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HIROSHI Nakanishi  中西 博

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… Alternative Names

NAKANISHI Hiroshi  中西 博

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Researcher Number 20155774
Other IDs
External Links
Affiliation (Current) 2025: 安田女子大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 安田女子大学, 薬学部, 教授
2016 – 2017: 九州大学, 歯学研究院, 教授
2012 – 2015: 九州大学, 歯学研究科(研究院), 教授
2014: 九州大学, 歯学研究院, 教授
2012: 九州大学, 歯学研究院, 教授 … More
2010: 九州大学, 歯学研究院, 教授
2007 – 2010: Kyushu University, Faculty of Dental Sciences, Professor
2008: 九州大学, 大学院歯学研究院, 教授
2006: 九州大学, 歯学研究科, 教授
2005 – 2006: 九州大学, 歯学研究院, 教授
2002 – 2004: 九州大学, 大学院・歯学研究院, 教授
2000: KYUSHU UNIVERSITY, GRADUATE SCHOOL OF DENTAL SCIENCE, PROFESSOR, 大学院・歯学研究院, 教授
1999: 九州大学, 歯学部, 助教授
1990 – 1998: 九州大学, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Functional basic dentistry / Basic Section 46010:Neuroscience-general-related / Medium-sized Section 57:Oral science and related fields / Biological Sciences / Biological Sciences
Except Principal Investigator
Functional basic dentistry / Functional basic dentistry / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Periodontology … More / Pain science / Psychiatric science / Conservative dentistry / Pathobiological dentistry/Dental radiology / Biological Sciences Less
Keywords
Principal Investigator
ミクログリア / カテプシンE / カテプシンD / microglia / カテプシンS / 生体イメージング / ジンジバリス菌 / cathepsin D / ovalbumin / 老化 … More / IFN-γ / 神経障害性疼痛 / カテプシンB / NMDA受容体 / パッチクランプ / 培養上清 / 初代培養ミクログリア / 酵素活性 / IFN-beta / グリオーシス制御 / インターフェロン-beta / アストロサイト / インターフェロン-beta / トル様受容体3 / インターフェロンーbeta / Toll様受容体3 / カテプシンH / グリオーシス / 脳炎症 / 時計遺伝 / 網羅的遺伝子解析 / アルツハイマー病 / 炎症性反応 / 時計遺伝子 / 社会行動障害 / シナプス活動 / 概日リズム / シナプス強度 / スパイン密度 / 社会的行動 / 疼痛炎症 / 炎症疼痛 / M1/M2極性転換 / 分子スイッチ / プロテアーゼ反応 / カテプシン / P2Y6受容体 / 突起伸展 / 生体蛍光イメージング / lysosomal storage / nitric oxide / senescence / 未梢血管内注入 / GFPトランスジェニックマウス / 活性酸素種 / 単核貧食細胞 / 酵素補充 / リソソーム蓄積 / 単核貪食細胞 / conditioned medium / electrophysiology / NMDA receptor / macrophage / 電気生理 / マクロファージ / cathepsin D-deficient mice / invaliant chain / antigenic peptide / antigen presentation / cathepsin E / インターフェロン-γ / インターロイキン-2 / pepstatin A / カテプシン阻害剤 / カテプシンD欠損マウス / インバリアント鎖 / 抗原ペプチド / 抗原提示 / カテプシンンD / APOPTOSIS / BCL-2 / CASPASE-3 / PC12 CELL / PEPSTATIN A / LIPOPOLYSACCHARIDE / INTERFERON-gamma / MICROGLIA / CATHEPSIN E / ルミノール反応 / イムノブロット / ネクローシス / INF-γ / アポトーシス / Bcl-2 / PC12細胞 / カスパーゼ3 / ペプスタチンA / LPS / PHAGOCYTOSIS / LYSOSOME / AGING / TRIGEMINAL GANGLION / CATHEPSINS / ラット / 免疫電顕 / 免疫組織 / カテプシン群 / リソソーム系蛋白分解機構 / 三叉神経節神経細胞 / IFN- γ / Unc93b / TOLL様受容体と慢性疼痛 / Toll様受容体 / 歯科薬理学 / IL-18 / NF-κB / カスパーゼ-1 / IL-1β / T細胞 / オートファジー / モルヒネ / 慢性疼痛 / 炎症性疼痛 / クロモグラニンA / CD44 / ICAM-1 / RANKL / TGF-β1 / プロスタグランジンE2 / アジュバント関節炎 / リン質リポソーム / アルカリフォスファターゼ / 炎症生骨吸収 / ホスファチジルセリン / 破骨細胞 / 骨芽細胞 / 炎症性骨吸収 / リポソーム / 顔面神経 / 神経科学 / 軸索再生 / テネシンR / 軸索切断 / 顔面神経運動ニューロン / 長期増強 / パッチクランプ法 / グリシン / HPLC / グリシン結合部位 / 海馬CA1野ニューロン / 脳虚血 / GluR / リアルタイムRT-PCR / 細胞周期 / カイニン酸受容体 / dendritic beading / ATP / synaptic stripping / 神経伝達 / グルタミン酸 / 糖鎖 / エンドソーム / プロセッシング / 生合成 / DNA損傷 / 逆行性変性 / 顔面神経核 / 免疫組織化学 / 咬筋運動ニューロン / 分解調節 / basic FGF / アスパラギン酸プロテアーゼ … More
Except Principal Investigator
ミクログリア / Porphyromonas gingivalis / Arg-gingipain / カテプシンE / Lys-gingipain / 歯周病 / プロセシング / cytokine / カテプシン / 髄膜 / システインプロテアーゼ / 生合成 / 細胞内アスパラギン酸プロテアーゼ / グリア細胞 / 歯周病原性プロテアーゼ / アスパラギン酸プロテアーゼ / 胸腺細胞 / カテプシンD / free radical / Alzheimer / ISH / osteoclast / osteoprotegerin / RANK / RANKL / microglia / Bcl-2 / periodontal disease / 病原性プロテアーゼ / 歯周病原菌 / cysteine proteinases / 歯周病原性菌 / 歯肉溝滲出液 / 臨床評価法 / 歯周疾患 / 三叉神経節 / 炎症 / 三叉神経脊髄路核 / アルツハイマー病 / 老化 / 髄膜細胞 / アジュバント関節炎 / サイトカイン / 脳炎症 / 末梢炎症 / グラム陰性嫌気性細菌 / CHO細胞 / フレンド細胞 / 細胞内輸送 / 新規標的蛋白質 / 持続感染 / アクセサリー蛋白質 / ヘニパウイルス / 異常疼痛 / 口腔乾燥症 / 口腔生理学 / 歯学 / TRPV1 / 痛覚過敏 / 三叉神経節細胞 / 舌機械痛覚過敏 / トリップチャネルV4 / p38マップキナーゼ / 衛星細胞 / TRPV4 / p38 / 舌乾燥 / 舌痛 / 口腔乾燥 / 疫学調査 / 口腔健康 / アルツハイマー型認知症 / 全身炎症 / 認知機能 / 歯肉増殖 / 歯肉増殖症 / NMDA receotors / patch clamp / glial cells / inflammatory cytokines / leptomeninges / pain / アストロサイト / 下歯槽神経切断 / パッチクランプ / NMDA受容体 / パッチリランプ / 炎症性サイトカイン / 三叉神経痛 / beta amyloid / inflammation / microglio / bota-amilaid / フリーラジカル / βアミロイド / 破骨細胞 / 蛍光抗体法 / M-CSF / 歯根膜 / rat / periodontal tissue / caspase / PC12 cells / aging / neuronal death / intracellular aspartic proteinase / cathepsin E / 分化誘導 / 遺伝子導入 / 神経細胞 / 細胞死モデル / PC19細胞 / カスパーゼ / PC12細胞 / 神経細胞死 / novel inhibitors / porphyromonas gingivalis / gram-negative anaerobic bacterium / pathogen / periodontitis / 歯周病ワクチン / プロテアーゼインヒビター / 歯周病治療薬 / インヒビター / Agr-gingipain / 歯周菌 / 放線菌 / 新規阻害物質 / ジンジバリス菌 / 病原性細菌 / crysteine proteinase / virulence factors / oral anaerobic bacterium / 病原菌プロテアーゼ / 病原性発現機序 / 病原性因子 / Porphyromonase gingivalis / cathepsins / oral bacterium / proteinases / drug design / clinical parameter / 臨床評価法の確立 / 治療薬の開発 / primary structures / cloning / a virulence factor / periodontal pathogen / 機能と病態 / 蛋白質一次構造 / 遺伝子のクローニング / 病原性システインプロテアーゼ / Argingipain / 病原因子 / GINGIVAL CREVICULAR FLUID / MEDULLASIN / CATHEPSIN G / CATHEPSIN L / CATHEPSIN H / CATHEPSIN B / GINGIVITIS / PERIODONTITIS / プロテア-ゼ / カテプシンG / 顆粒球セリンプロテア-ゼ / 歯周組織の破壊 / 歯周組織破壊 / タンパク分解酵素 / P2Y12 / ATP / 舌神経 / ニューロン-グリア機能連関 / 延髄 / 神経損傷 / アストログリア / 異所性痛覚過敏 / 神経障害性疼痛 / 疼痛制御 / 三叉神経 / 神経科学 / 歯科基礎医学 / パラインフラメーション / TLR2 / pgLPS / IL-1 b / 歯周病菌LPS / PGE_2〓 / 密着結合蛋白質 / PGE_2 / 未着結合蛋白質 / PGE / カテプシンB / IL-1β / LPS / 密着結合タンパク質 / 髄膜-グリア / 病者行動 / バッテン病 / 神経系 / 品質管理 / エンドソーム・リソソーム系 / 神経変性疾患 / 蛋白質分解酵素 / エンドソーム・リソソーム / オートオファジー / 蛋白質分解 / タンパク質分解 / 生体防御 / オートファジー / ノックアウトマウス / リソソーム系 / エンドソーム / マクロファージ / ノックアウト / Prophyromonas gingivalis / 酵素欠損変異体 / 蛋白分解システム / 選別輸送機構 / チャイニーズハムスター卵巣細胞 / マウス白血病フレンド細胞 / 活性化機構 / カプテシンD Less
  • Research Projects

    (42 results)
  • Research Products

    (467 results)
  • Co-Researchers

    (38 People)
  •  シダーウイルスをモデルとしたヘニパウイルス脳炎再発機序の解明と治療戦略への応用

    • Principal Investigator
      小田 康祐
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Yasuda Women's University
  •  Regulatory mechanisms of the gliosis through TLR3/IFN-b signaling mediated by microgliaPrincipal Investigator

    • Principal Investigator
      Nakanishi Hiroshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      Yasuda Women's University
  •  Possible involvement of impaired intrinsic microglial clock in Periodontotis-associated exacerbation of Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      Nakanishi Hiroshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Yasuda Women's University
  •  Comprehensive understanding of orofacial pain induced by dry mouth

    • Principal Investigator
      IWATA Koichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nihon University
  •  ミクログリアのナイトライフの解析から捉える概日リズム障害発症メカニズムPrincipal Investigator

    • Principal Investigator
      中西 博
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Japan-China Joint Epidemiological Survey of Tibetan Elderly on Correlation between Oral Health and Cognitive Functions

    • Principal Investigator
      Take Hiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  the unravelling of the role of cathepsin in gingival overgrowth

    • Principal Investigator
      Yamashita Akiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Kyushu University
  •  Analysis of Porphyromonas gingivalis-induced neuroinflammation by multi-photon imaging of microglia dynamicsPrincipal Investigator

    • Principal Investigator
      Nakanishi Hiroshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Study on a microglial phenotypic switch with a focus on proteolytic responsePrincipal Investigator

    • Principal Investigator
      Nakanishi Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain statePrincipal Investigator

    • Principal Investigator
      HIROSHI Nakanishi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Mechanism of the rupture of meningeal-glia limitans during chronic Periodontitis

    • Principal Investigator
      TAKE Hiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Involvement of endosomal Toll-like receptors in the development of neuropathic painPrincipal Investigator

    • Principal Investigator
      HIROSHI Nakanishi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Involvement of glia-neuron functional interaction in intractable trigeminal neuropathic pain

    • Principal Investigator
      IWATA Koichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nihon University
  •  Inhibition of bone destruction by phosphatidylserine-containing liposomes based on t he regulation of phagocytes functionsPrincipal Investigator

    • Principal Investigator
      HIROSHI Nakanishi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Roles of cathepsin B in the production of IL-1β as a leptomenigal toxic factor during systemic inflammation

    • Principal Investigator
      TAKE Hiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Age-dependent differential responses of glial cells and Leptomeningeas during systemic inflammation

    • Principal Investigator
      SHINDOU Mayumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Okinawa Institute of Science and Technology
  •  Association of leptomeningeal and glial cells in the persistent pain

    • Principal Investigator
      TAKE Hiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pain science
    • Research Institution
      Kyushu University
  •  顔面神経-ミクログリアの細胞膜間に想定される軸索再生分子の探索Principal Investigator

    • Principal Investigator
      中西 博
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Research on the mechanism underlying the accelerated senescence in cathepsin D-deficient micePrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  ミクログリアによるグルタミン酸を介した神経伝達の動的制御Principal Investigator

    • Principal Investigator
      中西 博
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  The study on microglial activation by beta amyloid, peptides of Alzheimer's disease.

    • Principal Investigator
      MONJI Akira
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      KYUSHU UNIVERSITY
  •  Regulation of glutamatergic signalings by niacrophage/microgliaPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  In situ expression of RANKL, RANK, osteoprotegerin and cytokines in osteoclasts of rat periodontal tissue

    • Principal Investigator
      YOSHIMINE Yoshito
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kyushu University
  •  神経系におけるオートファジー・リソソームシステム

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  Involvement of cathepsin E in exogenous antigen processing in primary cultured microgliaPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  エンドソーム・リソソーム系蛋白分解機構におけるカテプシンEの役割

    • Principal Investigator
      山本 建二
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  カテプシンEの生合成と細胞内輸送および局在化機構の解析

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  歯周病原菌における蛋白分解システムとその異常の分子レベル解析

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  DESIGN AND DEVELOPMENT OF THERAPEUTIC AGENTS OF ADULT PERIODONTITIS THAT INHIBIT ARG-GINGIPAIN PRODUCED BY PORPHYROMONAS GINGIVALIS

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  Effect of overexpression of cathepsin E and Bcl-2 on neuronal death

    • Principal Investigator
      HORI Nobuaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  EXPRESSION AND FUNCTION OF CATHEPSIN E IN ACTIVATED MICROGLIA FOLLOWING FACIAL NERVE INJURYPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  細胞内アスパラギン酸プロテアーゼの機能構造形成と細胞機能制御

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  顔面神経切断に伴って増殖する反応性ミクログリアにおけるカテプシンEの性状解析Principal Investigator

    • Principal Investigator
      中西 博
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  ROLES OF PATHOGENIC PROTEINASES IN PERIODONTAL DISEASE

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  DNA断片化ならびに細胞内プロテアーゼの動態を指標として逆行性神経変性の検討Principal Investigator

    • Principal Investigator
      中西 博
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  細胞内アスパラギン酸プロテアーゼの選別と輸送機構

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  アスパラギン酸プロテアーゼによる生理活性ペプチドの分解を介した三叉神経機能の調節Principal Investigator

    • Principal Investigator
      中西 博
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  Structures and Functions of Periodontopathogenic Proteinases

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyushu University
  •  DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR ASSESSMENT OF PROGRESSIVE PERIODONTAL DIDEASE AND ITS THERAPEUTIC AND PREVENTIVE DRUGS

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUShU UNIVERSITY
  •  PHYSIOLOGICAL AND PATHOLOGICAL STUDIES OF PROTEINASES IN THE RAT TRIGEMINAL GANGLION CELLSPrincipal Investigator

    • Principal Investigator
      NAKANISHI Hiroshi Ph.D.
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  THE DEVELOPMENT OF A NEW CLINICAL PARAMETER FOR DIAGNOSIS OF PERIODONTAL DISEASES AND THE NEW DRUG DESIGN

    • Principal Investigator
      YAMAMOTO Kenji
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      KYUSHU UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 口腔疾患と時間栄養学、「時間栄養学、;時計遺伝子、体内時計、食生活をつなぐ」2020

    • Author(s)
      中西 博
    • Total Pages
      244
    • Publisher
      化学同人
    • ISBN
      9784759820362
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Book] 脳の半分を占める グリア細胞:歯周病菌とミクログリアの不都合な関係 -アルツハイマー病治療のパラダイムシフト-2019

    • Author(s)
      中西 博、野中さおり
    • Publisher
      実験医学増刊号
    • ISBN
      9784758103824
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Book] Microglia in Health and Disease2014

