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IMAGAWA Toshiaki  今川 敏明

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TOSHIAKI Imagawa  今川 敏明

今川 敏明

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Researcher Number 20142177
Other IDs
Affiliation (based on the past Project Information) *help 2021: 北海道大学, 理学研究院, 特任准教授
2018: 北海道大学, 理学研究院, 特任准教授
2017: 北海道大学, 理学研究科, 准教授
2014: 北海道大学, 大学院理学研究院, 准教授
2013 – 2014: 北海道大学, 理学(系)研究科(研究院), 准教授 … More
2013: 北海道大学, 理学研究科, 准教授
2009 – 2012: 北海道大学, 大学院・理学研究院, 准教授
2011: 北海道大学, 理学研究科, 准教授
2007 – 2009: Hokkaido University, 大学院・先端生命科学研究院, 准教授
2006: 北海道大学, 大学院先端生命科学研究院, 助教授
2005: Hokkaido Univ., Faculty of Sci., Associate Prof. (2003-2006), 大学院理学研究科(平成15〜17年度), 助教授
2003 – 2005: 北海道大学, 大学院・理学研究科, 助教授
1996 – 2001: 北海道大学, 大学院・理学研究科, 助教授
1998: 北海道大学, 大学院理学研究科, 助教授
1991: National Cardiovascular Center Research Institute Department of Molecular Physio, 循環分子生理部, 室長
1990: 国立循環器病センター研究所, 循環分子生理部, 室員
1988: 国立循環器病センター, 研究所・循環分子生理部, 室員
1987: 国立循環器病センター研究所, 循環分子生理部, 室員 Less
Review Section/Research Field
Principal Investigator
Functional biochemistry / Functional biochemistry
Except Principal Investigator
Functional biochemistry / Living organism molecular science / Basic veterinary science/Basic zootechnical science / Science and Engineering / Circulatory organs internal medicine / Structural biochemistry / Biological Sciences / Veterinary medical science / Basic Section 42020:Veterinary medical science-related
Keywords
Principal Investigator
Na / K-ATPase / タンパク質間相互作用 / 無細胞タンパク質合成系 / c-SRC / 無細胞たんぱく質合成 / 膜タンパク質 / P型ATPase / イオン輸送 / エネルギー変換 … More / 蛍光タンパク質 / p53 / 四量体形成ドメイン / 無細胞タンパク質合成 / cDNAライブラリー / 癌抑制タンパク質 / 蛍光エネルギー移動 / ピューロマイシン / 蛍光融合タンパク質 / 自己切断型リボザイム / Puromycin / Two-hybrid / H, K-ATPase / チロシンキナーゼ / チロシンフォスファターゼ / プロテインキナーゼC / プロテインフォスファターゼ1 / 胃 / 酸分泌 / H,K-ATPase / H^+,K^+-ATPase / プロトンポンプ / PKC / 壁細胞 / リン酸化 / H^+, K^+-ATPase / tyrosine kinase / protein Kinase C / protein phosphatase 1 / tyrosine phosphatase / stomach / acid secretion … More
Except Principal Investigator
リン酸化 / オリゴマー / Na / Naポンプ / Hポンプ / フォスファターゼ / キナーゼ / チロシンキナーゼ / K-ATPase / 疼痛 / 侵害受容体 / phosphorylation / H / セリンキナーゼ / カルシウム / 変異体 / フォールディング / 癌抑制タンパク質 / 蛋白質 / 癌 / 生体分子 / ペプチド / TRPV1 / capsaicin / パッチクランプ / 知覚神経細胞 / ヒスタミン / 遺伝子クローニング / 薬理 / Caイメージング / TRPA1 / TRPチャネル / dephosphorylation / protein kinase / protein phosphatases / H-pump / H,K-ATPase / Kポンプ / oligomer / H^+,K^-ATPase / H^+,K-ATPase / がん抑制タンパク質 / ヘテロオリゴマー / 構造安定性 / アミロイド / β構造 / 蛍光 / 変性 / 構造活性相関 / バイオテクノロジー / フォールデイング / ion channel / intracellular Ca / pain / カプサイシン / 細胞内Ca / メチルサリチル酸 / 鎮痛 / 細胞内Ca濃度 / TRPV1欠損マウス / バニロイド / ナトリウムイオン / 痛覚過敏 / マスタードオイル / シグナル伝達 / 系統進化 / 進化 / 疼痛反応 / 炎症性疼痛 / 知覚神経 / 痛み / 遺伝子発現 / Ca-imaging / 熱感受性 / 変異チャネル / 細胞内Caイメージング / Xenopus Tropicalis / ポリモーダル受容体 / 生物活性 / 多量体化 / 配向化 / ナノマテリアル / バイオミネラリゼーション / 心筋小胞体Caポンプ / 心筋形質膜Caポンプ / CaATPase / 心筋Naポンプ / Na.KATPase / 心筋形質膜 / CaポンプATPase / Cキナーゼ / リアノジンリセプター / モノクローナル抗体 / 心筋小胞体 / Caチャネル / cDNAクロ-ニング / プロティンキナ-ゼ / リアノジン / カルモジュリン / CHO細胞 / Cardicac sarcoplasmic reticulum / Ca channel / cDNA cloning / Protein Kinase / Phosphorylation / Ryanodine / Calmodulin / CHO cells / H,K‐ATPase / プロテインキナーゼC / 胃壁H^+ポンプ / ATPase / 脱リン酸化 / カルシウムイオン / Na^+ポンプ / P型ポンプ / Post-Albers機構 / テトラプロトマー / 構造変化 / P-Type ATPase / Post Albers Scheme / tetraprotomer / フォスタファーゼ / K-ATpase / phosphatases / kinase / ナトリウムポンプ / 蛍光プローブ / 1分子観察 / プロトンポンプ / Sodium Pump / Fluorescent Probe / Single-molecule observation / Proton Pump / 内因性イオウ化合物 / イオンチャネル / チャネル / 侵害受容 Less
  • Research Projects

