OGASAWARA Kazumasa 小笠原一誠

… Alternative Names

小笠原一誠オガサワラカズマサ

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Researcher Number	20169163
Other IDs
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Affiliation (based on the past Project Information) *help	2009 – 2019: 滋賀医科大学, 医学部, 教授 2005 – 2006: 滋賀医科大学, 医学部, 教授 2001: 滋賀医科大学, 医学部, 教授 1999: SHIGA UNIVERSITY OF MEDICAL SCIENCE, DEPARTMENT OF 2nd PATHOLOGY, PROFESSOR, 医学部, 教授 1997 – 1999: 北海道大学, 免疫科学研究所, 助教授 … More 1991 – 1994: 北海道大学, 免疫科学研究所, 助教授 1991 – 1992: 北海道大学, 免疫科学研究所・病理部門, 助教授 1989: Hokkaido University, Institute of Immunological Science, Associate professor, 免疫科学研究所, 助教授 1988: 北海道大学, 免疫化学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Immunology / Gastroenterology / Experimental pathology / Laboratory animal science / Laboratory animal science / Biological Sciences Except Principal Investigator Experimental pathology / Experimental pathology / Immunology / Urology … More / Dermatology / Applied veterinary science / Ophthalmology / Laboratory animal science / Laboratory animal science Less
Keywords	Principal Investigator MHC / カセットセオリー / ペプチドワクチン / カニクイザル / CTL / エピトープ / アグレトープ / NP / HA / cassette theory … More / iPS細胞 / 癌 / 抗CD40抗体 / ヘムアグルチニン / 移植・再生医療 / BM-MSC / IL-10 / 間葉系幹細胞 / DSS腸炎 / cynomolgus macaque / iPSC / MSC / DSS colitis / anti-CD40 antibody / newly emerged influenza virus / peptide vaccine / 新型インフルエンザウイルス / haemagglutinin / DQw6 transgenic mice / epitope / agretope / tri-molecular complex / カセットセオリ- / エピト-プ / アグレト-プ / DQw6トランスジェニックマウス / 3分子複合体 / 免疫抑制 / 体外循環 / NK細胞 / LAP陽性単球 / 内膜症サル / Treg / 免疫抑制細胞除去カラム / LAP陽性細胞 / 子宮内膜症 / iPS 細胞 / 免疫学 / バイオテクノロジー / 生体機能利用 / ウイルス / RL♂1 / 抗CTLA-4抗体 / ペプチド / 腫瘍関連抗原 / 三分子複合体 / TCR / インフルエンザ / インフルエンザウイルス … More Except Principal Investigator 霊長類モデル / 骨髄キメラ / Negative selection / Positive selection / 病理学 / 免疫学 / インフルエンザウイルス / MCP-1 / マクロファージ遊走阻止因子 / aly / トランスジェニックマウス / TCR / CD4^-8^- / 胸腺 / negative selection / BCG / 膀胱癌 / 制御性T細胞 / B10細胞 / 抑制性 / 類天疱瘡 / 天疱瘡 / IL-35 / CD26 / IL-10 / B10 / 抑制性B細胞 / 感染症 / ウイルス / 次世代シーケンサー / 高病原性鳥インフルエンザ / 遺伝子多型 / ゲノム / サイトカインストーム / Induction of self-tolerance / Self recognition / Thymocytes differentiation / Bone marrow chimera / T細胞抗原レセプター / ネガティブセレクション / T細胞レセプタ- / 自己寛容誘導 / ポジティブセレクション / 自己認識 / 胸腺細胞分化 / diagnosis / antiviral / vaccine / global surveillance / influenza viruses / 診断 / 抗ウイルス薬 / ワクチン / グローバルサーベイランス / AIF-1 / ATHEROSCLEROSIS / TRANSGENIC MICE / MIF / TYROSINE KINASE / INFLAMMATION / MACROPHAGE / 肉芽腫 / アンチセンス / チロシンリン酸化 / アログラフト炎症因子―1 / MCP―1 / アログラフト炎症因子-1 / 動脈硬化症 / チロシンキナーゼ / 炎症 / マクロファージ / proliferative vitreoretinopathy / experimental autoimmune uveoretinitis / corneal perforative wound / normal eye / embryonic eye / macrophage migration inhibitory factor / 角膜穿孔剤 / 実験的自己免疫性ぶとう膜炎 / 増殖性硝子体網膜症 / 実験的自己免疫性ぶどう膜炎 / 角膜穿孔 / 胎生期眼球 / 正常眼球 / aly mice / autoimmune disease / - mice / ZAP-70= / TCR transgenic mice / NK-T cell / alyマウス / 負の選択 / 正の選択 / DO.10トランスジェニックマウス / NK-T前駆細胞 / ZAP-70- / -マウス / β2M- / 自己免疫 / ZAP-70ノックアウトマウス / TCRトランスジェニックマウス / NK-T細胞 / Fas antigen / NK1^+TCRalphabeta cell / Programd cell death / T cell differentiation / Thymus / CD4^+8^-T細胞 / NK1.1^+TCRαβ^+胸腺細胞 / programmed cell death / positive selection / Fas抗原 / NK1.1^+TCRαβ胸腺細胞 / Programmed cell death / T細胞分化 / 遺伝子編集 / レンチウイルスベクター / ゲノム編集 / トランスレーショナルリサーチ / 癌 / 老化 / 自己免疫疾患 / リンパ球 / iPS細胞 / 抗体療法 / インフルエンザ / 免疫不全 / ペプチド / 免疫抑制 / 抗体医薬 / 薬剤感受性 / 多型 / 再生医療 / MHC / カニクイザル / 遺伝育種 / CD4^+8^ーT細胞 / clonal anergy / GVL / GVHR / 白血病 / 骨髄移植 Less