    • Author(s)
      Rommy von Bernardi, Betsi Flores, Hiroshi Nakanishi
    • Total Pages
      5
    • Publisher
      Springer Science+Business Media New York
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Book] TNF-α signaling and cathepsin B, In: Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease2013

    • Author(s)
      Zhou Wu, Hiroshi Nakanishi
    • Total Pages
      15
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Book] BK+ channels contribute to the cellular activation of microglia : a big channel in small glia, In: Glial Cells: Embryonic Development, Types/Functions and Role in Disease2013

    • Author(s)
      Yoshinori Hayashi, Hiroshi Nakanishi
    • Total Pages
      18
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Book] Microglia-aging and pain: Microglial cathepsin B-dependent IL-1β production, In: Interleukin-1: Genetics, Inflammatory Mechanisms and Role in Disease2013

    • Author(s)
      Hiroshi Nakanishi, Zhou Wu
    • Total Pages
      12
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Book] TNF-α signaling and cathepsin B, In : Tumor Necrosis Factor : Structure, Enzyme Regulation and Role in Health and Disease2013

    • Author(s)
      Zhou Wu, Hiroshi Nakanishi
    • Total Pages
      15
    • Publisher
      Nova Science Publishers, Inc. New York
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Book] NMDAレセプターとミクログリア:ミクログリアのシナプス可塑性ならびにシナプス再編への関与2013

    • Author(s)
      林 良憲、中西 博
    • Total Pages
      26
    • Publisher
      日本神経精神薬理学雑誌
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Book] Involvement of microglial cathepsin B in pro-interleukin-1β processing and persistent pain. In : inflammation, Chronic Disease and Cancer-Cell and Molecular Biology, Immunology and Clinic Base2013

    • Author(s)
      Hiroshi Nakanishi, Zhou Wu
    • Total Pages
      17
    • Publisher
      Nova Science Publishers. Inc. New York
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Book] Interleukin-1: Genetics, Inflammatory Mechanisms and Role in Disease2013

    • Author(s)
      Hiroshi Nakanishi and Zhou Wu
    • Publisher
      Nova Science Publishers, Inc. New York
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Book] BK^+ channels contribute to the cellular activation of microglia : a big channel in small glia, In : Glial Cells : Embryonic Development, Types/Functions and Role in Disease2013

    • Author(s)
      Hiroshi Nakanishi, Zhou Wu
    • Total Pages
      12
    • Publisher
      Nova Science Publishers, Inc., New Yor
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Book] Tumor Necrosis Factor: Structure, Enzyme Regulation and Role in Health and Disease2012

    • Author(s)
      Zhou Wu, Hiroshi Nakanishi
    • Publisher
      Nova Science Publishers, Inc. New York
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Book] Regulation of myeloid phagocytes by phosphatidylserine-containing liposomes : possible incolvement of prostaglandin E_2 and the potential terapeutic application.(Ed., GM Goodwin)(In : Prostaglandins : Biochemistry, Functions, Types and Roles)2010

    • Author(s)
      Wu Z, Nakanishi H.
    • Publisher
      Nova Science Publisher Inc., New York
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Book] Regulation of myeloid phagocytes by phosphatidylserine-containing liposomes : possible involvement of prostagrandin E_2 and the potential terapeutic application(Ed., G.M.Goodwin)(In : Prostaglandins : Biochemistry, Functions, Types and Roles)2010

    • Author(s)
      Wu Z, Nakanishi H
    • Publisher
      Nova Science Publisher, Inc., New York
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Book] Regulation of myeloid phagocytes by phosphatidylserine-containing liposomes : possible incolvement of prostaglandin E_2 and the potential terapeutic application. (Ed., GM Goodwin)(In : Prostaglandins : Biochemistry, Functions, Types and Roles)2010

    • Author(s)
      Wu Z, Nakanishi H.
    • Publisher
      Nova Science Publisher Inc., New York
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Book] Regulation of myeloid phagocytes by phosphatidylserine- containing liposomes : possible involvement of prostagrandin E_2 and the potential terapeutic application. In : Prostaglandins : Biochemistry, Functions, Types and Roles (Ed., G.M.Goodwin)2010

    • Author(s)
      Wu Z, Nakanishi H
    • Publisher
      Nova Science Publisher, Inc., New York
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Book] In Neuroimmunology Research Focus2007

    • Author(s)
      Wu Z. and Nakanishi H.
    • Publisher
      Nova Science Publishers Inc
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Book] Age-dependent differential activation profiles of glial cells by the leptomeninges during systemic inflammationNeuroimmunology Research Focus,(Broglio PV ed)2007

    • Author(s)
      Wu Z. and Nakanishi H. (分担)
    • Publisher
      Nova Science Publishers Inc.
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Book] Microglial Proteases:In Neural Protein Metabolism and Function.Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(LajthaA ed)2007

    • Author(s)
      Nakanishi H.(分担)
    • Publisher
      Kluwer Publishing Corporation
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Book] Handbook of Neurochemistry and Molecular Neurobiology2007

    • Author(s)
      Nakanishi H.
    • Publisher
      Kluwer Publishing Corporation
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Book] Microglial Proteases:In Neural Protein Metabolism & Function.Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(Lajtha A ed)2007

    • Author(s)
      Nakanishi H.(分担)
    • Publisher
      Kluwer Publishing Corporation
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Book] Microglial Proteases: In Neural Protein Metabolism and Function. Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(Lajtha A ed)2007

    • Author(s)
      Nakanishi H. (分担)
    • Publisher
      Kluwer Publishing Corporation
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Book] Microglial Proteases: Ineural Protein Metabolism and Function. Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(LajthaA ed)2007

    • Author(s)
      Nakanishi, H.(分担)
    • Publisher
      Kluwer Publishing Corporation
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Book] Microglial Proteases:In Neural Protein Metabolism and Function.Handbook of Neurochemistry and Molecular Neurobiology, Vol.7(Lajtha A ed)2007

    • Author(s)
      Nakanishi H.(分担)
    • Publisher
      Kluwer Publishing Corporation
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Book] Microglial Proteases: In Neural Protein Metabolism & Function. Handbookof Neurochemistry and Molecular Neurobiology, vol.7 (Lajtha A ed)2007

    • Author(s)
      Nakanishi H.(分担)
    • Publisher
      Kluwer Publishing Corporation
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Book] Age-dependent differential activation profiles of glial cells by the leptomeninges during systemic inflammation: In Neuroimmmunology Research Focus,(Broglio PV ed)2007

    • Author(s)
      Wu, Z・Nakanishi, H.(分担)
    • Publisher
      Nova Science Publishers Inc.
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Book] Age-dependent differential activation profiles of glial cells by theleptomeninges during systemic inflammation: In NeuroimmunologyResearch Focus, (Broglio PV ed)2007

    • Author(s)
      Wu Z. and Nakanishi H.(分担)
    • Publisher
      Nova Science Publishers Inc
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Book] Age-dependent differential activation profiles of glial cells by theleptomeninges during systemic inflammation:In NeuroimmunologyResearch Focus, (Broglio PV ed)2007

    • Author(s)
      Wu Z., Nakanishi H.(分担)
    • Publisher
      Nova Science Publishers Inc
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Book] Age-dependent differential activation profiles of glial cells by the leptomeninges during systemic inflammation:In Neuroimmunology Research Focus, (Broglio PV ed)2007

    • Author(s)
      Wu Z.and Nakanishi H.(分担)
    • Publisher
      Nova Science Publishers Inc.
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Book] Proteases in the Brain(Proteases and synaptic activity)2005

    • Author(s)
      Nakanishi, H.
    • Publisher
      Kluwer Academic/Plenum Publisher
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Book] Protease in Biology and Disease, Chapter 12. Protease and Synaptic Activity pp. 303-〜3222005

    • Author(s)
      Nakanishi, H.
    • Total Pages
      383
    • Publisher
      Kluwer Academic/Plenum Publisher
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Book] Proteases in the Brain (Proteases and synaptic activity)2005

    • Author(s)
      Nakanishi, H.
    • Total Pages
      383
    • Publisher
      Kluwer Academic/Plenum Publisher
    • Data Source
      KAKENHI-PROJECT-17659587
  • [Book] Proteases in the Brain(Proteases and synaptic activity)2005

    • Author(s)
      Nakanishi, H.
    • Total Pages
      383
    • Publisher
      Kluwer Academic/Plenum Publisher
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Book] Kluwer Academic/Plenum Publishers2005

    • Author(s)
      Nakanishi H.(分担)
    • Publisher
      Proteases and synaptic activity.In:Proteases in Biology and Disease.Vol.3, (Eds:Lendeckel, U.and Hooper, N.)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Book] Cathepsin-dependent neuronal death pathways induced by methylmercury. (Ed. AP Clampet)(In : Methylmercury : Formation, Sources and Health Effects)

    • Author(s)
      Nakanishi H, Wu Z.
    • Publisher
      Nova Science Publisher Inc., New York (in press)
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Book] Cathepsin-dependent neuronal death pathways induced by methylmercury.(Ed. AP Clampet)(In : Methylmercury : Formation, Sources and Health Effects)

    • Author(s)
      Nakanishi H, Wu Z.
    • Publisher
      Nova Science Publisher Inc., New York, in press
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Gingipain-carrying outer membrane vesicles from Porphyromonas gingivalis cause barrier dysfunction of Caco-2?cells by releasing gingipain into the cytosol2024

    • Author(s)
      Nonaka Saori、Okamoto Rin、Katsuta Yui、Kanetsuki Shiori、Nakanishi Hiroshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 707 Pages: 149783-149783

    • DOI

      10.1016/j.bbrc.2024.149783

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Journal Article] Human β-Defensin 3 Inhibition of P. gingivalis LPS-Induced IL-1β Production by BV-2 Microglia through Suppression of Cathepsins B and L2024

    • Author(s)
      Inoue E, Minatozaki S, Shimizu S, Miyamoto S, Jo M, Ni J, Tozaki-Saitoh H, Oda K, Nonaka S, Nakanishi H
    • Journal Title

      Cells

      Volume: 13 Issue: 3 Pages: 283-283

    • DOI

      10.3390/cells13030283

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07353, KAKENHI-PROJECT-21K06383
  • [Journal Article] Zinc finger protein 335 mediates lipopolysaccharide‐induced neurodegeneration and memory loss as a transcriptional factor in microglia2023

    • Author(s)
      Kong Wei、Xie Zhen、Shang Xiaokang、Hayashi Yoshinori、Lan Fei、Narengaowa、Zhao Shuxuan、Li Hui、Quan Zhenzhen、Wu Zhou、Nakanishi Hiroshi、Qing Hong、Ni Junjun
    • Journal Title

      Glia

      Volume: 71 Issue: 12 Pages: 2720-2734

    • DOI

      10.1002/glia.24447

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09927, KAKENHI-PROJECT-21K06383
  • [Journal Article] Targeting cellular gaps using Janus nanoparticles containing cationic polymers and surfactant lipids2023

    • Author(s)
      Akihiro Matsumoto, Takeo Kitazawa, Yuta Hatori, Masahiro Murakami, Hiroshi Nakanishi, Chie Watanabe, Tomoya Takashima, Masahiro Murakami
    • Journal Title

      Drug Discoveries & Therapeutics

      Volume: 17 Issue: 2 Pages: 104-113

    • DOI

      10.5582/ddt.2022.01118

    • ISSN
      1881-7831, 1881-784X
    • Year and Date
      2023-04-30
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K12828, KAKENHI-PROJECT-21K06090, KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-21K07224
  • [Journal Article] Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease2022

    • Author(s)
      Xie Zhen、Meng Jie、Kong Wei、Wu Zhou、Lan Fei、Narengaowa、Hayashi Yoshinori、Yang Qinghu、Bai Zhantao、Nakanishi Hiroshi、Qing Hong、Ni Junjun
    • Journal Title

      Aging Cell

      Volume: 21 Issue: 3

    • DOI

      10.1111/acel.13565

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-20K09896
  • [Journal Article] Secreted gingipains from Porphyromonas gingivalis induce increased permeability of human cerebral microvascular endotherial cells through intracellular degradation of tight junction proteins.2022

    • Author(s)
      Nonaka S, Kadowaki T, Nakanishi H.
    • Journal Title

      Neurochemistry International

      Volume: 154 Pages: 105282-105282

    • DOI

      10.1016/j.neuint.2022.105282

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-22K15287
  • [Journal Article] ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway2022

    • Author(s)
      Hatori Yuta、Kanda Yukina、Nonaka Saori、Nakanishi Hiroshi、Kitazawa Takeo
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 11 Pages: e0276823-e0276823

    • DOI

      10.1371/journal.pone.0276823

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06090, KAKENHI-PROJECT-21K06383
  • [Journal Article] Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease.2022

    • Author(s)
      Xie Z , Meng J, Kong W, Wu Z, Lan F, Narengaowa, Hayashi Y, Qinghu Yang Q, Bai Z, Nakanishi H, Qing H, Ni J.
    • Journal Title

      Aging Cell

      Volume: 21

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Journal Article] Human β-Defensin 3 Inhibits Porphyromonas Gingivalis Lipopolysaccharide-Induced Oxidative and Inflammatory Responses of Microglia by Suppression of Cathepsins B and L2022

    • Author(s)
      Inoue Erika、Minatozaki Shiyo、Katsuta Yui、Nonaka Saori、Nakanishi Hiroshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 23 Pages: 15099-15099

    • DOI

      10.3390/ijms232315099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Journal Article] Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response2021

    • Author(s)
      Nakanishi Hiroshi、Ni Junjun、Nonaka Saori、Hayashi Yoshinori
    • Journal Title

      Neurochemistry International

      Volume: 142 Pages: 104905-104905

    • DOI

      10.1016/j.neuint.2020.104905

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K19650
  • [Journal Article] Generation of CSF-1 independent ramified microglia from leptomeninges in vitro.2021

    • Author(s)
      Tanaka J, Takahashi H, Yano H, Nakanishi H.
    • Journal Title

      Cells

      Volume: 10 Pages: 24-24

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Journal Article] Cathepsin H deficiency decreases hypoxia-ischemia-induced hippocampal atrophy in neonatal mice through attenuated TLR3/INF-β signaling.2021

    • Author(s)
      Ni J, Zhang X, Reinheckel T, Turk V, Nakanishi H.
    • Journal Title

      J. Neuroinflammation

      Volume: 18 Issue: 1 Pages: 176-176

    • DOI

      10.1186/s12974-021-02227-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Journal Article] Stem cells from human exfoliated deciduous teeth attenuate mechanical allodynia in mice through distinct from the siglec-9/MCP-1-mediated tissue-repairing mechanism2021

    • Author(s)
      Hayashi Yoshinori、Kato Hiroki、Nonaka Kazuaki、Nakanishi Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 20053-20053

    • DOI

      10.1038/s41598-021-99585-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K06383
  • [Journal Article] Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response.2021

    • Author(s)
      Nakanishi H., Ni J., Nonaka S., Hayashi Y.
    • Journal Title

      Neurochemistry International

      Volume: 142 Pages: 104905-104905

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Journal Article] Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury2021

    • Author(s)
      Liu Yicong、Li Hui、Hu Jiangqi、Wu Zhou、Meng Jie、Hayashi Yoshinori、Nakanishi Hiroshi、Qing Hong、Ni Junjun
    • Journal Title

      Molecular Neurobiology

      Volume: 59 Issue: 1 Pages: 717-730

    • DOI

      10.1007/s12035-021-02594-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K06383
  • [Journal Article] Generation of CSF1-Independent Ramified Microglia-Like Cells from Leptomeninges In Vitro2020

    • Author(s)
      Tanaka J, Takahashi H, Yano H, Nakanishi H.
    • Journal Title

      Cells

      Volume: 10 Issue: 1 Pages: 24-37

    • DOI

      10.3390/cells10010024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09333, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-20K21465
  • [Journal Article] Cathepsin regulation on microglial function.2020

    • Author(s)
      Nakanishi H.
    • Journal Title

      Biophys Biochim Acta Proteins Proteom.

      Volume: 1868 Issue: 9 Pages: 140465-140465

    • DOI

      10.1016/j.bbapap.2020.140465

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] . Involvement of cathepsins in innate and adaptive immune responses in periodontitis.2020

    • Author(s)
      Yan X, Wu Z, Wang B, Yu T, Hu Y, Wang S, Deng C, Zhao B, Nakanishi H, Zhang X.
    • Journal Title

      Evid Based Complement Alternat Med.

