Furukawa Kenichi 古川賢一

… Alternative Names

FURUKAWA Ken-Ichi 古川賢一

FURUKAWA Kenichi 古川賢一

FURUKAWA Ken-ichi 古川賢一

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Researcher Number	20165468
Other IDs
External Links
Affiliation (Current)	2025: 弘前大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2019: 弘前大学, 医学研究科, 客員研究員 2016 – 2018: 弘前大学, 医学研究科, 准教授 2015: 弘前大学, 大学院医学研究科, 准教授 2012 – 2015: 弘前大学, 医学(系)研究科(研究院), 准教授 2008 – 2010: Hirosaki University, 大学院・医学研究科, 准教授 … More 2004 – 2005: 弘前大学, 医学部, 助教授 2000 – 2002: 弘前大学, 医学部, 助教授 1997: 弘前大学, 医学部, 助教授 1991 – 1997: 東北大学, 薬学部, 助手 1994: 東北大学, 助手 1989: National Cardiovasc. Ctr, Dept.of molec. physiol, Research associate, 循環分子生理部, 室員 1988: 国立循環器病センター, 研究所・循環分子生理部, 室員 Less
Review Section/Research Field	Principal Investigator General pharmacology / Orthopaedic surgery / General pharmacology / Functional biochemistry Except Principal Investigator Biological pharmacy / Orthopaedic surgery / Cardiovascular surgery / General surgery / Circulatory organs internal medicine / Anesthesiology/Resuscitation studies / General physiology
Keywords	Principal Investigator 異所性骨化 / メカニカルストレス / 形質転換 / 内軟骨性骨化 / Cbfa1 / siRNA / 天然生理活性物質 / 脊柱靭帯骨化症 / エピジェネティクス / 脊柱靭帯 … More / 間葉系幹細胞 / 薬物治療 / Ca遊離 / 治療薬 / コンドロモジュリン / CXCR4 / SDF-1 / 細胞遊走 / 骨化抑制 / スクリーニング / 生理活性物質 / DNAメチル化 / endochondral ossification / nucleotide receptor / gene expression / microarray / mechanical stress / ectopic bone formation / ヌクレオチド受容体 / 遺伝子発現 / マイクロアレイ / bioactive natural products / calcium release / muscle contraction / intracellular calcium / L6細胞 / 機械的刺激 / リアノジン受容体 / カルシウム遊離 / 筋収縮 / 細胞内カルシウムイオン / セルソーティング / 多分化能 / 骨分化能 / ニッチ / ATP / 遺伝子導入 / 細胞外ヌクレオチド受容体 / アルカリフォスファターゼ / TSG-6 / 骨化様式 / 過剰発現 / P2Y1 / BMP2 / gremlin / 幹細胞 / 細胞外ATP受容体 / 脊柱靱帯骨化症 / 機械的ストレス / 脊柱靱帯 / Ca遊離チャネル / トライアジン / 骨格筋 / カルセクエストリン / マイオトキシンa / リアノジンレセプター … More Except Principal Investigator カルシウム / 血管平滑筋 / ゴニオドミンA / アクチン / トキシン / カフェイン / チャンネル / ハレナキノン / チャネル / 海洋微生物 / マトリックスGlaタンパク質 / 大動脈弁間質細胞 / 大動脈弁狭窄症 / RNA / DNA / ATPase / Ca^<2+> / Ca / トロンボキサンA_2 / 血小板 / ニトロプルシド / 心房性利尿ペプチド / フォルボールエステル / プロテインキナーゼ / 細胞内Caイオン濃度 / 環状ヌクレオチド / 細胞膜CaATPポンプ / 遺伝子 / calcium / MAPキナーゼ / ズ-ザンテラトキシンA / アポトーシス / 海洋微細藻 / ユ-ジストミン / 細胞運動 / 細胞毒性 / 中枢神経 / モノクローナル抗体 / 蛋白質精製 / 膜電位 / Cキナ-ゼ / 細胞膜Caポンプ / 細胞移植 / 機能回復 / Muse細胞 / 脊髄損傷 / 臨床 / CD34細胞 / ビタミンK依存性蛋白 / BMP2 / 薬物送達 / 大動脈弁石灰化 / 分子標的薬 / 石灰化大動脈弁 / 大動脈弁狭窄 / 薬理学 / 外科 / テネイシンX / 異所性石灰化 / cyclic nucleotide / membrane potential / protein kinase C / Ca^<2+> pump / Vascular Smooth Muscle / プロテインキナ-ゼ / 環状ヌクレオチッド / gene / Microarray / sleep / Anesthesia / マイクロアレイ / 睡眠 / 麻酔 / thromboxane A_2 / platelete aggregation / muscle cells / plateles / marine products / 筋収縮 / IIb-IIIa / 蛋白リン酸化 / 形態変化 / BKチャネル / Ca^<2+>遊離チャネル / 9-methyl-7-bromoeudistomin D / 血小板凝集 / 筋細胞 / 海洋天然物 / Evodiamine / Ca pump / Myosin / Xestquinone / Gingerol / Ca^<2+>ATPアーゼ / 強心薬 / エボジアミン / カルシウムポンプ / ミオシン / ジンゲロール / セストキノン / Eudistomin / Zooxanthellatoxin-A / Maitotoxin / Astrocytoma / Platelet / Marine toxine / Channel / K-ATPase / Na / ホスホリパーゼC / ズ-サンテラトキシンA / メチルベッド / ホスホリパーゼA_2 / ズ-ザンテラトキシン-A / マイトトキシン / アストロサイトーマ / マリントキシン / phosphorylation / ECG / マウス / sympathetic nerve / mouse / channel / 筋小胞体 / カルシウム遊離 / マイオトキシンa / リアノジンレセプター / カルセクエストリン / トライアジン / P13キナーゼ / 血管新生阻害 / G蛋白 / rho / Ca動態 / PI-3-Kinase / Ca遊離 / キノリドマイシン / パラグアイ産生薬 / 脳 / 平滑筋 / 骨格筋 / ブロモユ-ジストミンD / リアノジン / カルシウム遊離チャンネル / ユージストミン / ジアシルグリセロール / タンパク精製 Less

