KAWAHARA Koichi 河原剛一

Researcher Number	20125397
Other IDs
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Affiliation (based on the past Project Information) *help	2012: 北海道大学, -, 名誉教授 2012: 北海道大学, 名誉教授 2011: 北海道大学, 大学院・情報科学研究科, 特任教授 2011: 北海道大学, 情報科学研究科, 特任教授 2007 – 2010: Hokkaido University, 大学院・情報科学研究科, 教授 … More 2006: Hokkaido Univ., Grad. School of Info. Sci. and Tech., Prof., 大学院情報科学研究科, 教授 2006: Hokkaido Univ., Grad. School of Inf. Sci. & Tech., Prof., 情報科学研究科, 教授 2004 – 2005: 北海道大学, 大学院・情報科学研究科, 教授 1995 – 2003: 北海道大学, 電子科学研究所, 教授 1990 – 1992: Yamagata University, Faculty of Engineering. Professor, 工学部, 教授 1989: 山形大学, 工学部, 助教授 Less
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Embryonic/Neonatal medicine / 計測・制御工学 / Neurophysiology and muscle physiology Except Principal Investigator Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Nanomaterials/Nanobioscience / Medical systems
Keywords	Principal Investigator 心筋細胞 / 中脳歩行誘発野 / 歩行リズム / 呼吸リズム / 拍動リズム / 除脳ネコ / purinoceptor / ATP / ischemia / 細胞死 … More / 再灌流 / 虚血 / リズムゆらぎ / 神経振動子 / 睡眠時無呼吸 / 細胞内Ca^<2+>振動 / ミトコンドリア / 心室頻拍 / 心室細動 / 心拍リズム / 引き込み現象 / extracellular signaling / gap junction / contraction rhythm / cultured cardiac myocytes / Cx 43抗体 / 線維芽細胞 / 細胞外情報伝達系 / ギャップ結合 / 培養心筋細胞 / nitric oxide / mitochondria / ventricular tachycardia / ventricular fibrillation / remodeling / apoptosis / 一酸化窒素 / リモデリング / アポトーシス / myocyte death / beating rhythm / cardiac myocyte / reperfusion / brainstem-spinal cord preparation / CO2 sensitivity / newborn rat / sleep apnea / sudden infant death / 脳幹・脊髄標本 / 二酸化炭素感受性 / 新生ラット / 乳幼児突然死 / nonlinear interactions between oscillators / neural oscillators / ontogeny / fluctuation / heartbeat period / chick embyos / 振動子間相互作用 / 個体発生 / 心拍 / 鶏胚 / Fluctuation / Hierarchical Structures / Neural Oscillators / Stepping Rhythm / Respiratory Rhythm / Heart Beat / Mesencephalic Locomotor Region / Decerebrate Cats / 機能的階層構造 / リズム間相互結合 / ゆらぎ / 階層性 / Sleep Apnea / REM Sleep / Carbachol Injection / Apnea / Atonia / Dorsal Tegmental Field / 睡眠時無呼吸症候群 / 運動系の汎化抑制 / 脊髄投射 / 巨大細胞網様核 / カルバコル / 延髄巨大細胞性網様核 / レム睡眠 / apnea / atonia / カルバコ / 延髄巨大相胞性網様核 / 吻側橋網様核 / 橋中心被蓋野背側部 / 心筋細胞増殖能喪失 / 心筋損傷後再生 / 正帰還制御ループ / ラット心筋 / イモリ心筋 / 心筋細胞増殖 / 増殖能喪失 / 正帰還ループ / 酸化ストレス / 細胞周期 / 正帰還制御 / 活性酸素種 / 細胞分裂 / 核分裂 / Cx43 / p38 MAPK / ATP-purinocetor系 / 負帰還制御系 / 非線形振動子 / 細胞内Mg^<2+>振動 / 細胞外ATP振動 / ATP-purinoceptor系 / VF遷移 / VT / カルシウム / 状態依存性 / ゆうぎ / 振動子間結合 / 一方向性結合 / 位相反応曲面 / 位相反応曲線 / 可変結合 / 歩容 … More Except Principal Investigator SHR / skeletal muscle / near-infrared light / 組織酵素濃度 / 顕微分光 / 酸素消費量 / 組織酸素濃度 / 近赤外光 / muscle glucose uptake / feedforward control / 筋交感神経 / 筋糖代謝 / Microtubules / Cellular skeleton / Cardiomyocyte / Cardiac hypertrophy / energetics / Heart failure / Biomechanics / 発生応力 / 発生張力 / 細胞骨格 / エナジェティクス / 微小管 / 収縮張力 / 収縮性 / 心筋細胞 / 心肥大 / 心不全 / バイオメカニクス / microspectrophotometry / exercise tests / temporal and spatial analyses / oxygen consumption rate / muscle oxygenation / 運動負荷 / 時空間解析 / 筋 / microphotospectroscopy / myoglobin / hemoglobin / oxygen consumption / tissue oxygenation / ミオグロビン / ヘモグロビン / 骨格筋 / microneurogram / muscle sympathetic nerve / muscle contraction / the central nervous system / feedback control / 運動 / マイクロニューログラム / 筋収縮 / 中枢 / フィードフォワード制御 / フィードバック制御 / locomotion / muscle sympathetic nerve activity (MSNA) / ventromedial hypothalamus nuclei (VMH) / 筋血糖代謝 / 歩行運動 / 予測制御 / 視床下部腹内側核 / 細胞アレイ / レオロジー / 多変量解析 / 細胞力学 / 統計解析 / 細胞診断 / 細胞分化 / 細胞周期 / ナノ計測 / 細胞レオロジー / 多数細胞 / 原子間力顕微鏡 / パルス超音波 / 機械的作用 / 心室筋細胞 / 期外収縮 / 生体作用 / 微小気泡 / 超音波 Less

