Saito Taku 齋藤琢

… Alternative Names

SAITO Taku 齋藤琢

斉藤琢サイトウタク

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Researcher Number	30456107
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 医学部附属病院, 准教授 2015 – 2016: 東京大学, 医学部附属病院, 講師 2014: 東京大学, 医学部附属病院, 准教授 2010 – 2014: The University of Tokyo, 医学部附属病院, 特任准教授 2013: 東京大学, 医学部附属病院, 助教 … More 2012: 東京大学, 医学部附属病院, 准教授 2011: 東京大学, 医学部・附属病院, 特任准教授 2009: The University of Tokyo, 医学部・附属病院, 特任助教 2009: 東京大学, 医学部附属病院, 特任助教 2008: The University of Tokyo, 大学院・医学系研究科, 特任助教 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56020:Orthopedics-related / Surgery related to the biological and sensory functions and related fields Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Basic Section 57010:Oral biological science-related / Broad Section I / Basic Section 57060:Surgical dentistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Kidney internal medicine
Keywords	Principal Investigator 変形性関節症 / 整形外科学 / 軟骨細胞 / 再生医療 / 軟骨代謝学 / 滑膜 / 関節運動 / 関節恒常性 / 関節軟骨 / iPS細胞 … More / 再生医学 / 骨・軟骨代謝学 / 腱靭帯修復 / メカノバイオロジー / 細胞製剤 / 分化誘導条件 / 細胞製剤の開発 / ヒトES細胞 / 変形性膝関節症 / 廃用症候群 / 軟骨 / 骨軟骨代謝学 / 関節最表層 / 筋肉 / 関節痛 / 運動器疾患 / Prg4 / ルブリシン / 動作解析 / 軟骨再生 / 再生医療学 / メカニカルストレス / 関節軟骨細胞 / 軟骨代謝 / 幹細胞 / インジケーター / 骨 / HIF2A / 転写因子 / 軟骨内骨化 / 発生・分化 / 細胞・組織 … More Except Principal Investigator 変形性関節症 / 整形外科学 / 軟骨 / 関節軟骨 / 軟骨細胞 / 滑膜 / シングルセル解析 / 変形性膝関節症 / 骨粗鬆症 / 軟骨代謝 / 関節リウマチ / メカニカルストレス / 関節炎 / 神経障害性疼痛 / 関節 / ルブリシン / Prg4 / 関節恒常性 / 運動器 / ハイドロゲル / 癒着 / 運動器恒常性維持 / 滑膜組織 / 軟骨分化 / HIF-1α / 後縦靭帯骨化症 / 関節症 / 骨軟骨代謝学 / 骨・軟骨代謝学 / 軟骨内骨化 / 骨 / Hif2a / Hif-2α / 関節支持組織 / 腱靭帯 / 異所性骨化 / エストロゲン / 性ホルモン / 全身性免疫システム / 間葉系幹細胞 / メカノバイオロジー / 老化 / 加齢 / 超硫黄分子 / 血友病 / 血友病性関節症 / 硬組織 / BMP / 免疫細胞 / 骨免疫 / JAK-STAT経路 / アロディニア / JAK-STAT pathway / 後根神経節 / 慢性疼痛 / 関節炎モデル / 神経 / 神経癒着 / 手術 / 医療・福祉 / 整形外学学 / 転写制御機構 / ChIPシークエンス / RNAシークエンス / ２型コラーゲン / Runx2 / Runx3 / 関節最表層 / SFZ / Superficial zone (SFZ) / 移植・再生医療 / 半月板 / 酸化還元 / エネルギー代謝 / 成長板 / 骨代謝 / RSS / 活性イオウ分子種 / 骨芽細胞 / 破骨細胞 / 骨リモデリング / 活性硫黄分子種 / HIF-2α / 酸素濃度勾配 / 低身長 / 骨分化 / 骨伸長 / Kenny-Caffey 症候群 / osteocraniostenosis / Kenny-Caffey 症候群2型 / FAM111A / 遺伝子改変マウス / Osteocraniostenosis / Kenny-Caffey症候群 / 線維芽細胞 / マクロファージ / 筋萎縮 / 抗老化 / 炎症 / 身体不活動 / 抗炎症 / 恒常性維持 / 生体恒常性 / リハビリテーション / 適度な運動 / 3Dプリンター / コラーゲン / 軟骨基質 / ヒト脂肪組織幹細胞 / I型コラーゲン / 腱癒着 / 腱 / 運動器学 / 統合運動器学 / ヒトゲノム解析 / 運動器科学 / 軟骨前駆細胞 / メカノセンサー / Fluid Flow Shear Stress / Lubricin / メカノトランスデューサー / 関節軟骨表層 / Trpv2 / メカノセンシティブイオンチャネル / NFκB / HIF-1alpha / ADAMTSファミリー / 椎間板 / フィブリリン / 成長障害 / ADAMTS17 / ADAMTS10 / 動物モデル / 足関節軟骨 / 膝関節軟骨 / 膝関節 / 足関節 / 椎間板変性 / Wntシグナル / 骨化 / 後縦靭帯 / 靱帯 / Rspo2 / GWAS / OPLL / Wnt経路 / RSPO2 / 頚椎後縦靭帯骨化症 / Tace / 関節病学 / S100 / Notchシグナル / Adam17 / Camk2 / Hes1 / 副甲状腺ホルモン / Gαシグナル / 骨・軟骨代謝 / 細胞・組織 / アディポネクチン / レジスチン / アディポカイン / ゲノムワイド関連解析 / 変形性腰椎症 / 脊椎脊髄病学 / 幹細胞 / 四肢機能再建学 / 高リン血症 / 高カリウム血症 / 低カルシウム血症 / 腎電解質代謝 / カルシウム感知受容体 / 遺伝子治療3 / 遺伝子治療 / 骨異栄養症 / 慢性腎不全 / 低Ca血症 / 腎電解質異常 / Ca感知受容体 / 副甲状腺機能低下症 / 腎機能低下 / カルシウム代謝 / バーター症候群 / ゲノム / 疫学 / 画像解析 / 遺伝子 / p63 / 転写因子 / 軟骨代謝学 Less

Prediction of Bone Mineral Density Trends and Risk of Developing Fragility Fractures by Applying AI Osteoporosis Diagnosis Assistance System
- Principal Investigator
  
  茂呂徹
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
関節の恒常性維持と破綻における超硫黄分子の機能解明に基づく関節疾患治療の基盤構築
- Principal Investigator
  
  宮本洋一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Showa University
関節構成体の加齢変容と力学的ストレスによる修飾機構の全貌
- Principal Investigator
  
  武冨修治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Establishment of an integrated locomotive science including spatiotemporal dynamics of bone-articular cells
- Principal Investigator
  
  田中栄
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  The University of Tokyo
関節運動に呼応した滑膜-軟骨連関から紐解く関節の恒常性維持機構Principal Investigator
- Principal Investigator
  
  齋藤琢
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Development of tendon/ligament repair modulater using a chemically modified Tetra-PEG gel with signal transduction capabilityPrincipal Investigator
- Principal Investigator
  
  齋藤琢
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
全身性免疫システムによる神経障害性疼痛の制御機構
- Principal Investigator
  
  里貴史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
関節支持組織の前駆細胞と性ホルモン受容体に着眼した、運動器変性疾患の起源の解明
- Principal Investigator
  
  大友望
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Arthroprotective effects of the transcription factor Hif-2alpha in cartilage and synovium.
- Principal Investigator
  
  河野賢一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
血友病性関節症における関節障害発生機序の詳細
- Principal Investigator
  
  寺島明日香
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Development of Technology for Preventing Nerve Adhesion and Promoting Nerve Repair Using Tetra-PEG Gel
- Principal Investigator
  
  Morizaki Yutaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Analysis of the mechanism of chronic pain in joint diseases using comprehensive expression analysis and single cell analysis.
- Principal Investigator
  
  Taketomi Shuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Identification of anti-inflammatory subsets of MSCs and their clinical applicationPrincipal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Elucidation of bone formation promoting function by BMP agonist KCP, and application to hard tissue reconstruction
- Principal Investigator
  
  山田篤
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Showa University
Molecular mechanisms underlying homeostasis of artiuclar jointPrincipal Investigator
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Single cell analyses of paraspinal ligament-resident cells to reveal pathogenesis of OPLL
- Principal Investigator
  
  Oshima Yasushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Functional analysis of lubricin as an signaling molecule in regulation and maintenance of the superficial zone of the joint
- Principal Investigator
  
  Uehara Kosuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Integrated Regulation of Articular Cartilage by Runx2 and Runx3
- Principal Investigator
  
  Taniguchi Yuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
AI-assisted diagnostic system for osteoporosis
- Principal Investigator
  
  Moro Toru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Runx2,3による関節軟骨の統合的制御機構の解明
- Principal Investigator
  
  相馬一仁
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Establishment of an integrated locomotive science including dynamics of bone-articular cells and regulation by immune system
- Principal Investigator
  
  Tanaka Sakae
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section I
- Research Institution
  The University of Tokyo
Elucidation of articular joint homeostasis regulated by the cellular network in the synovium
- Principal Investigator
  
  Tanaka Sakae
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Mechanism of bone and cartilage proliferation by a novel bone elongation factor FAM111A
- Principal Investigator
  
  Kitanaka Sachiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying homeostasis of artiuclar joint by oxygen and two HIFs
- Principal Investigator
  
  Mori Daisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Development of induced Drug-Cells for treating Arthritis (DCA) using human ES cells for osteoarthritisPrincipal Investigator
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Regulation of bone remodeling by reactive sulfur species, the novel signal molecules
- Principal Investigator
  
  Kamijo Ryutaro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Showa University
The role of Prg4 in joint development and homeostasisPrincipal Investigator
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Prevention of Adhesion formation of tendon with Oligo-Tetra-PEG gel
- Principal Investigator
  
  Morizaki Yutaka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Development of bone and cartilage implant using collagen 3D printer
- Principal Investigator
  
  Taketomi Shuji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Molecular Mechanisms of How Mechanical Stress Regulates Inflammation of Locomotive Organs
- Principal Investigator
  
  Sawada Yasuhiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Possible novel therapy of degenerated intervertebral disc by ADAMTS10
- Principal Investigator
  
  Taniguchi Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying anti-inflammatory and cartilage protective roles of HIF-1alpha
- Principal Investigator
  
  Okada Keita
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Mechano-sensor TRPV2 is involved in lubricin induction and suppression of ectopic endochondral ossification in articular joints
- Principal Investigator
  
  Kawaguchi Kohei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Screening for anti-arthralgic molecules derived from musclePrincipal Investigator
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Regulation of Articular Chondrocyte DifferentiationPrincipal Investigator
- Principal Investigator
  
  Saito Taku
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Establishment of the protocol for induction and maturation of human induced pluripotent stem cells into meniscus
- Principal Investigator
  
  Yamagami Ryota
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Function of RSPO2 in progerssion of OPLL
- Principal Investigator
  
  Matsubayashi Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Elucidation of biomechanology of intervertebral disc degenration
- Principal Investigator
  
  Anno Masato
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Investigation of cartilage homeostasis and molecular biology by comparison of ankle and knee joint
- Principal Investigator
  
  Matsumoto Takumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Gait analyses of osteoarthritis model mice for joint pain assessmentPrincipal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Development of chondrocyte differentiation method from human iPS cellsPrincipal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Molecular mechanisms of osteoarthritis regulation by Tace signaling
- Principal Investigator
  
  INUI Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Roles of Runx2 and Runx3 in cartilage degeneration
- Principal Investigator
  
  TAKESHITA Katsushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Jichi Medical University
  The University of Tokyo
変形性関節症治療への応用を目指したS100A1、S100Bの機能解析
- Principal Investigator
  
  田中滋之
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Analyses of mechano-sensing pathways in chondrocytes using cyclic hydroctatic pressure modelPrincipal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Analyses of Notch signaling pathway in osteoarthritis
- Principal Investigator
  
  TAKETOMI Shuji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Function of ZNF449 in chondryocyte and mesenchymal tissues
- Principal Investigator
  
  NISHIDA Masahiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Establishment of chondrocyte induction from iPS cells using a fluorescent reporter system.Principal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Research of HIF function in pathophysiology and therapeutics of osteoarthritisPrincipal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Strategic research for elucidation of molecular pathophysiology and identification of therapeutic target of lumbar spondylosis
- Principal Investigator
  
  KAWAGUCHI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
脂質代謝調節因子アディポカインによる軟骨代謝調節機構の検討
- Principal Investigator
  
  廣田仁聡
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Development of novel osteoanabolic agents by selective inhibition of Gq signal in osteoblasts
- Principal Investigator
  
  OGATA Naoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
運動器再生医療を目指した多能性幹細胞から間葉系細胞への分化誘導シグナルの探索
- Principal Investigator
  
  中村耕三
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Research of transcriptional regulation by HIF2A during chondrocyte generation and differentiation.Principal Investigator
- Principal Investigator
  
  SAITO Taku
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
The integrated study for molecular backgrounds and therapeutic targets of osteoarthritis : The ROAD project.
- Principal Investigator
  
  NAKAMURA Kozo
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  国立障害者リハビリテーションセンター(研究所)
  The University of Tokyo
Where is the cause of Bartter's syndrome in the kidney?
- Principal Investigator
  
  WATANABE Sumiyo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Research of the Molecular Network Regulating Endochondral Ossification
- Principal Investigator
  
  KAWAGUCHI Hiroshi
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo

[Book] 関節軟骨のメカノバイオロジ2020
- Author(s)
  齋藤琢
- Total Pages
  6
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-19K22677
[Book] 関節軟骨のメカノバイオロジー2020
- Author(s)
  齋藤琢
- Total Pages
  6
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-20K09428
[Book] 関節軟骨のメカノバイオロジー2020
- Author(s)
  齋藤琢
- Total Pages
  6
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-19K09568
[Book] Elsevier. Chapter “NF-kappaB and HIF Signaling in Osteoarthritis”2020
- Author(s)
  Saito T
- Publisher
  Reference Module in Biomedical Research. Encyclopedia of Bone Biology
- Data Source
  KAKENHI-PROJECT-20K09451
[Book] 変形性関節症の分子病態と治療法開発2020
- Author(s)
  齋藤琢
- Total Pages
  5
- Publisher
  日本整形外科学会雑誌
- Data Source
  KAKENHI-PROJECT-19K22677
[Book] 変形性関節症の分子病態と治療法開発2020
- Author(s)
  齋藤琢
- Total Pages
  5
- Publisher
  日本整形外科学会雑誌
- Data Source
  KAKENHI-PROJECT-20K09451
[Book] 変形性関節症の分子病態と治療法開発2020
- Author(s)
  齋藤琢
- Total Pages
  5
- Publisher
  日本整形外科学会雑誌
- Data Source
  KAKENHI-PROJECT-19K09568
[Book] 変形性関節症の分子病態と治療法開発2020
- Author(s)
  齋藤琢
- Total Pages
  5
- Publisher
  日本整形外科学会雑誌
- Data Source
  KAKENHI-PROJECT-18K09019
[Book] 関節軟骨のメカノバイオロジー2020
- Author(s)
  齋藤琢
- Total Pages
  6
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-18K09019
[Book] 変形性関節症の分子病態と治療法開発2020
- Author(s)
  齋藤琢
- Total Pages
  5
- Publisher
  日本整形外科学会雑誌
- Data Source
  KAKENHI-PROJECT-20K09428
[Book] 実験医学2020
- Author(s)
  齋藤琢
- Total Pages
  6
- Publisher
  関節軟骨のメカノバイオロジー
- Data Source
  KAKENHI-PROJECT-20K09451
[Journal Article] Nutrient-regulated dynamics of chondroprogenitors in the postnatal murine growth plate.2023
- Author(s)
  Oichi T, Kodama J, Wilson K, Tian H, Imamura Kawasawa Y, Usami Y, Oshima Y, Saito T, Tanaka S, Iwamoto M, Otsuru S, Enomoto-Iwamoto M.
- Journal Title
  