      Volume: 2020 Issue: 1 Pages: 4517587-4517587

    • DOI

      10.1155/2020/4517587

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Neural stem cell?specific ITPA deficiency causes neural depolarization and epilepsy2020

    • Author(s)
      Koga Yuichiro、Tsuchimoto Daisuke、Hayashi Yoshinori、Abolhassani Nona、Yoneshima Yasuto、Sakumi Kunihiko、Nakanishi Hiroshi、Toyokuni Shinya、Nakabeppu Yusaku
    • Journal Title

      JCI Insight

      Volume: 5 Issue: 22

    • DOI

      10.1172/jci.insight.140229

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K06960, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H06276
  • [Journal Article] Secreted gingipains from Porphyromonas gingivalis induce microglial migration through endosomal signaling by protease-activated receptor 2.2020

    • Author(s)
      Nonaka S, Nakanishi H.
    • Journal Title

      Neurochem. Int.

      Volume: 140 Pages: 104840-104840

    • DOI

      10.1016/j.neuint.2020.104840

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Microglial cathepsin B and Porphyromonas gingivalis gingipains as potential therapeutic targets for sporadic Alzheimer’s disease.2020

    • Author(s)
      Nakanishi H., Nonaka S., Wu Z.
    • Journal Title

      CNS & Neurol Disod. Drug Targets

      Volume: 19 Issue: 7 Pages: 495-502

    • DOI

      10.2174/1871527319666200708125130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging.2020

    • Author(s)
      Nakanishi H.
    • Journal Title

      Neural Regener Res

      Volume: 15 Issue: 1 Pages: 25-29

    • DOI

      10.4103/1673-5374.264444

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Induction of bone repair in rat calvarial defects using a combination of hydroxyapatite with phosphatidylserine liposomes2019

    • Author(s)
      Hatakeyama J, Anan H, Hatakeyama Y, Matsumoto N, Takayama F, Wu Z, Matsuzaki E, Minakami M, Izumi T, Nakanishi H
    • Journal Title

      Journal of Oral Science

      Volume: 61 Issue: 1 Pages: 111-118

    • DOI

      10.2334/josnusd.17-0488

    • NAID

      130007626633

    • ISSN
      1343-4934, 1880-4926
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11032, KAKENHI-PROJECT-17K11728, KAKENHI-PROJECT-18K19650
  • [Journal Article] Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis.2019

    • Author(s)
      Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, Yamamoto K, Kira JI, Nakanishi H, Hayashi Y.
    • Journal Title

      Pain

      Volume: 160 Issue: 9 Pages: 2050-2062

    • DOI

      10.1097/j.pain.0000000000001596

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16K11477
  • [Journal Article] Microglial clearance of focal apoptotic synapses.2019

    • Author(s)
      Nonaka S, Nakanishi H.
    • Journal Title

      Neurosci. Lett.

      Volume: 707 Pages: 134317-134317

    • DOI

      10.1016/j.neulet.2019.134317

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Mutations of beta-amyloid precursor protein after the consequence of Alzheimer's disease pathogenesis.2019

    • Author(s)
      Li NM, Liu KF, Qiu YJ, Zhang HH, Nakanishi H, Qing H.
    • Journal Title

      Neural Regen Res.

      Volume: 14 Issue: 4 Pages: 658-665

    • DOI

      10.4103/1673-5374.247469

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.2019

    • Author(s)
      Ni J, Wu Z, Meng J, Saito T, Saido TC, Qing H, Nakanishi H.
    • Journal Title

      J. Neuroinflamm.

      Volume: 16 Issue: 1 Pages: 173-173

    • DOI

      10.1186/s12974-019-1562-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Pterostilbene, an active component of the dragon’s blood extract, acts as an antiderpressant in adult rats.2019

    • Author(s)
      Yang L, Ran Y, Quan Z, Wang R, Yang Q, Jia Q, Zhang H, Li Y, Peng Y, Liang J, Wang H, Nakanishi H, Deng Y, Qing H.
    • Journal Title

      Psychopharmacology (Berl)

      Volume: 14 Issue: 4 Pages: 658-665

    • DOI

      10.1007/s00213-018-5138-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Manipulation of hippocampal CA3 firing via luminopsins modulates spatial and episodic short-term memory, especially working memory, but not long-term memory.2018

    • Author(s)
      Song D, Yang Q, Lang Y, Wen Z, Xie Z, Zheng D, Yan T, Deng Y, Nakanishi H, Qing H
    • Journal Title

      Neurobiol Learn Mem

      Volume: 155 Pages: 435-445

    • DOI

      10.1016/j.nlm.2018.09.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Journal Article] Brazilian green propolis prevents cognitive decline into mild cognitive impairment in elderly people living at high altitude.2018

    • Author(s)
      Zhu A, Wu Z, Zhong X, Ni J, Li Y, Meng J, Du C, Zhao X, Nakanishi H, Wu S
    • Journal Title

      J Alzheimers Dis.

      Volume: 63 Issue: 2 Pages: 551-560

    • DOI

      10.3233/jad-170630

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-17K17093
  • [Journal Article] Ratanasampil Suppresses the Hypoxia-Related Inflammatory Responses by Inhibiting Oxidative Stress and NF-kB Activation in Microglia2018

    • Author(s)
      Zhu Aiqin、Zhong Xin、Nian Wei、Wu Shizheng、Meng Jie、Ni Junjun、Hayashi Yoshinori、Wu Zhou、Nakanishi Hiroshi
    • Journal Title

      Journal of Alzheimer’s Disease & Parkinsonism

      Volume: 08 Issue: 05 Pages: 451-451

    • DOI

      10.4172/2161-0460.1000451

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11478
  • [Journal Article] Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE through impairment toll-like receptor 3 cascade.2018

    • Author(s)
      Okada R, Zhang Z, Harada Y, Wu Z, Nakanishi H
    • Journal Title

      Inflamm Res

      Volume: 67 Pages: 371-374

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Journal Article] Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.2018

    • Author(s)
      Ni J, Wu Z, Stoka V, Meng J, Hayashi Y, Peters C, Qing H, Turk V, Nakanishi H. Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice
    • Journal Title

      Aging Cell

      Volume: . Issue: 1

    • DOI

      10.1111/acel.12856

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-17K17093
  • [Journal Article] 歯周病のアルツハイマー病における関与メカニズム2018

    • Author(s)
      武 洲、中西 博
    • Journal Title

      細胞・特集・口腔疾患のサイエンス・Current Topics in Oral Science

      Volume: 50 Pages: 45-49

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Journal Article] The critical role of IL-10 in the antineuroinflammatory and antioxidant effects of Rheum tanguticum on activated microglia.2018

    • Author(s)
      Meng J, Ni J, Wu Z, Jiang M, Zhu A, Qing H, Nakanishi H.
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2018:1083596 Issue: 1 Pages: 1-12

    • DOI

      10.1155/2018/1083596

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-17K17093
  • [Journal Article] A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain.2018

    • Author(s)
      Fujii T, Yamasaki R, Iinuma K, Tsuchimoto D, Hayashi Y, Saitoh BY, Matsushita T, Kido MA, Aishima S, Nakanishi H, Nakabeppu Y, Kira JI.
    • Journal Title

      Annals of Neurology

      Volume: 84 Issue: 2 Pages: 208-224

    • DOI

      10.1002/ana.25279

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-17K19663, KAKENHI-PROJECT-17H01391
  • [Journal Article] Cathepsin H deficiency in mice induces excess Th1 cell activation and early-onset of EAE through impairment toll-like receptor 3 cascade.2018

    • Author(s)
      Okada R, Zhang Z, Harada Y, Wu Z, Nakanishi H
    • Journal Title

      Inflamm Res

      Volume: 67 Pages: 371-374

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Journal Article] Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis2017

    • Author(s)
      Dekita Masato、Wu Zhou、Ni Junjun、Zhang Xinwen、Liu Yicong、Yan Xu、Nakanishi Hiroshi、Takahashi Ichiro
    • Journal Title

      Frontiers in Pharmacology

      Volume: 8 Pages: 1-13

    • DOI

      10.3389/fphar.2017.00470

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
  • [Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice2017

    • Author(s)
      Liu Yicong、Wu Zhou、Nakanishi Yurika、Ni Junjun、Hayashi Yoshinori、Takayama Fumiko、Zhou Yanmin、Kadawaki Tomoko、Nakanishi Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41598-017-12173-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-18K19650
  • [Journal Article] Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats2017

    • Author(s)
      Zhang Xinwen、Wu Zhou、Liu Yicong、Ni Junjun、Deng Chunfu、Zhao Baohong、Nakanishi Hiroshi、He Jing、Yan Xu
    • Journal Title

      Evidence-Based Complementary and Alternative Medicine

      Volume: 2017 Issue: 1 Pages: 1-10

    • DOI

      10.1155/2017/3679295

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
  • [Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017

    • Author(s)
      Liu Y, WU Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H
    • Journal Title

      Sci Rep

      Volume: 7:11759

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Journal Article] Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin.2017

    • Author(s)
      Harada Y, Takayama F, Tanabe K, Ni J, Hayashu Y, Yamamoto K, Wu Z, Nakanishi H
    • Journal Title

      Cell Mol Neurobiol

      Volume: 37 Pages: 437-443

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Journal Article] Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice2017

    • Author(s)
      Takayama Fumiko、Zhang Xinwen、Hayashi Yoshinori、Wu Zhou、Nakanishi Hiroshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 490 Issue: 2 Pages: 447-452

    • DOI

      10.1016/j.bbrc.2017.06.061

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
  • [Journal Article] The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells2017

    • Author(s)
      Ni Junjun、Wu Zhou、Meng Jie、Zhu Aiqin、Zhong Xin、Wu Shizheng、Nakanishi Hiroshi
    • Journal Title

      Oxidative Medicine and Cellular Longevity

      Volume: 2017 Issue: 1 Pages: 1-13

    • DOI

      10.1155/2017/7984327

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
  • [Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017

    • Author(s)
      Liu Y, WU Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H
    • Journal Title

      Sci Rep

      Volume: 7:11759

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Journal Article] Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin.2017

    • Author(s)
      Harada Y, Takayama F, Tanabe K, Ni J, Hayashu Y, Yamamoto K, Wu Z, Nakanishi H
    • Journal Title

      10.1007/s10571-016-0376-x.

      Volume: 37 Issue: 3 Pages: 437-443

    • DOI

      10.1007/s10571-016-0376-x

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
  • [Journal Article] Cathepsin B plays a critical role in inducing Alzheimer’s disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice2017

    • Author(s)
      Wu Zhou、Ni Junjun、Liu Yicong、Teeling Jessica L.、Takayama Fumiko、Collcutt Alex、Ibbett Paul、Nakanishi Hiroshi
    • Journal Title

      Brain, Behavior, and Immunity

      Volume: 65 Pages: 350-361

    • DOI

      10.1016/j.bbi.2017.06.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11478, KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848
  • [Journal Article] An EP2 agonist facilitates NMDA-induced outward currents and inhibits dendritic beading through activation of BK channels in mouse cortical neurons.2016

    • Author(s)
      Hayashi Y, Morinaga S, Liu X, Zhang J, Wu Z, Yokoyama T, Nakanishi H
    • Journal Title

      Mediators Inflamm

      Volume: 2016 Pages: 5079597-5079597

    • DOI

      10.1155/2016/5079597

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
  • [Journal Article] Cathepsin B regulates collagen expression by fibroblasts via prolonging TLR2/NF-kB activation.2016

    • Author(s)
      Li X, Wu Z, Ni J, Liu Y, Meng J, Yu W, Nakanishi H, Zhou Y
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2016 Issue: 1 Pages: 7894247-7894247

    • DOI

      10.1155/2016/7894247

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11478
  • [Journal Article] Nutrient, microglia aging, and brain aging.2016

    • Author(s)
      Wu Z, Yu J, Zhu A, Nakanishi H
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2016 Issue: 1 Pages: 7498528-7498528

    • DOI

      10.1155/2016/7498528

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11478
  • [Journal Article] Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.2016

    • Author(s)
      Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 30006-30006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Journal Article] BK channels in microglia are required for2016

    • Author(s)
      Yoshinori Hayashi, Saori Morinaga, Jing Zhang, Yasushi Satoh, Andrea Meredith, Takahiro Nakata, Zhou Wu, Shinichi Kohsaka, Kazuhide Inoue, Hiroshi Nakanishi
    • Journal Title

      Nature communications

      Volume: 7 Issue: 1 Pages: 11697-11697

    • DOI

      10.1038/ncomms11697

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04970, KAKENHI-PUBLICLY-16H01340, KAKENHI-PLANNED-25117009, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
  • [Journal Article] Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.2016

    • Author(s)
      Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 30006-30006

    • DOI

      10.1038/srep30006

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
  • [Journal Article] The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells2015

    • Author(s)
      Aiqin Zhu, Zhou Wu, Jie Meng, Patrick L. McGeer, Yi Zhu, Hiroshi Nakanishi, and Shizheng Wu
    • Journal Title

      Oxidative Medicine and Cellular Longevity

      Volume: 2015 Pages: 1-10

    • DOI

      10.1155/2015/792342

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
  • [Journal Article] Downward spiral of periodontitis and diabetes into Alzheimer's disease: Extending healthy life expectancy through oral health. J2015

    • Author(s)
      Hiroshi Nakanishi, Zhou Wu
    • Journal Title

      J Oral Biosci

      Volume: 57 Pages: 139-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Journal Article] The downwardspiralofperiodontitisanddiabetesinAlzheimer's disease: Extendinghealthylifeexpectancythroughoralhealth2015

    • Author(s)
      Hiroshi Nakanishi, Zhou WU
    • Journal Title

      Journal of Oral Biosciences

      Volume: 57 Issue: 3 Pages: 139-142

    • DOI

      10.1016/j.job.2015.05.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Journal Article] Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier2015

    • Author(s)
      Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
    • Journal Title

      Molecular and Cellular Neuroscience

      Volume: 64 Pages: 51-60

    • DOI

      10.1016/j.mcn.2014.12.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-26861555, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
  • [Journal Article] The Critical Role of Proteolytic Relay through Cathepsins B and E in the Phenotypic Change of Microglia/Macrophage2015

    • Author(s)
      XJunjun Ni, Zhou Wu, Christoph Peterts, Kenji Yamamoto, Hong Qing, and Hiroshi Nakanishi2015
    • Journal Title

      Journal of Neuroscience

      Volume: 35 Issue: 36 Pages: 12488-12501

    • DOI

      10.1523/jneurosci.1599-15.2015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
  • [Journal Article] Lessons from Microglia Aging for the Link between Inflammatory Bone Disorders and Alzheimer’s Disease2015

    • Author(s)
      Zhou Wu, Hiroshi Nakanishi
    • Journal Title

      Journal of Immunology Research

      Volume: 2015 Pages: 471342-471342

    • DOI

      10.1155/2015/471342

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
  • [Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2014

    • Author(s)
      Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
    • Journal Title

      J Neurosci

      Volume: 34 Pages: 3013-3022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Journal Article] Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance.2014

    • Author(s)
      Hayashi Y, Koga Y, Zhang X, Peters C, Yanagawa Y, Wu Z, Yokoyama T, Nakanishi H.
    • Journal Title

      Neuroscience

      Volume: 275 Pages: 384-94

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Journal Article] Connection Between Periodontitis and Alzheimer’s Disease: Possible Roles of Microglia and Leptomeningeal Cells2014

    • Author(s)
      Zhou Wu, Hiroshi Nakanishi
    • Journal Title

      J Pharmacol Sci

      Volume: 126 Issue: 1 Pages: 8-13

    • DOI

      10.1254/jphs.14R11CP

    • NAID

      130004684880

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Journal Article] Connection between periodontitis and Alzheimer's disease: possible roles of microglia and leptomeningeal cells.2014

    • Author(s)
      Wu Z, Nakanishi H.
    • Journal Title

      J Pharmacol Sci.

