OHYAMA Hideki 大山秀樹

Researcher Number	90280685
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2021 – 2022: 大阪医科薬科大学, 医学部, 非常勤講師 2016 – 2020: 大阪医科大学, 医学部, 非常勤講師 2016: 兵庫医科大学, 医学部, 准教授 2014 – 2016: 兵庫医科大学, 医学部, 非常勤講師 2010 – 2013: Hyogo College of Medicine, 医学部, 准教授 … More 2006 – 2009: 兵庫医科大学, 医学部, 講師 2004: Hyogo College of Medicine, Faculty of Medicine, Assistant Professor, 医学部, 講師 2002 – 2003: 埼玉医科大学, 医学部, 講師 2001: 岡山大学, 大学院・医歯学総合研究科, 助手 1999 – 2000: 岡山大学, 歯学部, 助手 1997 – 1998: (財)大阪皮膚病研究会, 研究員 Less
Review Section/Research Field	Principal Investigator Periodontal dentistry / Periodontal dentistry / Periodontology / Conservative dentistry Except Principal Investigator Experimental pathology / Periodontal dentistry / Periodontal dentistry / Periodontology / Conservative dentistry / Basic Section 57020:Oral pathobiological science-related / Conservative dentistry / Orthopaedic surgery / Digestive surgery
Keywords	Principal Investigator IL-22 / サイトカイン / 樹状細胞 / 歯肉線維芽細胞 / T細胞 / 歯周病 / keratinocytes / T cells / β-defensin / periodontitis … More / β-ディフェンシン2,3 / ケラチノサイト / β-ディフェンシン / 歯周炎 / immune therapy / periodontal bacteria / dendritic cells / T cell lines / glycolipid antigens / 免疫療法 / 歯周病細菌 / T細胞株 / 糖脂質抗原 / ＩＬ－３６ / 歯肉上皮細胞 / IL-36 / ヒト歯根膜由来細胞 / ＩＬ－２２ / 歯根膜由来細胞 / 石灰化誘導 / 歯根膜細胞 / クラスIIHLA分子 / クテスII HLA分子 / クラスII HLA分子 / ヘルパーT細胞 / 抗原認識 / Th細胞株 / ペプチド免疫療法 / HLA / T細胞エピトープ / Omp34 / T細胞認識 / ケモカイン / HLA拘束性 / HLAクラスII分子 / 歯根膜線維芽細胞 / HLA class II分子 / T細胞応答 / 早期発症型歯周炎 / INF-α / IFN-γ / 免疫応答 / ハンセン病 … More Except Principal Investigator 歯周病 / 骨肉腫 / vascular endothelial growth factor / Porphyromonas gingivalis / IL-22 / 歯肉上皮細胞 / 腫瘍溶解アデノウイルス / 腫瘍溶解ウイルス / 転移 / インターロイキン18 / 免疫療法 / 口腔粘膜炎 / 化学療法 / IgA抗体 / 口腔細菌叢 / インターロイキン２２ / 間葉系幹細胞 / 歯根嚢胞 / leukocyte / bacterial detection / periodontal desease / oral infection control / compromised host / PBSCT / 白血球数 / 細菌検査 / 歯周疾患 / 口腔管理 / 易感染性宿主 / 末梢血幹細胞移植 / single nucleotide polymorphism / drug metabolizing enzyme / anti-angiogenic effect / deficient mice / cathepsin-L / lysosomal enzymes / drug-induced gingival overgrowth / I-cell病 / サイクロスポリン / ニフェジピン / 表現型 / 欠損マウス / カテプシン / 免疫抑制剤 / 抗てんかん薬 / Ca拮抗剤 / Dose(D)ratio / Concentration(C) / CYP2C19 / CYP2C9 / チトクロームP450 / フェニトイン / 薬物代謝 / 遺伝子多型 / 薬物代謝酵素 / 血管新生抑制作用 / 遺伝子欠損マウス / カテプシン-L / ライソゾーム酵素 / 薬物性歯肉増殖症 / Cytokines / HLA class II / T cell epitopes / 53kDa outer membrane protein / リンフォカイン / HLA classII / ヘルパパーT細胞 / Porphyromonas gingiralis / サイトカイン / HLA class V / T細胞エピトープ / 53kDa外膜蛋白 / 抗菌ペプチド / 歯周病細菌 / P.gingivalis / ＩＬ－２２ / 細胞内侵入細菌 / 癌標的化 / 大腸癌 / 悪性中皮腫 / インビボ分子イメージング / 腫瘍溶解療法 / 癌遺伝子治療 / ウイルス療法 / 癌 / 遺伝子治療 / eGFR / lipocalin-2 / マイクロアレイ / 共培養 / 心腎連関 / メサンギウム / CKD / 膵ベータ細胞 / 膵アルファ細胞 / 脂肪組織炎症 / 樹状細胞 / 膵β細胞 / 膵α細胞 / 歯周炎症 / インスリン抵抗性 / 肥満 / 内毒素 / 細胞死 / 膵島炎症 / 脂肪炎症 / ケモカイン / 脂肪細胞－マクロファージ相互作用 / 軽微な慢性炎症 / 歯周医学 / 非ステロイド系抗炎症剤 / 薬剤耐性 / ＡＰＲＩＬ / ＢＡＦＦ / CCL22 / CCL17 / 歯肉線維芽細胞 / EGFR / Immunogenic cell death / Oncolytic virus / 癌ワクチン / インターロイキン / Treg細胞 / Th17細胞 / ヘルパーT細胞 / 制御性T細胞 / IL-35 / 腫瘍 / 血清IgG抗体価 / 肝機能マーカー / 歯周炎 / 脂肪性肝炎 / 歯周免疫機能学 / アミノ酸置換ペプチド / 合成ペプチド / 交叉応答 / T細胞クローン / 予防ワクチン / う蝕 Less

IgA response associated with the oral microbiota of chemotherapy-induced oral mucositis.
- Principal Investigator
  
  kato-kooge nahoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Potential role of interleukin-22 in the pathogenesis of periapical cysts
- Principal Investigator
  
  Kato-Kogoe Nahoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka Medical College
Potential role of IL-1 family cytokines in periodontal diseasesPrincipal Investigator
- Principal Investigator
  
  Ohyama Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka Medical College
  Hyogo Medical University
Effect of IL-22 on immune response against periodontal bacteria
- Principal Investigator
  
  Kato-kogoe Nahoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Osaka Medical College
  Hyogo Medical University
Molecular basis for periodontal medicine based on the interaction between infiltrated inflammatory cells and resident cells.
- Principal Investigator
  
  NISHIMURA FUSANORI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Kyushu University
Development of oncolytic adenovirus as a new therapeutic agent for treating disseminated cancers
- Principal Investigator
  
  Kubo Shuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hyogo Medical University
Inhibition of inducing multidrug resistance in human osteosarcoma cells by histone deacetylase inhibitor and DNA methylation inhibitor
- Principal Investigator
  
  TERADA NOBUYUKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hyogo Medical University
Identification and the elucidation of the mechanism of interleukin 18 induced metastasis inhibitory factor(s)
- Principal Investigator
  
  YAMADA Naoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hyogo Medical University
Development of a novel cancer vaccine using chemokine CCL21 and oncolytic adenovirus
- Principal Investigator
  
  YAMANO Tomoki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hyogo Medical University
The effect of IL-22 on biological activity of periodontal ligament cellsPrincipal Investigator
- Principal Investigator
  
  OHYAMA hideki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hyogo Medical University
The effect of EGF receptor pathway on cytokine production in gingival fibroblasts
- Principal Investigator
  
  KOGOE Nahoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Himeji Dokkyo University
Identification of IL-18-induced Tumor-Cell Migration Inhibitory Factor(s) and Elucidation of its Action Mechanism..
- Principal Investigator
  