  Bone Research
  
  Volume: 11 Issue: 1 Pages: 20-20
- DOI
  10.1038/s41413-023-00258-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09857, KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-22K20967, KAKENHI-PROJECT-21K09243, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-23K27718
[Journal Article] Stem cell-based modeling and single-cell multiomics reveal gene-regulatory mechanisms underlying human skeletal development2023
- Author(s)
  Tani Shoichiro, Okada Hiroyuki, Onodera Shoko, Chijimatsu Ryota, Seki Masahide, Suzuki Yutaka, Xin Xiaonan, Rowe David W., Saito Taku, Tanaka Sakae, Chung Ung-il, Ohba Shinsuke, Hojo Hironori
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 4 Pages: 112276-112276
- DOI
  10.1016/j.celrep.2023.112276
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05318, KAKENHI-PROJECT-22K08773, KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-21J12970, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K21494, KAKENHI-PROJECT-23K27718
[Journal Article] A common variant rs2054564 in ADAMST17 is associated with susceptibility to lumbar spondylosis2023
- Author(s)
  Taniguchi Yuki、Akune Toru、Nishida Nao、Omori Go、HA Kim、Ueno Kazuko、Saito Taku、Oichi Takeshi、Koike Asako、Mabuchi Akihiko、Oka Hiroyuki、Muraki Shigeyuki、Oshima Yasushi、Kawaguchi Hiroshi、Nakamura Kozo、Tokunaga Katsushi、Tanaka Sakae、Yoshimura Noriko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 4900-4900
- DOI
  10.1038/s41598-023-32155-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-21K18291, KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-21K09243, KAKENHI-PROJECT-21K19631, KAKENHI-PROJECT-19H03895, KAKENHI-PROJECT-23K27718
[Journal Article] X線画像データのみから腰椎および大腿骨近位部の骨密度を演算するAI骨粗鬆症診断補助システム2023
- Author(s)
  茂呂徹, 齋藤琢, 田中健之,飯高世, 本多信太郎,吉村典子,田中栄
- Journal Title
  
  整形・災害外科
  
  Volume: 66 Pages: 1135-44
- Data Source
  KAKENHI-PROJECT-20H03798
[Journal Article] Percolation-induced gel-gel phase separation in a dilute polymer network2023
- Author(s)
  Ishikawa Shohei、Iwanaga Yasuhide、Uneyama Takashi、Li Xiang、Hojo Hironori、Fujinaga Ikuo、Katashima Takuya、Saito Taku、Okada Yasushi、Chung Ung-il、Sakumichi Naoyuki、Sakai Takamasa
- Journal Title
  
  Nature Materials
  
  Volume: 22 Issue: 12 Pages: 1564-1570
- DOI
  10.1038/s41563-023-01712-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-21K09243, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21H04688, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-23K22458, KAKENHI-PROJECT-23K24060, KAKENHI-PROJECT-23K27718
[Journal Article] Interstitial-fluid shear stresses induced by vertically oscillating head motion lower blood pressure in hypertensive rats and humans2023
- Author(s)
  Murase Shuhei、Sakitani Naoyoshi、Maekawa Takahiro、Yoshino Daisuke、Takano Kouji、Konno Ayumu、Hirai Hirokazu、Saito Taku、et al
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 7 Issue: 11 Pages: 1350-1373
- DOI
  10.1038/s41551-023-01061-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-23K16632, KAKENHI-PROJECT-22K06454, KAKENHI-PROJECT-21K11330, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-22K19761, KAKENHI-PROJECT-21H04688, KAKENHI-PROJECT-21H04866, KAKENHI-PROJECT-23K24467, KAKENHI-PROJECT-23K27718, KAKENHI-PROJECT-23K27906
[Journal Article] Subcutaneously Transplanted Fresh Cartilage in Allogeneic and Xenogeneic Immunocompetent Mouse2023
- Author(s)
  Uto Sakura、Hikita Atsuhiko、Mori Daisuke、Sakamoto Tomoaki、Yano Fumiko、Ohba Shinsuke、Saito Taku、Takato Tsuyoshi、Hoshi Kazuto
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: 29 Issue: 19-20 Pages: 541-556
- DOI
  10.1089/ten.tea.2023.0052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18325, KAKENHI-PROJECT-21K09243, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21H03136, KAKENHI-PROJECT-23K21494, KAKENHI-PROJECT-23K27718
[Journal Article] Inflammatory Arthritis and Bone Metabolism Regulated by Type 2 Innate and Adaptive Immunity2022
- Author(s)
  Omata Yasunori、Frech Michael、Saito Taku、Schett Georg、Zaiss Mario M.、Tanaka Sakae
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 3 Pages: 1104-1104
- DOI
  10.3390/ijms23031104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-20K09495, KAKENHI-PROJECT-21K09316, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-20H03799
[Journal Article] Identification of ENPP1 Haploinsufficiency in Patients With Diffuse Idiopathic Skeletal Hyperostosis and Early‐Onset Osteoporosis2022
- Author(s)
  Kato Hajime、Ansh Anenya J、Lester Ethan R、Kinoshita Yuka、Hidaka Naoko、Hoshino Yoshitomo、Koga Minae、Taniguchi Yuki、Uchida Taisuke、Yamaguchi Hideki、Niida Yo、Nakazato Masamitsu、Nangaku Masaomi、Makita Noriko、Takamura Toshinari、Saito Taku、Braddock Demetrios T、Ito Nobuaki
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: - Issue: 6 Pages: 1125-1135
- DOI
  10.1002/jbmr.4550
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-19K08996, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-21K09293
[Journal Article] Automatic Detection of Medial and Lateral Compartments from Histological Sections of Mouse Knee Joints Using the Single-Shot Multibox Detector Algorithm2022
- Author(s)
  Mori Yoshifumi、Oichi Takeshi、Enomoto-Iwamoto Motomi、Saito Taku
- Journal Title
  
  CARTILAGE
  
  Volume: 13 Issue: 1
- DOI
  10.1177/19476035221074009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K18540, KAKENHI-PROJECT-20K09495, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-20H03799
[Journal Article] The superficial zone of articular cartilage2022
- Author(s)
  Saito Taku
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1
- DOI
  10.1186/s41232-022-00202-0
- Data Source
  KAKENHI-PROJECT-20H03799
[Journal Article] Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages2022
- Author(s)
  Hojo Hironori, Saito Taku, He Xinjun, Guo Qiuyu, Onodera Shoko, Azuma Toshifumi, Koebis Michinori, Nakao Kazuki, Aiba Atsu, Seki Masahide, Suzuki Yutaka, Okada Hiroyuki, Tanaka Sakae, Chung Ung-il, McMahon Andrew P., Ohba Shinsuke
- Journal Title
  
  Cell Reports
  
  Volume: 40 Issue: 10 Pages: 111315-111315
- DOI
  10.1016/j.celrep.2022.111315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05318, KAKENHI-PROJECT-22K10212, KAKENHI-PROJECT-22K10261, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-21K19589, KAKENHI-PROJECT-22KK0272, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H04952, KAKENHI-PROJECT-20H03885, KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-21K19883, KAKENHI-PROJECT-23K21494, KAKENHI-PROJECT-21H03146
[Journal Article] Transcription Factor Hematopoietically Expressed Homeobox Protein (Hhex) Negatively Regulates Osteoclast Differentiation by Controlling Cyclin‐Dependent Kinase Inhibitors2022
- Author(s)
  Watanabe Hisato、Okada Hiroyuki、Hirose Jun、Omata Yasunori、Matsumoto Takumi、Matsumoto Morio、Nakamura Masaya、Saito Taku、Miyamoto Takeshi、Tanaka Sakae
- Journal Title
  
  JBMR Plus
  
  Volume: 6 Issue: 4
- DOI
  10.1002/jbm4.10608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-20K22973, KAKENHI-PROJECT-21K16703, KAKENHI-PROJECT-21K09316, KAKENHI-PROJECT-21H03057
[Journal Article] TRPV2 is involved in induction of lubricin and suppression of ectopic endochondral ossification in articular joints2021
- Author(s)
  Nakamoto Hideki、Katanosaka Yuki、Chijimatsu Ryota、Mori Daisuke、Xuan Fengjun、Yano Fumiko、Omata Yasunori、Maenohara Yuji、Murahashi Yasutaka、Kawaguchi Kohei、Yamagami Ryota、Inui Hiroshi、Taketomi Shuji、Taniguchi Yuki、Kanagawa Motoi、Naruse Keiji、Tanaka Sakae、Saito Taku
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: - Issue: 8 Pages: 1441-1450
- DOI
  10.1002/art.41684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-21H04960, KAKENHI-PROJECT-20H03799, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-21K09294, KAKENHI-PROJECT-20K20644, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-18K09019
[Journal Article] Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human2021
- Author(s)
  Chijimatsu Ryota、Miwa Satoshi、Okamura Gensuke、Miyahara Junya、Tachibana Naohiro、Ishikura Hisatoshi、Higuchi Junya、Maenohara Yuji、Tsuji Shinsaku、Sameshima Shin、Takagi Kentaro、Nakazato Keiu、Kawaguchi Kohei、Yamagami Ryota、Inui Hiroshi、Taketomi Shuji、Tanaka Sakae、Saito Taku
- Journal Title
  
  Stem Cell Research & Therapy
  
  Volume: 12 Issue: 1
- DOI
  10.1186/s13287-021-02485-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-20H03799, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09495, KAKENHI-PROJECT-21K09294, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-20K18053
[Journal Article] Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage2021
- Author(s)
  Kaneko Taizo、Horiuchi Keisuke、Chijimatsu Ryota、Mori Daisuke、Nagata Kosei、Omata Yasunori、Yano Fumiko、Inui Hiroshi、Moro Toru、Tanaka Sakae、Saito Taku
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: 40 Issue: 2 Pages: 196-207
- DOI
  10.1007/s00774-021-01278-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-20H03799, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09495, KAKENHI-PROJECT-21K19552, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-21K20942
[Journal Article] Stepwise strategy for generating osteoblasts from human pluripotent stem cells under fully defined xeno-free conditions with small-molecule inducers2020
- Author(s)
  Zujur Denise、Kanke Kosuke、Onodera Shoko、Tani Shoichiro、Lai Jenny、Azuma Toshifumi、Xin Xiaonan、Lichtler Alexander C.、Rowe David W.、Saito Taku、Tanaka Sakae、Masaki Hideki、Nakauchi Hiromitsu、Chung Ung-il、Hojo Hironori、Ohba Shinsuke
- Journal Title
  
  Regenerative Therapy
  
  Volume: 14 Pages: 19-31
- DOI
  10.1016/j.reth.2019.12.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11932, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18H03007, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K11898, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19H03833, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Enhancement of chondrogenic differentiation supplemented by a novel small compound for chondrocyte-based tissue engineering2020
- Author(s)
  Hamamoto Shuichi、Chijimatsu Ryota、Shimomura Kazunori、Kobayashi Masato、Jacob George、Yano Fumiko、Saito Taku、Chung Ung-il、Tanaka Sakae、Nakamura Norimasa
- Journal Title
  
  Journal of Experimental Orthopaedics
  
  Volume: 7 Issue: 1 Pages: 446-458
- DOI
  10.1186/s40634-020-00228-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-16H06264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09473, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-20K09405
[Journal Article] Pathomechanism of intervertebral disc degeneration2020
- Author(s)
  Oichi Takeshi、Taniguchi Yuki、Oshima Yasushi、Tanaka Sakae、Saito Taku
- Journal Title
  
  JOR SPINE
  
  Volume: 3 Issue: 1
- DOI
  10.1002/jsp2.1076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling2020
- Author(s)
  Okada Keita、Mori Daisuke、Makii Yuma、Nakamoto Hideki、Murahashi Yasutaka、Yano Fumiko、Chang Song Ho、Taniguchi Yuki、Kobayashi Hiroshi、Semba Hiroaki、Takeda Norihiko、Piao Wen、Hanaoka Kenjiro、Nagano Tetsuo、Tanaka Sakae、Saito Taku
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5425-5425
- DOI
  10.1038/s41598-020-62463-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PUBLICLY-18H04609, KAKENHI-PUBLICLY-19H05414, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-18H02360, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-16H05099, KAKENHI-PROJECT-18K09017, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-20K09405
[Journal Article] Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss2020
- Author(s)
  Omata Yasunori、Frech Michael、Lucas S?bastien、Primbs Tatjana、Knipfer Lisa、Wirtz Stefan、Kadono Yuho、Saito Taku、Tanaka Sakae、Sarter Kerstin、Schett Georg、Zaiss Mario M.
- Journal Title
  
  Bone
  
  Volume: 136 Pages: 115335-115335
- DOI
  10.1016/j.bone.2020.115335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-17K10955
[Journal Article] Ear Cartilage Reconstruction Combining Induced Pluripotent Stem Cell-Derived Cartilage and Three-Dimensional Shape-Memory Scaffold2020
- Author(s)
  Uto Sakura、Hikita Atsuhiko、Sakamoto Tomoaki、Mori Daisuke、Yano Fumiko、Ohba Shinsuke、Saito Taku、Takato Tsuyoshi、Hoshi Kazuto
- Journal Title
  
  Tissue Engineering Part A
  
  Volume: - Issue: 9-10 Pages: 604-617
- DOI
  10.1089/ten.tea.2020.0106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019, KAKENHI-PROJECT-23K21494
[Journal Article] Functional analysis of PTH1R variants found in primary failure of eruption.2020
- Author(s)
  Izumida E, Suzawa T, Miyamoto Y, Yamada A, Takimoto R, Otsu M, Saito T, Yamaguchi T, Nishimura K, Ohtaka M, Nakanishi M, Yoshimura K, Sasa K, Takimoto R, Uyama R, Shirota T, Maki K, Kamijo R.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 99 Issue: 4 Pages: 429-436
- DOI
  10.1177/0022034520901731
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09511, KAKENHI-PROJECT-19K18950, KAKENHI-PROJECT-17K11947, KAKENHI-PROJECT-20K21687, KAKENHI-PROJECT-19H03820, KAKENHI-PROJECT-18K09512, KAKENHI-PROJECT-18K09513, KAKENHI-PROJECT-18K09528, KAKENHI-PROJECT-18K09844, KAKENHI-PROJECT-19K19278, KAKENHI-PROJECT-19K24103, KAKENHI-PROJECT-19H03203, KAKENHI-PROJECT-19K22945
[Journal Article] The small compound, TD-198946, protects against intervertebral degeneration by enhancing glycosaminoglycan synthesis in nucleus pulposus cells2020
- Author(s)
  Kushioka Junichi、Kaito Takashi、Chijimatsu Ryota、Okada Rintaro、Ishiguro Hiroyuki、Bal Zeynep、Kodama Joe、Yano Fumiko、Saito Taku、Chung Ung-il、Tanaka Sakae、Yoshikawa Hideki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 14190-14190
- DOI
  10.1038/s41598-020-71193-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09473, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019
[Journal Article] Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells2020
- Author(s)
  Maenohara Yuji、Chijimatsu Ryota、Tachibana Naohiro、Uehara Kosuke、Xuan Fengjun、Mori Daisuke、Murahashi Yasutaka、Nakamoto Hideki、Oichi Takeshi、Chang Song Ho、Matsumoto Takumi、Omata Yasunori、Yano Fumiko、Tanaka Sakae、Saito Taku
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 36 Issue: 4 Pages: 792-802
- DOI
  10.1002/jbmr.4226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09017, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-21K16690, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019
[Journal Article] Primary culture of mouse adipose and fibrous synovial fibroblasts under normoxic and hypoxic conditions2020
- Author(s)
  SUGIMOTO Hikaru、MURAHASHI Yasutaka、CHIJIMATSU Ryota、MIWA Satoshi、YANO Fumiko、TANAKA Sakae、SAITO Taku
- Journal Title
  
  Biomed. Res.
  
