YOSHIKI Tatsuhiro 吉貴達寛

… Alternative Names

Researcher Number	80230704
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2018 – 2019: 滋賀医科大学, 医学部, 客員教授 2017: 滋賀医科大学, 医学部, 准教授 2015 – 2017: 京都薬科大学, 薬学部, 教授 2012 – 2016: 滋賀医科大学, 医学部, 客員教授 2011: 京都薬科大学, 薬学部, 教授 … More
Review Section/Research Field	Principal Investigator Urology / Urology Except Principal Investigator Urology / Urology / Basic Section 56030:Urology-related
Keywords	Principal Investigator 腫瘍マーカー / 前立腺癌 / 前立腺特異抗原 / プロテオミクス / Proteomics / 遺伝子クローニング / PCR / cDNA / 前立腺 / モノクローナル抗体 … More Except Principal Investigator 尿路上皮癌 / プロテオミクス / 精巣腫瘍 / 腫瘍マーカー / γ-グルタミルシクロトランスフェラーゼ / RNA干渉 / tumor suppressor gene / カルレティキュリン / 間質性膀胱炎 / ウロプラキン / 癌治療 / 膀胱癌 / 倍数体 / X染色体 / 癌遺伝子 / 癌抑制遺伝子 / testicular cancer / gain of chromosome / X chromosome / oncogenes / 腎細胞癌 / 急速進行症例 / LOH / 膀胱尿管逆流症 / Proteomics / 低分子阻害薬 / 抗がん剤 / 精子抗原 / 精細胞 / 精子形成過程 / 自己抗体 / 非潰瘍型 / ウロプラキンデルタ4 / 分子診断 / ウロプラキンIIIデルタ4 / siRNA / GGCT / C7orf24 / 制御性T細胞 / BCG / 染色体付加 / 責任遺伝子 / マイクロサテライトマーカー / renal cell carcinoma / rapid growing / 神経因性膀胱 / 神経成長因子 / 神経栄養因子 / 分子生物学 / Neurogenic Bladder / Nerve Growth Factor / Neurotrophic Factor / Molecular Biology / 第14番染色体 / 急速進行型 / 腫瘍随伴症候群 / 不明熱 / Renal cell carcinoma / tumor suppressor gen / chromosome 14q / rapid type / paraneoplastic syndrome / メチル化 / 癌感受性遺伝子 / X染色体不活化 / 変異 / XIST / 移行上皮 / 腎盂癌 / 腎孟癌 / 移行上皮癌 / Transitional cell / Uroplakin / Tumor marker / Bladder cancer / Renal pelvic cancer / Vesicoureteral reflux / Urothelial Cancer / Tumor Marker / Calreticulin / 癌関連蛋白質 / RNA千渉 / Cancer-related protein / RNAi / Cancer treatment / ウロプラキンIII / スクリーニング検査 / 定量的PCR / vesicoureteral reflux / uroplakin III / screening / quantitative PCR / 低分子化合物 / 抗癌剤 / 細胞老化 Less

GGCT阻害分子を用いた尿路上皮癌治療の開発Ongoing
- Principal Investigator
  
  影山進
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Shiga University of Medical Science
Development of anticancer therapy for urological malignancy using GGCT inhibitors
- Principal Investigator
  
  Kageyama Susumu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Development of peptide type anti cancer drugs against a novel cell growth factor identified by ourselvesPrincipal Investigator
- Principal Investigator
  
  Yoshiki Tatsuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kyoto Pharmaceutical University
Regulatory T cells in intravesical BCG therapy for non-muscle invasive bladder cancer
- Principal Investigator
  
  Narita Mitsuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Development of anticancer therapy with GGCT targeting siRNA for urothelial tumor
- Principal Investigator
  
  KAGEYAMA Susumu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Uroplakin III-delta 4 as a new molecular marker for interstitial cystitis
- Principal Investigator
  
  KAKEHI Yoshiyuki, 植月祐次
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kagawa University
Development of urinary calreticulin test for the diagnosis of urothelial cancer
- Principal Investigator
  
  KAGEYAMA Susumu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Study of autoantibody in interstitial cystitis
- Principal Investigator
  
  NARITA Mistuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Development of anti-cancer therapy targeting U7 (C7orf24)
- Principal Investigator
  