Treatment of DSS colitis with MSCs derived from MHC-homozygous iPSCs with using cynomolgus macaquePrincipal Investigator
- Principal Investigator
  
  Ogasawara Kazumasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Shiga University of Medical Science
Treatment for autoimmune skin diseases with B10 cells
- Principal Investigator
  
  Fujimoto Noriki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Shiga University of Medical Science
Search for host factors in severe influenza virus infection using a nonhuman primate model
- Principal Investigator
  
  Itoh Yasushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science
Development of a premature aging syndrome non-human primate model
- Principal Investigator
  
  Itoh Yasushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Shiga University of Medical Science
Treatment by a column absorbing immunosuppressing cells in macaques with endometriosisPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Kazumasa
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Shiga University of Medical Science
Regulatory T cells in intravesical BCG therapy for non-muscle invasive bladder cancer
- Principal Investigator
  
  Narita Mitsuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Development of a non-human primate autoimmune model using autoreactive lymphocytes derived from induced pluripotent stem cells
- Principal Investigator
  
  ITOH Yasushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science
Establishment of a macaque cancer model using cancer cells derived from MHC homozygous macaque iPS cellsPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Kazumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shiga University of Medical Science
Antibody therapy against novel influenza virus infection using anImmunosuppressed non-human primate model
- Principal Investigator
  
  ITOH Yasushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science
Elucidation of MHC polymorphism information in cynomolgus macaque(Macaca Fascicularis)
- Principal Investigator
  
  SHHNA Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokai University
Ecology and pandemic planning of animal influenza virus
- Principal Investigator
  
  KIDA Hiroshi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
分泌型TGF-βレセプターII遺伝子導入アデノウイルス投与による腫瘍拒絶の試みPrincipal Investigator
- Principal Investigator
  
  小笠原一誠
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Shiga University of Medical Science
リポソーム封入癌関連ペプチドと抗CD40抗体投与で誘導されるCTLの抗腫癌効果Principal Investigator
- Principal Investigator
  
  小笠原一誠
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Shiga University of Medical Science
Preparation of peptide vaccines according to the cassette theory against newly emerged influenza virusPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Kazumasa
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  SHIGA UNIVERSITY OF MEDICAL SCIENCE
  Hokkaido University
MANIPULATION OF INFLAMMATORY RESPONSES BY MODULATION OF MACROPHAGE FUNCTIONS.
- Principal Investigator
  
  IWABUCHI Kazuya
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  HOKKAIDO UNIVERSITY
Differentiation and function of NKR-P1ィイD1+ィエD1 TCRαβィイD1+ィエD1 thymocytes
- Principal Investigator
  
  ONOE Kazunori
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  HOKKAIDO UNIVERSITY
Expression and significance of MIF in the ocular tissue.
- Principal Investigator
  