Elucidation of the mechanism of mesenchymal stem cell abnormality causing ossification of spinal ligament and target search of therapeutic agents based on the mechanismPrincipal Investigator
- Principal Investigator
  
  Furukawa Kenichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hirosaki University
Transplantation of Multilineage-differentiating stress-enduring cells after spinal cord injury in mice
- Principal Investigator
  
  Kumagai Gentaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Hirosaki University
Calcific aortic stenosis: Identification of calcification-inducing cell, clarifying calcification signaling
- Principal Investigator
  
  Seya Kazuhiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hirosaki University
To investigate mechanism of aortic valve calcification and to establish medical agents for aortic valve stenosis
- Principal Investigator
  
  Daitoku Kazuyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Hirosaki University
Sympathetic nerve control with the voltage-dependent calcium channel beta subunits.
- Principal Investigator
  
  murakami manabu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Hirosaki University
Role of mesenchymal stem cells as a cause of ectopic ossification of spinal ligamentPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Ken-Ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hirosaki University
Exploring molecular targets for the establishment of drug therapy for the ossification of the posterior longitudinal ligament of the spinePrincipal Investigator
- Principal Investigator
  
  FURUKAWA Kenichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hirosaki University
Analysis of genes related to the ectopic bone formation induced by mechanical stress and search for drugs targeting the genes.Principal Investigator
- Principal Investigator
  
  FURUKAWA Ken-Ichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hirosaki University
Detection of sleep regulating genes by DNA microarray to apply for clinical anesthesia
- Principal Investigator
  
  TAKAHASHI Satoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Screening and characterization of new regulation factor of Ca^<2+> release channelsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Ken-ichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hirosaki University
新しい医薬資源からの抗腫瘍性成分の検索とその作用機序の解明
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
イオンチャネル機能探索分子の開発と情報伝達機構解明への応用
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
海洋生物および生薬に含まれる抗腫瘍成分の化学および生物学的研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
リアノジンレセプターカルシウム遊離チャンネルの分子調節機構の解析Principal Investigator
- Principal Investigator
  
  古川賢一
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Elucidation of the mechanism of excitatory action of marine natural products on platelets and muscle cells
- Principal Investigator
  
  OHIZUMI Yasushi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
海洋生物および生薬に含まれる抗腫瘍性成分の化学および生物学的研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
イオンチャネルとその活性調節物質による超分子形成
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
海洋生物に含まれる抗腫瘍性成分の化学および生物学的研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
海洋微生物に含まれる抗腫瘍性成分の化学および生物学的研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
強力なカフェイン感受性チャンネル開口薬MBEDを用いたCa遊離チャンネルの研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Pharmacological studies on toxins from marine organism
- Principal Investigator
  