  KAGEYAMA Susumu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Significance and development of Urine uroplakin III mRNA measurement in vesicoureteral reflux
- Principal Investigator
  
  JOHNIN Kazuyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Development of combined tumor markers identified by proteomics in urothelial cancerPrincipal Investigator
- Principal Investigator
  
  YOSHIKI Tatsuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The Department of Urology, Facultyof Medicine, Shiga University of Medical Science
Investigation for clinical usefulness of the novel urinary tumor marker, urinary calreticulin, in diagnosis for bladder cancer.
- Principal Investigator
  
  WAKABAYASHI Yoshihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Structural diversity of cancer-related and non-cancer-related prostate-specific antigenPrincipal Investigator
- Principal Investigator
  
  TATSUHIRO Yoshiki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The Department of Urology, Faculty of Medicine, Shiga University of Medical Science
Identification of gene on chromosome 14q arm responsible for the development of rapid type human renal cell carcinoma
- Principal Investigator
  
  OKAMOTO Keisei
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
IDENTIFICATION OF TESTICULAR GERM CELL TUMOR SUSCEPTIBLE GENE ON Xq27 AND INVOLVEMENT OF X INACTIVATION IN TESTICULAR GERM CELL TUMOR TUMORGENESIS
- Principal Investigator
  
  OKADA Yusaku
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Department of Urology, Faculty of Medicine, Shiga University of Medical Science
Study of human uroplakin in various diseases of urinary tract
- Principal Investigator
  
  KATAOKA Akira, 田中努
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The Department of Urology, Faculty of Medicine, Shiga University of Medical Science
Structural diversity of cancer-related and non- cancer-related prostate-apecific antigenPrincipal Investigator
- Principal Investigator
  
  YOSHIKI Tatsuhiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The Department of Urology, Faculty of Medicine, Shiga University of Medical Science
Treatment with neutrotrophic factors may prevent neurogenic bladder dysfunction
- Principal Investigator
  
  WAKABAYASHI Yoshihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
STUDY OF BIOLOGICAL IMPLICATION OF X CHROMOSOMAL GAIN IN TESTICULAR GERM CELL TUMOR
- Principal Investigator
  
  OKADA Yusaku
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
SEARCH FOR SPECIFIC GENE ALTERATIONS IN RENAL CELL CARCINOMAS WITH RAPID GROWING FEATURES
- Principal Investigator
  
  OKAMOTO Keisei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
NUCLEOTIDE SEQUENCE ANALYSES OF TRANSITIONAL CELL-SPECIFIC PROTEINS, UROPLAKINS, AND CLINICAL APPLICATIONPrincipal Investigator
- Principal Investigator
  
  YOSHIKI Tatsuhiro, 林田英資
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
上皮・間質間の作用からみたホルモン療法抵抗性前立腺癌の増殖機構に関する研究Principal Investigator
- Principal Investigator
  
  吉貴達寛
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
精細胞の分化・脱分化と精子特異抗原
- Principal Investigator
  
  友吉唯夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
精子特異抗原HSAg-5の研究Principal Investigator
- Principal Investigator
  
  吉貴達寛
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
配偶子特異抗原STX-10の一次構造と臨床的意義Principal Investigator
- Principal Investigator
  
  吉貴達寛
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
新たに同定された、前立腺上皮と神経内分泌細胞に特異的な蛋白質の一次構造解析Principal Investigator
- Principal Investigator
  
  吉貴達寛
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science

All 2018 2017 2016 2015 2014 2013 2011 2009 2007 2003 Other

All Journal Article Presentation

[Journal Article] Prohibitin-2 is a novel regulator of p21 WAF1/CIP1 induced by depletion of γ-glutamylcyclotransferase2018
- Author(s)
  Taniguchi K, Matsumura K, Kageyama S, Ii H, Ashihara E, Chano T, Kawauchi A, Yoshiki T, Nakata S.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 496 Pages: 218-224
- DOI
  10.1016/j.bbrc.2018.01.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08722, KAKENHI-PROJECT-16K11001, KAKENHI-PROJECT-15K10584, KAKENHI-PROJECT-15K10585
[Journal Article] A novel prodrug of a γ-glutamylcyclotransferase inhibitor suppresses cancer cell proliferation in vitro and inhibits tumor growth in a xenograft mouse model of prostate cancer2018
- Author(s)
  Ii H, Yoshiya T, Nakata S, Taniguchi K, Hidaka K, Tsuda S, Mochizuki M, Nishiuchi Y, Tsuda Y, Ito K, Kageyama S, Yoshiki T.
- Journal Title
  