  Volume: 41 Issue: 1 Pages: 43-51
- DOI
  10.2220/biomedres.41.43
- NAID
  130007801491
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2020-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-20K09405
[Journal Article] Associations of clinical outcomes and MRI findings in intra-articular administration of autologous adipose-derived stem cells for knee osteoarthritis2020
- Author(s)
  Higuchi Junya、Yamagami Ryota、Matsumoto Takumi、Terao Tomohiro、Inoue Keita、Tsuji Shinsaku、Maenohara Yuji、Matsuzaki Tokio、Chijimatsu Ryota、Omata Yasunori、Yano Fumiko、Tanaka Sakae、Saito Taku
- Journal Title
  
  Regenerative Therapy
  
  Volume: 14 Pages: 332-340
- DOI
  10.1016/j.reth.2020.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09473, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019
[Journal Article] 2-Methacryloyloxyethyl Phosphorylcholine Polymer Coating Inhibits Bacterial Adhesion and Biofilm Formation on a Suture: An In Vitro and In Vivo Study2020
- Author(s)
  Kaneko Taizo、Saito Taku、Shobuike Takeo、Miyamoto Hiroshi、Matsuda Junpei、Fukazawa Kyoko、Ishihara Kazuhiko、Tanaka Sakae、Moro Toru
- Journal Title
  
  BioMed Research International
  
  Volume: 2020 Issue: 1 Pages: 1-8
- DOI
  10.1155/2020/5639651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-18K09094, KAKENHI-PROJECT-19K22677
[Journal Article] Evidence that TD‐198946 enhances the chondrogenic potential of human synovium‐derived stem cells through the NOTCH3 signaling pathway2020
- Author(s)
  Kobayashi Masato、Chijimatsu Ryota、Hart David A.、Hamamoto Shuichi、Jacob George、Yano Fumiko、Saito Taku、Shimomura Kazunori、Ando Wataru、Chung Ung‐il、Tanaka Sakae、Yoshikawa Hideki、Nakamura Norimasa
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 15 Issue: 2 Pages: 103-115
- DOI
  10.1002/term.3149
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09473, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-20K09405, KAKENHI-PROJECT-18K09019
[Journal Article] Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-52019
- Author(s)
  Miyauchi Aya、Kim-Kaneyama Joo-ri、Lei Xiao-Feng、Chang Song Ho、Saito Taku、Haraguchi Shogo、Miyazaki Takuro、Miyazaki Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 15770-15770
- DOI
  10.1038/s41598-019-52301-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K08590, KAKENHI-PROJECT-19K09033, KAKENHI-PROJECT-19H03110, KAKENHI-PROJECT-17K09869, KAKENHI-PROJECT-17K10713, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway2019
- Author(s)
  Oichi Takeshi、Taniguchi Yuki、Soma Kazuhito、Oshima Yasushi、Yano Fumiko、Mori Yoshifumi、Chijimatsu Ryota、Kim-Kaneyama Joo-ri、Tanaka Sakae、Saito Taku
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 76 Issue: 23 Pages: 4795-4809
- DOI
  10.1007/s00018-019-03188-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10924
[Journal Article] Oral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion2019
- Author(s)
  Murahashi Yasutaka、Yano Fumiko、Chijimatsu Ryota、Nakamoto Hideki、Maenohara Yuji、Amakawa Masahiro、Miyake Yoshihide、Yamanaka Hiroyuki、Iba Kousuke、Yamashita Toshihiko、Tanaka Sakae、Saito Taku
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 20329-20329
- DOI
  10.1038/s41598-019-56861-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Application of Consistent Massage-Like Perturbations on Mouse Calves and Monitoring the Resulting Intramuscular Pressure Changes2019
- Author(s)
  Sakitani Naoyoshi、Maekawa Takahiro、Saitou Kumiko、Suzuki Katsuhiko、Murase Shuhei、Tokunaga Masakuni、Yoshino Daisuke、Sawada Keisuke、Takashima Atsushi、Nagao Motoshi、Ogata Toru、Sawada Yasuhiro
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 151 Issue: 151
- DOI
  10.3791/59475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04088
[Journal Article] Effect of the small compound TD ‐198946 on glycosaminoglycan synthesis and transforming growth factor β3‐associated chondrogenesis of human synovium‐derived stem cells in vitro2019
- Author(s)
  Chijimatsu Ryota、Yano Fumiko、Saito Taku、Kobayashi Masato、Hamamoto Shuichi、Kaito Takashi、Kushioka Junichi、Hart David A.、Chung Ung‐il、Tanaka Sakae、Yoshikawa Hideki、Nakamura Norimasa
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 13 Issue: 3 Pages: 446-458
- DOI
  10.1002/term.2795
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
[Journal Article] Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia2019
- Author(s)
  Inagawa Yuta、Komeno Yukiko、Saito Satoshi、Maenohara Yuji、Yamagishi Tetsuro、Kawashima Hiroyuki、Saito Taku、Abe Keiko、Iihara Kuniko、Hatada Yasumasa、Ryu Tomiko
- Journal Title
  
  Case Reports in Hematology
  
  Volume: 2019 Pages: 1-7
- DOI
  10.1155/2019/1616237
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10960, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds2019
- Author(s)
  Kawata Manabu、Mori Daisuke、Kanke Kosuke、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Yano Fumiko、Masaki Hideki、Otsu Makoto、Nakauchi Hiromitsu、Tanaka Sakae、Saito Taku
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 3 Pages: 530-544
- DOI
  10.1016/j.stemcr.2019.07.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-18K19636, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-18K16645, KAKENHI-PROJECT-17H04403, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects2019
- Author(s)
  Murahashi Yasutaka、Yano Fumiko、Nakamoto Hideki、Maenohara Yuji、Iba Kousuke、Yamashita Toshihiko、Tanaka Sakae、Ishihara Kazuhiko、Okamura Yosuke、Moro Toru、Saito Taku
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 85 Pages: 172-179
- DOI
  10.1016/j.actbio.2018.12.031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-16K10846, KAKENHI-PROJECT-17K19715, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
[Journal Article] Excessive mechanical loading promotes osteoarthritis through the gremlin-1?NF-κB pathway2019
- Author(s)
  Chang Song Ho、Mori Daisuke、Kobayashi Hiroshi、Mori Yoshifumi、Nakamoto Hideki、Okada Keita、Taniguchi Yuki、Sugita Shurei、Yano Fumiko、Chung Ung-il、Kim-Kaneyama Joo-ri、Yanagita Motoko、Economides Aris、Canalis Ernesto、Chen Di、Tanaka Sakae、Saito Taku
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1442-1442
- DOI
  10.1038/s41467-019-09491-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17K16675, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-16K10553, KAKENHI-PROJECT-17K19715, KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-19K22620, KAKENHI-PUBLICLY-18H04673, KAKENHI-PROJECT-17H04187, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
[Journal Article] Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation2019
- Author(s)
  Yano Fumiko、Ohba Shinsuke、Murahashi Yasutaka、Tanaka Sakae、Saito Taku、Chung Ung-il
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 7666-7666
- DOI
  10.1038/s41598-019-43948-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955
[Journal Article] Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone2019
- Author(s)
  Xuan Fengjun、Yano Fumiko、Mori Daisuke、Chijimatsu Ryota、Maenohara Yuji、Nakamoto Hideki、Mori Yoshifumi、Makii Yuma、Oichi Takeshi、Taketo Makoto Mark、Hojo Hironori、Ohba Shinsuke、Chung Ung-il、Tanaka Sakae、Saito Taku
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 21 Issue: 1 Pages: 247-247
- DOI
  10.1186/s13075-019-2041-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-19K22677, KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-20K20473, KAKENHI-PROJECT-17H05106, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10996, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-18H02998, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997
[Journal Article] Local cyclical compression modulates macrophage function in situ and alleviates immobilization-induced muscle atrophy2018
- Author(s)
  1.Saitou K, Tokunaga M, Yoshino D, Sakitani N, Maekawa T, Ryu Y, Nagao M, Nakamoto H, Saito T, Kawanishi N, Suzuki K, Ogata T, Makuuchi M, Takashima A, Sawada K, Kawamura S, Nakazato K, Kouzaki K, Harada I, Ichihara Y, Sawada Y
- Journal Title
  
  Clinical Science
  
  Volume: 132 Issue: 19 Pages: 2147-2161
- DOI
  10.1042/cs20180432
- NAID
  40021950316
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04088, KAKENHI-PROJECT-16K16457
[Journal Article] Alteration of gait parameters in a mouse model of surgically-induced knee osteoarthritis.2018
- Author(s)
  Makii Y, Asaka M, Setogawa S, Fujiki S, Hosaka Y, Yano F, Oka H, Tanaka S, Fukui N, Yanagihara D, and Saito T
- Journal Title
  
  J Orthop Surg (Hong Kong)
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19715
[Journal Article] Alteration of gait parameters in a mouse model of surgically induced knee osteoarthritis.2018
- Author(s)
  Makii Y, Asaka M, Setogawa S, Fujiki S, Hosaka Y, Yano F, Oka H, Tanaka S, Fukui N, Yanagihara D, Saito T.
- Journal Title
  
  J Orthop Surg (Hong Kong).
  
  Volume: 26 Issue: 2 Pages: 2-2
- DOI
  10.1177/2309499018768017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17K11040, KAKENHI-PROJECT-17K10998
[Journal Article] Intra-articular administration of IκBα kinase inhibitor suppresses mouse knee osteoarthritis via downregulation of the NF-κB/HIF-2α axis2018
- Author(s)
  Murahashi Yasutaka、Yano Fumiko、Kobayashi Hiroshi、Makii Yuma、Iba Kousuke、Yamashita Toshihiko、Tanaka Sakae、Saito Taku
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16475-16475
- DOI
  10.1038/s41598-018-34830-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17K19715, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
[Journal Article] Sandwich-type PLLA-nanosheets loaded with BMP-2 induce bone regeneration in critical-sized mouse calvarial defects2017
- Author(s)
  Huang KC, Yano F, Murahashi Y, Takano S, Kitaura Y, Chang SH, Soma K, Ueng SWN, Tanaka S, Ishihara K, Okamura Y, Moro T, Saito T
- Journal Title
  
  Acta Biomater
  
  Volume: 59 Pages: 12-20
- DOI
  10.1016/j.actbio.2017.06.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462
[Journal Article] Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63.2017
- Author(s)
  Taniguchi Y, Kawata M, Chang SH, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills AA, Chung UI, Tanaka S, Kawaguchi H, and Saito T*
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 69 Issue: 3 Pages: 598-609
- DOI
  10.1002/art.39976
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-25713052
[Journal Article] Different regulation of limb development by p63 transcript variants2017
- Author(s)
  Kawata M, Taniguchi Y, Mori D, Yano F, Ohba S, Chung UI, Shimogori T, Mills AA, Tanaka S, Saito T
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 3 Pages: e0174122-e0174122
- DOI
  10.1371/journal.pone.0174122
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-25713052
[Journal Article] Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB2017
- Author(s)
  Saito Taku、Tanaka Sakae
- Journal Title
  
  Arthritis Research & Therapy
  
  Volume: 19 Issue: 1 Pages: 94-94
- DOI
  10.1186/s13075-017-1296-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310
[Journal Article] A Mouse Intervertebral Disc Degeneration Model by Surgically-Induced Instability2017
- Author(s)
  Oichi T, Taniguchi Y, Soma K, Chang SH, Yano F, Tanaka S, Saito T
- Journal Title
  
  Spine
  
  Volume: ― Issue: 10 Pages: 1-1
- DOI
  10.1097/brs.0000000000002427
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10811, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-17K10955
[Journal Article] Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.2016
- Author(s)
  1.Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, Kataoka K, Saito T, Chung UI, Ohba S.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 18743-18743
- DOI
  10.1038/srep18743
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670859, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330
[Journal Article] Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.2016
- Author(s)
  Kobayashi H, Chang S, Mori D, Itoh S, Hirata M, Hosaka Y, Taniguchi Y, Okada K, Mori Y, Yano F, Chung U, Akiyama H, Kawaguchi H, Tanaka S, Saito T.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 13336-13336
- DOI
  10.1038/ncomms13336
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06312, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K18398, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-25713052
[Journal Article] Regulation of mouse chondrocyte differentiation by CCAAT/enhancer-binding proteins 2015
- Author(s)
 Okuma T, Hirata M, Yano F, Mori D, Kawaguchi H, Chung UI, Tanaka S, Saito T
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 1 Pages: 21-29
- DOI
 10.2220/biomedres.36.21
- NAID
 130004903876
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-25713052
[Journal Article] Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells 2015
- Author(s)
 Saito T, Yano F, Mori D, Kawata M, Hoshi K, Takato T, Masaki H, Otsu M, Eto K, Nakauchi H, Chung UI, Tanaka S
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 3 Pages: 179-186
- DOI
 10.2220/biomedres.36.179
- NAID
 130005083858
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K11306, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26463085, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15402, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-25713052
[Journal Article] Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.2015
- Author(s)
  Sugita S, Taketomi S, Saito T, et al.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 10 Pages: 3080-5
- DOI
  10.1073/pnas.1419699112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-25713052, KAKENHI-PROJECT-26713054
[Journal Article] Individual and combining effects of anti-RANKL monoclonal antibody and teriparatide in ovariectomized mice.2015
- Author(s)
  Tokuyama N, Hirose J, Omata Y, Yasui T, Izawa N, Matsumoto T, Masuda H, Ohmiya T,Yasuda H, Saito T, Kadono Y, Tanaka S
- Journal Title
  
  Bone Reports.
  
  Volume: 2 Pages: 1-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293330
[Journal Article] Disease-modifying effects of TD-198946 on progressed osteoarthritis in a mouse model.2014
- Author(s)
  Yano F, Saito T, et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 73 Issue: 11 Pages: 2062-4
- DOI
  10.1136/annrheumdis-2014-205672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-25713052
[Journal Article] Stepwise differentiation of pluripotent stem cells into osteoblasts using four small molecules under serum-free and feeder-free conditions.2014
- Author(s)
  Kanke K, Masaki H, Saito T, Komiyama Y, Hojo H, Nakauchi H, Lichtler AC, Takato T, Chung UI, Ohba S
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 6 Issue: 6 Pages: 751-760
- DOI
  10.1016/j.stemcr.2014.04.016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J01692, KAKENHI-PROJECT-23689079, KAKENHI-PROJECT-24240069, KAKENHI-PROJECT-26293330
[Journal Article] S100A1 and S100B are dispensable for endochondral ossification during skeletal development2014
- Author(s)
  Mori Y, Mori D, Chung UI, Tanaka S, Heierhorst J, Buchou T, Baudier J, Kawaguchi H, Saito T
- Journal Title
  
  Biomed Res
  
  Volume: 35 Pages: 243-50
- NAID
  130004678580
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293330
[Journal Article] Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124 Issue: 2 Pages: 528-542
- DOI
  10.1172/jci68101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-26860474
[Journal Article] S100A1 and S100B are dispensable for endochondral ossification during skeletal development 2014
- Author(s)
 Yoshifumi MORI, Daisuke MORI, Ung-il CHUNG, Sakae TANAKA, Jörg HEIERHORST, Thierry BUCHOU, Jacques BAUDIER, Hiroshi KAWAGUCHI, Taku SAITO
- Journal Title
 
 Biomed. Res.
 
