Yamashiro Keisuke 山城圭介

… Alternative Names

Researcher Number	30581087
Other IDs	https://orcid.org/0000-0003-1208-892X
Affiliation (Current)	2022: 神戸常盤大学短期大学部, 口腔保健学科, 教授
Affiliation (based on the past Project Information) *help	2019 – 2020: 岡山大学, 大学病院, 講師 2016 – 2018: 岡山大学, 医歯薬学総合研究科, 助教 2014: 岡山大学, 医歯薬学総合研究科, 助教 2011 – 2014: 岡山大学, 医歯(薬)学総合研究科, 助教 2013: 岡山大学, 大学院医歯薬学総合研究科, 助教 2010 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Periodontal dentistry / Periodontology / Basic Section 57030:Conservative dentistry-related Except Principal Investigator Periodontal dentistry / Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 歯肉上皮細胞 / TGF-β / 細胞接着 / 炎症 / HMGB1 / マクロファージ / インテグリン / 細胞外基質 / Smad2 / Aggregatibacter actinomycetemcomitans … More Except Principal Investigator 歯周組織 / 歯根膜 / 細胞分化 / RhoA-ROCKシグナル / Y-27632 / 遺伝子導入 / 遺伝子発現 / RhoA / ROCK / Rho / Rho-kinase / ストレスファイバー / 感染 / 顎骨壊死 / BP製剤 / 口内炎 / 細胞周期 / 細胞増殖・分化 / 歯周病 / 歯周病原細菌 / ペプチド核酸 / アンチセンス / キャリアーペプチド / アンチセンス医療 / インテグリン / 細胞外基質 / 増殖因子 / 微小環境 / 幹細胞 / 歯周組織再生 / 炎症性老化 / サルコペニア / 慢性炎症 / 歯周炎 / IL-6 / 糖尿病 / Vital pulp therapy / Resolvin D2 (RVD2) / Dentin regeneration / pulp capping / lipid mediator Less

APPLICATION OF RvD2 AS A REGENERATIVE DIRECT PULP CAPPING MATERIAL
- Principal Investigator
  
  アリアス・マルティネススレマ・ロサリア
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
低栄養時の炎症の遷延化，創傷治癒遅延のメカニズム解明：HMGB1機能不全の可能性Principal Investigator
- Principal Investigator
  
  山城圭介
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Investigation of integrin peptide therapy regulating stem cell niche for periodontal regeneration
- Principal Investigator
  
  Yamamoto Tadashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Elucidation of pathology of periodontal disease, sarcopenia, and diabetes centered on inflammation-aging
- Principal Investigator
  
  Kobayashi Hiroya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Functional analysis of HMGB1 as an inflammatory mediator in periodontitisPrincipal Investigator
- Principal Investigator
  
  YAMASHIRO KEISUKE
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Okayama University
Application of antisense PNA as antibiotics against periodontal pathogens
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
  Okayama University
歯肉上皮細胞におけるＴＧＦ－βによる細胞接着因子制御の分子生物学的解明Principal Investigator
- Principal Investigator
  
  山城圭介
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Construction of the prevention system of a Bisphosphonate-Related Osteonecrosis of the Jaw judging from an intraoral infection degree
- Principal Investigator
  
  HATANAKA KAZU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Cell cycle atlas of periodontium
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
The molecular biological analysis of the mechanism for cell adhesion mediated by growth factor in human gingival epithelial cellsPrincipal Investigator
- Principal Investigator
  
  YAMASHIRO Keisuke
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Investigation of the mechanisms of osteogenic differentiation by RhoA in periodontal ligament cells for cell transplantation
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University

All 2020 2018 2017 2016 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] High Mobility Group Box 1 Expression in Oral Inflammation and Regeneration2020
- Author(s)
  Keisuke Yamashiro, Hidetaka Ideguchi, Hiroaki Aoyagi, Chiaki Yoshihara-Hirata, Anna Hirai, Risa Suzuki-Kyoshima, Yao Zhang, Hidenori Wake, Masahiro Nishibori, Tadashi Yamamoto, ShogoTakashiba
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1461-1461
- DOI
  10.3389/fimmu.2020.01461
- NAID
  120006880201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10128, KAKENHI-PROJECT-20K23054
[Journal Article] Anti-HMGB1 neutralizing antibody attenuates periodontal inflammation and bone resorption in a murine periodontitis model.2018
- Author(s)
  Yoshihara-Hirata Chiaki、Yamashiro Keisuke、Yamamoto Tadashi、Aoyagi Hiroaki、Ideguchi Hidetaka、Kawamura Mari、Suzuki Risa、Ono Mitsuaki、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
- Journal Title
  
  Infect Immun.
  
