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Furuya Sonoko  古家 園子

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… Alternative Names

FURUYA Sonoko  古家 園子

古屋 園子  フルヤ ソノコ

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Researcher Number 20096952
Other IDs
Affiliation (Current) 2025: 生理学研究所, 脳機能計測・支援センター, 特別協力研究員
Affiliation (based on the past Project Information) *help 2014: 生理学研究所・個別研究, 村上正隆, 特別協力研究員
2012 – 2014: 生理学研究所, 個別研究 村上正隆, 特別協力研究員
2004 – 2006: 自然科学研究機構, 生理学研究所, 助手
2004: 名古屋大学, 自然科学研究機構・生理学研究所, 助手
2004: National Institute for Physiological Sciences, Center for Brain Experiment, Research Associate, 脳機能計測センター, 助手 … More
1999 – 2003: National Institute for Physiologocal Sciences, research associate, 生理学研究所, 助手
1996: National Institute for Physiological Sciences, 生理学研究所, 助手
1990 – 1996: 岡崎国立共同研究機構, 生理学研究所, 助手
1994: 岡崎国立共同研究機構, 整理学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) / Nerve anatomy/Neuropathology
Except Principal Investigator
Gastroenterology / Gastroenterology / General physiology / Biological Sciences
Keywords
Principal Investigator
小腸 / ギャップ結合 / アストロサイト / ATP / IP3 / 免疫組織化学 / 筋線維芽細胞 / small intestine / 筋繊維芽細胞 / Fura-2 … More / ビメンチン / Furaー2 / エンドセリン / mechanical stimulation / mechano-sensor / Ca2+ signaling / epithelial cells / T84 cells / subepithelial fibroblasts / 神経 / RT-PCR / 水チャネル / 機械的刺激 / メカノセンサー / 細胞間Ca^<2+>シグナリング / 上皮細胞 / T84細胞 / 絨毛上皮下線維芽細胞 / Freeze fracture / immunohistochemistry / ATP receptor / Ca^<2+> wave / subepithelial fibroblast / Gap junction / IP3受容体 / 蛍光免疫組織化学 / cAMP / 小腸繊毛下線維芽細胞 / フリーズフラクチャー / ATP受容体 / Ca^<2+>波の伝播 / 小腸絨毛下線維芽細胞 / 脳 / GFAP / モノクローナル抗体 / interstitial cell / Ca / cyclic-AMP / actin / endothelin / astrocytes / fibroblasts / セロトニン / ジブチリルサイクリックAMP / カルシウムイオン / サイクリックAMP / アクチン / 線維芽細胞 / Myenteric Plexus / 大腸 / ICs細胞 / ヒルシュスプラング病 / エンドセリンB受容体 / 電顕オ-トラジオグラフィ- / 肺胞 / 腎糸球体 / 毛細血管内皮細胞 … More
Except Principal Investigator
CFTR / 膵導管細胞 / PACAP / 単離小葉間膵管 / pancreatic duct cell / VIP / 5-hydroxytriptamine / HCO_3^-分泌 / aquaporin / 慢性膵炎 / 水チャネル / 免疫組織化学 / グアニリン / fibrocystin / chronic pancreatitis / TG repeat / バゾプレッシン / プリン受容体 / マイクロパーフュージョン / guanylin / NMRスペクトル / PRP / NMR spectroscopy / エンドセリン / 構造活性相関 / 細胞内Cl^-濃度 / Na^+-HCO_3^-共輸送体 / 嚢胞線維症 / SLC26 / HCO_3^-輸送 / 水輸送 / 腎臓 / 消化管 / オートラジオグラフィー / 受容体 / プログアニリン / cystic fibrosis / SLC26 transporters / Na^+-H^+ exchange (NHE) / HCO_3- transport / water tranport / センサー分子 / 遺伝子多型 / RNAi / 遺伝子変異 / 嚢胞性線維症 / SLC26輸送担体 / Na^+-H^+交換(NHE) / SLC26 transporter / HCO_3^- secretion / poly T / sweat chloride concentration / 水分泌測定 / 単離導管細胞 / トランスジュニックマウス / ポリT多型 / CFTR遺伝子異常 / CFTRクロライドチャンネル / Na^+-HCO_3^-cotransport / Cl^--HCO_3^-交換 / 細胞内電位 / 膵HCO_3^-輸送 / SLC26蛋白 / ポリT配列 / 汗中Cl^-濃度 / alcoholic chronic pancreatitis / fluid hypersecretion / ethanol / enterochromaffm cell / bicarbonate transport / Ca^<2+>オシレーション / PLA_2 / 単離膵導管細胞 / HCO_3^-交換輸送体 / Cl^- / HCO_3^-透過性 / 細胞内pH測定 / マイクロパーフュジョン / Na^+-HCO_3^- cotransport / 細胞内C1^-濃度 / アルコール性慢性膵炎 / 過分泌 / エタノール / EC細胞 / 重炭酸イオン輸送 / phospholipase AィイD22ィエD2 / pancreatic blood flow / arginine vasopressin / purinoceptors / HCOィイD23ィエD2ィイD1-ィエD1 secretion / 膵血流 / イオン輸送 / 重炭酸イオン / Ca^<++>オシレーション / PLA2 / 単離水腺房細胞 / 膵腺房細胞 / phospholipaseA2 / アクアポリン / 管腔内微量灌流法 / HCO^-_3分泌 / autoradiography / molecular structure / radioreceptor assay / kidney / gastrointestinal tract / immunohistochemistry / proguanylin / エンテロクロマフィン細胞 / 消化管粘膜 / 特異抗体 / 異性体 / エンテロトキシン / (8)オートラジオグラフィー / (7)分子構造 / (6)ラジオレセプターアッセイ / (5)腎臓 / (4)消化管 / (3)免疫組織化学 / (2)プログアニリン / (1)グアニリン / 分子構造 / ラジオレセプターアッセイ / radioimmunoassay / receptor / secretin / endothelin / セクレチン / ラジオイムノアッセイ / NMRスペクトル分析 / physiological function / structure-activity relationship / vasodilator / peptide synthesis / peptide structure / 心房ペプチド / イオン交換HPLCカラム / オ-トラジオグラフィ- / 二次元NMR / ペプチドの構造決定 / 生理作用 / 脈管拡張物質 / NMRスペクトルスコピー / ペプチドの化学合成 / ペプチドの構造 / Primary cilia / 多発性嚢胞腎症 / primary cilia / 膵管 / Na^+HCO_3^-cotransport / 細胞内小胞 / AQP1 / 水透過性 / 小葉内膵管 / 介在部導管 / 内分泌 Less
  • Research Projects

