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SUGIHARA Tsuneki
杉原 平樹
Connect your ORCID iD
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Researcher Number
20002157
Other IDs
Affiliation (based on the past Project Information)
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2004: 北海道大学, 病院・教授
2004: 北海道大学, 病院, 教授
2003: Hokkaido Univ., Hospital, Prof, 医学部・歯学部附属病院, 教授
2003: Hokkaido Univ., Hospital, Prof., 教授
2000 – 2002: Hokkaido Univ.Grad.School of Med., chief proffesor, 大学院・医学研究科, 教授
1998 – 1999: 北海道大学, 医学部, 教授
1995: Professor in Plastic and Reconstructive Surgery, Hokkaido University School of Medicine, 医学部, 教授
Review Section/Research Field
Principal Investigator
Plastic surgery
/
General surgery
/
Plastic surgery
Except Principal Investigator
Plastic surgery
/
Plastic surgery
Keywords
Principal Investigator
悪性黒色腫 / MIF / TGF-β / 表皮角化細胞 / 共培養 / アポトーシス / ゲルソリン / メラノーマ関連抗原 / 微小転移 / センチネルリンパ節
…
More
/ 遺伝子 / リンパ節郭清 / RT-PCR / チロシナーゼ / 胎児創傷治癒 / レーザー / 胎児外科 / 細胞外基質 / ヒアルロン酸 / コラーゲン / 再生 / 瘢痕 / 創傷治癒 / Fetal Wound Healing / Laser / Fetal Surgery / Extracellular Matrix / Hyaluronic Acid / Collagen / Regeneration / Scar / 仮骨延長 / 下顎骨 / 犬 / サイトカイン / 膜性骨下 / 膜性骨化 / ラット / ビーグル犬 / initial gap / distraction osteogenesis / mandible / dog / cytokines / membranous bone / ケロイド由来線維芽細胞 / 遺伝子導入 / 表皮細胞 / malignant melanoma / keloid-derived fibroblast / keratinocyte / coculture / apoptosis / introduction of gene / ケロイド / マクロファージ遊走阻止因子 / リゾフォスファチジン酸 / RNA抑制遺伝子導入 / 線維芽細胞 / LPA / keloid / macrophage migration inhibitory factor (MIF) / lysophosphatidic acid (LPA) / siRNA
…
More
Except Principal Investigator
悪性黒色腫 / siRNA / ホメオボックス遺伝子 / ケロイド / アポトーシス / HOXD3 / 浸潤能 / keloid / SNP / TGF-β1 / PGE_2 / cAMP / HOX / カドヘリン / 転移・浸潤 / 細胞接着因子 / 表皮角化細胞 / 線維芽細胞 / 共培養 / TGF-β / 転移能 / 運動能 / HOX D3 / homeobox gene / melanoma / metastatic activity / invasive activity / motility / 遺伝子導入 / ha-tagベクター / トランスフェクタント / リポフェクション法 / エレクトロポーション法 / ゲルソリン / ゲルソリン短縮体 / ヒト皮膚悪性黒色腫 / マーカー遺伝子 / 導入効率 / ヒト表皮角化細胞 / ヒトメラノサイト系細胞 / transfection / ha-tagged vector / transfectant / lipofection / electroporation / gelsolin / gelsolin truncate / human primary melanoma / アンチセンス / フローサイトメトリー / cDNAマイクロアレイ / malignant melanoma / homeobox genes / antisense / invasion / flow cytometry / cDNA microarray / マクロファージ遊走阻止因子 / トランスジェニックマウス / 創傷治癒 / 細胞外基質 / 細胞増殖 / 細胞周期 / macrophage migration inhibitory factor / transgenic mouse / wound healing / extracellular matrix / cellular proliferation / 唇顎口蓋裂 / Lhx8遺伝子 / ゲノム解析 / TCOF1遺伝子 / Cleft lip and palate / Lhx8 gene / Genome / TCOF1 gene / HOX遺伝子 / 転移 / 色素性母斑 / Malignant Melanoma / HOX gene / Metastasis / Nevus Pigmentosus / マクロファージ遊走阻止因子(MIF) / 遺伝子治療 / MIF / gene therapy
Less
Research Projects
(
15
results)
Research Products
(
1
results)
Co-Researchers
(
14
People)
Project Start Year (Newest)
Project Start Year (Oldest)
A new treatment approach for Malignant Melanoma basing on analysis of expression pattern of homeobox genes
Principal Investigator
YAMAMOTO Yuhei
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
Novel gene therapy of keloid by using siRNA
Principal Investigator
SASAKI Satoru
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
Novel Strategy for Treatment of Keloid ; Application of siRNA and Keratinocyte
Principal Investigator
Principal Investigator
TSUTSUMIDA Arata
, 杉原 平樹
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
遺伝子導入表皮角化細胞を介したケロイド発生制御機構の解明とその臨床応用
Principal Investigator
山本 有平
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Plastic surgery
Research Institution
Hokkaido University
Strategic treatment by means of transduction of gene in Malignant Melanoma
Principal Investigator
Principal Investigator
SUGIHARA Tsuneki
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