  Volume: 86
- DOI
  10.1128/iai.00111-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050, KAKENHI-PROJECT-16K11624
[Journal Article] HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket.2018
- Author(s)
  Aoyagi Hiroaki、Yamashiro Keisuke、Hirata-Yoshihara Chiaki、Ideguchi Hidetaka、Yamasaki Mutsuyo、Kawamura Mari、Yamamoto Tadashi、Kochi Shinsuke、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: - Pages: 5481-5490
- DOI
  10.1002/jcb.26710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050
[Journal Article] Overexpression of Smad2 Inhibits Proliferation of Gingival Epithelial Cells2014
- Author(s)
  Shimoe M, Yamamoto T, Shiomi N, Tomikawa K, Hongo S, Yamashiro K, Yamaguchi T, Maeda H, Takashiba S
- Journal Title
  
  J Periodontal Res
  
  Volume: 49(3) Pages: 290-8
- DOI
  10.1111/jre.12106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659977
[Journal Article] Overexpression of Smad2 Inhibits Proliferation of Gingival Epithelial Cells2013
- Author(s)
  Masayuki Shimoe, Tadashi Yamamoto, Nobuyuki Shiomi, Kazuya Tomikawa, Shoichi Hongo, Keisuke Yamashiro, Tomoko Yamaguchi, Hiroshi Maeda, Shogo Takashiba
- Journal Title
  
  Journal of periodontal research
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24792327
[Journal Article] Smad2 Decelerates Re-epithelialization during Gingival Wound Healing2012
- Author(s)
  Tomikawa Kazuya
- Journal Title
  
