NISHIHIRA Jyun 西平順

… Alternative Names

Researcher Number	30189302
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Affiliation (Current)	2022: 北海道情報大学, 医療情報学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2021: 北海道情報大学, 医療情報学部, 教授 2013: 北海道情報大学, 公私立大学の部局等, 教授 2013: 北海道情報大学, 医療情報学科, 教授 2011 – 2012: 北海道情報大学, 経営情報学部, 教授 2000 – 2004: 北海道大学, 大学院・医学研究科, 助教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Pathological medical chemistry / Immunology / Immunology Except Principal Investigator Respiratory organ internal medicine / Biophysics / Orthopaedic surgery / Plastic surgery / Anesthesiology/Resuscitation studies / Applied health science … More
Keywords	Principal Investigator MIF / マクロファージ / エンドトキシンショック / サイトカイン / macrophage migration inhibitory factor / 血管新生 / 遺伝子改変動物 / グルタチオン / macrophage / endotoxin schock … More Except Principal Investigator MIF / マクロファージ遊走阻止因子 / macrophage migration inhibitory factor / ARDS / マクロファージ / Macrophage / 赤血球膜 / 膜骨格 / 変形能 / グリコフォリン / エンドトキシン / 肺傷害 / 好中球 / アトピー / イノシトールリン脂質 / MAD / Se-Met / 細胞増殖 / H.pylori / サイトカイン / 線維芽細胞 / TNF-α / IL-6 / PGE_2 / トランスジェニックマウス / siRNA / 4.1蛋白質 / 植物凝集素 / イノシト-ル燐脂質 / 時間分解顕微蛍光法 / ピコ秒パルスレ-ザ- / ヘキサゴナル相 / ジアシルグリセロ-ル / リポソ-ム / 蛍光寿命 / 肺損傷 / MIP-2 / 肺胞マクロファージ / 期間支肺胞洗浄 / 気管支喘息 / COPD / 好酸球 / 敗血症 / ショック / 若年日本人女性 / やせ型体型 / 健康障害 / 若年女性 / 体型 / 体組成 / 動脈硬化因子 / アディポネクチン / 骨密度 / 血管障害 / 初代培養肝細胞 / ホスホリパーゼA_2 / 血小板活性化因子 / イノシトールミリン酸 / アラキドン酸 / エーテルリン脂質 / ホスホリパーゼC / 膜安定性 / 4,1蛋白 / Caイオン / 結晶 / X線 / 構造 / 異性化 / 酵素 / 結晶化 / X線解析 / Crystal / X-ray / Structure / Isomerization / Enzyme / 人工関節ゆるみ / 液性因子 / 異物反応 / 骨芽細胞 / 人工関節のゆるみ / 貧食 / loosening / soluble factors / foreign body reaction / osteoblast / cell proliferation / 正常眼球 / 胎生期眼球 / 角膜穿孔 / 実験的自己免疫性ぶどう膜炎 / 増殖性硝子体網膜症 / 実験的自己免疫性ぶとう膜炎 / 角膜穿孔剤 / embryonic eye / normal eye / corneal perforative wound / experimental autoimmune uveoretinitis / proliferative vitreoretinopathy / 蛋白質結晶構造解析 / DNA結合蛋白質 / 転写因子 / Crystal structure analysis of protein / DNA-binding proteins / Transcription factor / 壁細胞 / parital cell / 仮骨延長 / 下顎骨 / 犬 / 膜性骨下 / 膜性骨化 / ラット / ビーグル犬 / initial gap / distraction osteogenesis / mandible / dog / cytokines / membranous bone / 歯周病 / リポポリサッカライド / Macrophage migration inhibitory factor (MIF) / Fibroblast / Periodontal disease / Lipopolysaccharide / 皮膚 / 炎症 / 紫外線 / 創傷 / 腫瘍 / 乾癬 / メラノーマ / 増殖因子 / macrophage / cytokine / skin / inflammation / atopy / ultraviolet / wound / グルココルチコイド / 肺障害 / LUNG INJURY / lipopolysaccharide / Transgenic mice / NEUTROPHIL / GLUCOCORTICOIDS / 創傷治癒 / ケロイド / 細胞外基質 / アポトーシス / 細胞周期 / transgenic mouse / wound healing / keloid / extracellular matrix / cellular proliferation / 腱 / 靭帯 / 力学特性 / 靭帯再建術 / コラゲン / 再構築現象 / 繊維芽細胞 / 細胞外マトリックス / 膝蓋腱 / 自家腱移植 / リモデリング / 細胞外マトリクス / Tendon / Ligament / Mechanical properties / Ligament reconstruction / Collagen / Remodeling / Fibroblasts / Extracellular matrix / DNAワクチン / 関節リウマチ / ワクチン / 慢性関節リウマチ / DNA vaccine / rheumatoid arthritis / マイクロRNA / 食品因子センシング / 難吸収性食品因子 / リキッドバイオプシー / 食機能実行分子 / 機能性RNA / 細胞外小胞 / 機能性フードペアリング / 食品因子センサー Less

