OMORI KAZUHIRO 大森一弘

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OMORI Kazuhiro 大森一弘

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Researcher Number	20549860
Other IDs
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 岡山大学, 医歯薬学域, 准教授 2013 – 2021: 岡山大学, 大学病院, 講師 2012 – 2013: 岡山大学, 医歯(薬)学総合研究科, 助教 2009 – 2012: Okayama University, 大学院・医歯薬学総合研究科, 助教 2010: Okayama University, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Conservative dentistry / Periodontal dentistry / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Basic Section 57030:Conservative dentistry-related / Periodontology / Periodontal dentistry / Basic Section 59040:Nutrition science and health science-related / Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator 歯周病 / 根尖性歯周炎 / Porphyromonas gingivalis / 不妊 / terrein / 歯内疾患 / 糖尿病 / 免疫寛容 / 免役寛容 / 超高齢社会 … More / テレイン / TNF-alpha / 破骨細胞 / PKC / RANKL / TNF-alph / IL-6 / 有機合成化学 / 抗炎症 / 歯周疾患 / 低分子化合物 / 歯周・歯内疾患 / 歯周炎 / 細胞外基質 / ラミニン / IL-1α / 歯内療法 / シェディング / 慢性炎症 / 口腔感染管理 / 炎症 … More Except Principal Investigator 歯周病 / 歯周炎 / 炎症 / ジンジパイン / 病原因子 / 歯周病原細菌 / 細胞内カルシウム / 歯周病細菌 / 関節リウマチ / マクロファージ / 糖尿病 / 発育 / 細胞外分泌小胞 / 歯周病原菌 / VEGFR1 / 胎児 / 胎盤 / 細胞外小胞 / タンパク質分解酵素 / 炎症メディエーター / PLC / 血清抗体価 / シトルリン化蛋白 / lipid mediator / pulp capping / Dentin regeneration / Resolvin D2 (RVD2) / Dental pulp cells / Resolving D2 / Dental pulp cell / Reparative dentin / Resolvin D2 / Vital pulp therapy / 細胞応答 / 歯周組織の炎症 / Porphyromonas gingivalis / シクロオキシゲナーゼ-2 / プロスタグランジン / COX-2 / 細胞内シグナル伝達 / 炎症応答 / 歯周病菌 / follistatin / activin / 唾液腺 / サイトカイン遺伝子 / がん転移 / 慢性感染 / 癌転移 / 慢性炎症 / 歯周病悪化メカニズム / 糖尿病マウス / 歯肉線維芽細胞 / インターロイキン6レセプター / インターロイキン6 / 歯周病悪化 / MMP-3 Less

歯周病細菌主要病原因子ジンジパインの宿主直接作用と必須新奇オペロンの解明
- Principal Investigator
  
  大原直也
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Okayama University
The study of novel targets for infertility, with a focus on the link between oral disease (periodontal disease) and the uterus.Principal Investigator
- Principal Investigator
  
  大森一弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Okayama University
A Novel Mechanism of Infertility through the Oral-Uterine Interaction Induced by Periodontal Infection and InflammationPrincipal Investigator
- Principal Investigator
  
  大森一弘
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Molecular mechanisms of the inhibition of placenta and fetus development induced by periodontal disease
- Principal Investigator
  
  岡村裕彦
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Okayama University
Molecular mechanism of host cell response disruption and periodontal tissue destruction by proteases produced by periodontal bacteria
- Principal Investigator
  
  中山真彰
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Okayama University
APPLICATION OF RvD2 AS A REGENERATIVE DIRECT PULP CAPPING MATERIAL
- Principal Investigator
  
  ARIAS MARTINEZ Zulema Rosalia
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Pathogenesis of Rheumatoid Arthritis mediated by infection of periodontal pathogenic bacteria and citrullinated protein
- Principal Investigator
  
  Hatanaka Kazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
Identification and Functional Analysis of the Target Molecule of Terrein, a Small Molecule Compound for Application in the Super-Aging SocietyPrincipal Investigator
- Principal Investigator
  
  Omori Kazuhiro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
The mechanism of periodontal tissue destruction by proteases from periodontal bacteria Porpyromonas gingivalis.
- Principal Investigator
  
  Nakayama Masaaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Okayama University
Application of anti-inflammatory small molecule compound, terrein and its novel analogue, for the treatment of endodontic or periodontal diseases.Principal Investigator
- Principal Investigator
  
