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SHINOZAKI Haruhiko  篠崎 温彦

ORCIDConnect your ORCID iD *help
Researcher Number 20109945
External Links
Affiliation (based on the past Project Information) *help 1999: 東京都医学研究機構, 研究員
1998: 財団法人 東京都臨床医学総合研究所, 薬理研究部門, 研究員
1996 – 1997: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Head., 薬理研究部門, 研究員
1996: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Head., 薬理研究部門, 研究員
1994 – 1996: 財団法人東京都臨床医学総合研究所, 薬理研究部門, 研究員 … More
1995: 東京都臨床医学総合研究所, 薬理, 部長
1994: The Tokyo Metropolitan Institute of Medical Science, Department of Pharmacology, Department Director, 薬理研究部門, 研究員
1994: 東京都臨床医学研究所, 薬理, 部長
1993 – 1994: 東京都臨床医学総合研究所, 部長
1993 – 1994: 財団法人 東京都臨床医学総合研究所, 薬理研究部門, 研究員
1993: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Department Di, 東京都臨床医学総合研究所・薬理研究部門, 研究員
1992 – 1993: (財)東京都臨床医学総合研究所, 薬理研究室長
1992: (財)東京都臨床医学総合研究所, 薬理研究部門, 研究員
1992: 東京都臨床医学総合研究所, 薬理研究室, 部長
1992: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Department Director, 薬理研究部門, 研究員
1991: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Head Research
1991: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Head Researcher, 薬理, 研究員
1990 – 1991: The Tokyo Metropolitan Institute of Medical Science, Pharmacology, Researcher, 薬理, 研究員
1990: 財, 東京都臨床医学総合研究所・薬理, 室長
1987 – 1989: (財)東京都臨床医学総合研究所, 薬理, 研究員
1987: 東京都臨床医学総合研究所, 薬理, 研究室長
1986: The Tokyo Metropolitan Institute of Medical Science, その他, 研究員 Less
Review Section/Research Field
Principal Investigator
医薬分子機能学 / 応用薬理学・医療系薬学 / Neurology / General pharmacology
Except Principal Investigator
Neurology / Biological pharmacy / Cerebral neurosurgery / 天然物有機化学 / 老化(加齢)
Keywords
Principal Investigator
代謝調節型グルタミン酸受容体 / グルタミン酸 / 神経細胞死 / 興奮性アミノ酸 / priming / 筋萎縮性側索硬化症 / 立体配座 / シナプス伝達 / グルタミン酸トランスポーター / 中枢抑制 … More / 辺縁系けいれん / カイニン酸誘発神経細胞死 / キスカル酸 / 脊髄運動神経細胞 / 2-(carboxycyclopropyl)glycine / NMDA型受容体 / フッ素置換体 / 神経可塑性 / アクロメリン酸 / Glutamate / Neuron damage / glutamate / グルタミン酸受容体アゴニスト / paraplegia / 神経細胞保護作用 / uptake阻害 / 長期抑制 / 脊髄 / 脊髄運動ニューロン / シナプス前抑制 / 単シナプス反射 / カイニン酸 / 海馬 / 長期抑圧 / Long term depression / synaptic transmission / neural plasticity / metabotropic glutamate receptor / glutamate transporter / グルタミン酸遮断薬 / 伝達物質放出 / 興奮性シナプス電位 / cyclicAMP / 長期増強 / quisqualate priming / グルホシネート / limbic motor seizures / L-AP4 / 受容体感受性 / 脊髄前角運動神経細胞 / クロマトライシス / 単シナプス脊髄反射 / α-アミノピメリン酸 / 出血 / BOAA / NOS inhibitor / MK-801 / グルタミン酸受容体 / L-NAME / 細胞内カルシウム / 立体異性 / Metabotropic receptors / Presynaptic inhibition / Monosynaptic reflex / Conformation / Stereochemistry / NMDAアンタゴニスト / cーfos / 片側半球壊死 / 脳虚血 / Metabotropic glutamate receptor / presynaptic inhibition / monosynaptic reflex / NMDA antagonist / 興奮性アシノ酸 / ラット脊髄 / 虚血性神経細胞死 / カイノイド / Amiotrophic lateral screrosis / Acromelic acid / Excitatory amino acid / Kainic acid / intrathecal injection / 辺緑系けいれん / Metabotropic glutamate receptors / Limbic motor seizures / Neuroprotective action / CNS depressant / piming / シナブス伝達 / 中枢抑制薬 / 除脳固縮 / 振戦 / オープンチャネルブロッカー / glutamate blocker / central nervous system depressant / decerebrate rigidity / tremor / 老人性痴呆 / スチゾロビン酸 / Glutamate blocker / Excitatory amino acids … More
Except Principal Investigator
神経細胞死 / アクロメリン酸 / カイニン酸 / 代謝調節型グルタミン酸受容体 / 興奮性アミノ酸 / グルタミン酸受容体 / DCG-IV / グルタミン酸 / 脳虚血 / priming / 受容体結合能 / AMPA / 脊髄 / ALS / 細胞死 / アポトーシス / ネクローシス / トキシコロジー / 重点領域研究 / カイノイド / 神経興奮作用 / アクロメリン酸誘導体 / 神経成長因子 / エンドセリン / 海馬 / Neuronal Death / Glutamate Receptor / Nerve Growth Factor / Endothelin / Hippocampus / グルタメート受容体 / カイノイドC_4側鎖の立体配座 / 4-フェニル-3-デヒドロプロリン / カルボキシシクロプロピルグリシン / カルボキシシクロペンチルグリシン / 立体配座解析 / アクロメリン酸B / 光照射下のジールズアルダー反応 / ピロリジン環の効率的形成 / Acromelic acid / Glutamate receptor / Configuration of C_4 side chain in kainoids / 4-phenyl-3-dehydroproline / Carboxycyclopropylglycine / Carboxycyclopentylglycine / Conformational analysis / 痙攀 / 痙攣 / 老人性痴呆 / 代謝調節型受容体 / metabotropic glutamate receptor / neuron damage / kainic acid / L-CCG-I / Excitatory amino acid / limbic motor seizures (8) / hippocampus CA3 / グルタミン / 神経可能性 / シナプス伝達 / グルタミン酸トランスポーター / 長期抑圧 / α-アミノピメリン酸 / 神経可塑性 / キスカル酸 / quisqualate priming / L-AP4 / カイニン酸様痙攣 / グルホシネート / glutamate / metabotropic glutamate receptors / neural plasticity / synaptic transmission / glutamate transporter / long term depression / DL-alpha-aminopimelic acid Less
  • Research Projects

