KUWAHARA ATSUKAZU 桑原厚和

… Alternative Names

桑原厚和クワハラアツカズ

Kuwahara Atsukazu 桑原厚和

KUWAHARA Atsukazu 桑原厚和

KUWAHARA Atukazu 桑原厚和

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Researcher Number	60142890
Other IDs
Affiliation (Current)	2023: 山形大学, 地域教育文化学部, 客員研究員
Affiliation (based on the past Project Information) *help	2021: 立命館大学, 総合科学技術研究機構, 教授 2020: 立命館大学, 総合科学技術研究機構, 客員教授 2017: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授 2015 – 2016: 静岡県立大学, 食品栄養科学部, 教授 2011: 静岡県立大学, 大学院・環境科学研究所, 教授 … More 2009 – 2011: University of Shizuoka, 環境科学研究所, 教授 2006 – 2007: 静岡県立大学, 環境科学研究所, 教授 1999 – 2001: 静岡県立大学, 環境科学研究所, 助教授 1996 – 1997: Univ. of Shizuoka, 大学院, 助教授 1996: 静岡県立大学, 大学院・生活健康科学研究科, 助教授 1994: National Institute for Physiological Sciences, 生理学研究所, 助手 1990 – 1994: 岡崎国立共同研究機構, 生理学研究所, 助手 1992: National Institute of Physiological Sciences, Research Associate, 助手 1991: 岡崎共同研究機構, 助手 1991: 岡崎国立共同研究機構研究所, 生理学, 助手 Less
Review Section/Research Field	Principal Investigator General physiology / General physiology / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator General anatomy (including Histology/Embryology)
Keywords	Principal Investigator イオン輸送 / Ion transport / 大腸 / クロライド分泌 / モルモット / VIP / 消化管 / Guinea-pig / 腸管神経叢 / 短鎖脂肪酸受容体 … More / 食物繊維 / 粘膜上皮 / Distal colon / Chloride secretion / Tachykinin / Crypt cell / Cytosolic free calcium / Conforcal micorscopy / 5-HT3 receptor / Rat / 腸内分泌細胞 / PACAP / 壁内神経叢 / 神経伝達物質 / 化学受容細胞 / L型腸内分泌細胞 / プロスタグランジン / 苦味受容体 / 匂い受容体 / TRPA1チャネル / 神経ペプチド / 受容体 / 壁内神経 / enteric nervous system / ion transport / neuropeptide / chloride / secretion / colon / gastrointestinal tract / receptor / guinea-pig / Cytosolic Calcium / Conforcal microscopy / Distal Colon / Chloride Secretion / Crypt Cell / Ion Transport / Guinea - pig / Gastrointestinal tract / 5-HT 3 receptor / 5-HT_3 receptor / Gastrointestinal Tract / GPCR受容体 / 大腸機能 / 腸管運動 / 化学受容 / 大腸運動 / short chain fatty acid / G protein coupled receptor / colonic function / inn transnnrt / dietary fiber / intestinal motility / chemosensory / epithelium / chemosensory cell / enteroendocrine cell / epithelial ion transport / enteric nervous ssytem / brain-gut axis / 脳腸相関 / 散在性化学物質受容機構 / エネルギー制御 / 腸内細菌 / 恒常性維持機構 / 高次脳機能 / メタボリックシンドローム / 散在性化学受容機構 / ネルギー制御 / 化学物質受容 / 腸管神経系 / 脳腸ペプチド / 胆汁酸 / 胆汁酸受容体 / TGR5 / インクレチン / ホルモン / 消化管粘膜上皮 / 肥満 … More Except Principal Investigator VIP / PACAP / ガラニン / Galanin / Helodermin / ラット / 食道 / 横紋筋線維 / ガラニン含有神経 / ACh / CGRP運動神経 / 神経筋シナプス / 二重神経支配 / 抑制性 / 壁内神経 / 外来性自律神経 / 骨盤神経 / 迷走神経 / アウエルバッハ神経叢 / 直腸,下行結腸 / 胃 / FastーEPSPs / アウェルバッハ壁内神経 / ルシファ-イエロ- / 胃壁神経 / 下行結腸 / Yペプチド / 直腸 / C線維 / enteric nervous system / myenteric plexus / autonomic nervous system / morphology vagus nerve / pelvic nerve / C fiber / ペプチドの構造 / ペプチドの化学合成 / NMRスペクトルスコピー / 脈管拡張物質 / 構造活性相関 / 生理作用 / ペプチドの構造決定 / 二次元NMR / エンドセリン / オ-トラジオグラフィ- / イオン交換HPLCカラム / 心房ペプチド / peptide structure / peptide synthesis / NMR spectroscopy / vasodilator / structure-activity relationship / physiological function / P物質 / ガラニン(1-15) / 受容体 / ガラニンアゴニスト / ガラニン(1-15)受容体 / ガラニンアンタゴニスト / [D-Thr^6,D-Trp^<8,9>]-galanin(1-15)-ol / ガラニン・アゴニスト / ガラニン・アンタゴニスト / 合成ペプチド / 化学合成 / ガラニン作用 / 特異抗体 / Substance P / Galanin (1-15) / Receptor / (D-Thr^6,D-Trp^<8,9>)-galanin (1-15)-ol / Galanin (1-15) receptor / Galanin agonist / Galanin antagonist / 腸クロム親和細胞 / セロトニン / 下痢 / 傍分泌 / Enterochromaffin cell / Serotonin / Diarrhea / Paracrine secretion / セレクチン前駆体 / CCK受容体 / [D-Trp^8]galanin(1-15)ol / 漢方生薬 / Secretin precursor / CCK receptor / [D-Trp^8] galanin (1-15) ol / Chinese herb Less