食機能実行分子とその機能的相互作用の統合的理解
- Principal Investigator
  
  立花宏文
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section F
- Research Institution
  Kyushu University
Examination of the Latent Health Dysfunction due to Lean Body-frame in Japanese Young Women
- Principal Investigator
  
  HIROKI Satoh
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Hokkaido Information University
炎症・免疫応答におけるマクロファージ遊走阻止因子(MIF)の機能の解明Principal Investigator
- Principal Investigator
  
  西平順
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
The development of MIF vaccine and its therapeutic effect on murine arthritis model
- Principal Investigator
  
  ONODERA Shin
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hokkaido University
遺伝子改変動物による敗血症性ショックにおけるマクロファージ遊走阻止因子機能の解明
- Principal Investigator
  
  丸藤哲
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hokkaido University
THE ROLE OF EXTRINSIC INFROBLASTS IN THE RTEMODELING OF THE PATELLAR TENDON MATRIX
- Principal Investigator
  
  TOHYAMA Harukazu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  HOKKAIDO UNIVERSITY
癌細胞浸潤及び血管新生におけるマクロファージ遊走阻止因子の機能に関する基礎的研究Principal Investigator
- Principal Investigator
  
  西平順
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
The Analysis of Macrophage Migration Inhibitory Factor (MIF) Functions using MIF Transgenic MicePrincipal Investigator
- Principal Investigator
  
  NISHIHIRA Jun
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  HOKKAIDO UNIVERSITY
Analysis of MIF function in wound healing using transgenic mouse
- Principal Investigator
  
  SASAKI Satoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  HOKKAIDO UNIVERSITY
癌細胞浸潤及び血管新生におけるマクロファージ遊走阻止因子の機能に関する基礎的研究Principal Investigator
- Principal Investigator
  
  西平順
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
難治性気管支喘息の病因解明と抗マクロファージ遊走阻止因子抗体による治療の試み
- Principal Investigator
  
  NISHIMURA Masaharu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hokkaido University
Role of MIF in Lung Injury in Transgenic Mice
- Principal Investigator
  
  MIYAMOTO Kenji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  HOKKAIDO UNIVERSITY
A study of regeneration of membranous bone - Interaction of Macrophage migration inhibitory factor with other cytokines -
- Principal Investigator
  
  SUGIHARA Tsuneki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  HOKKAIDO UNIVERSITY
A pathophysiological role of macrophage migration
- Principal Investigator
  
  SAKAMOTO Wataru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  HOKKAIDO UNIVERSITY
Role for macrophage migration inhibitory factor (MIF) in the skin and contribution to the skin diseases.
- Principal Investigator
  
  TADAMICHI Shimizu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
急性肺損傷における抗MIF抗体の防御機構に関する研究
- Principal Investigator
  
  MIYAMOTO Kenji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Hokkaido University
Expression and significance of MIF in the ocular tissue.
- Principal Investigator
  
  TAGAWA Yoshitsugu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  HOKKAIDO UNIVERSITY
RNA polymerase activation mechanism by regulatory proteins
- Principal Investigator
  
  TANAKA Isao
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  HOKKAIDO UNIVERSITY
The role of macrophage migration inhibitory factor in endotoxin shockPrincipal Investigator
- Principal Investigator
  
  NISHIHIRA Jun
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
Helicobacter pylori and its association with gastric cancer
- Principal Investigator
  
  TAKEDA Hiroshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  HOKKAIDO UNIVERSITY
A biochemical study on the role of soluble factors in the loosening of artificial joint.
- Principal Investigator
  
  SUZUKI Koji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  HOKKAIDO UNIVERSITY
The role of macrophage migration inhibitory factor in endotoxin shockPrincipal Investigator
- Principal Investigator
  
  NISHIHIRA Jun
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
Structure analysis of macrophage migration inhibitory factor
- Principal Investigator
  
  TANAKA Isao
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Hokkaido University
時間分解顕微蛍光法によるトランスミッタ-放出機構の解析
- Principal Investigator
  
  石俊輝雄
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
イノシト-ル燐脂質代謝を介するグリコフォリンの赤血球膜機能調節機構の解明
- Principal Investigator
  
  石橋輝雄
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
イノシトール燐脂質代謝を介するグリコフォリンの赤血球膜機能調節機構の解明
- Principal Investigator
  
  石橋輝雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
PAFによるマクロファージ系細胞特に肝類洞細胞の活性化と動脈硬化症発生機構の関連
- Principal Investigator
  
  石橋輝雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Hokkaido University

All 2014 2004

All Journal Article Patent

[Journal Article] 若年日本人女性のやせ型体型が潜在的健康障害に及ぼす影響の解明2014
- Author(s)
  佐藤浩樹, 西平順, 他
- Journal Title
  
  北海道情報大学紀要
  
  Volume: 25(2) Pages: 49-54
- NAID
  40020079025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500811
[Journal Article] 若年日本人女性のやせ型体型が潜在的健康障害に及ぼす影響の解明2014
- Author(s)
  佐藤　浩樹、西平　順、吉岡　英治
- Journal Title
  
