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Furuya Sonoko  古家 園子

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… Alternative Names

FURUYA Sonoko  古家 園子

古屋 園子  フルヤ ソノコ

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Researcher Number 20096952
Other IDs
Affiliation (Current) 2022: 生理学研究所, 脳機能計測・支援センター, 特別協力研究員
Affiliation (based on the past Project Information) *help 2014: 生理学研究所・個別研究, 村上正隆, 特別協力研究員
2012 – 2014: 生理学研究所, 個別研究 村上正隆, 特別協力研究員
2004 – 2006: 自然科学研究機構, 生理学研究所, 助手
2004: 名古屋大学, 自然科学研究機構・生理学研究所, 助手
2004: National Institute for Physiological Sciences, Center for Brain Experiment, Research Associate, 脳機能計測センター, 助手 … More
1999 – 2003: National Institute for Physiologocal Sciences, research associate, 生理学研究所, 助手
1996: National Institute for Physiological Sciences, 生理学研究所, 助手
1990 – 1996: 岡崎国立共同研究機構, 生理学研究所, 助手
1994: 岡崎国立共同研究機構, 整理学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
General anatomy (including Histology/Embryology) / Nerve anatomy/Neuropathology / General anatomy (including Histology/Embryology)
Except Principal Investigator
Gastroenterology / Gastroenterology / Biological Sciences / General physiology
Keywords
Principal Investigator
小腸 / アストロサイト / ギャップ結合 / エンドセリン / Furaー2 / ビメンチン / Fura-2 / 筋繊維芽細胞 / small intestine / 筋線維芽細胞 … More / 免疫組織化学 / IP3 / ATP / 毛細血管内皮細胞 / 腎糸球体 / 肺胞 / 電顕オ-トラジオグラフィ- / エンドセリンB受容体 / ヒルシュスプラング病 / ICs細胞 / 大腸 / Myenteric Plexus / 線維芽細胞 / アクチン / サイクリックAMP / カルシウムイオン / ジブチリルサイクリックAMP / セロトニン / fibroblasts / astrocytes / endothelin / actin / cyclic-AMP / Ca / interstitial cell / モノクローナル抗体 / GFAP / 脳 / 小腸絨毛下線維芽細胞 / Ca^<2+>波の伝播 / ATP受容体 / フリーズフラクチャー / 小腸繊毛下線維芽細胞 / cAMP / 蛍光免疫組織化学 / IP3受容体 / Gap junction / subepithelial fibroblast / Ca^<2+> wave / ATP receptor / immunohistochemistry / Freeze fracture / 絨毛上皮下線維芽細胞 / T84細胞 / 上皮細胞 / 細胞間Ca^<2+>シグナリング / メカノセンサー / 機械的刺激 / 水チャネル / RT-PCR / 神経 / subepithelial fibroblasts / T84 cells / epithelial cells / Ca2+ signaling / mechano-sensor / mechanical stimulation … More
Except Principal Investigator
CFTR / 膵導管細胞 / 単離小葉間膵管 / PACAP / グアニリン / 免疫組織化学 / 水チャネル / 慢性膵炎 / aquaporin / HCO_3^-分泌 / 5-hydroxytriptamine / VIP / pancreatic duct cell / プログアニリン / 受容体 / オートラジオグラフィー / 消化管 / 腎臓 / 水輸送 / HCO_3^-輸送 / SLC26 / 嚢胞線維症 / Na^+-HCO_3^-共輸送体 / 細胞内Cl^-濃度 / 構造活性相関 / エンドセリン / NMR spectroscopy / PRP / NMRスペクトル / guanylin / マイクロパーフュージョン / プリン受容体 / バゾプレッシン / TG repeat / chronic pancreatitis / fibrocystin / 内分泌 / 介在部導管 / 小葉内膵管 / 水透過性 / AQP1 / 細胞内小胞 / Na^+HCO_3^-cotransport / 膵管 / primary cilia / 多発性嚢胞腎症 / Primary cilia / ペプチドの構造 / ペプチドの化学合成 / NMRスペクトルスコピー / 脈管拡張物質 / 生理作用 / ペプチドの構造決定 / 二次元NMR / オ-トラジオグラフィ- / イオン交換HPLCカラム / 心房ペプチド / peptide structure / peptide synthesis / vasodilator / structure-activity relationship / physiological function / NMRスペクトル分析 / ラジオイムノアッセイ / セクレチン / endothelin / secretin / receptor / radioimmunoassay / ラジオレセプターアッセイ / 分子構造 / (1)グアニリン / (2)プログアニリン / (3)免疫組織化学 / (4)消化管 / (5)腎臓 / (6)ラジオレセプターアッセイ / (7)分子構造 / (8)オートラジオグラフィー / エンテロトキシン / 異性体 / 特異抗体 / 消化管粘膜 / エンテロクロマフィン細胞 / proguanylin / immunohistochemistry / gastrointestinal tract / kidney / radioreceptor assay / molecular structure / autoradiography / HCO^-_3分泌 / 管腔内微量灌流法 / アクアポリン / phospholipaseA2 / 膵腺房細胞 / 単離水腺房細胞 / PLA2 / Ca^<++>オシレーション / 重炭酸イオン / イオン輸送 / 膵血流 / HCOィイD23ィエD2ィイD1-ィエD1 secretion / purinoceptors / arginine vasopressin / pancreatic blood flow / phospholipase AィイD22ィエD2 / 重炭酸イオン輸送 / EC細胞 / エタノール / 過分泌 / アルコール性慢性膵炎 / 細胞内C1^-濃度 / Na^+-HCO_3^- cotransport / マイクロパーフュジョン / 細胞内pH測定 / HCO_3^-透過性 / Cl^- / HCO_3^-交換輸送体 / 単離膵導管細胞 / PLA_2 / Ca^<2+>オシレーション / bicarbonate transport / enterochromaffm cell / ethanol / fluid hypersecretion / alcoholic chronic pancreatitis / 汗中Cl^-濃度 / ポリT配列 / SLC26蛋白 / 膵HCO_3^-輸送 / 細胞内電位 / Cl^--HCO_3^-交換 / Na^+-HCO_3^-cotransport / CFTRクロライドチャンネル / CFTR遺伝子異常 / ポリT多型 / トランスジュニックマウス / 単離導管細胞 / 水分泌測定 / sweat chloride concentration / poly T / HCO_3^- secretion / SLC26 transporter / Na^+-H^+交換(NHE) / SLC26輸送担体 / 嚢胞性線維症 / 遺伝子変異 / RNAi / 遺伝子多型 / センサー分子 / water tranport / HCO_3- transport / Na^+-H^+ exchange (NHE) / SLC26 transporters / cystic fibrosis Less
  • Research Projects