    (22 results)
  • Research Products

    (93 results)
  • Co-Researchers

    (26 People)
  •  Elucidation of pathological pain via nociceptors and its application to pain relief

    • Principal Investigator
      OHTA Toshio
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Tottori University
  •  Involvement of nociceptive channels as molecular basis of neuropathic pain development

    • Principal Investigator
      Ohta Toshio
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Tottori University
  •  Control of Bioreaction via Oligomerization and Orientation of Tumor Suppressor Protein p53 Tetramer

    • Principal Investigator
      SAKAGUCHI Kazuyasu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Hokkaido University
  •  Elucidation of molecular mechanisms of pathophysiological pain via nociceptive channels and establishment of pain-evaluating system

    • Principal Investigator
      OHTA Toshio
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Tottori University
  •  Stability Change of Tetrameric Structure of Tumor Suppressor Protein p53 in Mutation and Evolution, and Threshold for Loss of Tumor Suppressor Activity in Terms of Disruption of the Tetrameric Structure.

    • Principal Investigator
      SAKAGUCHI Kazuyasu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Hokkaido University
  •  Analysis of molecular mechanisms of neuropathic pain and neciceptive signaling

    • Principal Investigator
      OHTA Toshio
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Tottori University
      Hokkaido University
  •  p53ホモ四量体形成ミュータントの探索-新規タンパク質間相互作用検出系の創出Principal Investigator

    • Principal Investigator
      今川 敏明
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Hokkaido University
  •  Inactivation of Tumor Suppressor Protein p53 by Mutations in the Tetramerization Domain and Stabilizing Methods for the Tetrameric Structure

    • Principal Investigator
      SAKAGUCHI Kazuyasu
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Hokkaido University
  •  Regulatory mechanisms of vanilloid receptor on pain signaling

    • Principal Investigator
      OHTA Toshio
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Tottori University
      Hokkaido University
  •  がん抑制タンパク質p53の四量体形成ドメインのフォールディング

    • Principal Investigator
      SAKAGUCHI Kazuyasu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  P型イオンポンプの無細胞タンパク質合成系を用いた発現法の開発と多量体形成機構Principal Investigator

    • Principal Investigator
      今川 敏明
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Hokkaido University
  •  Investigation of reaction mechanism and higher oligomeric structure of Na-pump based on single-molecule observation technique.

    • Principal Investigator
      KAYA Shunji
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  内因性プロテインキナーゼフォスファターゼによるイオンポンプ触媒鎖の可逆性リン酸化

    • Principal Investigator
      谷口 和弥
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Hokkaido University
  •  Oligomer structure and functional regulation in cation pumps

    • Principal Investigator
      TANIGUCHI Kazuya
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Functional biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Role of Multiple Phosphorylation in Monovalent Cation Transport ATPases

    • Principal Investigator
      TANIGUCHI Kazuya
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  内因性キロキナーゼ・フォスタファターゼ系によるP型ポンプの可逆的リン酸化とイオン輸送

    • Principal Investigator
      TANIGUCHI Kazuya
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  新たに見出した1価陽イオンポンプ触媒鎖N末端の多重リン酸化の意義解明の糸口

    • Principal Investigator
      谷口 和弥
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Hokkaido University
  •  Regulation of H^+-pump in Stomach by Protein PhosphorylationPrincipal Investigator

    • Principal Investigator
      IMAGAWA Toshiaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  ROLE OF THE NOVEL PHOSPHOLYLATION IN TRANSPORT PUMPS

    • Principal Investigator
      TANIGUCHI Kazuya
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Functional biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Reaction mechanism of sarcoplasmic reticulum calcium release channels

    • Principal Investigator
      SHIGEKAWA Munekazu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      National Cardiovascluar Center Research Institute
  •  心筋細胞内Caイオンの動態に関する研究

    • Principal Investigator
      重川 宗一
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cardiovascular Center Research Institute
  •  心筋細胞内Caイオンの動態に関する研究

    • Principal Investigator
      SHIGEKAWA Munekazu
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Cardiovascular Center Research Institute

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 Other

All Journal Article Presentation

  • [Journal Article] Involvement of transient receptor potential A1 channel in algesic and analgesic actions of the organic compound limonene.2016

    • Author(s)
      Kaimoto T, Hatakeyama Y, Takahashi K, Imagawa T, Tominaga M, Ohta T
    • Journal Title

      Eur J Pain

      Volume: In press

    • DOI

      10.1002/ejp.840

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26292150
  • [Journal Article] Quantitative Analysis of p53 Hetero-tetramers for Dominant Negative Effect in Transcriptional Activity2015

    • Author(s)
      Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Peptide Sci.