  TAGAWA Yoshitsugu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  HOKKAIDO UNIVERSITY
ペプチド抗原を使用した人為的免疫制御の試みPrincipal Investigator
- Principal Investigator
  
  小笠原一誠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
ペプチド抗原+MHC分子を認識するTCRの解析Principal Investigator
- Principal Investigator
  
  小笠原一誠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
ペプチド抗原を使用した人為的免疫制御の試みPrincipal Investigator
- Principal Investigator
  
  小笠原一誠
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
移植細胞対白血病(GVL)反応を応用した骨髄移植による白血病治療の基礎的研究
- Principal Investigator
  
  ONOE Kazunori
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
A study on T cell differentiation, selection and T cell receptors
- Principal Investigator
  
  ONOE Kazunori
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Detection of amino acid motifs on the agretopes of antigens highly bound to MHC moleculesPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Kazumasa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
Study on self recognition system of T lymphocytes and structural analysis of TCR : CD3 Complex
- Principal Investigator
  
  ONOE Kazunori
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Inactivated whole virus particle vaccine with potent immunogenicity and limited IL-6 production is ideal for influenza2019
- Author(s)
  Sekiya T, Mifsud EJ, Ohno M, Nomura N, Sasada M, Fujikura D, Daito T, Shingai M, Ohara Y, Nishimura T, Endo M, Mitsumata R, Ikeda T, Hatanaka H, Kitayama H, Motokawa K, Sobue T, Suzuki S, Itoh Y, Brown LE, Ogasawara K, Kino Y, Kida H
- Journal Title
  
  Vaccine
  
  Volume: 37 Issue: 15 Pages: 2158-2166
- DOI
  10.1016/j.vaccine.2019.02.057
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04720, KAKENHI-PROJECT-18K07135, KAKENHI-PROJECT-19H03148, KAKENHI-PROJECT-16K08570, KAKENHI-PROJECT-18K15117
[Journal Article] Potential Risk of Repeated Nasal Vaccination that Induces Allergic Reaction with Mucosal IgE and Airway Eosinophilic Infiltration in Cynomolgus Macaques infected with H5N1 Highly Pathogenic Avian Influenza Virus2017
- Author(s)
  Nakayama M, Itoh Y, Shichinohe S, Nakabayashi R, Ishigaki H, Sakoda Y, Le QM, Kawaoka Y, Kida H, Ogasawara K
- Journal Title
  
  Vaccine
  
  Volume: 35 Pages: 1008-1017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640053
[Journal Article] Potential Risk of Repeated Nasal Vaccination that Induces Allergic Reaction with Mucosal IgE and Airway Eosinophilic Infiltration in Cynomolgus Macaques infected with H5N1 Highly Pathogenic Avian Influenza Virus.2017
- Author(s)
  Nakayama M, Itoh Y, Shichinohe S, Nakabayashi R, Ishigaki H, Sakoda Y, Le QM, Kawaoka Y, Kida H, Ogasawara K
- Journal Title
  
  Vaccine
  
  Volume: 35 Issue: 7 Pages: 1008-1017
- DOI
  10.1016/j.vaccine.2017.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04720
[Journal Article] カニクイザルモデルを用いた免疫抑制状態における鳥インフルエンザウイルスの病原性の解明2017
- Author(s)
  伊藤靖、小笠原一誠
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 68 Pages: 31-37
- Data Source
  KAKENHI-PROJECT-15H04720
[Journal Article] Surgical technique for allogeneic uterus transplantation in macaques2016
- Author(s)
  Obara H, Kisu I, Kato Y, Yamada Y, Matsubara K, Emoto K, Adachi M, Matoba Y, Umene K, Nogami Y, Banno K, Tsuchiya H, Itagaki I, Kawamoto I, Nakagawa T, Ishigak Hi, Itoh Y, Ogasawara K, Saiki Y, Sato S-i, Nakagawa N, Shiina T, Aoki D, Kitagawa Y
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 35989-35989
- DOI
  10.1038/srep35989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-15K10084
[Journal Article] Sensitization with vaccinia virus harboring hemagglutinin recovers the immune potential against highly pathogenic H5N1 influenza virus in non-human primates2016
- Author(s)
  Fumihiko Yasui, Yasushi Itoh, Ai Ikejiri, Masahiro Kitabatake, Nobuo Sakaguchi, Keisuke Munekata, Shintaro Shichinohe, Yukiko Hayashi, Hirohito Ishigaki, Misako Nakayama, Yoshihiro Sakoda, Hiroshi Kida, Kazumasa Ogasawara, *Michinori Kohara
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 37915-37915
- DOI
  10.1038/srep37915
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01272, KAKENHI-PROJECT-15H04739, KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26860776, KAKENHI-PROJECT-15K09532, KAKENHI-PROJECT-15K15146, KAKENHI-PROJECT-15H04720
[Journal Article] Vaccination against H9N2 avian influenza virus reduces bronchus-associated lymphoid tissue formation in cynomolgus macaques after intranasal virus challenge infection2016
- Author(s)
  Nakayama M, Ozaki H, Itoh Y, Soda K, Ishigaki H, Okamatsu M, Sakoda Y, Park C-H, Tsuchiya H, Kida H, Ogasawara K
- Journal Title
  