      Volume: 126 Pages: 8-13

    • NAID

      130004684880

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state.2014

    • Author(s)
      Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
    • Journal Title

      J Neurosci

      Volume: 34 Pages: 3013-3022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Journal Article] Novel roles of microglia2014

    • Author(s)
      Hiroshi Nakanishi
    • Journal Title

      Clinical & Experomental Neuroimmunology

      Volume: 5 Issue: s1 Pages: 35-40

    • DOI

      10.1111/cen3.12161

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Journal Article] Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance2014

    • Author(s)
      Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
    • Journal Title

      Neuroscience

      Volume: 275 Pages: 384-394

    • DOI

      10.1016/j.neuroscience.2014.06.037

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24791979
  • [Journal Article] Periphera1 ro1e of cathepsin S in Thl ce11-dependent transition of nerve injury-induced acute pain to a chronic pain state2014

    • Author(s)
      Xinwen Zhang,Zhou Wu,Yoshinori ayashi,Ryo Okada R,iroshi Nakanishi
    • Journal Title

      J Neurosci

      Volume: Vo1 34,No. 8 Pages: 3013-3022

    • Data Source
      KAKENHI-PROJECT-24659827
  • [Journal Article] Differential pathways for interleukin-1b production activated by chromogranin A and amyloid β in microglia2013

    • Author(s)
      Zhou Wu, Li Sun, Sadayuki Hashioka, Yu S, Schwab C, Ryo Okada, Yoshinori Hayashi, Patrick L McGeer PL, Hiroshi Nakanishi
    • Journal Title

      Neurobiol Aging

      Volume: 34 Issue: 12 Pages: 2715-2725

    • DOI

      10.1016/j.neurobiolaging.2013.05.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
  • [Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013

    • Author(s)
      Fumiko Takayama, Zhou Wu, Hong Ma HM, Okada R, Yoshinori Hayashi, Hiroshi Nakanishi
    • Journal Title

      J Neuroimmunol

      Volume: 262 Issue: 1-2 Pages: 121-124

    • DOI

      10.1016/j.jneuroim.2013.06.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
  • [Journal Article] Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-kB activation in microglia2013

    • Author(s)
      Zhou Wu, Aiqin Zhu, Fumiko Takayama, Ryo Okada, Yicong Liu, Yuka Harada, Shizheng Wu, Hiroshi Nakanishi
    • Journal Title

      Oxid Med Cell Longev

      Volume: 2013:906726 Pages: 1-10

    • DOI

      10.1155/2013/906726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
  • [Journal Article] Leptomeningeal cells transduce peripheral macrophages inflammatory signal to microglia in response to Porphyromonas gingivalis LPS2013

    • Author(s)
      Yicong Liu, Zhou Wu, Xinwen Zhang, Junjun Ni, Weixian Yu, Yanmin Zhou, Hiroshi Nakanishi
    • Journal Title

      Mediators Inflamm

      Volume: 2013:407562 Pages: 1-11

    • DOI

      10.1155/2013/407562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
  • [Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2013

    • Author(s)
      Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
    • Journal Title

      J Neurosci

      Volume: 34 Pages: 3013-3022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Journal Article] Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation2012

    • Author(s)
      Liu X, Wu Z, Hayashi Y, Nakanishi H
    • Journal Title

      Neuroscience

      Volume: 216 Pages: 133-142

    • DOI

      10.1016/j.neuroscience.2012.04.050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
  • [Journal Article] Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-induced Chronic Pain.2012

    • Author(s)
      S. Li, Z. Wu, Y. Hayashi, C. Peters, K. Inoue, M. Tsuda, and H. Nakanishi.
    • Journal Title

      J.Neurosci.

      Volume: 32(33) Issue: 33 Pages: 11330-42

    • DOI

      10.1523/jneurosci.0677-12.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
  • [Journal Article] Phosphatidylserine-containing liposomes : potential pharmacological interventions against inflammatory and immune diseases through the production of prostaglandin E_2 after uptake by myeloid derived phagocytes2011

    • Author(s)
      Wu Z, Nakanishi H
    • Journal Title

      Ach.Immunol.Therap.Exp. 59

      Pages: 196-201

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Phosphatidylserine -containing liposomes : potential pharmacological interventions against inflammatory and immune diseases through the production of prostaglandin E_2 after uptake by myeloid derived phagocytes2011

    • Author(s)
      Wu Z, Nakanishi H
    • Journal Title

      Ach.Immunol.Therap.Exp. 59

      Pages: 196-201

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2010

    • Author(s)
      Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H.
    • Journal Title

      Glia. 58(1)

      Pages: 114-124

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Phosphatidylserine-containing liposomes inhibit the differentiation of osteoclasts and trabecular bone loss.2010

    • Author(s)
      Wu Z, Ma HM, Kukita T, Nakanishi Y, Nakanishi H.
    • Journal Title

      J Immunol. 15;184(6)

      Pages: 3191-3201

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Phosphatidylserine-containing liposomes inhibit the differentiation of osteoclasts and trabecular bone loss.2010

    • Author(s)
      Wu Z, Ma HM, Kukita T, Nakanishi Y, Nakanishi H.
    • Journal Title

      J Immunol. 15;184(6)

      Pages: 3191-3201

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Acute p38-mediated inhibition of NMDA-induced outward currents in hippocampal CA1 neurons by interleukin-1β.2010

    • Author(s)
      Zhang R, Sun L, Hayashi Y, Liu X, Koyama S, Wu Z, Nakanishi H.
    • Journal Title

      Neurobiol Dis. 38(1)

      Pages: 68-77

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2010

    • Author(s)
      Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H.
    • Journal Title

      Glia. 58(1)

      Pages: 114-124

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Acute p38-mediated inhibition of NMDA-induced outward currents in hippocampal CA1 neurons by interleukin-1β.2010

    • Author(s)
      Zhang R, Sun L, Hayashi Y, Liu X, Koyama S, Wu Z, Nakanishi H.
    • Journal Title

      Neurobiol Dis. 38(1)

      Pages: 68-77

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.2010

    • Author(s)
      Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H.
    • Journal Title

      Biochem Biophys Res Commun. 399(3)

      Pages: 391-395

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.2010

    • Author(s)
      Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H.
    • Journal Title

      Biochem Biophys Res Commun. 399(3)

      Pages: 391-395

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Microglia-aging : Roles of microglial lysosomal- and mithochndria-derived reactive oxygen species in brain aging2009

    • Author(s)
      Nakanishi H, Wu Z
    • Journal Title

      Behavioral Brain Research 201

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Microglia-aging : Roles of microglial lysosomal- and mithochndria-derived reactive oxygen species in brain aging2009

    • Author(s)
      Nakanishi H , Wu Z
    • Journal Title

      Behavioral Brain Research 201

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008

    • Author(s)
      Zhang R, Yamada J, Hayashi Y, Wu Z, Koyama S, Nakanishi H.
    • Journal Title

      Biochem.Biophys.Res.Commun. 372

      Pages: 816-820

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Reduced synaptic acticity precedes synaptic stripping in vagal motoneurons after axotomy2008

    • Author(s)
      Yamada J., Hayashi Y., Jinno S., Wu Z., Inoue K., Kohsaka S., Nakanishi H.
    • Journal Title

      Glia 56

      Pages: 1448-1462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Reverse of brain aging by an overexpression of human mitochondrial transcription factor A in mice.2008

    • Author(s)
      Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H.
    • Journal Title

      J.Neurosci. 28

      Pages: 8624-8634

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Reverse of brain aging by an overexpression of human mitochondrial transcription factor A in mice.2008

    • Author(s)
      Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H.
    • Journal Title

      J.Neurosci. 28

      Pages: 8624-8634

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Reduced synaptic acticity precedes synaptic stripping in vagal motoneurons after axotomy.2008

    • Author(s)
      Yamada J, Hayashi Y, Jinno S, Wu Z, Inoue K, Kohsaka S, Nakanishi H.
    • Journal Title

      Glia 56

      Pages: 1148-1462

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Age-dependent responses of glial cells and leptomeninges during systemic inflammation2008

    • Author(s)
      Wu Z., Tokuda Y., Zhang X. W., and Nakanishi H.
    • Journal Title

      Neurobiol. Disease 32

      Pages: 543-551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rats.2008

    • Author(s)
      Sakamoto M, Miyamoto KI, Wu Z, Nakanishi H.
    • Journal Title

      Neurosci.Lett. 442

      Pages: 292-296

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons. Biochem.2008

    • Author(s)
      Zhang R, Yamada J, Hayashi Y, Wu Z, Koyama S, Nakanishi H.
    • Journal Title

      Biophys.Res.Commun. 372

      Pages: 816-820

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Possible involvement of cathepsin B released by microglia in methylmercury -induced cerebellar pathological changes in the adult rats.2008

    • Author(s)
      Sakamoto M, Miyamoto KI, Wu Z, Nakanishi H.
    • Journal Title

      Neurosci.Lett. 442

      Pages: 292-296

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rats2008

    • Author(s)
      Sakamoto M., Miyamoto K. I., Wu Z., and Nakanishi H
    • Journal Title

      Neurosci. Lett 442

      Pages: 292-296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons2008

    • Author(s)
      Zhang R., Yamada J., Hayashi Y., Wu Z., Koyama S., Nakanishi H
    • Journal Title

      Biochem. Biophys. Res. Commun 372

      Pages: 816-820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Reduced synaptic acticity precedes synaptic stripping in vagal motoneurons after axotomy.2008

    • Author(s)
      Yamada J, Hayashi Y, Jinno S, Wu Z, Inoue K, Kohsaka S, Nakanishi H.
    • Journal Title

      Glia 56

      Pages: 1148-1462

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Age-dependent responses of glial cells and leptomeninges during systemic inflammation.2008

    • Author(s)
      Wu Z, Tokuda Y, Zhang XW, Nakanishi H.
    • Journal Title

      Neurobiol.Disease 32

      Pages: 543-551

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Journal Article] Reverse of brain aging by an overexpression of human mitochondrial transcription factor A in mice2008

    • Author(s)
      Hayashi Y., Yoshida M., Yamato M., Ide T., Wu Z., Ochi-Shindou M., Kanki T. Kang D., Sunagawa K., Tsutsui H., and Nakanishi H.
    • Journal Title

      J. Neurosci 28

      Pages: 8624-8634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Age-dependent responses of glial cells and leptomeninges during systemic inflammation.2008

    • Author(s)
      Wu Z, Tokuda Y, Zhang XW, Nakanishi H.
    • Journal Title

      Neurobiol.Disease 32

      Pages: 543-551

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation2007

    • Author(s)
      Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi H., Kanba, S
    • Journal Title

      Free Rad. Biol. Med 42

      Pages: 945-954

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia.2007

    • Author(s)
      Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi, H., Kanba, S
    • Journal Title

      Neurochem. Int. 50

      Pages: 499-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid 13 and interferon-y-induced microglial activation.2007

    • Author(s)
      Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi, H., Kanba, S
    • Journal Title

      Free Rad. Biol. Med. 42

      Pages: 945-954

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] Involvement of PGE2 released from leptomeningeal cells in increased expression of TGF-β1 in glial cells and cortical neurons during systemic inflammation2007

    • Author(s)
      Wu Z., Hayashi Y. Zhang J., and Nakanishi H.
    • Journal Title

      J. Neurosci. Res 85

      Pages: 184-192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice2007

    • Author(s)
      Yamasaki R., Zhang J., Koshiishi I., Sastradipura Suniarti D.F.,Wu Z., Peters C., Schwake M., UchiyamaY., Kira J. I., Saftig P., Utsumi H., and Nakanishi H.
    • Journal Title

      Mol. Cell. Neurosci 35

      Pages: 573-584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Involvement of PGE2 released from leptomeningeal cells in increased expression of TGF-β1 in glial cells and cortical neurons during systemic inflammation2007

    • Author(s)
      Wu, Z., Hayashi, Y., Zhang, J., Nakanishi, H
    • Journal Title

      J. Neurosci. Res 85

      Pages: 184-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia2007

    • Author(s)
      Hashioka S., Han Y. H., Fujii S., Kato H., Monji A., Utsumi H., Sawada M., Nakanishi H., and Kanba S.
    • Journal Title

      Neurochem. Int 50

      Pages: 499-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Impairment of the microglial responses to the facial nerve axotomy in cathepsin S-deficient mice2007

    • Author(s)
      Hao H. P., Doh-ura K, and Nakanishi H.
    • Journal Title

      J. Neurosci. Res 85

      Pages: 2196-2206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Impairment of the microglial responses to the facial berve axotomy in cathepsin S-deficient mice.2007

    • Author(s)
      Hao, H.P., Doh-ura, K, Nakanishi, H
    • Journal Title

      J. Neurosci. Res. 85

      Pages: 2196-2206

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] Involvement of lysosomal storage- induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice2007

    • Author(s)
      Yamasaki, R., Zhang, J., Koshiishi, I., Sastradipura, D., Suniarti, F., Wu, Z., Peters, C., Schwake, M., Uchiyama, Y., Kira, J.-I., Saftig, P., Utsumi, H., Nakanishi, H
    • Journal Title

      Mol. Cell. Neurosci 35

      Pages: 573-584

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Impairment of the microglial responses to the facial berve axotomy in cathepsin S-deficient mice2007

    • Author(s)
      Hao, H.P., Doh-ura, K., Nakanishi, H
    • Journal Title

      J. Neurosci. Res 85

      Pages: 2196-2206

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice.2007

    • Author(s)
      Yamasaki, R., Zhang, J., Koshiishi, I., Sastradipura Suniarti, D.F., Wu, Z., Peters, C., Schwake, M., Uchiyama, Y., Kira, J.-I., Saftig, P., Utsumi, H., Nakanishi, H
    • Journal Title

      Mol. Cell. Neurosci. 35

      Pages: 573-584

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] Phospholipids modulate superoxide and nitric oxide production by lipopolysaccharide and phorbol 12-myristate-13-acetate-activated microglia2007

    • Author(s)
      Hashioka, S., Han, Y-H., Fujii, S., Kato, H., Monji, A., Utsumi, H., Sawada, M., Nakanishi. H., Kanba, S
    • Journal Title

      Neurochem. Int 50

      Pages: 499-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Phosphatidylserine and phosphatidylcholine- containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation2007

    • Author(s)
      Hashioka S., Han Y. H., Fujii S., Kato H., Monji A., Utsumi H., Sawada M., Nakanishi H., and Kanba S.
    • Journal Title

      Free Rad. Biol. Med 42

      Pages: 945-954

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Journal Article] Involvement of PGE_2 released from leptomeningeal cells in increased expression of TGF-β1 in glial cells and cortical neurons during systemic inflammation.2007

    • Author(s)
      Wu, Z., Hayashi, Y., Zhang, J., Nakanishi, H
    • Journal Title

      J. Neurosci. Res. 85

      Pages: 184-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] Cell cycle-dependent regulation of kainate-induced inward currents in microglia2006

    • Author(s)
      Yamada, J., Sawada, M., Nakanishi, H
    • Journal Title

      Biochem. Biophys. Res. Commun 349

      Pages: 913-919

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E2 production of microglia.2006

    • Author(s)
      Zhang, J., Fujii, S., Hashioka, S., Tanaka, Y., Wu, Z., Shiratsuchi, A., Nakanishi, Y., Nakanishi, H
    • Journal Title

      J. Neuroimmunol. 172

      Pages: 112-120

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats.2006

    • Author(s)
      Hayashi, Y., Tomimatsu, Y., Suzuki, H., Yamada, J., Yao, H., Kagamiishi, Y., Tateishi, N., Sawada, M., Nakanishi, H
    • Journal Title

      Neuroscience 142

      Pages: 87-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] Cell cycle-dependent regulation of kainate-induced inward currents in microglia.2006

    • Author(s)
      Yamada, J., Sawada, M., Nakanishi, H
    • Journal Title

      Biochem. Biophys. Res. Commun. 349

      Pages: 913-919

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Journal Article] The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats2006

    • Author(s)
      Hayashi, Y., Tomimatsu, Y., Suzuki, H., Yamada, J., Yao, H., Kagamiishi, Y., Tateishi, N., Sawada, M., Nakanishi, H
    • Journal Title

      Neuroscience 142

      Pages: 87-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Involvement of COX-1 and up-regulated prostaglandin E synthases in phosphatidylserine liposome-induced prostaglandin E_2 production of microglia2006

    • Author(s)
      Zhang, J., Fujii, S., Hashioka, S., Tanaka, Y., Wu, Z., Shiratsuchi, A., Nakanishi, Y., Nakanishi, H
    • Journal Title

      J. Neuroimmunol 172

      Pages: 112-120

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Leptomeningeal cells activate microglial and astrocytes to induce IL-10 production by releasing pro-inflammatory cytokines during systemic inflammation2005

    • Author(s)
      Wu, Z., Zhang, J., Nakanishi, H
    • Journal Title

      J. Neuroimmunol 167

      Pages: 90-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Amyloid-β fibril formation is not necessarily required for microglial activation by the peptides2005

    • Author(s)
      Hashioka, S., Monji, A., Ueda, T., Kanba, S., Nakanishi, H
    • Journal Title

      Neurochem. Int 47

      Pages: 369-376

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice2005

    • Author(s)
      Shimizu, T., Hayashi, Y., Yamasaki, R., Yamada, J., Zhang, J., Ukai, K., Koike, M., Mine, K., von Figura, K., Peters, C., Saftig, P., Fukuda, T., Uchiyama, Y., Nakanishi, H
    • Journal Title

      J. Neurochem 94

      Pages: 680-690

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Proteases and synaptic activity.In:Proteases2005

    • Author(s)
      Nakanishi H.(分担)
    • Journal Title

      Biology and Disease.Vol.3, (Eds:Lendeckel, U.and Hooper, N.), Kluwer Academic/Plenum Publishers

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Journal Article] Microglia-aging : Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging. Behav.