  YAMADA Naoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hyogo College of Medicine
A study on the effects of products from non-hemocyte cells activated by crosslinking HLA-II molecules on Th-cell differentiation in periodontal diseasesPrincipal Investigator
- Principal Investigator
  
  OHYAMA Hideki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hyogo College of Medicine
The effects of IL-35 on periodontal diseases
- Principal Investigator
  
  KOGOE Nahoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hyogo College of Medicine
A study on the effect of periodontal diseases on the onset and progression of steatohepatitis.
- Principal Investigator
  
  NAKASHO Keiji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hyogo College of Medicine
A study for the involvement of IL-22 in the pathogenesis of periodontal diseasesPrincipal Investigator
- Principal Investigator
  
  OHYAMA Hideki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hyogo College of Medicine
A basic studies to develop the immune therapy for periodontal diseases by employing glycolipids derived from periodontal bacteria as antigens.Principal Investigator
- Principal Investigator
  
  OHYAMA Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hyogo College of Medicine
  Saitama Medical University
若年性歯周炎患者の疾患感受性を規定するA.a外膜蛋白のT細胞エピトープの同定Principal Investigator
- Principal Investigator
  
  大山秀樹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Saitama Medical University
  Okayama University
Study on the pathogenesis of drug-induced gingival overgrowth -A study with deficient mice
- Principal Investigator
  
  NISHIMURA Fusanori
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study for oral infectious control during peripheral blood stem cell transplantation
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
歯周病の発症と進行に関わる交叉免疫応答を誘導する抗原蛋白
- Principal Investigator
  
  村山洋二
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
歯根膜線維芽細胞に発現するHLAクラスII分子のレセプター分子としての役割Principal Investigator
- Principal Investigator
  
  大山秀樹
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
う蝕・歯周病予防ワクチン開発に向けての新たな戦略
- Principal Investigator
  
  苔口進
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
免疫学的側面から見たハンセン病患者の歯周病の病態解析Principal Investigator
- Principal Investigator
  
  大山秀樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Conservative dentistry
- Research Institution
  Osaka Dermatological Institute
Basic studies on adaptation the immune therapy to the patients with periodontal diseases by using synthetic peptides as an immunogen
- Principal Investigator
  
  MURAYAMA Yoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama university

[Book] Leprosy-Science working towards dignity2011
- Author(s)
  Hideki Ohyama
- Publisher
  Tokai University Press
- Data Source
  KAKENHI-PROJECT-20592443
[Book] Leprosy-Science working towards dignity2011
- Author(s)
  Hideki Ohyama
- Publisher
  Tokai University Press
- Data Source
  KAKENHI-PROJECT-23593076
[Book] Leprosy-Science working towards dignity.(Ed : Makino M, Matsuoka M, Goto M, Hatano K)(Chapter 8. Immunogenetics.)2011
- Author(s)
  大山秀樹
- Publisher
  Tokai University Press, Kanagawa
- Data Source
  KAKENHI-PROJECT-20592443
[Book] Leprosy2010
- Author(s)
  Hideki Ohyama
- Publisher
  Tokai University Press(in press)
- Data Source
  KAKENHI-PROJECT-20592443
[Book] エンド難症例・メカニズムと臨床応用(恵比須繁之編)(Chapter5エンド治療に関連するトピック歯内疾患と全身の健康)2009
- Author(s)
  大山秀樹,小越菜保子
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20592443
[Book] 「総説現代ハンセン病医学」:第1部基礎医学の進歩第4章ハンセン病の免疫遺伝学2007
- Author(s)
  大山秀樹, 大谷藤郎監修
- Total Pages
  471
- Publisher
  東海大学出版会(神奈川)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] Iron-induced calcification in human aortic vascular smooth muscle cells through interleukin-24 (IL-24), with/without TNF-alpha2018
- Author(s)
  Kawada Sayuri、Nagasawa Yasuyuki、Kawabe Mutsuki、Ohyama Hideki、Kida Aritoshi、Kato-Kogoe Nahoko、Nanami Masayoshi、Hasuike Yukiko、Kuragano Takahiro、Kishimoto Hiromitsu、Nakasho Keiji、Nakanishi Takeshi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 658-658
- DOI
  10.1038/s41598-017-19092-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11727, KAKENHI-PROJECT-16K09661
[Journal Article] Functional analysis of differences in transcriptional activity conferred by genetic variants in the 5' flanking region of the IL12RB2 gene.2016
- Author(s)
  Kato-Kogoe N, Ohyama H, Okano S, Yamanegi K, Yamada N, Hata M, Nishiura H, Abiko Y, Terada N, Nakasho K
- Journal Title
  
  Immunogenetics
  
  Volume: 68(1) Issue: 1 Pages: 55-65
- DOI
  10.1007/s00251-015-0882-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26463150, KAKENHI-PROJECT-26463151
[Journal Article] Expression of interleukin-34 and colony stimulating factor-1 in the stimulated periodontal ligament cells with tumor necrosis factor-α.,2015
- Author(s)
  Kawabe M, Ohyama H, Kato-Kogoe N, Yamada N, Yamanegi K, Nishiura H, Hirano H, Kishimoto H, Nakasho K.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26463150
[Journal Article] Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.2015
- Author(s)
  Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasyo K, Nakase I, Futaki S, Tohyama Y, Hirose M
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 765 Pages: 24-33
- DOI
  10.1016/j.ejphar.2015.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26463151
[Journal Article] Expression of interleukin-34 and colony stimulating factor-1 in the stimulated periodontal ligament cells with tumor necrosis factor-α.2015
- Author(s)
  Kawabe M, Ohyama H, Kato-Kogoe N, Yamada N, Yamanegi K, Nishiura H, Hirano H, Kishimoto H, Nakasho K.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592247
[Journal Article] Estrogen decreases the expression of claudin-5 in vascular endothelial cells in the murine uterus.2014
- Author(s)
  Hata M, Yamanegi K, Yamada N, Ohyama H, Yukitatsu Y, Nakasho K, Okamura H, Terada N.
- Journal Title
  
  Endocr J
  
  Volume: -
- NAID
  130004443978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590480
[Journal Article] Expression of interleukin-34 and colony stimulating factor-1 in the stimulated periodontal ligament cells with tumor necrosis factor-α2014
- Author(s)
  Kawabe M, Ohyama H, Kato-Kogoe N, Yamada N, Yamanegi K, Nishiura H, Hirano H, Kishimoto H, Nakasho K.
- Journal Title
  
  Med Mol Morphol
  
  Volume: 25 Issue: 3 Pages: 54-68
- DOI
  10.1007/s00795-014-0094-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462863, KAKENHI-PROJECT-26463150, KAKENHI-PROJECT-26463151
[Journal Article] Estrogen decreases the expression of claudin-5 in vascular endothelial cells in the murine uterus.2014
- Author(s)
  Hata M, Yamanegi K, Yamada N, Ohyama H, Yukitatsu Y, Nakasho K, Okamura H, Terada N.
- Journal Title
  
  Endocr J
  
  Volume: -
- NAID
  130004443978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592247
[Journal Article] Decreased expression of VE-cadherin and claudin-5 and increased phosphorylation of VE-cadherin in vascular endothelium in nasal polyps.2013
- Author(s)
  Yukitatsu Y, Hata M, Yamanegi K, Yamada N, Ohyama H, Nakasho K, Kojima Y, Oka H, Tsuzuki K, Sakagami M, Terada N.
- Journal Title
  