      Volume: 2014 Pages: 181-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Journal Article] Heat and noxious chemical sensor, chicken TRPA1, as a target of bird repellents and identification of its structural determinants by multispecies functional comparison2014

    • Author(s)
      Saito S, Banzawa N, Fukuta N, Takahashi K, Imagawa T, Ohta T, Tominaga M
    • Journal Title

      Mol Biol Evol

      Volume: 31(3) Pages: 708-722

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Journal Article] Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori.2014

    • Author(s)
      Saito S, Banzawa N, Fukuta N, Saito T.C., Takahashi K, Imagawa T, Ohta T, Tominaga M.
    • Journal Title

      Mol Biol Evol

      Volume: 31(3) Pages: 708-22

    • DOI

      10.1093/molbev/msu001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25670290, KAKENHI-PROJECT-25860172, KAKENHI-PROJECT-26292150
  • [Journal Article] Molecular Basis Determining Inhibition/Activation of Nociceptive Receptor TRPA1: A Single Amino Acid Dictates Species-specific Actions of the Most Potent Mammalian TRPA1 Antagonists.2014

    • Author(s)
      Banzawa N1, Saito S2, Imagawa T., Kashio M., Takahashi K., Tominaga M. and Ohta T.
    • Journal Title

      J Biol Chem

      Volume: 289 Pages: 31927-31939

    • DOI

      10.1074/jbc.m114.586891

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24580426, KAKENHI-PROJECT-25860172, KAKENHI-PROJECT-26292150
  • [Journal Article] Involvement of TRPA1 activation in acute pain induced by cadmium in mice2013

    • Author(s)
      Miura S, Takahashi K, Imagawa T, Uchida K, Saito S, Tominaga M, Ohta T.
    • Journal Title

      Molecular Pain

      Volume: 9 Pages: 7-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Journal Article] Involvement of TRPA1 activation in acute pain induced by cadmium in mice.2013

    • Author(s)
      Miura S, Takahashi K, Imagawa T, Uchida K, Saito S, Tominaga M, OhtaT
    • Journal Title

      Mol. Pain

      Volume: 9 Pages: 7-7

    • DOI

      10.1186/1744-8069-9-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380160, KAKENHI-PROJECT-24580426
  • [Journal Article] H2S functions as a nociceptive messenger through transient receptor potential ankyrin 1 (TRPA1) activation.2012

    • Author(s)
      Ogawa H, Takahashi K, Miura S, Imagawa T, Saito S, Tominaga M, Ohta T
    • Journal Title

      Neuroscience

      Volume: (in press) Pages: 335-343

    • DOI

      10.1016/j.neuroscience.2012.05.044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21658096, KAKENHI-PROJECT-22380160, KAKENHI-PROJECT-24580426
  • [Journal Article] Repression of p53transcriptional activity by inhibitory peptide via heterotetramerization2012

    • Author(s)
      J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Peptide Sci.

      Volume: 2011 Pages: 301-302

    • NAID

      10030204437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Molecular Cloning and Functional Characterization of Xenopus tropicalis Frog Transient Receptor Potential Vanilloid 1 Reveal Its Functional Evolution for Heat, Acid, and Capsaicin Sensitivities in Terrestrial Vertebrates2012

    • Author(s)
      Ohkita M, Saito S, Imagawa T, Takahashi K, Tominaga M, Ohta T
    • Journal Title

      Journal of Biological Chemistry

      Volume: 287 Pages: 1806-1816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21658096
  • [Journal Article] Molecular Cloning and Functional Characterization of Xenopus tropicalis Frog Transient Receptor Potential Vanilloid 1 Reveal Its Functional Evolution for Heat, Acid, and Capsaicin Sensitivities in Terrestrial Vertebrates.2012

    • Author(s)
      Ohkita M, Saito S, Imagawa T, Takahashi K, Tominaga M, Ohta T
    • Journal Title

      Journal of Biological Chemistry

      Volume: 287(4) Pages: 1806-1816

    • DOI

      10.1074/jbc.m111.305698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21658096, KAKENHI-PROJECT-22380160, KAKENHI-PROJECT-22791164
  • [Journal Article] H2S functions as a nociceptive messenger through transient receptor potential ankyrin 1 (TRPA1)activation2012

    • Author(s)
      Ogawa H, Takahashi K, Miura S,Imagawa T, Saito S, Tominaga M, Ohta T
    • Journal Title

      Neuroscience

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21658096
  • [Journal Article] Analysis of Transient Receptor Potential Ankyrin 1 (TRPA1) in Frogs and Lizards Illuminates Both Nociceptive Heat and Chemical Sensitivities and Coexpression with TRP vanilloid 1 (TRPV1) in Ancestral Vertebrates2012

    • Author(s)
      Saito S, Nakatsuka K, Takahashi K, Fukuta N, Imagawa T, Ohta T, Tominaga M.
    • Journal Title

      J Biol Chem

      Volume: 287(36) Pages: 30743-30754

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Journal Article] Development of screening system for tumor suppressor p53 activators and inhibitors2012

    • Author(s)
      K. Uesugi, S. Ohshima, A. Tanaka, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Peptide Sci.

