AOYAGI Hiroaki 青柳浩明

Researcher Number	10814501
Affiliation (based on the past Project Information) *help	2018 – 2022: 岡山大学, 歯学部, 客員研究員 2017: 岡山大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology
Keywords	Principal Investigator M1マクロファージ / 幹細胞 / HMGB1 / 血管 / 歯周病 / 血管内皮細胞由来のHMGB1 / 全身疾患 / マクロファージ / 歯周炎 / 創傷治癒 … More / 低栄養 / 骨再生 / 血管新生 / 骨治癒 / 免疫細胞 / 炎症 / 抜歯 / 抜歯窩創傷治癒 … More Except Principal Investigator マクロファージ / HMGB1 / 歯周病 / 炎症 / 幹細胞 / 創傷治癒 / 低栄養 / 遺伝子 / 免疫学 / 歯学 / 抗体療法 / 炎症性サイトカイン / 歯周炎 / 好中球 / 歯肉上皮細胞 / サイトカイン Less

The effects of HMGB1 produced by vascular endothelial cells in periodontal tissue on systemic diseases.Principal Investigator
- Principal Investigator
  
  AOYAGI HIROAKI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Malnutrition delayed wound healing by HMGB1-related prolonged inflammation
- Principal Investigator
  
  Yamashiro Keisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kobe Tokiwa Junior College
  Okayama University
A novel tissue regeneration treatment applying the angiogensis and stem cell migration by HMGB1Principal Investigator
- Principal Investigator
  
  AOYAGI HIROAKI
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Functional analysis of HMGB1 as an inflammatory mediator in periodontitis
- Principal Investigator
  
  YAMASHIRO KEISUKE
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Okayama University

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Malnutrition delayed wound healing after tooth extraction by HMGB1-related prolonged inflammation2021
- Author(s)
  Yao Zhang, Hidetaka Ideguchi, Hiroaki Aoyagi, Keisuke Yamashiro, Tadashi Yamamoto, Masahiro Nishibori, Shogo Takashiba
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 96 Pages: 107772-107772
- DOI
  10.1016/j.intimp.2021.107772
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K23054
[Journal Article] High Mobility Group Box 1 Expression in Oral Inflammation and Regeneration2020
- Author(s)
  Keisuke Yamashiro, Hidetaka Ideguchi, Hiroaki Aoyagi, Chiaki Yoshihara-Hirata, Anna Hirai, Risa Suzuki-Kyoshima, Yao Zhang, Hidenori Wake, Masahiro Nishibori, Tadashi Yamamoto, ShogoTakashiba
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1461-1461
- DOI
  10.3389/fimmu.2020.01461
- NAID
  120006880201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-20K23054
[Journal Article] Molecular imaging assessment of periodontitis lesions in an experimental mouse model2019
- Author(s)
  Ideguchi Hidetaka，Yamashiro Keisuke，Yamamoto Tadashi，Shimoe Masayuki，Hongo Shoichi，Kochi Shinsuke，Yoshihara-Hirata Chiaki，Aoyagi Hiroaki，Kawamura Mari，Takashiba Shogo
- Journal Title
  
  Clinical Oral Investigations
  
  Volume: 23 Issue: 2 Pages: 821-827
- DOI
  10.1007/s00784-018-2510-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17050
[Journal Article] Induction of migration of periodontal ligament cells by selective regulation of integrin subunits2019
- Author(s)
  Kawamura Mari，Yamamoto Tadashi，Yamashiro Keisuke，Kochi Shinsuke，Yoshihara‐Hirata Chiaki，Ideguchi Hidetaka，Aoyagi Hiroaki，Omori Kazuhiro，Takashiba Shogo .
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 23 Issue: 2 Pages: 1211-1223
- DOI
  10.1111/jcmm.14023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17050
[Journal Article] HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket2018
- Author(s)
  Aoyagi Hiroaki、Yamashiro Keisuke、Hirata-Yoshihara Chiaki、Ideguchi Hidetaka、Yamasaki Mutsuyo、Kawamura Mari、Yamamoto Tadashi、Kochi Shinsuke、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: - Issue: 7 Pages: 5481-5490
- DOI
  10.1002/jcb.26710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050
[Journal Article] Anti-HMGB1 Neutralizing Antibody Attenuates Periodontal Inflammation and Bone Resorption in a Murine Periodontitis Model2018
- Author(s)
  Yoshihara-Hirata Chiaki、Yamashiro Keisuke、Yamamoto Tadashi、Aoyagi Hiroaki、Ideguchi Hidetaka、Kawamura Mari、Suzuki Risa、Ono Mitsuaki、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
- Journal Title
  