  Omori Kazuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
An analysis of shared risk cytokine gene for periodontitis, diabetes mellitus, and rheumatoid arthritis
- Principal Investigator
  
  YOSHIE Hiromasa
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University
唾液腺体性幹細胞とiPS細胞を用いた唾液腺機能再生に関する研究
- Principal Investigator
  
  峯柴淳二
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Okayama University
The development of novel endodontic treatment using IL-1alpha/laminin for periapical periodontitisPrincipal Investigator
- Principal Investigator
  
  Omori Kazuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
How periodontitis can affect prostate cancer metastasis?
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Possible Mechanisms of Progression of Periodontal Disease by TACE-Timp3 Interaction in Patients with Diabetes MellitusPrincipal Investigator
- Principal Investigator
  
  OMORI Kazuhiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
HMGB1ーRAGEシグナル系を標的とした糖尿病患者における炎症悪化機序の解明Principal Investigator
- Principal Investigator
  
  大森一弘
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Possible Mechanisms of Progression of Periodontits by MMP-3 in Diabetic Patients
- Principal Investigator
  
  NARUISHI Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Novel iron chelators, super-polyphenols, show antimicrobial effects against cariogenic Streptococcus mutans2023
- Author(s)
  Yuki Shinoda-Ito, Kazuhiro Omori, Takashi Ito, Masaaki Nakayama, Atsushi Ikeda, Masahiro Ito, Toshiaki Ohara, and Shogo Takashiba
- Journal Title
  
  Antibiotics (Basel)
  
  Volume: 12 Issue: 11 Pages: 1562-1574
- DOI
  10.3390/antibiotics12111562
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09842, KAKENHI-PROJECT-23K27773
[Journal Article] The Fungal Metabolite (+)-Terrein Abrogates Inflammatory Bone Resorption via the Suppression of TNF-α Production in a Ligature-Induced Periodontitis Mouse Model2023
- Author(s)
  Sako Hidefumi、Omori Kazuhiro、Nakayama Masaaki、Mandai Hiroki、Ideguchi Hidetaka、Yoshimura-Nakagawa Saki、Sakaida Kyosuke、Nagata-Kamei Chiaki、Kobayashi Hiroya、Ishii Satoki、Ono Mitsuaki、Ibaragi Soichiro、Yamamoto Tadashi、Suga Seiji、Takashiba Shogo
- Journal Title
  
  Journal of Fungi
  
  Volume: 9 Issue: 3 Pages: 314-314
- DOI
  10.3390/jof9030314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10108, KAKENHI-PROJECT-20K18509, KAKENHI-PROJECT-21K16992, KAKENHI-PROJECT-20K23054, KAKENHI-PROJECT-23K21486, KAKENHI-PROJECT-21K09842
[Journal Article] Porphyromonas gingivalis Gingipains Induce Cyclooxygenase-2 Expression and Prostaglandin E2 Production via ERK1/2-Activated AP-1 (c-Jun/c-Fos) and IKK/NF-κB p65 Cascades2022
- Author(s)
  Nakayama Masaaki、Naito Mariko、Omori Kazuhiro、Ono Shintaro、Nakayama Koji、Ohara Naoya
- Journal Title
  
  The Journal of Immunology
  
  Volume: 208 Issue: 5 Pages: 1146-1154
- DOI
  10.4049/jimmunol.2100866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10108, KAKENHI-PROJECT-20K18475, KAKENHI-PROJECT-21K09842, KAKENHI-PROJECT-20K09921
[Journal Article] The fungal metabolite (+)-terrein abrogates ovariectomy-induced bone loss and receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis by suppressing protein kinase-C α/βII phosphorylation.2021
- Author(s)
  Kyosuke Sakaida, Kazuhiro Omori, Masaaki Nakayama, Hiroki Mandai, Saki Nakagawa, Hidefumi Sako, Chiaki Kamei, Satoshi Yamamoto, Hiroya Kobayashi, Satoki Ishii, Mitsuaki Ono, Soichiro Ibaragi, Keisuke Yamashiro, Tadashi Yamamoto, Seiji Suga and Shogo Takashiba
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 674366-674366
- DOI
  10.3389/fphar.2021.674366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11668, KAKENHI-PROJECT-19K05456, KAKENHI-PROJECT-19K10108, KAKENHI-PROJECT-21K09842, KAKENHI-PROJECT-20K18509, KAKENHI-PROJECT-21K21087
[Journal Article] The Fungal Metabolite (+)-Terrein Abrogates Osteoclast Differentiation via Suppression of the RANKL Signaling Pathway through NFATc12020
- Author(s)
  S. Nakagawa, K. Omori, M. Nakayama, H. Mandai, S. Yamamoto, H. Kobayashi, H. Sako, K. Sakaida, H. Yoshimura, S. Ishii, S. Ibaragi, K. Hirai, K. Yamashiro, T. Yamamoto, S. Suga
- Journal Title
  