      Volume: 2011 Pages: 345-346

    • NAID

      10030204653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerization2012

    • Author(s)
      J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Bioorg Med Chem. Lett.

      Volume: 22 Pages: 2780-2783

    • DOI

      10.1016/j.bmcl.2012.02.085

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133, KAKENHI-PROJECT-23651210
  • [Journal Article] Molecular Cloning and Functional Characterization of Xenopus Molecular Cloning and Functional Characterization of Xenopus tropicalis Frog Transient Receptor Potential Vanilloid 1 Reveal Its Functional Evolution for Heat, Acid, and Capsaicin Sensitivities in Terrestrial Vertebrates2012

    • Author(s)
      Ohkita M, Saito S, Imagawa T, Takahashi K, Tominaga M, Ohta T.
    • Journal Title

      J Biol Chem

      Volume: 287(4) Pages: 2388-2397

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Journal Article] H2S functions as a nociceptive messenger through transient receptor potential ankyrin 1 (TRPA1) activation2012

    • Author(s)
      Ogawa H, Takahashi K, Miura S, Imagawa T, Saito S, Tominaga M, Ohta T
    • Journal Title

      Neuroscience

      Volume: 218 Pages: 335-343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Journal Article] Low Threshold of Destabilization for Loss of Tumor Suppressor Activity of p53 : A Quantitative Analysis of p53 Tetramerization Domain Mutants2011

    • Author(s)
      R. Kamada, T. Nomura, Y. Chuman, T.Imagawa C.W. Anderson, and K. Sakaguchi
    • Journal Title

      Peptide Sci

      Volume: 2010 Pages: 149-150

    • NAID

      10028237634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Repression of p53 transcriptional activity by p53 tetramerization domain peptide containing PTD and NLS domain2011

    • Author(s)
      J. Wada, R. Kamada, Y. Chuman, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Peptide Sci.

      Volume: 2010 Pages: 95-96

    • NAID

      10028237399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Inhibition of p53 by Introducing Tetramerization Domain Peptide Fused with Polyvalent Cationic Sequence into cells2010

    • Author(s)
      R. Kamada, S. Ohshima, Y. Chuman, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Peptide Sci.

      Volume: 2009 Pages: 319-320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Histamine potentiates acid-induced responses mediating transient receptor potential VI (TRPV1) in mouse primary sensory neurons.2010

    • Author(s)
      Kajihara Y, Murakami M, Imagawa T, Otsuguro K, Ito S, Ohta T
    • Journal Title

      Neuroscience 166

      Pages: 292-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Histamine potentiates acid-induced responses mediating transient receptor potential V1 (TRPV1) in mouse primary sensory neurons.2010

    • Author(s)
      Kajihara Y, Murakami M, Imagawa T, Otsuguro K, Ito S, Ohta T.
    • Journal Title

      Neuroscience 166(1)

      Pages: 292-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Biomineralization Activity of Multivalent min TBP-1 Peptide Mediated by p53 Tetramerization Domain2010

    • Author(s)
      T. Sakaguchi, R. Kamada, T. Nomura, Y. Chuman, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Peptide Sci.

      Volume: 2009 Pages: 411-412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Histamine potentiates acid-induced responses mediating transient receptor potential V1(TRPV1) in mouse primary sensory neurons2010

    • Author(s)
      Kajihara Y, Murakami M, Imagawa T, Otsuguro K, Ito S, Ohta T
    • Journal Title

      Neuroscience

      Volume: 166(1) Pages: 292-304

    • DOI

      10.1016/j.neuroscience.2009.12.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21658096
  • [Journal Article] Evaluation of Transcriptional Activity of p53 in Individual Living Mammalian Cell2009

    • Author(s)
      T.Imagawa, T. Terai, Y. Yamada, R. Kamada and K. Sakaguchi
    • Journal Title

      Anal. Biochem. 387

      Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Involvement of transient receptor potential vanilloid subtype 1(TRPV1) in analgesic action of methylsalicylate.2009

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      Mol.Pharmacol. 75

      Pages: 307-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Involvement of transient receptor potential vanilloid subtype 1 (TRPV1) in analgesic action of methylsalicylate.2009

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      Mol. Pharmacol 75

      Pages: 307-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Effects of tumor-associated mutations in the p53 tetramerization domain on oligomerization state and transcriptional activity2009

    • Author(s)
      R. Kamada, T. Terai, T. Nomura, Y. Chuman, T. Imagawa, and K. Sakaguchi
    • Journal Title