  OHIZUMI Yasushi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOHOKU UNIVERSITY
Basic and applied studies on cardiotonic
- Principal Investigator
  
  OHIZUMI Yasushi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOHOKU UNIVERSITY
強力なカフェイン感受性チャンネル開口薬MBEDを用いたCa遊離チャンネルの研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
強力なカフェイン感受性チャンネル開口薬MBEDを用いたCa遊離チャンネルの研究
- Principal Investigator
  
  OHIZUMI Yasushi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
環状ヌクレオチッドによる血管平滑筋細胞Ca輸送系の作用調節機構の研究
- Principal Investigator
  
  SHIGEKAWA Munekazu
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
環状ヌクレオチドによる血管平滑筋細胞Ca輸送系の作用調節機構の研究
- Principal Investigator
  
  重川宗一
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cardiovascular Center Research Institute
Study on Regulation of Ca^<2+> transport systems in vasculas smooth muscle cells.
- Principal Investigator
  
  SHIGEKAWA Munekazu
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular center

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2004 Other

All Journal Article Presentation

[Journal Article] Neurotrophic Factor Secretion and Neural Differentiation Potential of Multilineage-differentiating Stress-enduring (Muse) Cells Derived from Mouse Adipose Tissue2019
- Author(s)
  Nitobe Yohshiro、Nagaoki Toshihide、Kumagai Gentaro、Sasaki Ayako、Liu Xizhe、Fujita Taku、Fukutoku Tatsuhiro、Wada Kanichiro、Tanaka Toshihiro、Kudo Hitoshi、Asari Toru、Furukawa Ken-Ichi、Ishibashi Yasuyuki
- Journal Title
  
  Cell Transplantation
  
  Volume: 28 Issue: 9-10 Pages: 1132-1139
- DOI
  10.1177/0963689719863809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10916, KAKENHI-PROJECT-17K10917
[Journal Article] Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor2019
- Author(s)
  Yu Zaiqiang、Seya Kazuhiko、Chiyoya Mari、Daitoku Kazuyuki、Motomura Shigeru、Imaizumi Tadaatsu、Fukuda Ikuo、Furukawa Ken-Ichi
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: in oress Issue: 6 Pages: 944-956
- DOI
  10.1007/s00774-019-01001-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10449, KAKENHI-PROJECT-19K09089, KAKENHI-PROJECT-18K16381, KAKENHI-PROJECT-16K10619, KAKENHI-PROJECT-17K10916
[Journal Article] Facilitation of Chemotaxis Activity of Mesenchymal Stem Cells via Stromal Cell?Derived Factor-1 and Its Receptor May Promote Ectopic Ossification of Human Spinal Ligaments2019
- Author(s)
  Chin Shunfu、Furukawa Ken-Ichi、Kurotaki Keigo、Nagasaki Shunpei、Wada Kanichiro、Kumagai Gentaro、Motomura Shigeru、Ishibashi Yasuyuki
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 369 Issue: 1 Pages: 1-8
- DOI
  10.1124/jpet.118.254367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10916
[Journal Article] Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves2018
- Author(s)
  Chiyoya M, Seya K, Yu Z, Daitoku K, Motomura S, Imaizumi T, Fukuda I, Furukawa KI
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 136 Pages: 257-265
- NAID
  130007812658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10619
[Journal Article] Poor motor-function recovery after spinal-cord injury in anxiety-model mice with phospholipase　related catalytically inactive protein type 1 knockout.2018
- Author(s)
  Taka Fujita, Gentaro Kumagai, Xizhe Liu, Kanichiro Wada, Toshihiro Tanaka, Hitoshi Kudo, Toru Asari, Tatsuhiro Fukutoku, Ayako Sasaki, Yohshiro Nitobe, Yoshikazu Nikaido, Ken-Ichi Furukawa, Masato Hirata, Takashi Kanematsu, Shinya Ueno, Yasuyuki Ishibash
- Journal Title
  
  Journal of Neurotrauma
  
  Volume: 印刷中 Issue: 12 Pages: 1379-1386
- DOI
  10.1089/neu.2017.5492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10917, KAKENHI-PROJECT-15H04889, KAKENHI-PROJECT-18K08846, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-16K11503
[Journal Article] 脊柱靭帯骨化症研究の進歩＿脊柱靭帯骨化を起こす間葉系幹細胞の異常2018
- Author(s)
  古川賢一、和田簡一郎、熊谷玄太郎、石橋恭之
- Journal Title
  