    (16 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (33 People)
  •  A study of molecular pathogenesis of chronic pancreatitis by using polycystic kidney rat

    • Principal Investigator
      ISHIGURO Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Molecular pathogenesis of chronic pancreatitis: CFTR and intraductal sensor molecules

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Signal transduction from subepithelial fibroblasts to absorptive epithelial cells in the rat small intestine.Principal Investigator

    • Principal Investigator
      FURUYA Sonoko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      National Institute for Physiological Science
      Okazaki National Research Institutes
  •  消化管における水チャネル機能と水輸送のダイナミックス

    • Principal Investigator
      成瀬 達
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  Roles of CFTR chloride channel in the pathogenesis of chronic pancreatitis

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Molecular mechanisms of chronic pancreatitis : Ethanol-induced dysfunction of ion channels

    • Principal Investigator
      HAYAKAWA Tetsuo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  Ca^<2+> signaling in the subepithelial fibroblasts of small intestinePrincipal Investigator

    • Principal Investigator
      FURUYA Sonoko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      National Institute for Phy siological Sciences
  •  Molecular mechanisms of ion transport and clinical application

    • Principal Investigator
      HAYAKAWA Tetsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General physiology
    • Research Institution
      Nagoya University
  •  エンドセリンB受容体を持つ腸管筋層間線維芽細胞様介在細胞の機能とネットワーク構築Principal Investigator

    • Principal Investigator
      古家 園子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Okazaki National Research Institutes
  •  グアニリン産生細胞の免疫学的、分子生物学的同定とその生理作用の研究

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Nagoya University
  •  グアニリンの分子構造、細胞学、生理学とその臨床応用

    • Principal Investigator
      HAYAKAWA Tetsuo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  Molecular recognition of vasoactive peptides : basis for Physiological action

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  脳アストロサイトと腸管筋線維芽細胞の免疫学的類似性-Principal Investigator

