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AZUMA Chihiro  東 千尋

ORCIDConnect your ORCID iD *help
Researcher Number 20151061
Affiliation (based on the past Project Information) *help 2001: 大阪大学, 医学部附属病院, 助教授
2000 – 2001: 大阪大学, 医学部・附属病院, 助教授
1999: Osaka University, Graduate School of Medicine, Lecturer, 医学系研究科, 講師
1997 – 1998: Osaka University Medical School, Lecturer, 医学部, 講師
1992 – 1996: 大阪大学, 医学部, 助手
1988 – 1989: 大阪大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
Keywords
Principal Investigator
dysplasia / genomic lmprinting / telomerase / mol gene / PXGR gene / CIS / テロメアーゼ活性 / モータリン蛋白 / クロナリティー / CIS病変 … More / 子宮頸部上皮内病変 / genomicimprinting現象 / genomic imprinting現象 / テロメラーゼ活性 / mol遺伝子 / PXGR遺伝子 / 異型上皮病変 / 子宮頚部癌 / Gene-targeting / Parturition / Molecular cloning / Oxytocin receptor gene / 遺伝子クローニング / ウェスタンブロッティング / ノーザンブロッティング / 免疫組織染色 / in situハイブリダイゼーション / オキシトシンレセプター / ノックアウトマウス / 分娩 / クローニング / オキシトシン受容体遺伝子 / Macrophage colony-stimulating factor / Mitochondrial DNA / Androgeners / Choriocarcinoma / Hydatidiform mole / DNA fingerprint / c-fms / MCSF / ノ-ザンブロットハイブリダイゼ-ション / サザンブロットハイブリダイゼ-ション / ミニサテライトDNAプロ-ブ / マクロファ-ジコロニ-刺激因子 / ミトコンドリアDNA / 雄性発生 / 絨毛癌 / 胞状奇胎 / DNA指紋 / HVJリポオーム / 遺伝子導入 / 着床 / NFkB … More
Except Principal Investigator
CD46 / oxytocin receptor / 早産 / acrosome reaction / オキシトシン受容体 / 絨毛癌 / HCG / transcription / chorioamnionitis / uterine contraction / methylated DNA / preterm labor / 卵管 / 酸化ストレス / U-Maf / SNRPN / H19 / IGF2 / human spermatozoa / 受精 / 先体反応 / ヒト精子 / HLA-G / RFLP / PCR / 婦人科癌 / Antiphospholipidantibody / Activatedpartial thromboplastin time / Anti-cardiolipinantibody / Heterogeneity / Lupus anticoagulant / Oxytocin receptor / Apoptosis / LIF / IL-6 / Decidua / Trophoblast / モノクローナル抗体 / TIMP / 子宮内膜癌 / Xenopus Oocytes / Invitro translation / Invitro transcription / Invitro metagenesis / CAGY region / Beta subunit / in vitro transcription and transletion / point mutation / ヒト絨毛性ゴナドトロビン / 先天性TSH欠損症 / Enzyme-imonuro assay / アフリカツメガエル卵母細胞 / in vitro transcription / DNAシ-クエンス / in vitro mutagenesis system / Gly→Arg、Asp変換 / アフリカツメガエル / 塩基置換 / α鎖、β鎖、CDNA / ブル-スクリプトベクタ- / CAGY領域 / α鎖、β鎖 / fraclalkine / SLPI / Fallopian tube / protease inhibitor / SLPI(secretory leukocyte elastase inhibitor) / Fractalkine / 精子先体反応 / SLPI (secretory leukocyte elastase inhibitor) / プロテアーゼインヒビター / HNE(4-hysroxy-2-nonenal) / prostaglandin / COX(cyclooxygenase) / HNE(4-hydroxy-2-nonenal) / シクロオキシゲナーゼ / ホスホリパーゼ / アラキドン酸 / 絨毛羊膜炎 / 子宮収縮 / 陣痛 / メチル化DNA / oviduct / prostaglandin D synthetase (PGDS) / oestrogen / endometrium / プロスタグランディン / プロスタグランディンD合成酵素 / 女性ホルモン / 子宮内膜 / ポロスタグランディンD合成酵素 / knockout mice / preterm birth / intrauterine growth retardation (IUGR) / oxidative stress / fetal brain injury / Mut-T / 8-oxoグアニン / ノックアウトマウス / 胎児発育遅延(IUGR) / 胎児中枢神経障害 / fertilization / human oocyte / 受精分子 / ヒト卵 / DNA binding protein / Mammary gland / N-gycosylation pont mutation / 脱感作現象 / 突然変異体 / 遺伝的背景 / 早期発現 / DNA結合蛋白 / 乳腺 / 点突然変異 / 糖鎖修飾部位 / regulatory element / N-glycosylation / oxytocin binding capacity / oxytocin unresponsiveness / ゲルシフトアッセイ / 発見調節領域 / 糖鎖 / 発現調節領域 / オキシトシン結合能 / 遺伝子多型 / オキシトシン不応症 / 遷延分娩 / ovarian choriocarcinoma / human imprinted genes / genomic imprinting / IGF2.H19.SNRPN遺伝子 / HLA-G遺伝子 / ゲノム・インプリント解除 / 胚細胞系腫瘍 / HI9 / 絨毛癌再 / 良性卵巣奇形腫 / ゲノムインプリンティング / bystander killing effect / ganciclovir / thymidine kinase / cervical adenocarcinoma / herpes virus / endometrial cancer / gene therapy / バイスタンダー効果 / ガンシクロビル / チミヂンキナーゼ / ヘルペスウイルス / 遺伝子治療 / 子宮頚部腺癌 / acrobeads test / fertilizing capacity / 男性不妊 / 細胞融合 / 精子 / アクロビーズテスト / 受精能 / Gel mobility shift assay / NF-kappaB / nuclear factor / Choriocarcimoma / Major histocompatibility / 転写因子 / 免疫学的妊娠維持機溝 / trophoblast / ゲル移動度シフト法 / NF-kB / 核蛋白 / 絨毛癌細胞株 / 主要組織適合抗原 / Uterine leiomyoma / Gynecologic cancer / PGK gene / Clonality / 子宮筋腫 / PGK遺伝子 / クロナリティ / beta2-glycoprotein I / カルジオリピン抗体 / 抗体遺伝子 / ループスアンチコアグラント / β2-glycoprotein / Antiphospholipid antibody / β2-glycoprotein I / Anti-cardiolipin antibody / Activated partial thromboplastin time / オキシトシン・レセプター / フィブロネクチン / hCG / IL‐6 / アポトーシス / 胎盤絨毛 / transcriptional regulation / gene / monoclonal antibodies / transient expression / oxytocin / 抗ヒトオキシトシン抗体 / in situ hybridization / 5′上流領域 / オキシトシン受容体遺伝子 / 一過性発現系 / 転写調節領域 / 遺伝子 / 一過性発現 / オキシトシン / gene mutation / anti-oncogenes / oncogenes / chrion / choriocarcinoma / hydatidiform mole / 遺伝子変異 / 癌抑制遺伝子 / 癌遺伝子 / 絨毛 / 胞状奇胎 / ovarian cancer / zymography / endometrial carcinoma / gelatinase / typeIV collagenase / tumor invasion / 92KDa4型コラゲナーゼ / 220KDa4型コラゲナーゼ / 92KDaIV型コラゲナーゼ / 220KDaIV型コラゲナーゼ / ザイモグラフィー / 卵巣癌 / ザイモグラフィ / ジェラチナーゼ / タイプNコラゲナーゼ / 腫瘍浸潤 / 臍帯動静脈血 / 羊水 / 新生児 / 胎児 / 中枢神経機能評価法 / プロスタグランジンD合成酵素 Less
  • Research Projects