消化管粘膜上皮化学物質受容機構を介した肥満等代謝性疾患予防に関する研究Principal Investigator
- Principal Investigator
  
  桑原厚和
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Ritsumeikan University
Involvement of Chemosensory System on Intestinal Epithelial FunctionPrincipal Investigator
- Principal Investigator
  
  Kuwahara Atsukazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
  University of Shizuoka
Studies on the mechanism of epithelial ion transport mediated by Chemical receptors expressed in the colonic mucosaPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Atsukazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  University of Shizuoka
Regulation of ion transpot by short chain fatty acids receptor, GPR43 in colonic epitheliaPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Atsukazu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  University of Shizuoka
Molecular Physiology of neurotransmitters, VIP and 5-HT in the Gastrointestinal TractPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Atukazu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  University of Shizuoka
食道横紋筋を支配するガラニン含有神経の機能的役割
- Principal Investigator
  
  藏本博史
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto Institute of Technology
Analysis of the intracellular second messenger pathway in the intestinal epithelial cellPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Atsukazu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General physiology
- Research Institution
  University of Shizuoka
消化管粘膜イオン輸送制御機構における伝達物質の放出動態に関する研究Principal Investigator
- Principal Investigator
  
  桑原厚和
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes
The role of neuropeptide reseptor and its antagonists
- Principal Investigator
  
  YANAIHARA Noboru
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Shizuoka
新規生理活性物質、PACAPによる消化管粘膜イオン輸送調節機構に関する研究Principal Investigator
- Principal Investigator
  
  桑原厚和
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Okazaki National Research Institutes
Regulation of water and electrolyte transport in the gutPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Atsukazu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  National Institute for Physiological Sciences, Okazaki National Research Institutes
Involvement of enterochromaffin (EC) cells in diarrhea
- Principal Investigator
  
  FUJITA Tsuneo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Niigata University
Joint study on design, synthesis and analysis of agonists and antagonists of galanin
- Principal Investigator
  
  YANAIHARA Noboru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Shizuoka
Mechanism of nervous interaction between the enteric nervous system and the autonomic nervous system
- Principal Investigator
  
  TAMURA Kenji
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tokai University
Biosyntesis and Physiological action of vasoactive peptides
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Okazaki National Research Institutes

[Book] 腸管上皮における管腔内化学物質受容体が腸管機能に与える影響Luminal chemosensing and colonic ion transport2011
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Total Pages
  60
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21590235
[Book] 腸管上皮における管腔内化学物質受容体が腸管機能に与える影響2011
- Author(s)
  加治いずみ、唐木晋一郎、桑原厚和
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21590235
[Book] 消化管の管腔内化学受容と消化管機能制御.消化管の栄養・生理と腸内細菌(Hindgut Club Japan編)2011
- Author(s)
  唐木晋一郎, 桑原厚和
- Total Pages
  328
- Publisher
  アニマル・メディア社
- Data Source
  KAKENHI-PROJECT-21590235
[Book] 消化管の管腔内化学受容と消化管機能制御2011
- Author(s)
  唐木晋一郎, 桑原厚和
- Publisher
  アニマル・メディア
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Minimum biological domain of xenin-25 required to induce anion secretion in the rat ileum2022
- Author(s)
  Kuwahara Yuko、Takahashi Kohei、Akai Miho、Kato Ikuo、Kozakai Takaharu、Asano Shinji、Inui Toshio、Marunaka Yoshinori、Kuwahara Atsukazu
- Journal Title
  
  Peptides
  
  Volume: 147 Pages: 170680-170680
- DOI
  10.1016/j.peptides.2021.170680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03368, KAKENHI-PROJECT-20K11544
[Journal Article] The effect of Xenin25 on spontaneous circular muscle contractions of rat distal colon in vitro2021
- Author(s)
  Kuwahara Yuko、Kato Ikuo、Inui Toshio、Marunaka Yoshinori、Kuwahara Atsukazu
- Journal Title
  
  Physiol Rep
  
  Volume: 9 Pages: 1-14
- DOI
  10.14814/phy2.14752
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11544, KAKENHI-PROJECT-18H03182
[Journal Article] GLP-2 Acutely Prevents Endotoxin-Related Increased Intestinal Paracellular Permeability in Rats2020
- Author(s)
  Maruta Koji、Takajo Takeshi、Akiba Yasutada、Said Hyder、Irie Emi、Kato Ikuo、Kuwahara Atsukazu、Kaunitz Jonathan D.
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 65 Pages: 2605-2618
- DOI
  10.1007/s10620-020-06097-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11544
[Journal Article] Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system2020
- Author(s)
  KUWAHARA Atsukazu、MATSUDA Kyoko、KUWAHARA Yuko、ASANO Shinji、INUI Toshio、MARUNAKA Yoshinori
- Journal Title
  