Ontogenetic and phylogenetic mechanisms involved in the loss of proliferation activity in mammalian cardiomyocytes after birth.Principal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Oxidative stress during fetal-neonatal transition and the formation of a positive-feedback loop for the terminal differentiation of mammalian cardiomyocytes.Principal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Statistical Analysis of Single Cell Mechanics by Atomic Force Microscopy
- Principal Investigator
  
  OKAJIMA Takaharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Hokkaido University
心筋細胞における核分裂と細胞分裂の解離:増殖と肥大のスイッチ機構Principal Investigator
- Principal Investigator
  
  河原剛一
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Coordination and dissociation of nonlinear oscillations in cardiomyocytes : dysfunction of holonic oscillators leading to arrhythmiasPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Discovering mechanisms to generate cardiac remodeling and decrease ischemic tolerance from mechanical inspection
- Principal Investigator
  
  NAIKI Takeru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
微小気泡存在下での超音波照射による期外収縮発生の機序:培養心室筋細胞を用いた検討
- Principal Investigator
  
  KUDO Nobuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical systems
- Research Institution
  Hokkaido University
Development of an instrument for temporal and spatial analyses of distribution of muscle oxygenation using near-infrared spectroscopy and its applications
- Principal Investigator
  
  YAMAMOTO Katsuyuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
Hierarchical Correlation Dynamics among Cellular Rhythms: Coordination and Dissociation of Non-linear Biological Oscillators.Principal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
ミトコンドリアによる心室頻拍-心室細動マクロダイナミクス遷移の制御Principal Investigator
- Principal Investigator
  
  河原剛一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Experimental verification of causal relationships between measurements of near-infrared spectroscopy and mechanisms of oxygen transport to skeletal muscles
- Principal Investigator
  
  YAMAMOTO Katsuyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
Ischemia-induced remodeling of the heart : macro- and micro-systems approach to heart functionPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
Nonlinear dynamics of heart beat rhythm during ischemia / reperfusion and death of cardiac myocytes.Principal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
Feedback and feedforward neural control of muscle glucose uptake during contraction
- Principal Investigator
  
  NAKAMURA Takao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
Development and assesment of the animal model for "sudden infant death syndrom".Principal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  HOKKAIDO UNIVERSITY
Ontogenetic changes in heartbeat fluctuation and nonlinear interactions between neural oscillatorsPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
Feedforward control of muscle glucose uptake during exercise by the nervous system
- Principal Investigator
  
  NAKAMURA Takao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  HOKKAIDO UNIVERSITY
内因性運動プログラム間結合の内部状態依存性Principal Investigator
- Principal Investigator
  
  河原剛一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
内因性運動プログラム間の結合・解離とその中枢制御Principal Investigator
- Principal Investigator
  
  河原剛一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
Interactions between Neural Oscillators and their Functional Hierarchical StructuresPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  計測・制御工学
- Research Institution
  YAMAGATA UNIVERSITY
中枢運動プログラム間の相互可変結合と並列制御Principal Investigator
- Principal Investigator
  
  河原剛一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
Neural Mechanisms of Sleep ApneaPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Koichi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yamagata Uneversity

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Negaitive-feedback regulation of ATP release during ischemia in cardiac myocytes. In: Proceedings of the IFMBE 39, Long2012
- Author(s)
  Kawahara, K. Kunugi, S, Matsuyama, D. and Iwabuchi, S.
- Publisher
  M. (Ed.), Springer-Verlag, Berlin
- Data Source
  KAKENHI-PROJECT-24650245
[Book] In: Proceedings ofthe IFMBE 37, Jobbagy, A. (Ed.), Springer-Verlag, Berlin2011
- Author(s)
  Kawahara, K. and Matsuyama, D.
- Publisher
  Positive-feedback regulation loop for the loss of cell division and binucleation shortly after birth in cardiomyocytes
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] Spatio-temporal spread of neuronal death after focal photolysis of caged glutamate in neuron/astrocyte co-cultures.2013
- Author(s)
  Sadahiro Iwabuchi
- Journal Title
  
  Neurochemistry International
  
  Volume: 62 Issue: 7 Pages: 1020-1027
- DOI
  10.1016/j.neuint.2013.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148, KAKENHI-PROJECT-24650245
[Journal Article] Negative-feedback regulation of ATP release during ischemia in cardiac myocytes.2012
- Author(s)
  Koichi Kawahara
- Journal Title
  
  IFMBE Proceedings
  
  Volume: 39 Pages: 2196-2199
- Data Source
  KAKENHI-PROJECT-24650245
[Journal Article] Effect of Isoproterenol on Local Contractile Behaviors of Rat Cardiomyocytes Measured by Atomic Force Microscopy2012
- Author(s)
  Y.Mizutani, K.Kawahara, T.Okajima
- Journal Title
  
  Current Pharmaceutical Biotechnology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] Direct observation of dynamic force propagation between focal adhesions of cells on microposts by atomic force microscopy2011
- Author(s)
  A.Okada, 他6名, T.Okajima
- Journal Title
  
  Appl.Phys.Lett.
  