    (24 results)
  • Co-Researchers

    (22 People)
  •  着床期子宮内膜に対する遺伝子導入法の確立と着床不全モデルの確立Principal Investigator

    • Principal Investigator
      東 千尋
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The elucidation of the mechanism of abortion/ premature birth by the key enzymes (PLA2 and COX) in the arachidonic acid cascade

    • Principal Investigator
      KOYAMA Masayasu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of function of protease inhibitor in the human reproduction area and its clinical application

    • Principal Investigator
      SHIMOYA Koichiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  プロスタグランジンD合成酵素による胎児及び新生児の中枢神経機能評価法

    • Principal Investigator
      信永 敏克
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Transcriptional regulation of oxytocin receptor and mechanism of preterm labor

    • Principal Investigator
      TAKEMURA Masahiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of pathophysiology of fetal central nerve injury and development for the method of evaluation

    • Principal Investigator
      KIMURA Tadashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The effect of prostaglandin D synthetase (PGDS) on fertilization, ovum transport and implantation.

    • Principal Investigator
      TOKUGAWA Yosihiro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of the genetic background of preterm labor using oxytocin receptor gene.

    • Principal Investigator
      KANZAKI Toru, 佐治 文隆
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Comparison of pathogenesis between human uterine cervical dysplasia and carcinoma in situPrincipal Investigator

    • Principal Investigator
      AZUMA Chihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of molecules for fertilization on human spermatozoa and oocytes

    • Principal Investigator
      OHASHI Kazutomo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The analysis of genomic imprinting in ovarian teratomas and choriocarcinoma

    • Principal Investigator
      SIMOYA Kouichirou
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of the oxytocin unresponsiveness due to the mutant oxytocin receptor.

    • Principal Investigator
      TOKUGAWA Yoshihiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Analysis of labor onset by construction of oxytocin receptor deficient micePrincipal Investigator

    • Principal Investigator
      AZUMA Chihiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Molecular analysis of fertilizing ability in human spermatozoa

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Bystander killing effect in gynecological cancer.

    • Principal Investigator
      SAMEJIMA Yoshihiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Moleccular analysis of human leukocyto antigens in trophblast derived cells

    • Principal Investigator
      KOYAMA Masayasu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Molecular analysis of human parturition using oxytocin receptor

    • Principal Investigator
      KIMURA Tadashi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Studies of human trophoblast derived factors which regulate fetal and placental development

    • Principal Investigator
      SAJI Fumitaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  HETEROGENEITY AND DIVERSITY OF IgMAND IgGLUPUS ANTICOAGULANTS

    • Principal Investigator
      KAMIURA Shoji
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Research on the clonal analysis of gynecologic tumors

    • Principal Investigator
      SAWADA Masumi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  The study to the role of extra-cellular marorix in the metastasis and invesion of malignat tumor of gynecological field

    • Principal Investigator
      TANIZAWA Osamu, 谷澤 修
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Interactions between cel cycle regulatory genes and anti-oncogenes contributed to the malignant potential of hydatidiform mole

    • Principal Investigator
      OHASHI Kazutomo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University
  •  Studies on the Pathogenesis of Trophoblastic Tumors by DNA Fingerprint and its Relationship With Growth FactorPrincipal Investigator

    • Principal Investigator
      KOYAMA Masayasu, 東 千尋
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Osaka University Medical School
  •  Identification of the region in the hCG cDNA associating its bioactivity by using biotechnology

    • Principal Investigator
      TANIZAWA Osamu
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      OSAKA UNIVERSITY
  • 1.  OHASHI Kazutomo (30203897)
    # of Collaborated Projects: 15 results
    # of Collaborated Products: 0 results
  • 2.  SAJI Fumitaka (90093418)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 3.  KOYAMA Masayasu (00183351)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 4.  SIMOYA Kouichirou (40291950)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  KAMIURA Syouji (10243213)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 6.  TOKUGAWA Yoshihiro (70283786)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  KIMURA Tadashi (90240845)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 8.  TAKEMURA Masahiko (50294062)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 9.  HASHIMOTO Kazumasa (80301266)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 10.  ISAKA Shigeyuki (50346201)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  信永 敏克 (40273677)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  TANIZAWA Osamu (30028443)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MATSUZAKI Noboru (30199781)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  MITSUDA Nobuaki (50209805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  SAMEJIMA Yoshihiro (30231351)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  KANZAKI Toru (00263278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  MURATA Yuji (40283759)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  SAWADA Masumi (60226074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  OTA Yukinobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  志岐 保彦
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  細野 剛良
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  久保田 康愛
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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