  ChemMedChem
  
  Volume: 13 Pages: 155-163
- DOI
  10.1002/cmdc.201700660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08722, KAKENHI-PROJECT-15K10584, KAKENHI-PROJECT-15K10585
[Journal Article] Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy2018
- Author(s)
  Kageyama Susumu、Ii Hiromi、Taniguchi Keiko、Kubota Shigehisa、Yoshida Tetsuya、Isono Takahiro、Chano Tokuhiro、Yoshiya Taku、Ito Kosei、Yoshiki Tatsuhiro、Kawauchi Akihiro、Nakata Susumu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Pages: 2054-2054
- DOI
  10.3390/ijms19072054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09192, KAKENHI-PROJECT-16K08722
[Journal Article] Depletion of gamma-glutamylcyclotransferase induces autophagy prior to cellular senescence in cancer cells2018
- Author(s)
  Keiko Taniguchi, Kengo Matsumura, Susumu Nakata*, Hiromi ii, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki
- Journal Title
  
  American Journal of Cancer Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10584
[Journal Article] Design of fluorogenic probes and fluorescent-tagged inhibitors for γ-glutamyl cyclotransferase2017
- Author(s)
  Yoshiya T, Ii H, Tsuda S, Mochizuki M, Kageyama S, Yoshiki T
- Journal Title
  
  J Pept Sci.
  
  Volume: 印刷中 Pages: 618-623
- DOI
  10.1002/psc.2984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10584, KAKENHI-PROJECT-15K10585
[Journal Article] LC/QTOF-MSによるフィルグラスチムバイオ後続品の定性・成分分析2016
- Author(s)
  松村健吾, 大谷祐基, 大村友博, 米澤淳, 津田真弘, 池見泰明, 中川俊作, 今井哲司, 中川貴之, 矢野育子, 吉貴達寛, 松原和夫
- Journal Title
  
  医療薬学
  
  Volume: 42 Pages: 613-619
- NAID
  130006072835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10585
[Journal Article] Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation2016
- Author(s)
  Matsumura K, Nakata S, Taniguchi K, Ii H, Ashihara E, Kageyama S, Kawauchi A, Yoshiki T
- Journal Title
  
  BMC Cancer
  
  Volume: 16 Pages: 748-748
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10584
[Journal Article] Synthesis and GGCT Inhibitory Activity of <i>N</i>-Glutaryl-L-alanine Analogues2016
- Author(s)
  Ii H, Yoshiki T, Hoshiya N, Uenishi J
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 64 Issue: 7 Pages: 785-792
- DOI
  10.1248/cpb.c16-00167
- NAID
  130005160076
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10584, KAKENHI-PROJECT-15K10585
[Journal Article] Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, and Tatsuhiro Yoshiki.
- Journal Title
  
  BMC Cancer
  
  Volume: 48 Pages: 748-748
- DOI
  10.1186/s12885-016-2779-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461436, KAKENHI-PROJECT-15K10585, KAKENHI-PROJECT-16K08722
[Journal Article] A GGCT fluorogenic probe: design, synthesis and application to cancer-related cells2015
- Author(s)
  Yoshiya T, Ii H, Tsuda S, Kageyama S, Yoshiki T, Nishiuchi Y
- Journal Title
  
  Org Biomol Chem
  
  Volume: 13 Pages: 3182-3185
- DOI
  10.1039/c5ob00086f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592384, KAKENHI-PROJECT-15K10585
[Journal Article] Proteome research in urothelial carcinoma2015
- Author(s)
  Kageyama S, Isono T, Iwaki H, Hanada E, Tomita K, Yoshida T, Yoshiki T, Kawauchi A
- Journal Title
  
  International Journal of Urology
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592384
[Journal Article] Gamma-Glutamylcyclotransferase: A Novel Target Molecule for Cancer Diagnosis and Treatment2015
- Author(s)
  1）Susumu Kageyama, Eiki Hanada, Hiromi Ii, Keiji Tomita, Tatsuhiro Yoshiki, Akihiro Kawauchi
- Journal Title
  