  Pathology International
  
  Volume: 66 Issue: 12 Pages: 678-686
- DOI
  10.1111/pin.12472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-15H04720
[Journal Article] Comparison of pathogenicities of H7 avian influenza viruses via intranasal and conjunctival inoculation in cynomolgus macaques2016
- Author(s)
  Shichnohe S, Itoh Y, Nakayama M, Ozaki H, Soda K, Ishigaki H, Okamatsu M, Sakoda Y, Kida H, Ogasawara K
- Journal Title
  
  Virology
  
  Volume: 493 Pages: 31-38
- DOI
  10.1016/j.virol.2016.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26850178, KAKENHI-PROJECT-15H04720
[Journal Article] Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body2016
- Author(s)
  Seita Y, Tsukiyama T, Iwatani C, Tsuchiya H, Matsushita J, Azami T, Okahara J, Nakamura S, Hayashi Y, Hitoshi S, Itoh Y, Imamura T, Nishimura M, Tooyama I, Miyoshi H, Saitou M, Ogasawara K, Sasaki E, Ema M
- Journal Title
  
  Scientific Reports
  
  Volume: 2 Issue: 1 Pages: 24868-24868
- DOI
  10.1038/srep24868
- NAID
  130007023590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-15K21080, KAKENHI-PROJECT-16H04671, KAKENHI-PROJECT-26430070, KAKENHI-PROJECT-26870282, KAKENHI-PROJECT-16K14578
[Journal Article] Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing2015
- Author(s)
  Shiina T, Yamada Y, Aarnink A, Suzuki S, Masuya A, Ito S, Ido D, Yamanaka H, Iwatani C, Tsuchiya H, Ishigaki H, Itoh Y, Ogasawara K, Kulski JK, Blancher A
- Journal Title
  
  Immunogenetics
  
  Volume: 67 Issue: 10 Pages: 563-578
- DOI
  10.1007/s00251-015-0867-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04720
[Journal Article] Emergence of H7N9 Influenza A Virus Resistant to Neuraminidase Inhibitors in Nonhuman Primates2015
- Author(s)
  Itoh Y, Shichinohe S, Nakayama M, Igarashi M, Ishii A, Ishigaki H, Ishida H, Kitagawa N, Sasamura T, Shiohara M, Doi M, Tsuchiya H, Nakamura S, Okamatsu M, Sakoda Y, Kida H, Ogasawara K
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 59(8) Issue: 8 Pages: 4962-4973
- DOI
  10.1128/aac.00793-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25450417, KAKENHI-PROJECT-15H04720
[Journal Article] The zoonotic potential of avian influenza viruses isolated from wild waterfowl in Zambia2014
- Author(s)
  Simulundu E, Nao N, Yabe J, Muto NA, Sithebe T, Sawa H, Manzoor R, Kajihara M, Muramatsu M, Ishii A, Ogawa H, Mweene AS, Takada A
- Journal Title
  
  Arch. Virol.
  