  Volume: 99 Issue: 26 Pages: 263703-263703
- DOI
  10.1063/1.3672225
- NAID
  120003783352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079, KAKENHI-PUBLICLY-22018003, KAKENHI-PROJECT-22300148
[Journal Article] Gender differences in hand stability assessed in normal young people2011
- Author(s)
  Endo, H. and Kawahara, K.
- Journal Title
  
  Ergonomics
  
  Volume: 54(3) Pages: 273-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] Negative-feedback regulation of ATP release : ATP release from cardiomyocytes is strictly regulated during ischemia2011
- Author(s)
  Kunugi, 他2名, Okajima, T., Kawahara, K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 416 Issue: 3-4 Pages: 409-415
- DOI
  10.1016/j.bbrc.2011.11.068
- NAID
  120003762601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079, KAKENHI-PUBLICLY-22018003, KAKENHI-PROJECT-22300148
[Journal Article] Direct observation of dynamic force propagation between focal adhesions of cells on microposts by atomic force microscopy2011
- Author(s)
  A. Okada, Y. Mizutani, A. Subagyo, H. Hosoi, M. Nakamura, K. Sueoka, K. Kawahara, and T. Okajima
- Journal Title
  
  Appl. Phys. Lett
  
  Volume: 99
- NAID
  120003783352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] Functional significance of the negative-feedback regulation of ATP release via pannexin-1 hemichannels under ischemic stress in astrocytes2011
- Author(s)
  Iwabuchi, S. and Kawahara, K.
- Journal Title
  
  Neurochemistry International
  
  Volume: 58 Issue: 3 Pages: 376-384
- DOI
  10.1016/j.neuint.2010.12.013
- NAID
  120003464638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] Oxidativestress-induced formation of a positive-feedback loop for the sustained activation of p38 MAPK leading to the loss of cell division in cardiomyocytes soon after birth2011
- Author(s)
  Matsuyama, D. and Kawahara, K.
- Journal Title
  
  Basic Research in Cardiology
  
  Volume: 106 Issue: 5 Pages: 815-828
- DOI
  10.1007/s00395-011-0178-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] Rheological Properties of Growth-Arrested Fibroblast Cells under Serum Starvation Measured by Atomic Force Microscopy2011
- Author(s)
  A.Miyaoka, 他3名, T.Okajima
- Journal Title
  
  Jpn.J.Appl.Phys.
  
  Volume: 50 Issue: 8S3 Pages: 08LB16-08LB16
- DOI
  10.1143/jjap.50.08lb16
- NAID
  210000071145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079, KAKENHI-PUBLICLY-22018003, KAKENHI-PROJECT-22300148
[Journal Article] Rheological Properties of Growth-Arrested Fibroblast Cells under Serum Starvation Measured by Atomic Force Microscopy2011
- Author(s)
  A. Miyaoka, Y. Mizutani, M. Tsuchiya, K. Kawahara and T. Okajima
- Journal Title
  
  Jpn. J. Appl. Phys
  
  Volume: 50
- NAID
  210000071145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] 10 Hz periodic component influences lower frequency component of the physiological tremor at low force levels2011
- Author(s)
  Endo, H. and Kawahara, K.
- Journal Title
  
  European Journal of Applied Physiology
  
  Volume: 111 Issue: 11 Pages: 2695-2705
- DOI
  10.1007/s00421-011-1903-6
- NAID
  120004856988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] Inducible astrocytic glucose transporter-3 contributes to the enhanced storage of intracellular glycogen during reperfusion after ischemia2011
- Author(s)
  Iwabuchi, S. and Kawahara, K.
- Journal Title
  
  Neurochemistry International
  
  Volume: 59 Issue: 2 Pages: 319-325
- DOI
  10.1016/j.neuint.2011.06.006
- NAID
  120003340662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] Relationship between hand stability and the 10-Hz physiological tremor during various manual tasks2010
- Author(s)
  Endo, H. and Kawahara, K.
- Journal Title
  
  Ergonomics
  
  Volume: 53(4) Issue: 4 Pages: 491-501
- DOI
  10.1080/00140130903556336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300148
[Journal Article] The number distribution of complex shear modulus of single cells measured by atomic force microscopy2009
- Author(s)
  S. Hiratsuka, Y. Mizutani, M. Tsuchiya, K. Kawahara, H. Tokumoto, T. Okajima
- Journal Title
  
  Ultramicroscopy
  
  Volume: 109 Pages: 937-941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] Proliferation of neonatal cardiomyocytes by connexin43 knockdown via synergistic inactivation of p38 MAPK and increased expression of FGF12009
- Author(s)
  Matsuyama, D., Kawahara, K.
- Journal Title
  
  Basic Research in Cardiology 104(6)
  
  Pages: 631-642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] The number distribution of complex shear modulus of single cells measured by atomic force microscopy2009
- Author(s)
  Hiratsuka, S., Mizutani, Y., Tsuchiya, M., Kawahara, K., Tokumoto, H., Okajima, T.
- Journal Title
  
  Ultramicroscopy 109
  
  Pages: 937-941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] 互いに孤立した心筋細胞の同期現象 : 細胞間情報伝達の新しいメカニズム2009
- Author(s)
  河原剛一
- Journal Title
  
  心電図 29 Suppl. 5
- NAID
  10026293308
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Oxygen-glucose deprivation-induced enhancement of extracellular ATP-P2Y purinoceptors signaling for the propagation of astrocytic calcium waves2009
- Author(s)
  Iwabuchi, S., Kawahara, K.
- Journal Title
  
