Naruishi Koji 成石浩司

… Alternative Names

Researcher Number	00346446
Other IDs
Affiliation (Current)	2022: 徳島大学, 病院, 講師
Affiliation (based on the past Project Information) *help	2022: 徳島大学, 大学病院, 講師 2016 – 2020: 徳島大学, 病院, 講師 2015: 徳島大学, 大学病院, 講師 2012: 岩手医科大学, 歯学部, 歯学部 2010 – 2012: 岩手医科大学, 歯学部, 准教授 … More
Review Section/Research Field	Principal Investigator Periodontal dentistry / Basic Section 57030:Conservative dentistry-related / Periodontology Except Principal Investigator Periodontology / Periodontal dentistry / Conservative dentistry / Respiratory organ internal medicine / Periodontal dentistry
Keywords	Principal Investigator 歯肉線維芽細胞 / 糖尿病 / マクロファージ / 歯周病悪化メカニズム / MMP-3 / インターロイキン6 / 糖尿病性歯周炎 / 遺伝子マイクロアレイ解析 / 歯周病悪化 / インターロイキン6レセプター … More Except Principal Investigator 歯周病 / MAPK / 遺伝子導入 / 慢性感染 / 糖尿病関連歯周炎 / 歯肉線維芽細胞 / 慢性歯周炎 / 歯周病原細菌に対する血漿IgG抗体価 / 指尖採血 / 歯周病診断 / マルチセンター式研究 / 歯周病菌に対するIgG抗体価 / 保存修復学 / 口腔感染症 / 口腔ケア / バイオフィルム / 感染症 / 根尖性歯周炎 / 骨芽細胞 / IL-1 / ラミニン / 病巣治癒 / インターロイキン1α / 根尖病巣 / 冶癒 / インターロイキン1a / 細胞増殖活性 / 細胞接着活性 / 歯根膜 / 細胞分化 / RhoA-ROCKシグナル / Y-27632 / 遺伝子発現 / RhoA / ROCK / Rho / Rho-kinase / ストレスファイバー / COPD増悪 / 宿主免疫 / 感染 / 慢性閉塞性肺疾患 / 気道炎症 / 歯周炎 / 慢性炎症 / 癌転移 / がん転移 / 末梢血幹細胞移植 / 易感染性宿主 / 口腔管理 / 歯周疾患 / 細菌検査 / 白血球数 / PBSCT / compromised host / oral infection control / periodontal desease / bacterial detection / leukocyte / 象牙質・歯髄複合体 / ラット創傷歯髄 / TNF-αシグナル / プロモーター活性 / 転写因子結合部位 / 細胞死 / TNF-αパスウェイ / dentin-pulp complex / rat wounded pulp / TNF-α signaling / promoter activity / transcription factor-binding site / over-expression / cell death / 最終糖化産物 / 炎症関連因子 / 炎症性サイトカイン / 酸化ストレス / インフラマソーム / インプラント疾患 / インプラント周囲溝液 / バイオマーカー / 診断デバイス / インプラント粘膜炎・周囲炎 / 疾患診断 / AGE / マクロファージ / 糖尿病性関連歯周炎 / 糖尿病 / 人工細胞 / リポソーム / 抗菌ペプチド / 無細胞蛋白合成 / オーラルケア / 無細胞蛋白質合成 Less

老齢性テストステロン低下とＡＧＥ上昇に着目した糖尿病関連歯周炎の治療戦略Principal Investigator
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
Pathophysiology of periodontitis progression by IL-1 and geriatric impaired testosterone in diabetic patientsPrincipal Investigator
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  The University of Tokushima
人工細胞を用いたオーラルケアシステムの基礎研究
- Principal Investigator
  
  木戸淳一
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
Crosstalk of Gingival Fibroblasts and Macrophages in Inflammatory Cytokine Cascade: Potential Mechanisms of Periodontitis with Diabetes.Principal Investigator
- Principal Investigator
  
  NARUISHI Koji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
Effect of advanced glycation end-products and inflammasome for pathogenesis of Diabetes mellitus-associated periodontitis
- Principal Investigator
  
  BANDO Mika
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
Diagnosis of peri-implant diseases by cellular biomarkers and development of diagnostic device
- Principal Investigator
  
  KIDO Jun-ichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
Pathophysiology of diebetes-associated periodontitis and establishment of novel diagnosis system of diabetes-associated periodontitis
- Principal Investigator
  
  NAGATA Toshihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  The University of Tokushima
ＡＰ－１によるカテプシン産生制御に着目した歯肉増殖症・歯周病診断の新機軸Principal Investigator
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Iwate Medical University
How periodontitis can affect prostate cancer metastasis?
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Chronic infection and immune response in COPD patients
- Principal Investigator
  
