Taniguchi Yuki 谷口優樹

… Alternative Names

Researcher Number	80722165
Affiliation (Current)	2021: 東京大学, 医学部附属病院, 特任准教授
Affiliation (based on the past Project Information) *help	2019 – 2020: 東京大学, 医学部附属病院, 特任准教授 2014 – 2020: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords	Principal Investigator 椎間板 / 椎間板変性 / 椎間板変性モデル / FBN1 / マルファン症候群 / Fbn1 / 側弯症 / ADAMTS10 / ADAMTS17 / 成長障害 … More Except Principal Investigator 後縦靭帯骨化症 / 整形外科学 / 軟骨代謝学 / 頚椎後縦靭帯骨化症 / RSPO2 / Wnt経路 / OPLL / GWAS / Rspo2 / 靱帯 / 後縦靭帯 / 骨化 / メカニカルストレス / Wntシグナル / 医療・福祉 / 運動器 / 脊椎 / 変形性膝関節症 / ルブリシン / Prg4 / 肉腫 / 深層学習 / RNA-seq解析 / シングルセル解析 Less

Runx2,3による関節軟骨の統合的制御機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  谷口優樹
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
RNA-seq解析における深層学習方法論の開発と肉腫診療への応用Ongoing
- Principal Investigator
  
  小林寛
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
シングルセル解析技術に立脚した傍脊柱靱帯の構成細胞解析と後縦靭帯骨化症の病態解明Ongoing
- Principal Investigator
  
  大島寧
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Runx2,3による関節軟骨の統合的制御機構の解明
- Principal Investigator
  
  相馬一仁
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Prg4 を標的とした変形性関節症治療薬開発のための基盤研究Ongoing
- Principal Investigator
  
  矢野文子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
Possible novel therapy of degenerated intervertebral disc by ADAMTS10Principal Investigator
- Principal Investigator
  
  Taniguchi Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Function of RSPO2 in progerssion of OPLL
- Principal Investigator
  
  Matsubayashi Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Basic research for a long-life spinal implant providing dynamic stability and anti-infective property
- Principal Investigator
  
  Oshima Yasushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
What causes overgrowth and scoliosis in Marfan syndrome?Principal Investigator
- Principal Investigator
  
  Taniguchi Yuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Roles of DIO family members and thyroid hormone in articular cartilage
- Principal Investigator
  
  YAMAGAMI Ryota
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo

All 2019 2015 2014

All Journal Article

[Journal Article] Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.2019
- Author(s)
  Oichi Takeshi、Taniguchi Yuki、Soma Kazuhito、Oshima Yasushi、Yano Fumiko、Mori Yoshifumi、Chijimatsu Ryota、Kim-Kaneyama Joo-ri、Tanaka Sakae、Saito Taku
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 76 Pages: 4795-4809
- DOI
  10.1007/s00018-019-03188-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08404, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-17K10924
[Journal Article] Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 22015
- Author(s)
  Sugita S, Taketomi S, Saito T, et al.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 Pages: 3080-3085
- DOI
  10.1073/pnas.1419699112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-25713052, KAKENHI-PROJECT-26713054
[Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine2014
- Author(s)
  Nakajima M, Takahashi A, Tsuji T, Furukawa K-I et al.
- Journal Title
  
  Nat Genet
  
  Volume: 46 Pages: 1012-1016
- DOI
  10.1038/ng.3045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590310, KAKENHI-PROJECT-24592194, KAKENHI-PROJECT-26293332, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-221S0001

1. 齋藤琢 (30456107)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. Oshima Yasushi (50570016)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Matsubayashi Yoshitaka (50747962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 筑田博隆 (30345219)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAMAGAMI Ryota (00722191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIZAKI Yutaka (30508099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 竹下克志 (30262009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 池田敏之 (80322759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石原一彦 (90193341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高取吉雄 (40179461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 茂呂徹 (20302698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大嶋浩文 (00622359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 相馬一仁 (80724989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 矢野文子 (80529040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 小林寛 (20407951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 篠田裕介 (80456110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 前田真吾 (60353463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKETOMI Shuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. OHBA Shinsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. TANAKA Hideo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. KUBO Michiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 川口浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 古川賢一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 森幹士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 大川淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 高橋悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 高橋隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 田中恵太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 田中祐吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 田中勇悦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 金山朱里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taniguchi Yuki 谷口 優樹

TANIGUCHI Yuki 谷口 優樹

Research Projects

Research Products

Co-Researchers

Runx2,3による関節軟骨の統合的制御機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA-seq解析における深層学習方法論の開発と肉腫診療への応用Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シングルセル解析技術に立脚した傍脊柱靱帯の構成細胞解析と後縦靭帯骨化症の病態解明Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Runx2,3による関節軟骨の統合的制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prg4 を標的とした変形性関節症治療薬開発のための基盤研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Possible novel therapy of degenerated intervertebral disc by ADAMTS10Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of RSPO2 in progerssion of OPLL

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research for a long-life spinal implant providing dynamic stability and anti-infective property

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

What causes overgrowth and scoliosis in Marfan syndrome?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of DIO family members and thyroid hormone in articular cartilage

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 22015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine2014

Author(s)

Journal Title

DOI

Data Source

Taniguchi Yuki 谷口優樹

TANIGUCHI Yuki 谷口優樹