  Infection and Immunity
  
  Volume: 86 Issue: 5
- DOI
  10.1128/iai.00111-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050, KAKENHI-PROJECT-16K11624
[Presentation] HMGB1はマクロファージをM1タイプに極性化させて歯周炎の進行に影響を及ぼす2021
- Author(s)
  平井杏奈，井手口英隆，山城圭介，青柳浩明，山本直史，高柴正悟
- Organizer
  春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K18535
[Presentation] HMGB1はM１マクロファージの分化を制御して歯周炎の進行に影響を及ぼす2021
- Author(s)
  平井杏奈，井手口英隆，山城圭介，Zhang Yao，青柳浩明，山本直史，高柴正悟
- Organizer
  第64回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-20K18535
[Presentation] Delayed Wound Healing after Tooth Extraction under Malnutrition2020
- Author(s)
  Y. ZHANG, H. IDEGUCHI, H. AOYAGI, K. YAMASHIRO, T. YAMAMOTO, M. NISHIBORI, S. TAKASHIBA
- Organizer
  Japanese Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10128
[Presentation] HMGB1-induced inflammatory response promotes bone regeneration in murine tooth socket2018
- Author(s)
  Hiroaki Aoyagi，Keisuke Yamashiro，Chiaki Hirata-Yoshihara，Hidetaka Ideguchi，Mari Kawamura，Hidenori Wake，Mutsuyo Yamasaki，Risa Suzuki，Shinsuke Kochi，Tadashi Yamamoto，Masahiro Nishibori and Shogo Takashiba
- Organizer
  IADR/APR General Session & Exhibition
- Data Source
  KAKENHI-PROJECT-18K17050
[Presentation] 炎症性メディエーターHMGB1が歯槽骨治癒における血管新生の遺伝子発現を促進する2017
- Author(s)
  青柳浩明，山城圭介，吉原千暁，井手口英隆，山本直史，河村麻理，下江正幸，本郷昌一，劉克約，西堀正洋，高柴正悟
- Organizer
  第38回炎症再生医学会
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] HMGB1が歯槽骨治癒に及ぼす影響2017
- Author(s)
  青柳浩明，山城圭介，吉原千暁，井手口英隆，山本直史，河村麻理，下江正幸，高柴正悟
- Organizer
  第60回日本歯周病学会
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] Anti-HMGB1 neutralizing antibody attenuates cytokine secretion and progression of periodontitis2016
- Author(s)
  C. YOSHIHARA，K. YAMASHIRO，T. YAMAMOTO，H. IDEGUCHI，H. AOYAGI，M. SHIMOE，S. HONGO，M. KAWAMURA，K. Liu，M. NISHIBORI，S. TAKASHIBA，
- Organizer
  IADR/APR General Session & Exhibition
- Place of Presentation
  COEX Convention Center, Korea, Seoul
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] 実験的歯周炎モデルマウスにおける抗HMGB1抗体の歯周炎抑制効果2016
- Author(s)
  吉原千暁，山城圭介，山本直史，井手口英隆，青柳浩明，下江正幸，本郷昌一，河村麻理，高柴正悟
- Organizer
  第59回春季日本歯周病学会
- Place of Presentation
  かごしま県民交流センター，鹿児島市
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-16K20670

1. YAMASHIRO KEISUKE (30581087)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. NISHIBORI Masahiro (50135943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. IDEGUCHI Hidetaka (80779421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. KOCHI Shinsuke (70803138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMAMOTO Tadashi (50432662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. WAKE Hidenori (60570520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宝田剛志 (30377428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AOYAGI Hiroaki 青柳 浩明

Research Projects

Research Products

Co-Researchers

The effects of HMGB1 produced by vascular endothelial cells in periodontal tissue on systemic diseases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Malnutrition delayed wound healing by HMGB1-related prolonged inflammation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel tissue regeneration treatment applying the angiogensis and stem cell migration by HMGB1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of HMGB1 as an inflammatory mediator in periodontitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Malnutrition delayed wound healing after tooth extraction by HMGB1-related prolonged inflammation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High Mobility Group Box 1 Expression in Oral Inflammation and Regeneration2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Molecular imaging assessment of periodontitis lesions in an experimental mouse model2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of migration of periodontal ligament cells by selective regulation of integrin subunits2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-HMGB1 Neutralizing Antibody Attenuates Periodontal Inflammation and Bone Resorption in a Murine Periodontitis Model2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] HMGB1はマクロファージをM1タイプに極性化させて 歯周炎の進行に影響を及ぼす2021

Author(s)

Organizer

Data Source

[Presentation] HMGB1はM１マクロファージの分化を制御して歯周炎の進行に影響を及ぼす2021

Author(s)

Organizer

Data Source

[Presentation] Delayed Wound Healing after Tooth Extraction under Malnutrition2020

Author(s)

Organizer

Data Source

[Presentation] HMGB1-induced inflammatory response promotes bone regeneration in murine tooth socket2018

Author(s)

Organizer

Data Source

[Presentation] 炎症性メディエーターHMGB1が歯槽骨治癒における血管新生の遺伝子発現を促進する2017

Author(s)

Organizer

Data Source

[Presentation] HMGB1が歯槽骨治癒に及ぼす影響2017

AOYAGI Hiroaki 青柳浩明

[Presentation] HMGB1はマクロファージをM1タイプに極性化させて歯周炎の進行に影響を及ぼす2021