  MURO Shigeo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto University
Healing mechanism of rat experimental periapical lesions targeting laminin γ2 expression
- Principal Investigator
  
  HATANAKA Kazu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Possible Mechanisms of Progression of Periodontits by MMP-3 in Diabetic PatientsPrincipal Investigator
- Principal Investigator
  
  NARUISHI Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Investigation of the mechanisms of osteogenic differentiation by RhoA in periodontal ligament cells for cell transplantation
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
New bactericide delivery system for oral care
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Mail Medicine using Fingertip Plasma for Screening and Monitoring Periodontitis
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
糖尿病患者の歯周病悪化を誘発する新規因子の網羅的な解析および同定Principal Investigator
- Principal Investigator
  
  成石浩司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
The effect on dentin-pulp complex by FIP-2 isolated from rat wounded pulp
- Principal Investigator
  
  ARAI Hideo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Study for oral infectious control during peripheral blood stem cell transplantation
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University

All 2020 2019 2018 2017 2016 2015 2013 2011 2010 2009 2008 2006 Other

All Journal Article Presentation

[Journal Article] Inhibitory Effects of Sudachitin on the Production of Inflammation-related Molecules in Human Gingival Fibroblasts Cultured under High Glucose Conditions2020
- Author(s)
  西川泰史, 成石浩司, 木戸淳一, 湯本浩通
- Journal Title
  
  Jpn J Conserv Dent
  
  Volume: 63 Issue: 6 Pages: 503-511
- DOI
  10.11471/shikahozon.63.503
- NAID
  130007964638
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10131
[Journal Article] Carotenoids and Periodontitis2020
- Author(s)
  Koji Naruishi
- Journal Title
  
  Nutrients
  
  Volume: 12
- DOI
  10.3390/nu12010269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10131
[Journal Article] 講義および実習試験の評価による歯周病学教育のあり方の考察2020
- Author(s)
  成石浩司，坂本英次郎，生田貴久，木戸理恵，木戸淳一，湯本浩通
- Journal Title
  
  日本歯科保存学雑誌
  
  Volume: 63 Pages: 22-29
- NAID
  130007804952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10131
[Journal Article] Disequilibrium of Plasma Protease/Anti-Protease Due to Severe Periodontal Disease Contributes to Human Subarachnoid Hemorrhage2020
- Author(s)
  Yoshioka S, Miyamoto T, Satomi J, Tada Y, Yagi K, Shimada K, Naruishi K, Shikata E, Yamaguchi I, Yamaguchi1 T, Korai M, Okayama Y, Harada M, Kitazato K, Kanematsu Y, Nagahiro S, Takagi Y
- Journal Title
  
  Neurosurgery Open
  
  Volume: 1 Pages: 1-9
- DOI
  10.1093/neuopn/okaa007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10131, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-19K24013
[Journal Article] 6-Shogaol inhibits advanced glycation end-products-induced IL-6 and ICAM-1 expression by regulating oxidative responses in human gingival fibroblasts2019
- Author(s)
  Kohei Nonaka, Mika Bando, Eijiro Sakamoto, Yuji Inagaki, Koji Naruishi, Hiromichi Yumoto, Jun-ichi Kido
- Journal Title
  
  Molecules
  
  Volume: 24
- DOI
  10.3390/molecules24203705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04418
[Journal Article] Clinical effects of low body mass index on geriatric status in elderly patients.2018
- Author(s)
  Naruishi K, Yumoto H, Kido JI
- Journal Title
  
  Exp Gerontol
  
  Volume: 110 Pages: 86-91
- DOI
  10.1016/j.exger.2018.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11832
[Journal Article] β-carotene suppresses Porphyromonas gingivalis lipopolysaccharide-mediated cytokine production in THP-1 monocytes cultured with high glucose condition.2018
- Author(s)
  Kajiura Y, Nishikawa Y, Lew JH, Kido JI, Nagata T, Naruishi K.
- Journal Title
  
  Cell Biol Int
  
  Volume: 42(1) Pages: 105-111
- DOI
  10.1002/cbin.10873
- NAID
  120006539758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05054, KAKENHI-PROJECT-16K11832
[Journal Article] Advanced glycation end-products increase IL-6 and ICAM-1 expression via RAGE, MAPK and NF-κB pathways in human gingival fibroblasts2018
- Author(s)
  Nonaka K.、Kajiura Y.、Bando M.、Sakamoto E.、Inagaki Y.、Lew J. H.、Naruishi K.、Ikuta T.、Yoshida K.、Kobayashi T.、Yoshie H.、Nagata T.、Kido J.
- Journal Title
  
  J Periodontal Res.
  