  Cell Tissue Res
  
  Volume: 352 Issue: 3 Pages: 647-657
- DOI
  10.1007/s00441-013-1583-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590480, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-24592247, KAKENHI-PROJECT-25462671, KAKENHI-PROJECT-23792159
[Journal Article] T-cell Responses Involved in the Predisposition to Periodontal Disease: Lessons from Immunogenetic Studies of Leprosy2013
- Author(s)
  Hideki Ohyama, Nahoko Kato-Kogoe, Kazu Takeuchi-Hatanaka, Koji Yamanegi, Naoko Yamada, Keiji Nakasho, Sho Matsushita and Nobuyuki Terada
- Journal Title
  
  J Clin Cell Immunol
  
  Volume: S1 Pages: 1-7
- DOI
  10.4172/2155-9899.s1-005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593058, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-23593077
[Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.2013
- Author(s)
  Kuroda Y, Kato-Kogoe N, Tasaki E, Murata M, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 698 Issue: 1-3 Pages: 87-94
- DOI
  10.1016/j.ejphar.2012.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390297, KAKENHI-PROJECT-22590076, KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23593077, KAKENHI-PROJECT-23700588, KAKENHI-PROJECT-23790129
[Journal Article] The promotional effect of IL-22 on mineralization activity of periodontal ligament cells2012
- Author(s)
  Kato-Kogoe N, Nishioka T, Kawabe M, Kataoka F, Yamanegi K, Yamada N, Hata M, Yamamoto T, Nakasho K, Urade M, Terada N, Ohyama H
- Journal Title
  
  Cytokine
  
  Volume: 59(1) Issue: 1 Pages: 41-8
- DOI
  10.1016/j.cyto.2012.03.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590480, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-23593077, KAKENHI-PROJECT-23792159
[Journal Article] The promotional effect of IL-22 on mineralization activity of periodontal ligament cells.2012
- Author(s)
  Kato-Kogoe N, Nishioka T, Kawabe M, Kataoka F, Yamanegi K, Yamada N, Hata M, Yamamoto T, Nakasho K, Urade M, Terada N, Ohyama H.
- Journal Title
  
  Cytokine.
  
  Volume: Apr 24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593077
[Journal Article] Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death.2012
- Author(s)
  Yamanegi K, Yamane J, Kobayashi K, Kato-Kogoe N, Ohyama H, Nakasho K, Yamada N, Hata M, Fukunaga S, Futani H, Okamura H, Terada N.
- Journal Title
  
  Int J Oncol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593077
[Journal Article] Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells.2012
- Author(s)
  Yamanegi K, Yamane J, Kobayashi K, Ohyama H, Nakasho K, Yamada N, Hata M, Fukunaga S, Futani H, Okamura H, Terada N.
- Journal Title
  
  Oncol Rep.
  
  Volume: 28(5) Issue: 5 Pages: 1585-1590
- DOI
  10.3892/or.2012.1981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591671, KAKENHI-PROJECT-23590480, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-24592247, KAKENHI-PROJECT-23792159
[Journal Article] Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma2012
- Author(s)
  Yamanegi K, Yamane J, Kobayashi K, Kato-Kogoe N, Ohyama H, Nakasho K, YamadaN, Hata M, Fukunaga S, Futani H, Okamura H, Terada N.
- Journal Title
  
  cells to Fas- and NK cell-mediated cell death.Int J Oncol.
  
  Volume: 41(1) Pages: 83-91
- DOI
  10.3892/ijo.2012.1438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591671, KAKENHI-PROJECT-23590480, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-23593077, KAKENHI-PROJECT-24390306, KAKENHI-PROJECT-24592247, KAKENHI-PROJECT-23792159
[Journal Article] Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1α-dependent manner.2012
- Author(s)
  Yamada N, Yamanegi K, Ohyama H, Hata M, Nakasho K, Futani H, Okamura H, Terada N.
- Journal Title
  
  Int J Oncol.
  
  Volume: 41(6) Issue: 6 Pages: 2005-2012
- DOI
  10.3892/ijo.2012.1630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591671, KAKENHI-PROJECT-23590480, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-24390306, KAKENHI-PROJECT-24592247, KAKENHI-PROJECT-23792159
[Journal Article] Adipocyte-macrophage interaction may mediate LPS-induced low-grade inflammation : potential link with metabolic complications.2011
- Author(s)
  Nakarai H., Yamashita A., Nagayasu S., Iwashita M., Kumamoto, S., Ohyama H., Hata M., Soga Y., Kushiyama A., Asano T., Abiko Y., Nishimura F.
- Journal Title
  
  Innate Immunity (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Phenotypic characteristics and proliferative activity of hyperplastic ductile cells in cholangiofibrosis induced by thioacetamide in rats. Epub ahead of print2011
- Author(s)
  Hata M, Iida H, Yamanegi K, Yamada N, Ohyama H, Hirano H, Nakasho K, Terada N.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590480
[Journal Article] T細胞応答性から捉えた歯周病に対する疾患感受性の個体差に関する免疫遺伝学的研究2010
- Author(s)
  大山秀樹
- Journal Title
  
  日本歯周病学会会(日本歯周病学会学術賞受賞記念総説)誌 52
  
  Pages: 14-23
- NAID
  10027096058
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Clinical and immunological assessment of periodontal disease in Japanese leprosy patients.2010
- Author(s)
  Ohyama H
- Journal Title
  
  Japanese Journal Of Infectious Diseases
  
  Volume: 63(6) Pages: 427-432
- NAID
  40017386094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligands, MICA/B, without increasing their soluble forms to enhance susceptibility of human osteosarcoma cells to NK cell-mediated cytotoxicity.2010
- Author(s)
  Yamanegi K, Yamane J, Kobayashi K, Kato-Kogoe N, Ohyama H, Nakasho K, Yamada N, Hata M, Nishioka T, Fukunaga S, Futani H, Okamura H, Terada N
- Journal Title
  
  Oncol Rep. 24(6)
  
  Pages: 1621-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article]2010
- Author(s)
  Yamanegi K., Yamane J., Kobayashi K., Kato-Kogoe N., Ohyama H., Nakasho K., Yamada N., Hata M., Nishioka T., Fukunaga S., Futani H., Okamura H., Terada N.
- Journal Title
  
  Oncology Reports 24
  
  Pages: 1621-1627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Fibroblasts stimulated via HLA-II molecules produce prostaglandin E(2) and regulate cytokine production from helper T cells.2010
- Author(s)
  Kato-Kogoe N, Ohyama H, Nakasho K, Yamanegi K, Yamada N, Terada N, et al.
- Journal Title
  
  Lab Invest.
  
  Volume: 90 Pages: 1747-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] Clinical and immunological assessment of periodontal disease in Japanese leprosy patients.2010
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Japanese Journal of Infectious Diseases
  
  Volume: 63 Pages: 427-432
- NAID
  40017386094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Fibroblasts stimulated via HLA-II molecules produce prostaglandin E(2) and regulate cytokine production from helper T cells.2010
- Author(s)
  Kato-Kogoe N, Ohyama H, Nishimura F, Meguro M, Yoshizawa S, Okada Y, Nakasho K, Yamanegi K, Yamada N, Hata M, Higashi T, Terada N, Matsushita S
- Journal Title
  
  Lab Invest. 90(12)
  
  Pages: 1747-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] Fibroblasts stimulated via HLA-II molecules produce prostaglandin E2 and regulate cytokine production from helper T cells.2010
- Author(s)
  Kato-Kogoe N., Ohyama H., Nishimura F., Meguro M., Yoshizawa S., Okada Y., Nakasho K., Yamanegi K., Yamada N., Hata M., Higashi T., Terada N., Matsushita S.
- Journal Title
  
  Lab.Invest. 90
  
  Pages: 1747-1756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Fibroblasts stimulated via HLA-II molecules produce prostaglandin E_2 and regulate cytokine production from helper T cells.2010
- Author(s)
  Kato-Kogoe N, Ohyama H, Nishimura F, Meguro M, Yoshizawa S, Okada Y, Nakasho K, Yamanegi K, Yamada N, Hata M, Higashi T, Terada N, Matsushita S.
- Journal Title
  
  Lab Invest. 90(12)
  
  Pages: 1747-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] T細胞応答性から捉えた歯周病に対する疾患感受性の個体差に関する免疫遺伝学的研究.2010
- Author(s)
  大山秀樹
- Journal Title
  
  日本歯科周病学会会誌 52
  
  Pages: 14-23
- NAID
  10027096058
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligands, MICA/B, without increasing their soluble forms to enhance susceptibility of human osteosar coma cells to NK cell-mediated cytotoxicity.2010
- Author(s)
  Yamanegi K, Yamane J, Kobayashi K, Kato-Kogoe N, Ohyama H, Nakasho K, Yamada N, Terada N, et al.
- Journal Title
  
  Oncol Rep.
  