    • Author(s)
      Nakanishi H, Wu Z.
    • Journal Title

      Brain Res.

    • Data Source
      KAKENHI-PROJECT-20390472
  • [Journal Article] Microglia-aging : Roles of microglial lysosome- and mitochondria -derived reactive oxygen species in brain aging.

    • Author(s)
      Nakanishi H, Wu Z.
    • Journal Title

      Behav.Brain Res.

    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ノルアドレナリンのジンジバリス菌リポ多糖類ならびに外膜ベシクルによるミクログリアにおけるIL-1beta産生に及ぼす作用の解析2023

    • Author(s)
      城美紗桃、清水咲至、宮本彩也華、白川澄香、村本桜、森本千陽、竹森佑月、池田穂乃花、齋藤秀俊、中西博
    • Organizer
      第62回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] ジンジバリス菌由来リポ多糖類(LPS)刺激によるミクログリアにおけるIL-1beta産生に対するbeta-ディフェンシン3の抑制メカニズムの解析2023

    • Author(s)
      井上瑛里加、湊崎紫陽、小田康祐、野中さおり、中西博
    • Organizer
      第144回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] Gingipains from P. gingivalis destroy blood-brain barrier and intestinal barrier through intracellular degradation of tight junction proteins2023

    • Author(s)
      Nonaka S, Tochigi S, Okamoto R, Nakanishi H.
    • Organizer
      11th IBRO World Congress of Neuroscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] ジンジバリス菌リポ多糖類(LPS)ならびに外膜ベシクル(OMV)によるミクログリアにおけるIL-1beta産生経路の解明2023

    • Author(s)
      宮本彩也華、井上瑛里加、清水咲至、城美紗桃、湊崎紫陽、齋藤秀俊、小田康祐、 野中さおり、中西博
    • Organizer
      第62回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] 主要な歯周病菌「ジンジバリス菌」が分泌する外膜ベシクル(OMV)による脳ならびに腸バリア機能の破綻メカニズムの解明2023

    • Author(s)
      野中さおり、中西博
    • Organizer
      第144回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] ジンジバリス菌が分泌する外膜小胞による腸上皮バリア破綻機構2023

    • Author(s)
      野中さおり、岡本凜、勝田結衣、金築志織、中西博
    • Organizer
      第96回日本生化学会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] beta-ディフェンシン3のジンジバリス菌リポ多糖類ならびに外膜ベシクルによるミクログリアにおけるIL-1bbeta産生に及ぼす作用の解析2023

    • Author(s)
      清水咲至、井上瑛里加、宮本彩也華、城美紗桃、湊崎紫陽、齋藤秀俊、野中さおり、 小田康祐、中西博
    • Organizer
      第62回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] ヒト beta-ディフェンシン-3の歯周病菌LPSにより誘発されるミクログリアの酸化ストレスならびに炎症反応に対する抑制作用2022

    • Author(s)
      崎紫陽、井上瑛里加、野中さおり、中西博
    • Organizer
      第61回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] 歯周病菌LPSによりミクログリアにおいて産生・分泌されるサイトカイン類の網羅的解析2022

    • Author(s)
      大森朱莉、大本凜、野中さおり、中西博
    • Organizer
      第61回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] ヒト beta-ディフェンシン-3の歯周病菌LPSにより誘発されるミクログリアの酸化ストレス・炎症反応に対する抑制メカニズム2022

    • Author(s)
      井上瑛里加、湊崎紫陽、野中さおり、中西博
    • Organizer
      第61回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-21K06383
  • [Presentation] アルツハイマー病治療のパラダイムシフト -歯周病とミクログリアの不都合な関係-2020

    • Author(s)
      中西 博
    • Organizer
      第142回日本薬学会中国四国支部例会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] Involvement of endosomal signaling in gingipain-induced migration, inflammation response and phagocytosis in microglia after activation of PAR2、2019

    • Author(s)
      Nonaka S, Iseki A, Amano A, Nakanishi Y, Ni J, Wu Z, Nakanishi H.
    • Organizer
      XIV European meeting on glial cells in health and disease (GLIA 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] Secreted gingipains from Porphyromonas gingivalis induce microglia migration through endosomal signaling by protease-activated receptor 22019

    • Author(s)
      Nonaka S, Nakanishi H.
    • Organizer
      第24回グリア研究会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] Cathepsin H deficiency suppresses hypoxic-ischemia-induced hippocampal atrophy in mice through reduced secretion of IFN-beta from microglia2019

    • Author(s)
      Ni J, Wu Z, Nakanishi H,
    • Organizer
      第24回グリア研究会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain2019

    • Author(s)
      Junjun Ni、中西 博 、武 洲
    • Organizer
      第72回日本薬理学会西南部会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] カテプシン群と痛みの治療2019

    • Author(s)
      中西 博
    • Organizer
      第18回痛みの研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] 脊髄ミクログリアBKチャネルの神経障害性疼痛における役割2019

    • Author(s)
      佐藤泰司、諸橋 徹、林 良憲、板倉沙也子、川口慎憲、中西 博、メレディス アンドレア、石塚 俊晶
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] ミクログリアにおけるカテプシン増大と細胞内の分布変化は、酸化ストレスならびに炎症反応を介して認知障害をもたらす2018

    • Author(s)
      Junjuin Ni、武 洲、林 良憲、中西 博
    • Organizer
      第71回日本薬理学会西南部会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] チベット薬Ratanasampilは低酸素によるミクログリアにおける酸化ストレスならびにNF-kappaB活性化に依存した炎症反応を抑制する2018

    • Author(s)
      Jie Meng、Junjun Ni、林 良憲、中西 博、朱 愛琴、武 洲
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] ITPA欠損によるヒトてんかん性脳症のモデルとしての神経幹細胞特異的Itpaノックアウトマウス2018

    • Author(s)
      土本大介、古賀祐一郎、林 良憲、アボルハッサニ ノナ、米嶋康臣、中西 博、中別府雄
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] チベット薬Ratanasampilは、低酸素によるミクログリアにおける酸化ストレスならびにNF-kappaB活性化に依存した炎症反応を抑制する2018

    • Author(s)
      孟ジェイ、朱愛琴、Junjuin Ni、林 良憲、中西 博、武 洲
    • Organizer
      第71回日本薬理学会西南部会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] ブラジル産グリーンプロポリスは、チベット高原に住む高齢者の全身炎症を軽減して認知機能の低下を防ぐ2018

    • Author(s)
      Zhu A, Ni J, Meng J, Nakanishi H ,Wu Z
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Involvement of reduced microglial BMAL1 expression in excessive neuroinflammation of APP knock-in (APP-KI) mice.2018

    • Author(s)
      Ni J, Wu Z, Nonaka S, Saido TC, Nakanishi H
    • Organizer
      第23回グリア研究
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] ミクログリアにおけるカテプシンBの発現増加及び細胞内分布変化はマウスにおける酸化ストレスや炎症反応による認知障害を誘発する2018

    • Author(s)
      Junjun Ni、武 洲、林 良憲、中西 博
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] チベット薬Ratanasampilは、低酸素によるミクログリアにおける酸化ストレスならびにNF-κB活性化に依存した炎症反応を抑制する2018

    • Author(s)
      Jie Meng, Junjun Ni, Yoshinori Hayashi, Hiroshi Nakanishi, Aiqin Zhu and Zhou Wu
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Porphyromonas gingivalis 菌慢性末梢感染により老齢femaleマウスミクログリアにおける抗炎症能が低下する2018

    • Author(s)
      中西 悠梨香
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] ブラジル産グリーンプロポリスはチベット高原に住む高齢者の全身炎症を軽減して認知機能の低下を防ぐ2018

    • Author(s)
      朱 愛琴、Junjun Ni、Jie Meng、中西 博、武 洲
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K19650
  • [Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第59回歯科基礎医学会学術大会 学術シンポジウム
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] 歯周病と認知症:増悪機構の解明と今後の展望2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第90本薬理学会年会 年会企画シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] 歯周病と認知機能:増悪機序の解明と今後の展望2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第90回日本薬理学会年会(年会企画シンポジウム:口腔ブレインサイエンスに学ぶ健康長寿)
    • Place of Presentation
      長崎新聞文化ホール(長崎)
    • Year and Date
      2017-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Rheum tanguticum in activated microglia.2017

    • Author(s)
      Meng J, Ni J, Wu Z, Zhu A, Nakanishi H
    • Organizer
      第90回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] 口内を清潔に保って認知症を防げ2017

    • Author(s)
      中西 博
    • Organizer
      新学術領域「グリアアセンブリ」公開シンポジウム
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response of microglia through the gingipain-mediated activation of protease-activated receptor-2.2017

    • Author(s)
      Liu Y, Wu Z, Nakanishi H
    • Organizer
      第22回グリア研究会
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Increased expression and altered subcellular distribution of cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging.2017

    • Author(s)
      Ni J, Wu Z, Nakanishi H
    • Organizer
      第22回グリア研究会
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Gingipain Induce Microglia Migration through activation of protease-activated receptor-2. 95th Annuak Meeting of International Association for Dental Research2017

    • Author(s)
      Yicong Liu , Zhou Wu and Hiroshi Nakanishi
    • Organizer
      IADR 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] 8The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-22017

    • Author(s)
      Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017

    • Author(s)
      Yicong Liu, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      95tth Annual Meeting of International Association for Dental Research (IADR2017)
    • Place of Presentation
      サンフランシスコ(USA)
    • Year and Date
      2017-03-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease- activated receptor-2 (PAR-2).2017

    • Author(s)
      Liu Y, Wu Z, Kadowaki T, Nakanishi H
    • Organizer
      第90本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2).2017

    • Author(s)
      Liu Y, Wu Z, Kadowaki T, Nakanishi H
    • Organizer
      第90本薬理学会年会
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] 歯周病菌によるアルツハイマー様脳病態の発症と原因酵素としてのカテプシン群の役割2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第59回歯科基礎医学会学術大会 学術シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] 皮膚ケラチノサイトのカテプシンEを介した神経障害性疼痛の慢性化メカニズムの解明2017

    • Author(s)
      張 競、林 良憲、中西 博
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)、2017

    • Author(s)
      Yicong Liu, Zhou Wu, Hiroshi Nakanishi,
    • Organizer
      95tth Annual Meeting of International Association for Dental Research (IADR2017)
    • Place of Presentation
      サンフランシスコ(USA)
    • Year and Date
      2017-03-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017

    • Author(s)
      Yicong Liu, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      95tth Annual Meeting of International Association for Dental Research (IADR2017)
    • Place of Presentation
      サンフランシスコ(USA)
    • Year and Date
      2017-03-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Gingipains induce microglial migration through activation protease-activated receptor-2 (PAR-2).2017

    • Author(s)
      Liu Y, Wu Z, Nakanishi H
    • Organizer
      95th Annual Meeting of International Association for Dental Research (IADR2017)
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017

    • Author(s)
      Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] 口内を清潔に保って認知症を防げ2017

    • Author(s)
      中西 博
    • Organizer
      新学術領域「グリアアセンブリ」公開シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] L-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017

    • Author(s)
      Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017

    • Author(s)
      Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017

    • Author(s)
      Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] 歯周病と認知機能:増悪機序の解明と今後の展望2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第90回日本薬理学会年会(年会企画シンポジウム:口腔ブレインサイエンスに学ぶ健康長寿)
    • Place of Presentation
      長崎新聞文化ホール(長崎)
    • Year and Date
      2017-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Increased expression and altered subcellular distribution of Cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging2017

    • Author(s)
      Junjun Ni, Zhou Wu and Hiroshi Nakanishi
    • Organizer
      The 22nd Annual Meeting of Japan Glia
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] The critical roles of gingipains in cell migration and inflammatory response of microglia through activation of protease-activated receptor-2 (PAR-2)2017

    • Author(s)
      Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] 歯周病と認知機能:増悪機序の解明と今後の展望2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第90回日本薬理学会年会(年会企画シンポジウム:口腔ブレインサイエンスに学ぶ健康長寿)
    • Place of Presentation
      長崎新聞文化ホール(長崎)
    • Year and Date
      2017-03-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia、2017

    • Author(s)
      Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] 歯周病と認知機能:増悪機序の解明と今後の展望2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第90回日本薬理学会年会(年会企画シンポジウム:口腔ブレインサイエンスに学ぶ健康長寿)
    • Place of Presentation
      長崎新聞文化ホール(長崎)
    • Year and Date
      2017-03-17
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Rheum tanguticum in activated microglia.2017

    • Author(s)
      Meng J, Ni J, Wu Z, Zhu A, Nakanishi H
    • Organizer
      第90回日本薬理学会年会
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] 皮膚ケラチノサイトのカテプシンEを介した神経障害性疼痛の慢性化メカニズムの解明2017

    • Author(s)
      張 競、林 良憲、中西 博
    • Organizer
      第59回歯科基礎医学会学術大会 学術シンポジウム
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Gingipains induce microglial migration through activation of protease-activated receptor-2 (PAR-2)2017

    • Author(s)
      Yicong Liu, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      95tth Annual Meeting of International Association for Dental Research (IADR2017)
    • Place of Presentation
      サンフランシスコ(USA)
    • Year and Date
      2017-03-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] 歯周病と認知症:増悪機構の解明と今後の展望2017

    • Author(s)
      武 洲、中西 博
    • Organizer
      第90本薬理学会年会 年会企画シンポジウム
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Critical roles of cathepsin B in Alzheimer’s disease-like phenotypes following chronic systemic exposure to Porphyromonas gingivalis2017

    • Author(s)
      Zhou Wu Junjun Ni, Yicong Liu and Hiroshi Nakanishi
    • Organizer
      ISN-ESN Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] IL-10 plays a pivotal role in anti-inflammatory effects of Pheum tanguticum in activated microglia2017

    • Author(s)
      Jie Meng, Junjun Ni, Zhou Wu, Aiquin Zhu, Hiroshi Nakanishi
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response of microglia through the gingipain-mediated activation of protease-activated receptor-2.2017

    • Author(s)
      Liu Y, Wu Z, Nakanishi H
    • Organizer
      第22回グリア研究会
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Gingipains induce microglial migration through activation protease-activated receptor-2 (PAR-2).2017

    • Author(s)
      Liu Y, Wu Z, Nakanishi H
    • Organizer
      95th Annual Meeting of International Association for Dental Research (IADR2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-22017

    • Author(s)
      Yicong Liu, Zhou Wu and Hiroshi Nakanishi
    • Organizer
      The 22nd Annual Meeting of Japan Glia
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Increased expression and altered subcellular distribution of cathepsin B in microglia induces cognitive impairment through oxidative stress and inflammatory response during aging.2017

    • Author(s)
      Ni J, Wu Z, Nakanishi H
    • Organizer
      第22回グリア研究会
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2(PAR-2)の活性化を介したミクログリアの細胞遊走誘導2016

    • Author(s)
      劉 訳聡、武 洲、門脇知子、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016

    • Author(s)
      武 洲、中西 博
    • Organizer
      第58回歯科基礎医学会学術大会(サテライトシンポジウム:健康長寿社会を目指す口腔ブレインサイエンスの最前線)
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2016-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Pathological roles of microglial cathepsins in chronic pain2016

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      XVth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      ポートローズ、スロベニア
    • Year and Date
      2016-09-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016

    • Author(s)
      孟ジェイ、武 洲、門脇知子、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2(PAR-2)の活性化を介したミクログリアの細胞遊走誘導2016

    • Author(s)
      劉 訳聡、武 洲、朱 愛琴、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses,2016

    • Author(s)
      Junjun Ni, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2(PAR-2)の活性化を介したミクログリアの細胞遊走誘導2016

    • Author(s)
      劉 訳聡、武 洲、朱 愛琴、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses2016

    • Author(s)
      Junjun Ni, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Pathological roles of microglial cathepsins in chronic pain2016

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      XVth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      ポートローズ、スロベニア
    • Year and Date
      2016-09-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses,2016

    • Author(s)
      Junjun Ni, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016

    • Author(s)
      武 洲、中西 博
    • Organizer
      第58回歯科基礎医学会学術大会(サテライトシンポジウム:健康長寿社会を目指す口腔ブレインサイエンスの最前線)
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2016-08-24
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016

    • Author(s)
      Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016

    • Author(s)
      Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016

    • Author(s)
      孟ジェイ、武 洲、朱 愛琴、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016

    • Author(s)
      Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi,
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Possible involvement of cathepsin H in the negative regulation of T cell activation in experimental autoimmune encepalomyelitis (EAE)2016