      Adv Exp Med Biol

      Volume: 611 Pages: 567-8

    • DOI

      10.1007/978-0-387-73657-0_249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Journal Article] Effects of tumor-associated mutations in thep53 tetramerization domain onoligomerization state and transcriptionalactivity2009

    • Author(s)
      R. Kamada, T. Terai, T. Nomura, Y. Chuman, T. Imagawa, K. Sakaguchi
    • Journal Title

      Adv. Exp.Med. Biol 611

      Pages: 567-568

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Involvement of transient receptor potential vanilloid subtype 1 (TRPV1) in analgesic action of methylsalicylate2009

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      Mol. Pharmacol 75

      Pages: 307-317

    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Involvement of transient receptor potential vanilloid subtype1(TRPV1)in analgesic action of methylsalicylate2009

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      Mol.Pharmacol. 75

      Pages: 307-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Evaluation of Transcriptional Activity of p53 in Individual Living Mammalian Cell2009

    • Author(s)
      Imagawa, T, Terai, T., Yamada, Y., Kamada. R.. and Sakaguchi, K.
    • Journal Title

      Anal. Biochem 387

      Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19657037
  • [Journal Article] Evaluation of transcriptional activity of p53 in individual living mammalian cells2009

    • Author(s)
      T. Imagawa
    • Journal Title

      Anal. l Biochem. 387

      Pages: 249-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Correlation between Expression Level in E.coli and Stability of Oligomeric Structure ofthe p53 Tetramerization Domain2008

    • Author(s)
      H. Miyazaki, R. Kamada, T. Nomura, Y. Chuman, T.Imagawa and K. Sakaguchi
    • Journal Title

      Peptide Sci 2007

      Pages: 317-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Novel gating and sensitizing mechanism of capsaicin receptor (TRPV1) : Tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV12008

    • Author(s)
      Ohta T. Imagawa T, Ito S.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 9377-9387

    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Structural Photomodulation of Peptides with Azobenzoate Derivative in Peptide Backbone.2008

    • Author(s)
      R. Kamada, K. Fukuda, H. Miyazaki, T.Nomura, Y. Chuman, T. Imagawa, K. Tanino and K. Sakaguchi
    • Journal Title

      Peptide Sci 2007

      Pages: 447-448

    • NAID

      10021907298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Correlation of Oligomeric Structure and Transcriptional Activity of p53 Mutants2008

    • Author(s)
      R. Kamada, T. Terai, T. Nomura, Y. Chuman, T.Imagawa and K. Sakaguchi
    • Journal Title

      Peptide Sci 2007

      Pages: 69-70

    • NAID

      10021906623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Novel gating and sensitizing mechanism of capsacin receptor(TRPV1) : Tonic inhibitory rugulation of extracellular sodium through the external protonation sites on TRPV12008

    • Author(s)
      Ohta T, Imagawa T., Ito S.
    • Journal Title

      J.Biol.Chem. 283

      Pages: 9377-9387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Novel gating and sensitizing mechanism of capsacin receptor(TRPV1): Tonic inhibitory rugulation of extracellular sodium through the external protonation sites on TRPV1.2008

    • Author(s)
      Ohta T, Imagawa T. & Ito S.
    • Journal Title

      Journal of Biological Chemistry 283

      Pages: 9377-9387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Novel gating and sensitizing mechanism of capsaicin receptor (TRPV 1): Tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV1.2008

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 9377-9387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Novel agonistic action of mustard oil on recombinant and endogenous porcine Transient Receptor Potential V1(pTRPV1) channels.2007

    • Author(s)
      Ohta T, Imagawa T. and Ito S
    • Journal Title

      Biochemical Pharmacology 73

      Pages: 646-656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Novel agonistic action of mustard oil on recombinant and endogenous porcine Transient Receptor Potential V1 (pTRPV 1) channels.2007

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      Biochem. Pharmacol 73

      Pages: 646-656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Novel agonistic action of mustard oil on recombinant and endogenous porcine Transient Receptor Potential VI (pTRPV1) channels2007

    • Author(s)
      Ohta T, Imagawa T, Ito S.
    • Journal Title

      Biochem. Pharmacol 73

      Pages: 646-656

    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Thermodynamic Stability of Mutant p53 Tetramerization Domain Peptides Associated with Human Tumors2007

    • Author(s)
      R. Kamada, T. Nomura, Y. chuman, T. Imagawa and K. Sakaguchi
    • Journal Title

      Peptide Sci 2006

      Pages: 131-132

    • NAID

      10020530042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Fibrillar and Granular Aggregation of G334V Mutant p53 Tetramer Peptide. Y. Asanomi, Y. Higashimoto2006

    • Author(s)
      Y. Asanomi, Y. Higashimoto, Y. Chuman, S. Kaya, T. Imagawa and K. Sakaguchi
    • Journal Title

      Peptide Sci 2005

      Pages: 397-398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Journal Article] Thr-774(Transmembrane Segment M5), Val-920(M8), and Glu-954(M9)are involved in Na+ Transport, and Gln-923(M8)is essential for Na, K-ATPase activity.2006