    • Principal Investigator
      古家 園子
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Okazaki National Research Institutes
  •  エンドセリン受容体を持つ毛細血管内皮細胞の構造と機能Principal Investigator

    • Principal Investigator
      古家 園子
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Structure and function of fibroblasts which have endothelin receptorsPrincipal Investigator

    • Principal Investigator
      FURUYA Sonoko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Okazaki National Research Institute
  •  Biosyntesis and Physiological action of vasoactive peptides

    • Principal Investigator
      NARUSE Satoru
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okazaki National Research Institutes

All 2012 2005 2004 Other

All Journal Article

  • [Journal Article] Structure and Function of the Pancreas in the Polycystic Kidney Rat.2012

    • Author(s)
      Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H
    • Journal Title

      Pancreas.

      Volume: (in press) Pages: 1292-1298

    • DOI

      10.1097/mpa.0b013e31824c12f9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-24591010
  • [Journal Article] Characteristics of cultured subepithelial fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005

    • Author(s)
      Furuya S, Furuya K, T, Sokabe, Hirose T, Ozaki T
    • Journal Title

      Cell and Tissue Research 319

      Pages: 113-119

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Characteristics of subepithelial fibroblasts as a mechano-sensor in the intestine : Cell-shape dependent ATP release and P2Y1 signaling.2005

    • Author(s)
      Furuya K, Sokabe M, Furuya S
    • Journal Title

      J Cell Science (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Characteristics of cultured subepithelia fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005

    • Author(s)
      Furuya S, Furuya K, T, Sokabe, Hiroe T, Ozaki T
    • Journal Title

      Cell and Tissue Researc 319

      Pages: 113-119

    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Characteristics of cultured subepithelial fibroblasts in the rat small Intestine. II Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005

    • Author(s)
      Furuya S, Furuya K, Sokabe M, Hiroe T, Ozaki T
    • Journal Title

      Cell Tissue Research 319

      Pages: 113-119

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts as a mechanosensor in rat intestinal villi.2004

    • Author(s)
      Furuya S, Furuya K, Sokabe M.
    • Journal Title

      Anatomical Science International 79 Suppl 413

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts as a mechanosensor in rat intestinal villi.2004

    • Author(s)
      Furuya S, Furuya K, Sokabe M
    • Journal Title

      Anatomical Science International 79 Suppl

      Pages: 413-413

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts work as a mechano-sensor in the intestine.2004

    • Author(s)
      Furuya K, Furuya S, Sokabe M.
    • Journal Title

      Japanese Jornal of Physiology 34

    • NAID

      130005447436

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Subepithelial fibroblasts work as a mechano-sensor in the intestine.2004

    • Author(s)
      Furuya S, Furuya K, Sokabe M
    • Journal Title

      Japanese Journal of Physiology 34

    • NAID

      130005447436

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • [Journal Article] Charactaristics of subepithelial fibroblasts as a mechano-sensor in the intestine: Cell-shape dependent ATP release and P2Y1 signaling.

    • Author(s)
      Furuya K, Sokabe M, Furuya S
    • Journal Title

      J Cell Science (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590180
  • 1.  NARUSE Satoru (50180550)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  ISHIGURO Hiroshi (90303651)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  KITAGAWA Motoji (80262898)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  WARY Victor
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  FURUYA Kishio (40132740)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  OZAKI Tsutosi (20045694)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  NOKIHARA Kiyoshi (60137073)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  HAYAKAWA Tetsuo (80022838)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  NAGAHAMA Masato (50198355)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  NAGAO Shizuko (20183527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  FORSSMANN W.g.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  VICTOR WRAY
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  HERBST F.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  FORSSMANN W.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  NAKAKUKI MIyuki (30578729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  YAMAMOTO Akiko (60402385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  KUWAHARA Atsukazu (60142890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SEO Yositeru (90179317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KOBAYASHI Shigeru (00018342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KONDO Takaharu (20135388)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  中山 孝 (90150060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  CETIN Yalcin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TSUJI Shigeru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  F. HERBST
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  W.G. FORSSMA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  HERBST Franz
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  FORSSMNN W.G
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KLAUS Werner
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  TSUJI Shige
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  KIFFE michae
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  丸中 良典
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  CASE R.M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  YOSHIHARA Daisuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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