  Volume: 24 Pages: 1621-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] Clinical and Immunological Assessment of Periodontal Disease in Japanese Leprosy Patients.2010
- Author(s)
  Ohyama H., Hongyo H., Shimizu N., Shimizu Y., Nishimura F., Nakagawa M., Arai H., Kato-Kogoe N., Terada N., Nagai A., Takashiba S., Kurihara H., Nomura Y., Murayama Y.
- Journal Title
  
  Jpn.J.Infect.Dis. 63
  
  Pages: 427-432
- NAID
  40017386094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] The involvement of IL-23and Th17 pathway in periodontitis.2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Dental Research 88
  
  Pages: 633-638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] An unusual autopsy case of pyogenic liver abscess caused by periodontal bacteria.2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Japaness Journal of Infectious Diseases 62(5)
  
  Pages: 381-383
- NAID
  40016750210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] The involvement of IL-23 and Th17 pathway in periodontitis.2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Dental Research (in press)
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] The involvement of IL-23 and Th17 pathway in periodontitis2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Dental Research 88(7)
  
  Pages: 633-638
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] An unusual autopsy case of pyogenic liver abscess caused by periodontal bacteria.2009
- Author(s)
  Ohyama H., Nakasho K., Yamanegi K., Noiri Y., Kuhara A., Kato-Kogoe K., Yamada N., Hata M., Nishimura F., Ebisu S., Terada N.
- Journal Title
  
  Jpn.J.Infect.Dis. 62
  
  Pages: 381-383
- NAID
  40016750210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] An unusual autopsy case of pyogenic liver abscess caused by periodontal bacteria.2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Japanese Journal of Infectious Diseases 62
  
  Pages: 381-383
- NAID
  40016750210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] The Involvement of IL-23 and the Th17 Pathway in Periodontitis.2009
- Author(s)
  Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N
- Journal Title
  
  J Dent Res. 88(7)
  
  Pages: 633-8
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] The involvement of IL-23 and the Th17 pathway in periodontitis.2009
- Author(s)
  Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N.
- Journal Title
  
  J Dent Res. 88(7)
  
  Pages: 633-8
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] The involvement of IL-23 and Th17 pathway in periodontitis.2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Dental Research (in press)
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] The involvement of IL-23 and the Th17 pathway in periodontitis2009
- Author(s)
  Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N
- Journal Title
  
  J Dent Res 88
  
  Pages: 633-638
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] Immunotherapy with Interleukin-18 in Combination with Preoperative Chemotherapy with Ifosfamide Effectively Inhibits Postoperative Progression of Pulmonary Metastases in a Mouse Osteosarcoma Model.2009
- Author(s)
  Yamada N, Hata M, Ohyama H, Yamanegi K, Kogoe N, Nakasho K, Futani H, Okamura H, Terada N
- Journal Title
  
  Tumour Biol. 30(4)
  
  Pages: 176-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] HLA-II-induced cytokines from human gingical fibroblasts promotes proliferation of human umbilical vein endothelial (HUVEC) cells : potential association with enhanced angiogenesis in chronic periodontal inflammation.2009
- Author(s)
  Okada Y., Meguro M., Ohyama H., Yoshizawa S., Takeuchi-Hatanaka K., Kato N., Matsushita S., Takashiba S., Nishimura F.
- Journal Title
  
  J.Periodont.Res. 44
  
  Pages: 103-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Genetic Risk Factor for Periodontitis in a Japanese Population.2009
- Author(s)
  Kobayashi T., Nagata T., Murakami S., Takashiba S., Kurihara H., Izumi Y., Numabe Y., Watanabe H., Kataoka M., Nagai A., Hayashi J., Ohyama H., Okamatsu Y., Inagaki Y., Tai H., Yoshie H.
- Journal Title
  
  J.Dent.Res. 88
  
  Pages: 1137-1141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] The Involvement of IL-23 and the Th17 Pathway in Periodontitis.2009
- Author(s)
  Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, et al.
- Journal Title
  
  J Dent Res. 88
  
  Pages: 633-8
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] The involvement of IL-23 and Th17 pathway in periodontitis.2009
- Author(s)
  Ohyama H., Kato-Kogoe N., Kuhara A., Nishimura F., Nakasho K., Yamanegi K., Yamada N., Hata M., Yamane J., Terada N.
- Journal Title
  
  J.Dent.Res. 88
  
  Pages: 633-638
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] An unusual autopsy case of pyogenic liver abscess caused by periodontal bacteria2009
- Author(s)
  Ohyama H, Nakasho K, Yamanegi K, Noiri Y, Kuhara A, Kato-Kogoe N, Yamada N, Hata M, Nishimura F, Ebisu S, Terada N
- Journal Title
  
  Jpn J Infect Dis 62
  
  Pages: 381-383
- NAID
  40016750210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] The involvement of IL-23 and Th17 pathway in periodontitis2009
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Dental Research (In press)
- NAID
  130004570957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] Role of human non-invariant NKT lymphocytes in the maintenance of type 2 T helper environment during pregnancy.2008
- Author(s)
  Uemura Y., Suzuki M., Liu T.Y., Narita Y., Hirata S., Ohyama H., Ishihara O., Matsushita S.
- Journal Title
  
  Int.Immunol. 20
  
  Pages: 405-412
- NAID
  10021239996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Polymorphisms in the 5' flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population.2008
- Author(s)
  Takeuchi-Hatanaka K., Ohyama H., Nishimura F., Kato-Kogoe N., Soga Y., Matsushita S., Nakasho K., Yamanegi K., Yamada N., Terada N., Takashiba S.
- Journal Title
  
  J.Clin.Periodontol. 35
  
  Pages: 317-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Differential effects of polymorphisms in the 5' flanking region of IL12RB2 on NK- and T-cell activity.2008
- Author(s)
  Ohyama H, Kato-Kogoe N, Nishimura F, Takeuchi-Hatanaka K, Matsushita S, Yamanegi K, Yamada N, Hata M, Nakasho K, Terada N
- Journal Title
  
  J Interferon Cytokine Res. 28(9)
  
  Pages: 563-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] Enhanced suppression of pulmonary metastasis of malignant melanoma cells by combined administration of alpha-galactosylceramide and interleukin-18.2008
- Author(s)
  Nishio S., Yamada N., Ohyama H., Yamanegi K., Nakasho K., Hata M., Nakamura Y., Fukunaga S., Futani H., Yoshiya S., Ueda H., Taniguchi M., Okamura H., Terada N.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 113-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Enhanced suppression of pulmonary metastasis of malignant melanoma cells by combined administration of alpha- galactosylceramide and interleukin-18.2008
- Author(s)
  Nishio S, Yamada N, Ohyama H, Yamanegi K, Nakasho K, Hata M, Nakamura Y, Fukunaga S, Futani H, Yoshiya S, Ueda H, Taniguchi M, Okamura H, Terada N
- Journal Title
  