  BioSystems 96
  
  Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Power-Law stress and creep relaxations of single cells measured by colloidal probe atomic force microscopy2009
- Author(s)
  Hiratsuka, S., Mizutani, Y., Toda, A., Fukushima, N., Kawahara, K., Tokumoto, H., Okajima. T.
- Journal Title
  
  Japanese Journal of Applied Physics 48
- NAID
  210000067323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Possible involvement of extracellular ATP-P2Y purinoceptor signaling in ischemia-induced tolerance of astrocytes in culture2009
- Author(s)
  Iwabuchi, S., Kawahara, K.
- Journal Title
  
  Neurochemical Research 34(9)
  
  Pages: 1542-1554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Power-Law Stress and Creep Relaxations of Single Cells Measured by Colloidal ProbeAtomic Force Microscopy Jpn2009
- Author(s)
  S. Hiratsuka, Y. Mizutani, A. Toda, N. Fukushima, K. Kawahara, H. Tokumoto and T. Okajima
- Journal Title
  
  J. Appl. Phys
  
  Volume: 48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] Elasticity of living cells on a microarray during the early stages of adhesion measured by atomic force microscopy2008
- Author(s)
  Mizutani, Y., Tsuchia, M., Hiratsuka, S., Kawahara, K., Tokumoto, H., Okajima, T.
- Journal Title
  
  Japanese Journal of Applied Physics 47(7)
  
  Pages: 6177-6180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Rhythmic fluctuations in intracellular Mg2+ in spontaneously beating cultured cardiac myocytes2008
- Author(s)
  Kawahara, K., Sato, R., Matsuyama, D., Iwabuchi, S
- Journal Title
  
  Proceedings of the NBC 2008
  
  Pages: 264-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Rhythmic fluctuations in the concentration of intracellular Mg^<2+> in association with spontaneous, rhythmic contraction in cultured cardiac myocytes2008
- Author(s)
  Koichi Kawahara
- Journal Title
  
  Chronobiology International 25
  
  Pages: 868-881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Neuron is the primary target of Ca^<2+> paradox-type insult-induced cell injury in neuron/astrocyte co-cultures2008
- Author(s)
  Kosugi, T., Kawahara, K., Tanaka, M., Watanabe, Y., Inanami, O.
- Journal Title
  
  Neurochemistry International 52(4-5)
  
  Pages: 887-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Rhythmic fluctuations in the concentration of intracellular Mg^<2+> in association with spontaneous rhythmic contraction in cultured cardiac myocytes2008
- Author(s)
  Kawahara, K., Sato, R., Iwabuchi, S., Matsuyama, D.
- Journal Title
  
  Chronobiology International 25(6)
  
  Pages: 868-881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Changes in the Proliferation activity and spontaneous contraction rhythm of terminally differentiated cardiac myocytes by co-treatment with FGF1 and an inhibitor of p38 MAP Kinase2008
- Author(s)
  Matsuyama, D., Kawahara, K.
- Journal Title
  
  The 22nd SICE Symposium on Biological and Physiological Engineering, Harbin, China, January 13-14, 2008. (Proceedings of the International Symposium on Biological and Physiological Engineering)
  
  Pages: 337-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Maintenance and characterization of spontaneous contraction rhythm in cultured cardiac myocytes fused with cardiac fibroblasts2008
- Author(s)
  Matsuyama, D., Kawahara, K.
- Journal Title
  
  BioSystems 92
  
  Pages: 226-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Preconditioning-induced changes in the spontaneous calcium oscillations for the development of neuronal ischemic tolerance in neuron/astrocyte co-culture2007
- Author(s)
  Tanaka, M., Kawahara, K., Kosugi, T., Yamada, T., Mioka, T.
- Journal Title
  
  Neurochemical Research 32
  
  Pages: 988-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Changes in the fluctuation of the contraction rhythm of spontaneously beating cardiac myocytes in cultures with and without cardiac fibroblasts2007
- Author(s)
  Hachiro, T., Kawahara, K., Sato, R., Yamauchi, Y., Matsuyama, D.
- Journal Title
  
  BioSystems 90
  
  Pages: 707-715
- NAID
  120000951583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] 微小管量を変化させることによる肥大心筋細胞のエネルギ消費低減化の試み2007
- Author(s)
  水谷祐輔, 内貴猛, 河原剛一
- Journal Title
  
  生体医工学第45巻特別号(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Proceedings of the 19th Bioengineering Conference2007
- Author(s)
  T.Naiki, A.Hayashi, Y.Mizutani, K.Kawahara
- Journal Title
  
  06-65
  
  Pages: 262-263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Fluctuations in the concentration of extracellular ATP synchronized with intracellular Ca^<2+> oscillatory rhythm in cultured cardiac myocytes2007
- Author(s)
  Koichi Kawahara
- Journal Title
  
  Chronobiology International 24
  
  Pages: 1035-1048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] 心筋細胞内Ca2+振動の細胞間同期と自動能 : その新しいメカニズム2007
- Author(s)
  河原剛一
- Journal Title
  
  臨床と研究 84(3)
  
  Pages: 441-444
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Extracellular ATP-purinoceptor signaling for the intercellular synchronization of intracellular calcium oscillation in cultured cardiac myocytes2007
- Author(s)
  Kawahara, K., Nakayama, Y.
- Journal Title
  