 Volume: 35 Issue: 4 Pages: 243-250
- DOI
 10.2220/biomedres.35.243
- NAID
 130004678580
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
 KAKENHI-PROJECT-25462359
[Journal Article] Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124 Pages: 528-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670634
[Journal Article] Determination of differential gene expression profiles in superficial and deeper zones of mature rat articular cartilage using RNA sequencing of laser microdissected tissue specimens.2014
- Author(s)
  Mori Y, Chung UI, Tanaka S, Saito T
- Journal Title
  
  Biomed Res
  
  Volume: 35 Pages: 263-70
- NAID
  130004678582
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293330
[Journal Article] Positive feedback between NF-κB and TNF-αpromotes leukemia-initiating cell capacity2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M
- Journal Title
  
  J Clin Invest
  
  Volume: 124 Pages: 528-42
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling2014
- Author(s)
  Mori Y, Saito T, Chang SH, Kobayashi H, Ladel CH, Guehring H, Chung UI, Kawaguchi H
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 10192-200
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling2014
- Author(s)
  Mori Y, Saito T, Chang SH, Kobayashi H, Ladel CH, Guehring H, Chung UI, Kawaguchi H
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 10192-200
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling.2014
- Author(s)
  Mori Y, Saito T, Chang SH, Kobayashi H, Ladel CH, Guehring H, Chung UI, Kawaguchi H.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 14 Pages: 10192-200
- DOI
  10.1074/jbc.m113.524090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24390348, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330
[Journal Article] Positive feedback between NF-κB and TNF-αpromotes leukemia-initiating cell capacity2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M
- Journal Title
  
  J Clin Invest
  
  Volume: 124 Pages: 528-42
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination.2014
- Author(s)
  Fujiwara S, Hoshikawa S, Ueno T, Hirata M, Saito T, Ikeda T, Kawaguchi H, Nakamura K, Tanaka S, Ogata T
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 12 Pages: e115400-e115400
- DOI
  10.1371/journal.pone.0115400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-26293330
[Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium.2013
- Author(s)
  Hojo H, Saito T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: E-pub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx12013
- Author(s)
  Yano F, Hojo H, Ohba S, Fukai A, Hosaka Y, Ikeda T, Saito T, Hirata M, Chikuda H, Takato T, Kawaguchi H, Chung UI
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72 Pages: 748-53
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Cell-sheet technology combined with a thienoindazole derivative small comnound TD-198946 for cartilage regeneration2013
- Author(s)
  Yano F, Hojo H, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 22 Pages: 5581-5587
- DOI
  10.1016/j.biomaterials.2013.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04835, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-24240069, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25713052
[Journal Article] Notch signaling in chondrocytes modulatesendochondral ossification and osteoarthritis development2013
- Author(s)
  Hosaka Y, Saito T (equally contributed), et al
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Pages: 1875-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration2013
- Author(s)
  Yano F, Hojo H, Ohba S, Saito T, Honnami M, Mochizuki M, Takato T, Kawaguchi H, Chung UI
- Journal Title
  
  Biomaterials
  
  Volume: 34 Pages: 5581-7
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] □-catenin Regulates PTH/PTHrP Receptor Signals and Chondrocyte Hypertrophy through Binding to Its Intracellular C-terminal Region2013
- Author(s)
  Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H
- Journal Title
  
  Arthritis Rheum
  
  Volume: 65 Pages: 429-35
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development2013
- Author(s)
  Hosaka Y, Saito T, Sugita S, Hikata T, Kobayashi H, Fukai A, Taniguchi Y, Hirata M, Akiyama H, Chung UI, Kawaguchi H
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Pages: 1875-80
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Transcriptional induction of ADAMTS5 by an NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2013
- Author(s)
  Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 28620-9
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium2013
- Author(s)
  Hojo H, Saito T, et al
- Journal Title
  
  J Biol Chem. E-pub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration.2013
- Author(s)
  Yano F, Hojo H, Ohba S, Saito T, Honnami M, Mochizuki M, Takato T, Kawaguchi H, Chung UI.
- Journal Title
  
  Biomaterials
  
  Volume: 34 Pages: 5581-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx12013
- Author(s)
  Yano F, Saito T, et al
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72 Pages: 748-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx12013
- Author(s)
  Yano F, Hojo H, Ohba S, Fukai A, Hosaka Y, Ikeda T, Saito T, Hirata M, Chikuda H, Takato T, Kawaguchi H, Chung UI
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72 Pages: 748-53
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein(BMP) signaling.2013
- Author(s)
  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, and Hoshi K
- Journal Title
  
  J Cell Physiol
  
  Volume: (in press) Issue: 1 Pages: 163-71
- DOI
  10.1002/jcp.24116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249056, KAKENHI-PROJECT-22659365, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23390460, KAKENHI-PROJECT-23592913, KAKENHI-PROJECT-23659938, KAKENHI-PROJECT-24390451, KAKENHI-PROJECT-24593050, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25670847
[Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium.2013
- Author(s)
  Hojo H, Saito T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: E-pub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx1.2013
- Author(s)
  Yano F, Saito T, et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 72 Pages: 748-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Generation of Col2a1-EGFP-iPS cells for monitoring chondrogenic differentiation2013
- Author(s)
  Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] -catenin Regulates PTH/PTHrP Receptor Signals and Chondrocyte Hypertrophy through Binding to Its Intracellular C-terminal Region2013
- Author(s)
  Yano F, Saito T (equally contributed), et al
- Journal Title
  
  Arthritis Rheum
  
  Volume: 65 Pages: 429-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] A novel disease-modifying osteoarthritis drug targeting Runx1.2013
- Author(s)
  Yano F, Saito T, et al.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 72 Pages: 748-753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] β-catenin Regulates PTH/PTHrP Receptor Signals and Chondrocyte Hypertrophy through Binding to Its Intracellular C-terminal Region2013
- Author(s)
  Yano F, Saito T (equally contr ibuted), Ogata N, Yamazawa T, Iino M, Chung UI, Kawaguchi H
- Journal Title
  
  Arthritis Rheum
  
  Volume: 65 Pages: 429-35
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development2013
- Author(s)
  Hosaka Y, Saito T (equally contr ibuted), Sugita S, Hikata T, Kobayashi H, Fukai A, Taniguchi Y, Hirata M, Akiyama H, Chung UI, Kawaguchi H
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Pages: 1875-80
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium2013
- Author(s)
  Hojo H, Ohba S, Taniguchi K, Shirai M, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, Kawaguchi H, Kambara H, Chung UI
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 9924-32
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Transcriptional induction of ADAMTS5 by an NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2013
- Author(s)
  Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 28620-9
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration2013
- Author(s)
  Yano F, Hojo H, Ohba S, Saito T, Honnami M, Mochizuki M, Takato T, Kawaguchi H, Chung UI.
- Journal Title
  
  Biomaterials.
  
  Volume: 34 Pages: 5581-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670634
[Journal Article] Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration2013
- Author(s)
  Yano F, Hojo H, Ohba S, Saito T, Honnami M, Mochizuki M, Takato T, Kawaguchi H, Chung UI
- Journal Title
  
  Biomaterials
  
  Volume: 34 Pages: 5581-7
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.2013
- Author(s)
  Hosaka Y, Saito T (equally contributed), et al.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 110 Pages: 1785-1880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.2013
- Author(s)
  Hosaka Y, Saito T (equally contributed), et al.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 110 Pages: 1875-1880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] -catenin Regulates PTH/PTHrP Receptor Signals and Chondrocyte Hypertrophy through Binding to Its Intracellular C-terminal Region.2013
- Author(s)
  Yano F, Saito T (equally contributed), et al.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 65 Pages: 429-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Generation of Col2a1-EGFP-iPS cells for monitoring chondrogenic differentiation2013
- Author(s)
  Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-24659664
[Journal Article] Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation2013
- Author(s)
  Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
- Journal Title
  
  PLoS One
  
  Volume: 16;8(9) Issue: 9 Pages: e74137-e74137
- DOI
  10.1371/journal.pone.0074137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689052, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
[Journal Article] β-catenin Regulates PTH/PTHrP Receptor Signals and Chondrocyte Hypertrophy through Binding to Its Intracellular C-terminal Region.2013
- Author(s)
  Yano F, Saito T (equally contributed), et al.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 65 Pages: 429-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (NF-κB) family member RelA/p65 in chondrocytes during osteoarthritis development.2013
- Author(s)
  Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Issue: 40 Pages: 28620-9
- DOI
  10.1074/jbc.m113.452169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-24659663, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670634
[Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice.2012
- Author(s)
  Fukai A, Saito T, et al.
- Journal Title
  
  Arthritis Rheum.
  
  Volume: 64 Pages: 198-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification.2012
- Author(s)
  Hojo H, Saito T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 17890-17869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012
- Author(s)
  Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 198-203
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] GSK-3αand GSK-3βproteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation2012
- Author(s)
  Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Woodgett JR, Algül H, Schmid RM, Chung UI, Kawaguchi H
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 29227-36
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification.2012
- Author(s)
  Hojo H, Saito T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 17860-17869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] C/EBPβand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2αas the inducer in chondrocytes2012
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  Hum Mol Genet
  
  Volume: 21 Pages: 1111-23
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation.2012
- Author(s)
  Itoh S, Saito T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 29227-29236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Lack of a chondroprotective effect of cyclooxygenase2 inhibition in a surgically induced model of osteoarthritis in mice2012
- Author(s)
  Fukai A, Saito T, et al
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 198-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice.2012
- Author(s)
  Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H:
- Journal Title
  
  Arthritis Rheum-US
  
  Volume: 64 Pages: 198-203
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice.2012
- Author(s)
  Fukai A, Saito T, et al.
- Journal Title
  
  Arthritis Rheum.
  
  Volume: 64 Pages: 198-2003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] GSK-3α and GSK-3ssproteins are involved in early stages ofchondrocyte differentiation with functional redundancy through RelA protein phosphorylation2012
- Author(s)
  Itoh S, Saito T, et al
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 29227-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Gli1 participates in the hedgehog-mediated specification of the osteoblast lineage during endochondralossification.2012
- Author(s)
  Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, and Ung-il Chung
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 17860-17869
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012
- Author(s)
  Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
- Journal Title
  
  Arthritis Rheum-US
  
  Volume: 64 Pages: 198-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] C/EBPss and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes2012
- Author(s)
  Hirata M, Saito T, et al
- Journal Title
  
  Hum Mol Genet
  
  Volume: 21 Pages: 1111-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.2012
- Author(s)
  Hirata M, Saito T, et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 21 Pages: 1111-1123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] C/EBP-βand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2αas the inducer in chondrocytes2012
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
- Journal Title
  
  Hum Mol Genet
  
  Volume: 21 Pages: 1111-1123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] GSK-3α and GSK-3β are involved in early stages of chondrocyte differentiation with functional redundancy through RelA phosphorylation.2012
- Author(s)
  Itoh S, Saito T, Hirata M, Ushita M, Ikeda T, Woodgett JR, Algul H, Schmid RM, Chung UI, and Kawaguchi H
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 29227-29236
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes2012
- Author(s)
  Hirata M, Saito T, et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 21 Pages: 1111-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.2012
- Author(s)
  Hirata M, Saito T, et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 21 Pages: 11111-11123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification2012
- Author(s)
  Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 17860-9
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] C/EBP-β and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as theinducer in chondrocytes.2012
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
- Journal Title
  
  Hum Mol Genet
  
  Volume: 21 Pages: 1111-1123
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes2012
- Author(s)
  Hirata M, Saito T, et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 21 Pages: 1111-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation.2012
- Author(s)
  Itoh S, Saito T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 29227-29236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification2012
- Author(s)
  Hojo H, Saito T, et al
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 17860-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659704
[Journal Article] Transcriptional regulation of osteoarthritis2011
- Author(s)
  Saito T, et al.
- Journal Title
  
  Clin Calcium
  
  Volume: 21 Pages: 853-9
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair.2011
- Author(s)
  Ishiyama N, Saito T, et al.
- Journal Title
  
  J Bone Joint Surg Am
  
  Volume: 93 Pages: 142-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Reduction of peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair.2011
- Author(s)
  Ishiyama N, Moro T, Ohe T, Miura T, Ishihara K, Konno T, Ohyama T, Yoshikawa M, Kyomoto M, Saito T, Nakamura K, Kawaguchi H.
- Journal Title
  
  J Bone Joint Surg Am. 93
  
  Pages: 142-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Reduction of peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair2011
- Author(s)
  Ishiyama N, Moro T, Ohe T, Miura T, Ishihara K, Konno T, Ohyama T, Yoshikawa M, Kyomoto M, Saito T, Nakamura K, Kawaguchi H
- Journal Title
  
  J Bone J oint Surg Am
  
  Volume: 93 Pages: 142-9
- Data Source
  KAKENHI-PROJECT-23689065
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010
- Author(s)
  Saito T, Kawaguchi H, et al.
- Journal Title
  
  Nat Med.
  