  Biomed Res Int
  
  Volume: 2015 Pages: 345219-345219
- DOI
  10.1155/2015/345219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10585
[Journal Article] Proteome research in urothelial carcinoma2015
- Author(s)
  2）Susumu Kageyama, Takahiro Isono, Hideaki Iwaki, Eiki Hanada, Keiji Tomita, Tetsuya Yoshida, Tatsuhiro Yoshiki, Akihiro Kawauchi
- Journal Title
  
  Int J Urol
  
  Volume: 22 Pages: 621-628
- DOI
  10.1111/iju.12793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10585
[Journal Article] Gamma-glutamylcyclotransferase (GGCT): a novel target molecule for cancer diagnosis and treatment2015
- Author(s)
  Kageyama S, Hanada E, Ii H, Tomita K, Yoshiki T, Kawauchi A
- Journal Title
  
  BioMed Research International
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592384
[Journal Article] Upregulation of tissue and urinary uroplakin mRNA in patients with vesicoureteral reflux.2013
- Author(s)
  Iwaki H, Kageyama S, Yoshiki T
- Journal Title
  
  International Journal of Urology
  
  Volume: 21 Pages: 347-347
- DOI
  10.1111/iju.12265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592384
[Journal Article] A fluorogenic probe for γ-glutamyl cyclotransferase: application of an enzyme-triggered O-to-N acyl migration-type reaction.2013
- Author(s)
  Yoshiya T, Tsuda S, Mochizuki M, Hidaka K, Tsuda Y, Kiso Y, Kageyama S, Ii H, Yoshiki T, Nishiuchi Y
- Journal Title
  
  ChemBioChem
  
  Volume: 14 Pages: 2110-2113
- DOI
  10.1002/cbic.201300481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592384
[Journal Article] Urinary calreticulin in the diagnosis of urinary bladder urothelial carcinoma2009
- Author(s)
  Kageyama S, Isono T, Matsuda S, Ushio Y, Satomura S, Terai A, Arai Y, Kawakita M, Okada Y, Yoshiki T
- Journal Title
  
  International Journal of Urology 16
  
  Pages: 481-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591844
[Journal Article] Uroplakin III-Delta4 Messenger RNA as a Promising Marker to Identify Nonulcerative Interstitial Cystitis2007
- Author(s)
  Y Zeng, XX Wu, Y Homma, N Yoshimura, H Iwaki, S Kageyama, T Yoshiki, Y Kakehi
- Journal Title
  
  J Urol 178
  
  Pages: 1322-1327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591845
[Journal Article] 泌尿器科領域におけるブロテオミクス技術の応用2003
- Author(s)
  吉貴達寛, 景山進, 岩城秀出洙
- Journal Title
  
