Kimura Kimitoshi 木村公俊

… Alternative Names

木村公俊キムラキミトシ

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Researcher Number	10807093
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定講師 2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所免疫研究部, 客員研究員
Affiliation (based on the past Project Information) *help	2024: 京都大学, 医学研究科, 特定助教 2023 – 2024: 京都大学, 医学研究科, 特定講師 2018 – 2019: 京都大学, 医学研究科, 特定病院助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator 多発性硬化症 / CRISPRスクリーニング / アルツハイマー型認知症 / ミクログリア / miRNA / エクソソーム / 個別化治療 / バイオマーカー / 自己抗体 / CD11c+ B細胞 … More / Th1細胞 / 血液浄化療法 / B細胞 / T細胞 / 個別化医療 … More Except Principal Investigator in vivoイメージング / CAR-T細胞 / 多発性硬化症 / 加齢変容性リンパ球 Less

加齢変容性リンパ球が介在する多発性硬化症の病態機序解明とその制御
- Principal Investigator
  
  福島祐二
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
中枢神経変性病態におけるミクログリアの機能制御Principal Investigator
- Principal Investigator
  
  木村公俊
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
Development of novel therapeutic approach and realization of personalized medicine in multiple sclerosisPrincipal Investigator
- Principal Investigator
  
  Kimura Kimitoshi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyoto University

All 2024 2019 2018

All Journal Article Presentation Patent

[Journal Article] Resident Memory-like CD8+ T Cells Are Involved in Chronic Inflammatory and Neurodegenerative Diseases in the CNS2024
- Author(s)
  Kimura Kimitoshi、Nishigori Ryusei、Hamatani Mio、Sawamura Masanori、Ashida Shinji、Fujii Chihiro、Takata Masaki、Lin Youwei、Sato Wakiro、Okamoto Tomoko、Kuzuya Akira、Takahashi Ryosuke、Yamamura Takashi、Kondo Takayuki
- Journal Title
  
  Neurology Neuroimmunology & Neuroinflammation
  
  Volume: 11 Issue: 1
- DOI
  10.1212/nxi.0000000000200172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] Clinical characteristics of autoimmune disorders in the central nervous system associated with myasthenia gravis2019
- Author(s)
  Kimura Kimitoshi、Okada Yoichiro、Fujii Chihiro、Komatsu Kenichi、Takahashi Ryosuke、Matsumoto Sadayuki、Kondo Takayuki
- Journal Title
  
  Journal of Neurology
  
  Volume: 266 Issue: 11 Pages: 2743-2751
- DOI
  10.1007/s00415-019-09461-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] 多発性硬化症と制御性T細胞2019
- Author(s)
  山村隆、木村公俊
- Journal Title
  
  医学のあゆみ
  
  Volume: 268 Pages: 1229-1233
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis2018
- Author(s)
  Kimura Kimitoshi、Hohjoh Hirohiko、Yamamura Takashi
- Journal Title
  
  Journal of Experimental Neuroscience
  
  Volume: 12
- DOI
  10.1177/1179069518764892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] 多発性硬化症において循環血中のエクソソームはlet-7i を介して制御性T細胞の分化を抑制する2018
- Author(s)
  木村公俊、北條浩彦、山村隆
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 70 Pages: 129-135
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] 多発性硬化症2018
- Author(s)
  木村公俊、山村隆
- Journal Title
  
  Progress in Medicine
  
  Volume: 38 Pages: 1311-1317
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] 多発性硬化症において、血中のエクソソームが制御性T細胞の分化を抑制する2018
- Author(s)
  木村公俊、北條浩彦、山村隆
- Journal Title
  