  Cancer Sci. 99(1)
  
  Pages: 113-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] Differential effects of polymorphisms in the 5' flanking region of IL12RB2 on NK and T cell activity.2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Interferon & Cytokine Research 28
  
  Pages: 563-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Polymorphisms in the 5'flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population.2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Periodontal Research 35(4)
  
  Pages: 317-323
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] Differential effect of polymorphisms in the 5' flanking region of IL12RB2 on NK- and T-cll activity.2008
- Author(s)
  Ohyama H., Kato-Kogoe N., Nishimura F., Takeuchi-Hatanaka K., Matsushita S., Yamanegi K., Yamada N., Hata M., Nakasho K., Terada N.
- Journal Title
  
  J.Interferon Cytokine Res. 28
  
  Pages: 563-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Differential effects of polymorphisms in the 5' flanking region of IL12RB2 on NK and T cell activity.2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Interferon & Cytokine Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] 胆嚢Mucin-producing papillary adenocarcinomaの1例2008
- Author(s)
  中正恵二, 覚野綾子, 大山秀樹, 山根木康嗣, 山田直子, 秦正樹, 平野博嗣, 寺田信行, 相原司, 安井智明, 山中若樹
- Journal Title
  
  診断病理 25
  
  Pages: 104-111
- NAID
  10021252127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] Polymorphisms in the 5'flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Clinical Periodontology 35(4)
  
  Pages: 317-323
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] Polymorphisms in the 5' flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population2008
- Author(s)
  Takeuchi-Hatanaka, K., Ohyama, H., Nishimura, F., Kato-Kogoe, N., Soga, Y., Matsushita, S., Nakasho, K., Yamanegi, K., Yamada, N., Terada, N., Takashiba, S
- Journal Title
  
  J. Clin. Periodontol 35
  
  Pages: 317-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] 胆嚢hepatoid adenocarcinomaの1例2008
- Author(s)
  中正恵二, 山根木康嗣, 大山秀樹, 平野博嗣, 山田直子, 秦正樹, 寺田信行, 岡田敏弘, 斉藤慎一, 藤元治朗
- Journal Title
  
  診断病理 25
  
  Pages: 210-217
- NAID
  10021930362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] Histochemical demonstration of aluminum and iron deposition in pulmonary bony tissues in three cases of diffuse pulmonary ossification.2008
- Author(s)
  Ohtsuki Y., Yamanaka A., Ohyama H., Yamada E., Terada N., Fujita J., Lee G.H., Furihata M.
- Journal Title
  
  Histol.Histopathol. 23
  
  Pages: 137-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Transdifferentiation into biliary ductular cells of hepatocytes transplanted into the spleen2008
- Author(s)
  Watanabe, H., Hata, M., Terada, N., Ueda, H., Yamada, N., Yamanegi, K., Ohyama, H., Kakihana, M., Okamura, H., Nakasho, K
- Journal Title
  
  Pathology 40
  
  Pages: 272-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.2008
- Author(s)
  Liu T.Y., Uemura Y., Suzuki M., Narita Y., Hirata S., Ohyama H., Ishihara O., Matsushita S.
- Journal Title
  
  Eur.J.Immunol. 38
  
  Pages: 1012-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Differential effect of polymorphisms in the 5'flanking region of IL12RB2 on NK-and T-cell activity2008
- Author(s)
  Ohyama, H., Kato-Kogoe, N., Nishimura, F., Takeuchi-Hatanaka, K., Matsushita, S., Yamanegi, K., Yamada, N., Hata, M., Nakasho, K., Terada, N
- Journal Title
  
  J. Interferon Cytokine Res 28
  
  Pages: 563-569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] Transdifferentiation into biliary ductular cells of hepatocytes transplanted into the spleen.2008
- Author(s)
  Watanabe H., Hata M., Terada N., Ueda H., Yamada N., Yamanegi K., Ohyama H., Kakihana M., Okamura H., Nakasho K.
- Journal Title
  
  Pathology 40
  
  Pages: 272-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592443
[Journal Article] Differential effects of polymorphisms in the 5' flanking region of IL12R B2 on NK and T cell activity2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Interferon & Cytokine Research 28(9)
  
  Pages: 563-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20599020
[Journal Article] Differential effects of polymorplusms in the 5' flanking region of IL12RB2 on,NK and T cell activity2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Interferon&Cytokine Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] Sodium valproate, a histone deacetylase inhibitor, decreases the secretion of soluble Fas by human osteosarcoma cells and increases their sensitivity to Fas-mediated cell death.2008
- Author(s)
  Yamanegi K, Yamane J, Hata M, Ohyama H, Yamada N, Kato-Kogoe N, Futani H, Nakasho K, Okamura H, Terada N
- Journal Title
  
  J Cancer Res Clin Oncol. 135(7)
  
  Pages: 879-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590414
[Journal Article] Differential effects of polymorphisms in the 5' flanking region of IL12RB2 on NK and T cell activity2008
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Interferon & Cytokine Research (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] 転移性肝平滑筋肉腫切除および動注化学療法後の区域胆管壊死の1剖検例2007
- Author(s)
  中正恵二, 大山秀樹, 山根木康嗣, 山田直子, 秦正樹, 平野博嗣, 寺田信行, 吉田康彦, 斉藤慎一, 藤元治朗
- Journal Title
  
  診断病理 24
  
  Pages: 77-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592399
[Journal Article] ハンセン病に対する感受性および病型形成に関わる免疫遺伝学的背景2006
- Author(s)
  大山秀樹
- Journal Title
  
  化学療法の領域 22(9)
  
  Pages: 71-77
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] ハンセン病に対する感受性および病型形成に関わる免疫遺伝学的背景2006
- Author(s)
  大山秀樹
- Journal Title
  
  化学療法の領域 22
  
  Pages: 71-77
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] びまん性肺骨形成(diffuse puhnonary ossification;DPO)の一例2006
- Author(s)
  大山秀樹
- Journal Title
  
  診断病理 23(4)
  
  Pages: 266-270
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592274
[Journal Article] Role of helper T cells in the humoral immune responses against 53-kDa outer membrane protein from Porphyromonas gingivalis.2005
- Author(s)
  Kato, N., Ohyama, H., Nishimura, F., Matsushita, S., Takashiba, S., Murayama, Y.
- Journal Title
  
  Oral Microbiology and Immunology 20(2)
  
  Pages: 112-117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Polymorphism of the 5' flanking region of the IL-12 receptor β2 gene partially determines the clinical types of leprosy through impaired transcriptional activity.2005
- Author(s)
  Ohyama, H., Ogata, K., Takeuchi, K., Namisato, M., Fukutomi, Y., Nishimura, F., Naruishi, H., Ohira, T., Hashimoto, K., Liu, T., Suzuki, M., Uemura, Y., Matsushita, S.
- Journal Title
  
  Journal of Clinical Pathology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Positional effect of amino acid replacement on peptide antigens for the increased IFN-γ production from CD4 T cells.2005
- Author(s)
  Liu, T., Kohsaka, H., Suzuki, M., Takagi, R., Hashimoto, K., Uemura, Y., Ohyama, H., Matsushita, S.
- Journal Title
  
  Allergology International 54(1)
  
  Pages: 117-122
- NAID
  10014468942
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Polymorphism of the 5' flanking region of the IL-12 receptor β2 gene partially detennines the clinical types of leprosy through impaired transcriptional activity.2005
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Clinical Pathology (in press)
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Polymorphism of the 5' flanking region of the IL-12 receptor β2 gene partially determines the clinical types of leprosy through impaired transcriptional activity.2005
- Author(s)
  Hideki Ohyama
- Journal Title
  
