Furuya Sonoko 古家園子

… Alternative Names

FURUYA Sonoko 古家園子

古屋園子フルヤソノコ

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Researcher Number	20096952
Other IDs
Affiliation (Current)	2022: 生理学研究所, 脳機能計測・支援センター, 特別協力研究員
Affiliation (based on the past Project Information) *help	2014: 生理学研究所・個別研究, 村上正隆, 特別協力研究員 2012 – 2014: 生理学研究所, 個別研究村上正隆, 特別協力研究員 2004 – 2006: 自然科学研究機構, 生理学研究所, 助手 2004: 名古屋大学, 自然科学研究機構・生理学研究所, 助手 2004: National Institute for Physiological Sciences, Center for Brain Experiment, Research Associate, 脳機能計測センター, 助手 … More 1999 – 2003: National Institute for Physiologocal Sciences, research associate, 生理学研究所, 助手 1996: National Institute for Physiological Sciences, 生理学研究所, 助手 1990 – 1996: 岡崎国立共同研究機構, 生理学研究所, 助手 1994: 岡崎国立共同研究機構, 整理学研究所, 助手 Less
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / Nerve anatomy/Neuropathology / General anatomy (including Histology/Embryology) Except Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences / General physiology
Keywords	Principal Investigator 小腸 / アストロサイト / ギャップ結合 / エンドセリン / Furaー2 / ビメンチン / Fura-2 / 筋繊維芽細胞 / small intestine / 筋線維芽細胞 … More / 免疫組織化学 / IP3 / ATP / 毛細血管内皮細胞 / 腎糸球体 / 肺胞 / 電顕オ-トラジオグラフィ- / エンドセリンB受容体 / ヒルシュスプラング病 / ICs細胞 / 大腸 / Myenteric Plexus / 線維芽細胞 / アクチン / サイクリックAMP / カルシウムイオン / ジブチリルサイクリックAMP / セロトニン / fibroblasts / astrocytes / endothelin / actin / cyclic-AMP / Ca / interstitial cell / モノクローナル抗体 / GFAP / 脳 / 小腸絨毛下線維芽細胞 / Ca^<2+>波の伝播 / ATP受容体 / フリーズフラクチャー / 小腸繊毛下線維芽細胞 / cAMP / 蛍光免疫組織化学 / IP3受容体 / Gap junction / subepithelial fibroblast / Ca^<2+> wave / ATP receptor / immunohistochemistry / Freeze fracture / 絨毛上皮下線維芽細胞 / T84細胞 / 上皮細胞 / 細胞間Ca^<2+>シグナリング / メカノセンサー / 機械的刺激 / 水チャネル / RT-PCR / 神経 / subepithelial fibroblasts / T84 cells / epithelial cells / Ca2+ signaling / mechano-sensor / mechanical stimulation … More Except Principal Investigator CFTR / 膵導管細胞 / 単離小葉間膵管 / PACAP / グアニリン / 免疫組織化学 / 水チャネル / 慢性膵炎 / aquaporin / HCO_3^-分泌 / 5-hydroxytriptamine / VIP / pancreatic duct cell / プログアニリン / 受容体 / オートラジオグラフィー / 消化管 / 腎臓 / 水輸送 / HCO_3^-輸送 / SLC26 / 嚢胞線維症 / Na^+-HCO_3^-共輸送体 / 細胞内Cl^-濃度 / 構造活性相関 / エンドセリン / NMR spectroscopy / PRP / NMRスペクトル / guanylin / マイクロパーフュージョン / プリン受容体 / バゾプレッシン / TG repeat / chronic pancreatitis / fibrocystin / 内分泌 / 介在部導管 / 小葉内膵管 / 水透過性 / AQP1 / 細胞内小胞 / Na^+HCO_3^-cotransport / 膵管 / primary cilia / 多発性嚢胞腎症 / Primary cilia / ペプチドの構造 / ペプチドの化学合成 / NMRスペクトルスコピー / 脈管拡張物質 / 生理作用 / ペプチドの構造決定 / 二次元NMR / オ-トラジオグラフィ- / イオン交換HPLCカラム / 心房ペプチド / peptide structure / peptide synthesis / vasodilator / structure-activity relationship / physiological function / NMRスペクトル分析 / ラジオイムノアッセイ / セクレチン / endothelin / secretin / receptor / radioimmunoassay / ラジオレセプターアッセイ / 分子構造 / (1)グアニリン / (2)プログアニリン / (3)免疫組織化学 / (4)消化管 / (5)腎臓 / (6)ラジオレセプターアッセイ / (7)分子構造 / (8)オートラジオグラフィー / エンテロトキシン / 異性体 / 特異抗体 / 消化管粘膜 / エンテロクロマフィン細胞 / proguanylin / immunohistochemistry / gastrointestinal tract / kidney / radioreceptor assay / molecular structure / autoradiography / HCO^-_3分泌 / 管腔内微量灌流法 / アクアポリン / phospholipaseA2 / 膵腺房細胞 / 単離水腺房細胞 / PLA2 / Ca^<++>オシレーション / 重炭酸イオン / イオン輸送 / 膵血流 / HCOィイD23ィエD2ィイD1-ィエD1 secretion / purinoceptors / arginine vasopressin / pancreatic blood flow / phospholipase AィイD22ィエD2 / 重炭酸イオン輸送 / EC細胞 / エタノール / 過分泌 / アルコール性慢性膵炎 / 細胞内C1^-濃度 / Na^+-HCO_3^- cotransport / マイクロパーフュジョン / 細胞内pH測定 / HCO_3^-透過性 / Cl^- / HCO_3^-交換輸送体 / 単離膵導管細胞 / PLA_2 / Ca^<2+>オシレーション / bicarbonate transport / enterochromaffm cell / ethanol / fluid hypersecretion / alcoholic chronic pancreatitis / 汗中Cl^-濃度 / ポリT配列 / SLC26蛋白 / 膵HCO_3^-輸送 / 細胞内電位 / Cl^--HCO_3^-交換 / Na^+-HCO_3^-cotransport / CFTRクロライドチャンネル / CFTR遺伝子異常 / ポリT多型 / トランスジュニックマウス / 単離導管細胞 / 水分泌測定 / sweat chloride concentration / poly T / HCO_3^- secretion / SLC26 transporter / Na^+-H^+交換(NHE) / SLC26輸送担体 / 嚢胞性線維症 / 遺伝子変異 / RNAi / 遺伝子多型 / センサー分子 / water tranport / HCO_3- transport / Na^+-H^+ exchange (NHE) / SLC26 transporters / cystic fibrosis Less