  Int. Immunopharmacol
  
  Volume: 83 Pages: 106429-106429
- DOI
  10.1016/j.intimp.2020.106429
- NAID
  120006892916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05478, KAKENHI-PUBLICLY-18H04415, KAKENHI-PROJECT-18K17069, KAKENHI-PROJECT-17K11668, KAKENHI-PROJECT-19K05456, KAKENHI-PROJECT-19K10108, KAKENHI-PROJECT-20K18509
[Journal Article] Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis.2019
- Author(s)
  Siddiqui YD, Omori K, Ito T, Yamashiro K, Nakamura S, Okamoto K, Ono M, Yamamoto T, Van Dyke TE, Takashiba S
- Journal Title
  
  Front Immunol
  
  Volume: 10 Pages: 307-307
- DOI
  10.3389/fimmu.2019.00307
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11549
[Journal Article] Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts2018
- Author(s)
  Satoshi Yamamoto, Kazuhiro Omori, Hiroki Mandai, Masaaki Nakayama, Saki Nakagawa, Hiroya Kobayashi, Tadashi Kunimine, Hiroshi Yoshimura, Kyosuke Sakaida, Hidefumi Sako, Soichiro Ibaragi, Tadashi Yamamoto, Hiroshi Maeda, Seiji Suga, and Shogo Takashiba
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 11 Pages: e00979-e00979
- DOI
  10.1016/j.heliyon.2018.e00979
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11668, KAKENHI-PROJECT-18K17069, KAKENHI-PROJECT-16K11549, KAKENHI-PROJECT-17K17903
[Journal Article] Naruishi K, Omori K, Maeda H, Sonoi N, Funakoshi K, Hirai K, Ishii M, Kubo K, Kobayashi H, Tomiyama T, Yamamoto D, Tanimoto I,Kunimatsu K, and Takashiba S2011
- Author(s)
  Naruishi K, Omori K, Maeda H, Sonoi N, Funakoshi K, Hirai K, Ishii M, Kubo K, Kobayashi H, Tomiyama T, Yamamoto D, Tanimoto I,Kunimatsu K, and Takashiba S
- Journal Title
  
  J Biol Regul Homeost Agents
  
  Volume: 25(2) Pages: 195-202
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] 岡山市医師会・疾患別検査と診断の手引き疾患別シリーズ(15)歯周病「歯周病と生活習慣病」2010
- Author(s)
  高柴正悟,大森一弘
- Journal Title
  