  北海道情報大学紀要
  
  Volume: 第25巻第2号 Pages: 49-54
- NAID
  40020079025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500811
[Journal Article] Increased expression of macrophage migration inhibitory factor during fracture healing in rats.2004
- Author(s)
  Onodera S, Nishihira J, Yamazaki M, Ishibashi T, Minami A
- Journal Title
  
  Histochem Cell Biol 121
  
  Pages: 209-217
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591560
[Journal Article] Inhibition of Joint Inflammation and Destruction Induced by Anti-type II Collagen Antibody/Lipopolysaccharide (LPS)-induced Arthritis in Mice due to Deletion of Macrophage Migration Inhibitory Factor (MIF).2004
- Author(s)
  Ichiyama H, Onodera S, Nishihira J, Ishibashi T, Nakayama T, Minami A, Yasuda K, Tohyama H
- Journal Title
  
  Cytokine 26
  
  Pages: 187-194
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591560
[Journal Article] Macrophage Migration Inhibitory Factor (MIF) Up-regulates Expression of Interleukin (IL)-8 mRNA in Synovial Fibroblasts of Rheumatoid Arthritis ; Common Transcriptional Regulatory Mechanism between IL-8 and IL-1β.2004
- Author(s)
  Onodera S, Nishihira J, Koyama Y, Majima T, Aoki Y, Ichiyama H, Ishibashi T, Minami A
- Journal Title
  
  Arthritis Rheum 50
  
  Pages: 1437-1447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591560
[Journal Article] Up-regulation of Macrophage Migration-inhibitory Factor Expression after Compression-induced Spinal Cord Injury in Rats.2004
- Author(s)
  Koda M, Nishio Y, Hashimoto M, Kamada T, Koshizuka S, Yoshinaga K, Mariya H, Onodera S, Nishihira J, Yamazaki M
- Journal Title
  
  Acta Neuropathologica 108
  
  Pages: 31-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591560
[Patent] DNAワクチン2004
- Inventor(s)
  西平順, 小山芳一, 小野寺伸
- Industrial Property Rights Holder
  西平順, 小山芳一, 小野寺伸
- Industrial Property Number
  2004-280051
- Filing Date
  2004-09-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591560
[Patent] DNAワクチン2004
- Inventor(s)
  西平順, 小山芳一, 小野寺伸
- Industrial Property Rights Holder
  西平順, 小山芳一, 小野寺伸
- Industrial Property Number
  2004-280051
- Filing Date
  2004-09-27
- Data Source
  KAKENHI-PROJECT-15591560

1. 石橋輝雄 (60001872)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. IWABUCHI Kazuya (20184898)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TANAKA Isao (70093052)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KOYAMA Yoshikazu (90186841)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. NISHIMURA Masaharu (00208224)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 高桑雄一 (40113740)

# of Collaborated Projects: 3 results

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7. MIYAMOTO Kenji (50190814)

# of Collaborated Projects: 2 results

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8. INOUE Yoshiro (20051584)

# of Collaborated Projects: 2 results

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9. SUGIHARA Tsuneki (20002157)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SASAKI Satoru (40301907)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 小林正伸 (80241321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. HIROKI Satoh (40507216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. YOSHIOKA Eiji (70435957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. SUZUKI Koji (90235945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MATSUNO Takeo (10165847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAGAWA Yoshitsugu (40109426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MATSUDA Akira (00312348)

# of Collaborated Projects: 1 results

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18. OGASAWARA Kazumasa (20169163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKAGAWA Atsushi (20188890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKEDA Hiroshi (60261294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SAKAMOTO Wataru (30001952)

# of Collaborated Projects: 1 results

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22. KAWANAMI Masamitsu (10133761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KOHGO Takao (80001949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TADAMICHI Shimizu (70260396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMAMOTO Yuhei (70271674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. TOHYAMA Harukazu (60301884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MAJIMA Tokifumi (30241334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. YASUDA Kazunori (20166507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ONODERA Shin (00359481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
30. 田代邦雄 (90002154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 荒磯恒久 (30151145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 南須原康行 (30322811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 丸藤哲 (30125306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 松田直之 (50332466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 立花宏文 (70236545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 藤村由紀 (20390304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 村田希 (50808110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 山崎正夫 (80381060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. YOKOYAMA Toichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NISHIHIRA Jyun 西平 順

西平 順 ニシヒラ ジュン

NISHIHIRA Jun 西平 順

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炎症・免疫応答におけるマクロファージ遊走阻止因子(MIF)の機能の解明Principal Investigator

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癌細胞浸潤及び血管新生におけるマクロファージ遊走阻止因子の機能に関する基礎的研究Principal Investigator

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The Analysis of Macrophage Migration Inhibitory Factor (MIF) Functions using MIF Transgenic MicePrincipal Investigator

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癌細胞浸潤及び血管新生におけるマクロファージ遊走阻止因子の機能に関する基礎的研究Principal Investigator

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NISHIHIRA Jyun 西平順

西平順ニシヒラジュン

NISHIHIRA Jun 西平順