A study of molecular pathogenesis of chronic pancreatitis by using polycystic kidney rat
- Principal Investigator
  
  ISHIGURO Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Molecular pathogenesis of chronic pancreatitis: CFTR and intraductal sensor molecules
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Signal transduction from subepithelial fibroblasts to absorptive epithelial cells in the rat small intestine.Principal Investigator
- Principal Investigator
  
  FURUYA Sonoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  National Institute for Physiological Science
  Okazaki National Research Institutes
消化管における水チャネル機能と水輸送のダイナミックス
- Principal Investigator
  
  成瀬達
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Roles of CFTR chloride channel in the pathogenesis of chronic pancreatitis
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Molecular mechanisms of chronic pancreatitis : Ethanol-induced dysfunction of ion channels
- Principal Investigator
  
  HAYAKAWA Tetsuo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Ca^<2+> signaling in the subepithelial fibroblasts of small intestinePrincipal Investigator
- Principal Investigator
  
  FURUYA Sonoko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  National Institute for Phy siological Sciences
Molecular mechanisms of ion transport and clinical application
- Principal Investigator
  
  HAYAKAWA Tetsuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General physiology
- Research Institution
  Nagoya University
エンドセリンB受容体を持つ腸管筋層間線維芽細胞様介在細胞の機能とネットワーク構築Principal Investigator
- Principal Investigator
  
  古家園子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Okazaki National Research Institutes
グアニリン産生細胞の免疫学的、分子生物学的同定とその生理作用の研究
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
グアニリンの分子構造、細胞学、生理学とその臨床応用
- Principal Investigator
  
  HAYAKAWA Tetsuo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
Molecular recognition of vasoactive peptides : basis for Physiological action
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
脳アストロサイトと腸管筋線維芽細胞の免疫学的類似性-Principal Investigator
- Principal Investigator
  
  古家園子
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Okazaki National Research Institutes
エンドセリン受容体を持つ毛細血管内皮細胞の構造と機能Principal Investigator
- Principal Investigator
  
  古家園子
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okazaki National Research Institutes
Structure and function of fibroblasts which have endothelin receptorsPrincipal Investigator
- Principal Investigator
  
  FURUYA Sonoko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Okazaki National Research Institute
Biosyntesis and Physiological action of vasoactive peptides
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Okazaki National Research Institutes

All 2012 2005 2004 Other

All Journal Article

[Journal Article] Structure and Function of the Pancreas in the Polycystic Kidney Rat.2012
- Author(s)
  Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H
- Journal Title
  
  Pancreas.
  
