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Ikeda Toshiyuki  池田 敏之

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… Alternative Names

IKEDA Toshiyuki  池田 敏之

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Researcher Number 80322759
Other IDs
External Links
Affiliation (Current) 2020: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help 2018 – 2019: 東京大学, 医学部附属病院, 助教
2017: 東京大学, 医学部附属病院, その他
2013 – 2016: 東京大学, 医学部附属病院, 助教
2011: 東京大学, 医学部・附属病院, 助教
2011: 東京大学, 医学部附属病院, 特任助教 … More
2009: 東京大学, 医学部附属病院, 助教
2009: 東京大学, 医学部附属病院, 医員
2008 – 2009: 東京大学, 医学部附属病院, 特任助教
2008: The University of Tokyo, 医学部・附属病院, 特任助教
2007: The University of Tokyo, Faculty of Medicine, Visiting Assistant Professor
2006 – 2007: Tokyo Univ, Faculty of Medicine, Visiting Research Associate, 医学部附属病院, 客員教員
2006: The university of Tokyo, Faculty of Medicine, Visiting Research Associate, 医学部附属病院, 客員教授
2005: 東京大学, 医学部附属病院, 助手
2005: The University of Tokyo, Hospital, Visiting Assistant Professor, 医学部附属病院, 客員助手
2004 – 2005: 東京大学, 医学部附属病院, 寄附講座教員
2003: 東京大学, 医学部附属病院, 助手
2000: Univ.of Tokyo, Assistant, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Orthopaedic surgery / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Orthopaedic surgery / Kidney internal medicine / Laboratory medicine
Keywords
Principal Investigator
軟骨分化 / 転写因子 / SOX6 / p63 / 選択的スプライシング / SOX9 / S100A1 / S100B / SNX19 / CILP … More / SOX5 / 軟骨代謝 / 多血小板血漿 / クリオプレシピテート / PDGFβ / EMX / SOX / 輸血療法 / SOXトリオ / 血小板由来増殖因子 / ヒアルロン酸 / ヒアルロン酸合成酵素タイプ2 / 変形性関節症 / 関節軟骨 / アデノウィルスベクター / 遺伝子治療 / ヒアルロン酸合成酵素タイプン / アデノウィルス / 変形性膝関節症 / hyaluronic acid / hyaluronic acid synthetase type 2 / Osleoarthritis / Articular cartilage / adeno virus vector / gene therapy / ノッチシグナル / II型コラーゲン / レトロウィルスcDNAライブラリー / SOXトリオ / マイクロアレイ / S100 / ATDC5 / Chondrogenic differentiation / 血球分化 / アポトーシス / 血液型D抗原 / SRSF / スプライシング / 軟骨再生 / がん抑制 … More
Except Principal Investigator
骨 / 軟骨代謝 / 軟骨分化 / 軟骨代謝学 / 転写因子 / 軟骨 / 変形性関節症 / cGKII / 成長板 / Sox9 / p63 / 軟骨細胞 / 軟骨内骨化 / 遺伝子 / 画像解析 / 疫学 / ゲノム / バーター症候群 / カルシウム代謝 / 腎機能低下 / 副甲状腺機能低下症 / Ca感知受容体 / 腎電解質異常 / 低Ca血症 / 慢性腎不全 / 骨異栄養症 / 遺伝子治療 / 遺伝子治療3 / カルシウム感知受容体 / 腎電解質代謝 / 低カルシウム血症 / 高カリウム血症 / 高リン血症 / 関節病学 / 永久関節軟骨再生 / 整形外科学 / 関節軟骨細胞 / メカニカルストレス / 椎間板変性 / 椎間板変性モデル / FBN1 / マルファン症候群 / Fbn1 / 側弯症 / 椎間板 / 胚性幹(ES)細胞 / 骨分化 / 分化十分条件 / 培養方法 / 再生医学 / 再生 / 胚性幹細胞 / 分化誘導 / 幹細胞 / 胚性幹細胞(ES) / embryonic stem (ES) cells / osteoblast differentiation / chondrocyte differentiation / optimal differentiation condition / culture methods / regenerative medicine / 骨軟骨代謝学 / 関節再生 / 転写制御 / WNT9A / GDF5 / HMG / ATX / Cartilage Metabolism / Joint Development / Transcription Factor / アディポネクチン / 脂肪 / 骨粗鬆症 / 骨形成 / ノックアウトマウス / トランスジェニックマウス / Adiponectin / bone / lipid / osteoporosis / HPA抗原 / 抗HPA抗体 / 遺伝子導入細胞 / HPA / 遺伝子導入 / xMAPテクノロジー / 免疫血清学 Less
  • Research Projects