  泌尿器疾患の最新医療
  
  Pages: 47-54
- Data Source
  KAKENHI-PROJECT-15591681
[Presentation] 発がんマウスモデル由来膠芽腫幹細胞の増殖に対するStat5b の寄与2018
- Author(s)
  茂山千愛美, 東馬智未, 藤田貢, 安藤翔太, 岩崎仁志, 谷口恵香, 飯居宏美, 吉貴達寛, 中田晋
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] 乳癌細胞においてGGCT欠乏で誘導されるp21はprohibitin-2を介して調節される2018
- Author(s)
  29）谷口恵香，松村健吾，影山　進，飯居宏美，芦原英司，茶野徳宏，河内明宏，吉貴達寛，中田　晋
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09192
[Presentation] Gamma-glutamylcyclotransferase (GGCT) の発現低下はがん細胞にオートファジーを介して細胞老化を誘導する2018
- Author(s)
  谷口恵香, 松村健吾, 飯居宏美, 影山進, 芦原英司, 河内明宏, 吉貴達寛, 中田晋
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] 脳腫瘍幹細胞マウスモデルを用いたアセトゲニン誘導体新規がん治療薬開発2018
- Author(s)
  東馬智未, 茂山千愛美, 小島直人, 岩崎仁志, 安藤翔太, 藤田貢, 谷口恵香, 飯居宏美, 吉貴達寛, 中田晋
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-グルタミルシクロトランスフェラーゼ阻害剤の細胞老化を介した細胞増殖抑制効果と抗がん剤併用によるその効果の増強2018
- Author(s)
  高木寛子, 飯居宏美, 中田晋, 谷口恵香, 吉矢拓, 津田修吾, 望月雅允, 影山進, 吉貴達寛
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-グルタミルシクロトランスフェラーゼ阻害剤の細胞老化を介した細胞増殖抑制効果と抗がん剤併用によるその効果の増強2018
- Author(s)
  高木寛子，飯居宏美，中田　晋，谷口恵香，吉矢　拓，津田修吾，望月雅允，影山　進，吉貴達寛
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] 新規γ-グルタミルシクロトランスフェラーゼ阻害剤の抗腫瘍効果の検討2018
- Author(s)
  飯居宏美，中田　晋，谷口恵香，吉矢　拓，津田修吾，望月雅允，影山　進，吉貴達寛
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] GGCT（γ-グルタミルシクロトランスフェラーゼ）阻害を作用機序とした新規抗癌剤の開発2018
- Author(s)
  37）影山　進，窪田成寿，村井亮介，吉矢　拓，飯居宏美，中田　晋，吉貴達寛，河内明宏
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09192
[Presentation] γ-グルタミルシクロトランスフェラーゼを標的とした新規抗がん剤開発2018
- Author(s)
  28）飯居宏美，中田　晋，谷口恵香，高木寛子，茂山千愛美，影山　進，吉貴達寛
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09192
[Presentation] 新規γ-グルタミルシクロトランスフェラーゼ阻害剤の抗腫瘍効果の検討2018
- Author(s)
  飯居宏美, 中田晋, 谷口恵香, 吉矢拓, 津田修吾, 望月雅允, 影山進, 吉貴達寛
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] 担癌マウスにおけるγ-グルタミルシクロトランスフェラーゼ阻害剤の抗腫瘍効果2017
- Author(s)
  飯居宏美, 中田晋, 谷口恵香, 影山進, 吉貴達寛
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] Gamma-glutamylcyclotransferase (GGCT) の発現低下は乳癌細胞にオートファジーを誘導する2017
- Author(s)
  谷口恵香, 中田晋, 松村健吾, 飯居宏美, 影山進, 河内明宏, 吉貴達寛
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-グルタミルシクロトランスフェラーゼ(GGCT)の発現低下はオートファジーを介して細胞老化を誘導する2017
- Author(s)
  谷口恵香, 中田晋, 松村健吾, 飯居宏美, 影山進, 河内明宏, 吉貴達寛
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] Stat5b は発がんマウスモデル由来膠芽腫幹様細胞の増殖促進に寄与している2017
- Author(s)
  茂山千愛美, 藤田貢, 飯居宏美, 谷口恵香, 吉貴達寛, 中田晋
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] 担癌マウスにおけるγ-グルタミルシクロトランスフェラーゼ阻害剤の抗腫瘍効果2017
- Author(s)
  飯居宏美，中田　晋，谷口恵香，影山　進，吉貴達寛
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] γ-グルタミルシクロトランスフェラーゼ(GGCT)阻害剤のがん細胞増殖抑制機構の解析に基づくドキソルビシン併用効果に関する研究2017
- Author(s)
  高木寛子, 飯居宏美, 中田晋, 吉貴達寛
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-グルタミルシクロトランスフェラーゼ(GGCT)の発現低下はオートファジーを介して細胞老化を誘導する2017
- Author(s)
  谷口恵香，中田　晋，松村健吾，飯居宏美，影山　進，河内明宏，吉貴達寛
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] 新規癌増殖因子GGCT/C7orf24を標的とした抗がん剤の開発　-小規模プロテオーム解析からの挑戦-2017
- Author(s)
  影山　進，花田英紀，窪田成寿，富田圭司，村井亮介，小林憲市，飯居宏美，中田　晋，吉矢　拓，礒野高敬，湯浅　健，吉貴達寛，河内明宏
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] The depletion of γ -glutamylcyclotranferase induces cellular senescence and cell death via CDKIs upregulation.2017
- Author(s)
  Kengo Matsumura, Susumu Nakata, Keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki
- Organizer
  The 5th International Symposium of Training Plan for Oncology Professionals
- Place of Presentation
  シェラトン都ホテル大阪（大阪府・大阪市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] CDKI誘導を介したγ-グルタミルシクロトランスフェラーゼの抑制による細胞老化誘導2016
- Author(s)
  松村健吾，中田　晋，飯居宏美，芦原英司，影山　進，河内明宏，吉貴達寛
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth via celluar snescence caused by CDK inhibitor induction.2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki
- Organizer