  Volume: (in press) Pages: 1292-1298
- DOI
  10.1097/mpa.0b013e31824c12f9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-24591010
[Journal Article] Characteristics of cultured subepithelial fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005
- Author(s)
  Furuya S, Furuya K, T, Sokabe, Hirose T, Ozaki T
- Journal Title
  
  Cell and Tissue Research 319
  
  Pages: 113-119
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Characteristics of subepithelial fibroblasts as a mechano-sensor in the intestine : Cell-shape dependent ATP release and P2Y1 signaling.2005
- Author(s)
  Furuya K, Sokabe M, Furuya S
- Journal Title
  
  J Cell Science (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Characteristics of cultured subepithelia fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005
- Author(s)
  Furuya S, Furuya K, T, Sokabe, Hiroe T, Ozaki T
- Journal Title
  
  Cell and Tissue Researc 319
  
  Pages: 113-119
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Characteristics of cultured subepithelial fibroblasts in the rat small Intestine. II Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.2005
- Author(s)
  Furuya S, Furuya K, Sokabe M, Hiroe T, Ozaki T
- Journal Title
  
  Cell Tissue Research 319
  
  Pages: 113-119
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Subepithelial fibroblasts as a mechanosensor in rat intestinal villi.2004
- Author(s)
  Furuya S, Furuya K, Sokabe M.
- Journal Title
  
  Anatomical Science International 79 Suppl 413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Subepithelial fibroblasts as a mechanosensor in rat intestinal villi.2004
- Author(s)
  Furuya S, Furuya K, Sokabe M
- Journal Title
  
  Anatomical Science International 79 Suppl
  
  Pages: 413-413
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Subepithelial fibroblasts work as a mechano-sensor in the intestine.2004
- Author(s)
  Furuya K, Furuya S, Sokabe M.
- Journal Title
  
  Japanese Jornal of Physiology 34
- NAID
  130005447436
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Subepithelial fibroblasts work as a mechano-sensor in the intestine.2004
- Author(s)
  Furuya S, Furuya K, Sokabe M
- Journal Title
  
  Japanese Journal of Physiology 34
- NAID
  130005447436
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590180
[Journal Article] Charactaristics of subepithelial fibroblasts as a mechano-sensor in the intestine: Cell-shape dependent ATP release and P2Y1 signaling.
- Author(s)
  Furuya K, Sokabe M, Furuya S
- Journal Title
  
  J Cell Science (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590180

1. NARUSE Satoru (50180550)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. ISHIGURO Hiroshi (90303651)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. KITAGAWA Motoji (80262898)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. WARY Victor

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. FURUYA Kishio (40132740)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. OZAKI Tsutosi (20045694)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. NOKIHARA Kiyoshi (60137073)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. HAYAKAWA Tetsuo (80022838)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. NAGAHAMA Masato (50198355)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. NAGAO Shizuko (20183527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. FORSSMANN W.g.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. VICTOR WRAY

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. HERBST F.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. FORSSMANN W.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. NAKAKUKI MIyuki (30578729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. YAMAMOTO Akiko (60402385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. KUWAHARA Atsukazu (60142890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SEO Yositeru (90179317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KOBAYASHI Shigeru (00018342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KONDO Takaharu (20135388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 中山孝 (90150060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. CETIN Yalcin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TSUJI Shigeru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. F. HERBST

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. W.G. FORSSMA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. HERBST Franz

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. FORSSMNN W.G

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KLAUS Werner

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TSUJI Shige

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KIFFE michae

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 丸中良典

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. CASE R.M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. YOSHIHARA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Furuya Sonoko 古家 園子

FURUYA Sonoko 古家 園子

古屋 園子 フルヤ ソノコ

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Signal transduction from subepithelial fibroblasts to absorptive epithelial cells in the rat small intestine.Principal Investigator

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エンドセリンB受容体を持つ腸管筋層間線維芽細胞様介在細胞の機能とネットワーク構築Principal Investigator

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脳アストロサイトと腸管筋線維芽細胞の免疫学的類似性-Principal Investigator

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エンドセリン受容体を持つ毛細血管内皮細胞の構造と機能Principal Investigator

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Structure and function of fibroblasts which have endothelin receptorsPrincipal Investigator

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Furuya Sonoko 古家園子

FURUYA Sonoko 古家園子

古屋園子フルヤソノコ