    (18 results)
  • Research Products

    (122 results)
  • Co-Researchers

    (45 People)
  •  新規軟骨分化誘導転写因子EMX2を制御する分子間ネットワークの解明Principal InvestigatorOngoing

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      The University of Tokyo
  •  Development of a new method for platelet antibody testing using transfected cell line

    • Principal Investigator
      Matsuhashi Mika
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      The University of Tokyo
      Saitama Prefectural University
  •  Investigation of the regulatory mechanisms of alternative splicing that regulate cartilage development, hematopoietic differentiation and tumor suppressionPrincipal Investigator

    • Principal Investigator
      IKEDA Toshiyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  What causes overgrowth and scoliosis in Marfan syndrome?

    • Principal Investigator
      Taniguchi Yuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Investigation of molecular mechanisms of chondrogenesis by platelet rich plasmaPrincipal Investigator

    • Principal Investigator
      Ikeda Toshiyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Analyses of mechano-sensing pathways in chondrocytes using cyclic hydroctatic pressure model

    • Principal Investigator
      SAITO Taku
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Molecular mechanisms of joint formation by transcription factor SOX11

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  The integrated study for molecular backgrounds and therapeutic targets of osteoarthritis : The ROAD project.

    • Principal Investigator
      NAKAMURA Kozo
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      国立障害者リハビリテーションセンター(研究所)
      The University of Tokyo
  •  Where is the cause of Bartter's syndrome in the kidney?

    • Principal Investigator
      WATANABE Sumiyo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  新規軟骨分化誘導因子ZSCANCの機能解析Principal Investigator

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Research of the Molecular Network Regulating Endochondral Ossification

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Expression Cloning of Joint Regenerative Genes

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
      The University of Tokyo
  •  Regulation of Bone Formation by Adiponectin

    • Principal Investigator
      MATSUDAIRA Ko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  変形性関節症で誘導される軟骨特異的遺伝子CILPのプロモーター解析Principal Investigator

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic Research for Upstream Molecules, Target molecules and Co-factors of the SOX trio, the Essential Transcription Factors for ChondrogenesisPrincipal Investigator

    • Principal Investigator
      IKEDA Toshiyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  新規軟骨分化制御因子cGK2シグナルの骨再正における機能解析とその標的分子の同定

    • Principal Investigator
      筑田 博隆
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic study on osteoblast and chondrocyte differentiation from embryonic stem (ES) cells

    • Principal Investigator
      CHUNG Ung-il
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  The Studies towards Prevention of Osteoarthritis of the knee joint Using Adenovirus Vector Encording Hyaluronic Acid Synthe tase Type-2 GenePrincipal Investigator

    • Principal Investigator
      IKEDA Toshiyuki, 坪井 寿和
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The Univ. of Tokyo

All 2019 2018 2017 2016 2015 2014 2013 2012 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] 技術講座 輸血 -step up編-クリニカルパスと自己血輸血2018

    • Author(s)
      池田 敏之
    • Journal Title

      検査と技術

      Volume: 46 Pages: 110-120

    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Journal Article] Development of RBC transfusion indications and the collection of patient-specific pre-transfusion information.2017

    • Author(s)
      Yazer MH, van de Watering L, Okazaki H, Ikeda T, Nagura Y et al
    • Journal Title

      Vox Sang.