  IFMBE Proceedings Volume 16
  
  Pages: 537-540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] 心筋肥大症におけるバイオメカニクス2007
- Author(s)
  内貴猛, 林あさこ, 水谷祐輔, 河原剛一
- Journal Title
  
  第19回バイオエンジニアリング講演会講演論文集 06-65
  
  Pages: 262-263
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Fluctuations in the concentration of extracellular ATP synchronized with intracellular Ca2+ oscillatory rhythm in cultured cardiac myocytes2007
- Author(s)
  Kawahara, K., Nakayama, Y.
- Journal Title
  
  Chronobiology International 24(6)
  
  Pages: 1035-1048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Possible involvement of nitric oxide in the suppression of the release of cellular ATP during ischemia in cultured cardiac myocytes2007
- Author(s)
  Kawahara, K., Hachiro, T., Matsuyama, D.
- Journal Title
  
  New Horizons in Coronary Artery Disease
  
  Pages: 79-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Possible involvement of ATP-purinoceptor signaling in the intercellular synchronization of intracellular Ca2+ oscillation in cultured cardiac myocytes2007
- Author(s)
  Nakayama, Y., Kawahara, K., Hachiro, T., Yamauchi, Y., Yoneyama, M.
- Journal Title
  
  BioSystems 90
  
  Pages: 179-187
- NAID
  120000966384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300153
[Journal Article] Ischemia/reperfusion-induced death of cardiac myocytes : possible involvement of nitric oxide in the coordination of ATP supply and demand during ischemia.2006
- Author(s)
  Kawahara K. et al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 40(1)
  
  Pages: 35-46
- NAID
  120000960811
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Ischemia/reperfusion-induced death of cardiac myocytes : possible involvement of nitric oxide in the coordination of ATP supply and demand during ischemia.2006
- Author(s)
  Kawahara K., et al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 40(1)
  
  Pages: 35-46
- NAID
  120000960811
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Ruthenium red-induced changes in myocardial energetics during normal beat and ventricular fibrillation in isolated rat hearts.2005
- Author(s)
  Kawahara K. et al.
- Journal Title
  
  The Cardiology 1(2)
  
  Pages: 95-101
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Effect of hypertrophy of myocardial cells on sensitivity against changes in sympathtic nervous tone2005
- Author(s)
  Y.Mizutani, T.Naiki, K.Kawahara
- Journal Title
  
  Proceedings of Symposium on Bio-Medical Engineering 2005 1(CD-ROM)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Contractile function in hypertrophied myocardial cells : Contractile force measurements in myocardial cells using carbon fibers2005
- Author(s)
  Y.Mizutani, T.Naiki, K.Kawahara
- Journal Title
  
  IFMBE proceedings 12(CD-ROM)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocvte co-cultures.2005
- Author(s)
  Kawahara K. et al.
- Journal Title
  
  GLIA 49
  
  Pages: 349-359
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Active tension in hypertrophied myocardial cells2005
- Author(s)
  T.Naiki, Y.Mizutani, K.Kawahara
- Journal Title
  
  Proceedings of the Second Japan-Switzerland Workshop on Biomechanics 1
  
  Pages: 102-102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] 心筋細胞の交感神経活動変化に対する感受性におよぼす細胞肥大化の影響2005
- Author(s)
  水谷祐輔, 内貴猛, 河原剛一
- Journal Title
  
  生体医工学シンポジウム2005講演予稿集 1(CD-ROM)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Contractile function in hypertrophied myocardial cells2005
- Author(s)
  Y.Mizutani, T.Naiki, K.Kawahara
- Journal Title
  
  Proceedings of the International Federation for Medical and Biological Engineering 1(CD-ROM)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Journal Article] Spectral and correlation analyses of the verapamil-induced conversion of ventricular fibrillation to tachycardia in isolated rat hearts.2004
- Author(s)
  Kawahara K. et al.
- Journal Title
  
  Journal of Electrocardiology 37(2)
  
  Pages: 89-100
- NAID
  120000964345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Spectral and correlation analyses of the verapamil-induced conversion of ventricular fibrillation to tachycardia in isolated rat hearts.2004
- Author(s)
  Kawahara K. et al.
- Journal Title
  
  Journal of Electrocardiology 37 (2)
  
  Pages: 89-100
- NAID
  120000964345
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Spectral and correlation analyses of the verapamil-induced conversion of ventricular fibrillation to tachycardia in isolated rat hearts.2004
- Author(s)
  Kawahara, K. et al.
- Journal Title
  
  Journal of Electrocardiology 37
  
  Pages: 89-100
- NAID
  120000964345
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Nitric oxide produced during ischemia is toxic but crucial to preconditioning-induced ischemic tolerance of neurons in culture.2004
- Author(s)
  Kawahara K. et al.
- Journal Title
  
  Neurochemical Research 29
  
  Pages: 797-804
- NAID
  120000956207
- Data Source
  KAKENHI-PROJECT-16300145
[Journal Article] Statistics of Single Cell Mechanics Investigated by Atomic Force Microscopy The
- Author(s)
  S. Hiratsuka, Y. Mizutani, P.G. Cai, M. Tsuchiya, H. Tokumoto, K. Kawahara, T. Okajima
- Journal Title
  
  2010 MRS Spring Meeting Symposium U proceedings
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] Effect of Isoproterenol on Local Contractile Behaviors of Rat Cardiomyocytes Measured by Atomic Force Microscopy Current
- Author(s)
  Y. Mizutani, K. Kawahara, T. Okajima
- Journal Title
  
