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Taniguchi Yuki  谷口 優樹

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TANIGUCHI Yuki  谷口 優樹

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Researcher Number 80722165
Affiliation (Current) 2022: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help 2019 – 2020: 東京大学, 医学部附属病院, 特任准教授
2014 – 2020: 東京大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords
Principal Investigator
椎間板 / 椎間板変性 / 椎間板変性モデル / FBN1 / マルファン症候群 / Fbn1 / 側弯症 / ADAMTS10 / ADAMTS17 / 成長障害 … More / フィブリリン / ADAMTSファミリー / Runx2 / Runx3 / 変形性関節症 / RNAシークエンス / ChIPシークエンス / 関節軟骨 / 転写制御機構 … More
Except Principal Investigator
後縦靭帯骨化症 / 整形外科学 / 軟骨代謝学 / 頚椎後縦靭帯骨化症 / RSPO2 / Wnt経路 / OPLL / GWAS / Rspo2 / 靱帯 / 後縦靭帯 / 骨化 / メカニカルストレス / Wntシグナル / 医療・福祉 / 運動器 / 脊椎 / 変形性膝関節症 / ルブリシン / Prg4 / シングルセル解析 / 軟部肉腫 / 深層学習 / 肉腫 / RNA-seq解析 Less
  • Research Projects

    (10 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (34 People)
  •  シングルセル解析技術に立脚した傍脊柱靱帯の構成細胞解析と後縦靭帯骨化症の病態解明

    • Principal Investigator
      大島 寧
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokyo
  •  Runx2,3による関節軟骨の統合的制御機構の解明Principal Investigator

    • Principal Investigator
      谷口 優樹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokyo
  •  RNA-seq解析における深層学習方法論の開発と肉腫診療への応用

    • Principal Investigator
      小林 寛
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokyo
  •  Runx2,3による関節軟骨の統合的制御機構の解明

    • Principal Investigator
      相馬 一仁
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokyo
  •  Prg4 を標的とした変形性関節症治療薬開発のための基盤研究

    • Principal Investigator
      矢野 文子
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokyo
  •  Possible novel therapy of degenerated intervertebral disc by ADAMTS10Principal Investigator

    • Principal Investigator
      Taniguchi Yuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Function of RSPO2 in progerssion of OPLL

    • Principal Investigator
      Matsubayashi Yoshitaka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Basic research for a long-life spinal implant providing dynamic stability and anti-infective property

    • Principal Investigator
      Oshima Yasushi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  What causes overgrowth and scoliosis in Marfan syndrome?Principal Investigator

    • Principal Investigator
      Taniguchi Yuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Roles of DIO family members and thyroid hormone in articular cartilage

    • Principal Investigator
      YAMAGAMI Ryota
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2015 2014

All Journal Article

  • [Journal Article] Tracheal stenosis due to cervicothoracic hyperlordosis in patients with cerebral palsy treated with posterior spinal fusion: a report of the first two cases2021

    • Author(s)
      Taniguchi Yuki、Matsubayashi Yoshitaka、Kato So、Oguchi Fumihiko、Nohara Ayato、Doi Toru、Oshima Yasushi、Tanaka Sakae
    • Journal Title

      BMC Musculoskeletal Disorders

      Volume: 22

    • DOI

      10.1186/s12891-021-04094-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021
  • [Journal Article] Association Between Deep Posterior Cervical Paraspinal Muscle Morphology and Clinical Features in Patients With Cervical Ossification of the Posterior Longitudinal Ligament2021

    • Author(s)
      Doi Toru、Ohtomo Nozomu、Oguchi Fumihiko、Tozawa Keiichiro、Nakarai Hiroyuki、Nakajima Koji、Sakamoto Ryuji、Okamoto Naoki、Nakamoto Hideki、Kato So、Taniguchi Yuki、Matsubayashi Yoshitaka、Oka Hiroyuki、Matsudaira Ko、Tanaka Sakae、Oshima Yasushi
    • Journal Title