  Volume: 16 Pages: 678-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010
- Author(s)
  Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, et.al.
- Journal Title
  
  Arthritis Rheum. 62(3)
  
  Pages: 826-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development.2010
- Author(s)
  Saito T, et al.
- Journal Title
  
  Nature Med
  
  Volume: 16 Pages: 678-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010
- Author(s)
  Fukai A, Saito T, et al.
- Journal Title
  
  Arthritis Rheum. 62
  
  Pages: 826-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] HIF-2α as a possible therapeutic target of osteoarthritis.2010
- Author(s)
  Saito T, et al.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 18 Pages: 1552-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010
- Author(s)
  Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N
- Journal Title
  
  J Cell Biochem 109
  
  Pages: 755-763
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions.2010
- Author(s)
  Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa A, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum. 62
  
  Pages: 826-836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010
- Author(s)
  Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H.
- Journal Title
  
  Nat Med. 16
  
  Pages: 678-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2αduring skeletal growth and osteoarthritis development2010
- Author(s)
  Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, and Kawaguchi H
- Journal Title
  
  Nat Med
  
  Volume: 16 Pages: 678-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010
- Author(s)
  Saito T, et al.
- Journal Title
  
  Nat Med
  
  Volume: 16 Pages: 678-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] HIF-2α as a possible therapeutic target of osteoarthritis.2010
- Author(s)
  Saito T, Kawaguchi H.
- Journal Title
  
  Osteoarthritis Cartilage. 18
  
  Pages: 1552-1526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development2010
- Author(s)
  Saito T, et.al.
- Journal Title
  
  Nat Med. 16(6)(Epub)
  
  Pages: 678-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Aktl in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010
- Author(s)
  Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa A, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum 62(3)
  
  Pages: 826-36
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] GRIP1 enhances estrogen receptor alpha-dependent extracellular matrix gene expression in chondrogenic cells.2010
- Author(s)
  Kato M, Takaishi H, Yoda M, Tohmonda T, Takito J, Fujita N, Hosogane N, Horiuchi K, Kimura T, Okada Y, Saito T, Kawaguchi H, Kikuchi T, Matsumoto M, Toyama Y, Chiba K.
- Journal Title
  
  Osteoarthritis Cartilage. 18
  
  Pages: 934-941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] GRIP1 Enhances Estrogen Receptor alpha-dependent Extracellular Matrix Gene Expression in Chondrogenic Cells2010
- Author(s)
  Kato M, Saito T, et al.
- Journal Title
  
  Osteoarthritis Cartilage. (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010
- Author(s)
  Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N.
- Journal Title
  
  J Cell Biochem. 109(4)
  
  Pages: 755-63
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.2010
- Author(s)
  Saito T, Nakamura K, et al.
- Journal Title
  
  Nat Med
  
  Volume: 16 Pages: 678-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659347
[Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010
- Author(s)
  Shinoda Y, Saito T, et al.
- Journal Title
  
  J Cell Biochem. 109
  
  Pages: 755-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells2010
- Author(s)
  Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, et.al.
- Journal Title
  
  J Cell Biochem. 109(4)
  
  Pages: 755-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] GRIP1 enhances estrogen receptor alpha-dependent extracellular matrix gene expression in chondrogenic cells.2010
- Author(s)
  Kato M, Saito T, et al.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 18 Pages: 934-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010
- Author(s)
  Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
- Journal Title
  
  Arthritis Rheum
  
  Volume: 62 Pages: 826-836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells.2010
- Author(s)
  Shinoda Y, Kawaguchi H, Higashikawa A, Hirata M, Miura T, Saito T, Nakamura K, Chung UI, Ogata N.
- Journal Title
  
  J Cell Biochem. 109
  
  Pages: 755-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010
- Author(s)
  Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  Arthritis Rheum 62
  
  Pages: 826-836
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development.2010
- Author(s)
  Saito T, et al
- Journal Title
  
  Nat Med
  
  Volume: 16 Pages: 678-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591677
[Journal Article] HIF-2α as a possible therapeutic target of osteoarthritis.2010
- Author(s)
  Saito T, et al.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 18 Pages: 1552-1556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009
- Author(s)
  Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  Arthritis Rheum 60
  
  Pages: 166-178
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor.2009
- Author(s)
  Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum. 60
  
  Pages: 3314-3323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells2009
- Author(s)
  Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, Kawaguchi H
- Journal Title
  
  Osteoarthritis Cartilage 17
  
  Pages: 1065-1075
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009
- Author(s)
  Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum. 60(11)
  
  Pages: 3314-23
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009
- Author(s)
  Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, and Kawaguchi H
- Journal Title
  
  Arthritis Rheum
  
  Volume: 60 Pages: 166-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009
- Author(s)
  Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum 60(1)
  
  Pages: 166-78
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009
- Author(s)
  Higashikawa A, Saito T, Ikeda T, et.al.
- Journal Title
  
  Arthritis Rheum. 60(1)
  
  Pages: 166-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009
- Author(s)
  Kan A, Saito T, et al.
- Journal Title
  
  Arthritis Rheum. 60
  
  Pages: 3314-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells.2009
- Author(s)
  Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, Kawaguchi H.
- Journal Title
  
  Osteoarthritis Cartilage. 17
  
  Pages: 1065-1075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene.2009
- Author(s)
  Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Hirata M, Oshima Y, Ohba S, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum. 60
  
  Pages: 166-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009
- Author(s)
  Kan A, Ikeda T, Saito T, et.al.
- Journal Title
  
  Arthritis Rheum. 60(11)
  
  Pages: 3314-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor2009
- Author(s)
  Kan A, Ikeda T, Saito T, Yano F, Fukai A, Ogata N, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  Arthritis Rheum 60
  
  Pages: 3314-3323
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009
- Author(s)
 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
 
 PLoS ONE 4
- Data Source
 KAKENHI-PROJECT-19109007
[Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, et.al.
- Journal Title
  
  PLoS One. 4(2)(Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] C/EBPβpromotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009
- Author(s)
 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
- Journal Title
 
 PLoS ONE
 
 Volume: 4
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19109007
[Journal Article] C/EBPbeta promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57.2009
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  PLoS ONE. 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  PLoS One. 4(2)
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator.2008
- Author(s)
  Tamiya H, Ikeda T, Jeong JH, Saito T, Yano F, Jung YK, Ohba S, Kawaguchi H, Chung UI, Choi JY.
- Journal Title
  
  Gene. 416
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008
- Author(s)
  Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  J Clin Invest. 118(7)
  
  Pages: 2506-15
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.2008
- Author(s)
  Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  J Clin Invest. 118
  
  Pages: 2506-2515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008
- Author(s)
  Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, et.al.
- Journal Title
  
  J Clin Invest. 118(7), Erratum in 118(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator2008
- Author(s)
  Tamiya H, Ikeda T, Jeong JH, Saito T, et.al.
- Journal Title
  
  Gene. 416(1-2)(Epub)
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcriptional activator2008
- Author(s)
  Tamiya H, Ikeda T, Jung JH, Saito T, Jung YK, Kawaguchi H, Ohba S, Chung UI, Choi JY
- Journal Title
  
  Gene 416
  
  Pages: 53-60
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008
- Author(s)
  Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  J Clin Invest 118
  
  Pages: 2506-2515
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008
- Author(s)
  Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI
- Journal Title
  
  Dev Cell 14
  
  Pages: 689-699
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Patchedl haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008
- Author(s)
  Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI.
- Journal Title
  
  Dev Cell. 14(5)
  
  Pages: 689-99
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.2008
- Author(s)
  Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI.
- Journal Title
  
  Dev Cell. 14
  
  Pages: 689-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689028
[Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008
- Author(s)
  Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, et.al.
- Journal Title
  
  Dev Cell. 14(5)
  
  Pages: 689-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] S100A1 and B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007
- Author(s)
  Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Journal Title
  
  EMBO Rep 8
  
  Pages: 504-509
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007
- Author(s)
  Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, et.al.
- Journal Title
  
  PLoS One. 2(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007
- Author(s)
  Saito T, Ikeda T, et.al.
- Journal Title
  
  EMBO Rep. 8(5)(Epub)
  
  Pages: 504-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007
- Author(s)
  Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  EMBO Rep. 8(5)
  
  Pages: 504-9
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Identification and characterization of the human SOX6 promoter2007
- Author(s)
  Ikeda T, Saito T, et.al.
- Journal Title
  
  Biochem Biophys Res Commun. 357(2)(Epub)
  
  Pages: 383-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] SIOOAI and B,transcriPtional targets of SOX trio,inhibitterminal differentiation of chondrocytes2007
- Author(s)
  Taku Saito, et. al.
- Journal Title
  
  EMBO Rep 8
  
  Pages: 504-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Identification and characterization of the human SOX6 promoter2007
- Author(s)
  Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI
- Journal Title
  
  Biochem Biophys Res Commun 357
  
  Pages: 383-390
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Aktl in osteoblasts and osteoclasts controls bone remodeling2007
- Author(s)
  Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  PLoS One. 2(10)
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] S100A1 and B, transcripitional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007
- Author(s)
  Taku Saito, et. al.
- Journal Title
  
  EMBO Rep 8
  
  Pages: 504-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19109007
[Journal Article] Carminerin contributes to chondrocyte calcification during endochondral ossification2006
- Author(s)
  Yamada T, Kawano H, Koshizuka Y, Fukuda T, Yoshimura K, Kamekura S, Saito T, Ikeda T, Kawasaki Y, Azuma Y, Ikegawa S, Hoshi K, Chung UI, Nakamura K, Kato S, Kawaguchi H.
- Journal Title
  
  Nat Med. 12(6)
  
  Pages: 665-70
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
- Author(s)
  Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H.
- Journal Title
  
  Nat Med (in press)
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] β-catenin regulates PTH/PTHrP receptor signals and chondrocyte hypertrophy through binding to its intracellular C-terminal region.
- Author(s)
  Yano F, Saito T, Ogata N, Yamazawa T, Iino M, Chung UI, and Kawaguchi H
- Journal Title
  
  Arthritis Rheum-US
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] S100A1 and B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes.
- Author(s)
  Taku Saito, et al.
- Journal Title
  
  EMBO Rep (印刷中)
- Data Source
  KAKENHI-PROJECT-18209047
[Journal Article] A novel disease-modifying osteoarthritis drug candidate targeting Runx1.
- Author(s)
  Yano F, Hojo H, Ohba S, Fukai A, Hosaka Y, Ikeda T, Saito T, Hirata M, Chikuda H,Takato T, Kawaguchi H, and Chung UI
- Journal Title
  
  Ann Rheum Dis(in press).
- Data Source
  KAKENHI-PROJECT-22249056
[Journal Article] Transcriptional regulation of endochondral ossification by HIF2A during skeletal growth and osteoarthritis development
- Author(s)
  Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
- Journal Title
  