  Volume: - Pages: 1-11
- DOI
  10.1111/jre.12518
- NAID
  120006845647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11391, KAKENHI-PROJECT-15K20621
[Journal Article] Biological effects of interleukin-6 on Gingival Fibroblasts: Cytokine regulation in periodontitis.2018
- Author(s)
  Naruishi K, Nagata T
- Journal Title
  
  J Cell Physiol
  
  Volume: 印刷中 Pages: 6393-6400
- DOI
  10.1002/jcp.26521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05054, KAKENHI-PROJECT-16K11832
[Journal Article] Relationship of aspiration pneumonia to cognitive impairment and oral condition: a cross-sectional study.2018
- Author(s)
  Naruishi K, Nishikawa Y, Kido JI, Fukunaga A, Nagata T.
- Journal Title
  
  Clin Oral Investig
  
  Volume: 印刷中
- DOI
  10.1007/s00784-018-2356-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05054
[Journal Article] Local administration of calcitonin inhibits alveolar bone loss in an experimental periodontitis in rats.2018
- Author(s)
  Wada-Mihara C, Seto H, Ohba H, Tokunaga K, Kido JI, Nagata T, Naruishi K.
- Journal Title
  
  Biomed Pharmacother
  
  Volume: 97 Pages: 765-770
- DOI
  10.1016/j.biopha.2017.10.165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05054
[Journal Article] High Glucose-Mediated Cytokine Regulation in Gingival Fibroblasts and THP-1 Macrophage: a Possible Mechanism of Severe Periodontitis with Diabetes.2018
- Author(s)
  Lew JH, Naruishi K, Kajiura Y, Nishikawa Y, Ikuta T, Kido JI, Nagata T.
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 50(3) Pages: 973-986
- DOI
  10.1159/000494481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11832
[Journal Article] Crosstalk of Gingival Fibroblasts and Macrophages in Inflammatory Cytokine Cascade: Potential Mechanisms of Periodontitis2017
- Author(s)
  Naruishi K, Nishikawa Y
- Journal Title
  
  J Cell Signaling
  
  Volume: 2 (2)
- DOI
  10.4172/2576-1471.1000149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11832
[Journal Article] Clinical significance of GCF sIL-6R and calprotectin to evaluate the periodontal inflammation2017
- Author(s)
  Kajiura Y, Lew JH, Ikuta T, Nishikawa Y, Kido J, Nagata T, Naruishi K. ANNALS EXPRESS
- Journal Title
  
  Ann Clin Biochem.
  
  Volume: 印刷中 Pages: 664-670
- DOI
  10.1177/0004563216680232
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25253104, KAKENHI-PROJECT-16K20673, KAKENHI-PROJECT-15H05054, KAKENHI-PROJECT-15K20621
[Journal Article] Calprotectin induces IL-6 and MCP-1 production via Toll-like receptor 4 signaling in human gingival fibroblasts2017
- Author(s)
  Nishikawa Y, Kajiura Y, Lew JH, Kido J, Nagata T, Naruishi K.
- Journal Title
  
  J Cell Physiol
  
  Volume: 印刷中 Pages: 1862-1871
- DOI
  10.1002/jcp.25724
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253104, KAKENHI-PROJECT-15K15701, KAKENHI-PROJECT-16K11832, KAKENHI-PROJECT-15H05054
[Journal Article] Calprotectin Induces IL-6 and MCP-1 Production via Toll-Like Receptor 4 Signaling in Human Gingival Fibroblasts.2017
- Author(s)
  2.Nishikawa Y, Kajiura Y, Lew JH, Kido JI, Nagata T, Naruishi K.
- Journal Title
  
  J Cell Physiol
  
  Volume: 232 Pages: 1862-1871
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Journal Article] Clinical Significance of GCF sIL-6R and Calprotectin to Evaluate the Periodontal Inflammation2017
- Author(s)
  Kajiura Y, Lew JH, Ikuta T, Nishikawa Y, Kido JI, Nagata T, Naruishi K
- Journal Title
  
  Ann Clin Biochem
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11832
[Journal Article] Association between periodontal condition and kidney dysfunction in japanese aduls: A cross-sectional study2016
- Author(s)
  1.Naruishi K, Oishi K, Inagaki Y, Horibe M, Bando M, Ninomiya M, Kawahara K, Minakuchi J, Kawashima S, Shima K, Kido J, Nagata T.
- Journal Title
  