  Journal of Clinical Pathology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] HLA-mediated signaling via HLA-peptide-TCR complex determines immune responses of antigen-presenting cells.2004
- Author(s)
  Matsushita, S., Ohyama, H., Kudo, H, Tabata, H., Matsuoka, T.
- Journal Title
  
  Current Topics in Peptide & Protein Research 6
  
  Pages: 1-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Monocytes of distinct clinical types of leprosy are differentially activated by cross-linking class II HLA molecules to secrete IL-12.2004
- Author(s)
  Ohyama, H., Kato, N., Takeuchi, K., Soga, Y., Uemura, Y., Nishimura, F., Matsushita, S.
- Journal Title
  
  APMIS 112(4-5)
  
  Pages: 271-274
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Monocytes of distinct clinical types of leprosy are differentially activated by crosslinking class II HLA molecules to secrete IL-12.2004
- Author(s)
  Hideki Ohyama
- Journal Title
  
  APMIS 112・4-5
  
  Pages: 271-274
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Tumor necrosis factor-alpha gene(TNF-α) -1031/-863,-857 single nucleotide polymorphisms(SNPs) are associated with severe adult periodontitis in Japanese.2003
- Author(s)
  Soga Y, Nishimura F, Ohyama H, Maeda H, Takashiba S, Murayama Y.
- Journal Title
  
  Journal of Clinical Pathology 30(6)
  
  Pages: 524-531
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] Ligation of IFN-γ-induced HLA-DR molecules on fibroblasts induces RANTES expression via c-Jun N-terminal kinase (JNK) pathway.2003
- Author(s)
  Meguro M, Nishimura F, Ohyama H, Takashiba S, Murayama Y, Matsushita S.
- Journal Title
  
  Cytokine 22(5)
  
  Pages: 107-115
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Journal Article] 歯周病医療から健康科学への貢献とその展望-生物学の立場から・その2-2003
- Author(s)
  大山秀樹
- Journal Title
  