      Volume: 112

    • DOI

      10.1111/vox.12509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Journal Article] Pilot study on novel blood containers with alternative plasticizers for red cell concentrate storage.2017

    • Author(s)
      Morishita Y, Nomura Y, Fukui C, Kawakami T, Ikeda T, Mukai T, Yuba T, Inamura KI, Yamaoka H, Miyazaki KI, Okazaki H, Haishima Y
    • Journal Title

      PLoS One

      Volume: 12

    • DOI

      10.1371/journal.pone.0185737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Journal Article] Targeting gene expression to specific cells of kidney tubules in vivo, using adenoviral promoter fragments2017

    • Author(s)
      Sumiyo Watanabe , Toru Ogasawara, Yoshifuru Tamura, Taku Saito, Toshiyuki Ikeda, Nobuchika Suzuki, Tatsuo Shimosawa, Shigeru Shibata, Ung-il Chung, Masaomi Nangaku, Shunya Uchida
    • Journal Title

      PLOS One

      Volume: 12 Pages: 1-14

    • DOI

      10.1371/journal.pone.0168638

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09683, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-26293330
  • [Journal Article] Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p632017

    • Author(s)
      Taniguchi Y, Kawata M, Chang SH, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills AA, Chung UI, Tanaka S, Kawaguchi H, and Saito T*
    • Journal Title

      Arthritis & Rheumatology

      Volume: 69 Pages: 598-609

    • DOI

      10.1002/art.39976

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-26293330
  • [Journal Article] Identification of SCAN Domain Zinc-Finger Gene ZNF449 as a Novel Factor of Chondrogenesis2014

    • Author(s)
      Okada K, Saito T, et al.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0115169

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-25713052
  • [Journal Article] Anovel disease-modifying osteoarthritis drug candidate targeting Runxl.2013

    • Author(s)
      Yano, F. et al.
    • Journal Title

      Arthritis Rheum

      Volume: 72 Pages: 429-435

    • DOI

      10.1136/annrheumdis-2012-201745

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390416, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23659710, KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25462358, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25713052
  • [Journal Article] Gli1 participates in the hedgehog-mediated specification of the osteoblast lineage during endochondral ossification.2013

    • Author(s)
      Hojo H, et al.
    • Journal Title

      J Biol Chem.

      Volume: 288 Pages: 17860-17869

    • DOI

      10.1074/jbc.m112.409342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04835, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390460, KAKENHI-PROJECT-24240069, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25462358, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
  • [Journal Article] C/EBP-βand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2αas the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume: 21 Pages: 1111-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum-US

      Volume: 64 Pages: 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 62 Pages: 826-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 62

      Pages: 826-836

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, et.al.
    • Journal Title

      Arthritis Rheum. 62(3)

      Pages: 826-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Aktl in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa A, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 62(3)

      Pages: 826-36

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2αduring skeletal growth and osteoarthritis development2010

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, and Kawaguchi H
    • Journal Title

      Nat Med

      Volume: 16 Pages: 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS One. 4(2)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 4

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene.2009

    • Author(s)
      Higashikawa A, Ikeda T, et al
    • Journal Title

      Arthritis Rheum. 60

      Pages: 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Journal Article] C/EBPbeta Promotes Transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57.2009

    • Author(s)
      Hireta M, Ikeda T, et al.
    • Journal Title

      PLoS One 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Journal Article] Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages: 1065-1075

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Ikeda T, Chung U, Kawaguchi H (その他9名)
    • Journal Title

      Arthritis Rheum 60

      Pages: 166-78

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Ikeda T, Chung U, Kawaguchi H(その他5名)
    • Journal Title

      Osteoarthritis Cartilage, E-pub

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 60(1)

      Pages: 166-78

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, et.al.
    • Journal Title

      Arthritis Rheum. 60(1)

      Pages: 166-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, et.al.
    • Journal Title

      Arthritis Rheum. 60(11)

      Pages: 3314-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages: 3314-3323

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Ogasawara T, Ikeda T, et.al
    • Journal Title

      PLoS One. 4(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, et.al.
    • Journal Title

      PLoS One. 4(2)(Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Screening of chondrogenic factors with a real-time fluoresce nce-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Ogasawara T., et.al
    • Journal Title

      Arthritis Rheum. Nov ; 60(11)

      Pages: 3314-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume: 60 Pages: 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum. 60(11)

      Pages: 3314-23

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPβpromotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE

      Volume: 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of2009

    • Author(s)
      Hirata M, Ikeda T, Chung U, Kawaguchi H(その他9名)
    • Journal Title

      PLoS ONE 4

      Pages: 57-57

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages: 166-178

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, et.al.
    • Journal Title

      J Clin Invest. 118(7), Erratum in 118(8)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Clin Invest 118