  Clinical and Experimental Dental Research
  
  Volume: 2 Pages: 1-8
- DOI
  10.1002/cre2.39
- NAID
  120006937621
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054, KAKENHI-PROJECT-26463135
[Journal Article] 肥満糖尿病ラット歯周炎の歯肉組織におけるオステオポンチンの局在2015
- Author(s)
  稲垣裕司、中島由紀子、堀部ますみ、生田貴久、梶浦由加里、成石浩司、木戸淳一、永田俊彦
- Journal Title
  
  日本歯周病学会会誌
  
  Volume: 57 Pages: 149-158
- NAID
  130005116213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05054
[Journal Article] YKL-40 level in gingival crevicular fluid from patients with periodontitis and type 2 diabetes2015
- Author(s)
  Kido J, Bando Y, Bando M, Kajiura Y, Hiroshima Y, Inagaki Y, Murata H, Ikuta T, Kido R, Naruishi K, Funaki M, Nagata T.
- Journal Title
  
  Oral Diseases
  
  Volume: 21 Pages: 667-673
- DOI
  10.1111/odi.12334
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253104, KAKENHI-PROJECT-15H05054
[Journal Article] Secreted caveolin-1 enhances periodontal inflammation by targeting gingival fibroblasts2013
- Author(s)
  Takizawa N, Sawada S, Chosa N, Ishisaki A, Naruishi K
- Journal Title
  
  Biomed Res
  
  Volume: 34(1) Pages: 1-11
- NAID
  130004470829
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] 医科歯科連携医療における歯周病原細菌に対する血清IgG抗体価検査の導入2011
- Author(s)
  村井治, 成石浩司, 佐々木大輔, 大川義人, 八重柏隆, 國松和司
- Journal Title
  
  日本口腔検査学会雑誌第3巻1号
  
  Pages: 36-41
- Data Source
  KAKENHI-PROJECT-20592428
[Journal Article] Naruishi K, Omori K, Maeda H, Sonoi N, Funakoshi K, Hirai K, Ishii M, Kubo K, Kobayashi H, Tomiyama T, Yamamoto D, Tanimoto I,Kunimatsu K, and Takashiba S2011
- Author(s)
  Naruishi K, Omori K, Maeda H, Sonoi N, Funakoshi K, Hirai K, Ishii M, Kubo K, Kobayashi H, Tomiyama T, Yamamoto D, Tanimoto I,Kunimatsu K, and Takashiba S
- Journal Title
  
  J Biol Regul Homeost Agents
  
  Volume: 25(2) Pages: 195-202
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] Cathepsin B, D, and L Regulation in Cyclosporin A-mediated Gingival Hyperplasia of a Patient with Sarcoidosis.2011
- Author(s)
  Osamu Murai, Koji Naruishi, Satoshi Ogihara, Nagisa Suwa, Satomi Kanazawa, Takashi Yaegashi, Yasunori Takeda, Kazushi Kunimatsu
- Journal Title
  
  Clin.Lab. in Press
- Data Source
  KAKENHI-PROJECT-20592428
[Journal Article] Immune responses to porphyromonas gingivalis infection suppress systemic inflammatory response in experimental murine model2011
- Author(s)
  Naruishi, Koji
- Journal Title
  
  Journal of biological regulators and homeostatic agents
  
  Volume: 25 Pages: 195-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592312
[Journal Article] IL-6/sIL-6R enhances cathepsin B and L production via caveolin-1-mediated JNK-AP-1 pathway in human gingival fibroblasts.2008
- Author(s)
  Yamaguchi T, Naruishi K, Arai H, Nishimura F, Takashiba s.
- Journal Title
  
  Journal of Cellular Physiology 217
  
  Pages: 423-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592428
[Journal Article] 高血糖状態で培養したヒト歯肉線維芽細胞の網羅的な遺伝子解析2006
- Author(s)
  成石浩司ら
- Journal Title
  
  第20回日本顎頭蓋機能学会記念学術大会抄録集 20巻・1号
  
  Pages: 19-19
- NAID
  10018119680
- Data Source
  KAKENHI-PROJECT-18791592
[Journal Article] Porphyromonas gingivalis fimbriae-dependent interleukin-6 autocrine regulation by increase of gp130 in endothelial cells
- Author(s)
  Y-S. Ho, M-T. Lai, S-J. Liu, C-T. Lin, K. Naruishi, S. Takashiba, H-H. Chou
- Journal Title
  