  Biomedical Research
  
  Volume: 41 Issue: 5 Pages: 199-216
- DOI
  10.2220/biomedres.41.199
- NAID
  130007927037
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11544, KAKENHI-PROJECT-18H03182
[Journal Article] The effects of intra-stomach obestatin administration on intestinal contractility in neonatal piglets fed milk formula2020
- Author(s)
  Slupecka-Ziemilska Monika、Szczurek Paulina、Boryczka Maria、Gajewska Malgorzata、Wychowanski Piotr、Kuwahara Atsukazu、Kato Ikuo、Dziegelewska Zaneta、Wolinski Jaroslaw
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Pages: 1-13
- DOI
  10.1371/journal.pone.0230190
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11544
[Journal Article] Influence of obestatin on the histological development of the small intestine in piglets during the first week of postnatal life2020
- Author(s)
  Wolinski J.、Szczurek P.、Pierzynowska K.、Wychowanski P.、Seklecka B.、Boryczka M.、Kuwahara A.、Kato I.、Drahanchuk O.、Zaworski K.、Pierzynowski S.G.、Slupecka-Ziemilska M.
- Journal Title
  
  Animal
  
  Volume: 14 Pages: 2129-2137
- DOI
  10.1017/s1751731120000919
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11544
[Journal Article] Lipopolysaccharides transport during fat absorption in rodent small intestine2020
- Author(s)
  Akiba Yasutada、Maruta Koji、Takajo Takeshi、Narimatsu Kazuyuki、Said Hyder、Kato Ikuo、Kuwahara Atsukazu、Kaunitz Jonathan D.
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology
  
  Volume: 318
- DOI
  10.1152/ajpgi.00079.2020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11544
[Journal Article] Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon2018
- Author(s)
  Kaji I, Akiba Y, Furuyama T, Adelson DW, Iwamoto K, Watanabe M, Kuwahara A, Kaunitz JD
- Journal Title
  
  Neurogastroenterology & Motility
  
  Volume: 30(1) Pages: 1-12
- DOI
  10.1111/nmo.13157
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Regulation of ion transport in the intestine by free fatty acid receptor 2 and 3: Possible involvement of the diffuse chemosensory system2018
- Author(s)
  Kuwahara A, Kuwahara Y, Inui T, Marunaka Y
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 19(3)
- DOI
  10.3390/ijms19030735
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] FFA2 activation combined with ulcerogenic COX inhibition induces duodenal mucosal injury via the 5-HT pathway in rats2017
- Author(s)
  Akiba Y, Maruta K, Narimatsu K, Said H, Kaji I, Kuri A, Iwamoto KI, Kuwahara A, Kaunitz JD
- Journal Title
  
  American Journal of Physiology
  
  Volume: 313(2)
- DOI
  10.1152/ajpgi.00041.2017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Xenin augments duodenal anion secretion via activation of afferent neural pathways2017
- Author(s)
  Kaji I, Akiba Y, Kato I, Maruta K, Kuwahara A, Kaunitz JD
- Journal Title
  
  Journal of Pharmacology & Experimentel Therapeutics
  
  Volume: 361 Pages: 151-161
- DOI
  10.1124/jpet.116.238485
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] The influence of enteral obestatin administration to suckling rats on intestinal contractility2017
- Author(s)
  Slupecka M, Grzesiak P, Kwiatkowski J, Gajewska M, Kuwahara A, kato I, Wolinski J
- Journal Title
  
  General comparative Endocrinology
  
  Volume: 11 Pages: 360-368
- DOI
  10.1016/j.ygcen.2017.02.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] FFA3 activation stimulates duodenal bicarbonate secretion and prevents NSAID-induced enteropathy via the GLP-2 pathway in rats.2017
- Author(s)
  Said H, Akiba Y, Narimatsu K, Maruta K, Kuri A, Iwamoto, KI, Kuwahara A, Kaunitz JD
- Journal Title
  
  Digestive Disease & Sciences
  
  Volume: 62(8) Pages: 1944-1952
- DOI
  10.1007/s10620-017-4600-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Activation of muscarinic receptors prevents TNF-a - mediated intestinal epithelial barrier disruption through p38 MAPK.2017
- Author(s)
  Uwada Junsuke、Yazawa Takashi、Islam Md Tariqul、Khan Md Rafiqul Islam、Krug Susanne M.、Fromm Michael、Karaki Shin-ichiro、Suzuki Yuichi、Kuwahara Atsukazu、Yoshiki Hatsumi、Sada Kiyonao、Muramatsu Ikunobu、Taniguchi Takanobu
- Journal Title
  
  Cellular Signaling
  
  Volume: 35 Pages: 188-196
- DOI
  10.1016/j.cellsig.2017.04.007
- NAID
  120006491645
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08656, KAKENHI-PROJECT-16K19012, KAKENHI-PROJECT-15K08182, KAKENHI-PROJECT-15K08250, KAKENHI-PROJECT-15K10654
[Journal Article] Diversity of the intestinal microbiota differently affects non-neural and atropine-sensitive ileal contractile responses to short-chain fatty acids in mice2016
- Author(s)
  Yajima M, Karaki SI, Tsuruta T, Kimura S, Nio-Kobayashi J, Kuwahara A, Yajima T.
- Journal Title
  