  Nature Med (in press)
- Data Source
  KAKENHI-PROJECT-19109007
[Patent] 軟骨細胞の製造方法2016
- Inventor(s)
  齋藤琢、ほか
- Industrial Property Rights Holder
  齋藤琢、ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-163872
- Filing Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 1枚の腰椎正面X線像のみから大腿骨近位部の骨密度を演算するAI骨粗鬆症診断補助システム2023
- Author(s)
  茂呂徹, 齋藤琢, 岡敬之, 田中健之, 大野久美子, 石倉久年, 飯高世子, 浅井真, 神永尚人, 吉村典子, 田中栄
- Organizer
  東日本整形災害外科学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 1枚の腰椎正面X線像のみから腰椎BMDを演算するAI骨粗鬆症診断補助システムのスクリーニング・診断精度評価2023
- Author(s)
  茂呂徹, 齋藤琢, 岡敬之, 田中健之, 大野久美子, 石倉久年, 飯高世子, 神永尚人, 吉村典子, 田中栄
- Organizer
  日本骨形態計測学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 腰椎/胸部正面X線画像から腰椎および大腿骨近位部の骨密度推定値を演算するAI骨粗鬆症診断補助システム2023
- Author(s)
  茂呂徹, 齋藤琢, 吉村典子, 岡敬之, 小俣康徳, 田中健之, 大野久美子, 石倉久年, 飯高世子, 神永尚人, 佐藤雅史, 伊東伸朗, 田辺真彦, 藤尾圭志, 小川純人, 田中栄
- Organizer
  第25回日本骨粗鬆症学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 廃用関節では滑膜マクロファージおよび滑膜線維芽細胞の特異的クラスターが軟骨変性に寄与する2023
- Author(s)
  寺島明日香、石倉久年、宮原潤也、岡田寛之、矢野文子、小俣康徳、田中栄、齋藤琢
- Organizer
  第8回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K09300
[Presentation] 軟骨表層細胞におけるNotchシグナルの軟骨恒常性維持機構の解明2023
- Author(s)
  岩永康秀, 齋藤琢, 田中栄
- Organizer
  第13回Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-23K27718
[Presentation] シンポジウム2　次世代CAOSにおけるAIの台頭とその役割　～Next Standardの確立に向けて～　胸部/腰椎正面X線画像のみから骨密度を演算するAI骨粗鬆症診断補助システムの開発.2023
- Author(s)
  茂呂徹, 齋藤琢, 吉村典子, 田中健之, 大野久美子, 石倉久年,飯高世子, 浅井真, 神永尚人, 田中栄
- Organizer
  第17回日本COAS研究会.
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 1枚の腰椎正面X線画像のみから腰椎及び大腿骨近位部の骨密度推定値を演算するAI骨粗鬆症診断補助システム2023
- Author(s)
  茂呂徹, 吉村典子, 齋藤琢, 大野久美子, 飯高世子, 小川純人, 田中栄
- Organizer
  日本老年病学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] Runx2とRunx3は手術誘導された変形性関節症において関節軟骨に異なる役割を果たす2023
- Author(s)
  永田向生, 齋藤琢, 北條宏徳, 矢野文子, 岡田寛之, 大庭伸介, 鄭雄一, 田中栄
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27718
[Presentation] 幹細胞による関節治療の分子メカニズム2023
- Author(s)
  笠井太郎, 齋藤琢
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K27718
[Presentation] 胸部正面X線画像のみから腰椎/大腿骨近位部の骨密度推定値を演算するAI骨粗鬆症診断補助システム2023
- Author(s)
  茂呂徹, 齋藤琢, 岡敬之, 田中健之, 大野久美子, 石倉久年, 飯高世子, 浅井真, 神永尚人, 吉村典子, 田中栄
- Organizer
  西日本整形災害外科学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 1枚の腰椎正面X線像のみから腰椎の骨密度を演算するAI骨粗鬆症診断補助システムのスクリーニング・診断精度評価2023
- Author(s)
  茂呂徹, 齋藤琢, 岡敬之, 田中健之, 大野久美子, 石倉久年, 飯高世子, 浅井真, 神永尚人, 吉村典子, 田中栄
- Organizer
  第38回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] Baricitinibは後根神経節細胞におけるIL-6 AmpとCSF-1の発現を抑制することによって関節炎モデルマウスの神経障害性疼痛を改善する.2023
- Author(s)
  真壁健太, 小俣康徳, 岡田寛之, 千々松良太, 寺島明日香, 矢野文子, 田中栄, 齋藤琢.
- Organizer
  第10回 JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-21K09294
[Presentation] 血友病性関節症の病態解明2023
- Author(s)
  寺島明日香、森大典、大野久美子、竹谷英之、齋藤琢
- Organizer
  2023年度東京骨関節フォーラム
- Data Source
  KAKENHI-PROJECT-22K09300
[Presentation] 胸部正面X線画像のみから腰椎/大腿骨近位部の骨密度推定値を演算するAI骨粗鬆症診断補助システム2023
- Author(s)
  茂呂徹, 齋藤琢, 田中健之, 大野久美子, 飯高世子, 石倉久年, 浅井真, 神永尚人, 小川純人, 吉村典子, 田中栄
- Organizer
  日本整形外科学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 廃用関節では滑膜マクロファージおよび滑膜線維芽細胞の特異的クラスターが軟骨変性に寄与する2022
- Author(s)
  石倉久年、齋藤琢、他
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] 脂肪幹細胞による変形性関節症の病態制御機構2022
- Author(s)
  樋口淳也、田中栄、齋藤琢、他
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] Transient Receptor Potential Vanilloid Channel 2は関節軟骨においてルブリシンを誘導し異所性骨化を抑制する2022
- Author(s)
  中元秀樹、田中栄、齋藤琢、他
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] パネルディスカッション2：運動器疾患におけるAI最前線　腰椎・胸部正面X線画像を用いたAI骨粗鬆症診断補助システム.2022
- Author(s)
  茂呂徹, 吉村典子, 齋藤琢, 飯高世子, 小川純人, 田中栄
- Organizer
  第40回日本骨代謝学会学術集会.
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 腰椎・胸部正面X線画像を用いたAI骨粗鬆症診断補助システム　骨密度推定・スクリーニング精度に関する検討.2022
- Author(s)
  茂呂徹, 齋藤琢, 田中健之, 橋倉一彰, 浅井真, 大野久美子, 小川純人, 田中栄
- Organizer
  第95回日本整形外科学会学術総会.
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 2種類の低分子化合物による、簡便で高効率なヒト多能性幹細胞の軟骨細胞への分化誘導法2022
- Author(s)
  河田学、田中栄、齋藤琢、他
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 廃用関節では滑膜マクロファージおよび滑膜線維芽細胞の特異的クラスターが軟骨変性に寄与する2022
- Author(s)
  石倉久年、田中栄、齋藤琢、他
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 廃用関節では滑膜マクロファージおよび滑膜線維芽細胞の特異的クラスターが軟骨変性に寄与する2022
- Author(s)
  石倉久年、齋藤琢、他
- Organizer
  第61回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] トランスレーショナルリサーチ４　腰椎・胸部正面X線画像から骨密度推定値を出力するAI骨粗鬆症診断補助システム.2022
- Author(s)
  茂呂徹, 齋藤琢, 吉村典子, 田中健之, 大野久美子, 石倉久年, 飯高世子, 浅井真, 神永尚人, 小川純人, 田中栄
- Organizer
  第37回日本整形外科学会基礎学術集会.
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 廃用関節では滑膜マクロファージおよび滑膜線維芽細胞の特異的クラスターが軟骨変性に寄与する2022
- Author(s)
  石倉久年、齋藤琢、他
- Organizer
  第34回軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] Rspo2/Prg4陽性細胞は異所性軟骨内骨化を抑制して腱・靱帯の恒常性に寄与する2022
- Author(s)
  立花直寛、田中栄、齋藤琢、他
- Organizer
  第34回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 変形性関節症における骨・軟骨連関2021
- Author(s)
  齋藤琢
- Organizer
  第94回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 脂肪由来幹細胞を用いた変形性関節症治療2021
- Author(s)
  齋藤琢
- Organizer
  第94回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19552
[Presentation] 脂肪幹細胞による変形性関節症の病態制御機構、第39回日本骨代謝学会2021
- Author(s)
  樋口淳也、田中栄、齋藤琢、他
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 変形性関節症における骨・軟骨連関2021
- Author(s)
  齋藤琢
- Organizer
  第94回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19552
[Presentation] 変形性関節症における骨・軟骨連関2021
- Author(s)
  齋藤琢
- Organizer
  第94回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] 関節軟骨の維持機構2021
- Author(s)
  齋藤琢
- Organizer
  第42回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 変形性関節症の分子機序2021
- Author(s)
  齋藤琢
- Organizer
  第49回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] scRNA-seqを用いた頚椎後縦靭帯骨化症の発症における疾患感受性遺伝子RSPO2の役割の検証2021
- Author(s)
  立花直寛、田中栄、千々松良太、齋藤琢、他
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 変形性関節症の分子病態からみたPRP/APSと幹細胞治療2021
- Author(s)
  齋藤琢
- Organizer
  第36回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] ADAM17/TACE accerates osteoarthritis develpoment through EGFR signaling and TNF pathways2021
- Author(s)
  Kaneko T, Yano F, Chijimatsu R, Tanaka S, Saito T
- Organizer
  2021 Auunal Meeting of the Orthopaedic Resarch Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] Motion is essential to maintain the synovial condition and joint homeostasis.2021
- Author(s)
  Ishikura H, Chijimatsu R, Okada H, Suzuki Y, Miyahara J, Omata Y, Yano F, Tanaka S, Saito T
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] Tetra-Peg gelを用いた損傷腱のintrinsic healingの検討2021
- Author(s)
  岩永康秀、森崎裕、斎藤琢、酒井崇匡
- Organizer
  日本整形外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09243
[Presentation] 脂肪由来幹細胞を用いた変形性関節症治療2021
- Author(s)
  齋藤琢
- Organizer
  第94回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] ルブリシンは関節軟骨最表層細胞の分化を抑制し軟骨のホメオスタシスを維持している2021
- Author(s)
  前之原悠司　千々松良太　中元秀樹　矢野文子　齋藤琢
- Organizer
  第33回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] 関節運動は滑膜を介した関節恒常性維持機構に必須である2021
- Author(s)
  石倉久年、田中栄、齋藤琢、他
- Organizer
  第39回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 腰椎正面X線画像を用いたAI骨粗鬆症診断補助システムの骨密度推定・スクリーニング精度に関する検討－ROAD study第3回調査結果を用いた検討2021
- Author(s)
  茂呂徹, 吉村典子, 飯高世子, 齋藤琢, 田中健之, 橋倉一彰, 大野久美子, 田中栄
- Organizer
  第23回日本骨粗鬆症学会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 主題セッション1 「整形外科領域における人工知能の応用」AI骨粗鬆症診断補助システムのスクリーニング精度に関する検討　－腰椎・胸部正面X線画像を用いた骨密度推定2021
- Author(s)
  茂呂徹, 齋藤琢, 浅井真, 橋倉一彰, 大野久美子, 田中栄
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] ADAM17/TACE accerates osteoarthritis develpoment through EGFR signaling and TNF pathways2021
- Author(s)
  Kaneko T, Yano F, Chijimatsu R, Tanaka S, Saito T
- Organizer
  2021 Auunal Meeting of the Orthopaedic Resarch Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] 変形性関節症の分子病態からみたPRP/APSと幹細胞治療2021
- Author(s)
  齋藤琢
- Organizer
  第36回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Motion is essential to maintain the synovial condition and joint homeostasis2021
- Author(s)
  Ishikura H, Tanaka S, Saito T, et al
- Organizer
  ANZBMS 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] AI骨粗鬆症診断補助システムを用いたスクリーニング精度に関する基礎検討　－腰椎正面X線画像を用いた高精度骨密度推定2021
- Author(s)
  茂呂徹, 齋藤琢, 田中健之, 橋倉一彰, 大野久美子, 小川純人, 田中栄
- Organizer
  第94回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] 関節軟骨の維持機構2021
- Author(s)
  齋藤琢
- Organizer
  第42回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03799
[Presentation] 抗コラーゲン抗体関節炎マウスを用いたBaricitinibの疼痛抑制作用の解析2021
- Author(s)
  真壁健太、小俣康徳、淺香明子、柳原大、千々松良太、矢野文子、田中栄、齋藤琢
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09294
[Presentation] Rspo2/Prg4-positive cells contribute ligament/tendon homeostasis through suppression of ectopic endochondral ossification.2021
- Author(s)
  Tachibana N, Chijimatsu R, Okada H, Oichi T, Taniguchi Y, Miyahara J, Ishikura H, Nagata K, Nakamoto H, Kato S, Doi T, Matsubayashi Y, Oshima Y, Omata Y, Yano F, Maeda S, Ikegawa S, Tanaka S, Saito T
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] 関節軟骨の維持機構2021
- Author(s)
  齋藤琢
- Organizer
  第42回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19552
[Presentation] 変形性関節症の分子機序2021
- Author(s)
  齋藤琢
- Organizer
  第49回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19552
[Presentation] ADAM17/TACE accerates osteoarthritis develpoment through EGFR signaling and TNF pathways2021
- Author(s)
  Kaneko T, Yano F, Chijimatsu R, Tanaka S, Saito T
- Organizer
  2021 Auunal Meeting of the Orthopaedic Resarch Societ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] ADAM17/TACE accerates osteoarthritis develpoment through EGFR signaling and TNF pathways2021
- Author(s)
  Kaneko T, Yano F, Chijimatsu R, Tanaka S, Saito T
- Organizer
  2021 Auunal Meeting of the Orthopaedic Resarch Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Motion is essential to maintain the synovial condition and joint homeostasis.2021
- Author(s)
  Ishikura H, Tanaka S, Saito T, et al
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] Motion is essential to maintain synovial condition and joint homeostasis2021
- Author(s)
  石倉久年、千々松良太、岡田寛之、鈴木譲、宮原潤也、小俣康徳、矢野文子、田中栄、斎藤琢
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] Rspo2/Prg4-positive cells contribute ligament/tendon homeostasis through suppression of ectopic endochondral ossification.2021
- Author(s)
  Tachibana N, Tanaka S, Chijimatsu R, Saito T, et al
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] Molecular mechanisms underlying adipose-derived stem cell therapy for osteoarthritis2021
- Author(s)
  Higuchi J, Tanaka S, Saito T, et al
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20473
[Presentation] 変形性関節症の分子機序2021
- Author(s)
  齋藤琢
- Organizer
  第49回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 変形性関節症の分子病態からみたPRP/APSと幹細胞治療2021
- Author(s)
  齋藤琢
- Organizer
  第36回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19552
[Presentation] Notchは最表層細胞の維持を介して関節軟骨の恒常性に貢献する2020
- Author(s)
  岩永康秀、永田向生、千々松良太、矢野文子、田中栄、齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] OAの病態における軟骨と周囲組織との関連2020
- Author(s)
  齋藤琢
- Organizer
  第48回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] 関節軟骨の維持機構2020
- Author(s)
  齋藤琢
- Organizer
  第64回日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] Taceは変形性関節症を促進的に制御する2020
- Author(s)
  金子泰三、千々松良太、矢野文子、堀内圭輔、田中栄、齋藤琢
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] 関節軟骨の維持機構2020
- Author(s)
  齋藤琢
- Organizer
  第64回日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Runx3 は関節軟骨に保護的に作用する2020
- Author(s)
  永田向生、張成虎、矢野文子、、田中栄、齋藤琢
- Organizer
  11th Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Runx3 protects articular cartilage by direct induction of Prg4.2020
- Author(s)
  Kosei Nagata, Taku Saito, Fumiko Yano, Hirnori Hojo, Yasuhide Iwanaga, and Sakae Tanaka.
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] Notchは最表層細胞の維持を介して関節軟骨の恒常性に貢献する2020
- Author(s)
  岩永康秀、永田向生、千々松良太、矢野文子、田中栄、齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] Taceは変形性関節症を促進的に制御する2020
- Author(s)
  金子泰三、千々松良太、矢野文子、堀内圭輔、田中栄、齋藤琢
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] OAの病態における軟骨と周囲組織との関連2020
- Author(s)
  齋藤琢
- Organizer
  第48回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] OAの病態における軟骨と周囲組織との関連2020
- Author(s)
  齋藤琢
- Organizer
  第48回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 関節軟骨の維持機構2020
- Author(s)
  齋藤琢
- Organizer
  第64回日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] TRPV2 protects articular cartilage via lubricin induction2020
- Author(s)
  Nakamoto H, Saito T, et al.
- Organizer
  ORS 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10997
[Presentation] TRPV2 protects articular cartilage via lubricin induction2020
- Author(s)
  Nakamoto H, Saito T, et al.
- Organizer
  ORS 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Notchは最表層細胞の維持を介して関節軟骨の恒常性に貢献する2020
- Author(s)
  岩永康秀、永田向生、千々松良太、矢野文子、田中栄、齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] Runx3 protects articular cartilage by direct induction of Prg42020
- Author(s)
  Kosei Nagata, Taku Saito, Fumiko Yano, Hirnori Hojo, Yasuhide Iwanaga, and Sakae Tanaka.
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 関節軟骨層ごとの主要シグナルの役割2020
- Author(s)
  齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] Taceは変形性関節症を促進的に制御する2020
- Author(s)
  金子泰三、千々松良太、矢野文子、堀内圭輔、田中栄、齋藤琢
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Notchは最表層細胞の維持を介して関節軟骨の恒常性に貢献する2020
- Author(s)
  岩永康秀、永田向生、千々松良太、矢野文子、田中栄、齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] Notch signaling contributes to articular cartilage homeostasis by suppressing differentiation of superficial zone cells2020
- Author(s)
  Iwanaga Y, Nagata K, Yano F, Tanaka S, Saito T
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] Notch signaling contributes to articular cartilage homeostasis by suppressing differentiation of superficial zone cells2020
- Author(s)
  Iwanaga Y, Nagata K, Yano F, Tanaka S, Saito T
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] ADAM17/TACE accerates osteoarthritis develpoment through EGFR signaling and TNF pathway2020
- Author(s)
  Kaneko T, Yano F, Chijimatsu R, Tanaka S, Saito T
- Organizer
  2021 Auunal Meeting of the Orthopaedic Resarch Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] 関節軟骨層ごとの主要シグナルの役割2020
- Author(s)
  齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] OAの病態における軟骨と周囲組織との関連2020
- Author(s)
  齋藤琢
- Organizer
  第48回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] 関節軟骨の維持機構2020
- Author(s)
  齋藤琢
- Organizer
  第64回日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] 関節軟骨の維持機構2020
- Author(s)
  齋藤琢
- Organizer
  第64回日本リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] AIによる骨粗鬆症の早期診断に関する基礎検討―胸部X線画像を用いた骨密度推定.2020
- Author(s)
  茂呂徹, 齋藤琢, 田中健之, 橋倉一彰, 大野久美子, 小川純人, 田中栄
- Organizer
  第22回日本骨粗鬆症学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] Notch signaling contributes to articular cartilage homeostasis by suppressing differentiation of superficial zone cells2020
- Author(s)
  Iwanaga Y, Nagata K, Yano F, Tanaka S, Saito T
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 脂肪幹細胞を用いた変形性膝関節症治療の臨床成績と、治療効果に関係するMRI所見の検討2020
- Author(s)
  樋口淳也, 山神良太, 松本卓巳, 前之原悠司, 寺尾友宏, 井上啓太, 辻晋作, 千々松良太, 小俣康徳, 矢野文子, 田中栄, 齋藤琢
- Organizer
  第19回再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] 脂肪幹細胞を用いた変形性膝関節症治療の臨床成績と、治療効果に関係するMRI所見の検2020
- Author(s)
  樋口淳也, 山神良太, 松本卓巳, 前之原悠司, 寺尾友宏, 井上啓太, 辻晋作, 千々松良太, 小俣康徳, 矢野文子, 田中栄, 齋藤琢
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 関節軟骨層ごとの主要シグナルの役割2020
- Author(s)
  齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] Notchは最表層細胞の維持を介して関節軟骨の恒常性に貢献する2020
- Author(s)
  岩永康秀、永田向生、千々松良太、矢野文子、田中栄、齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Taceは変形性関節症を促進的に制御する2020
- Author(s)
  金子泰三、千々松良太、矢野文子、堀内圭輔、田中栄、齋藤琢
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] OAの病態における軟骨と周囲組織との関連2020
- Author(s)
  齋藤琢
- Organizer
  第48回日本関節病学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] Taceは変形性関節症を促進的に制御する2020
- Author(s)
  金子泰三、千々松良太、矢野文子、堀内圭輔、田中栄、齋藤
- Organizer
  第38回日本骨代謝学会学術集
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] Runx3 protects articular cartilage by direct induction of Prg4.2020
- Author(s)
  Kosei Nagata, Taku Saito, Fumiko Yano, Hirnori Hojo, Yasuhide Iwanaga, and Sakae Tanaka.
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] 関節軟骨層ごとの主要シグナルの役割2020
- Author(s)
  齋藤琢
- Organizer
  第35回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K09019
[Presentation] Notch signaling contributes to articular cartilage homeostasis by suppressing differentiation of superficial zone cells2020