  岡山市医師会雑誌
  
  Pages: 115-122
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] 不妊病態の構築にPorphyromonas gingivalis感染を伴う歯周炎症が及ぼす影響の検討ー不妊治療中患者血清と絹糸結紮歯周炎マウスモデルを用いた解析ー2023
- Author(s)
  永田千晶，大森一弘，坂井田京佑，久保田萌可，大原利章，萬代大樹，平井公人，池田淳史，滝川雅之，山本直史，三宅貴仁，高柴正悟
- Organizer
  第67回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27773
[Presentation] 歯周組織の感染・炎症が惹起する子宮組織の肥厚と妊娠への影響．2022
- Author(s)
  永田千晶，大森一弘，井手口英隆，佐光秀文，坂井田京佑，久保田萌可，大原利章，萬代大樹，平井公人，池田淳史，山本直史，高柴正悟．
- Organizer
  日本歯科保存学会2022年度秋季学術大会（157回）
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] マウス絹糸結紮歯周炎モデルを用いた歯周感染が妊娠成績や子宮組織に及ぼす影響の検討．2022
- Author(s)
  永田千晶，大森一弘，井手口英隆，佐光秀文，坂井田京佑，大原利章，徳善真砂子，平井公人，山本直史，高柴正悟．
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] X連鎖性低リン血症性くる病を起因とした多発根尖病変に対し歯内療法を行なった症例2021
- Author(s)
  佐光秀文，大森一弘，坂井田京佑，亀井千晶，小林寛也，井手口英隆，山本直史，高柴正悟
- Organizer
  日本歯科保存学会2021年度春季学術大会（第154回）
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 歯周感染が子宮組織に及ぼす影響のマウス絹糸結紮歯周炎モデルにおける免疫学的検討2021
- Author(s)
  永田千晶，大森一弘，井手口英隆，佐光秀文，坂井田京佑，徳善真砂子，平井公人，山本直史，高柴正悟
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] Resolvin D2 Promotes the Formation of Calcified Tissue on Pulp2021
- Author(s)
  Mitsuhiro Yoneda, Zulema Rosalia Arias Martinez, Shin Nakamura, Kentaro Okamoto, Masahiro Ito, Kazuya Tamura, Hidetaka Ideguchi, Kazuhiro Omori, Keisuke Yamashiro, Tadashi Yamamoto, Shogo Takashiba.
- Organizer
  2021 IADR/ AADR/ CADR General Session
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09938
[Presentation] Infertility and Periodontitis2021
- Author(s)
  Omori Kauzhiro
- Organizer
  69th JADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 真菌代謝産物(+)-terreinがマウス骨粗鬆症モデルにおける骨代謝に及ぼす影響2020
- Author(s)
  坂井田京佑, 大森一弘, 中川沙紀, 佐光秀文, 亀井千晶, 山本総司, 小林寛也, 山城圭介, 山本直史, 高柴正悟
- Organizer
  日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 真菌二次代謝産物(+)-terreinはTNF-αの発現を抑制し歯周炎マウスモデルにおける歯槽骨吸収を抑制する2020
- Author(s)
  佐光秀文, 大森一弘, 中川沙紀, 亀井千晶, 坂井田京佑, 山本総司, 井手口英隆, 小林寛也, 山城圭介, 山本直史, 高柴正悟
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 歯周組織再生療法の違いが歯肉縁下細菌叢に及ぼす影響　侵襲性歯周炎患者の一症例2020
- Author(s)
  大森一弘, 河野隆幸, 新井英雄, 小林寛也, 山本直史, 高柴正悟
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 真菌二次代謝産物terreinはマウス歯周病モデルにおける歯槽骨吸収を抑制する2019
- Author(s)
  佐光秀文, 大森一弘, 中川沙紀, 坂井田京佑, 山本総司, 青柳浩明, 小林寛也, 大野充昭, 平井公人, 山城圭介, 山本直史, 高柴正悟
- Organizer
  第39回日本歯科薬物療法学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] Terrein類縁体の抗腫瘍効果に関する研究2019
- Author(s)
  廣瀬泰良, 伊原木聰一郎, 大森一弘, 中山真彰, 佐々木朗
- Organizer
  岡山歯学会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 真菌二次代謝産物terreinはマウス骨粗鬆症モデルにおいて大腿骨吸収を抑制する2019
- Author(s)
  坂井田京佑, 大森一弘, 中川沙紀, 佐光秀文, 山本総司, 小林寛也, 平井公人, 山城圭介, 山本直史, 高柴正悟
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-19K10108
[Presentation] 真菌二次代謝産物(+)-terreinはマウス実験的歯周炎モデルにおける歯槽骨吸収を抑制する2018
- Author(s)
  佐光秀文, 大森一弘, 中川沙紀, 坂井田京佑, 山本総司, 青柳浩明, 小林寛也, 山城圭介, 山本直史, 高柴正悟
- Organizer
  第149回日本歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] 真菌二次代謝産物(+)-terreinはヒト歯肉上皮細胞におけるAggregatibacter actinomycetemcomitans刺激による細胞間接着分子の発現低下を抑制する2018
- Author(s)
  中村亜里紗, 大森一弘, 小林寛也, 冨川知子, 山本総司, 中川沙紀, 山本直史, 高柴正悟
- Organizer
  第148回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] 真菌代謝産物terreinはAggregatibacter actinomycetemcomitans歯肉上皮感染時のIL-8産生を抑制する2017
- Author(s)
  中村亜里紗, 大森一弘, 小林寛也, 山本総司, 中川沙紀, 冨川知子, 峯柴史, 山本直史, 高柴正悟
- Organizer
  第60回日本歯周病学会春季学術大会
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] Fungal metabolite, terrein, suppresses IL-6/sIL-6R-induced CSF1 secretion in gingival fibroblasts2017