  臨床雑誌整形外科
  
  Volume: 69
- Data Source
  KAKENHI-PROJECT-17K10916
[Journal Article] Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves2018
- Author(s)
  Chiyoya Mari、Seya Kazuhiko、Yu Zaiqiang、Daitoku Kazuyuki、Motomura Shigeru、Imaizumi Tadaatsu、Fukuda Ikuo、Furukawa Ken-Ichi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 136 Issue: 4 Pages: 257-265
- DOI
  10.1016/j.jphs.2018.03.004
- NAID
  130007812658
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10449, KAKENHI-PROJECT-15K10231
[Journal Article] Suppression of osteogenic differentiation in mesenchymal stem cells from patients with ossification of the posterior longitudinal ligament by a histamine-2-receptor antagonist2017
- Author(s)
  Liu X, Kumagai G, Wada K, Tanaka T, Fujita T, Sasaki A, Furukawa KI
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 810 Pages: 156-162
- DOI
  10.1016/j.ejphar.2017.07.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10916
[Journal Article] Ketamine suppresses the proliferation of rat C6 glioma cells2017
- Author(s)
  Niwa Hidetomo、Furukawa Ken-Ichi、Seya Kazuhiko、Hirota Kazuyoshi
- Journal Title
  
  Oncology Lett.
  
  Volume: 14 Issue: 4 Pages: 4911-4917
- DOI
  10.3892/ol.2017.6806
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10449, KAKENHI-PROJECT-16K20078
[Journal Article] Simultaneous measurement of adenosine 3’,5’-cyclic monophosphate and guanosine 3’,5’-cyclic monophosphate in biological samples.2017
- Author(s)
  Kazuhiko Seya, Shigeru Motomura, Tadaatsu Imaizumi, Ken-Ichi Furukawa.
- Journal Title
  
  Hirosaki Med J
  
  Volume: 68 Pages: 52-61
- NAID
  130008036645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10449
[Journal Article] High Osteogenic Potential of Adipose- and Muscle-derived Mesenchymal Stem Cells in Spinal-Ossification Model Mice.2017
- Author(s)
  Liu X, Kumagai G, Wada K, Tanaka K, Asari T, Oishi K, Fujita T, Mizukami H, Furukawa KI
- Journal Title
  
  Spine
  
  Volume: 42 Issue: 23 Pages: E1342-E1349
- DOI
  10.1097/brs.0000000000002266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10916
[Journal Article] 1-Methyl-2-undecyl-4(1H)-quinidone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-12016
- Author(s)
  Kazuhiko Seya, Ken-Ichi Furukawa, Mari Chiyoya, Zaiqiang Yu, Haruhisa Kikuchi, Kazuyuki Daitoku, Shigeru Motomura, Manabu Murakami, Yoshiteru Oshima, and Ikuo Fukuda
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 131 Issue: 1 Pages: 51-57
- DOI
  10.1016/j.jphs.2016.04.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10449
[Journal Article] Decreased DNA methylation in the promoter region of the WNT5A and GDNF genes may promote the osteogenicity of mesenchymal stem cells from patients with ossified spinal ligaments.2015
- Author(s)
  Chiba N, Furukawa K-I, Takayama S, Asari T, Chin S et al.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 127 Issue: 4 Pages: 467-473
- DOI
  10.1016/j.jphs.2015.03.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590310
[Journal Article] 8-Methyltryptanthrin-induced differentiation of P19CL6 embryonal carcinoma cells into spontaneously beating cardiomyocyte-like cells.2014
- Author(s)
  Seya K, Yamaya A, Kamachi S, Murakami M, Kitahara H, Kawakami J, Okumura K, Murakami M, Motomura S, Furukawa K.
- Journal Title
  
  8-Methyltryptanthrin-induced differentiation of P19CL6 embryonal carcinoma cells into spontaneously beating cardiomyocyte-like cells.
  
  Volume: 77 Issue: 6 Pages: 1413-9
- DOI
  10.1021/np500108r
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460293, KAKENHI-PROJECT-26461120
[Journal Article] A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine.2014
- Author(s)
  Nakajima M, Takahashi A, Tsuji T, Furukawa K-I et al.
- Journal Title
  
  Nature Genetics
  
  Volume: 46 Issue: 9 Pages: 1012-1016
- DOI
  10.1038/ng.3045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590310, KAKENHI-PROJECT-24592194, KAKENHI-PROJECT-26293332, KAKENHI-PROJECT-26670654, KAKENHI-PROJECT-221S0001
[Journal Article] Osteogenic lineage commitment of mesenchymal stem cells from patients with ossification of the posterior longitudinal ligament.2014
- Author(s)
  Yoshifumi Harada
- Journal Title
  
  Biochem Biophis Res Commun.
  