      Global Spine Journal

      Volume: -

    • DOI

      10.1177/2192568221989655

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021, KAKENHI-PROJECT-19K24022
  • [Journal Article] TRPV2 is involved in induction of lubricin and suppression of ectopic endochondral ossification in articular joints2021

    • Author(s)
      Nakamoto Hideki、Katanosaka Yuki、Chijimatsu Ryota、Mori Daisuke、Xuan Fengjun、Yano Fumiko、Omata Yasunori、Maenohara Yuji、Murahashi Yasutaka、Kawaguchi Kohei、Yamagami Ryota、Inui Hiroshi、Taketomi Shuji、Taniguchi Yuki、Kanagawa Motoi、Naruse Keiji、Tanaka Sakae、Saito Taku
    • Journal Title

      Arthritis & Rheumatology

      Volume: -

    • DOI

      10.1002/art.41684

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-20K09428, KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K22677
  • [Journal Article] Diabetes is associated with greater leg pain and worse patient-reported outcomes at 1 year after lumbar spine surgery2021

    • Author(s)
      Nagata Kosei、Nakamoto Hideki、Kato So、Kawamura Naohiro、Nakarai Hiroyuki、Higashikawa Akiro、Iizuka Masaaki、Ono Takashi、Fukushima Masayoshi、Sasaki Katsuyuki、Okazaki Rentaro、Ito Yusuke、Hara Nobuhiro、Doi Toru、Taniguchi Yuki、Oshima Yasushi et al.
    • Journal Title

      Scientific Reports

      Volume: 11

    • DOI

      10.1038/s41598-021-87615-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451
  • [Journal Article] Associations between curve severity and revised Scoliosis Research Society-22 and scoliosis Japanese Questionnaire-27 scores in female patients with adolescent idiopathic scoliosis: a multicenter, cross-sectional study2021

    • Author(s)
      Doi Toru、Watanabe Kei、Doi Tokuhide、Inoue Hirokazu、Sugawara Ryo、Arai Yasuhisa、Shirado Osamu、Yamazaki Ken、Uno Koki、Yanagida Haruhisa、Kato So、Taniguchi Yuki、Matsubayashi Yoshitaka、Oshima Yasushi、Tanaka Sakae、Takeshita Katsushi
    • Journal Title

      BMC Musculoskeletal Disorders

      Volume: 22

    • DOI

      10.1186/s12891-021-04189-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021
  • [Journal Article] Influence of unintended dural tears on postoperative outcomes in lumbar surgery patients: a multicenter observational study with propensity scoring2020

    • Author(s)
      Nakajima Koji、Nakamoto Hideki、Kato So、Doi Toru、Matsubayashi Yoshitaka、Taniguchi Yuki、Kawamura Naohiro、Higashikawa Akiro、Takeshita Yujiro、Fukushima Masayoshi、Ono Takashi、Hara Nobuhiro、Azuma Seiichi、Tanaka Sakae、Oshima Yasushi
    • Journal Title

      The Spine Journal

      Volume: 20 Pages: 1968-1975

    • DOI

      10.1016/j.spinee.2020.06.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021
  • [Journal Article] Pathomechanism of intervertebral disc degeneration2020

    • Author(s)
      Oichi Takeshi、Taniguchi Yuki、Oshima Yasushi、Tanaka Sakae、Saito Taku
    • Journal Title

      JOR SPINE

      Volume: 3

    • DOI

      10.1002/jsp2.1076

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451
  • [Journal Article] Comparison Between the Japanese Orthopaedic Association (JOA) Score and Patient-Reported JOA (PRO-JOA) Score to Evaluate Surgical Outcomes of Degenerative Cervical Myelopathy2020

    • Author(s)
      Oshima Yasushi、Takeshita Katsushi、Kato So、Doi Toru、Matsubayashi Yoshitaka、Taniguchi Yuki、Nakajima Koji、Oguchi Fumihiko、Okamoto Naoki、Sakamoto Ryuji、Tanaka Sakae
    • Journal Title

