MYOKAI Fumio 明貝文夫

… Alternative Names

Researcher Number	50263588
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2003 – 2005: Okayama University, University Hospital of Medicine and Dentistry, Assistant Professor, 医学部・歯学部附属病院, 講師 2001 – 2002: Okayama University Graduate School of Medicine and Dentistry, Department of Pathophysiology - Periodontal Science, Instractor, 大学院・医歯学総合研究科, 助手 1998 – 2000: Okayama Univ.Dental Sch., Assistant, 歯学部, 助手 1994: Okayama Univ., Dent.Sch., Assistant Prof., 歯学部, 助手
Review Section/Research Field	Principal Investigator Periodontal dentistry / Periodontal dentistry / Conservative dentistry Except Principal Investigator Periodontal dentistry / Conservative dentistry
Keywords	Principal Investigator 機械的刺激 / LITAF / ヒト歯根膜線維芽細胞 / マイクロアレイ / 骨再生 / Cbfa1 / 遺伝子発現 / in situ hybridization / Bone Regeneration / Cbfal … More Except Principal Investigator 局所遺伝子導入 / 歯周病 / 抗菌ペプチド / Protein kinase C / Cyclic AMP / CD18 / CD11 / Phosphorylation / Leukotoxin / 組織再生 / Local Gene Delivery / vascular endothelial growth factor / 細菌感染制御 / 上皮(細胞) / 唾液(腺) / TNF-α / sTNFR1 / sTNFR2 / IL-1β / IL-6 / 誤嚥性肺炎 / Porphyromonas gingivalis / マウスモデル / 炎症性サイトカイン / 可溶性TNF-α受容体 / 局所炎症と全身 / Intercellular calcium ion / Actinobacillus actinomycetemcomitans / 若年性歯周炎 / 好中球 / 走化能 / プロテインキナーゼC / LFA-1 / FMLP / cAMP / Intracellular calucium ion / A.actinomycetemcomitans / 歯根膜線維芽細胞 / トランスフォーミング成長因子 / トランスフォーミング成長因子(TGF-β)レセプター / 歯周組織再生 / 細胞機能制御 / TGF-β / セリンスレオニンキナーゼレセプター発現 / 機械的外力 / in situハイブリダイゼーション / トランスフォーミング成長因子(TGF-β) / DNA合成 / コラーゲン合成 / アルカリホスフォターゼ活性 / 活性型ビタミンD_3レセプター / Periodontal ligament fibroblast / Transforming growth factor-beta (TGF-beta) / TGF-beta receptor / Periodontal tissue regeneration / Regulation of cell function / 歯髄 / 修復象牙質 / 遺伝子発現 / 遺伝子サブトラクション / Dental pulp / Reparative dentin / Gene transcription / Tissue regeneration / 歯周炎 / 腫瘍壊死因子 / 遺伝子転写制御 / 抗炎症療法 / Periodontal disease / TNF / Regulation of Gene Transcription / Anti-inflammatory Therapy / 薬物性歯肉増殖症 / ライソゾーム酵素 / カテプシン-L / 遺伝子欠損マウス / 血管新生抑制作用 / 薬物代謝酵素 / 遺伝子多型 / 薬物代謝 / フェニトイン / チトクロームP450 / CYP2C9 / CYP2C19 / Concentration(C) / Dose(D)ratio / Ca拮抗剤 / 抗てんかん薬 / 免疫抑制剤 / カテプシン / 欠損マウス / 表現型 / ニフェジピン / サイクロスポリン / I-cell病 / drug-induced gingival overgrowth / lysosomal enzymes / cathepsin-L / deficient mice / anti-angiogenic effect / drug metabolizing enzyme / single nucleotide polymorphism / 末梢血幹細胞移植 / 易感染性宿主 / 口腔管理 / 歯周疾患 / 細菌検査 / 白血球数 / PBSCT / compromised host / oral infection control / periodontal desease / bacterial detection / leukocyte / 歯学 / 局所遺伝子治療 / 生体機能利用 / 口腔細菌 / 炎症制御 / 遺伝子治療 / ヒトβ-defensin-2 / 顎下腺 / 唾液 / 局所的遺伝子療法 / ラット唾液腺 / β-ガラクトシダーゼ / 細胞障害性 / ケミカルトランスフェクション法 / Dentistry / Periodontal Disease / Local gene therapy / Utilization of host defense / Oral microbe / Antimicrobial peptide / Regulation of inflammation Less

歯周靭帯細胞における機械的ストレス応答性遺伝子のグルーピングと転写機構Principal Investigator
- Principal Investigator
  