  Journal of Periodontal Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] PCRを用いたPorphyromonas gingivalis迅速検出システムの有用性2020
- Author(s)
  秋月皆人，二宮雅美，植村勇太，生田貴久，成石浩司，湯本浩通
- Organizer
  第153回日本歯科保存学会秋期学術大会
- Data Source
  KAKENHI-PROJECT-19K10131
[Presentation] 無細胞蛋白質合成系を用いた抗菌ペプチドの合成とリポソーム封入2020
- Author(s)
  木戸淳一，廣島佑香，木戸理恵，稲垣裕司，成石浩司，湯本浩通
- Organizer
  第152回日本歯科保存学会春期学術大会
- Data Source
  KAKENHI-PROJECT-19K10131
[Presentation] 最終糖化産物はヒト口腔上皮細胞のリポカリン2発現を増加する2019
- Author(s)
  木戸理恵，廣島佑香，生田貴久，吉田賀弥，稲垣裕司，成石浩司，尾崎和美，木戸淳一，湯本浩通
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04418
[Presentation] Diabetic High-Glucose Condition Enhances Calprotectin-induced Inflammatory Responses in Gingival Fibroblasts.2019
- Author(s)
  Nishikawa Y, Naruishi K, Yumoto H.
- Organizer
  97th International Association for Dental Research, General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10131
[Presentation] ショウガオールはヒト歯肉線維芽細胞においてAGEs誘導性の酸化ストレスを抑制する2019
- Author(s)
  野中康平，板東美香，木戸淳一，稲垣裕司，坂本英次郎，成石浩司，湯本浩通
- Organizer
  第62回日本歯周病学会秋期学術大会
- Data Source
  KAKENHI-PROJECT-19K10131
[Presentation] Diabetic High-Glucose Condition Enhances Calprotectin-induced Inflammatory Responses in Gingival Fibroblasts.2019
- Author(s)
  Nishikawa Y, Naruishi K, Yumoto H.
- Organizer
  97th International Association for Dental Research, General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] オーラルケアへの応用を目指した抗菌ペプチド合成とリポソーム封入2019
- Author(s)
  廣島佑香，木戸淳一，木戸理恵，吉田賀弥，稲垣裕司，成石浩司，湯本浩通
- Organizer
  第62回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04418
[Presentation] 重度慢性歯周炎を有する血液透析患者に対して包括的歯周治療を行った一症例2019
- Author(s)
  二宮雅美，生田貴久，成石浩司，湯本浩通
- Organizer
  第151回日本歯科保存学会秋期学術大会
- Data Source
  KAKENHI-PROJECT-19K10131
[Presentation] インプラント周囲溝滲出液中のカルプロテクチンとNTxを用いたインプラント疾患の診断2018
- Author(s)
  木戸理恵，坂本英次郎，板東美香，稲垣裕司，二宮雅美，美原智恵，生田貴久，成石浩司，永田俊彦，木戸淳一，湯本浩通
- Organizer
  第61回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K15767
[Presentation] 歯肉線維芽細胞においてカルプロテクチン誘導性炎症関連因子の産生に及ぼす高グルコースの影響2018
- Author(s)
  西川康史，成石浩司，木戸淳一，湯本浩通
- Organizer
  第148回日本歯科保存学会春期学術大会
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] ショウガオールはヒト歯肉線維芽細胞におけるAGE誘導性IL-6およびICAM-1産生を抑制する2018
- Author(s)
  野中康平、板東美香、木戸淳一、稲垣裕司、坂本英次郎、成石浩司、湯本浩通
- Organizer
  第61回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11391
[Presentation] 最終糖化産物はヒト歯肉線維芽細胞におけるIL-6とICAM-1の発現増加を介して単球との接着を誘導する2018
- Author(s)
  野中康平、板東美香、木戸淳一、稲垣裕司、坂本英次郎、成石浩司、湯本浩通
- Organizer
  第61回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15K11391
[Presentation] Advanced glycation end-products increase calprotectin in human gingival epithelial cells2017
- Author(s)
  Hiroshima Y, Sakamoto E, Abe K, Yoshida K, Naruishi K, Nagata T, Shinohara Y, Geczy CL, Kido J.
- Organizer
  95th International Association for Dental Research, General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] AGE and Porphyromonas gingivalis-LPS Increase Sclerostin Expression in Osteocytes2017
- Author(s)
  Sakamoto E, Takagi R, Inagaki Y, Naruishi K, Kido J, Nagata T.
- Organizer
  95th International Association for Dental Research, General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] AGE and Porphyromonas gingivalis-LPS Increase Sclerostin Expression in Osteocytes2017
- Author(s)
  2.Sakamoto E, Takagi R, Inagaki Y, Naruishi K, Kido J, Nagata T
- Organizer