  24th Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Manchester(UK)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth through cellular senescence induction2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, Keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki
- Organizer
  2016 ASCB (American Society of Cell Biology) Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] CDKI 誘導を介したγ-グルタミルシクロトランスフェラーゼの抑制による細胞老化誘導2016
- Author(s)
  松村健吾, 中田晋, 飯居宏美, 芦原英司, 影山進, 河内明宏, 吉貴達寛
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth through cellular senescence induction.2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, Keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki
- Organizer
  2016 American Society of Cell Biology (ASCB) Annual Meeting
- Place of Presentation
  San Francisco（USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-グルタミルシクロトランスフェラーゼの蛍光基質 LISA-101の開発とインヒビター探索2016
- Author(s)
  吉矢拓, 西内祐二, 飯居宏美, 中田晋, 吉貴達寛
- Organizer
  創薬懇話会2016
- Place of Presentation
  エクシブ蓼科（長野県・茅野市）
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] Depletion of γ-glutamylcyclotransferase inhibits cancer cell growth via celluar snescence caused by CDK inhibitor induction2016
- Author(s)
  Kengo Matsumura, Susumu Nakata, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi, Tatsuhiro Yoshiki
- Organizer
  24th Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Manchester, UK
- Year and Date
  2016-07-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] γ-Glutamyl cyclotransferase(GGCT)強制発現細胞を用いたGGCT阻害剤による細胞増殖抑制効果の検討2016
- Author(s)
  青木沙織, 宇野加奈恵, 吉矢拓, 西内祐二, 飯居宏美, 中田晋, 吉貴達寛
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] プロテオーム解析による尿路上皮癌治療標的の探索2015
- Author(s)
  影山　進，花田英紀，富田圭司，村井亮介，小林憲市，吉田哲也，吉貴達寛，河内明宏
- Organizer
  第42回京阪泌尿器腫瘍セミナー
- Place of Presentation
  メルパルク京都
- Year and Date
  2015-02-09
- Data Source
  KAKENHI-PROJECT-24592384
[Presentation] γ-グルタミルシクロトランスフェラーゼ：蛍光基質LISA-101の開発とインヒビター探索2015
- Author(s)
  吉矢拓, 飯居宏美, 津田修吾, 影山進, 吉貴達寛, 西内祐二
- Organizer
  第20回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-グルタミルシクロトランスフェラーゼ（GGCT）基質"LISA101"の開発と応用2015
- Author(s)
  吉矢拓, 飯居宏美, 津田修吾, 影山進, 吉貴達寛, 西内祐二
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] 乳がん細胞株MCF-7細胞におけるγ-glutamyl cyclotransferase阻害によるオートファジー誘導の検討2015
- Author(s)
  塩見紗英子, 飯居宏美, 中田晋, 吉貴達寛
- Organizer
  第65回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府富田林市
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ-Glutamyl cyclotransferase阻害によるアポトーシス非依存的細胞増殖抑制2015
- Author(s)
  佐原真美, 澤野友紀, 飯居宏美, 中田晋, 吉貴達寛
- Organizer
  第65回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府富田林市
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] γ－グルタミルシクロトランスフェラーゼ：蛍光基質 LISA-101の開発とインヒビター探索2015
- Author(s)
  吉矢拓、飯居宏美、津田修吾、影山進、吉貴達寛、西内祐二
- Organizer
  第20回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] γ-グルタミルシクロトランスフェラーゼ (GGCT) 基質 "LISA-101" の開発と応用2015
- Author(s)
  吉矢拓、飯居宏美、津田修吾、影山進、吉貴達寛、西内祐二
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K10584
[Presentation] 新規γ-glutamylcyclotransferase (GGCT)阻害剤の探索とその膜透過型プロドラッグ開発2015
- Author(s)
  飯居宏美, 谷口恵香, 中田晋, 吉貴達寛
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K10585
[Presentation] 新規癌関連タンパク質C7orf24を標的とした去勢抵抗性前立腺癌治療の開発2014
- Author(s)
  花田英紀，影山　進，荒木勇雄，河内明宏，飯居宏美，吉貴達寛
- Organizer
  第102回日本泌尿器科学会総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24592384
[Presentation] C7orf24阻害による新規細胞死機構の検討2014
- Author(s)
  飯居宏美，狩野　智，花田英紀，影山　進，吉貴達寛
- Organizer
  第64回日本薬学会近畿支部
- Place of Presentation
  京都薬科大学
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24592384
[Presentation] 間質性膀胱炎患者膀胱上皮および尿中剥離細胞におけるウロプラキンIII-delta4の発現2011
- Author(s)
  筧善行, 張霞, 平間裕美, 加藤琢磨, 本間之夫, 大橋洋三, 影山進, 吉貴達寛
- Organizer
  第18回日本排尿機能学会
- Place of Presentation
  福井市
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21592074
[Presentation] 新規癌関連タンパク質C7orf24を標的とした去勢抵抗性前立腺癌治療の開発
- Author(s)
  花田英紀，影山　進，荒木勇雄，河内明宏，飯居宏美，吉貴達寛
- Organizer
  第102回日本泌尿器科学会総会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24592384