    (28 results)
  • Co-Researchers

    (18 People)
  •  神経可塑性と代謝調節型グルタミン酸受容体の基礎的研究Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  新規代謝調節型グルタミン酸受容体アゴニストによる神経細胞保護作用の研究Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  グルタミン酸による選択的神経細胞死:筋萎縮性側索硬化症動物モデルへの応用Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  神経可塑性と代謝調節型グルタミン酸受容体の基礎的研究Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  グルタミン酸による神経細胞死:筋萎縮性側索硬化症モデル作成の試みPrincipal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  神経可塑性と代謝調節型グルタミン酸受容体の基礎的研究Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  新規代謝調節型グルタミン酸受容体アゴニストによるシナプス伝達の増強Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  化学物質による細胞障害の機構

    • Principal Investigator
      長尾 択
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Design and development of agonists for metabotropic glutamate receptors to protect against neuronal deathPrincipal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Basic research on metabotropic glutamate receptors and neural plasticity.

    • Principal Investigator
      ISHIDA Michiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Pharmacological probes for elucidating the physiological role of glutamate receptorsPrincipal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  代謝調節型グルタミン酸受容体の機能を解明するための薬理学的ツールの開発Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  選択的神経細胞死を誘発ないし防護する興奮性アミノ酸関連薬物の開発Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  代謝調節型グルタミン酸受容体の神経変性防護作用に関する研究

    • Principal Investigator
      郭 伸
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      The University of Tokyo
  •  グルタミン酸受容体の生理機能を解明するための薬理学的プローブの研究Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  グルタミン酸受容体の生理機能を解明するための薬理学的ツールの開発Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Design and development of excitatory amino acid related compounds for protection against senile neuronal deathPrincipal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  グルタミン酸受容体の生理機能を解明するための薬理学的ツールの開発Principal Investigator

    • Principal Investigator
      篠崎 温彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Roles of Excitatory Amino Acids, Endothelin and Nerve Growth Factor in Neuronal Death and Epilepsy.

    • Principal Investigator
      SHIGENO Taku
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Saitama Medical School
  •  DEVELOPMENT OF POTENT ACTIVE COMPOUNDS WORKING ON NEUROTRANSMIT ORGAN

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      天然物有機化学
    • Research Institution
      Hokkaido University
  •  Compounds for inhibiting kainate-induced neuron damage

    • Principal Investigator
      ISHIDA Michiko
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      老化(加齢)
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Animal models for amiotrophic lateral screrolis induced by an excitatory amino acid, acromelic acid.Principal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  アクロメリン酸の選択的神経細胞障害の発現機序:グルタミン酸受容体との関連

    • Principal Investigator
      KWAK Shin
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Drug Design and Development of Glutamate Blockers which protect against Neuronal Death.Principal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Molecular Mechanisms of Neuronal Death : Effects of Excitatory Amino AcidsPrincipal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  新カイノイドの化学合成による伝達物質と受容体との関係解明

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Hokkaido University
  •  Basic Research of the senile dementia: Cerebro-protective glutamate antagonists.Principal Investigator

    • Principal Investigator
      SHINOZAKI H.
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Pharmacological studies of the glutamate blocker and its application to central nervous system depressantPrincipal Investigator

    • Principal Investigator
      SHINOZAKI Haruhiko
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  • 1.  ISHIDA Michiko (90124437)
    # of Collaborated Projects: 22 results
    # of Collaborated Products: 0 results
  • 2.  UYAMA Yoshiaki (20281686)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  KWAK Shin (40160981)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  OHFUNE Yasufumi (20142078)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  SHIRAHAMA Haruhisa (00000802)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SHIGENO Taku (20170863)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  長尾 択 (30217971)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  高橋 道人 (30080005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  菅野 盛夫 (00109422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  井村 伸正 (70012606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  土井 邦雄 (70155612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  鈴木 英紀 (30158977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KONISHI Shiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MIYAMOTO Masashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IZAWA Toshio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  相澤 仁志
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小西 史朗
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  伊沢 敏雄
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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