    • Author(s)
      Ryo Okada, Yuka Harada, Zhou Wu, Ryo Yamasaki, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016

    • Author(s)
      武 洲、中西 博
    • Organizer
      第58回歯科基礎医学会学術大会(サテライトシンポジウム:健康長寿社会を目指す口腔ブレインサイエンスの最前線)
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2016-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05848
  • [Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016

    • Author(s)
      孟ジェイ、武 洲、門脇知子、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] ミクログリアにおけるIL-10産生分泌を介したRheum tanguticumの抗炎症作用2016

    • Author(s)
      孟ジェイ、武 洲、門脇知子、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Pathological roles of microglial cathepsins in chronic pain2016

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      XVth Symposium on Proteases, Inhibitors and Biological Control
    • Place of Presentation
      ポートローズ、スロベニア
    • Year and Date
      2016-09-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] 歯周病菌感染による脳内アルツハイマー様病態の誘発メカニズム2016

    • Author(s)
      武 洲、中西 博
    • Organizer
      第58回歯科基礎医学会学術大会(サテライトシンポジウム:健康長寿社会を目指す口腔ブレインサイエンスの最前線)
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2016-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Arg-ならびにLys-gingipainによるprotease-activated receptor-2(PAR-2)の活性化を介したミクログリアの細胞遊走誘導2016

    • Author(s)
      劉 訳聡、武 洲、朱 愛琴、中西 博
    • Organizer
      第69回日本薬理学会西南部会
    • Place of Presentation
      松山大学(愛媛)
    • Year and Date
      2016-11-26
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Microglia fascilitate brain aging and cognitive imairment through cathepsin B-dependent oxidative and inflammatory responses2016

    • Author(s)
      Junjun Ni, Zhou Wu, Hiroshi Nakanishi
    • Organizer
      第21回グリア研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪)
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PUBLICLY-16H01340
  • [Presentation] Modulator actions of microglial cathepsins in brain diseases2015

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      Cold Spring Harbor Asia(CSHA Conference 2015): New Insights into Glia Function & Dysfunction
    • Place of Presentation
      Worldhotel Grand Dushulake Suzhou
    • Year and Date
      2015-06-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Periodontitis and Alzheimer’s disease (AD) (1): A possible role of leptomeninges in transduction of inflammatory signals from peripheral macrophages to microglia in the response to lipopolyssacharide from Porphyromonas gingivalis2015

    • Author(s)
      Yicong Liu、Zhou Wu、 Hiroshi Nakanishi
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Modulator actions of microglial cathepsins in brain diseases2015

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      Cold Spring Harbor Asia(CSHA Conference 2015)
    • Place of Presentation
      Worldhotel Grand Dushulake Suzhou(中国、蘇州市)
    • Year and Date
      2015-06-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] ATPならびにPorphyromonas gingivalis(PG)局所注入により惹起されるミクログリア突起の集積とその日内変化に関する生体イメージング解析2015

    • Author(s)
      髙山扶美子、林 良憲、武 洲、中西 博
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ新潟(新潟)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] ATPならびにPorphyromonas gingivalis(PG)局所注入により惹起されるミクログリア突起の集積とその日内変化に関する生体イメージング解析2015

    • Author(s)
      髙山扶美子、林 良憲、武 洲、中西
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Lessons from cathepsin deficient mice on human brain diseases2015

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      The 4th International Conference and Exhibition on Neurology & Therapeutics
    • Place of Presentation
      Holiday Inn Rome Aurelia(ローマ)
    • Year and Date
      2015-07-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Critical roles of cathepsin B in AD-like phenotypes in middle-aged mice following chronic systemic treatment with lipopolyssacharide from Porphyromonas gingivalis2015

    • Author(s)
      Junjun Ni、Zhou Wu、 Hiroshi Nakanishi
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ新潟(新潟)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] Lessons from cathepsin deficient mice on human brain diseases2015

    • Author(s)
      Hiroshi Nakanishi
    • Organizer
      The 4th International Conference and Exhibition on Neurology & Therapeutics
    • Place of Presentation
      Holiday Inn Rome Aurelia
    • Year and Date
      2015-07-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Periodontitis and Alzheimer’s disease (AD) (2): Critical roles of cathepsin B in AD-like phenotypes in middle-aged mice following chronic systemic treatment with lipopolyssacharide from Porphyromonas gingivalis2015

    • Author(s)
      Junjun Ni、Zhou Wu、 Hiroshi Nakanishi
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      朱鷺メッセ新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K15684
  • [Presentation] Involvement of brain pericyte damage in neuropathological changes associated eith lysosomal storage2015

    • Author(s)
      Zhou Wu, Ryo Okada、Hiroshi Nakanishi
    • Organizer
      The 4th International Conference and Exhibition on Neurology & Therapeutics
    • Place of Presentation
      Holiday Inn Rome Aurelia(ローマ)
    • Year and Date
      2015-07-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05015
  • [Presentation] カテプシンSは告げんの日無い変化がもたらすミクログリアならびにニューロン機能の日内変化2014

    • Author(s)
      高山扶美子、林 良憲、武 洲、中西 博
    • Organizer
      第67回日本薬理学会西南部会
    • Place of Presentation
      産業医科大学ラマツィーニホール(福岡)
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] プロポリスのカテプシンS 発現制御を介したTh1 応答抑制作用2014

    • Author(s)
      張 馨文、武 洲、中西 博
    • Organizer
      第56回歯科基礎医学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] クログリアの2種類の突起の日内変化に関する形態学的ならびに生体イメージング解析2014

    • Author(s)
      髙山扶美子、林 良憲、武 洲、中西 博
    • Organizer
      第56回歯科基礎医学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Cathepsin B is a possible phenotype switch along the M1-M2 phenotypic continuum of microglia/macrophages2014

    • Author(s)
      倪 軍軍、武 洲、中西 博
    • Organizer
      第19回グリア研究会
    • Place of Presentation
      東京商工会議所(東京)
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Involvement of cathepsin S in the diurnal morphological and functional changes of cortical microglial processes2014

    • Author(s)
      高山扶美子、林良憲、武洲、中西博
    • Organizer
      第21回日本時間生物学会学術大会
    • Place of Presentation
      九州大学医学部百年講堂(福岡)
    • Year and Date
      2014-11-07
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014

    • Author(s)
      林 良憲、中西 博
    • Organizer
      研究会 「痛みと痛覚情動連関の神経機構」
    • Place of Presentation
      生理学研究所(岡崎)
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Cathepsin B is positive phenotype switch the M1-M2 phenotypic continuum of microglia/macrophages2014

    • Author(s)
      JunJun Ni、武 洲、中西 博
    • Organizer
      第19回グリア研究会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] 神経障害性疹痛の慢性化におけるカテプシンSの役割2014

    • Author(s)
      張馨文、武洲、林良憲、中西博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2014-03-19
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014

    • Author(s)
      林 良憲、中西 博
    • Organizer
      第67回日本薬理学会西南部会
    • Place of Presentation
      産業医科大学ラマツィーニホール(福岡)
    • Year and Date
      2014-11-23
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014

    • Author(s)
      林 良憲、中西 博
    • Organizer
      第19回グリア研究会
    • Place of Presentation
      東京商工会議所(東京)
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] カテプシンH欠損による実験的自己免疫性脳脊髄炎の発症促進とT細胞サブセットの変動2014

    • Author(s)
      岡田 亮、中西 博
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Microg1ia1 circadian c1ock contro1s microg1ia-synapse interactions in the hea1thy brain,in Symposium of"Why do microg1ia exist in the brain : As a target for treatment of neuro1ogica1 disorders"2013

    • Author(s)
      中西博
    • Organizer
      シンポジウム,第90回日本生理学会大会
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] クロモグラニンA(CGA)によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明2013

    • Author(s)
      武洲、中西博
    • Organizer
      第55回歯科基礎医学学術大会
    • Place of Presentation
      岡山コンベンションセンター
    • Year and Date
      2013-09-22
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Microg1ia1 circadian c1ock contro1s diurna1 changes in synaptic strength through microg1ia-synaptic interactions2013

    • Author(s)
      中西博
    • Organizer
      シンポジウム、Neuro20l3
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2013-06-21
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Potential roles of chromogranin A in cathepsin B-dependent IL-1βproduction by microglia in Alzheimer’s disease2013

    • Author(s)
      Wu Z, Nakanishi H
    • Organizer
      第86回日本薬理学会年会,
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013

    • Author(s)
      林 良憲, 中西 博
    • Organizer
      第86回日本薬理学会年会、シンポジウム:Roles of microglia and astrocytes in synaptic reotganization: New trends in glial research
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Regulation of microglia-synapse interactions and synaptic strength by microglial circadian clock2013

    • Author(s)
      林良憲, 中西博
    • Organizer
      第86回日本薬理学会年会、シンポジウム : Roles of microglia and astrocytes in synaptic reotganization : New trends in glial research
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013

    • Author(s)
      中西 博
    • Organizer
      第90回日本生理学会大会、シンポジウム:Why do microglia exist in the brain: As a terget for treatment of neurological disorders
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013

    • Author(s)
      中西博
    • Organizer
      第90回日本生理学会大会, シンポジウム : Why do microglia exist in the brain: As a terget for treatment of neurological disorders
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Batten病モデルマウスにおける脳ベリサイトの消失と血液脳関門の破綻2013

    • Author(s)
      岡田亮、武洲、見軍軍、中西博
    • Organizer
      第66回日本薬理学会西南部会
    • Place of Presentation
      福岡大学
    • Year and Date
      2013-11-16
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Regu1ation of microg1ia-synapse interactions and synaptic strength by microg1ia1 circadian c1ock,in Symposium of"Ro1es of microg1ia and astrocytes in synaptic reorganization : New trends in g1ia1 research"2013

    • Author(s)
      林良憲,中西博
    • Organizer
      シンポジウム,第86回日本薬理学会年会
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Cathepsin B-dependent novel IL-1β production pathway in microglia2013

    • Author(s)
      Wu Z, Nakanishi H,
    • Organizer
      Kudai Oral Bioscience 2013
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] ミクログリアの電気生理学的解析2012

    • Author(s)
      中西博
    • Organizer
      包括型脳科学研究推進支援ネットワーク・夏のワークショップ, 「グリア機能解析」チュートリアル
    • Place of Presentation
      仙台(招待講演)
    • Year and Date
      2012-07-27
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] クロモグラニンAの慢性炎症性疼痛における役割の解析2012

    • Author(s)
      孫麗, 武 洲, 林 良憲, 中西 博
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] ミクログリアの産生するカテプシン群の慢性疼痛における役割2012

    • Author(s)
      中西博
    • Organizer
      平成24年度生理研研究会「痛み研究の新たな展開」
    • Place of Presentation
      岡崎(招待講演)
    • Year and Date
      2012-12-13
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] ミクログリアの産生するカテプシン群の慢性疼痛における役割2012

    • Author(s)
      中西 博
    • Organizer
      平成24年度生理研研究会「痛み研究の新たな展開」
    • Place of Presentation
      岡崎
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] ミクログリアの電気生理学的解析2012

    • Author(s)
      中西博
    • Organizer
      包括型脳科学研究推進支援ネットワーク・夏のワークショップ,「グリア機能解析jチユートリアル
    • Place of Presentation
      仙台
    • Year and Date
      2012-07-27
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] ミクログリアの産生するカテプシン群の慢性疹痛における役割2012

    • Author(s)
      中西博
    • Organizer
      平成年度生理研研究会「痛み研究の新たな展開」
    • Place of Presentation
      岡崎(教育講演)
    • Year and Date
      2012-12-13
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] クロモグラニンAはβアミロイドよりも強力にミクログリアにおけるIL-1β産生を誘導する2012

    • Author(s)
      武 洲, 中西 博
    • Organizer
      第65回日本薬理学会西南部会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] NMDAレセプターとミクログリア, CINP・NP2012合同年会, シンポジウム: NMDAレセプター神経疾患の分子病態を探る2012

    • Author(s)
      中西 博
    • Organizer
      CINP・NP2012合同年会
    • Place of Presentation
      宇都宮
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] NMDAレセプターとミクログリア2012

    • Author(s)
      中西博,林良憲
    • Organizer
      CINP・NP20l2合同年会,シンポジウム: NMDAレセプター神経疾患の分子病態を探る
    • Place of Presentation
      宇都宮
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] NMDAレセプターとミクログリア2012

    • Author(s)
      中西博
    • Organizer
      CINP・NP2012合同年会, シンポジウム : NMDAレセプター神経疾患の分子病態を探る
    • Place of Presentation
      宇都宮(招待講演)
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Microglial circadian clock controls microglia-synapse interactions through P2Y12 receptors and cathepsin S expression2012

    • Author(s)
      中西 博
    • Organizer
      The 15th Annual Meeting of the Korean Society for Brain and Neural Science in Symposium of Glial Neuroscience
    • Place of Presentation
      ソウル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] 神経障害性疼痛におけるミクログリアのカテプシンSの関与2010

    • Author(s)
      張馨文、孫麗、武洲、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] ミクログリアの産生するカテプシンS の神経障害性疼痛発症における役割2010

    • Author(s)
      張馨文、林良憲、武洲、中西 博
    • Organizer
      第15回グリア研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] S-ketamine preferentially inhibits neuropathic pain through the neuronal-based and microglia-related mechanisms.2010

    • Author(s)
      Kawaji K, Hayashi Y, Nakanishi H
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      サンジエゴ
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Microglial cathepsin B : a strategic target for neuroprotective agents.2010

    • Author(s)
      Wu Z, Nakanishi H
    • Organizer
      BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010
    • Place of Presentation
      Shanghai
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 慢性末梢炎症によるミクログリア活性化と海馬LTPの障害2010

    • Author(s)
      劉霞、武洲、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 慢性末梢炎症によるミクログリア活性化と海馬LTP障害2010

    • Author(s)
      劉霞、武洲、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] A possible involvement of cathepsin B in nociceptive processing through the processing and secretion of interleukin-1 family from microglia.2010

    • Author(s)
      Sun L, Wu Z, Hayashi Y, Nakanishi H
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      サンジエゴ
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010

    • Author(s)
      武洲, 劉霞, 中西博
    • Organizer
      The 1^<st> International Congress on Controversies in Longevity, Health and Aging.
    • Place of Presentation
      バルセロナ
    • Year and Date
      2010-06-24
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] S-ketamine preferentially inhibits neuropathic pain through the neuronal-based and microglia-related mechanisms.2010

    • Author(s)
      河路広大, 林良憲, 中西博
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      サンジエゴ
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] カテプシンB阻害による疼痛制御2010

    • Author(s)
      中西博
    • Organizer
      第5回九大痛みの研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 神経障害性疼痛におけるミクログリアのカテプシンSの関与2010

    • Author(s)
      張馨文、孫麗、武洲、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 炎症性疼痛発症におけるミクログリアのカテプシンBの関与2010

    • Author(s)
      孫麗、武洲、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ホスファチジルセリンリポソームによる炎症性骨破壊抑制メカニズムの解析2010

    • Author(s)
      武洲、馬紅梅、久木田敏夫、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Preferential inhibitory effects of S-ketamine on neuropatic pain through both the neuronal based and microglia related mechanisms.2010

    • Author(s)
      Hayashi Y, Kawaji K, Nakanishi H
    • Organizer
      The 29^<th> Naito Conference : Glia World.
    • Place of Presentation
      湘南村
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Acute p38-mediated inhibition of K_Ca channels activated by Ca^<2+> influx through both NMDA receptor and voltage-gated Ca^<2+> channels by interleukin-1β2010

    • Author(s)
      Hayashi Y, Zhang R, Sun L, Wu Z, Nakanishi H
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      サンジエゴ
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] S-ケタミンのNMDA電流ならびにミクログリア活性化の優位阻害による神経障害性疼痛に対する抑制作用2010

    • Author(s)
      林良憲、河路広大、中西博
    • Organizer
      第63回日本薬理学会西南部会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ホスファチジルセリンリポソームによる骨形成の促進2010

    • Author(s)
      馬紅梅、武洲、李銀姫、久木田敏夫、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010

    • Author(s)
      武洲, 劉霞, 中西博
    • Organizer
      The 1^<st> International Congress on Controversies in Longevity, Health and Aging.
    • Place of Presentation
      バルセロナ
    • Year and Date
      2010-06-24
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 中年ルイスラットにおけるアジュバント関節炎に伴うミクログリア活性化と海馬長期増強の障害2010

    • Author(s)
      武洲、劉霞、中西博
    • Organizer
      第63回日本薬理学会西南部会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] S-ケタミンのNMDA電流ならびにミクログリア活性化の優位阻害による神経障害性疼痛に対する抑制作用2010