      Pages: 2506-2515

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patchedl haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI.
    • Journal Title

      Dev Cell. 14(5)

      Pages: 689-99

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem 283

      Pages: 24682-24689

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, et.al.
    • Journal Title

      Dev Cell. 14(5)

      Pages: 689-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis2008

    • Author(s)
      Oshima Y, Akiyama T, Hikita A, Iwasawa M, Nagase Y, Nakamura M, Wakeyama H, Kawamura N, Ikeda T, Chung UI, Hennighausen L, Kawaguchi H, Nakamura K, Tanaka S
    • Journal Title

      J Biol Chem 283

      Pages: 26499-26508

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator2008

    • Author(s)
      Tamiya H, Ikeda T, Jeong JH, Saito T, et.al.
    • Journal Title

      Gene. 416(1-2)(Epub)

      Pages: 53-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      J Clin Invest. 118(7)

      Pages: 2506-15

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcriptional activator2008

    • Author(s)
      Tamiya H, Ikeda T, Jung JH, Saito T, Jung YK, Kawaguchi H, Ohba S, Chung UI, Choi JY
    • Journal Title

      Gene 416

      Pages: 53-60

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Ikeda T, Chung U, Kawaguchi H (その他11名)
    • Journal Title

      Dev Cell 14

      Pages: 689-99

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI
    • Journal Title

      Dev Cell 14

      Pages: 689-699

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Ikeda T, Chung U, KawaguchiH (その他14名)
    • Journal Title

      J Clin Invest 118

      Pages: 2506-15

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      J Biol Chem. 283(36)

      Pages: 24682-9

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T.
    • Journal Title

      Biochem Biophys Res Com in press

    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Saito T, et.al.
    • Journal Title

      Biochem Biophys Res Commun. 357(2)(Epub)

      Pages: 383-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, et.al.
    • Journal Title

      PLoS One. 2(10)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T.
    • Journal Title

      Biochem Biophys Res Com (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor2007

    • Author(s)
      Ohba S, Ikeda T, Kugimiya F, Yano F, Lichtler AC, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Journal Title

      FASEB J 21

      Pages: 1777-1787

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, et.al.
    • Journal Title

      EMBO Rep. 8(5)(Epub)

      Pages: 504-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Identification and Characterization of the human SOX6 promoter.2007

    • Author(s)
      Toshiyuki Ikeda, et. al.
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 383-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 383-390

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor2007

    • Author(s)
      Ohba S, Ikeda T, Kugimiya F, Yano F, Lichtler AC, Nakamura K, Takato T, Kawaguchi H, Chung UI.
    • Journal Title

      FASEB J. 21(8)

      Pages: 1777-87

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Aktl in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS One. 2(10)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Tobe T, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE 2(10)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      EMBO Rep. 8(5)

      Pages: 504-9

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] S100A1 and B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      EMBO Rep 8

      Pages: 504-509

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification and characterization of the human SOX_6 promoter2007

    • Author(s)
      Ikeda T, Chung U, Kawaguchi H (その他7名)
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages: 383-90

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Carminerin contributes to chondrocyte calcification during endochondral ossification2006

    • Author(s)
      Yamada T, Kawano H, Koshizuka Y, Fukuda T, Yoshimura K, Kamekura S, Saito T, Ikeda T, Kawasaki Y, Azuma Y, Ikegawa S, Hoshi K, Chung UI, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      Nat Med. 12(6)

      Pages: 665-70

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Regulation of Bone Formation by Adiponectin Through Autocrine/Paracrine and Endocrine Pathways.2006

    • Author(s)
      Yusuke Shinoda, Masayuki Yamaguchi, Naoshi Ogata, Toru Akune, Naoto Kubota, Toshimasa Yamauchi, Yasuo Terauchi, Takashi Kadowaki, Yasuhiro Takeuchi, Seiji Fukumoto, Toshiyuki Ikeda, Kazuto Hoshi, Ung-il Chung, Kozo Nakamura, Hiroshi Kawaguchi
    • Journal Title

      Journal of Cellular Biochemistry 99

      Pages: 196-196

    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways2006

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H.
    • Journal Title

      J Cell Biochem 99(1)

      Pages: 196-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism (23)

