MYOKAI Fumio 明貝文夫

… Alternative Names

Researcher Number	50263588
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2003 – 2005: Okayama University, University Hospital of Medicine and Dentistry, Assistant Professor, 医学部・歯学部附属病院, 講師 2001 – 2002: Okayama University Graduate School of Medicine and Dentistry, Department of Pathophysiology - Periodontal Science, Instractor, 大学院・医歯学総合研究科, 助手 1998 – 2000: Okayama Univ.Dental Sch., Assistant, 歯学部, 助手 1994: Okayama Univ., Dent.Sch., Assistant Prof., 歯学部, 助手
Review Section/Research Field	Principal Investigator Periodontal dentistry / Conservative dentistry / Periodontal dentistry Except Principal Investigator Periodontal dentistry / Conservative dentistry
Keywords	Principal Investigator 機械的刺激 / LITAF / 骨再生 / 転写制御 / Cbfa1 / 機械的剌激 / 遺伝子発現 / Bone Regeneration / root resorption / ウエスタンブロット … More Except Principal Investigator 局所遺伝子導入 / Phosphorylation / vascular endothelial growth factor / 抗菌ペプチド / CD11 / Leukotoxin / 組織再生 / 歯周病 / Cyclic AMP / Protein kinase C / CD18 / Local Gene Delivery / anti-angiogenic effect / DNA合成 / IL-6 / 遺伝子発現 / Regulation of Gene Transcription / コラーゲン合成 / PBSCT / 抗炎症療法 / ケミカルトランスフェクション法 / 遺伝子多型 / 薬物代謝酵素 / Concentration(C) / 表現型 / 口腔細菌 / アルカリホスフォターゼ活性 / 歯周炎 / cathepsin-L / セリンスレオニンキナーゼレセプター発現 / トランスフォーミング成長因子(TGF-β) / FMLP / compromised host / Porphyromonas gingivalis / マウスモデル / 炎症性サイトカイン / Tissue regeneration / フェニトイン / 生体機能利用 / 白血球数 / Periodontal disease / cAMP / 腫瘍壊死因子 / 細胞障害性 / 唾液(腺) / Anti-inflammatory Therapy / sTNFR1 / ラット唾液腺 / sTNFR2 / 顎下腺 / Ca拮抗剤 / カテプシン / トランスフォーミング成長因子(TGF-β)レセプター / 細菌感染制御 / 遺伝子欠損マウス / 欠損マウス / 可溶性TNF-α受容体 / ヒトβ-defensin-2 / 炎症制御 / 誤嚥性肺炎 / チトクロームP450 / bacterial detection / 好中球 / 歯周組織再生 / 局所的遺伝子療法 / プロテインキナーゼC / Actinobacillus actinomycetemcomitans / TNF-α / 細菌検査 / 歯学 / カテプシン-L / TGF-beta receptor / 口腔管理 / 局所炎症と全身 / periodontal desease / 免疫抑制剤 / ライソゾーム酵素 / Antimicrobial peptide / 易感染性宿主 / 若年性歯周炎 / 遺伝子治療 / Transforming growth factor-beta (TGF-beta) / β-ガラクトシダーゼ / A.actinomycetemcomitans / 薬物代謝 / Dentistry / Regulation of cell function / drug metabolizing enzyme / 活性型ビタミンD_3レセプター / 歯髄 / oral infection control / Reparative dentin / CYP2C9 / 血管新生抑制作用 / サイクロスポリン / Gene transcription / Periodontal tissue regeneration / 上皮(細胞) / drug-induced gingival overgrowth / 歯根膜線維芽細胞 / 歯周疾患 / LFA-1 / IL-1β / 唾液 / Oral microbe / lysosomal enzymes / 機械的外力 / Periodontal ligament fibroblast / ニフェジピン / Intracellular calucium ion / 抗てんかん薬 / I-cell病 / Dose(D)ratio / leukocyte / 末梢血幹細胞移植 / 走化能 / deficient mice / Local gene therapy / 薬物性歯肉増殖症 / Intercellular calcium ion / 遺伝子転写制御 / TNF / single nucleotide polymorphism / Dental pulp / 細胞機能制御 / 局所遺伝子治療 / in situハイブリダイゼーション / トランスフォーミング成長因子 / 修復象牙質 / TGF-β / Regulation of inflammation / CYP2C19 / 遺伝子サブトラクション / Utilization of host defense / Periodontal Disease Less