  Biomedical Research
  
  Volume: 37 Pages: 319-328
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Effects of e-viniferin, a dehydrodimer of resverarol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa2016
- Author(s)
  Karaki S, Ishikawa J, Tomizawa Y, Kuwahara A
- Journal Title
  
  Physiological Report
  
  Volume: 4
- DOI
  10.14814/phy2.12790
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870487, KAKENHI-PROJECT-15K08182
[Journal Article] Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon,2016
- Author(s)
  Kaji, I.;Akiba, Y.;Konno, K.;Watanabe, M.;Kimura, S.;Iwanaga, T.;Kuri, A.;Iwamoto, K. I.;Kuwahara, A.;Kaunitz, J. D.
- Journal Title
  
  Journal of Physiology
  
  Volume: － Pages: 3339-3352
- DOI
  10.1113/jp271441
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-15K08182
[Journal Article] The role of apelin in the modulation of gastric and pancreatic enzymes activity in adult rats2016
- Author(s)
  Antuschevich H, Kapica M, Krawczynska A, Herman A, Kato I, Kuwahara A, Zabielski R.
- Journal Title
  
  Journal of Physiology & Pharmacology
  
  Volume: 67 Pages: 403-409
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Apelin's efects on young rat gastrointestinal tract maturation2015
- Author(s)
  Antushevich H, Bierla J, Pawlina B, Kapica M, Krawczynska A, Herman AP, Kato I, Kuwahara A and Zabielski R
- Journal Title
  
  Peptides
  
  Volume: 65 Pages: 1-5
- DOI
  10.1016/j.peptides.2014.11.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Activation of muscarinic cholinoceptor ameliorates tumor necrosis factor-α-induced barrier dysfunction in intestinal epithelial cells2015
- Author(s)
  Khan MR, Uwada J, Yazawa T, Islam MT, Krug SM, Fromm M, Karaki S, Suzuki Y, Kuwahara A, Yoshiki H, Sada K, Muramatsu I, Anisuzzaman AS and Taniguchi T.
- Journal Title
  
  FEBS Letter
  
  Volume: 589 Pages: 3640-3547
- DOI
  10.1016/j.febslet.2015.10.029
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182, KAKENHI-PROJECT-15K08250, KAKENHI-PROJECT-15K10654, KAKENHI-PROJECT-26860170
[Journal Article] Involvement of the gut chemosensory system to the regulation of colonic anion secretion2015
- Author(s)
  Kuwahara A.
- Journal Title
  
  BioMed. Res. Int.
  
  Volume: 2015 Pages: 403919-403919
- DOI
  10.1155/2015/403919
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Chemical sensing and its contribution to ion transport in the colon2015
- Author(s)
  Kuwahara Atsukazu
- Journal Title
  
  J. Kyoto Pref. Univ. Med.
  
  Volume: 124 Pages: 223-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08182
[Journal Article] Short-chain fatty acid sensing in rat duodenum.2015
- Author(s)
  Akiba Y, Inoue T, Kaji I, Higashiyama M, Iwamoto K, Watanabe M, Guth PH, Engel E, Kuwahara A, Kaunitz JD
- Journal Title
  
  J Physiol,
  
  Volume: 593 Pages: 585-599
- DOI
  10.1113/jphysiol.2014.280792
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-15K08182, KAKENHI-PROJECT-24220007
[Journal Article] Activation of TRPA1 by luminal stimuli induces EP4-mediated anion secretion in human and rat colon2012
- Author(s)
  Kaji I, Yasuoka Y, Karaki SI, Kuwahara A
- Journal Title
  
  Am.J.Physiol.
  
  Volume: 302(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Chemosense for luminal environment in the large intestine2011
- Author(s)
  Kaji I, Karaki SI and Kuwahara A
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131 Pages: 1691-1698
- NAID
  130001871765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] The G-protein on cholesterol-rich membrane microdomains mediates mucosal sensing of short-chain fatty acid and secretory response in rat colon2011
- Author(s)
  Yajima T, Inoue R, Yajima M, Tsuruta T, Karaki SI, Hiroa T and Kuwahara A
- Journal Title
  
  Acta Physiol.(Oxf.)
  
  Volume: 203 Pages: 381-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Chemosense for luminal environment in the large intestine2011
- Author(s)
  Kaji I, Karaki SI, Kuwahara A
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131(12) Pages: 1691-1698
- NAID
  130001871765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Propionate-induced epithelial K^+ and Cl^-/HCO_3^- secretion and free fatty acid receptor 2 (FFA2, GPR43)expression in the guinea pig distal colon2011
- Author(s)
  Karaki SI, Kuwahara A
- Journal Title
  
  Pflugers Arch (European J.Physiol.)
  
  Volume: 461 Pages: 142-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Effects of luminal thymol on epithelial transport in human and rat colon2011
- Author(s)
  Kaji I, Karaki SI and Kuwahara A
- Journal Title
  
  Am. J. Physiol
  
  Volume: 300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Effects of luminal thymol on epithelial transport in human and rat colon2011
- Author(s)
  Kaji I, Karaki SI, Kuwahara A
- Journal Title
  
  Am.J.Physiol.
  