    (16 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (32 People)
  •  A study of molecular pathogenesis of chronic pancreatitis by using polycystic kidney rat

    • Principal Investigator
      ISHIGURO Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Molecular pathogenesis of chronic pancreatitis: CFTR and intraductal sensor molecules

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Signal transduction from subepithelial fibroblasts to absorptive epithelial cells in the rat small intestine.Principal Investigator

    • Principal Investigator
      FURUYA Sonoko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      National Institute for Physiological Science
      Okazaki National Research Institutes
  •  消化管における水チャネル機能と水輸送のダイナミックス

    • Principal Investigator
      成瀬 達
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Roles of CFTR chloride channel in the pathogenesis of chronic pancreatitis

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Molecular mechanisms of chronic pancreatitis : Ethanol-induced dysfunction of ion channels

    • Principal Investigator
      HAYAKAWA Tetsuo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Ca^<2+> signaling in the subepithelial fibroblasts of small intestinePrincipal Investigator

    • Principal Investigator
      FURUYA Sonoko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      National Institute for Phy siological Sciences
  •  Molecular mechanisms of ion transport and clinical application

    • Principal Investigator
      HAYAKAWA Tetsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General physiology
    • Research Institution
      Nagoya University
  •  エンドセリンB受容体を持つ腸管筋層間線維芽細胞様介在細胞の機能とネットワーク構築Principal Investigator

    • Principal Investigator
      古家 園子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Okazaki National Research Institutes
  •  グアニリン産生細胞の免疫学的、分子生物学的同定とその生理作用の研究

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  グアニリンの分子構造、細胞学、生理学とその臨床応用

    • Principal Investigator
      HAYAKAWA Tetsuo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  Molecular recognition of vasoactive peptides : basis for Physiological action