  明貝文夫
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
歯周病原性細菌によって起こる誤嚥性肺炎の分子免疫学的病態の研究
- Principal Investigator
  
  高柴正悟
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Gene Therapy for Periodontal Diseases -Regulation of host response by local gene delivery-
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Role of a novel transcription factor for TNF-α, LITAF, on the pathogenesis of periodontitisPrincipal Investigator
- Principal Investigator
  
  MYOKAI Fumio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Study on the pathogenesis of drug-induced gingival overgrowth -A study with deficient mice
- Principal Investigator
  
  NISHIMURA Fusanori
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study for oral infectious control during peripheral blood stem cell transplantation
- Principal Investigator
  
  TANIMOTO Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Periodontal Treatment by Regulation of Novel TNF-α Transcription Factor in Monocytes
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Factor for induction of root resorptionPrincipal Investigator
- Principal Investigator
  
  MYOKAI Fumio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  OKAYAMA UNIVERSITY
上皮由来抗菌ペプチドの利用による歯周病原性細菌の感染予防にむけて
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study for preservation of dentin using local gene deliveryof dentin-specific genes
- Principal Investigator
  
  TAKASHIBA Shogo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  OKAYAMA UNIVERSITY
Studies on bone regeneration by application of osteoblast differentiation marker, Cbfal, gene productsPrincipal Investigator
- Principal Investigator
  
  MYOKAI Fumio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Okayama University
Study on the control of periodontal ligament fibroblast functions by transforming growth factor
- Principal Investigator
  
  ARAI Hideo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University
Studies on signal transduction of neutrophils from early-onset periodonititis patients
- Principal Investigator
  
  KURIHARA Hidemi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Conservative dentistry
- Research Institution
  Okayama University

All 2005 2004

All Journal Article

[Journal Article] Mechanical Stress-induced Gene Expression Essential for HPLF Growth2005
- Author(s)
  YAMASHIRO, K., MYOKAI, F., HIRATSUKA, K., SENOO, K., NISHIMURA, F., ABIKO, Y., TAKASHIBA, S.
- Journal Title
  
  Journal of Dental Research Abstract(In press)
- Data Source
  KAKENHI-PROJECT-16659579
[Journal Article] 機械的刺激が培養ヒト歯根膜線維芽細胞に及ぼす遺伝子発現変化のマイクロアレイ解析2004
- Author(s)
  山城圭介, 平塚浩一, 明貝文夫, 妹尾京子, 高柴正悟, 安孫子宜光
- Journal Title
  
  日本歯周病学会会誌 46(春季特別号)
  
  Pages: 124-124
- NAID
  10012896011
- Data Source
  KAKENHI-PROJECT-16659579

1. TAKASHIBA Shogo (50226768)

# of Collaborated Projects: 10 results

# of Collaborated Products: 2 results
2. NISHIMURA Fusanori (80208222)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
3. MAEDA Hiroshi (00274001)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. ARAI Hideo (70222718)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. MURAYAMA Yoji (50029972)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. KOHNO Takayuki (80284074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 苔口進 (10144776)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 大山秀樹 (90280685)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KURIHARA Hidemi (40161765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HONGYO Hiroshi (80243476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAGAWA Masatsugu (80243468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISOSHIMA Osamu (90176256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. WASHIO Norifumi (40263602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAHASHI Keiso (70243475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANIMOTO Ichiro (00280686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MINESHIBA Fumi (90346461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NARUISHI Koji (00346446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KUBOKI Takuo (00225195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KUBOTA Satoshi (90221936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 宮本学 (40252978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小林芳友 (90234856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 永井淳 (70252989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 滝川雅之 (60243474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MYOKAI Fumio 明貝 文夫

MYOUKAI Fumio 明貝 文夫

Research Projects

Research Products

Co-Researchers

歯周靭帯細胞における機械的ストレス応答性遺伝子のグルーピングと転写機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

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Role of a novel transcription factor for TNF-α, LITAF, on the pathogenesis of periodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

Project Period (FY)

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Research Institution

Factor for induction of root resorptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Studies on bone regeneration by application of osteoblast differentiation marker, Cbfal, gene productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mechanical Stress-induced Gene Expression Essential for HPLF Growth2005

Author(s)

Journal Title

Data Source

[Journal Article] 機械的刺激が培養ヒト歯根膜線維芽細胞に及ぼす遺伝子発現変化のマイクロアレイ解析2004

Author(s)

MYOKAI Fumio 明貝文夫

MYOUKAI Fumio 明貝文夫