  Pharmaceutical Biotechnology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310079
[Journal Article] Attempt to decrease energy utilization in hypertrophied cardiomyoctes by alterating microtubule polymerization
- Author(s)
  Y.Mizutani, T.Naiki, K.Kawahara
- Journal Title
  
  Proceedings of Bio-Medical Engineering (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500297
[Presentation] Universal rheological properties of cells in intermediate states observed in stress relaxation of cell sheets2012
- Author(s)
  M.Tsuchiya, Y.Mizutani, K.Kawahara, T.Okajima
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  サンディエゴコンベンションセンター(米国)
- Year and Date
  2012-02-27
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Power-law rheology of normal and cancer cells investigated by atomic force microscopy2012
- Author(s)
  R. Takahashi, Y. Mizutani, K. Kawahara and T. Okajima
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Negaitive-feedback regulation of ATP release during ischemia in cardiac myocytes2012
- Author(s)
  Kawahara, K. Kunugi, S, Matsuyama, D. and Iwabuchi, S.
- Organizer
  World Congress on Medical Physics & Biomedical Engineering
- Place of Presentation
  Beijing (China), BeijingInternational Conference Center.
- Year and Date
  2012-05-28
- Data Source
  KAKENHI-PROJECT-24650245
[Presentation] Power-law rheology of normal and cancer cells by AFM2012
- Author(s)
  R.Takahashi, Y.Mizutani, K.Kawahara, T.Okajima
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  サンディエゴコンベンションセンター(米国)
- Year and Date
  2012-02-27
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Negative-feedback regulation of ATP release during ischemia in cardiac myocytes.2012
- Author(s)
  Koichi Kawahara
- Organizer
  World Congress on Medical Physics & Biomedical Engineering
- Place of Presentation
  Beijing International Congress Center (中国)
- Data Source
  KAKENHI-PROJECT-22300148
[Presentation] 原子間力顕微鏡を用いた物理刺激による細胞カルシウム応答測定2011
- Author(s)
  佐藤淳平,水谷祐輔,河原剛一,岡嶋孝治
- Organizer
  第58回応用物理学関係連合講演会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Positive-feedback regulation loop for the loss of cell division and binucleation shortly after birth in cardiomyocytes2011
- Author(s)
  Kawahara, K., Matsuyama, D.
- Organizer
  5^<th> European Congress of IFMBE
- Place of Presentation
  Budapest Congress & World Trade Center (Hungary)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22300148
[Presentation] 原子間力顕微鏡を用いた水平方向の力学刺激による細胞内カルシウム応答測定2011
- Author(s)
  佐藤淳平、水谷祐輔、河原剛一、岡嶋孝治
- Organizer
  第49回生物物理学会年会
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Temporal Variation of Single Cell Rheology Investigated by Atomic Force Microscopy, (2011.12.19-21, Toyo)2011
- Author(s)
  P.G.Cai, Y.Mizutani, K.Kawahara, T. Okajima
- Organizer
  19th International Colloquium on Scanning Probe Microscopy
- Place of Presentation
  洞爺湖万世閣(北海道)
- Year and Date
  2011-12-19
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] AFMによる単一細胞レオロジーの個体差の精密解析2011
- Author(s)
  蔡萍根、水谷祐輔、土屋雅博、河原剛一、岡嶋孝治
- Organizer
  第72回応用物理学会学術講演会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] AFMによる細胞内ネットワーク構造変化に対する細胞粘弾性の研究2011
- Author(s)
  蔡萍根,水谷祐輔,土屋雅博,河原剛一,岡嶋孝治
- Organizer
  第58回応用物理学関係連合講演会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] AFMによる不死化過程における細胞粘弾性の細胞数分布解析2011
- Author(s)
  水谷祐輔,蔡萍根,土屋雅博,河原剛一,岡嶋孝治
- Organizer
  第58回応用物理学関係連合講演会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Power-law rheology of normal and cancer cells investigated by atomic force microscopy2011
- Author(s)
  R. Takahashi, Y. Mizutani, K. Kawahara, T. Okajima
- Organizer
  19th International Colloquium on Scanning Probe Microscopy
- Place of Presentation
  Toyo
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 虚血時における心筋細胞のATP放出制御とそのシグナル伝達機構に関する研究2011
- Author(s)
  功刀聡彦,岩淵禎弘,松山大輔,河原剛一
- Organizer
  MEとバイオサイバネティクス研究会
- Place of Presentation
  東京,玉川大学
- Data Source
  KAKENHI-PROJECT-22300148
[Presentation] Temporal Variation of Single Cell Rheology Investigated by Atomic Force Microscopy2011
- Author(s)
  P.G. Cai, Y. Mizutani, K. Kawahara and T. Okajima
- Organizer
  19th International Colloquium on Scanning Probe Microscopy
- Place of Presentation
  Toyo
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Power-law rheology of normal and cancer cells investigated by atomic force microscopy2011
- Author(s)
  R.Takahashi, Y.Mizutani, K.Kawahara, T.Okajima
- Organizer
  19th International Colloquium on Scanning Probe Microscopy
- Place of Presentation
  洞爺湖万世閣(北海道)
- Year and Date
  2011-12-19
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Spatial and Temporal Dependence of Single Cell Rheology Investigated by Atomic Force Microscopy2011
- Author(s)
  P.G. Cai, Y. Mizutani, M. Tsuchiya, K. Kawahara , and T. Okajima
- Organizer
  Biophysical Society 55th Annual Meeting
- Place of Presentation
  Baltimore
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Rheology of transformed fibroblast cells investigated by atomic force microscopy2010
- Author(s)
  Y. Mizutani, P. G. Cai, M. Tsuchiya, K. Kawahara, and T. Okajima
- Organizer
  日本生物物理学会第48回年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Time and Space Dependent Studies in Cell Rheology by Atomic Force Microscopy2010
- Author(s)
  P.G. Cai, Y. Mizutani, A. Miyaoka, M. Tsuchiya, K. Kawahara, T. Okajima
- Organizer
  18th International Colloquium on SPM
- Place of Presentation
  Atagawa
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 胎児-新生児遷移における酸化ストレスと心筋細胞の分裂能喪失2010
- Author(s)
  河原剛一
- Organizer
  第63回日本酸化ストレス学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21650103