  実験医学
  
  Volume: 36 Pages: 1497-1500
- Data Source
  KAKENHI-PROJECT-18K15473
[Journal Article] Circulating exosomes cause loss of immunological balance in multiple sclerosis2018
- Author(s)
  Kimura Kimitoshi、Yamamura Takashi
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 9 Issue: 4 Pages: 209-210
- DOI
  10.1111/cen3.12474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15473
[Patent] 血液浄化療法の臨床的有効性を予測するためのデータを収集する方法2018
- Inventor(s)
  木村公俊、林幼偉、山村隆
- Industrial Property Rights Holder
  国立精神・神経医療研究センター
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-155801
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] マイクロRNAを介したエクソソームによる多発性硬化症の病態2019
- Author(s)
  木村公俊
- Organizer
  第3回Liquid Biopsy研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] Response to Plasmapheresis is Predicted by the Th1 Cell Frequency in the Blood in Multiple Sclerosis2019
- Author(s)
  Kimitoshi Kimura, Youwei Lin, Wakiro Sato, Ryosuke Takahashi, Takashi Yamamura
- Organizer
  Federation of Clinical Immunology Societies Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] Clinical and immunological efficacy of plasmapheresis in MS and NMO refractory to steroid pulse therapy2019
- Author(s)
  Youwei Lin, Kimitoshi Kimura, Yoko Yamada, Wakiro Sato, Manabu Araki, Tomoko Okamoto, Seiichi Yasuda, Takashi Yamamura, Yuji Takahashi
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] Th1 cell frequency is an accurate predictor of responders to plasmapheresis in multiple sclerosis2019
- Author(s)
  Kimitoshi Kimura, Youwei Lin, Wakiro Sato, Ryosuke Takahashi, Takashi Yamamura
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] ステロイドパルス療法で寛解不充分なMS・NMOにおける血液浄化療法の有効性と免疫学的指標2019
- Author(s)
  林幼偉、木村公俊、坪田　佳代子、佐藤和貴朗、荒木学、岡本智子、登坂　一眞、安田聖一、山村隆、高橋祐二
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] The efficacy of plasmapheresis for multiple sclerosis and neuromyelitis optica unresponsive to steroid-pulse therapy and its immunological prognostic markers2019
- Author(s)
  Youwei Lin, Kimitoshi Kimura, Kayoko Tsubota, Wakiro Sato, Manabu Araki, Tomoko Okamoto, Kazuma Tosaka, Seiichi Yasuda, Takashi Yamamura, Yuji Takahashi
- Organizer
  The Joint meeting of the 12th World Congress of International Society for Apheresis and the 40th Annual Meeting of Japanease Society for Apheresis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] 多発性硬化症におけるmiRNAを介したエクソソームの関与2018
- Author(s)
  木村公俊
- Organizer
  東京農工大学－国立精神・神経医療研究センター　第4回合同シンポジウム
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] Successful response to plasmapheresis is mediated by phenotypic change of Th1 cells in multiple sclerosis2018
- Author(s)
  Kimitoshi Kimura, Youwei Lin, Wakiro Sato, Ryosuke Takahashi, Takashi Yamamura
- Organizer
  14th International Congress of Neuroimmunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15473
[Presentation] 多発性硬化症への免疫吸着療法における、T細胞解析に基づいた個別化医療実現と作用機序解明2018
- Author(s)
  木村公俊、林幼偉、佐藤和貴郎、髙橋良輔、山村隆
- Organizer
  第30回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15473

1. 福島祐二 (90583146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 服部雅一 (40211479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kimura Kimitoshi 木村 公俊

木村 公俊 キムラ キミトシ

Research Projects

Research Products

Co-Researchers

加齢変容性リンパ球が介在する多発性硬化症の病態機序解明とその制御

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

中枢神経変性病態におけるミクログリアの機能制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutic approach and realization of personalized medicine in multiple sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Resident Memory-like CD8+ T Cells Are Involved in Chronic Inflammatory and Neurodegenerative Diseases in the CNS2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical characteristics of autoimmune disorders in the central nervous system associated with myasthenia gravis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 多発性硬化症と制御性T細胞2019

Author(s)

Journal Title

Data Source

[Journal Article] The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 多発性硬化症において循環血中のエクソソームはlet-7i を介して制御性T細胞の分化を抑制する2018

Author(s)

Journal Title

Data Source

[Journal Article] 多発性硬化症2018

Author(s)

Journal Title

Data Source

[Journal Article] 多発性硬化症において、血中のエクソソームが制御性T細胞の分化を抑制する2018

Author(s)

Journal Title

Data Source

[Journal Article] Circulating exosomes cause loss of immunological balance in multiple sclerosis2018

Author(s)

Journal Title

DOI

Data Source

[Patent] 血液浄化療法の臨床的有効性を予測するためのデータを収集する方法2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] マイクロRNAを介したエクソソームによる多発性硬化症の病態2019

Author(s)

Organizer

Data Source

[Presentation] Response to Plasmapheresis is Predicted by the Th1 Cell Frequency in the Blood in Multiple Sclerosis2019

Author(s)

Organizer

Data Source

[Presentation] Clinical and immunological efficacy of plasmapheresis in MS and NMO refractory to steroid pulse therapy2019

Author(s)

Organizer

Data Source

[Presentation] Th1 cell frequency is an accurate predictor of responders to plasmapheresis in multiple sclerosis2019

Author(s)

Kimura Kimitoshi 木村公俊

木村公俊キムラキミトシ