    • Author(s)
      Imagawa, T.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 18736-18744

    • Data Source
      KAKENHI-PROJECT-16041202
  • [Journal Article] Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-hydroxytryptamine receptors in rat primary sensory neurons2006

    • Author(s)
      Ohta T, Ikemi Y, Murakami M, Imagawa T, Otsuguro K, Ito S.
    • Journal Title

      J. Physiol 576

      Pages: 809-822

    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-hydroxytryptamine receptors in rat primary sensory neurons.2006

    • Author(s)
      Ohta T, Ikemi Y, Murakami M, Imagawa T, Otsuguro K, Ito S.
    • Journal Title

      J. Physiol 576

      Pages: 809-822

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Journal Article] Thr-774 (Transmembrane Segment M5), Val-920 (M8), and Glu-954 (M9) Are Involved in Na+ Transport, and Gln-923 (M8) Is Essential for Na, K-ATPase Activity.2005

    • Author(s)
      T.Imagawa et al.
    • Journal Title

      J. Biol. Chem. 280

      Pages: 18736-18744

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13142201
  • [Journal Article] Thr-774 (Transmembrane Segment M5), Val-920 (M8), and Glu-954 (M9) Are Involved in Na^+ Transport, and GIn-923 (M8) Is Essential for Na,K-ATPase Activity.2005

    • Author(s)
      T.Imagawa
    • Journal Title

      The Journal of Biological Chemistry 280

      Pages: 18736-18744

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13142201
  • [Journal Article] Transmembrane Segment M5),Val-920 (M8), and Glu-954 (M9) Are Involved in Na^+ Transport, and Gln-923 (M8) Is Essential for Na, K-ATPase Activivy2005

    • Author(s)
      T.Imagawa
    • Journal Title

      The Journal of Biological Chemistry 280

      Pages: 18736-18744

    • Data Source
      KAKENHI-PROJECT-13142201
  • [Journal Article] The Thr-774 (Transmembrane Segment M5), Val-920 (M8) and Glu-954 (M9) are Involved in Na+ Transport and Gln-923 (M8) is Essential for Na/K-ATPase Activity.2005

    • Author(s)
      Imagawa, T
    • Journal Title

      J.Biol.Chem. 280

      Pages: 18736-18744

    • Data Source
      KAKENHI-PROJECT-16657033
  • [Journal Article] The amino acid sequence G442DASE446 in Na/K-ATPase is an important motif in forming high and low affinity ATP binding pocket.2003

    • Author(s)
      T.Imagawa
    • Journal Title

      The Journal of Biological Chemistry 278

      Pages: 50283-50292

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13142201
  • [Journal Article] The amino acid sequence G442DASE446 in Na/K-ATPase is an important motif in forming high and low affinity ATP binding pocket.2003

    • Author(s)
      T.Imagawa et al.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 50283-50292

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13142201
  • [Presentation] p53ヘテロ多量体形成および転写活性化能の細胞内定量的解析系の構築2014

    • Author(s)
      菅野まどか、今川敏明、戸口侑、鎌田瑠泉、坂口和靖
    • Organizer
      日本生化学会北海道支部第51回支部例会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-07-18
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Re-evaluation the Transcriptional Activity of p53 Hetero-tetramers for Dominant Negative Effect2014

    • Author(s)
      Y. Toguchi, M. Kanno, T. Imagawa and K. Sakaguchi
    • Organizer
      2nd Intennational Symposium on Ambitious Leader's Program
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Cadmium induces acute pain through the activation of nociceptive TRPA1 channel in mice.2013

    • Author(s)
      Ohta T, Miura S, Takahashi K, Imagawa T, Uchida K, Saito S, Tominaga M
    • Organizer
      Neuro2013
    • Place of Presentation
      京都 国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Presentation] Cadmium induces acute pain through the activation of nociceptive TRPA1 channel in mice2013

    • Author(s)
      Ohta T, Miura S, Takahashi K, Imagawa T, Uchida K, Saito S, Tominaga M.
    • Organizer
      Neuro2013
    • Place of Presentation
      Kyoto
    • Year and Date
      2013-06-20
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Presentation] Monitoring system of endogenous p53-depndent transcriptional activity in living cells2011

    • Author(s)
      T. Imagawa, et al
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Presentation] ニシツメガエルTransient receptor potential vanilloid1は侵害刺激を受容する2011

    • Author(s)
      大北真嗣, 齋藤 茂, 富永真琴, 高橋賢次, 今川敏明, 太田利男
    • Organizer
      第7回TRP チャネル研究会
    • Place of Presentation
      岡崎
    • Year and Date
      2011-06-20
    • Data Source
      KAKENHI-PROJECT-22380160
  • [Presentation] Monitoring system of endogenous p53-depndent transcriptional activity in living cells2011

    • Author(s)
      T.Imagawa
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Presentation] 生細胞蛍光イメージングを利用した癌抑制タンパク質p53 の機能解析2011