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  脳アストロサイトと腸管筋線維芽細胞の免疫学的類似性-Principal Investigator

    • Principal Investigator
      古家 園子
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Okazaki National Research Institutes
  •  エンドセリン受容体を持つ毛細血管内皮細胞の構造と機能Principal Investigator

    • Principal Investigator
      古家 園子
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Structure and function of fibroblasts which have endothelin receptorsPrincipal Investigator

    • Principal Investigator
      FURUYA Sonoko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Okazaki National Research Institute
  •  Biosyntesis and Physiological action of vasoactive peptides

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okazaki National Research Institutes

All 2012 2005 2004 Other

All Journal Article

  • [Journal Article] Structure and function of the pancreas in the polycystic kidney rat2012

    • Author(s)
      Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H
    • Journal Title

      Pancreas

      Volume: (in press) Issue: 8 Pages: 1292-8

    • DOI

      10.1097/mpa.0b013e31824c12f9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-24591010
  • [Journal Article] Characteristics of cultured subepithelial fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005

    • Author(s)
      Furuya S, Furuya K, T, Sokabe, Hirose T, Ozaki T
    • Journal Title

      Cell and Tissue Research 319

      Pages: 113-119

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Characteristics of subepithelial fibroblasts as a mechano-sensor in the intestine : Cell-shape dependent ATP release and P2Y1 signaling.2005

    • Author(s)
      Furuya K, Sokabe M, Furuya S
    • Journal Title

      J Cell Science (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Characteristics of cultured subepithelia fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005

    • Author(s)
      Furuya S, Furuya K, T, Sokabe, Hiroe T, Ozaki T
    • Journal Title

      Cell and Tissue Researc 319

      Pages: 113-119

    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Characteristics of cultured subepithelial fibroblasts in the rat small Intestine. II Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005

    • Author(s)
      Furuya S, Furuya K, Sokabe M, Hiroe T, Ozaki T
    • Journal Title

      Cell Tissue Research 319

      Pages: 113-119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts as a mechanosensor in rat intestinal villi.2004

    • Author(s)
      Furuya S, Furuya K, Sokabe M.
    • Journal Title

      Anatomical Science International 79 Suppl 413

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts as a mechanosensor in rat intestinal villi.2004

    • Author(s)
      Furuya S, Furuya K, Sokabe M
    • Journal Title

      Anatomical Science International 79 Suppl

      Pages: 413-413

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts work as a mechano-sensor in the intestine.2004

    • Author(s)
      Furuya K, Furuya S, Sokabe M.
    • Journal Title

      Japanese Jornal of Physiology 34

    • NAID

      130005447436

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts work as a mechano-sensor in the intestine.2004

    • Author(s)
      Furuya S, Furuya K, Sokabe M
    • Journal Title

      Japanese Journal of Physiology 34

    • NAID

      130005447436

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Charactaristics of subepithelial fibroblasts as a mechano-sensor in the intestine: Cell-shape dependent ATP release and P2Y1 signaling.

    • Author(s)
      Furuya K, Sokabe M, Furuya S
    • Journal Title

      J Cell Science (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • 1.  NARUSE Satoru (50180550)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  ISHIGURO Hiroshi (90303651)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  KITAGAWA Motoji (80262898)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  WARY Victor
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  FURUYA Kishio (40132740)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  OZAKI Tsutosi (20045694)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  NOKIHARA Kiyoshi (60137073)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  HAYAKAWA Tetsuo (80022838)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  NAGAHAMA Masato (50198355)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  NAGAO Shizuko (20183527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  FORSSMANN W.g.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  VICTOR WRAY
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  HERBST F.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  FORSSMANN W.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  NAKAKUKI MIyuki (30578729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YAMAMOTO Akiko (60402385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  KUWAHARA Atsukazu (60142890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SEO Yositeru (90179317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KOBAYASHI Shigeru (00018342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KONDO Takaharu (20135388)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  中山 孝 (90150060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  CETIN Yalcin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TSUJI Shigeru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  F. HERBST
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  W.G. FORSSMA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  HERBST Franz
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  FORSSMNN W.G
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KLAUS Werner
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  TSUJI Shige
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  KIFFE michae
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  丸中 良典
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  CASE R.M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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