[Presentation] Rheology of Single Cells under Serum Starvation Measured by Atomic Force Microscopy2010
- Author(s)
  Miyaoka, Y. Mizutani, M. Tsuchiya, K. Kawahara and T. Okajima
- Organizer
  18th International Colloquium on SPM
- Place of Presentation
  Atagawa
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Rheology of transformed cells investigated by AFM2010
- Author(s)
  Y. Mizutani, P. G. Cai, M. Tsuchiya, K. Kawahara and T.Okajima
- Organizer
  International Scanning Probe Microscopy Conference Sapporo '10
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] ケージドグルタミン酸への局所的な光照射を用いたin vitro新規脳虚血モデルの開発2010
- Author(s)
  渡辺知晴,岩淵禎弘,河原剛一
- Organizer
  MEとバイオサイバネティクス研究会
- Place of Presentation
  札幌,北海道大学
- Data Source
  KAKENHI-PROJECT-22300148
[Presentation] AFMによる正常細胞から不死化細胞のナノレオロジー測定2010
- Author(s)
  水谷祐輔,蔡萍根,土屋雅博,河原剛一,岡嶋孝治
- Organizer
  第58回レオロジー討論会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 成ラット単離心筋細胞の高頻度電気刺激による細胞内Ca2+およびMg2+のダイナミクス2010
- Author(s)
  五十嵐博之,水谷祐輔,岩淵禎弘,松山大輔,河原剛一
- Organizer
  MEとバイオサイバネティクス研究会
- Place of Presentation
  東京,玉川大学
- Data Source
  KAKENHI-PROJECT-22300148
[Presentation] Statistics of Single Cell Mechanics Investigated by Atomic Force Microscopy2010
- Author(s)
  T. Okajima, S. Hiratsuka, Y. Mizutani, P.G. Cai, M. Tsuchiya, H. Tokumoto and K. Kawahara
- Organizer
  2010 MRS Spring Meeting, San Francisco
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] AFMによる形質転換過程における線維芽細胞の複素弾性率の解析2010
- Author(s)
  水谷祐輔,蔡萍根,宮岡敦史,土屋雅博,春菜ゆかり,河原剛一,岡嶋孝治
- Organizer
  第57回応用物理学関係連合講演会
- Place of Presentation
  平塚
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 原子間力顕微鏡を用いた正常・老化・不死化細胞の力学統計解析2010
- Author(s)
  水谷祐輔,蔡萍根,土屋雅博,河原剛一,岡嶋孝治
- Organizer
  第49回日本生体医工学会北海道支部大会
- Place of Presentation
  札幌
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 原子間力顕微鏡による心筋細胞の拍動挙動の計測2010
- Author(s)
  水谷祐輔,土屋雅博,河原剛一,岡嶋孝治
- Organizer
  第22回バイオエンジニアリング講演会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 細胞周期を同調させた生細胞のAFMレオロジー測定2009
- Author(s)
  宮岡敦史,平塚伸一郎,水谷祐輔,土屋雅博,河原剛一,岡嶋孝治
- Organizer
  第70回応用物理学会学術講演会
- Place of Presentation
  第70回応用物理学会学術講演会,富山
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 原子間力顕微鏡による生細胞レオロジーの時間領域測定2009
- Author(s)
  平塚伸一郎、水谷祐輔、河原剛一、徳本洋志、岡嶋孝治
- Organizer
  第56回応用物理学会講演会
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 原子間力顕微鏡による生細胞レオロジーの時間領域測2009
- Author(s)
  平塚伸一郎、水谷祐輔、河原剛一、徳本洋志、岡嶋孝治
- Organizer
  第56回応用物理学会講演会
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Mechanics of Spontaneously Beating Cardiac Myocytes Investigated by AFM2009
- Author(s)
  Y. Mizutani, D. Matsumaya, S. Hiratsuka, K. Kawahara, H. Tokumoto, T. Okajima
- Organizer
  The Biophysical Society 53nd Annual Meeting
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] Sublethal ischaemia enhances the expression of glucose transporter 3 in cultured astrocytes2009
- Author(s)
  Iwabuchi, S., Kawahara, K.
- Organizer
  19th Annual Meeting of the European Neurological Society
- Place of Presentation
  Milano
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] 低出力超音波パルス刺激が線維芽細胞遊走能に与える影響について2009
- Author(s)
  岩淵禎弘, 松山大輔, 河原剛一
- Organizer
  第48回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] Elasticity of Cardiac Cells on a Microarray under Oxidative Stress Measured by Atomic Force Microscopy. Y. Mizutani, M. Tsuchiya, S. Hiratsuka, K. Kawahara, H. Tokumoto, and T. Okajima2008
- Author(s)
  Mizutani, Y., Tsuchiya, M., Hiratsuka, S., Kawahara, K., Tokumoto, H., Okajima, T.
- Organizer
  International Scanning Probe Microscopy Conference Seattle '08, Seattle, WA, U.S.A.
- Place of Presentation
  International Scanning Probe Microscopy Conference Seattle Meeting program
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] Rhythmic fluctuations in intracellular Mg^<2+> in spontaneously beating cultured cardiac myocytes2008
- Author(s)
  Koichi Kawahara
- Organizer
  14^<th> Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC 2008)
- Place of Presentation
  Reval Hotel Latvia, Riga (Latvia)
- Year and Date
  2008-06-19
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] 互いに孤立した心筋細胞の同期現象 : 細胞間情報伝達の新しいメカニズム2008
- Author(s)
  河原剛一
- Organizer
  第23回犬山不整脈カンファレンス
- Place of Presentation
  福岡
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] 虚血・再灌流によるグリア細胞間カルシウム情報伝達機構の変化2008
- Author(s)
  岩淵禎弘, 河原剛一
- Organizer
  第47回生体医工学会大会
- Place of Presentation
  生体医工学
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] Machanics of cardiac cells under hypertrophy induced by oxidative stress measured with an atomic force microscope(原子間力顕微鏡を用いた酸化ストレスによる細胞肥大過程の力学特性評価)2008
- Author(s)
  Y. Mizutani, M. Tsuchiya, K. Kawahara, T. Okajima
- Organizer
  第47回日本生物物理学会年会,ppS192
- Place of Presentation
  第47回日本生物物理学会年会,徳島市
- Data Source
  KAKENHI-PROJECT-21310079
[Presentation] 異種細胞融合による終末分化心筋細胞・細胞周期リエントリーの可能性2007
- Author(s)
  松山大輔, 河原剛一
- Organizer
  生体医工学
- Place of Presentation
  第46回生体医工学会大会, 仙台
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] Extracellular ATP-purinoceptor signaling for the intercellular synchronization of intracellular calcium oscillation in cultured cardiac myocytes2007
- Author(s)
  Koichi Kawahara
- Organizer
  MEDICON 2007
- Place of Presentation
  University of Ljubljana, Ljubljana (Slovenia)
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-19300153
[Presentation] Force measurements of microarray living cells2007
- Author(s)
  Mizutani, Y., Tsuchiya, M., Hiratsuka, S., Kawahara, K., Tokumoto, H., Okajima, T.
- Organizer
  Proceedings of the 15^<th> International Colloquium on Scanning Probe Microscopy (ICSPM15)
- Place of Presentation
  Atagawa, Japan
- Data Source
  KAKENHI-PROJECT-19300153