      Pages: 337-340

    • NAID

      10017133178

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation.2005

    • Author(s)
      Ikeda T, Kawaguchi H, Kamekura S, Ogata N, Mori Y, Nakamura K, Ikegawa S, Chung U.
    • Journal Title

      J Bone Miner Metab 23

      Pages: 337-340

    • NAID

      10017133178

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5,Sox6,and Sox9 in different stages of chondrogenic differentiation.2005

    • Author(s)
      Ikeda T, Kawaguchi H, Kamekura S, Ogata N, Mori Y, Chung U
    • Journal Title

      J Bone Miner Metab 338

      Pages: 872-879

    • NAID

      10017133178

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages: 337-340

    • NAID

      10017133178

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages: 337-340

    • NAID

      10017133178

    • Data Source
      KAKENHI-PROJECT-16659399
  • [Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005

    • Author(s)
      Yano F, Kugiyama F, Ohba S, Ikeda T, Chikuda H, Chung U
    • Journal Title

      Biochem Biophys Res Commun 333(4)

      Pages: 1300-1308

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda Tら
    • Journal Title

      J Bone Miner Metab 23

      Pages: 337-340

    • NAID

      10017133178

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5,Sox6,and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages: 337-340

    • NAID

      10017133178

    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005

    • Author(s)
      Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung U.
    • Journal Title

      Biochem Biophys Res Commun 333(4)

      Pages: 1300-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages: 337-340

    • NAID

      10017133178

    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] The combination of SOX5, SOX6 and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kawano H, Sekine K, Matsumoto T, Fukuda T, Azuma Y, Chung U, Chambon P, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] 骨・軟骨分化決定因子の解析から再生医学へ2004

    • Author(s)
      鄭 雄一, 池田敏之, 川口 浩, 中村耕三, 高戸 毅
    • Journal Title

      分子リウマチ 2

      Pages: 22-26

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9(the SOX trio)provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kamekura S, Kawaguchi H, Ikegawa S, Chung U
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.2004

    • Author(s)
      Chikuda H, Kugimiya F, Ikeda T, Ogasawara T, Shimoaka T, Kawano H, Kamekura S, Tsuchida A, Yokoi N, Nakamura K, Komeda K, Chung U, Kawaguchi H.
    • Journal Title

      Genes Dev 18

      Pages: 2418-2429

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage2004

    • Author(s)
      Ikeda, T
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] The combination of SOX5, SOX6 and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kamekura S, Mabuchi A, Kou I, Seki S, Takato T, Nakamura K, Kawaguchi H, Ikegawa S, Chung U.
    • Journal Title

      Arthritis Rheum 50

      Pages: 3561-3573

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes2004

    • Author(s)
      Chikuda H, Kugimiya F, Ikeda T, Komeda K, Chung U
    • Journal Title

      Genes Dev 18

      Pages: 2418-2429

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage2004

    • Author(s)
      Ikeda, T
    • Journal Title

      Arthritis Rheum (50)

      Pages: 3561-3573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda T
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Title : Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system

    • Author(s)
      Hojo H, Yano F, Ohba S, Igawa K, Nakajima K, Komiyama Y, Kan A, Ikeda T, Yonezawa T, Woo JT, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      J Bone Miner Metab (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda T et al.
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF2A during skeletal growth and osteoarthritis development

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
    • Journal Title

      Nature Med (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification and characterization of the human SOX6 promoter.

    • Author(s)
      Toshiyuki Ikeda, et al.
    • Journal Title

      Biochem Biophys Res Commun (印刷中)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda T
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda, T
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H.
    • Journal Title

      Nat Med (in press)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] 自己血貯血時のエクセルを用いた半電子式クリニカルパス導入は貯血時の貧血コントロールに有用である2019

    • Author(s)
      白澤知恵、関口ひろみ、寺田類、山崎翔、池田敏之、岡崎仁
    • Organizer
      第32回自己血輸血学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Presentation] 内頸静脈の心拍変動は、貯血による血行動態の変化を捉え、貯血後身体症状出現リスクの予測因子となりうるか?2018