  Volume: 300(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] The G-protein on cholesterol-rich membrane microdomains mediates mucosal sensing of short-chain fatty acid and secretory response in rat colon2011
- Author(s)
  Yajima T, Inoue R, Yajima M, Tsuruta T, Karaki, SI, Hira T, Kuwahara A
- Journal Title
  
  Acta Physiol.
  
  Volume: 203 Pages: 381-389
- DOI
  10.1111/j.1748-1716.2011.02331.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Propionate-induced epithelial K+and Cl-/HCO3-secretion and free fatty acid receptor 2(FFA2, GPR43) expression in the guinea pig distal colon2011
- Author(s)
  Karaki SI and Kuwahara A
- Journal Title
  
  Pflugers Arch
  
  Volume: 461 Pages: 461-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide2011
- Author(s)
  Kaji I, Karaki SI, Tanaka R, Kuwahara A.
- Journal Title
  
  J.Molecular Histology
  
  Volume: 42 Pages: 27-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Density distribution of free fatty acid receptors(FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide2011
- Author(s)
  Kaji I, Karaki SI, Tanaka R and Kuwahara A
- Journal Title
  
  J. Mol. Histol
  
  Volume: 42 Pages: 27-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Free fatty acid receptors and their physiological roles in the colon2010
- Author(s)
  Karaki SI, Kuwahara A.
- Journal Title
  
  Medycyna Wet 66
  
  Pages: 147-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Role of short-chain fatty acids and their receptors in colonic motility (Review)2010
- Author(s)
  Karaki SI, Kuwahara A
- Journal Title
  
  Bioscience Microflora
  
  Volume: 29 Pages: 31-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Role of short-chain fatty acids and their receptors in colonic motility2010
- Author(s)
  Karaki SI and Kuwahara A
- Journal Title
  
  Bioscience Microflora
  
  Volume: 29 Pages: 31-40
- NAID
  10026975176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Free fatty acid receptors and their physiological roles in the colon2010
- Author(s)
  Karaki SI and Kuwahara A
- Journal Title
  
  Medycyna Wet
  
  Volume: 66 Pages: 147-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] 大腸内の短鎖脂肪酸とその受容体による大腸運動の制御-腸内細菌と生体との橋渡しによる生体ホメオスタシスの制御2010
- Author(s)
  唐木晋一郎、桑原厚和
- Journal Title
  
  化学と生物
  
  Volume: 48 Pages: 230-232
- NAID
  10026438009
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Expression of short-chain fatty acid receptor GPR41 in the human colon2009
- Author(s)
  Tazoe H, Otomo Y, Karaki SI, Kato I, Fukami Y, Terasaki M and Kuwahara A
- Journal Title
  
  Biomedical Res
  
  Volume: 30 Pages: 149-156
- NAID
  130005449544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Secretory effects of a luminal bitter tastant and expressions of bitter taste receptors, T2Rs, in the human and rat large intestine2009
- Author(s)
  Kaji I, Karaki SI, Fukami Y, Terasaki M and Kuwahara A
- Journal Title
  
  Am. J. Physiol
  
  Volume: 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Expression of short-chain fatty acid receptor GPR41 in the human colon2009
- Author(s)
  Tazoe H, Otomo Y, Karaki SI, Kato I, Fukami Y, Terasaki M, Kuwahara A.
- Journal Title
  
  Biomed.Res. 30
  
  Pages: 149-156
- NAID
  130005449544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] Secretory effects of a luminal bitter tastant and expressions of bitter taste receptors, T2Rs, in the human and rat large intestine2009
- Author(s)
  Kaji I, Karaki S, Fukami Y, Terasaki M, Kuwahara A.
- Journal Title
  
  Am.J.Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Journal Article] 大腸の腸管神経系Entelic Nervous System-II.大腸運動調節、粘膜上皮における水・電解質輸送調節、および生体防御機構に対する関与-2008
- Author(s)
  唐木晋一郎・桑原厚和
- Journal Title
  
  FFI Journal 213
  
  Pages: 157-168
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Expression of the short-chain fatty acid receptor, GPR43, in human Colon2008
- Author(s)
  Karaki, S.-I., Tazoe, H., Hayashi, H., Kashiwabara, H., Tooyama, K., Suzuki, Y. and Kuwahara, A
- Journal Title
  
  Journal of Molecular Histology 38
  
  Pages: 135-142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] 大腸の腸管神経系Enteric Nervous System-II.大腸運動調節、粘膜上皮における水・電解質輸送調節、および生体防御機構に対する関与-2008
- Author(s)
  唐木晋一郎・桑原厚和
- Journal Title
  
  FFI Journal 213
  
  Pages: 157-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglaindins, sensory afferent neuropeptides and nitric oxides2008
- Author(s)
  Brzozowski, T., Konturek, P. C., Sliwowski, Z., Drozdowicz, D., Burnat, G., Pajdo, R., Pawlik, M., Bielanski, W., Kato, I., Kuwahara, A., Konturek, S. J. and Pawlik, W. W.
- Journal Title
  