- Author(s)
  S. Yamamoto, K Omori, A. Goto, H. Kobayashi, S. Nakagawa, A. Nakamura, D. Yamamoto, T. Yamamoto, S. Takashiba
- Organizer
  95th, International Association for Dental Research
- Place of Presentation
  San Francisco, CA, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] 真菌二次代謝産物(+)-terreinはRANKL誘導性破骨細胞分化におけるNFATc1の発現を抑制する2017
- Author(s)
  中川沙紀, 大森一弘, 山本総司, 小林寛也, 河村麻理, 中村亜里紗, 山本直史, 高柴正悟
- Organizer
  日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] 真菌由来代謝産物(+)-terreinはヒト歯肉線維芽細胞におけるinterleukin-6誘導性SHP2-AKTシグナル活性を抑制する2016
- Author(s)
  山本総司，大森一弘，後藤絢香，小林寛也，中川沙紀，中村亜里紗，冨川知子，山本直史，髙柴正悟
- Organizer
  第58回日本歯周病学会春季学術大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K11549
[Presentation] 真菌由来代謝産物(+)-terrein誘導体がIL-6誘導性VEGFおよびCSF-1の産生に及ぼす影響の検討2015
- Author(s)
  山本総司，大森一弘，後藤絢香，池田淳史，小林寛也，中川沙紀，山本大介，山本直史，前田博史，髙柴正悟
- Organizer
  第58回日本歯周病学会春季学術大会
- Place of Presentation
  千葉
- Year and Date
  2015-05-18
- Data Source
  KAKENHI-PROJECT-25861801
[Presentation] 真菌由来代謝産物(+)-terreinはRANKL誘導性破骨細胞分化を抑制する2015
- Author(s)
  中川沙紀，大森一弘，山本総司，小林寛也，後藤絢香，中村亜里紗，山本直史，髙柴正悟
- Organizer
  第143回日本歯科保存学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25861801
[Presentation] IL-6/sIL-6R enhances cathepsin-B secretion via caveolin-1-mediated ERK1/2 in gingival fibroblasts.2015
- Author(s)
  Goto A, Omori K, Yamaguchi-Tomikawa, Kobayashi H, Yamamoto T, Maeda H, Takashiba S
- Organizer
  the 93rd International Association for Dental Research
- Place of Presentation
  Boston, USA
- Year and Date
  2015-03-14
- Data Source
  KAKENHI-PROJECT-25253104
[Presentation] 新たな糖尿病合併症に迫る　～糖尿病患者にとっての歯周病治療を再考する～2015
- Author(s)
  大森一弘，髙柴正悟
- Organizer
  第29回日本糖尿病合併症学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2015-11-25
- Data Source
  KAKENHI-PROJECT-25861801
[Presentation] I-6s/IL-6Rは歯肉線維芽細胞から活性を有するリソソーム酵素カテプシンB, Lの分泌を亢進す2014
- Author(s)
  後藤絢香，大森一弘，冨川知子，小林寛也，成石浩司，前田博史，高柴正悟
- Organizer
  第57回秋季日本歯周病学会学術大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-25253104
[Presentation] 真菌由来代謝産物(+)-terreinはinterleukin-6誘導生colony stimulating factor-1の遺伝子発現を抑制する2014
- Author(s)
  山本総司，大森一弘，後藤絢香，池田淳史，松永一幸，山本大介，山本直史，前田博史，髙柴正悟
- Organizer
  第135回日本歯科保存学会秋季学術大会
- Place of Presentation
  山形
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-25861801
[Presentation] IL-6/sIL-6Rは歯肉線維芽細胞から活性を有するリソソーム酵素カテプシンB，Lの分泌を亢進する2014
- Author(s)
  後藤絢香，大森一弘，冨川知子，小林寛也，成石浩司，前田博史，髙柴正悟
- Organizer
  第57回日本歯周病学会秋季学術大会
- Place of Presentation
  神戸
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25861801
[Presentation] 血管新生阻害物質terrein がヒト歯肉線維芽細胞におけるIL-6/sIL-6R誘導性angiogeninおよびVEGFの産生に及ぼす影響2013
- Author(s)
  1. 山本大介，大森一弘，小林寛也，冨山高史，久保克行，成石浩司，前田博史，高柴正
- Organizer
  第56回日本歯周病学会春季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25861801
[Presentation] Activated MMP-3 enhances sIL-6R production in macrophage like differentiated THP-1 cells2012
- Author(s)
  Hiroya Kobayashi, Kazuhiro Omori, Koji Naruishi, Tomoko Yamaguchi, Hiroshi Maeda, Shogo Takashiba
- Organizer
  90thInternational Association for Dental Research
- Place of Presentation
  Iguacu falls, Brazil
- Year and Date
  2012-06-22
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] Activated MMP-3 enhances sIL-6R production in macrophage like differentiated THP-1 cells2012
- Author(s)
  H. Kobayashi, K. Omori et al
- Organizer
  90th International Association for Dental Research