    • Author(s)
      T. Imagawa, et al
    • Organizer
      第48回日本生化学会北海道支部例会
    • Place of Presentation
      札幌医科大学(札幌市)
    • Year and Date
      2011-08-05
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Presentation] 生細胞蛍光イメージングを利用した癌抑制タンパク質p53の機能解析2011

    • Author(s)
      T.Imagawa
    • Organizer
      第48回日本生化学会北海道支部例会
    • Place of Presentation
      札幌医科大学(札幌市)
    • Year and Date
      2011-08-05
    • Data Source
      KAKENHI-PROJECT-21310133
  • [Presentation] MethylsalicylateによるTransient Receptor Potential Vanilloid1(TRPV1)活性化と鎮痛作用について2010

    • Author(s)
      太田利男, 今川敏明, 伊藤茂男
    • Organizer
      第149回日本獣医学会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Xenopus Tropicalis TRPV1遺伝子クローニングと発現・機能解析2010

    • Author(s)
      大北真嗣、齋藤茂、今川敏明、高橋賢次、太田利男
    • Organizer
      第150回日本獣医学会学術集会
    • Place of Presentation
      帯広
    • Year and Date
      2010-09-16
    • Data Source
      KAKENHI-PROJECT-21658096
  • [Presentation] MethylsalicylateによるTransient Receptor Potential Vanilloid1(TRPV1)活性化と鎮痛作用について2010

    • Author(s)
      太田利男、今川敏明、伊藤茂男
    • Organizer
      第149回日本獣医学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21658096
  • [Presentation] Activation of transient receptor potential vanilloid 1 (TRPV1) by methylsalicylate2010

    • Author(s)
      Ohta T.Imagawa T.Ito S.
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] MethylsalicylateによるTransient Receptor Potential Vanilloid1 (TRPV1)活性化と鎮痛作用について2010

    • Author(s)
      太田利男、今川敏明、伊藤茂男
    • Organizer
      第149回日本獣医学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Activation of transient receptor potential vanilloid 1 (TRPV1) by methylsalicylate2010

    • Author(s)
      Ohta T., Imagawa T., Ito S.
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21658096
  • [Presentation] メチルサリチル酸によるTRPV1活性化作用について2010

    • Author(s)
      太田利男, 今川敏明, 伊藤茂男
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] TRPV1チャネルの細胞外ナトリウムイオンによる活性調節2008

    • Author(s)
      太田利男、今川敏明、伊藤茂男
    • Organizer
      第4回TRPチャネル研究会
    • Place of Presentation
      生理学研究所(岡崎)
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] TRPVlチャネルの細胞外ナトリウムイオンによる活性調節2008

    • Author(s)
      太田利男、今川敏明、伊藤茂男
    • Organizer
      第4回TRPチャネル研究会
    • Place of Presentation
      生理学研究所、岡崎カンファレンスセンター
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] がん抑制タンパク質p53のリン酸化部位変異体の転写活性と安定性2008

    • Author(s)
      今川敏明、大島祥吾、坂口和靖
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19657037
  • [Presentation] TRPV1チャネルの細胞外ナトリウムイオンによる活性調節2008

    • Author(s)
      太田利男, 今川敏明, 伊藤茂男
    • Organizer
      第4回TRPチャネル研究会
    • Place of Presentation
      岡崎
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Action of allylisothiocyanate on recombinant and endogenous porcine transient receptor potential V1(pTRPV1)channels.2007

    • Author(s)
      T. Ohta, T. Imagawa & S. I to
    • Organizer
      第80回日本薬理学会年会
    • Place of Presentation
      名古屋大学(名古屋)
    • Year and Date
      2007-03-18
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Stability of oligomeric structure is the key factor for transcriptional activity in tumor suppressor protein p532007

    • Author(s)
      今川敏明
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-19657037
  • [Presentation] AllylisothiocyanateによるTRPV1チャンネルに対する活性化作用2007

    • Author(s)
      太田利男, 鳥居優人, 今川敏明, 伊藤茂男
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      江別
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] AllylisothiocyanateによるTRPV1チャンネルに対する活性化作用2007

    • Author(s)
      太田利男、鳥居優人、今川敏明、伊藤茂男
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      酪農学園大(江別)
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Stability of oligomeric structure is the key factor for transcriptional activity in tumor suppressor protein p53 BMB20072007

    • Author(s)
      T. Imagawa, et. al.
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Presentation] AIIylisothiocyanateによるTRPVIチャンネルに対する活性化作用2007

    • Author(s)
      太田利男、鳥居優人、今川敏明、伊藤茂男
    • Organizer
      第144回日本獣医学会
    • Place of Presentation
      酪農大
    • Year and Date
      2007-09-03
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] 太田利男、今川敏明、伊藤茂男(2007) AllylisothiocyanetelこよるTransient Receptor Potential V1(TRPV1)チャンネルに対する刺激作用2007

    • Author(s)
      太田利男, 今川敏明, 伊藤茂男
    • Organizer
      第80回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2007-03-20
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Stability of oligomeric structure is the key factor for transcriptional activity in tumor suppressor protein p532007