  ザ・クインテッセンス 22・5
  
  Pages: 199-203
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592199
[Patent] IFN-γ低産生関連IL-12R β2遺伝子プロモーター領域の多型とその検出方法2010
- Inventor(s)
  緒方是嗣, 山本卓志, 松下祥, 大山秀樹
- Industrial Property Rights Holder
  緒方是嗣, 山本卓志, 松下祥, 大山秀樹
- Acquisition Date
  2010-12-24
- Data Source
  KAKENHI-PROJECT-20592443
[Patent] IFN-・低産生関連IL-12Rβ2遺伝子プロモーター領域の多型とその検出方法2010
- Inventor(s)
  緒方是嗣,山本卓志,松下祥,大山秀樹
- Industrial Property Rights Holder
  株式会社島津製作所,松下祥,大山秀樹
- Acquisition Date
  2010-12-24
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] IL-22/TNF-αの単独および共刺激によって誘導されるヒト歯根膜由来細胞の生物学的活性2013
- Author(s)
  川辺睦記,浦出雅裕,大山秀樹
- Organizer
  第67回日本口腔科学会学術集会
- Place of Presentation
  栃木県総合文化センター(栃木県)
- Year and Date
  2013-05-23
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] 低酸素による細胞表面MICAの糖鎖修飾の低下2013
- Author(s)
  山田直子、山根木康嗣、大山秀樹、寺田信行、中正恵二
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] ステロイドを長期服用する関節リウマチ患者に発症した肺クリプトコックス症の１剖検例2013
- Author(s)
  大山秀樹
- Organizer
  真菌症フォーラム第14回学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] ヒストン脱アセチル化阻害剤を用いた腫瘍血管新生抑制2012
- Author(s)
  山根木康嗣、小林健太、中正恵二、大山秀樹、山田直子、秦正樹、寺田信行
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592247
[Presentation] 骨肉腫細胞における低酸素誘導性の細胞表面MICAの発現低下2012
- Author(s)
  山田直子、山根木康嗣、大山秀樹、中正恵二、秦正樹、寺田信行
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24592247
[Presentation] Th17細胞産生性サイトカインが血管石灰化に及ぼす影響2012
- Author(s)
  大山秀樹
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] Th17細胞産生性サイトカインが血管石灰化に及ぼす影響2012
- Author(s)
  大山秀樹
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2012-04-27
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] 骨肉腫細胞における低酸素誘導性の細胞表面MICAの発現低下2012
- Author(s)
  山田直子、山根木康嗣、大山秀樹、中正恵二、秦正樹、寺田信行
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] 骨肉腫細胞における低酸素誘導性の細胞表面MICAの発現低下2012
- Author(s)
  山田直子、山根木康嗣、大山秀樹、中正恵二、秦正樹、寺田信行
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] Th17細胞産生性サイトカインが血管石灰化に及ぼす影響2012
- Author(s)
  大山秀樹、片岡芙紗、川辺睦記、小越菜保子、山根木康嗣、山田直子、秦正樹、中正恵二、寺田信行
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] IL-22がヒト歯根膜由来細胞の石灰化ノジュール形成に及ぼす影響2011
- Author(s)
  大山秀樹，小越菜保子，川辺睦記，安川陽子，安孫子宜光
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] IL‐22存在下においてヒト歯根膜由来細胞が発現する遺伝子の網羅的解析2011
- Author(s)
  川辺睦記,大山秀樹,安川陽子,小越菜保子,安孫子宜光
- Organizer
  第54回日本歯周病学会春季学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] IL12BR2転写活性の個体差におけるAP-1ファミリー転写因子の関与．2011
- Author(s)
  大山秀樹
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  パシィフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] pigenetic drugによるヒト骨肉腫細胞の抗腫瘍免疫細胞に対する感受性亢進2011
- Author(s)
  山根木康嗣, 小林健太, 大山秀樹, 秦正樹, 山田直子, 中正恵二, 寺田信行
- Organizer
  日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] IL-22がヒト歯根膜由来細胞の石灰化ノジュール形成に及ぼす影響2011
- Author(s)
  大山秀樹
- Organizer
  第54回日本歯周病学会春季学術大会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] 骨肉腫に対するIL-18とイホマイドの併用療法の可能性2011
- Author(s)
  山田直子、秦正樹、山根木康嗣、大山秀樹、中正恵二、麩谷博之、岡村春樹、寺田信行
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] 骨肉腫に対するIL-18とイホマイドの併用療法の可能性2011
- Author(s)
  山田直子、秦正樹、山根木康嗣、大山秀樹、中正恵二、麩谷博之、岡村春樹、寺田信行
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] IL-22存在下においてヒト歯根膜由来細胞が発現する遺伝子の網羅的解析2011
- Author(s)
  川辺睦記，大山秀樹，安川陽子，小越菜保子，安孫子宜光
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23593077
[Presentation] IL-22がヒト歯根膜由来細胞の石灰化ノジュール形成に及ぼす影響2011
- Author(s)
  大山秀樹
- Organizer
  第54回日本歯周病学会春季学術大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23593076
[Presentation] IL12RB2転写活性の個体差におけるAP-1ファミリー転写因子の関与2011
- Author(s)
  大山秀樹、小越菜保子、山根木康嗣、山田直子、秦正樹、片岡芙紗、中正恵二、寺田信行
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] Epigenetic drugによるヒト骨肉腫細胞の抗腫瘍免疫細胞に対する感受性亢進2011
- Author(s)
  山根木康嗣、小林健太、大山秀樹、秦正樹、山田直子、中正恵二、寺田信行
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590480
[Presentation] 短期集中的な口腔衛生管理により重度白血病性歯肉炎の軽快を見た急性骨髄性白血病患者の1症例2010
- Author(s)
  蔵下舞,大山秀樹,木崎久美子,橋谷進
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] T細胞応答性から捉えた歯周病に対する疾患感受性の個体差に関する免疫遺伝学的研究(学会学術賞受賞記念講演)2010
- Author(s)
  大山秀樹
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] IL-22がヒト歯根膜細胞の石灰化ノジュール形成に及ぼす影響2010
- Author(s)
  大山秀樹,小越菜保子,西岡稔浩,山根木康嗣,山田直子,秦正樹,中正恵二,寺田信行
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2010-04-29
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 学会学術賞受賞記念講演:T細胞応答性から捉えた歯周病に対する疾患感受性の個体差に関する免疫遺伝学的研究2010
- Author(s)
  大山秀樹
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 造血幹細胞移植の予後に関連する歯周疾患因子について2010
- Author(s)
  橋谷進,木崎久美子,蔵下舞,大山秀樹
- Organizer
  第53回春季日本歯周病学会学術大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] ヒストン脱アセチル化阻害剤とDNAメチル化阻害剤の併用による抗腫瘍免疫細胞に対する感受性増加2010
- Author(s)
  山根木康嗣、小林健太、大山秀樹、小越菜保子、西岡稔浩、秦正樹、山田直子、中正恵二、寺田信行
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] DNAメチル化阻害剤とヒストン脱アセチル化阻害剤の併用によるヒト骨肉腫細胞の抗腫瘍免疫細胞抵抗性の減弱2009
- Author(s)
  山根順子,山根木康嗣,大山秀樹,小越菜保子,秦正樹,山田直子,中正恵二,寺田信行
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] 骨肉腫に対するIL-18とイホマイドの併用療法の可能性(Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model)2009
- Author(s)
  山田直子、大山秀樹、山根木康嗣、小越菜保子、秦正樹、中正恵二、岡村春樹、寺田信行
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] Cooperative Antitumor Effects by Combined Administration α-Galactosylceramide and Interleukin-18 on Pulmonary Metastasis of Malignant Melanoma Cells.2009
- Author(s)
  Naoko Yamada, Shoji Nishio, Hideki Ohyama, Koji Yamanegi, Keiji Nakasho, Haruki Okamura, Nobuyuki Terada
- Organizer
  The 11th Mutagenesis and Experimental Pathology Society of Australia
- Place of Presentation
  Sydney, NSW, Australia
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] 歯周病病態形成におけるIL-23/IL-17産生系の関与2009
- Author(s)
  大山秀樹,小越菜保子,西村英紀,山根木康嗣,橋谷進,木崎久美子
- Organizer
  第52回春季日本歯周病学会学術大会
- Place of Presentation
  岡山
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] IL12RB2転写制御領域の多型はT細胞とNK細胞との間で異なった影響を及ぼす2009
- Author(s)
  大山秀樹,小越菜保子,西岡稔浩,中正恵二,山根木康嗣,山田直子,秦正樹,山根純子,寺田信行
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 血球貪食症候群が原因と考えられる高度肝壊死の2剖検例2009
- Author(s)
  中正恵二, 山根木康嗣, 大山秀樹, 西岡稔浩, 平野博嗣, 沖村明, 山田直子, 秦正樹, 山根順子, 小越菜保子, 寺田信行
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] IL12RB2転写制御領域の多型はT細胞とNK細胞との間で異なった影響を及ぼす2009
- Author(s)
  大山秀樹,小越菜保子,西岡稔浩,中正恵二,山根木康嗣,山田直子,秦正樹,山根順子,寺田信行
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] ヒストン脱アセチル化阻害剤によるヒト骨肉腫細胞の免疫療法抵抗性の減弱2009
- Author(s)
  山根木康嗣,山根順子,大山秀樹,小越菜保子,秦正樹,山田直子,中正恵二,寺田信行
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] IL12RB2転写制御領域の多型はT細胞とNK細胞との間で異なった影響を及ぼす2009
- Author(s)
  大山秀樹
- Organizer
  第96回日本病理学会総会.
- Place of Presentation
  京都
- Year and Date
  2009-05-03
- Data Source
  KAKENHI-PROJECT-20599020
[Presentation] 当院妊婦母親教室参加者における歯周病に対する意識調査2009
- Author(s)
  橋谷進,木崎久美子,大山秀樹
- Organizer
  第52回春季日本歯周病学会学術大会
- Place of Presentation
  岡山
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 歯周病細菌感染に起因したと考えられる化膿性肝膿瘍の1剖検例2009
- Author(s)
  大山秀樹
- Organizer
  第129回日本歯科保存学会秋季学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20599020
[Presentation] 歯周病病態形成におけるIL-23/IL-17産生系の関与2009
- Author(s)
  大山秀樹,小越菜保子,西村英紀,山根木康嗣,橋谷進,木崎久美子
- Organizer
  第52回春季日本歯周病学会学術大会
- Place of Presentation
  岡山
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20599020
[Presentation] 産生系の関与2009
- Author(s)
  大山秀樹, 小越菜保子, 西村英紀, 山根木康嗣, 橋谷進, 木崎久美子
- Organizer
  第52回春季日本歯周病学会学術大会
- Place of Presentation
  岡山
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] 歯周病細菌感染に起因したと考えられる化膿性肝膿瘍の1剖検例2009
- Author(s)
  大山秀樹, 野杁由一郎, 小越菜保子, 西村英紀, 恵比須繁之
- Organizer
  第130回日本歯科保存学会2009年度春季学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] 歯周病細菌感染に起因したと考えられる化膿性肝膿瘍の1剖検例2009
- Author(s)
  大山秀樹,野杁由一郎,小越菜保子,西村英紀,恵比須繁之
- Organizer
  第130回日本歯科保存学会2009年度春季学術大会
- Place of Presentation
  札幌
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 肝内限局型原発性硬化性胆管炎の2切除例2008
- Author(s)
  中正恵二, 平野博嗣, 沖村明, 柴垣昌史, 大山秀樹, 山根木康嗣, 山田直子, 秦正樹, 山根順子, 寺田信行, 覚野綾子, 安井智明, 山中若樹
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] ヒト骨肉腫細胞の免疫療法抵抗性に対するhistone deacetylase inhibitorの効果2008
- Author(s)
  山根木康嗣、山根順子、秦正樹、大山秀樹、山田直子、小越菜保子、中正恵二、寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] 全身病理における歯周病医学の位置づけ2008
- Author(s)
  大山秀樹
- Organizer
  東北大学歯学部同窓会サマーセミナー
- Place of Presentation
  大阪
- Year and Date
  2008-09-07
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 歯周病-感染性疾患として全身に及ぼす影響-2008
- Author(s)
  大山秀樹
- Organizer
  第42回日本病理学会近畿支部学術集会
- Place of Presentation
  西宮
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] 歯周病細菌感染に起因したと考えられる化膿性肝膿瘍の1剖検例2008
- Author(s)
  鷲尾輝明,大山秀樹,中正恵二,山根木康嗣,久原彩子,小越菜保子,山田直子,秦正樹,山根純子,野杁由一郎,恵比須繁之,寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] クラスII HLA分子を介した刺激を受けた歯肉線維芽細胞によるTh細胞応答性の制御2008
- Author(s)
  大山秀樹,小越菜保子,目黒道生,吉澤さゆり,岡田祐佳,西村英紀
- Organizer
  第129回日本歯科保存学会秋季学術大会
- Place of Presentation
  富山
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] クラスII HLA分子を介した刺激を受けた歯肉線維芽細胞によるTh細胞応答性の制御2008
- Author(s)
  大山秀樹,小越菜保子,目黒道生,吉澤さゆり,岡田祐佳,西村英紀
- Organizer
  第129回日本歯科保存学会秋季学術大会
- Place of Presentation
  富山
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-20599020
[Presentation] ヒト骨肉腫細胞の免疫療法抵抗性に対するhistone deacetylase inhibitorの効果2008
- Author(s)
  山根木康嗣,山根純子,秦正樹,大山秀樹,山田直子,小越菜保子,中正恵二,寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] IL12RB2転写制御領域の遺伝子多型が侵襲性歯周炎に対する疾患感受性の個体差に及ぼす影響2008
- Author(s)
  大山秀樹,畑中加珠,小越菜保子,西村英紀,曽我賢彦,中正恵二,山根木康嗣,山田直子,秦正樹,山根純子,高柴正悟,寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 歯周病-感染性疾患として全身に及ぼす影響-2008
- Author(s)
  大山秀樹
- Organizer
  第42回日本病理学会近畿支部学術集会
- Place of Presentation
  西宮
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] 脾臓に移植された肝細胞の胆管上皮細胞への分化2008
- Author(s)
  秦正樹,渡邉博文,大山秀樹,山田直子,山根木康嗣,小越菜保子,山根純子,中正恵二,寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20592443
[Presentation] IL12RB2転写制御領域の遺伝子多型が侵襲性歯周炎に対する疾患感受性の個体差に及ぼす影響2008
- Author(s)
  大山秀樹、畑中加珠、小越菜保子、西村英紀、曽我賢彦、中正恵二、山根木康嗣、山田直子、秦正樹、山根順子、高柴正悟、寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20590414
[Presentation] 臓に移植された肝細胞の胆管上皮細胞への分化2008
- Author(s)
  秦正樹, 渡邊博文, 大山秀樹, 山田直子, 山根木康嗣, 小越菜保子, 山根順子, 中正恵二, 寺田信行
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] 歯周炎感受性に関する免疫遺伝学的アプローチーハンセン病を疾患モデルとして捉えた研究-2007
- Author(s)
  大山秀樹
- Organizer
  日本口腔病理学会総会・学術大会
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] クラスII HLA分子を介した刺激を受けた歯肉線維芽細胞によるTh1/Th2応答性の制御2007
- Author(s)
  大山秀樹
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] PGE2 produced from fibroblasts via HLA-II stimulation regulates Thl/Th2 polarization.2007
- Author(s)
  Hideki Ohyama
- Organizer
  85th International Association for Dental Research.
- Place of Presentation
  New Orleans(USA)
- Year and Date
  2007-03-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] 歯周炎感受性に関する免疫遺伝学的アプローチ2007
- Author(s)
  大山秀樹
- Organizer
  日本口腔病理学会総会・学術大会
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] PGE2 produced from fibroblasts via HLA-II stimulation regulates Th1/Th2 polarization2007
- Author(s)
  Hideki Ohyama
- Organizer
  85th International Association for Dental Research
- Place of Presentation
  New Orleans(USA)
- Year and Date
  2007-03-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] 歯周炎感受性に関する免疫遺伝学的アプローチ-ハンセン病を疾患モデルとして捉えた研究-2007
- Author(s)
  大山秀樹
- Organizer
  第18回日本口腔病理学会総会・学術大会
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19592399
[Presentation] 肝炎症性偽腫瘍の1例2006
- Author(s)
  大山秀樹
- Organizer
  第95回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2006-05-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] 歯周組織におけるクラスII HLA分子が関わる免疫防御機構2006
- Author(s)
  大山秀樹
- Organizer
  大阪大学大学院歯学研究科21世紀COEシンポジウム2006「歯周組織のバイオロジー, 基礎から臨床まで」
- Place of Presentation
  大阪
- Year and Date
  2006-10-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] The effects of 5'flanking region gene polymorphism of IL12RB2 on NK cell activity.2006
- Author(s)
  Hideki Ohyama
- Organizer
  Forty-first Tuberculosis and Leprosy Research Conference, US-Japan Cooperative Medical Science Program.
- Place of Presentation
  Kagoshima(Japan)
- Year and Date
  2006-07-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] 早期発症型歯周炎患者におけるP.gingivalis由来53kDa外膜蛋白に対するT細胞応答性2006
- Author(s)
  大山秀樹
- Organizer
  第95回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2006-05-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] The effects of 5'flanking region gene polymorphism of IL12RB2 on NK cell activity2006
- Author(s)
  Hideki Ohyama
- Organizer
  Forty-first Tuberculosis and Leprosy Research Conference, US-Japan Cooperative Medical Science Program
- Place of Presentation
  Kagoshima(Japan)
- Year and Date
  2006-07-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592274
[Presentation] 低酸素による細胞表面MICAの糖鎖修飾の低下
- Author(s)
  山田直子, 山根木康嗣, 大山秀樹, 寺田信行, 中正恵二
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24592247
[Presentation] IL-22／TNF-αの単独および共刺激によって誘導されるヒト歯根膜由来細胞の生物学的活性
- Author(s)
  川邊睦記，浦出雅裕，大山秀樹
- Organizer
  第67回 NPO法人日本口腔科学会学術集会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-23593076