1. YAMAUCHI Yoshiko (50230313)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. NAIKI Takeru (40241385)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. NAKAMURA Takao (00142654)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KUDO Nobuki (30271638)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMAMOTO Katsuyuki (10088867)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KUSUNOKI Masataka (80214956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKAHASHI Eiji (30206792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YONEYAMA Mitsuru

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. OKU Yoshitaka (20252512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. OKAJIMA Takaharu (70280998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 37 results
11. SAITOH Tadashi (20454770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMAMOTO Mitsuaki (40004618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKEI Yoshiaki (40188149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AOKI Mamoru (50001871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HARA Tsutomu (00198889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOUSE Noritsugu (80192657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NISHIURA Yasumasa (00131277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HAMAOKA Takafumi (70266518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KAWAHATSU Kiyonori (80026822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. INANAMI Osamu (10193559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 中島崇行 (30333644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWAHARA Koichi 河原 剛一

Research Projects

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Co-Researchers

Ontogenetic and phylogenetic mechanisms involved in the loss of proliferation activity in mammalian cardiomyocytes after birth.Principal Investigator

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Oxidative stress during fetal-neonatal transition and the formation of a positive-feedback loop for the terminal differentiation of mammalian cardiomyocytes.Principal Investigator

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Statistical Analysis of Single Cell Mechanics by Atomic Force Microscopy

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心筋細胞における核分裂と細胞分裂の解離:増殖と肥大のスイッチ機構Principal Investigator

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Coordination and dissociation of nonlinear oscillations in cardiomyocytes : dysfunction of holonic oscillators leading to arrhythmiasPrincipal Investigator

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Discovering mechanisms to generate cardiac remodeling and decrease ischemic tolerance from mechanical inspection

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微小気泡存在下での超音波照射による期外収縮発生の機序:培養心室筋細胞を用いた検討

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Development of an instrument for temporal and spatial analyses of distribution of muscle oxygenation using near-infrared spectroscopy and its applications

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Hierarchical Correlation Dynamics among Cellular Rhythms: Coordination and Dissociation of Non-linear Biological Oscillators.Principal Investigator

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ミトコンドリアによる心室頻拍-心室細動マクロダイナミクス遷移の制御Principal Investigator

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Experimental verification of causal relationships between measurements of near-infrared spectroscopy and mechanisms of oxygen transport to skeletal muscles

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Ischemia-induced remodeling of the heart : macro- and micro-systems approach to heart functionPrincipal Investigator

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Nonlinear dynamics of heart beat rhythm during ischemia / reperfusion and death of cardiac myocytes.Principal Investigator

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KAWAHARA Koichi 河原剛一