    • Author(s)
      寺田類、池田敏之、宇仁暢大、山崎翔、張成虎、石井一彦、徳永蔵人、中村謙介、飛田明子、富岡悠二、小林英津子、岡崎仁
    • Organizer
      第66回日本輸血・細胞治療学会総会
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Presentation] 母親血清中のセルフリーDNAを用いたHPA-4b不適合妊娠患者の出生前DNAタイピング法の検討2018

    • Author(s)
      中村潤子、池田敏之、寺田類、川端みちる、名倉豊、曽根伸治、松橋美佳、岡崎仁
    • Organizer
      第66回日本輸血・細胞治療学会総会
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Presentation] WeakD/Delを引き起こすエクソンスキッピングのメカニズムと蛋白発現への影響2017

    • Author(s)
      三島由祐子, 池田敏之, 佐藤智彦, 正本庸介, 名倉豊, 曽根伸治, 岡崎仁
    • Organizer
      第64回 日本輸血・細胞治療学会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2017-04-28
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Presentation] 脳神経外科手術における自己血輸血の安全性・有効性 その12016

    • Author(s)
      高柳俊作、池田敏之 他
    • Organizer
      日本自己血輸血学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-11
    • Data Source
      KAKENHI-PROJECT-25462358
  • [Presentation] 脳神経外科手術における自己血輸血の安全性・有効性 その22016

    • Author(s)
      川端みちる、池田敏之 他
    • Organizer
      日本自己血輸血学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-11
    • Data Source
      KAKENHI-PROJECT-25462358
  • [Presentation] Identification and characterization of molecular basis of Del mutations in the Japanese population2015

    • Author(s)
      Mishima Y, Sato T, Ikeda T et al.
    • Organizer
      AABB
    • Place of Presentation
      Anaheim
    • Year and Date
      2015-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462358
  • [Presentation] A novel thienoindazole-derivative small compound induces chondrogenic differentiation without promoting hypertrophy through Runx1 (Young Investigator Award)2009

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Hojo H, Kimura A, Takeda S, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during osteophyte foration in osteoarthritis2009

    • Author(s)
      Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression2009

    • Author(s)
      Saito T, Fukai A, Ikeda T, Yano F, Hirata M, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] NF-kappa B family member RelA/p65, a transcription factor of Sox9, is essential for chondrogenic differentiation and skeletal growth (Young Investigator Award)2009

    • Author(s)
      Itoh S, Saito T, Ushita M, Ikeda T, Yano F, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] β-catenin directly binds to a specifc intracellular domain of PTH/PTHrP receptor and regulates the signaling in chondrocytes during endochondral ossification. (President's Award)2008

    • Author(s)
      Yano F, Chung UI, Ikeda T, Kawasaki Y, Kawaguchi H, Tawfeek HAW, Mahon MJ, Segre GV, Ogata N
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of a transcription factor p63 for transactivation of Wnt9a and Gdf5 causing joint cartilage formation2008

    • Author(s)
      Kan A, Ikeda T, Saito T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Hypoxia-inducible factor 2A (HIF2A) controls sequential steps in the late stage of endochondral ossification (Young Investigator Award)2008

    • Author(s)
      Saito T, Ikeda T, Kan A, Hirata M, Fukai A, Yano F, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] C/EBP-beta promotes hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2> during endochonderal ossification (Young Investigator Award)2008

    • Author(s)
      Kugimiya F, Hirata M, Ohba S, Kawamura K, Ogasawara T, Kawasaki Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] A Novel small thienoindazole-derivative compound promotes chondrogenic differentiation without inducing hypertrophy through production of Runx1 (Young Investigator Award)2008

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Development of high-throughput screening system for osteogenic drugs using cell-based sensor2008

    • Author(s)
      Hojo H, Igawa K, Ohba S, Yano F, Nakajima K, Komiyama K, Yonezawa T, Woo JT, Lichtler AC, Rowe DW, Ikeda T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] C/EBPβ/p57^<Kip2> signaling maintains transition from proliferation to hypertrophic differentiation of chondrocytes during skeletal growth2008

    • Author(s)
      Hirata M, Kugimiya F, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of type X collagen by Runx2 : Molecular network underlying chondrocyte hypertrophy causing osteoarthritis2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of a novel chondrogenic factor Sorting Nexin 19 using a real-time fluorescence monitoring cell line ATDC5-S2RD52007