1. YAMADA Naoko (10319858)

# of Collaborated Projects: 10 results

# of Collaborated Products: 66 results
2. YAMANEGI Koji (00434944)

# of Collaborated Projects: 10 results

# of Collaborated Products: 68 results
3. NAKASHO Keiji (00217712)

# of Collaborated Projects: 9 results

# of Collaborated Products: 65 results
4. TERADA Nobuyuki (50150339)

# of Collaborated Projects: 8 results

# of Collaborated Products: 66 results
5. NISHIMURA FUSANORI (80208222)

# of Collaborated Projects: 7 results

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6. KOGOE Nahoko (60509115)

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# of Collaborated Products: 12 results
7. MURAYAMA Yoji (50029972)

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9. TAKASHIBA Shogo (50226768)

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10. URADE Masahiro (70104883)

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11. YAMANO Tomoki (00599318)

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13. MAEDA Hiroshi (00274001)

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19. TOMITA Naohiro (00252643)

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20. HATA Masaki (10446057)

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21. TANIMOTO Ichiro (00280686)

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22. ARAI Hideo (70222718)

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23. MINESHIBA Fumi (90346461)

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24. NARUISHI Koji (00346446)

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25. MATSUSHITA Sho (50167649)

# of Collaborated Projects: 1 results

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26. UEMURA Yasushi (40364781)

# of Collaborated Projects: 1 results

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27. HASHITANI Susumu (00330449)

# of Collaborated Projects: 1 results

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28. 苔口進 (10144776)

# of Collaborated Projects: 1 results

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29. 栗原英見 (40161765)

# of Collaborated Projects: 1 results

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30. 河野隆幸 (80284074)

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31. 浅野知一郎 (70242063)

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33. 中山真彰 (10579105)

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34. 木村吉宏 (00351388)

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35. 中島世市郎 (10720691)

# of Collaborated Projects: 1 results

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36. 大森実知 (60803137)

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37. FUTANI Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
38. FUKUNAGA Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. 西浦弘志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 通山由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 畑中加珠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 廣瀬宗孝

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# of Collaborated Products: 1 results

OHYAMA Hideki 大山 秀樹

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Potential role of IL-1 family cytokines in periodontal diseasesPrincipal Investigator

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The effect of IL-22 on biological activity of periodontal ligament cellsPrincipal Investigator

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A study on the effects of products from non-hemocyte cells activated by crosslinking HLA-II molecules on Th-cell differentiation in periodontal diseasesPrincipal Investigator

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OHYAMA Hideki 大山秀樹