- Place of Presentation
  Iguacu falls, Brazil
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] 活性型 MMP-3 がマクロファージ様 THP-1 細胞の膜型 IL-6 受容体の発現に及ぼす影響2011
- Author(s)
  小林寛也,大森一弘,成石浩司,山口知子,冨山高史,久保克行,山本大介,前田博史,高柴正悟
- Organizer
  第133回日本歯科保存学会春季学術大会
- Place of Presentation
  東京
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] Activated MMP-3 enhances sIL-6R production in macrophage like differentiated THP-1 cells2011
- Author(s)
  Hiroya Kobayashi, Kazuhiro Omori, Koji Naruishi, Tomoko Yamaguchi, Hiroshi Maeda, Shogo Takashiba
- Organizer
  59thJapanese Association for Dental Research
- Place of Presentation
  Hiroshima, Japan
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] 活性型MMP-3がマクロファージ様THP-1細胞の膜型IL-6受容体の発現に及ぼす影響2011
- Author(s)
  小林寛也, 大森一弘, ら
- Organizer
  第134回日本歯科保存学会春季学術大会
- Place of Presentation
  東京ベイ舞浜ホテルクラブリゾート(千葉)
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] Activated MMP-3 enhances sIL-6R production in macrophage like differentiated THP-1 cells2011
- Author(s)
  H.Kobayashi, K.Omori, et al
- Organizer
  59th Japanese Association for Dental Research
- Place of Presentation
  広島国際会議場(広島)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] MMP-3 によるヒト単球系細胞株THP-1 からの可溶型 IL-6 受容体の産生亢進2010
- Author(s)
  小林寛也,大森一弘,成石浩司,冨山高史,久保克行,山口知子,前田博史,高柴正悟
- Organizer
  第132回日本歯科保存学会春季学術大会
- Place of Presentation
  熊本
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] Inhibition of IL-6/sIL-6R-induced VEGF production by sgp130 in gingival fibroblasts.2010
- Author(s)
  山口知子, 成石浩司, 大森一弘, 前田博史, 高柴正悟
- Organizer
  88th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] IL-1raによるマウス骨芽細胞様細胞MC3T3-E1におけるIl-1誘導性OPGおよびIL-6産生制御2010
- Author(s)
  久保克行, 大森一弘, ら
- Organizer
  第53回日本歯周病学会春季学術大会
- Place of Presentation
  盛岡市民文化ホール(岩手)
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] IL-1raによるマウス骨芽細胞様細胞MC3T3-E1におけるIL-1誘導性OPGおよびIL-6の産生制御2010
- Author(s)
  久保克行, 大森一弘, 成石浩司, 冨山高史, 小林寛也, 山口知子, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] MMP-3によるヒト単球系細胞株THP-1からの可溶型IL-6受容体の産生亢進2010
- Author(s)
  小林寛也, 大森一弘, ら
- Organizer
  第132回日本歯科保存学会春季学術大会
- Place of Presentation
  崇城大学市民ホール(熊本)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-22792083
[Presentation] nrdD様遺伝子の存在は血中移行したPorphyromonas gingivalisの病原性を決定する2010
- Author(s)
  園井教裕, 前田博史, 成石浩司, 苔口進, 大森一弘, 石井真由美, 平井公人, 山部こころ, 谷本一郎, 高柴正悟
- Organizer
  第53回日本歯周病学会秋期学術大会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] MMP-3によるヒト単球系細胞株THP-1からの可溶型IL-6受容体の産生亢進2010
- Author(s)
  小林寛也, 大森一弘, 成石浩司, 山口知子, 冨山高史, 久保克行, 前田博史, 高柴正悟
- Organizer
  第132回日本歯科保存学会春期学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯周病原細菌の感染による全身性炎症性反応に抗する免疫応答の意義2010
- Author(s)
  成石浩司, 園井教裕, 大森一弘, 前田博史, 高柴正悟, 國松和司
- Organizer
  第133回日本歯科保存学会秋期学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯周病治療を通じて, II型糖尿病患者の行動変容を促した一症例2009
- Author(s)
  大森一弘, ら
- Organizer
  第24回日本糖尿病合併症学会
- Place of Presentation
  岡山コンベンションセンター(岡山県)
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21890150
[Presentation] 糖尿病教室における歯科の役割-歯周病が全身疾患(糖尿病)に及ぼす影響について-2009
- Author(s)
  大森一弘
- Organizer
  第14回岡山県糖尿病療養指導フォーラム
- Place of Presentation
  岡山国際交流会館(岡山県)
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-21890150
[Presentation] 歯肉線維芽細胞を標的としたカベオリン-1および可溶性gp130によるIL-6誘導性VEGF産生の抑制制御2009
- Author(s)
  山口知子, 成石浩司, 大森一弘, 新井英雄, 高柴正悟
- Organizer
  第130回日本歯科保存学会春期学術大会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20592428