  Volume: 159 Issue: 6 Pages: 2633-2640
- DOI
  10.1371/journal.ppat.1004192
- NAID
  120005656330
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390110, KAKENHI-PROJECT-25450417, KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26850178
[Journal Article] Efficacy of repeated intravenous administration of peramivir against highly pathogenic avian influenza A (H5N1) virus in cynomolgus macaques.2014
- Author(s)
  Kitano M, Itoh Y, Ishigaki H, Nakayama M, Ishida H, Pham VL, Arikata M, Shichinohe S, Tsuchiya H, Kitagawa N, Kobayashi M, Yoshida R, Sato A, Le QM, Kawaoka Y, Ogasawara K
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 58 Issue: 8 Pages: 4795-4803
- DOI
  10.1128/aac.02817-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640053
[Journal Article] Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses.2014
- Author(s)
  Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, Matsuoka Y, Noda T, Fukuyama S, Ogasawara K, Kitano H, Kawaoka Y.
- Journal Title
  
  Journal of Virlogy
  
  Volume: 88(16) Issue: 16 Pages: 8981-8997
- DOI
  10.1128/jvi.00907-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J01509, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23590145, KAKENHI-PROJECT-25670216, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-26850180
[Journal Article] Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine2013
- Author(s)
  Nakayama M, Shichinohe S, Itoh Y, Ishigaki H, Kitano M, Arikata M, Pham VL, Ishida H, Kitagawa N, Okamatsu M, Sakoda Y, Ichikawa T, Tsuchiya H, Nakamura S, Le QM, Ito M, Kawaoka Y, Kida H, Ogasawara K
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 12 Pages: e82740-e82740
- DOI
  10.1371/journal.pone.0082740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659201
[Journal Article] Pathogenicity of pandemic H1N1 influenza A virus in immunocompromised cynomolgus macaques2013
- Author(s)
  Pham VL, Nakayama M, Itoh Y, Ishigaki H, Kitano M, Arikata M, Ishida H, Kitagawa N, Shichinohe S, Okamatsu M, Sakoda Y, Tsuch -iya H, Nakamura S, Kida H, Ogasawara K
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 9 Pages: e75910-e75910
- DOI
  10.1371/journal.pone.0075910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659201
[Journal Article] Epidemiology of Hepatitis E Virus in Indoor-Captive Cynomolgus Monkey Colony2012
- Author(s)
  Nakamura S, Tsuchiya H, Okahara N, Nakagawa T, Ohara N, Yamamoto H, Li T-C, Takeda N, Ogasawara K, Torii R
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 74 Issue: 3 Pages: 279-283
- DOI
  10.1292/jvms.11-0394
- NAID
  130001190495
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300143
[Journal Article] Memory immune responses against pandemic (H1N1) 2009 influenza virus induced by a whole particle vaccine in ynomolgus monkeys carrying Mafa-A*052:022012
- Author(s)
  Arikata M, Itoh Y, Okamatsu M, Maeda T, Shiina T, Tanaka K, Suzuki S, Nakayama M, Sakoda Y, Ishigaki H, Takada A, Ishida H, Soda K, Pham VL, Tsuchiya H, Nakamura S, Torii R, Shimizu T, Inoko H, Ohkubo I, Kida H, Ogasawara K
- Journal Title
  
  PLos ONE
  
  Volume: 7 Issue: 5 Pages: e37220-e37220
- DOI
  10.1371/journal.pone.0037220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300143, KAKENHI-PROJECT-22390076, KAKENHI-PROJECT-23659201, KAKENHI-PLANNED-22133002
[Journal Article] Memory Immune Responses Against Pandemic 1(H1N1) 2009 Influenza Virus Induced by a Whole Particle Vaccine in Cynomolgus Monkeys Carrying Mafa-A1 052 : 022012
- Author(s)
  Arikata M, Itoh Y, Okamatsu M, Maeda T, Shiina T, Tanaka K, Suzuki S, Nakayama M, Sakoda Y, Ishigaki H, Takada A, Ishida H, Soda K, Pham VL, Tsuchiya H, Nakamura S, Torii R, Shimizu T, Inoko H, Ohkubo I, Kida H, Ogasawara K
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300155
[Journal Article] Efficacy of single intravenous injection of peramivir against influenza B virus infection in ferrets and cynomolgus macaques2011
- Author(s)
  Kitano M, Itoh Y, Kodama M, Ishigaki H, Nakayama M, Ishida H, Baba K, Noda T, Sato K, Nihashi Y, Kanazu T, Yoshida R, Torii R, Sato A, Ogasawara K
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: Vol.55 Issue: 11 Pages: 4961-4970
- DOI
  10.1128/aac.00412-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390076, KAKENHI-PROJECT-23659201, KAKENHI-PROJECT-23790442
[Journal Article] Establishment of a cynomolgus macaque model of influenza B virus infection2010
- Author(s)
  Kitano M, Itoh Y, Kodama M, Ishigaki H, Nakayama M, Nagata T, Ishida H, Tsuchiya H, Torii R, Baba K, Yoshida R, Sato A, Ogasawara K
- Journal Title
  