  Regulatory peptides Available online 20, Feb,
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Expression of the short-chain fatty acid receptol,GPR43,in human colon2008
- Author(s)
  Karaki, S.-I., Tazoe, H., Hayashi, H.Kashiwabara, H., Tooyama, K., Suzuki, Y.and Kuwahara, A
- Journal Title
  
  Journal of Molecular Histology 38
  
  Pages: 135-142
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglaindins,sensory afferent neuropeptides and nitric oxides2008
- Author(s)
  Brzozowski, T., Konturek, P.C., Sliwowski, Z., Drozdowicz, D., Burnat, G, Pajdo, R., Pawlik, M., Bielanski, W., Kato, I., Kuwahara, A., Konturek, S.J.and Pawlik, W.W
- Journal Title
  
  Regulatory peptides Available online 20,Feb
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Expression of the short-chain fatty acid receptor, GPR43, in human colon2008
- Author(s)
  Karaki, S.-I., Tazoe, H., Hayashi, H. Kashiwabara, H., Tooyama, K., Suzuki, Y. and Kuwahara, A.
- Journal Title
  
  Journal of Molecular Histology 38
  
  Pages: 135-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] The tight junction component protein, claudin-4, is expressed by enteric neurons in the rat distal colon2007
- Author(s)
  Kairki, S. -I., Kaji, I., Otomo, Y., Tazoe, H. and Kuwahara, A.
- Journal Title
  
  Neuroscience Letters 428
  
  Pages: 88-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] 大腸の水・電解質輸送調節機構-腸管神経系-内分泌系-免疫系およびプロスタグランジンの関与-2007
- Author(s)
  唐木晋一郎・桑原厚和
- Journal Title
  
  G. I. Research 15
  
  Pages: 43-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] 大腸の水・電解質輸送調節機構-腸管神経系-内分泌系-免疫系およびプロスタグランジンの関与-2007
- Author(s)
  唐木晋一郎・桑原厚和
- Journal Title
  
  GI.Research 15
  
  Pages: 43-53
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] 大腸の腸管神経系Enteric Nervous System-I.腸管神経細胞の形態・機能的分類と神経回路-2007
- Author(s)
  唐木晋一郎・桑原厚和
- Journal Title
  
  FFI Journal 212
  
  Pages: 1044-1053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] 大腸の腸管神経系Entedc Nervous System-I.腸管神経細胞の形態・機能的分類と神経回路-2007
- Author(s)
  唐木晋一郎・桑原厚和
- Journal Title
  
  FFI Journal 212
  
  Pages: 1044-1053
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] The tight junction component protein,claudin-4,is expressed by enteric neurons in the rat distal colon2007
- Author(s)
  Kairki, S.-I., Kaji, I., Otomo, Y., Tazoe, H.and Kuwahara, A
- Journal Title
  
  Neuroscience Letters 428
  
  Pages: 88-92
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Cellular expression of monocarboxylate transporter(MCT) in the digestive tract of the mouse, rat, and human, with special reference to Slc5a8.2006
- Author(s)
  Iwanaga, T., Takebe, K., Kato, I., karaki, S.-I., Kuwahara, A.
- Journal Title
  
  Biomedical Research 27(5)
  
  Pages: 243-254
- NAID
  130004470668
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Fiber-free diet leads to impairment of neuronally mediated muscle contractile response in rat distal colon.2006
- Author(s)
  Mitsui, R., Karaki, S.-I., Kubo, Y., Sugiura, Y., Kuwahara, A.
- Journal Title
  
  Neurogastroenterology ＆ Motility 18
  
  Pages: 1093-1101
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a82006
- Author(s)
  Iwanaga, T., Takebe, K., Kato, I., Karaki, S., Kuwahara, A
- Journal Title
  
  Biomedical Research 27
  
  Pages: 243-254
- NAID
  130004470668
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] The short chain fatty acid receptor, GPR43, is expressed by enteroeodncrine cells and mucosal mast cells in the rat intestine.2006
- Author(s)
  Karaki, S., Mitsui, R., Hayashi, H., Kato, I., Sugiya, H., Iwanaga, T., Furuness, J.B., Kuwahara, A.
- Journal Title
  
  Cell ＆ Tissue Research 324(3)
  
  Pages: 353-360
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Fibre-free diet leads to impairment of neuronally mediated muscle Contractile response in rat distal colon2006
- Author(s)
  Mitsui, R., Karaki, S.-I., Kubo, Y., Sugiura, Y., Kuwahara, A
- Journal Title
  
  Neurogastroenterology & Motility 18
  
  Pages: 1093-1101
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] A.2008. The tight junction component protein, claudin-4, is expressed by Enteric neurons in the rat distal colon
- Author(s)
  Karaki, S.-I., Kaji, I., Otomo, Y., Tazoe, H., Kuwahara
- Journal Title
  
  Neuroscience Letters 428
  
  Pages: 88-92
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine Cells and mucosal mast cells in the rat intestine
- Author(s)
  karaki, S.-I., Mitsui, R., Hayashi, H., Kato, I., Sugiya, H., Iwanaga, T., Furness, J.B., Kuwahara, A
- Journal Title
  