- Author(s)
  Iwanaga Y, Nagata K, Yano F, Tanaka S, Saito T
- Organizer
  米国骨代謝学会ASBMR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09451
[Presentation] Runx3 protects articular cartilage by direct induction of Prg42020
- Author(s)
  Kosei Nagata, Taku Saito, Fumiko Yano, Hirnori Hojo, Yasuhide Iwanaga, and Sakae Tanaka.
- Organizer
  ASBMR 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09428
[Presentation] AIによる骨粗鬆症の早期診断に関する基礎検討―腰椎・膝関節X線画像を用いた骨密度推定.2020
- Author(s)
  茂呂徹, 齋藤琢, 田中健之, 橋倉一彰, 大野久美子, 小川純人, 田中栄
- Organizer
  第22回日本骨粗鬆症学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03798
[Presentation] メカノセンサーTrpv2 はLubricin の誘導を介して関節軟骨を保護する2019
- Author(s)
  中元秀樹、森大典、齋藤琢、他
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 変形性関節症の分子病態と治療法の開発2019
- Author(s)
  齋藤琢
- Organizer
  第68回東日本整形災害外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] 変形性関節症の分子病態と治療法開発2019
- Author(s)
  齋藤琢
- Organizer
  第92回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] メカノセンサーTrpv2 はLubricin の誘導を介して関節軟骨を保護する2019
- Author(s)
  中元秀樹、齋藤琢、他
- Organizer
  第10回 Orthopedic Research Club
- Data Source
  KAKENHI-PROJECT-17K10997
[Presentation] 過剰な力学的負荷による軟骨変性の分子機構2019
- Author(s)
  齋藤琢
- Organizer
  第20回運動器科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10996
[Presentation] 変形性関節症の分子病態と治療法の研究2019
- Author(s)
  齋藤琢
- Organizer
  第26回埼玉骨・関節疾患研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] 過剰な力学的負荷による軟骨変性の分子機構2019
- Author(s)
  齋藤琢
- Organizer
  第20回運動器科学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] 機能未知蛋白FAM111Aによる低身長発症機構の解明.2019
- Author(s)
  田中裕之, 田村麻由子, 藤澤佑介, 寺田有美子, 高橋千恵, 磯島豪, 岡明, 齋藤琢, 北中幸子
- Organizer
  第53回小児内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08246
[Presentation] Taceは変形性関節症を促進的に制御する2019
- Author(s)
  金子泰三、森大典、齋藤琢、他
- Organizer
  第37回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] 変形性関節症の分子病態と治療法の開発2019
- Author(s)
  齋藤琢
- Organizer
  第68回東日本整形災害外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10996
[Presentation] 変形性関節症の分子病態と治療法開発2019
- Author(s)
  齋藤琢
- Organizer
  第92回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10996
[Presentation] 変形性関節症の分子病態と治療法開発2019
- Author(s)
  齋藤琢
- Organizer
  第92回日本整形外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22677
[Presentation] メカノセンサーTrpv2 はLubricin の誘導を介して関節軟骨を保護する2019
- Author(s)
  中元秀樹、齋藤琢、他
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K10997
[Presentation] 変形性関節症の分子病態と治療法の開発2019
- Author(s)
  齋藤琢
- Organizer
  第68回東日本整形災害外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] ルブリシンは関節軟骨最表層細胞の分化を抑制し軟骨のホメオスタシスを維持している2019
- Author(s)
  前之原悠司、森大典、齋藤琢、他
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09568
[Presentation] Runx3は関節軟骨に保護的に作用する2018
- Author(s)
  永田向生、齋藤琢、他
- Organizer
  第36回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] Runx3は関節軟骨に保護的に作用する2018
- Author(s)
  永田向生、齋藤琢、他
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] 体表からの局所的反復性圧迫は身体不活動により促進される単球/マクロファージの活性を抑制し骨格筋の萎縮を緩和する2018
- Author(s)
  澤田泰宏、斎藤久美子、徳永正邦、市原克則、吉野大輔、前川貴郊、緒方徹、長尾元史
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04088
[Presentation] 変形性関節症の分子病態と治療法の研究2018
- Author(s)
  齋藤琢
- Organizer
  第6回軟骨・椎間板研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] 変形性関節症の分子病態と治療法の研究2018
- Author(s)
  齋藤琢
- Organizer
  第33回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] 転写因子HIF-2aは関節軟骨最表層に発現し、関節軟骨に保護的に作用する2017
- Author(s)
  牧井勇磨、齋藤琢、他
- Organizer
  日本骨代謝学会、日本整形外科学会基礎学術集会、日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] β-cateninシグナルは関節軟骨最表層の維持に必須である2017
- Author(s)
  玄峰俊、齋藤琢、他
- Organizer
  日本骨代謝学会、日本整形外科学会基礎学術集会、日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-17H04310
[Presentation] 過剰な力学的ストレスによる関節軟骨異化のメカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第34回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] Regulation of Articular Cartilage Homeostasis and Osteoarthritis Development by the NF-kappaB signaling.2016
- Author(s)
  Taku Saito
- Organizer
  2016 Cold Spring Harbor Asia Conference on Bone & Cartilage
- Place of Presentation
  Suzhou, China
- Year and Date
  2016-10-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] 過剰な力学的ストレス負荷による関節軟骨変性の分子メカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] 過剰な力学的ストレスによる関節軟骨異化のメカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第34回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 変性性関節症の制御メカニズム2016
- Author(s)
  齋藤琢
- Organizer
  Orthopedic Research Club
- Place of Presentation
  木更津
- Year and Date
  2016-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] Perspective of disease-modifying osteoarthritis drugs2016
- Author(s)
  Taku Saito
- Organizer
  第3回アジア太平洋骨代謝学会議
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 過剰な力学的ストレス負荷による関節軟骨変性の分子メカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] Regulation of Articular Cartilage Homeostasis and Osteoarthritis Development by the NF-kappaB signaling.2016
- Author(s)
  Taku Saito
- Organizer
  2016 Cold Spring Harbor Asia Conference on Bone & Cartilage
- Place of Presentation
  Suzhou, China
- Year and Date
  2016-10-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] 転写因子を起点とした変形性関節症のメカニズム2016
- Author(s)
  齋藤琢他
- Organizer
  第29回日本軟骨代謝学会
- Place of Presentation
  広島
- Year and Date
  2016-02-19
- Invited
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] Different regulation of limb development by p63 transcript variants.2016
- Author(s)
  Kawata M, Saito T, et al.
- Organizer
  Annual meeting of the Orthopaedic Research Society.
- Place of Presentation
  Orlando
- Year and Date
  2016-03-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] 過剰な力学的ストレスによる関節軟骨異化のメカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第10回骨軟骨フロンティア
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] Perspective of disease-modifying osteoarthritis drugs2016
- Author(s)
  Taku Saito
- Organizer
  第3回アジア太平洋骨代謝学会議
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] Regulation of Articular Cartilage Homeostasis and Osteoarthritis Development by the NF-kappaB signaling.2016
- Author(s)
  Taku Saito
- Organizer
  2016 Cold Spring Harbor Asia Conference on Bone & Cartilage
- Place of Presentation
  Suzhou, China
- Year and Date
  2016-10-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 腰椎椎間関節切除によるマウス椎間板変性モデルの樹立2016
- Author(s)
  尾市健、谷口優樹、相馬一仁、矢野文子、田中栄、齋藤琢
- Organizer
  日本整形外科学会基礎学術総会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10811
[Presentation] Notch・Hes1による軟骨細胞の制御機構2016
- Author(s)
  齋藤琢
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 変性性関節症の制御メカニズム2016
- Author(s)
  齋藤琢
- Organizer
  Orthopedic Research Club
- Place of Presentation
  木更津
- Year and Date
  2016-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] 過剰な力学的ストレスによる関節軟骨異化のメカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第10回骨軟骨フロンティア
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] 過剰な力学的ストレス負荷による関節軟骨変性の分子メカニズム2016
- Author(s)
  齋藤琢
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] Perspective of disease-modifying osteoarthritis drugs2016
- Author(s)
  Taku Saito
- Organizer
  第3回アジア太平洋骨代謝学会議
- Place of Presentation
  大阪
- Year and Date
  2016-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] Gait Analyses of Surgically Induced osteoarthritis model mice by motion capture system.2015
- Author(s)
  Makii Y, Saito T, et al.
- Organizer
  Annual meeting of Osteoarthritis Research Society International.
- Place of Presentation
  Washington State Convention Center (Seattle, WA)
- Year and Date
  2015-04-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15535
[Presentation] Notch/Rbpj/Hes1経路による変形性関節症の制御機構2015
- Author(s)
  齋藤琢他
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] Establishment of Surgical Destabilization Model of Mouse Ankle Osteoarthritis.2015
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the Orthopaedic Research Society.
- Place of Presentation
  Las vegas, USA
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] 変形性関節症の分子メカニズム2015
- Author(s)
  齋藤琢他
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] Different regulation of limb development by p63 transcript variants.2015
- Author(s)
  Kawata M, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Seattle
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] Expression and function of CCAAT/enhancer-binding protein family in chondrocytes.2014
- Author(s)
  Okuma T, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston USA
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] 変形性関節症の制御メカニズムの解明2014
- Author(s)
  齋藤琢
- Organizer
  第32回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] HIF-1α REGULATES CONFIGURATION AND MAINTENANCE OF ARTICULAR CARTILAGE THROUGH INDUCTION OF ANABOLIC FACTORS AND SUPPRESSION OF CATABOLIC FACTORS.2014
- Author(s)
  Okada K, Saito T, et al.
- Organizer
  Annual meeting of Osteoarthritis Research Society International.
- Place of Presentation
  Paris
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] IDENTIFICATION OF GREMLIN1 AS A CATABOLIC FACTOR INDUCED BY MECHANICAL STRESS LOADING IN ARTICULAR CHONDROCYTES2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Osteoarthritis Research Society International
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-25670634
[Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston
- Year and Date
  2014-09-15
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] Research on pathophysiology and therapeutic target of osteoarthritis.2014
- Author(s)
  Taku Saito
- Organizer
  16th Asia Pacific League of Associations for Rheumatology Congress (APLAR)
- Place of Presentation
  Cebu City, Philippines
- Year and Date
  2014-04-04
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 軟骨内骨化研究から生まれる実用的研究2014
- Author(s)
  齋藤琢
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] HIF-1α IS ESSENTIAL FOR ARTICULAR CARTILAGE HOMEOSTASIS THROUGH INDUCTION OF ANABOLIC FACTORS AND SUPPRESSION OF CATABOLIC FACTORS.2014
- Author(s)
  Okada K, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston USA
- Year and Date
  2014-09-16
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Cold Spring Harbor Asia conferences.
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-11-05
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston USA
- Year and Date
  2014-09-15
- Data Source
  KAKENHI-PROJECT-26462285
[Presentation] Transcription factor hes1 modulates osteoarthritis development in cooperation with CaMKII.2014
- Author(s)
  Sugita S, Saito T, et al.
- Organizer
  Annual meeting of Osteoarthritis Research Society International.
- Place of Presentation
  Paris
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24592222
[Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston USA
- Year and Date
  2014-09-15
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] Gremlin1は力学的負荷により誘導され、関節軟骨にcatabolicに作用する2014
- Author(s)
  張成虎、齋藤琢ほか
- Organizer
  日本軟骨代謝学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25670634
[Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston
- Year and Date
  2014-09-15
- Data Source
  KAKENHI-PROJECT-25670634
[Presentation] 変形性関節症への応用を目指した軟骨再生研究2014
- Author(s)
  齋藤琢
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] 軟骨におけるNotchシグナルの役割2014
- Author(s)
  齋藤琢
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都
- Year and Date
  2014-02-28
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Identification of Grem1 as a catabolic factor induced by mechanical stress loading in articular chondrocyte.2014
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of Osteoarthritis Research Society International.
- Place of Presentation
  Paris
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-25670634
[Presentation] Expression and function of CCAAT/enhancer-binding protein family in chondrocytes.2014
- Author(s)
  Okuma T, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston USA
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] HIF-1α IS ESSENTIAL FOR ARTICULAR CARTILAGE HOMEOSTASIS THROUGH INDUCTION OF ANABOLIC FACTORS AND SUPPRESSION OF CATABOLIC FACTORS.2014
- Author(s)
  Okada K, Saito T, et al.
- Organizer
  Annual meeting of the American Society for bone and mineral research.
- Place of Presentation
  Houston
- Year and Date
  2014-09-16
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] 変形性関節症への応用を目指した軟骨再生研究2014
- Author(s)
  齋藤琢
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] 変形性関節症の分子メカニズムの解明2013
- Author(s)
  齋藤琢
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23659704
[Presentation] 軟骨分化モニタリングのためのCol2a1-EGFP-iPS細胞の樹立2013
- Author(s)
  齋藤琢
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23659704
[Presentation] HIFによる関節軟骨の変性メカニズム2013
- Author(s)
  齋藤琢
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Year and Date
  2013-10-18
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] 軟骨分化モニタリングのためのCol2a1-EGFP-iPS細胞の樹立2013
- Author(s)
  齋藤琢他
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] 変形性関節症の分子メカニズムの解明2013
- Author(s)
  齋藤琢
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] HIFによる関節軟骨の変性メカニズム2013
- Author(s)
  3) 齋藤琢
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Invited
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] マウスモデルをベースにした変形性関節症の分子メカニズムの解明2012
- Author(s)
  斎藤琢、川口浩
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Notch/Rbpj/Hes1 シグナルによる軟骨内骨化および変形性関節症の制御2012
- Author(s)
  杉田守礼、斎藤琢、保坂陽子、秋山治彦、鄭雄一、川口浩
- Organizer
  第27回日本整形外科学会基礎学術集会(最優秀演題賞受賞)
- Place of Presentation
  名古屋国際会議場、愛知
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Transcriptional induction of ADAMTS5 by NF-κΒ family member RelA in chondrocytes during osteoarthritis development.2012
- Author(s)
  Kobayashi H, Hirata M, Itoh S, Saito T, Nakamura K, Chung UI, and Kawaguchi H
- Organizer
  2012 Cold Spring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases.
- Place of Presentation
  Suzhou, China
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Notch/Rbpj/Hes1 シグナルによる軟骨内骨化および変形性関節症の制御(優秀演題賞受賞).2012
- Author(s)
  杉田守礼、斎藤琢、保坂陽子、深井厚、秋山治彦、中村孝志、鄭雄一、川口浩
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] マウスモデルをベースにした変形性関節症の分子メカニズムの解明2012
- Author(s)
  齋藤琢
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] 軟骨再生医療への新たな取り組み2012
- Author(s)
  齋藤琢
- Organizer
  第30回日本骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] NF-κBファミリーRelAは、ADAMTS5の転写誘導因子として変形性関節症の進行に作用する2012
- Author(s)
  小林寛、齋藤琢, 他
- Organizer
  日本軟骨代謝学会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-09
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Notch/Rbpl/Hes1 signal in chondrocytes modulates osteoarthritis development.2012
- Author(s)
  Sugita S, Hosaka Y, Hikata T, Akiyama H, Long F, Chung UI, Saito T, Kawaguchi H:
- Organizer
  2012 World Congress on Osteoarthritis (OARSI).
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] NF-κBファミリー分子RelA/p65 は軟骨細胞においてADAMTS5を転写誘導して変形性関節症の発症に関与する(シンポジウム:軟骨変性).2012
- Author(s)
  小林寛、平田真、伊藤祥三、斎藤琢、鄭雄一、中村耕三、川口浩
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  ウィル愛知、愛知
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Prevention and repair of cartilage degeneration by a novel thienoindazole-derivative compound.2012
- Author(s)
  Yano F, Hosaka Y, Fukai A, Saito T, Hojo H, Ohba S, Kawaguchi H, Chung UI
- Organizer
  2012 World Congress on Osteoarthritis (OARSI).
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Hes1, a transcriptional target of Notch signaling, modulates endochondral ossification during osteoarthritis development.2012
- Author(s)
  Sugita S, Hosaka Y, Saito T, Nakamura K, Chung UI, and Kawaguchi H
- Organizer
  2012 Cold Spring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases.
- Place of Presentation
  Suzhou, China
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Notch/Rbpjシグナルは骨格形成と変形性関節症の進行において軟骨内骨化の後期分化過程を制御する(シンポジウム:軟骨変性).2012
- Author(s)
  保坂陽子、斎藤琢、杉田守礼、深井厚、日方智宏、秋山治彦、中村孝志、中村耕三、鄭雄一、川口浩
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  ウィル愛知、愛知
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Notch/Rbpj/Hes1 Signal in Chondrocytes Modulates the Terminal Stage of Endochondral Ossification during Skeletal Growth and Osteoarthritis Development2011
- Author(s)
  Hosaka Y, Saito T, et al.
- Organizer
  The American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] 軟骨細胞のNotch/Rbpj/Hes1シグナルは骨格形成および変形性関節症における軟骨内骨化の後期過程を制御する2011
- Author(s)
  保坂陽子、齋藤琢, 他