      Global Spine Journal

      Volume: -

    • DOI

      10.1177/2192568220964167

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021, KAKENHI-PROJECT-19K24022
  • [Journal Article] Risk factors for progression of ossification of the posterior longitudinal ligament in asymptomatic subjects2020

    • Author(s)
      Doi Toru、Sakamoto Ryuji、Horii Chiaki、Okamoto Naoki、Nakajima Koji、Hirai Shima、Oguchi Fumihiko、Kato So、Taniguchi Yuki、Matsubayashi Yoshitaka、Hayashi Naoto、Tanaka Sakae、Oshima Yasushi
    • Journal Title

      Journal of Neurosurgery: Spine

      Volume: 33 Pages: 316-322

    • DOI

      10.3171/2020.3.spine2082

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021
  • [Journal Article] A Multicenter Observational Study on the Postoperative Outcomes of C3 Laminectomy in Cervical Double-door Laminoplasty2020

    • Author(s)
      Nakajima Koji、Nakamoto Hideki、Kato So、Doi Toru、Matsubayashi Yoshitaka、Taniguchi Yuki、Yoshida Yuichi、Kawamura Naohiro、Nakarai Hiroyuki、Higashikawa Akiro、Tozawa Keiichiro、Takeshita Yujiro、Fukushima Masayoshi、Iizuka Masaaki、Ono Takashi、Shirokoshi Tomohiko、Azuma Seiichi、Tanaka Sakae、Oshima Yasushi
    • Journal Title

      Clinical Spine Surgery: A Spine Publication

      Volume: Publish Ahead of Print

    • DOI

      10.1097/bsd.0000000000001100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09451, KAKENHI-PROJECT-20K18021
  • [Journal Article] Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.2019

    • Author(s)
      Oichi Takeshi、Taniguchi Yuki、Soma Kazuhito、Oshima Yasushi、Yano Fumiko、Mori Yoshifumi、Chijimatsu Ryota、Kim-Kaneyama Joo-ri、Tanaka Sakae、Saito Taku
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 76 Pages: 4795-4809

    • DOI

      10.1007/s00018-019-03188-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10924
  • [Journal Article] Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 22015

    • Author(s)
      Sugita S, Taketomi S, Saito T, et al.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 112 Pages: 3080-3085

    • DOI

      10.1073/pnas.1419699112

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-25713052, KAKENHI-PROJECT-26713054
  • [Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine2014

    • Author(s)
      Nakajima M, Takahashi A, Tsuji T, Furukawa K-I et al.
    • Journal Title

      Nat Genet

      Volume: 46 Pages: 1012-1016

    • DOI

      10.1038/ng.3045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590310, KAKENHI-PROJECT-24592194, KAKENHI-PROJECT-26293332, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-221S0001
  • 1.  齋藤 琢 (30456107)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 2.  Oshima Yasushi (50570016)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 9 results
  • 3.  Matsubayashi Yoshitaka (50747962)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  筑田 博隆 (30345219)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YAMAGAMI Ryota (00722191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MORIZAKI Yutaka (30508099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  竹下 克志 (30262009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  池田 敏之 (80322759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  石原 一彦 (90193341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  高取 吉雄 (40179461)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  茂呂 徹 (20302698)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  大嶋 浩文 (00622359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  相馬 一仁 (80724989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  矢野 文子 (80529040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  前田 真吾 (60353463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  小林 寛 (20407951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  篠田 裕介 (80456110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKETOMI Shuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 19.  OHBA Shinsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  TANAKA Hideo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  KUBO Michiaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  金山 朱里
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  加藤 壯
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 24.  坂本 龍司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  乾 洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  川口 浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  古川 賢一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  森 幹士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  大川 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  高橋 悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  高橋 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  田中 恵太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  田中 祐吉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  田中 勇悦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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