    • Author(s)
      林良憲、河路広大、中西博
    • Organizer
      第63 回日本薬理学会西南部会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] カテプシンB阻害による疼痛制御2010

    • Author(s)
      中西博
    • Organizer
      第5回九大痛みの研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-02-19
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Preferential inhibitory effects of S-ketamine on both NMDA receptor currents and neuropathic pain.2010

    • Author(s)
      Kawaji K, Hayshi Y, Koyano K, Yokoyama T, Nakanishi H
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010

    • Author(s)
      Wu, Liu X, Nakanishi H
    • Organizer
      The 1st International Congress on Controversies in Longevity, Health and Aging
    • Place of Presentation
      Barcelona
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] ホスファチジルセリンリポソームによる炎症性骨破壊抑制メカニズムの解析2010

    • Author(s)
      武洲、馬紅梅、久木田敏夫、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミクログリアのリソソーム・ミトコンドリア系を標的としたグリア創薬に可能性2010

    • Author(s)
      中西博
    • Organizer
      第130回日本薬学会年会、130回年会祈念融合型シンポジウム「グリア創薬の最前線と可能性」
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Protective effects of microglia-conditioned medium against NMDA-induced dendritic injury through an inhibition of non-selective cation conductance.2010

    • Author(s)
      Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Acute p38-mediated inhibition of K_Ca channels activated by Ca^<2+> influx through both NMDA receptor and voltage-gated Ca^<2+> channels by interleukin-1β2010

    • Author(s)
      Hayashi Y, Zhang R, Sun L, Wu Z, Nakanishi H.
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      サンジエゴ
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Neuroprotection of microglia-conditioned medium on excitotoxic neuronal injury through inhibition of large cation conductance.2010

    • Author(s)
      Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 炎症性疼痛発症におけるミクログリアのカテプシンBの関与2010

    • Author(s)
      孫麗、武洲、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] ホスファチジルセリンリポソームによる骨形成の促進2010

    • Author(s)
      馬紅梅、武洲、李銀姫、久木田敏夫、中西博
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミクログリアの産生するカテプシンBの炎症性疼痛発症における役割2010

    • Author(s)
      孫麗、武洲、中西博
    • Organizer
      第15回グリア研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Preferential inhibitory effects of S-ketamine on both NMDA receptor currents and neuropathic pain.2010

    • Author(s)
      Kawaji K, Hayshi Y, Koyano K, Yokoyama T, Nakanishi H
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Protective effects of microglia-conditioned medium against NMDA-induced dendritic injury through an inhibition of non-selective cation conductance.2010

    • Author(s)
      Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミクログリアのリソソーム・ミトコンドリア系を標的としたグリア創薬に可能性2010

    • Author(s)
      中西博
    • Organizer
      第130回日本薬学会年会、130回年会祈念融合型シンポジウム「グリア創薬の最前線と可能性」
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Reverse of the rheumatoid arthritis-induced acceleration of brain aging in the middle age by minocycline.2010

    • Author(s)
      Wu, Liu X, Nakanishi H
    • Organizer
      The 1st International Congress on Controversies in Longevity, Health and Aging
    • Place of Presentation
      Barcelona
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 中年ルイスラットにおけるアジュバント関節炎に伴うミクログリア活性化と海馬長期増強の障害2010

    • Author(s)
      武洲、劉霞、中西博
    • Organizer
      第63回日本薬理学会西南部会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Differebtial inolvement of astrocytes and microglia in neuronal survival after hypoglossal nerve injury.2010

    • Author(s)
      Yamada J, Jinno S, Nakanishi H
    • Organizer
      The 29^<th> Naito Conference : Glia World.
    • Place of Presentation
      湘南村
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] ミクログリアの産生するカテプシンBの炎症性疼痛発症における役割2010

    • Author(s)
      孫麗、武洲、中西博
    • Organizer
      第15回グリア研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Neuroprotection of microglia-conditioned medium on excitotoxic neuronal injury through inhibition of large cation conductance.2010

    • Author(s)
      Hayashi Y, Fujita S, Odagaki Y, Shinagawa R, Kagamiishi Y, Nakanishi H
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Microglial cathepsin B :A strategic target for neuroprotective agents.2010

    • Author(s)
      武洲, 中西博
    • Organizer
      BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010.
    • Place of Presentation
      上海
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Preferential inhibitory effects of S-ketamine on neuropatic pain through both the neuronal based and microglia related mechanisms.2010

    • Author(s)
      林良憲, 河路広大, 中西博
    • Organizer
      The 29^<th> Naito Conference : Glia World.
    • Place of Presentation
      湘南村
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Differebtial inolvement of astrocytes and microglia in neuronal survival after hypoglossal nerve injury.2010

    • Author(s)
      Yamada J, Jinno S, Nakanishi H
    • Organizer
      The 29^<th> Naito Conference : Glia World.
    • Place of Presentation
      湘南村
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミクログリアの産生するカテプシンS の神経障害性疼痛発症における役割2010

    • Author(s)
      張馨文、林良憲、武洲、中西博
    • Organizer
      第15回グリア研究会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Microglial cathepsin B : A strategic target for neuroprotective agents.2010

    • Author(s)
      武洲, 中西博
    • Organizer
      BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010.
    • Place of Presentation
      上海
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] A possible involvement of cathepsin B in nociceptive processing through the processing and secretion of interleukin-1 family from microglia.2010

    • Author(s)
      孫麗, 武洲, 林良憲, 中西博
    • Organizer
      Neuroscience 2010
    • Place of Presentation
      サンジエゴ
    • Year and Date
      2010-11-14
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Microglial cathepsin B : a strategic target for neuroprotective agents.2010

    • Author(s)
      Wu Z, Nakanishi H
    • Organizer
      BIT's Inaugural Symposium on Enzyme & Biocatalysis-2010
    • Place of Presentation
      Shanghai
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Microglia-aging : Roles of microglial lysosome-and mitochondria-derived reactive oxygen species in brain aging.2009

    • Author(s)
      中西博
    • Organizer
      第52回日本神経化学会、シンポジウム「ミクログリアの機能と病態-最近の研究動向と将来の展望-」
    • Place of Presentation
      群馬県伊香保
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 末梢炎症によるミクログリア活性化と脳老化の促進2009

    • Author(s)
      武洲、劉霞、中西博
    • Organizer
      第14回グリア研究会
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Age-dependent differential microglial and astrocytic responses through leptomeninges during systemic inflammation.2009

    • Author(s)
      武洲, 徳田幸恵, 張馨文, 中西博
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Microglia-aging : Roles of microglial lysosome-and mitochondria-derived reactive oxygen species in brain aging.2009

    • Author(s)
      中西博
    • Organizer
      第52回日本神経化学会、シンポジウム「ミクログリアの機能と病態-最近の研究動向と将来の展望-」
    • Place of Presentation
      群馬県伊香保
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Extracellular nucleotide-mediated reduced synaptic activityprecedes microglial synaptic stripping after an axotomy.2009

    • Author(s)
      中西博, 山田純
    • Organizer
      International Symposium on Purinergic Signalling in New Strategy of Drig Discovery, Fukuoka Purine 2009
    • Place of Presentation
      福岡
    • Year and Date
      2009-07-24
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 末梢炎症により惹起される脳炎症の老化による増悪-鍵を握る免疫担当細胞ミクログリアの動態について-2009

    • Author(s)
      中西博
    • Organizer
      第52回秋期日本歯周病学術大会シンポジウム
    • Place of Presentation
      宮崎
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Extracellular nucleotide-mediated reduced synaptic activity precedes microglial synaptic stripping after axotomy2009

    • Author(s)
      Nakanishi H.
    • Organizer
      Fukuoka Purine
    • Place of Presentation
      福岡
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] インターロイキン-1βのp38MAPキナーゼの活性化を介したNMDAにより惹起されるCa^<2+>活性化K^+電流の抑制作用2009

    • Author(s)
      Zhang R,劉霞、孫麗、林良憲、武洲、中西博
    • Organizer
      第62回日本薬理学会西南部会
    • Place of Presentation
      愛媛
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2009

    • Author(s)
      Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 末梢炎症により惹起される脳炎症の老化による増悪:鍵を握る脳の免疫担当細胞ミクリグリアの動態について2009

    • Author(s)
      中西博
    • Organizer
      第52回秋期日本歯周病学術大会、シンポジウム「歯周組織の免疫応答から考える全身への影響」
    • Place of Presentation
      宮崎
    • Year and Date
      2009-10-11
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 運動神経軸索切断後のアストロサイト形態・ミクログリアの形態の比較検討2009

    • Author(s)
      山田純、神野尚三、中西博
    • Organizer
      第14回グリア研究会
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] ミクログリアのニューロン保護作用:NMDA誘発こうフィン毒性に対するミクログリア培養上清の保護メカニズムの解析2009

    • Author(s)
      林良憲、中西博
    • Organizer
      第62回日本薬理学会西南部会
    • Place of Presentation
      愛媛
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 末梢炎症により惹起される脳炎症の老化による増悪:鍵を握る脳の免疫担当細胞ミクリグリアの動態について2009

    • Author(s)
      中西博
    • Organizer
      第52回秋期日本歯周病学術大会、シンポジウム「歯周組織の免疫応答から考える全身への影響」
    • Place of Presentation
      宮崎
    • Year and Date
      2009-10-11
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミクログリアのニューロン保護作用:NMDA誘発こうフィン毒性に対するミクログリア培養上清の保護メカニズムの解析2009

    • Author(s)
      林良憲、中西博
    • Organizer
      第62回日本薬理学会西南部会
    • Place of Presentation
      愛媛
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Microglia-aging : Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging2009

    • Author(s)
      中西博
    • Organizer
      第52回日本神経化学大会シンポジウム
    • Place of Presentation
      群馬県伊香保
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Age-dependent differential phenotypic changes of glial cells by systemic inflammation.2009

    • Author(s)
      武洲, 中西博
    • Organizer
      9^<th> European Meeting on Glial Cells in Health and Disease.
    • Place of Presentation
      パリ
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Age-dependent differential microglial and astrocytic responses through leptomeninges during systemic inflammation.2009

    • Author(s)
      Wu Z, Tokuda Y, Zhang XW, Nakanishi H
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Age-dependent differential phenotypic changes of glial cells by systemic inflammation.2009

    • Author(s)
      武洲, 中西博
    • Organizer
      9^<th> European Meeting on Glial Cells in Health and Disease.
    • Place of Presentation
      パリ
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Extracellular nucleotide-mediated reduced synaptic activity precedes microglial synaptic stripping after an axotomy. International Symposium on Purinergic Signalling in New Strategy of Drig Discovery2009

    • Author(s)
      中西博, 山田純
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      福岡
    • Year and Date
      2009-07-24
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Microglia-aging : Roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging2009

    • Author(s)
      Nakanishi H.
    • Organizer
      第52回日本神経化学大会シンポジウム
    • Place of Presentation
      群馬県伊香保
    • Year and Date
      2009-06-24
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Extracellular nucleotide-mediated reduced synaptic activity precedes microglial synaptic stripping after axotomy2009

    • Author(s)
      中西博
    • Organizer
      Fukuoka Purine
    • Place of Presentation
      福岡
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 末梢炎症により惹起される脳炎症の老化による増悪-鍵を握る免疫担当細胞ミクログリアの動態について-2009

    • Author(s)
      中西博
    • Organizer
      第52回秋期日本歯周病学術大会シンポジウム
    • Place of Presentation
      宮崎
    • Year and Date
      2009-10-10
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 運動神経軸索切断後のアストロサイト形態・ミクログリアの形態の比較検討2009

    • Author(s)
      山田純、神野尚三、中西博
    • Organizer
      第14回グリア研究会
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microgli2009

    • Author(s)
      Nakanishi H., et al
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-17
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2009

    • Author(s)
      Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] インターロイキン-1βのp38MAPキナーゼの活性化を介したNMDAにより惹起されるCa^<2+>活性化K^+電流の抑制作用2009

    • Author(s)
      Zhang R, 劉霞、孫麗、林良憲、武洲、中西博
    • Organizer
      第62回日本薬理学会西南部会
    • Place of Presentation
      愛媛
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2009

    • Author(s)
      Nakanishi H., et al.
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-17
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] 末梢炎症によるミクログリア活性化と脳老化の促進2009

    • Author(s)
      武洲、劉霞、中西博
    • Organizer
      第14回グリア研究会
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2008

    • Author(s)
      Nakanishi H., et al.
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミトコンドリア転写因子Aの過剰発現によるミトコンドリア内レドックス制御ならびに老化に伴う脳機能低下の制御2008

    • Author(s)
      中西博、林良憲、井手友美、武洲
    • Organizer
      第61回日本薬理学会西南部会
    • Place of Presentation
      米子
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Phospathidylserine-containing liposomes ameliorates the cytokine imbalance in the ankle joints of adjuvant arthritic rats.2008

    • Author(s)
      馬紅梅、武洲、中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 末梢炎症に対する髄膜-グリア連関の反応の老化に伴う変容2008

    • Author(s)
      武洲, 中西博
    • Organizer
      第61回日本西南部会
    • Place of Presentation
      米子
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Age-dependent differentiatial regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008

    • Author(s)
      武洲, 中西博
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] ミトコンドリア転写因子Aの過剰発現によるミクログリア内レドックス制御ならびに老化に伴う脳機能低下の抑制2008

    • Author(s)
      中西 博, 他
    • Organizer
      第61回日本西南部会
    • Place of Presentation
      米子
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2008

    • Author(s)
      Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2008

    • Author(s)
      Nakanishi H., et al.
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 中高年における慢性末梢炎症は深刻な脳炎症を引き起こす2008

    • Author(s)
      徳田幸恵、張馨文、武洲、中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Phospathidylserine-containing liposomes ameliorates the cytokine imbalance in the ankle joints of adjuvant arthritic rats.2008

    • Author(s)
      馬紅梅、武洲、中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008

    • Author(s)
      張馨文, 武洲, 中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of extracellular nucleotides in microglial synaptic strippingresponse.2008

    • Author(s)
      中西博
    • Organizer
      第81回日本薬理学会年会、シンポジウム「細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与」
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] TFAM過剰発現によるミクログリア内レドックス制御と老化に伴う脳機能低下の防止2008

    • Author(s)
      林良憲、井手友美、中西博
    • Organizer
      第13回グリア研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008

    • Author(s)
      中西 博
    • Organizer
      第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御一分子ダイナミクスと疾病への関与
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Age-dependent differential regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008

    • Author(s)
      Wu Z., Nakanishi H.
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Age-dependent differentiation of the barrier function of the leptomeninges in the cerebral cortex by activated glial cells during the systemic inflammation.2008

    • Author(s)
      武洲, 徳田幸恵, 張馨文, 中西博
    • Organizer
      第26回CINP
    • Place of Presentation
      ミュンヘン
    • Year and Date
      2008-07-13
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Reduced synaptic activity mediated by extracellular nucleotides precedes synaptic stripping after an axotomy.2008

    • Author(s)
      Yamada J, Jinno S, Nakanishi H
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Synaptic Stripping における細胞外ヌクレオチドの関与2008

    • Author(s)
      中西 博
    • Organizer
      第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Overexpression of human TFAM prevents age-dependent memory impairement in mice by suppression of mitochondrial oxidative stress.2008

    • Author(s)
      Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Nakanishi H
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008

    • Author(s)
      中西 博
    • Organizer
      第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Reduced synaptic activity mediated by extracellular nucleotides precedes synaptic stripping after an axotomy.2008

    • Author(s)
      Yamada J, Jinno S, Nakanishi H
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Novel therapeutuc intervention with overexpression of TFAM against the age-dependent memory impairement.2008

    • Author(s)
      Hayshi Y, Yoshida M, Yamamto M, Ide T, Kang D, Nakanishi H
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] TFAM過剰発現によるミクログリア内レドックス制御と老化に伴う脳機能低下の防止2008

    • Author(s)
      林良憲、井手友美、中西博
    • Organizer
      第13回グリア研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Age-dependent differentiatial regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008

    • Author(s)
      武洲, 中西博
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Involvement of cathepsin Bin the processing and secretion of interleukin-1β inchromogranin A-stimulated microglia2008

    • Author(s)
      Nakanishi H., et al
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントン DC
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Age-dependent differentiation of the barrier function of the leptomeninges in the cerebral cortex by activated glial cells during the systemic inflammation.2008

    • Author(s)
      Wu Z, Tokuda Y, Zhang XW, Nakanishi H
    • Organizer
      第26回CINP
    • Place of Presentation
      ミュンヘン
    • Year and Date
      2008-07-13
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008