1. KIM Chul Jang (10204968)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
2. KAGEYAMA Susumu (50378452)

# of Collaborated Projects: 9 results

# of Collaborated Products: 45 results
3. JOHNIN Kazuyoshi (90324590)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
4. NARITA Mistuhiro (00263046)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. KATAOKA Akira (80293835)

# of Collaborated Projects: 6 results

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6. OKAMOTO Keisei (50303780)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. WAKABAYASHI Yoshihiko (80191724)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. OKADA Yusaku (20127062)

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9. HAYASHIDA Hideshi (20173049)

# of Collaborated Projects: 4 results

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10. HANADA Eiki (40555067)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
11. KAWAUCHI Akihiro (90240952)

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# of Collaborated Products: 16 results
12. 濱口晃一 (30242986)

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# of Collaborated Products: 0 results
13. 友吉唯夫 (20025547)

# of Collaborated Projects: 2 results

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14. 村井亮介 (80748583)

# of Collaborated Projects: 2 results

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15. 坂野祐司 (00346016)

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16. 富田圭司 (30640148)

# of Collaborated Projects: 2 results

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17. 吉田哲也 (60510310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
18. USHIDA Hiroshi (80418756)

# of Collaborated Projects: 1 results

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19. KAKEHI Yoshiyuki (20214273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. TYOU Ka (30524061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. WU Xiu-xian (10346645)

# of Collaborated Projects: 1 results

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22. INUI Masashi (40314918)

# of Collaborated Projects: 1 results

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23. SUGIMOTO Mikio (10243768)

# of Collaborated Projects: 1 results

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24. HONMA Yukio (40165626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. ARAKI Isao (50252424)

# of Collaborated Projects: 1 results

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26. OGASAWARA Kazumasa (20169163)

# of Collaborated Projects: 1 results

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27. MAKIURA Yaeko (90293836)

# of Collaborated Projects: 1 results

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28. ARAIA Yutaka (90151141)

# of Collaborated Projects: 1 results

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29. OGAWA Osamu (90260611)

# of Collaborated Projects: 1 results

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30. SUGIHARA Hiroyuki (30171169)

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31. 上田正道 (50115797)

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33. 常森寛行 (20380173)

# of Collaborated Projects: 1 results

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34. 田中努 (00324583)

# of Collaborated Projects: 1 results

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35. 平竹潤 (80199075)

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36. 茶野徳宏 (40346028)

# of Collaborated Projects: 1 results

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37. 中田晋

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
38. 芦原英司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIKI Tatsuhiro 吉貴 達寛

吉貴 達寛 ヨシキ タツヒロ

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GGCT阻害分子を用いた尿路上皮癌治療の開発Ongoing

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Development of peptide type anti cancer drugs against a novel cell growth factor identified by ourselvesPrincipal Investigator

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Development of combined tumor markers identified by proteomics in urothelial cancerPrincipal Investigator

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Structural diversity of cancer-related and non-cancer-related prostate-specific antigenPrincipal Investigator

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YOSHIKI Tatsuhiro 吉貴達寛

吉貴達寛ヨシキタツヒロ