歯周靭帯細胞における機械的ストレス応答性遺伝子のグルーピングと転写機構Principal Investigator
- Principal Investigator
  
  明貝文夫
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
歯周病原性細菌によって起こる誤嚥性肺炎の分子免疫学的病態の研究
- Principal Investigator
  
  高柴正悟
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Gene Therapy for Periodontal Diseases -Regulation of host response by local gene delivery-
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Role of a novel transcription factor for TNF-α, LITAF, on the pathogenesis of periodontitisPrincipal Investigator
- Principal Investigator
  
  MYOKAI Fumio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Study on the pathogenesis of drug-induced gingival overgrowth -A study with deficient mice
- Principal Investigator
  
  NISHIMURA Fusanori
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study for oral infectious control during peripheral blood stem cell transplantation
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Periodontal Treatment by Regulation of Novel TNF-α Transcription Factor in Monocytes
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Factor for induction of root resorptionPrincipal Investigator
- Principal Investigator
  
  MYOKAI Fumio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  OKAYAMA UNIVERSITY
上皮由来抗菌ペプチドの利用による歯周病原性細菌の感染予防にむけて
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study for preservation of dentin using local gene deliveryof dentin-specific genes
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Studies on bone regeneration by application of osteoblast differentiation marker, Cbfal, gene productsPrincipal Investigator
- Principal Investigator
  
  MYOKAI Fumio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study on the control of periodontal ligament fibroblast functions by transforming growth factor
- Principal Investigator
  
  ARAI Hideo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Studies on signal transduction of neutrophils from early-onset periodonititis patients
- Principal Investigator
  
  KURIHARA Hidemi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University

All 2005 2004

All Journal Article

[Journal Article] Mechanical Stress-induced Gene Expression Essential for HPLF Growth2005
- Author(s)
  YAMASHIRO, K., MYOKAI, F., HIRATSUKA, K., SENOO, K., NISHIMURA, F., ABIKO, Y., TAKASHIBA, S.
- Journal Title
  
  Journal of Dental Research Abstract(In press)
- Data Source
  KAKENHI-PROJECT-16659579
[Journal Article] 機械的刺激が培養ヒト歯根膜線維芽細胞に及ぼす遺伝子発現変化のマイクロアレイ解析2004
- Author(s)
  山城圭介, 平塚浩一, 明貝文夫, 妹尾京子, 高柴正悟, 安孫子宜光
- Journal Title
  
  日本歯周病学会会誌 46(春季特別号)
  
  Pages: 124-124
- Data Source
  KAKENHI-PROJECT-16659579

1. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 10 results

# of Collaborated Products: 2 results
2. NISHIMURA Fusanori (80208222)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
3. MAEDA Hiroshi (00274001)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. ARAI Hideo (70222718)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. MURAYAMA Yoji (50029972)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. KOHNO Takayuki (80284074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 苔口進 (10144776)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 大山秀樹 (90280685)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KURIHARA Hidemi (40161765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HONGYO Hiroshi (80243476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAGAWA Masatsugu (80243468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISOSHIMA Osamu (90176256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WASHIO Norifumi (40263602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAHASHI Keiso (70243475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANIMOTO Ichiro (00280686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MINESHIBA Fumi (90346461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NARUISHI Koji (00346446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KUBOKI Takuo (00225195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KUBOTA Satoshi (90221936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 宮本学 (40252978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小林芳友 (90234856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 永井淳 (70252989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 滝川雅之 (60243474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MYOKAI Fumio 明貝 文夫

MYOUKAI Fumio 明貝 文夫

Research Projects

Research Products

Co-Researchers

歯周靭帯細胞における機械的ストレス応答性遺伝子のグルーピングと転写機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

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Role of a novel transcription factor for TNF-α, LITAF, on the pathogenesis of periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Factor for induction of root resorptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Studies on bone regeneration by application of osteoblast differentiation marker, Cbfal, gene productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mechanical Stress-induced Gene Expression Essential for HPLF Growth2005

Author(s)

Journal Title

Data Source

[Journal Article] 機械的刺激が培養ヒト歯根膜線維芽細胞に及ぼす遺伝子発現変化のマイクロアレイ解析2004

Author(s)

MYOKAI Fumio 明貝文夫

MYOUKAI Fumio 明貝文夫