DOI
  10.1016/j.jos.2018.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17H06637
[Journal Article] Atopic dermatitis is a novel demographic risk factor for surgical site infection after anterior cruciate ligament reconstruction2018
- Author(s)
  Kawata Manabu、Sasabuchi Yusuke、Taketomi Shuji、Inui Hiroshi、Matsui Hiroki、Fushimi Kiyohide、Yasunaga Hideo、Tanaka Sakae
- Journal Title
  
  Knee Surgery, Sports Traumatology, Arthroscopy
  
  Volume: 26 Issue: 12 Pages: 3699-3705
- DOI
  10.1007/s00167-018-4958-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17K10955
[Journal Article] Annual trends in arthroscopic meniscus surgery: Analysis of a national database in Japan2018
- Author(s)
  Kawata Manabu、Sasabuchi Yusuke、Taketomi Shuji、Inui Hiroshi、Matsui Hiroki、Fushimi Kiyohide、Chikuda Hirotaka、Yasunaga Hideo、Tanaka Sakae
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 4 Pages: e0194854-e0194854
- DOI
  10.1371/journal.pone.0194854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17K10955
[Journal Article] Annual trends in knee arthroplasty and tibial osteotomy: Analysis of a national database in Japan2017
- Author(s)
  Kawata M, Sasabuchi Y, Inui H, Taketomi S, Matsui H, Fushimi K, Chikuda H, Yasunaga H, Tanaka S
- Journal Title
  
  Knee
  
  Volume: 24 Issue: 5 Pages: 1198-1205
- DOI
  10.1016/j.knee.2017.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-17H06637
[Presentation] 2種類の低分子化合物によるヒトiPS細胞の軟骨分化誘導法の確立2019
- Author(s)
  河田学、齋藤琢、矢野文子、田中栄
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] 2種類の低分子化合物によるヒト多能性幹細胞の軟骨細胞への分化誘導法の確立2019
- Author(s)
  河田学、齋藤琢、田中栄
- Organizer
  第5回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] 2種類の低分子化合物による、簡便で高効率なヒト多能性幹細胞の軟骨細胞への分化誘導法2019
- Author(s)
  河田学、齋藤琢、矢野文子、田中栄
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] 二顆以上の病変に対する各種ACL温存人工関節手術(BCR TKA、BiKA)の短期成績比較2018
- Author(s)
  乾洋, 武冨修治, 山神良太, 川口航平, 中里啓佑, 河野賢一, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] 解剖学的長方形骨孔前十字靱帯再建術後の脛骨骨孔拡大に影響する因子の検討2018
- Author(s)
  中里啓佑, 武冨修治, 乾洋, 山神良太, 河野賢一, 川口航平, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] BCR TKAとBCS TKAにおける術中回旋キネマティクスの比較2018
- Author(s)
  川口航平, 乾洋, 武冨修治, 山神良太, 河野賢一, 中里啓佑, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] 正常膝における屈曲動作と伸展動作の生体内3次元動態比較2018
- Author(s)
  河野賢一, 冨田哲也, 山崎隆治, 武冨修治, 乾洋, 山神良太, 川口航平, 中里啓佑, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] Oxford UKAにおけるインプラント設置角度と術後脛骨側radiolucent lineの検討2018
- Author(s)
  山神良太, 乾洋, 武冨修治, 河野賢一, 中里啓佑, 川口航平, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] Arthroscopic surgery for children/Arthroscopic surgery for patients under 16 years old2018
- Author(s)
  武冨修治, 乾洋, 山神良太, 川口航平, 中里啓佑, 河野賢一, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] Runx3は関節軟骨に保護的に作用する2018
- Author(s)
  永田向生, 張成虎, 矢野文子, 河田学, 牧井勇磨, 田中栄, 齋藤琢
- Organizer
  第91回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] 両十字靱帯機能温存型人工膝関節全置換術の荷重・非荷重深屈曲動作における生体内三次元動態解析2018
- Author(s)
  河野賢一, 乾洋, 冨田哲也, 山崎隆治, 武冨修治, 山神良太, 川口航平, 中里啓佑, 河田学, 菅本一臣, 田中栄
- Organizer
  第91回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] TKAとUKAでは患者が満足する要因が異なる2018
- Author(s)
  乾洋, 武冨修治, 山神良太, 川口航平, 中里啓佑, 河野賢一, 河田学, 田中栄
- Organizer
  第10回日本関節鏡・膝・スポーツ整形外科学会
- Data Source
  KAKENHI-PROJECT-18K16645
[Presentation] Runx3は関節軟骨に保護的に作用する2018
- Author(s)
  永田向生, 張成虎, 矢野文子, 河田学, 牧井勇磨, 田中栄, 齋藤琢
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16645

1. Saito Taku (30456107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 森大典 (60835354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. TAKETOMI Shuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 山神良太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 乾洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawata Manabu 河田 学

河田 学 カワタ マナブ

Research Projects

Research Products

Co-Researchers

転写因子KLF4に依拠した、変形性関節症の病態解明および革新的治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写因子KLF4に依拠した、変形性関節症の新規治療候補薬剤の網羅的探索および機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of induced Drug-Cells for treating Arthritis (DCA) using human ES cells for osteoarthritis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Strategic research on cartilage development and regeneration using the chondrocyte differentiation method of human iPS cells by small-molecule compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低分子化合物を用いたiPS細胞の軟骨分化誘導法による軟骨再生医療及び軟骨分化研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Meniscal bearing dislocation while rolling over in sleep following Oxford medial unicompartmental knee arthroplasty2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronological Changes in Anterior Knee Stability after Anatomical Anterior Cruciate Ligament Reconstruction Using Bone?Patellar Tendon?Bone and Hamstring Grafts2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Surgical timing of anterior cruciate ligament reconstruction to prevent associated meniscal and cartilage lesions2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Atopic dermatitis is a novel demographic risk factor for surgical site infection after anterior cruciate ligament reconstruction2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Annual trends in arthroscopic meniscus surgery: Analysis of a national database in Japan2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Annual trends in knee arthroplasty and tibial osteotomy: Analysis of a national database in Japan2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 2種類の低分子化合物によるヒトiPS細胞の軟骨分化誘導法の確立2019

Author(s)

Organizer

Data Source

[Presentation] 2種類の低分子化合物によるヒト多能性幹細胞の軟骨細胞への分化誘導法の確立2019

Author(s)

Organizer

Data Source

[Presentation] 2種類の低分子化合物による、簡便で高効率なヒト多能性幹細胞の軟骨細胞への分化誘導法2019

Author(s)

Kawata Manabu 河田学

河田学カワタマナブ