  95th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] 最終糖化産物とLPSはMAPKおよびNF-kBを介してマウス骨細胞のスクレロスチンの発現を調節する2017
- Author(s)
  坂本英次郎，稲垣裕司，木戸淳一，高木亮輔，成石浩司，永田俊彦
- Organizer
  第60回春期日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] マウス骨細胞株MLO-Y4-A2のスクレロスチン発現における最終糖化産物およびLPSの影響2017
- Author(s)
  坂本英次郎，稲垣裕司，木戸淳一，高木亮輔，生田貴久，成石浩司，永田俊彦
- Organizer
  第145回日本歯科保存学会春期学術大会
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] Advanced Glycation End-Products Increase Calprotectin in Human Gingival Epithelial Cells2017
- Author(s)
  1.Hiroshima Y, Sakamoto E, Abe K, Yoshida K, Naruishi K, Nagata T, Shinohara Y, Geczy CL, Kido J
- Organizer
  95th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] 最終糖化産物とLPSはMAPKおよびNF-kBを介してマウス骨細胞のスクレロスチンの発現を調節する2017
- Author(s)
  坂本英次郎，稲垣裕司，木戸淳一，高木亮輔，成石浩司，永田俊彦
- Organizer
  第60回春期日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] AGE and Porphyromonas gingivalis-LPS Increase Sclerostin Expression in Osteocytes2017
- Author(s)
  Sakamoto E, Takagi R, Inagaki Y, Naruishi K, Kido J, Nagata T.
- Organizer
  95th International Association for Dental Research, General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] マウス骨細胞株MLO-Y4-A2のスクレロスチン発現における最終糖化産物およびLPSの影響2017
- Author(s)
  坂本英次郎，稲垣裕司，木戸淳一，高木亮輔，生田貴久，成石浩司，永田俊彦
- Organizer
  第145回日本歯科保存学会春期学術大会
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] カルプロテクチンはヒト歯肉線維芽細胞のTLR4を介して炎症性関連因子の発現を亢進する2016
- Author(s)
  西川泰史，成石浩司，梶浦由加里，Lew Jung Hwan，木戸淳一，永田俊彦
- Organizer
  第144回日本歯科保存学会春期学術大会
- Place of Presentation
  栃木県総合文化センター「栃木県宇都宮市」
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-16K11832
[Presentation] 最終糖化産物はヒト歯肉線維芽細胞におけるIL-6およびICAM1の発現を増加する2016
- Author(s)
  8.板東美香，梶浦由加里，野中康平，坂本英次郎，成石浩司，木戸淳一，永田俊彦
- Organizer
  第60回日本歯周病学会秋期学術大会
- Place of Presentation
  朱鷺メッセ、新潟県新潟市
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] マウス骨細胞株MLO-Y4-A2のスクレロスチン発現における最終糖化産物およびLPSの影響2016
- Author(s)
  7.坂本英次郎，稲垣裕司，木戸淳一，高木亮輔，生田貴久，成石浩司，永田俊彦
- Organizer
  第145回日本歯科保存学会春期学術大会
- Place of Presentation
  キッセイ文化ホール、長野県松本市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] High Glucose Enhances IL-6-induced Protease Productions in Gingival Fibroblasts2016
- Author(s)
  5.Lew JH, Naruishi K, Kajiura Y, Nishikawa Y, Kido J, Nagata T
- Organizer
  94th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] カロテノイドは高グルコース下で培養したヒト歯肉線維芽細胞のIL-6誘導性蛋白分解酵素産生を抑制する2016
- Author(s)
  10.Lew Jung Hwan，成石浩司，梶浦由加里，西川泰史，木戸淳一，永田俊彦
- Organizer
  第59回日本歯周病学会春期学術大会
- Place of Presentation
  かごしま県民交流センター、鹿児島県鹿児島市
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] High Glucose Enhances P. gingivalis-induced Cytokine Production in THP-1 Monocytes2016
- Author(s)
  4.Kajiura Y, Naruishi K, Nakajima Y, Nishikawa Y, Lew JH, Kido J, Nagata T
- Organizer
  94th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] High glucose enhances P. gingivalis-induced ctokine production in THP-1 monocytes2016
- Author(s)
  Kajiura Y, Naruishi K, Nakajima Y, Nishikawa Y, Lwe JH, Kido J, Nagata T
- Organizer
  94th General Session of the IADR
- Place of Presentation
  Seoul (Korea)
- Year and Date
  2016-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] Periodontal evaluation using sIL-6R/calprotectin in GCF during SPT phase2016
- Author(s)
  3.Lew JH, Naruishi K, Kajiura Y, Ikuta T, Nishikawa Y, Kido J, Nagata T
- Organizer
  The 102nd Annual Meeting of the American Academy of Periodontology