  Journal of Dental Research
  
  Volume: 91 Pages: 764-70
- DOI
  10.1177/0022034512451449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890128, KAKENHI-PROJECT-24792327
[Presentation] Delayed Wound Healing after Tooth Extraction under Malnutrition2020
- Author(s)
  Y. ZHANG, H. IDEGUCHI, H. AOYAGI, K. YAMASHIRO, T. YAMAMOTO, M. NISHIBORI, S. TAKASHIBA
- Organizer
  Japanese Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10128
[Presentation] インテグリンα3の選択的阻害による微小環境の構築と歯槽骨再生2020
- Author(s)
  森彩乃，山本直史，河村麻理，井手口英隆，青柳浩明，中村心，岡本憲太郎，平井杏奈，山城圭介，大森一弘，高柴正悟
- Organizer
  日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-18K09576
[Presentation] 炎症性メディエーターHMGB1が歯槽骨治癒における血管新生の遺伝子発現を促進する2017
- Author(s)
  青柳浩明，山城圭介，吉原千暁，井手口英隆，山本直史，河村麻理，下江正幸，本郷昌一，劉克約，西堀正洋，高柴正悟
- Organizer
  第38回炎症再生医学会
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] HMGB1が歯槽骨治癒に及ぼす影響2017
- Author(s)
  青柳浩明，山城圭介，吉原千暁，井手口英隆，山本直史，河村麻理，下江正幸，高柴正悟
- Organizer
  第60回日本歯周病学会
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] 実験的歯周炎モデルマウスにおける抗HMGB1抗体の歯周炎抑制効果2016
- Author(s)
  吉原千暁，山城圭介，山本直史，井手口英隆，青柳浩明，下江正幸，本郷昌一，河村麻理，高柴正悟
- Organizer
  第59回春季日本歯周病学会
- Place of Presentation
  かごしま県民交流センター，鹿児島市
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] Anti-HMGB1 neutralizing antibody attenuates cytokine secretion and progression of periodontitis2016
- Author(s)
  C. YOSHIHARA，K. YAMASHIRO，T. YAMAMOTO，H. IDEGUCHI，H. AOYAGI，M. SHIMOE，S. HONGO，M. KAWAMURA，K. Liu，M. NISHIBORI，S. TAKASHIBA，
- Organizer
  IADR/APR General Session & Exhibition
- Place of Presentation
  COEX Convention Center, Korea, Seoul
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20670
[Presentation] グリチルリチン酸経口投与によるin vivo 歯周組織治癒効果2014
- Author(s)
  井手口英隆,山城圭介,山本直史,本郷昌,下江正幸,高知信介,青柳浩明,吉原千暁,河村麻里,前田博史,高柴正悟
- Organizer
  第57回日本歯周病学会春季学術大会
- Place of Presentation
  岐阜
- Year and Date
  2014-05-23
- Data Source
  KAKENHI-PROJECT-23659977
[Presentation] グリチルリチン酸経口投与によるin vivo歯周組織治癒効果2014
- Author(s)
  井手口英隆，山城圭介，山本直史，本郷昌一，下江正幸，高知信介，青柳浩明，吉原千暁，河村麻里，前田博史，高柴正悟
- Organizer
  第57回日本歯周病学会春季学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-23659977
[Presentation] 外来化学療法中の患者における口内炎発症の実態と今後の課題について2013
- Author(s)
  高坂由紀奈、杉浦裕子、小倉早紀、三浦留美、山城圭介、宮脇卓也、田端雅弘
- Organizer
  岡山歯学会総会・学術集会
- Place of Presentation
  岡山市
- Year and Date
  2013-10-27
- Data Source
  KAKENHI-PROJECT-23593058
[Presentation] 外来化学療法中の患者における口内炎発症の実態と今後の課題について2013
- Author(s)
  高坂由紀奈，杉浦裕子，小倉早妃，三浦留美，山城圭介，宮脇卓也，田端雅弘
- Organizer
  岡山歯学会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-23593058
[Presentation] 歯肉上皮においてSmad2はintegrin発現を促進する2013
- Author(s)
  本郷昌一，山城圭介，山本直史，高知信介，下江正幸，冨川和哉，鵜川祐樹，前田博史，高柴正悟
- Organizer
  138回　日本歯科保存学会
- Place of Presentation
  博多市
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] Aggregatibacter actinomycetemcomitans Y4はintegrin α5を介して細胞内に侵入する2013
- Author(s)
  高知信介，山城圭介，山本直史，下江正幸，本郷昌一，冨川和哉，鵜川祐樹，前田博史，高柴正悟
- Organizer
  第56回秋季日本歯周病学会
- Place of Presentation
  前橋市
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] 歯肉上皮細胞において外因性Smad2は細胞接着分子の発現を促進する2011
- Author(s)
  本郷昌一, 山城圭介
- Organizer
  第54回秋季日本歯周病学会
- Place of Presentation
  山口県下関市
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22890119
[Presentation] Aggregatibacter actinomycetemcomitansがヒト歯肉上皮細胞の細胞接着因子に及ぼす影響2011
- Author(s)
  高知信介, 山城圭介
- Organizer
  平成23年度秋季日本歯科保存学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22890119
[Presentation] 歯根膜線維芽細胞においてSmad2はFGF2遺伝子発現を促進する
- Author(s)
  鵜川祐樹，山本直史，山城圭介，下江正幸，冨川和哉，本郷昌一，高知信介，前田博史，高柴正悟
- Organizer
  第137回日本歯科保存学会秋季大会
- Place of Presentation
  広島県広島市
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] Integrin α5 Regulates Cell Adhesion in Gingival Epithelium during Infection
- Author(s)
  S. KOCHI, K. YAMASHIRO, T. YAMAMOTO, S. HONGO, M. SHIMOE, K. TOMIKAWA, Y. UGAWA, H. MAEDA, S. TAKASHIBA
- Organizer
  91th International Association for Dental Research
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] Overexpression of Smad2 Enhances FGF2 Expression in Periodontal Ligament Cells
- Author(s)
  Y. UGAWA, T. YAMAMOTO, K. YAMASHIRO, S. HONGO, H. IDEGUCHI, M. SHIMOE, K. TOMIKAWA, S. KOCHI, H. MAEDA, S. TAKASHIBA
- Organizer
  91th International Association for Dental Research
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] Aggregatibacter actinomycetemcomitansおよび抗菌薬添加がヒト歯肉上皮細胞の細胞接着因子に及ぼす影響
- Author(s)
  高知信介，山城圭介, 山本直史，本郷昌一, 下江正幸，冨川和哉，鵜川祐樹，前田博史，高柴正悟
- Organizer
  第136回日本歯科保存学会春季大会
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] 歯肉上皮細胞においてSmad2/3は細胞接着分子と細胞外基質の発現を促進する
- Author(s)
  本郷昌一，山城圭介，山本直史，高知信介，下江正幸，冨川和哉，鵜川祐樹，前田博史，高柴正悟
- Organizer
  第55回日本歯周病学会春季学術大会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-24792327
[Presentation] TGF-β Signaling Enhances Cell Adhesion in Gingival Epithelial Cells
- Author(s)
  S. Hongo, K. Yamashiro, T. Yamamoto, S. Kochi, M. Shimoe, K. Tomikawa, Y. Ugawa, H. Maeda, S. Takashiba
- Organizer
  91th International Association for Dental Research
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-24792327

1. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 9 results

# of Collaborated Products: 10 results
2. YAMAMOTO Tadashi (50432662)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
3. HATANAKA KAZU (50362992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. AOYAGI Hiroaki (10814501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. NISHIBORI Masahiro (50135943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. Kobayashi Hiroya (20710651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MINESHIBA Junji (00509383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NARUISHI Koji (00346446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIOMI Nobuyuki (90432632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SONOYAMA Wataru (40325121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAGUCHI Tomoko (90580267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. MAEDA Hiroshi (00274001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOKEGUCHI Susumu (10144776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KITAMATSU Mizuki (60379716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MINESHIBA Fumi (90346461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IDEGUCHI Hidetaka (80779421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
17. KOCHI Shinsuke (70803138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. WAKE Hidenori (60570520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 宝田剛志 (30377428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. アリアス・マルティネススレマ・ロサリア (70824580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 大森一弘 (20549860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ISOSHIMA Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TOMIKAWA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. KIMURA Aya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 大野充昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashiro Keisuke 山城 圭介

YAMASHIRO KEISUKE 山城 圭介

YAMASHIRO Keisuke 山城 圭介

Research Projects

Research Products

Co-Researchers

APPLICATION OF RvD2 AS A REGENERATIVE DIRECT PULP CAPPING MATERIAL

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低栄養時の炎症の遷延化，創傷治癒遅延のメカニズム解明：HMGB1機能不全の可能性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of integrin peptide therapy regulating stem cell niche for periodontal regeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathology of periodontal disease, sarcopenia, and diabetes centered on inflammation-aging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of HMGB1 as an inflammatory mediator in periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of antisense PNA as antibiotics against periodontal pathogens

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

歯肉上皮細胞におけるＴＧＦ－βによる細胞接着因子制御の分子生物学的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of the prevention system of a Bisphosphonate-Related Osteonecrosis of the Jaw judging from an intraoral infection degree

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell cycle atlas of periodontium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular biological analysis of the mechanism for cell adhesion mediated by growth factor in human gingival epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanisms of osteogenic differentiation by RhoA in periodontal ligament cells for cell transplantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] High Mobility Group Box 1 Expression in Oral Inflammation and Regeneration2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Anti-HMGB1 neutralizing antibody attenuates periodontal inflammation and bone resorption in a murine periodontitis model.2018

Author(s)

Yamashiro Keisuke 山城圭介

YAMASHIRO KEISUKE 山城圭介

YAMASHIRO Keisuke 山城圭介

[Presentation] グリチルリチン酸経口投与によるin vivo 歯周組織治癒効果2014

[Presentation] グリチルリチン酸経口投与によるin vivo歯周組織治癒効果2014