  Virology
  
  Volume: Vol. 407 Issue: 2 Pages: 178-184
- DOI
  10.1016/j.virol.2010.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390076
[Journal Article] MHC class I A loci polymorphism and diversity in three Southeast Asian populations of cynomolgus macaque2009
- Author(s)
  Kita YF, Hosomichi K, Kohara S, Itoh Y, Ogasawara K, Tsuchiya H, Torii R, Inoko H, Blancher A, Kulski JK, Shiina T
- Journal Title
  
  Immunogenetics
  
  Volume: 61 Pages: 635-648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300155
[Patent] カニクイザルMHC全遺伝子ホモ接合体を作成するためのキット及び方法2011
- Inventor(s)
  小笠原一誠、鳥居隆三、椎名隆
- Industrial Property Rights Holder
  学校法人東海大学、国立大学法人滋賀医科大学
- Filing Date
  2011-05-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21300155
[Patent] カニクイザルMHC全遺伝子ホモ接合体を作成するためのキット及び方法2010
- Inventor(s)
  椎名隆, 小笠原一誠, 鳥居隆三
- Industrial Property Rights Holder
  東海大学, 滋賀医科大学
- Filing Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-21300155
[Patent] MHChomozygousカニクイザルの作成2010
- Inventor(s)
  小笠原一誠、鳥居隆三、椎名隆
- Industrial Property Rights Holder
  滋賀医科大学
- Filing Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-22300143
[Patent] カニクイザル MHC 全遺伝子ホモ接合体を作成するためのキット及び方法2010
- Inventor(s)
  小笠原一誠、鳥居隆三、椎名隆
- Industrial Property Rights Holder
  滋賀医科大学
- Industrial Property Number
  2010-105956
- Filing Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-22300143
[Presentation] サルモデルを用いた季節性インフルエンザに対する不活化全粒子ワクチンの有効性評価2018
- Author(s)
  伊藤靖、鈴木沙織、石垣宏仁、仲山美沙子、新開大史、大東卓史、野村直樹、喜田宏、小笠原一誠
- Organizer
  第22回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04720
[Presentation] 霊長類を用いた疾患モデルにおける炎症反応の解析2018
- Author(s)
  伊藤靖、石垣宏仁、仲山美沙子、小笠原一誠
- Organizer
  第107回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04720
[Presentation] Viral pneumonia caused by H5N1 highly pathogenic avian influenza virus in immunosuppressed macaques2017
- Author(s)
  Yasushi Itoh, Misako Nakayama, Hirohito Ishigaki, Kazumasa Ogasawara
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15H04720
[Presentation] 子宮内膜症カニクイザルの単球とNK細胞の挙動2016
- Author(s)
  中村紳一朗、仲山美沙子、塚本真由美、土屋英明、野々口耕介、小笠原一誠、森崇英
- Organizer
  第37回日本エンドメトリオーシス学会
- Place of Presentation
  東京
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-26640054
[Presentation] 免疫抑制カニクイザルを用いたパンデミックH1N1亜型インフルエンザウイルスの病原性の解析2013
- Author(s)
  伊藤靖、Pham Van Loi、仲山美沙子、七戸新太郎、石垣宏仁、有方雅彦、石田英晃、北川直子、岡松正敏、迫田義博、喜田宏、小笠原一誠
- Organizer
  第27回インフルエンザ研究者交流の会シンポジウム
- Place of Presentation
  北海道大学(北海道)
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] Pathogenicity of pandemic (H1N1) 2009 influenza A virus in immunosuppressed cynomolgus monkeys2013
- Author(s)
  Itoh Y, Nakayama M, Ishigaki H, Ogasawara K
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2013-12-12
- Data Source
  KAKENHI-PROJECT-23659201
[Presentation] カニクイザル iPS 細胞由来癌細胞株を用いた、担癌カニクイザルモデルの作製2013
- Author(s)
  石垣宏仁、仲山美沙子、伊藤靖、小笠原一誠
- Organizer
  第102回病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22300143
[Presentation] Therapeutic efficacy of a human-mouse chimeric anti-H5 hemagglutinin antibody on lethal H5N1 highly pathogenic avian influenza virus infection in cynomolgus macaques2012
- Author(s)
  Itoh Y, Ishigaki H, Nakayama M, Ishida H, Ogasawara K
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23659201
[Presentation] Therapeutic efficacy of a human-mouse chimeric anti-H5 hemagglutinin antibody on lethal H5N1 highly pathogenic avian influenza virus infection in cynomolgus macaques2012
- Author(s)
  Itoh Y, Ishigaki H, Nakayama M, Ishida H, Ogasawara K.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] An inactivated whole particle vaccine induced memory immune responses against pandemic (H1N1) 2009 influenza virus in cynomolgus monkeys carrying Mafa-A1*052:022012
- Author(s)