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] GSK-3αとGSK-3βは協調的にRelA/NF-κB p65のリン酸化を介して軟骨細胞初期分化を制御する2011
- Author(s)
  伊藤祥三、齋藤琢, 他
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Transcriptional induction of ADAMTS5 by NF-κB family member RelA/p65 in chondrocytes during osteoarthritis development2011
- Author(s)
  Kobayashi H, Saito T, et al.
- Organizer
  International Osteoporosis Federation/Australian and New Zealand Bone & Mineral Society (IOF/ANZBMS)
- Place of Presentation
  Gold coast (AUS)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Functional Redundancy of GSK-3α and GSK-3β to Control Chondrocyte Differentiation through Phosphorylation of RelA/NF-κB p652011
- Author(s)
  Itoh S, Saito T, et al.
- Organizer
  The American Society for Bone and Mineral Research(ASBMR)
- Place of Presentation
  San Diego USA
- Data Source
  KAKENHI-PROJECT-23659704
[Presentation] NF-κBファミリーRelAは、ADAMTS5の転写誘導因子として変形性関節症の進行に作用する2011
- Author(s)
  小林寛、齋藤琢, 他
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Transcriptional induction of ADAMTS5 by NF-κΒ family member RelA/p65 in chondrocytes during osteoarthritis development2011
- Author(s)
  Kobayashi H, Saito T, et al.
- Organizer
  International Osteoporosis Federation / Australian and New Zealand Bone & Mineral Society(IOF/ANZBMS)
- Place of Presentation
  Gold Coast Australia
- Data Source
  KAKENHI-PROJECT-23659704
[Presentation] Notch/Rbpj/Hes1 Signal in Chondrocytes Modulates the Terminal Stage of Endochondral Ossification during Skeletal Growth and Osteoarthritis Development2011
- Author(s)
  Hosaka Y, Saito T, et al.
- Organizer
  2011 World Congress on Osteoarthritis
- Place of Presentation
  San Diego USA
- Data Source
  KAKENHI-PROJECT-23659704
[Presentation] C/EBPb and RUNX2 Cooperatively Control Cartilage Degradation with MMP-13 as the Target and HIF-2a as the Inducer in Chondrocytes2011
- Author(s)
  Hirata M, Saito T, et al.
- Organizer
  The American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Functional Redundancy of GSK-3α and GSK-3β to Control Chondrocyte Differentiation through Phosphorylation of RelA/NF-κB p652011
- Author(s)
  Itoh S, Saito T, et al.
- Organizer
  Osteoarthritis Research Society International (OARSI)
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] HIF2A/NF-kBシグナルは変形性関節症を制御する2010
- Author(s)
  齋藤琢, 他
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] A transcription factor p63 controls extensive steps of endochondral ossification through distinct functions of the isoforms.2010
- Author(s)
  Taniguchi Y, Saito T, Nakamura K, et al.
- Organizer
  32th annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto, Canada
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-21659347
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に促進し、骨格成長と関節軟骨変性の両者を制御する2009
- Author(s)
  齋藤琢, 他
- Organizer
  第22回日本軟骨代謝学会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression2009
- Author(s)
  Saito T, et al.
- Organizer
  American Society for Bone and Mineral Research, the 31st annual meeting
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeleta growth and osteoarthritis progression.2009
- Author(s)
  Saito T, Nakamura K, et al.
- Organizer
  31th annual meeting of the American Society for Bone and Mineral Research(ASBMR).
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21659347
[Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification2009
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  2009 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Monteral, Quebec, Canada
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に制御する転写因子である2009
- Author(s)
  齋藤琢, 他
- Organizer
  第3回Bone Research Seminar
- Place of Presentation
  東京
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] NF-kappa B family member RelA/p65, a transcription factor of Sox9, is essential for chondrogenic differentiation and skeletal growth (Young Investigator Award)2009
- Author(s)
  Itoh S, Saito T, Ushita M, Ikeda T, Yano F, Ogata N, Chung UI, Nakamura K, Kawaguchi H
- Organizer
  2009 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Monteral, Quebec, Canada
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression.2009
- Author(s)
  Saito T, et al.
- Organizer
  31th Annual Meeting of the American Society for Bone and Mineral Research.
- Place of Presentation
  Denver, USA.
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Hypoxia-Inducible Factor 2α(HIF-2α) controls sequential steps of endochondral ossification during skeletal growth and. osteoarthritis progression.2009
- Author(s)
  Saito T, et al.
- Organizer
  Second Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society, Sydney
- Place of Presentation
  Australia.
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Akt1 in chondrocytes controls cartilage calcification during osteophyte foration in osteoarthritis2009
- Author(s)
  Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  2009 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Monteral, Quebec, Canada
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-inducible factor 2α(HIF-2a)controls sequential steps of endochondral ossification during skeletal growth and osteoarthritis progression2009
- Author(s)
 齋藤琢, 他
- Organizer
 2^<nd> Joint Meeting of the International Bone & Mineral Society and the Australian & New Zealand Bone & Mineral Society
- Place of Presentation
 Sydney, Australia
- Year and Date
 2009-03-24
- Data Source
 KAKENHI-PROJECT-20689028
[Presentation] Notch/RBPJk/Hes1 signaling controls terminal differentiation of chondrocytes during endochondral ossification2009
- Author(s)
  Hikata T, Saito T, Takaishi H, Akiyama H, Nakamura T, Yamaguchi A, Matsumoto M, Chiba K, Toyama Y, Kawaguchi H
- Organizer
  31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Denver, Colorado, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] A novel thienoindazole-derivative small compound induces chondrogenic differentiation without promoting hypertrophy through Runx1 (Young Investigator Award)2009
- Author(s)
  Yano F, Ikeda T, Saito T, Ogata N, Hojo H, Kimura A, Takeda S, Takato T, Nakamura K, Kawaguchi H, Chung UI
- Organizer
  31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Denver, Colorado, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Notch/RBPJk/Hes1 Signaling Controls Terminal Differentiation of Chondrocytes during Endochondral Ossification.2009
- Author(s)
  Saito T, Hikata T, et al.
- Organizer
  31th Annual Meeting of the American Society for Bone and Mineral Research.
- Place of Presentation
  Denver, USA.
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に促進し、骨格成長と関節軟骨変性の両者を制御する2009
- Author(s)
  齋藤琢, 他
- Organizer
  第22回日本軟骨代謝学会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression2009
- Author(s)
  Saito T, Fukai A, Ikeda T, Yano F, Hirata M, Kan A, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Denver, Colorado, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-inducible factor 2A (HIF2A) controls sequential steps in the late stage of endochondral ossification (Young Investigator Award)2008
- Author(s)
  Saito T, Ikeda T, Kan A, Hirata M, Fukai A, Yano F, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  2008 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] HIF2Aは軟骨内骨化における軟骨細胞の後期分化を広く制御する転写因子である2008
- Author(s)
  齋藤琢, 他
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に制御する転写因子である2008
- Author(s)
  斎藤琢
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-Inducible Factor 2A (HIF2A)Controls Sequential Steps in the Late Stage of Endochondral Ossification2008
- Author(s)
  齋藤琢, 他
- Organizer
  Osteoarthritis Research Society International, World Congress 2008
- Place of Presentation
  Rome, Italy
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Hypoxia-inducible factor 2A (HIF2A) controls sequential steps in the late stage of endochondarl ossification (Young Investigator Award)2008
- Author(s)
 Saito T
- Organizer
 30^<th>ASBMR Annual Meeting
- Place of Presentation
 Montrial. Quebec. Canada
- Year and Date
 2008-09-12
- Data Source
 KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に制御する転写因子である2008
- Author(s)
  齋藤琢, 他
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪、大阪国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に制御する転写因子である2008
- Author(s)
  齋藤琢, 他
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] HIF2Aは軟骨内骨化における軟骨細胞の後期分化を広く制御する転写因子である2008
- Author(s)
  齋藤琢, 他
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Identification of a transcription factor p63 for transactivation of Wnt9a and Gdf5 causing joint cartilage formation2008
- Author(s)
  Kan A, Ikeda T, Saito T, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Montreal, Quebec, Canada
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-inducible factor 2α(HIF-2α)は軟骨内骨化を統合的に制御する転写因子である2008
- Author(s)
  齋藤琢, 他
- Organizer
  第11回骨発生・再生研究会
- Place of Presentation
  東京
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] A Novel small thienoindazole-derivative compound promotes chondrogenic differentiation without inducing hypertrophy through production of Runx1 (Young Investigator Award)2008
- Author(s)
  Yano F, Ikeda T, Saito T, Ogata N, Nakamura K, Takato T, Kawaguchi H, Chung UI
- Organizer
  2008 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] HIF-2Aは軟骨内骨化における軟骨細胞の後期分化を広く制御する転写因子である2008
- Author(s)
  斎藤琢
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-Inducible Factor 2A (HIF2A) Controls Sequential Steps in Endochondral Ossification.2008
- Author(s)
  Saito T et, al.
- Organizer
  5th Meeting of the Bone Biology Forum, Susono
- Place of Presentation
  Japan.
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] Hypoxia-Inducible Factor 2A (HIF2A) Controls Sequential Steps in the Late Stage of Endochondral Ossification.2008
- Author(s)
  Saito T, et al.
- Organizer
  2008 World Congress on Osteoarthritis, Rome
- Place of Presentation
  Italy.
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-20689028
[Presentation] p63 plays a central role in cartilage development by directly regulating key genes for chondrogenesis2007
- Author(s)
  Ikeda T, Kawaguchi H, Saito T, Kan A, Yano F, Ushita M, Kawasaki Y, Nakamura K, Chung UI
- Organizer
  29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Transcriptional induction of type X collagen expression and hypertrophic differentiation of chondrocytes by Runx2 during osteoarthritis progression (Young Investigator Award)2007
- Author(s)
  Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  2007 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Ft. Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Identification of sorting nexin 19 as a novel chondrogenic factor by a real-time fluorescence monitoring cell line ATDC5-S2RD5 (Young Investigator Award)2007
- Author(s)
  Kan A, Ikeda T, Saito T, Ushita M, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  2007 World Congress on Osteoarthritis (OARSI)
- Place of Presentation
  Ft. Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Transcriptional regulation of type X collagen by Runx2 : Molecular network underlying chondrocyte hypertrophy causing osteoarthritis2007
- Author(s)
  Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Runx1, co-activator of Sox5, Sox6 and Sox9 (the Sox trio) regulates chondrogenic differentiation2007
- Author(s)
  Yano F, Ikeda T, Saito T, Ogata N, Takeda S, Kimura A, Ohba S, Kugimiya F, Nakamura K, Takato T, Kawaguchi H, Chung UI
- Organizer
  29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Transcriptional induction of SOX9 by NF-κB subunit p65 during chondrogenesis2007
- Author(s)
  Ushita M, Ikeda T, Saito T, Kan A, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Hypoxia-inducible factor 2α induces type X collagen and promotes hypertrophic differentiation of chondrocytes2007
- Author(s)
  Saito T, Ikeda T, Higashikawa A, Kawasaki Y, Kan A, Ushita M, Ohba S, Yano F, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Identification of a novel chondrogenic factor Sorting Nexin 19 using a real-time fluorescence monitoring cell line ATDC5-S2RD52007
- Author(s)
  Kan A, Ikeda T, Saito T, Chung UI, Kawaguchi H
- Organizer
  29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19109007
[Presentation] Osteo-chondrogenic function of BMP isdirected toward osteogenesis by Hh-Gli1 in the perichondrium.
- Author(s)
  Hojo H, Ohba S, Taniguchi K, Shirai M,Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, Kawaguchi H, Kambara H, Chung UI
- Organizer
  2012 American Society for Bone and Mineral Research (ASBMR).2012. 10.12-15 (Minneaplis, Minnesota, USA).
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Gli1 participates in the Indian Hedgehog-mediated osteogenesis during endochondral ossification. 2012 American Society for Bone and Mineral Research (ASBMR).
- Author(s)
  Hojo H, Ohba S, Yano F, Saito T, Ikeda T,Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI
- Organizer
  2012. 10.12-15 (Minneaplis, Minnesota, USA).
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] HIFによる関節軟骨の変性メカニズム
- Author(s)
  齋藤　琢
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉（幕張メッセ）
- Invited
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] 軟骨におけるNotchシグナルの役割
- Author(s)
  齋藤　琢
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都（京都府医師会館）
- Invited
- Data Source
  KAKENHI-PROJECT-23689065
[Presentation] Rbpj-dependent Notch signaling in chondrocytes modulates endochondral ossification during osteoarthritis development through transcriptional induction by Hes1 (Young Investigator Award).
- Author(s)
  Sugita S, Hosaka Y, Saito T, Akiyama H, Chung UI, Kawaguchi H
- Organizer
  2012 American Society for Bone and Mineral Research (ASBMR).2012. 10.12-15 (Minneaplis, Minnesota, USA).
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Establishment of Surgical Destabilization Model of Mouse Ankle Osteoarthritis.
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the Orthopaedic Research Society.
- Place of Presentation
  Las vegas, USA
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-25293316
[Presentation] RBPjκ-dependent Notch signaling in chondrocytes modulates skeletal growth and osteoarthritis development.
- Author(s)
  Hosaka Y, Saito T, Sugita S, Fukai A, Hikata T, Akiyama H, Nakamura T, Nakamura K, Chung UI, Kawaguchi H
- Organizer
  2012 Cold Spring Harbor Asia Conference: Bone & Cartilage: From Development to Human Diseases. 2012. 6. 11-15 (Suzhou, China).
- Data Source
  KAKENHI-PROJECT-22249056
[Presentation] Establishment of Surgical Destabilization Model of Mouse Ankle Osteoarthritis
- Author(s)
  Chang SH, Saito T, et al.
- Organizer
  Annual meeting of the Orthopaedic Research Society.
- Place of Presentation
  Las vegas, USA
- Year and Date
  2015-03-28 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-26293330
[Presentation] Research on pathophysiology and therapeutic target of osteoarthritis
- Author(s)
  Saito T
- Organizer
  16th Asia Pacific League of Associations for Rheumatology Congress (APLAR)
- Place of Presentation
  Cebu City, Philippines
- Invited
- Data Source
  KAKENHI-PROJECT-23689065
[]
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[]

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# of Collaborated Projects: 8 results

# of Collaborated Products: 1 results
2. TANAKA Sakae (50282661)

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# of Collaborated Products: 29 results
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# of Collaborated Projects: 5 results

# of Collaborated Products: 53 results
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Saito Taku 齋藤 琢

SAITO Taku 齋藤 琢

斉藤 琢 サイトウ タク

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関節運動に呼応した滑膜-軟骨連関から紐解く関節の恒常性維持機構Principal Investigator

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Development of tendon/ligament repair modulater using a chemically modified Tetra-PEG gel with signal transduction capabilityPrincipal Investigator

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Identification of anti-inflammatory subsets of MSCs and their clinical applicationPrincipal Investigator

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Molecular mechanisms underlying homeostasis of artiuclar jointPrincipal Investigator

Saito Taku 齋藤琢

SAITO Taku 齋藤琢

斉藤琢サイトウタク