メラノーマ関連遺伝子を用いたメラノーマ微小転移検出法の開発
Principal Investigator
Principal Investigator
杉原 平樹
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Plastic surgery
Research Institution
Hokkaido University
悪性黒色腫細胞の転移・浸潤は形態形成遺伝子の発現異常によって始まる
Principal Investigator
HAMADA Junichi
Project Period (FY)
2001
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Plastic surgery
Research Institution
Hokkaido University
Analysis of Master Genes Associated with Invasion and Metastasis by Malignant Melanoma
Principal Investigator
YAMAMOTO Yuhei
,
井川 浩晴
Project Period (FY)
2001 – 2003
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Plastic surgery
Research Institution
Hokkaido University
Analysis of MIF function in wound healing using transgenic mouse
Principal Investigator
SASAKI Satoru
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
Genomic Analysis of Non Syndromic Cleft Lip with or without Cleft Palete
Principal Investigator
KAWASHIMA Kunihiro
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
皮膚癌に対する新しい治療法の開発-遺伝子治療の可能性を求めて-
Principal Investigator
Principal Investigator
杉原 平樹
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Plastic surgery
Research Institution
Hokkaido University
A study of regeneration of membranous bone - Interaction of Macrophage migration inhibitory factor with other cytokines -
Principal Investigator
Principal Investigator
SUGIHARA Tsuneki
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
Heterotopic expression of morphogenetic genes and invasiveness in human melanoma cells
Principal Investigator
IGAWA Hiroharu
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
Gene transfection in human keratinocyte and melanocyte
Principal Investigator
YAMAMOTO Yuhei
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Plastic surgery
Research Institution
HOKKAIDO UNIVERSITY
Healing Characteristics of Laser Irradiation-induced Dermal Wounds in Fetal Mice
Principal Investigator
Principal Investigator
SUGIHARA Tsuneki,
井川 浩晴
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General surgery
Research Institution
Hokkaido University
All
2005
All
Journal Article
[Journal Article] Altered expressions of HOX genes in human cutaneous malignant melanoma
2005
Author(s)
Kazuhiko Maeda, Jun-Ichi Hamada, Yoko Takahashi, Mitsuhiro Tada, Yuhei Yamamoto, Tsuneki Sugihara, Tetsuya Moriuchi
Journal Title
International journal of cancer 114
Pages
: 436-441
Description
「研究成果報告書概要(欧文)」より
Data Source
KAKENHI-PROJECT-16390505
# of Projects (Dsc)
# of Projects (Asc)
1.
YAMAMOTO Yuhei
(70271674)
# of Collaborated Projects:
10 results
# of Collaborated Products:
1 results
2.
IGAWA Hiroharu H
(10232159)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
3.
HAMADA Junichi
(50192703)
# of Collaborated Projects:
5 results
# of Collaborated Products:
1 results
4.
TSUTSUMIDA Arata
(00374489)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
MORIUCHI Tetsuya
(20174394)
# of Collaborated Projects:
4 results
# of Collaborated Products:
1 results
6.
SASAKI Satoru
(40301907)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
KAWASHIMA Kunihiro
(30281801)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
NISHIHIRA Jun
(30189302)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
FURUKAWA Hiroshi
(00399924)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
OYAMA Akihiko
(70374486)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
SEKIDO Mitsuru
(40372255)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
YOKOYAMA Toichiro
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
大久保 佳子
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
SAKIYAMA Yukio
(80133734)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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