    • Author(s)
      今川 敏明
    • Organizer
      BMB2007(第30回日本分子生物学会年会 第80回日本生化学会大会 合同大会)
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Data Source
      KAKENHI-PROJECT-18310140
  • [Presentation] ブタTRPV1遺伝子クローニングと発現機能解析-内因性TRPV1受容体反応との比較-2006

    • Author(s)
      太田利男, 小松竜一, 今川敏明, 乙黒兼一, 伊藤茂男
    • Organizer
      第79回日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-03-20
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Analysis of Stability of Tetrameric Structure and Transcriptional Activity in Evolution of Tumor Suppressor Protein p53

    • Author(s)
      J. Wada, T. Nomura, R. Kamada, T. Imagawa, and K. Sakaguchi
    • Organizer
      Methods in Protein Structure Analysis 2014
    • Place of Presentation
      Base Village Conference Center (U.S.A)
    • Year and Date
      2014-07-27 – 2014-08-01
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Changes of Structural Stability of p53 Tetramerization Domain by Arginine Methylation

    • Author(s)
      J. Wada, R. Kamada, T. Imagawa, and K. Sakaguchi
    • Organizer
      Frontier Chemistry Center the 3rd International Symposium
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-06-13 – 2014-06-14
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] 蛍光レポーターアッセイを用いた定量的解析によるヘテロ四量体p53の転写活性化能

    • Author(s)
      戸口侑、菅野まどか、今川敏明、坂口和靖
    • Organizer
      第79回日本インターフェロンサイトカイン学会学術集会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-06-19 – 2014-06-20
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Effects of p53 Tetramerization Domain Mutants found in Li-Fraumeni Syndrome on Hetero-oligomerization and Transcriptional Activity

    • Author(s)
      M. Kanno, T. Imagawa, Y. Toguchi, R. Kamada, and K. Sakaguchi
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] ブタTRPV1遺伝子クローニングと発現機能解析-w内因性TRPV1受容体反応との比較-(P2N-34)

    • Author(s)
      太田利男、小松竜一、今川敏明、乙黒兼一、伊藤茂男
    • Organizer
      Molecular cloning, functional characterization of the porcine TRPV1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1. J. Pharm. Sci. (100Suppl 1.238P)
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] AllylisothiocyaneteによるTransient ReceptorPotentialV1(TRPV1)チャンネルに対する刺激作用

    • Author(s)
      太田利男、今川敏明、伊藤茂男
    • Organizer
      第80回日本薬理学会年会(Action of allylisothiocyanate on recombinant and endogenous porcine transient receptor potential V1 (pTRPV1) channels. J. Pyarmacol. Sci. 103, Supple 1.256p)
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18380171
  • [Presentation] Destabilization of p53 Tetramer Formation by Arginine Methylation

    • Author(s)
      J. Wada, R. Kamada, T. Imagawa, and K. Sakaguchi
    • Organizer
      the 10th Nanjing-Hokkaido-NIMS/MANA Joint Symposium
    • Place of Presentation
      ルスツリゾート(北海道)
    • Year and Date
      2014-08-22 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Quantitative Analysis of p53 Hetero-tetramers for Dominant Negative Effect in Transcriptional Activity

    • Author(s)
      Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
    • Organizer
      第51回ペプチド討論会
    • Place of Presentation
      徳島大学(徳島市)
    • Year and Date
      2014-10-22 – 2014-10-24
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Analysis of p53 Mutation for Dominant Negative Effect in Transcriptional Activity

    • Author(s)
      Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
    • Organizer
      Frontier Chemistry Center the 3rd International Symposium
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2014-06-13 – 2014-06-14
    • Data Source
      KAKENHI-PROJECT-24310152
  • [Presentation] Hetero-oligomerization of the WildI-type and Mutant Tumor Suppessor Protein p53

    • Author(s)
      Y. Toguchi, M. Kanno, T. Imagawa, and K. Sakaguchi
    • Organizer
      5th Symposium on Academic Exchange and Collaborative Research (AECoR-5)
    • Place of Presentation
      ETH Zurich(Switzerland)
    • Year and Date
      2014-11-27 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-24310152
  • 1.  KAYA Shunji (90186023)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  TANIGUCHI Kazuya (40028204)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  OHTA Toshio (20176895)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 50 results
  • 4.  SAKAGUCHI Kazuyasu (00315053)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 26 results
  • 5.  CHUMAN Yoshiro (40372263)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 13 results
  • 6.  TAKAHASHI Kenji (00400143)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 7.  SHIGEKAWA Munekazu (00113738)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  島田 明 (60001848)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  INANAMI Osamu (10193559)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  渡辺 公英 (00093485)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  WILHELM Scho
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  JEFFREY Froe
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  SVEN Mardh
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  NAKAMURA Hiroshi (30029508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SUZUKI Hiroshi (50183421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HAYSHI Yutaro (10086556)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小栗栖 太郎 (70177202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NAKASAKI Yasuaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  POST Robert L
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MARDH Sven
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  FROEHLICH Jeffrey P
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SCHONER Wilhelm
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  FROERHIC Jef
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ALBERS Wayne
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  富永 真琴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  加塩 麻紀子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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