  Cell & Tissue research 324
  
  Pages: 353-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Journal Article] Activation of TRPA1 by luminal stimuli induces EP4-mediated anion secretion in human and rat colon
- Author(s)
  Kaji I, Yasuoka Y, Karaki SI and Kuwahara A
- Journal Title
  
  Am. J. Physiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Xenin evokes anion secretion through non-cholinergic secretomotor neurons in rat ileum2018
- Author(s)
  Kuwahara Y, kuwahara A, Marunaka Y, Kato I
- Organizer
  The 95 th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-15K08182
[Presentation] Characterization of the biological activity of xenin fragments on spontaneous circular muscle contraction in rat distal colon2017
- Author(s)
  Kuwahara A et al.
- Organizer
  The Physiological Society of Japan
- Place of Presentation
  Hamamatsu
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K08182
[Presentation] Contribution of colonic short-chain fatty acid receptors in energy homeostasis2015
- Author(s)
  Kuwahara A
- Organizer
  Polish Academy of Science
- Place of Presentation
  Warsaw, Poland
- Year and Date
  2015-12-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K08182
[Presentation] Chemical sensing in the colon2015
- Author(s)
  Kuwahara A
- Organizer
  Probiotics 2015
- Place of Presentation
  San Francisco
- Year and Date
  2015-07-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Presentation] Effects of Xenin on spontaneous circular muscel contraction in rat distal colon2015
- Author(s)
  Kuwahara Y, Karaki S, Tomizawa Y, Kato I, Kuwahara A
- Organizer
  ８thFAOPS
- Place of Presentation
  Bankok
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08182
[Presentation] ヒト及びラット大腸粘膜の陰イオン分泌におけるTRPA1チャネルの関与2011
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  2011年度生理学研究所研究会『上皮細胞の恒常性維持機構におけるイオン・物質輸送の新しい分子生理』(自然科学研究機構自然科学研究機構基礎生物学研究所)
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Mode of action of PGE_2 on the motility of longitudinal muscle in rat colon2011
- Author(s)
  Iizuka Y, Karaki SI, Kaji I, Kuwahara A
- Organizer
  7th Congress of the Federations of Asian and Oceanian Physiological Societies(FAOPS)
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ラット結腸・縦走筋運動におけるEP受容体分布の詳細について2011
- Author(s)
  飯塚祐美子, 唐木晋一郎, 加治いずみ, 桑原厚和
- Organizer
  第17回Hindgut Club Japanシンポジウム
- Place of Presentation
  専修大学・神田キャンパス
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Secretory response to TRPA1 activation in rat and human colon2011
- Author(s)
  Kaji I, Karaki SI, Kuwahara A
- Organizer
  7th Congress of the Federations of Asian and Oceanian Physiological Societies(FAOPS)
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ラット中位結腸縦走筋におけるPGE2の運動促進作用に関与するプロスタグランジン受容体の同定2010
- Author(s)
  飯塚祐美子, 唐木晋一郎, 田中亮, 加治いずみ, 桑原厚和
- Organizer
  第16回Hindgut Club Japanシンポジウム
- Place of Presentation
  専修大学,東京都
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ヒト及びラット大腸における匂い物質の感受と分泌作用2010
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ヒト及びラット大腸のイオン輸送作用における匂い物質受容の役割2010
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  第16回Hindgut Club Japanシンポジウム
- Place of Presentation
  専修大学,東京都
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] 大腸機能に対する化学センサー受容体FFA2およびFFA3の役割2010
- Author(s)
  桑原厚和, 唐木晋一郎, 加治いずみ
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ヒト及びラット大腸における匂い物質の受容と分泌作用2010
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  生理研研究会『極性細胞の病態生理解明に向けた多角的アプローチ』
- Place of Presentation
  自然科学研究機構生理学研究所,岡崎市
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] 消化管でのカリウムイオン輸送について2010
- Author(s)
  桑原厚和, 加治いずみ, 唐木晋一郎
- Organizer
  第2回消化管セミナー
- Place of Presentation
  北海道大学,札幌市
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ラット結腸輪走筋の自発運動に対するプロスタグランジンE_2の作用2010
- Author(s)
  唐木晋一郎, 田中亮, 加治いずみ, 桑原厚和
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Fructo-origosaccharide(FOS) supplementation increases enteroendocrine L cells containing GLP-1 and SCFA receptor GPR43(FFA2) in the large intestine2010
- Author(s)
  Kaji I, Karaki SI, Kuwahara A
- Organizer
  2010 Digestive Disease Week
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] プロスタグランジンE2受容体と大腸の自発運動との関係について2009
- Author(s)
  田中亮, 加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  第15回Hindgut Club Japanシンポジウム
- Place of Presentation
  専修大学
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ヒト及びラット下部消化管における苦味物質の受容と分泌作用2009
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  生理研研究会「上皮組織における細胞外環境感受機構」
- Place of Presentation
  自然科学研究機構生理学研究所
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Distributions of short-chain fatty acid receptors GPR41 and GPR43 in the human colon2009
- Author(s)
  Tazoe H, Otomo Y, Kaji I, Tanaka R, Karaki SI, Kuwahara A
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] tastant, 6-n-propyl-2-thiouracil(6-PTU) evokes anion secretion through bitter taste receptors in the human and rat large intestine2009
- Author(s)
  Kaji I, Karaki SI, Kuwahara A
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ヒト及びラット下部消化管における苦味物質の受容と分泌作用2009
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  第15回Hindgut Club Japanシンポジウム
- Place of Presentation
  専修大学
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Bitter taste receptor(T2R) ligand, 6-n-propyl-2-thiouracil(6-PTU)-evoked anion secretion in human and rat colon : interaction with COX-2 activity2009
- Author(s)
  Kaji I, Karaki SI, Kuwahara A
- Organizer
  Neurogastroenterology and Motility 2009 Joint International Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] 大腸運動と短鎖脂肪酸2009
- Author(s)
  田副秀章, 唐木晋一郎, 桑原厚和
- Organizer
  第1回消化管セミナー「栄養素の認識と消化管機能:受容体とトランスポーターの役割」
- Place of Presentation
  北海道大学創成科学共同研究棟
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] 消化管短鎖脂肪酸受容体の発現様式とその生理作用2009
- Author(s)
  桑原厚和
- Organizer
  第13回腸内細菌学会
- Place of Presentation
  北里大学薬学部
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Mode of effects of propionate on the motility of circular smooth muscle in the terminal ileum2009
- Author(s)
  Tazoe H, Karaki SI, Kuwahara A
- Organizer
  Neurogastroenterology and Motility 2009 Joint International Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] ヒトおよびラット下部消化管における苦味受容体の生理機能に関する研究2009
- Author(s)
  加治いずみ, 唐木晋一郎, 桑原厚和
- Organizer
  第1回消化管セミナー「栄養素の認識と消化管機能:受容体とトランスポーターの役割」
- Place of Presentation
  北海道大学創成科学共同研究棟
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-21590235
[Presentation] Neural reflex pathways in the contractile and secretory actions of short-chain fatty acids in the rat intestine2007
- Author(s)
  Karaki, S. -I., Tazoe, H., Ono, S. and Kuwahara, A.
- Organizer
  5th Congress of the International Society for Autonomic Neuroscience
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-18590207
[Presentation] Neural reflex pathways in the contractile and secretory actions of short Chain fatty acids in the rat intestine.2007
- Author(s)
  karaki, S.-I., Tazoe, H., Ono, S. and Kuwahara, A
- Organizer
  5th Congress of the International Society for Autonomic Nuroscience (ISAN2007)
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Presentation] Neural reflex pathways in the contractile and secretory actions of short-chain fatty acids in the rat intestine2007
- Author(s)
  Karaki, S.-I, Tazoe, H., Ono, S.and Kuwahara, A
- Organizer
  5th Congress of the International Society for Autouomic Neuroscience
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Presentation] Effects of short-chain fatty acids on large intestinal motility and their mode of detection2006
- Author(s)
  Karaki, S.-I., Mitsui, R., Ono, S., Tazoe, H., Yajima, T., Furness, J.B., Kuwahara, A
- Organizer
  2006 Joint International Society Meeting in Neurogastroenterology and GI Motility
- Place of Presentation
  Seaport Hotel and World Trade Center Boston, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207
[Presentation] Role of prostaglandins for transepithelial ion transport in the guinea-pig distal colon.2006
- Author(s)
  karaki, S.-I., Tazoe, H., Kuwahara, A
- Organizer
  The 6th Congress of the Federation of Asian and Oceanian Physiological Societies
- Place of Presentation
  Central City/JM Marriott Hotel, Seoul Korea
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590207