    • Author(s)
      Kan A, Ikeda T, Saito T, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 Plays a Central Role in Cartilage Development by Directly Regulating Key Genes for Chondrogenesis2007

    • Author(s)
      Toshiyuki Ikeda et.al
    • Organizer
      The American Society for Bone and Mineral Research 29th Annual Meeting
    • Place of Presentation
      Hawaii,USA.
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] 新規軟骨分化転因子ZFPACはC/EBPβと協調的に作用して軟骨分化を誘導する2007

    • Author(s)
      池田 敏之
    • Organizer
      第25回日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-02
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Presentation] Runx1, co-activator of Sox5, Sox6 and Sox9 (the Sox trio) regulates chondrogenic differentiation2007

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Takeda S, Kimura A, Ohba S, Kugimiya F, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 plays a central role in cartilage development by directly regulating key genes for chondrogenesis2007

    • Author(s)
      Ikeda T, Kawaguchi H, Saito T, Kan A, Yano F, Ushita M, Kawasaki Y, Nakamura K, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 Plays a Central Role in Cartilage Development by Directly Regulating Key Genes for Chondrogenesis2007

    • Author(s)
      Tbshiyuld Ikeda
    • Organizer
      ASBMR 29thAnnual Meeting
    • Place of Presentation
      Hawah,USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] p63 Plays a Centr al Role in Cartilage Development by Directly Regulating Key Genes for Ch ondrogenesis2007

    • Author(s)
      Ikeda T, et al.
    • Organizer
      ASBMR 29^<th> Annual Meeting
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] Transcriptional induction of SOX9 by NF-κB subunit p65 during chondrogenesis2007

    • Author(s)
      Ushita M, Ikeda T, Saito T, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional induction of type X collagen expression and hypertrophic differentiation of chondrocytes by Runx2 during osteoarthritis progression (Young Investigator Award)2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63は軟骨の初期分化から後期分化までを統合的に支配するマスター転写因子である2007

    • Author(s)
      池田敏之ら
    • Organizer
      第25回日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] Hypoxia-inducible factor 2α induces type X collagen and promotes hypertrophic differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Higashikawa A, Kawasaki Y, Kan A, Ushita M, Ohba S, Yano F, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of sorting nexin 19 as a novel chondrogenic factor by a real-time fluorescence monitoring cell line ATDC5-S2RD5 (Young Investigator Award)2007

    • Author(s)
      Kan A, Ikeda T, Saito T, Ushita M, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • 1.  NAKAMURA Kozo (60126133)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 59 results
  • 2.  CHUNG Ung-Il (30345053)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 71 results
  • 3.  KAWAGUCHI Hiroshi (40282660)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 74 results
  • 4.  MATSUBARA Takehiro (40361498)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  SAITO Taku (30456107)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 57 results
  • 6.  TANAKA Sakae (50282661)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  ONISHI Isao (70311628)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MABUCHI Akihiko (80312312)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 9.  OGASAWARA Toru (20359623)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 10.  UCHIDA Shunya (50151882)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OGATA Naoshi (10361495)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 12.  筑田 博隆 (30345219)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 13.  MISHIMA Yuko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 14.  AKUNE Toru (60282662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  OKA Hiroyuki (60401064)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  HIROTA Jinso (30570733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  WATANABE Sumiyo (30422314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SUZUKI Nobuchika (90247007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  HONDA Zenitiro (70238814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KAWANO Hirotaka (20345218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  OOKUMA Tomotake (90534909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SAWADA Ryoko (30648308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  Taniguchi Yuki (80722165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HIRAOKA Hisatada (10262007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  FUKUDA Akira (90302695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  ITAKA Keishi (60292926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  MATSUDAIRA Ko (10302697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  Matsuhashi Mika (00759384)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  竹下 克志 (30262009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  坪井 寿和 (80302694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  岡崎 仁 (80261973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  正本 庸介 (30706974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  TAKAYANAGI Syunsaku
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 34.  KAWABATA Michiru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 35.  TAKETOMI Shuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  KOBAYASHI Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  KOMIYAMA Yusuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  OHBA Shinsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  矢野 文子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 40.  平田 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  下澤 達雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  柴田 茂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  乾 洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  田中 健之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  高戸 毅
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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