    • Author(s)
      中西 博
    • Organizer
      第81回日本薬理学会総会、シンポジウム=細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Synaptic Stripping における細胞外ヌクレオチドの関与2008

    • Author(s)
      中西 博
    • Organizer
      第81回日本薬理学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] 破骨前駆細胞の貪食機能に着目した新たな骨破壊抑制法2008

    • Author(s)
      武洲、馬紅梅、中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of extracellular nucleotides in microglial synaptic stripping response.2008

    • Author(s)
      中西博
    • Organizer
      第81回日本薬理学会年会、シンポジウム「細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与」
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 破骨前駆細胞の貪食機能に着目した新たな骨破壊抑制法2008

    • Author(s)
      武洲、馬紅梅、中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] ミトコンドリア転写因子Aの過剰発現によるミトコンドリア内レドックス制御ならびに老化に伴う脳機能低下の制御2008

    • Author(s)
      中西博、林良憲、井手友美、武洲
    • Organizer
      第61回日本薬理学会西南部会
    • Place of Presentation
      米子
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 末梢炎症に対する髄膜-グリア連関の汎脳性の老化に伴う変容2008

    • Author(s)
      武洲、中西博
    • Organizer
      第61回日本薬理学会西南部会
    • Place of Presentation
      米子
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of p38 MAPK in interleukin-1b-induced inhibition of NMDA-induced outward currents in hippocampal neurons2008

    • Author(s)
      Zhang R., Nakanishi H.
    • Organizer
      Berlin Brain Days 2008
    • Place of Presentation
      ベルリン
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons.2008

    • Author(s)
      Zhang R, Wu Z, Nakanishi H
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] 細胞内標識法を用いたミクログリアならびにアストロサイト突起の微細構造の解析2008

    • Author(s)
      山田純、神野尚三、中西博
    • Organizer
      第13回グリア研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia2008

    • Author(s)
      Nakanishi H., et al.
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] 末梢炎症に対する髄膜-グリア連関の汎脳性の老化に伴う変容2008

    • Author(s)
      武洲、中西博
    • Organizer
      第61回日本薬理学会西南部会
    • Place of Presentation
      米子
    • Year and Date
      2008-11-28
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Age-dependent differential regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008

    • Author(s)
      Wu Z., Nakanishi H.
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] 細胞内標識法を用いたミクログリアならびにアストロサイト突起の微細構造の解析2008

    • Author(s)
      山田純、神野尚三、中西博
    • Organizer
      第13回グリア研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-08
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia.2008

    • Author(s)
      Nakanishi H, Terada K, Yamada J, Hayashi Y, Wu Z
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Overexpression of human TFAM prevents age-dependent memory impairement in mice by suppression of mitochondrial oxidative stress.2008

    • Author(s)
      Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Nakanishi H
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-23
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] 中高年における慢性末梢炎症は深刻な脳炎症を引き起こす2008

    • Author(s)
      徳田幸恵、張馨文、武洲、中西博
    • Organizer
      第50基礎歯科医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Age-dependent differential regulation of tight junction proteins in the leptomeninges by glial cells during systemic inflammation.2008

    • Author(s)
      Wu Z., Nakanishi H.
    • Organizer
      米国神経科学会議
    • Place of Presentation
      ワシントンDC
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-20390472
  • [Presentation] Novel therapeutuc intervention with overexpression of TFAM against the age-dependent memory impairement.2008

    • Author(s)
      Hayshi Y, Yoshida M, Yamamto M, Ide T, Kang D, Nakanishi H
    • Organizer
      第81回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-20592174
  • [Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2008

    • Author(s)
      中西 博
    • Organizer
      第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御-分子ダイナミクスと疾病への関与
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007

    • Author(s)
      Nakanishi H., Wu Z., and Ochi-Shindou M
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Systemic inflammation induces age-dependent defferential activation of glial cells through the leptomeninges.2007

    • Author(s)
      Wu, Z., Nakanishi, H
    • Organizer
      8 th Euroglia Meeting
    • Year and Date
      2007-09-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Systemic inflammation induces age-dependent defferential activation ofglial cells through the leptomeninges2007

    • Author(s)
      Wu Z. and Nakanishi H.
    • Organizer
      第8回ヨーロッパグリア(Eurogha)会議
    • Place of Presentation
      ロンドン
    • Year and Date
      2007-09-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007

    • Author(s)
      Nakanishi, H., Wu, H., Ochi-Shindou, M
    • Organizer
      37th Society for Neuroscience Meeting
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Systemic inflammation induces age-dependent differential activation of glial cells through the leptomeninges.2007

    • Author(s)
      Wu Z. and Nakanishi H.
    • Organizer
      第8回ヨーロッパグリア(Euroglia)会議
    • Place of Presentation
      ロンドン
    • Year and Date
      2007-09-06
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Modulation of NMDA receptor-mediated responses by microglial secretingsoluble factors2007

    • Author(s)
      Hayashi Y. and Nakanishi H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Induction of age-related differential cytokine responses in the brain through microglia by systemic inflammation2007

    • Author(s)
      Wu Z.and Nakanishi H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Systemic inflammation induces age-dependent defferential activation of gilal cell sthrough the leptomeninges.2007

    • Author(s)
      Wu, Z・Nakanishi, H.
    • Organizer
      第8回ヨーロッパグリア(Euroglia) 会議
    • Place of Presentation
      ロンドン
    • Year and Date
      2007-09-06
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Presentation] Systemic inflammation induces age-dependent defferential activation of glial cells through the leptomeninges.2007

    • Author(s)
      Wu Z.and Nakanishi H.
    • Organizer
      第8回ヨーロッパグリア(Euroglia)会議
    • Place of Presentation
      ロンドン
    • Year and Date
      2007-09-06
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Synaptic Strippingにおける細胞外ヌクレオチドの関与2007

    • Author(s)
      中西 博
    • Organizer
      Synaptic Strippingにおける細胞外ヌクレオチドの関与学会 等名第81回日本薬理学会総会、シンポジウム:細胞外ヌクレオチドによる脳機能制御一分子ダイナミクスと疾病への関与
    • Place of Presentation
      横浜
    • Year and Date
      2007-03-17
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Systemic inflammation induces age-dependent defferential activation ofglial cells through the leptomeninges2007

    • Author(s)
      Wu Z., Nakanishi H.
    • Organizer
      第8回ヨーロッパグリア(Euroglia)会議
    • Place of Presentation
      ロンドン
    • Year and Date
      2007-09-06
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice.2007

    • Author(s)
      Nakanishi H., Wu Z., and Ochi-Shindou M.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Induction of age-related differential cytokine responses in the brain throughmicroglia by systemic inflammation2007

    • Author(s)
      Wu Z., Nakanishi H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Induction of age-related differential cytokine responses in the brain through microglia by systemic inflammation2007

    • Author(s)
      Wu, Z., Nakanishi, H
    • Organizer
      37 th Society for Neuroscience Meeting
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Modulation of NMDA receptor-mediated responses by microglial secreting soluble factors.2007

    • Author(s)
      Hayashi Y.and Nakanishi H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-07
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Modulation of NMDA receptor-mediated responses bymicroglial secreting soluble factors.2007

    • Author(s)
      Hayashi, Y., Nakanishi, H
    • Organizer
      37 th Society for Neuroscience Meeting
    • Year and Date
      2007-11-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007

    • Author(s)
      Nakanishi H., Wu Z., and Ochi-Shindou M
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Systemic inflammation induces age- dependent defferential activation of glial cells through the leptomeninges2007

    • Author(s)
      Wu, Z., Nakanishi, H
    • Organizer
      18th Euroglia Meeting
    • Year and Date
      2007-09-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Systemic inflammation induces age-dependent defferential activation of glial cells through the leptomeninges2007

    • Author(s)
      Wu Z.and Nakanishi H.
    • Organizer
      第8回ヨーロッパグリア(Euroglia)会議
    • Place of Presentation
      ロンドン
    • Year and Date
      2007-09-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Modulation of NMDA receptor-mediated responses by microglial secreting soluble factors2007

    • Author(s)
      Hayashi Y.and Nakanishi H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice2007

    • Author(s)
      Nakanishi H., et al
    • Organizer
      米国神経科学会議
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-19592171
  • [Presentation] Induction of age-related differential cytokine responses in the brain through microglia by systemic inflammation.2007

    • Author(s)
      Wu, Z., Nakanishi, H
    • Organizer
      37 th Society for Neuroscience Meeting
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Modulaton of NMDA receptor-mediated responses by microglial secreting soluble factors.2007

    • Author(s)
      Hayashi, Y・Nakanishi, H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-07
    • Data Source
      KAKENHI-PROJECT-15082204
  • [Presentation] Modulation of NMDA receptor-mediated responses bymicroglial secreting soluble factors2007

    • Author(s)
      Hayashi, Y., Nakanishi, H
    • Organizer
      37 th Society for Neuroscience Meeting
    • Year and Date
      2007-11-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Induction of age-related differential cytokine responses in thebrain through microglia by systemic inflammation2007

    • Author(s)
      Wu Z. and Nakanishi H.
    • Organizer
      第37回北米神経科学会
    • Place of Presentation
      サンディエゴ
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] Overproduction of nitric oxide by microglia due to lysosomal storage-induced p38 MAP kinase activation in cathepsin D-deficient mice.2007

    • Author(s)
      Nakanishi, H., Wu, Z., Ochi-Shindou, M
    • Organizer
      37 th Society for Neuroscience Meeting
    • Year and Date
      2007-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats.2006

    • Author(s)
      Hayashi, Y., Suzuki, H., Sawada, M., Nakanishi, H
    • Organizer
      36 th Society for Neuroscience Meeting
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-10-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] ミクログリアによる神経保護機構:闇と光のスイッチング機構2006

    • Author(s)
      中西 博
    • Organizer
      第18回日本神経免疫学会、シンポジウム「免疫学的機序による神経細胞傷害」
    • Place of Presentation
      名古屋
    • Year and Date
      2006-03-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18613010
  • [Presentation] The intra- arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats2006

    • Author(s)
      Hayashi, Y., Suzuki, H., Sawada, M., Nakanishi, H
    • Organizer
      36th Society for Neuroscience Meeting
    • Place of Presentation
      Atlanta
    • Year and Date
      2006-10-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] ミクログリアによる神経保護機構:闇と光のスイッチング機構2006

    • Author(s)
      中西 博
    • Organizer
      第18回日本神経免疫学会、シンポジウム「免疫学的機序による神経細胞傷害」
    • Place of Presentation
      名古屋
    • Year and Date
      2006-03-02
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] Deficiency of lysosomal proteases and disorderdes neuronal and microglial functions2005

    • Author(s)
      中西 博
    • Organizer
      第48回日本神経化学会、理事会企画公開シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2005-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] ミクログリアのマクロファージ様機能と脳特異的機能2005

    • Author(s)
      中西 博
    • Organizer
      第17回日本神経免疫学会、モーニングセミナー
    • Place of Presentation
      福岡
    • Year and Date
      2005-03-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390495
  • [Presentation] 歯周病菌による脳髄膜を介したミクログリアの活性化

    • Author(s)
      武 洲、中西 博
    • Organizer
      第56回歯科基礎医学会学術大会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻

    • Author(s)
      岡田 亮、武 洲、倪 軍軍、中西 博
    • Organizer
      第18回グリア研究会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] クロモグラニンA(CGA)によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明

    • Author(s)
      武 洲、中西 博
    • Organizer
      第55回歯科基礎医学学術大会
    • Place of Presentation
      岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割

    • Author(s)
      張 馨文、武 洲、林 良憲、中西 博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] クロモグラニンA(CGA)によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明

    • Author(s)
      武 洲、中西 博
    • Organizer
      第55回歯科基礎医学学術大会
    • Place of Presentation
      岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] 神経障害性トプ痛の慢性化におけるカテプシンSの役割

    • Author(s)
      張 馨文、武 洲、林 良憲、中西 博
    • Organizer
      第66回日本薬理学会西南部会
    • Place of Presentation
      福岡大学
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] クロモグラニンA(CGA)によるミクログリアにおけるカテプシンBに依存した新規産生経路の解明

    • Author(s)
      武 洲、中西 博
    • Organizer
      第55回歯科基礎医学学術大会
    • Place of Presentation
      岡山コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] A big channel in small glia as a promising molecular target for the treatment of opioid-induced hyperalgesia

    • Author(s)
      林 良憲、中西 博
    • Organizer
      第120回日本解剖学会総会・第92回日本生理学会大会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2015-03-21 – 2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] ミクログリアのカテプシンS発現リズムによるシナプス強度の調節機構の解明

    • Author(s)
      林 良憲、小柳 悟、楠瀬直樹、岡田 亮、武 洲、斉藤秀俊、大戸茂弘、高坂新一、井上和秀、中西 博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] 歯周病菌による脳髄膜を介したミクログリアの活性化

    • Author(s)
      武 洲、中西 博
    • Organizer
      第56回歯科基礎医学会学術大会 サテライトシンポジウム
    • Place of Presentation
      福岡国際センター
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割

    • Author(s)
      張 馨文、武 洲、林 良憲、中西 博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] Microglial circadian clock controls diurnal changes in synaptic strength through microglia-synaptic interactions

    • Author(s)
      中西 博
    • Organizer
      Neuro2013
    • Place of Presentation
      国立京都国際会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] Batten病モデルマウスにおける脳ペリサイトの酸化ストレス障害と血液脳関門の破綻

    • Author(s)
      岡田 亮、武 洲、倪 軍軍、中西 博
    • Organizer
      第18回グリア研究会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] 2種類のミクログリア突起の日内変化に関する形態学的ならびに生体イメージング解析

    • Author(s)
      高山 扶美子 林 良憲、武 洲、中西 博
    • Organizer
      第56回歯科基礎医学会学術大会
    • Place of Presentation
      福岡国際センター
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] Novel roles of microglia

    • Author(s)
      中西 博
    • Organizer
      第1回 MS Summer College
    • Place of Presentation
      電気ビル みらいホール&カンファレンス(福岡)
    • Year and Date
      2014-08-02 – 2014-08-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390416
  • [Presentation] The possible link between periodontitis and Alzheimer's disease

    • Author(s)
      武 洲、中西 博
    • Organizer
      中国薬理学会・老年医学会・認知機能障害と関連疾患シンポジウム
    • Place of Presentation
      中国 青海省西寧市
    • Year and Date
      2014-08-09 – 2014-08-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-24592802
  • [Presentation] Batten病モデルマウスにおける脳ペリサイトの消失と血液脳関門の破綻、第66回日本薬理学会西南部会

    • Author(s)
      岡田 亮、武 洲、倪 軍軍、中西 博
    • Organizer
      第66回日本薬理学会西南部会
    • Place of Presentation
      福岡大学
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割

    • Author(s)
      張 馨文、武 洲、林 良憲、中西 博
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] Microglial circadian clock controls diurnal changes in synaptic strength through microglia-synaptic interactions

    • Author(s)
      中西 博
    • Organizer
      Neuro2013
    • Place of Presentation
      国立京都国際会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659827
  • [Presentation] 歯周病菌によるアルツハイマー様脳病態の促進メカニズム

    • Author(s)
      武 洲、中西 博
    • Organizer
      第88回日本薬理学学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390416
  • 1.  YAMAMOTO Kenji (40091326)
    # of Collaborated Projects: 19 results
    # of Collaborated Products: 0 results
  • 2.  TAKE Hiro (10420598)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 117 results
  • 3.  TSUKUBA Takayuki (30264055)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  AKAMINE Akifumi (00117053)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  坂井 英昭 (40225769)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MONJI Akira (00294942)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  HAYASHI Yoshinori (80582717)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 8.  IWATA Koichi (60160115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SHINODA Masamichi (20362238)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  HORI Nobuaki (60037520)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  西村 英紀 (80208222)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  SHINDOU Mayumi (10444796)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  KOBAYASHI Masayuki (00300830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  AOKI Yosuke (80049030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IKAI Atsushi (50011713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KATO Ihachi (30005087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KUNIMATSU Kazushi (20170011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  YOSHIMINE Yoshito (80183705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MAEDA Hidefumi (10284514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  Yamashita Akiko (70511319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  筑波 知子 (70336080)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  岡元 邦彰 (10311846)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  田中 嘉孝 (20217095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  岩下 未咲 (80611326)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  倪 軍軍 (00783953)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 23 results
  • 26.  野中 さおり (40767787)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 27.  小田 康祐 (60571255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  坂口 剛正 (70196070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  TAKAYAMA Fumiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 30.  金井 貞
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  浅尾 哲次
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  TETSUJI Asao
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  浅尾 哲治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SATOH Yasushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  SAITOH Hidetoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  高橋 寿明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  羽鳥 勇太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  井上 和秀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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