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] Calprotectin Induces the Expression of Inflammation-related Molecules in Gingival Fibroblasts2016
- Author(s)
  6.Nishikawa Y, Naruishi K, Kajiura Y, Lew JH, Kido J, Nagata T
- Organizer
  94th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] カルプロテクチンはヒト歯肉線維芽細胞のTLR4を介して炎症性関連因子の発現を亢進する2016
- Author(s)
  9.西川泰史，成石浩司，梶浦由加里，Lew Jung Hwan，木戸淳一，永田俊彦
- Organizer
  第144回日本歯科保存学会春期学術大会
- Place of Presentation
  栃木県総合文化センター、栃木県宇都宮市
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] カロテノイドは高グルコース下で培養したヒト歯肉線維芽細胞のIL-6誘導性蛋白分解酵素産生を抑制する2016
- Author(s)
  Lew Jung-Hwan，成石浩司，梶浦由加里，西川泰史，木戸淳一，永田俊彦
- Organizer
  第59回春季日本歯周病学会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] 最終糖化産物は口腔上皮細胞の遺伝子発現を調節する2015
- Author(s)
  坂本英次郎、木戸淳一、梶浦由加里、板東美香、稲垣裕司、成石浩司、生田貴久、永田俊彦
- Organizer
  第58回秋季日本歯周病学会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H05054
[Presentation] 高血糖状態で培養したヒト歯肉線維芽細胞の網羅的な遺伝子解析2011
- Author(s)
  澤田俊輔, 成石浩司
- Organizer
  岩手医科大学歯学会第72回例会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] IL-6によるヒト歯髄細胞のVEGF産生誘導2010
- Author(s)
  藤原英明, 成石浩司, 澤田俊輔, 伊東俊太郎, 八重柏隆, 國松和司
- Organizer
  第133回日本歯科保存学会秋期学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯周病原細菌の感染による全身性炎症性反応に抗する免疫応答の意義2010
- Author(s)
  成石浩司, 園井教裕, 大森一弘, 前田博史, 高柴正悟, 國松和司
- Organizer
  第133回日本歯科保存学会秋期学術大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] IL-1raによるマウス骨芽細胞様細胞MC3T3-E1におけるIL-1誘導性OPGおよびIL-6の産生制御2010
- Author(s)
  久保克行, 大森一弘, 成石浩司, 冨山高史, 小林寛也, 山口知子, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 塗布用ブラシ一体型歯周病薬によるプラークコントロールがSPT期の歯周組織の病状安定に与える影響2010
- Author(s)
  犬伏順也, 安田多賀子, 西田美恵子, 畑中加珠, 成石浩司, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] nrdD様遺伝子の存在は血中移行したPorphyromonas gingivalisの病原性を決定する2010
- Author(s)
  園井教裕, 前田博史, 成石浩司, 苔口進, 大森一弘, 石井真由美, 平井公人, 山部こころ, 谷本一郎, 高柴正悟
- Organizer
  第53回日本歯周病学会秋期学術大会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] MMP-3によるヒト単球系細胞株THP-1からの可溶型IL-6受容体の産生亢進2010
- Author(s)
  小林寛也, 大森一弘, 成石浩司, 山口知子, 冨山高史, 久保克行, 前田博史, 高柴正悟
- Organizer
  第132回日本歯科保存学会春期学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Evaluation of Periodontitis by a Blood Test.2010
- Author(s)
  高柴正悟, 工藤値英子, 成石浩司, 前田博史
- Organizer
  88th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 塗布用ブラシ一体型一般用歯周病薬がSPT期患者の歯肉溝滲出液中サイトカイン量に与える影響2010
- Author(s)
  安田多賀子, 成石浩司, 犬伏順也, 畑中加珠, 前田博史, 高柴正悟
- Organizer
  第53回日本歯周病学会秋期学術大会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] SPT期における歯周組織の維持・改善に対する塗布用ブラシ一体型歯周病薬の効果2010
- Author(s)
  畑中加珠, 成石浩司, 前田博史, 高柴正悟, 犬伏順也, 安田多賀子, 西田美恵子
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯周疾患を標的とした臨床研究と細胞生物学的アプローチ2010
- Author(s)
  成石浩司
- Organizer
  第70回岩手医科大学歯学会例会
- Place of Presentation
  盛岡特別講演
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Inhibition of IL-6/sIL-6R-induced VEGF production by sgp130 in gingival fibroblasts.2010
- Author(s)
  山口知子, 成石浩司, 大森一弘, 前田博史, 高柴正悟
- Organizer
  88th International Association for Dental Research, General Session & Exhibition
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 企業内定期健康診断における歯周病原細菌に対する血清IgG抗体価検査を用いた歯周病スクリーニング効果の統計学的検討2010
- Author(s)
  工藤値英子, 成石浩司, 三橋千代子, 米田哲, 永田俊彦, 佐藤勉, 前田博, 高柴正悟
- Organizer
  第132回日本歯科保存学会春期学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 「歯周組織への感染とそれに対する免疫応答の特異性とは?」歯周病態における体液性免疫応答の成立と意義-IgG抗体産生性に着目して-2010
- Author(s)
  成石浩司
- Organizer
  第53回日本歯周病学会春期学術大会