  Itoh Y, Arikata M, Okamatsu M, Nakayama M, Sakoda Y, Ishigaki H, Takada A, Ishida H, Soda K, Pham VL, Kida H, Ogasawara K.
- Organizer
  第16回日本ワクチン学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] Influenza virus peptides specifically bound to cynomolgus macaque major histocompatibility complex class I Mafa-A1*52022011
- Author(s)
  Itoh Y, Arikata M, Ishigaki H, Nakayama M, Ishida H, Ogasawara
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] Identification of pandemic influenza virus NP peptides bound to cynomolgus macaque MHC class I Mafa-A1*5202 and stimulating CTL responses2011
- Author(s)
  Itoh Y, Arikata M, Maeda T, Shiina T, Ishigaki H, Takada A, Okamatsu M, Sakoda Y, Nakayama M, Kida H, Ogasawara K
- Organizer
  XV International Congress of Virology
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] Elucidation of Genomic Structure and Diversity of the Macaca Fascicularis MHC2011
- Author(s)
  Shiina T, Suzuki S, Tanaka K, Yamanaka H, Nakagawa H, Ota M, Torii R, Ogasawara K, Inoko H, Blancher A
- Organizer
  SMBE2011
- Place of Presentation
  Kyoto University
- Year and Date
  2011-07-27
- Data Source
  KAKENHI-PROJECT-21300155
[Presentation] Influenza virus peptides specifically bound to cynomolgus macaque major histocompatibility complex class I Mafa-A1*52022011
- Author(s)
  Itoh Y, Arikata M, Ishigaki H, Nakayama M, Ishida H, Ogasawara K
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-23659201
[Presentation] Identification of pandemic influenza virus NP peptides bound to cynomolgus macaque MHC class I Mafa-A1*5202 and stimulating CTL responses2011
- Author(s)
  Itoh Y, Arikata M, Maeda T, Shiina T, Ishigaki H, Takada A, Okamatsu M, Sakoda Y, Nakayama M, Kida H, Ogasawara K
- Organizer
  XV International Congress of Virology
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23659201
[Presentation] An inactivated whole particle vaccine from a non-pathogenic virus library confers protective immunity against H1N1 pandemic influenza virus more effectively than dose a split vaccine in cynomolgus macaques2010
- Author(s)
  Itoh Y, Okamatsu M, Nakayama M, Sakoda Y, Ishigaki H, Ishida H, Arikata M, Pham, VL, Soda K, Kida H, Ogasawara K
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸国際展示場 (兵庫県)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] カニクイザル MHC ホモ接合個体の特定2010
- Author(s)
  椎名隆、小笠原一誠、鳥居隆三等
- Organizer
  第19回日本組織適合性学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22300143
[Presentation] MHC全遺伝子ホモ接合体カニクイザルの特定2010
- Author(s)
  椎名隆、北夕紀、田中景子、河野あづみ、鈴木進悟、細道一善、勝山善彦、土屋英明、小田部耕二、坂本憲吾、倉田昌明、野村護、山中久、中川博司、伊藤靖、太田正穂、猪子英俊、鳥居隆三、小笠原一誠
- Organizer
  第19回日本組織適合性学会大会
- Place of Presentation
  東京大学
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-21300155
[Presentation] カニクイザルMHCホモ接合個体の特定2010
- Author(s)
  椎名隆、小笠原一誠、鳥居隆三, 等
- Organizer
  第19回日本組織適合性学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22300143
[Presentation] カニクイザルモデルを用いたパンデミック(H1N1)2009インフルエンザウイルス感染による炎症反応の解析2010
- Author(s)
  伊藤靖、石垣宏仁、仲山美沙子、小笠原一誠、河岡義裕
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  京王プラザホテル新宿(東京都)
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-22390076
[Presentation] カニクイザル3集団におけるMHCクラスI遺伝子(Mafa-A)の多型性の比較2009
- Author(s)
  北夕紀、田中景子、細道一善、小笠原一誠、鳥居隆三、猪子英俊、椎名隆
- Organizer
  第18回日本組織適合性学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-21300155
[Presentation] 子宮内膜症カニクイザル末梢血の単球およびNK細胞の動態解析
- Author(s)
  4.中村紳一朗、仲山美沙子、塚本真由美、土屋英明、野々口耕介、小笠原一誠、森崇英
- Organizer
  第36回日本エンドメトリオーシス学会
- Place of Presentation
  東京
- Year and Date
  2015-01-24 – 2015-01-25
- Data Source
  KAKENHI-PROJECT-26640054
[Presentation] Pathogenicity of pandemic (H1N1) 2009 influenza A virus in immunosuppressed cynomolgus monkeys.
- Author(s)
  Itoh Y, Nakayama M, Ishigaki H, Ogasawara K
- Organizer
  第４２回日本免疫学会総会、学術集会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-23659201