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KUWAHARA ATSUKAZU 桑原 厚和

桑原 厚和 クワハラ アツカズ

Kuwahara Atsukazu 桑原 厚和

KUWAHARA Atsukazu 桑原 厚和

KUWAHARA Atukazu 桑原 厚和

Research Projects

Research Products

Co-Researchers

消化管粘膜上皮化学物質受容機構を介した肥満等代謝性疾患予防に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of Chemosensory System on Intestinal Epithelial FunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the mechanism of epithelial ion transport mediated by Chemical receptors expressed in the colonic mucosaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of ion transpot by short chain fatty acids receptor, GPR43 in colonic epitheliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Physiology of neurotransmitters, VIP and 5-HT in the Gastrointestinal TractPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

食道横紋筋を支配するガラニン含有神経の機能的役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the intracellular second messenger pathway in the intestinal epithelial cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

消化管粘膜イオン輸送制御機構における伝達物質の放出動態に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of neuropeptide reseptor and its antagonists

Principal Investigator

Project Period (FY)

Research Category

Research Institution

新規生理活性物質、PACAPによる消化管粘膜イオン輸送調節機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of water and electrolyte transport in the gutPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Involvement of enterochromaffin (EC) cells in diarrhea

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Joint study on design, synthesis and analysis of agonists and antagonists of galanin

Principal Investigator

KUWAHARA ATSUKAZU 桑原厚和

桑原厚和クワハラアツカズ

Kuwahara Atsukazu 桑原厚和

KUWAHARA Atsukazu 桑原厚和

KUWAHARA Atukazu 桑原厚和