- Place of Presentation
  盛岡シンポジウム
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 「間葉系幹細胞による歯髄・歯周再生医療の現状と展望～免疫と組織再生の観点から～」歯周組織におけるサイトカインネットワークと再生への展開2010
- Author(s)
  成石浩司
- Organizer
  岩手医科大学歯学部オープンリサーチ・プロジェクト研究成果発表会
- Place of Presentation
  盛岡シンポジウム
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases.2009
- Author(s)
  成石浩司
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases2009
- Author(s)
  Koji Naruishi
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Year and Date
  2009-11-29
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] Perspective Basic and Clinical Research for Periodontal Diseases2009
- Author(s)
  Koji Naruishi
- Organizer
  Association for Dental Sciences of the Republic of China
- Place of Presentation
  Kaohsiung
- Year and Date
  2009-11-29
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] 歯肉線維芽細胞を標的としたカベオリン-1および可溶性gp130によるIL-6誘導性VEGF産生の抑制制御2009
- Author(s)
  山口知子, 成石浩司, 大森一弘, 新井英雄, 高柴正悟
- Organizer
  第130回日本歯科保存学会春期学術大会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20592428
[Presentation] α3β1 integrin-mediated MC3T3-E1 osteoblasts adherence induced by in terleukin-1α2008
- Author(s)
  Takashi Tomiyama, Koji Naruishi, Kazuhiro Omori, Hiroshi Maeda, Shogo Takashiba
- Organizer
  56^<th> Annual Meeting, 2008, Japanese Associationfor Dental Research
- Place of Presentation
  Nagoya
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] ラツト根管治療モデルを用いた根尖周囲組織の遺伝子マイクロアレイ解析に基づいた根尖病巣治癒病態の考察2008
- Author(s)
  冨山高史, 成石浩司, Zulema Arias, 山城圭介, 前田博史, 新井英雄, 高柴正悟
- Organizer
  日本歯科保存学会 2008年春季学術大会(第128回)
- Place of Presentation
  新潟市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20592226
[Presentation] IL-lαおよびIL-1βによるマウス骨芽細胞様細胞MC3T3-E1の動態におけるMAPK系の関与2008
- Author(s)
  冨山高史, 成石浩司, 大森一弘, 久保克行, 前田博史, 新井英雄, 高柴正悟
- Organizer
  第129回日本歯科保存学会秋季学術大会
- Place of Presentation
  富山市
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20592226

1. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 8 results

# of Collaborated Products: 17 results
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# of Collaborated Projects: 5 results

# of Collaborated Products: 24 results
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# of Collaborated Projects: 4 results

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60. 宮本健志

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Naruishi Koji 成石 浩司

成石 浩司 ナルイシ コウジ

NARUISHI Koji 成石 浩司

Research Projects

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Co-Researchers

老齢性テストステロン低下とＡＧＥ上昇に着目した糖尿病関連歯周炎の治療戦略Principal Investigator

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Pathophysiology of periodontitis progression by IL-1 and geriatric impaired testosterone in diabetic patientsPrincipal Investigator

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Crosstalk of Gingival Fibroblasts and Macrophages in Inflammatory Cytokine Cascade: Potential Mechanisms of Periodontitis with Diabetes.Principal Investigator

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ＡＰ－１によるカテプシン産生制御に着目した歯肉増殖症・歯周病診断の新機軸Principal Investigator

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Possible Mechanisms of Progression of Periodontits by MMP-3 in Diabetic PatientsPrincipal Investigator

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Naruishi Koji 成石浩司

成石浩司ナルイシコウジ

NARUISHI Koji 成石浩司