1. ONOE Kazunori (40002117)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. IWABUCHI Kazuya (20184898)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
3. ITOH Yasushi (90324566)

# of Collaborated Projects: 9 results

# of Collaborated Products: 34 results
4. ISHIGAKI Hirohito (90432301)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
5. SHHNA Takashi (00317744)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
6. TORII Ryuzo (50106647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. TSUCHIYA Hideaki (10378440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. KIDA Hiroshi (10109506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ANDO Asako (40101935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HOSOMICHI Kazuyoshi (50420948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. OTA Masao (50115333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. ITO Mutsumi (80573906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. TAKADA Ayato (10292062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. NAKAMURA Shinichiro (50307980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. TAGAWA Yoshitsugu (40109426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MATSUDA Akira (00312348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NISHIHIRA Jun (30189302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HAYASE Yoneko (40228606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. UMEMURA Takashi (00151936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SAKODA Yoshihiro (40333637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ITO Toshihiro (00176348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Fujimoto Noriki (50378460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Narita Mitsuhiro (00263046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 梶野喜一 (80322147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 佐々木えりか (70390739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 依馬正次 (60359578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 河岡義裕 (70135838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 岡崎克則 (90160663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 仲山美沙子 (00510306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
30. 七戸新太郎 (80737148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 田中俊宏 (50188314)

# of Collaborated Projects: 1 results

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32. 花田英紀 (40555067)

# of Collaborated Projects: 1 results

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33. 影山進 (50378452)

# of Collaborated Projects: 1 results

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34. 吉貴達寛 (80230704)

# of Collaborated Projects: 1 results

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35. 河内明宏 (90240952)

# of Collaborated Projects: 1 results

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36. 村井亮介 (80748583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. Takahashi Toshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. Kabuto Miho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. Tsukamoto Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. MURAMATSU Mieko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. IGARASHI Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 小原道法

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OGASAWARA Kazumasa 小笠原 一誠

小笠原 一誠 オガサワラ カズマサ

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Treatment of DSS colitis with MSCs derived from MHC-homozygous iPSCs with using cynomolgus macaquePrincipal Investigator

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Treatment by a column absorbing immunosuppressing cells in macaques with endometriosisPrincipal Investigator

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Establishment of a macaque cancer model using cancer cells derived from MHC homozygous macaque iPS cellsPrincipal Investigator

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分泌型TGF-βレセプターII遺伝子導入アデノウイルス投与による腫瘍拒絶の試みPrincipal Investigator

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リポソーム封入癌関連ペプチドと抗CD40抗体投与で誘導されるCTLの抗腫癌効果Principal Investigator

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Preparation of peptide vaccines according to the cassette theory against newly emerged influenza virusPrincipal Investigator

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OGASAWARA Kazumasa 小笠原一誠

小笠原一誠オガサワラカズマサ