1. TAKASHIBA Syougo (50226768)

# of Collaborated Projects: 8 results

# of Collaborated Products: 26 results
2. Nakayama Masaaki (10579105)

# of Collaborated Projects: 7 results

# of Collaborated Products: 6 results
3. 萬代大樹 (60534427)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
4. MINESHIBA Junji (00509383)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 大原直也 (70223930)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. NARUISHI Koji (00346446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. HATANAKA Kazu (50362992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 大原利章 (40623533)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. TANIMOTO Ichiro (00280686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. WATANABE Masami (70444677)

# of Collaborated Projects: 1 results

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11. YOSHIE Hiromasa (20143787)

# of Collaborated Projects: 1 results

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12. ARIAS MARTINEZ Zulema Rosalia (70824580)

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# of Collaborated Products: 1 results
13. 塩見信行 (90432632)

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14. 永田俊彦 (10127847)

# of Collaborated Projects: 1 results

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15. 三谷章雄 (50329611)

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16. 石原裕一 (50261011)

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17. 小林哲夫 (00215344)

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# of Collaborated Products: 2 results
18. 木戸淳一 (10195315)

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19. 前田博史 (00274001)

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# of Collaborated Products: 2 results
20. 野口俊英 (50014262)

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21. 山本直史 (50432662)

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22. 後藤和義 (20626593)

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23. 竹内恒 (20581284)

# of Collaborated Projects: 1 results

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24. 山城圭介 (30581087)

# of Collaborated Projects: 1 results

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25. 佐藤啓子 (70410579)

# of Collaborated Projects: 1 results

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26. 大原直子 (80301365)

# of Collaborated Projects: 1 results

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27. 武部克希 (61000104)

# of Collaborated Projects: 1 results

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28. 岡村裕彦 (20380024)

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29. 十川千春 (10253022)

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30. 江口傑徳 (20457229)

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31. 池亀美華 (70282986)

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32. 福原瑶子 (60779742)

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33. 菅誠治

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OMORI KAZUHIRO 大森 一弘

OMORI Kazuhiro 大森 一弘

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The study of novel targets for infertility, with a focus on the link between oral disease (periodontal disease) and the uterus.Principal Investigator

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A Novel Mechanism of Infertility through the Oral-Uterine Interaction Induced by Periodontal Infection and InflammationPrincipal Investigator

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Identification and Functional Analysis of the Target Molecule of Terrein, a Small Molecule Compound for Application in the Super-Aging SocietyPrincipal Investigator

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Application of anti-inflammatory small molecule compound, terrein and its novel analogue, for the treatment of endodontic or periodontal diseases.Principal Investigator

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The development of novel endodontic treatment using IL-1alpha/laminin for periapical periodontitisPrincipal Investigator

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OMORI KAZUHIRO 大森一弘

OMORI Kazuhiro 大森一弘