  Volume: 443(3) Issue: 3 Pages: 1014-20
- DOI
  10.1016/j.bbrc.2013.12.080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592152, KAKENHI-PROJECT-24590310
[Journal Article] Recent Advances in Research of Human Aortic Valve Calcification.2014
- Author(s)
  Furukawa KI
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 124 Pages: 129-137
- NAID
  130003391486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590310
[Journal Article] Immunohistochemical localization of mesenchymal stem cells in ossified human spinal ligaments.2013
- Author(s)
  Shunfu Chin
- Journal Title
  
  Biochem Biophis Res Commun.
  
  Volume: 436(4) Issue: 4 Pages: 698-704
- DOI
  10.1016/j.bbrc.2013.06.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592152, KAKENHI-PROJECT-24590310
[Journal Article] 脊椎靱帯骨化における間葉系幹細胞の役割2013
- Author(s)
  小野睦、浅利亨、陳俊輔、和田簡一郎、田中利弘、古川賢一
- Journal Title
  
  脊椎脊髄ジャーナル
  
  Volume: 26 Pages: 163-168
- Data Source
  KAKENHI-PROJECT-24590310
[Journal Article] The role of CD34-negative mesenchymal stem-like cells as cellular origin on human aortic valve calcification.2013
- Author(s)
  Nomura A, Seya K, Yu Z, Daitoku K, Motomura S,Murakami M, Fukuda I, Furukawa K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 440 Issue: 4 Pages: 780-785
- DOI
  10.1016/j.bbrc.2013.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460293
[Journal Article] Mesenchymal stem cell isolation and characterization from human spinal ligaments2012
- Author(s)
  Toru Asari
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 27 Issue: 4 Pages: 1193-1199
- DOI
  10.1016/j.bbrc.2011.12.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592152, KAKENHI-PROJECT-24590310
[Journal Article] Post injury changes in the properties of mesenchymal stem cells derived from human anterior cruciate ligaments2012
- Author(s)
  Nohmi Shuya
- Journal Title
  
  Int Orthop
  
  Volume: 36 Issue: 7 Pages: 1515-1522
- DOI
  10.1007/s00264-012-1484-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500676, KAKENHI-PROJECT-24590310
[Journal Article] Contribution of bone morphogenetic protein-2 to aortic valve calcification in aged rat.2011
- Author(s)
  Seya K, Yu Z, Kanemaru K, Daitoku K, Akemoto Y, Shibuya H, Fukuda I, Okumura K, Motomura S, Furukawa K-I
- Journal Title
  
  Journal of Pharmacological Sciences 115
  
  Pages: 8-14
- NAID
  10029891345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] P2Y1 Transient Overexpression Induced Mineralization in Spinal Ligament Cells Derived from Patients with Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.2011
- Author(s)
  Tanaka S, Kudo H, Asari T, Ono A, Motomura S, Toh S, Furukawa K-I
- Journal Title
  
  Calcified Tissue International 88
  
  Pages: 263-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] TNF-α accelerates the calcification of human aortic valve interstitial cells obtained from patients with calcific aortic valve stenosis via the BMP2-Dlx5 pathway.2011
- Author(s)
  Yu Z, Seya K, Daitoku K, Motomura S, Fukuda I, Furukawa K-I
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 337
  
  Pages: 16-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Genetic differences in the osteogenic differentiation potency according to the classification of ossification of the posterior longitudinal ligament of the cervical spine.2011
- Author(s)
  Kudo H, Yokoyama T, Ono A, Numasawa T, Wada K, Tanaka T, Asari T, Ueyama K, Motomura S, Toh S, Furukawa K-I
- Journal Title
  
  Spine 36
  
  Pages: 951-957
- NAID
  10030714642
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Genetic differences in the osteogenic differentiation potency based onaccording to the classification for the ossification of the posterior longitudinal ligament of the cervical spine.2010
- Author(s)
  Kudo H, Furukawa K-I, 他11名
- Journal Title
  
  Spine (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Comparison of cardiovascular parameters between patients with ossification of posterior longitudinal ligament and patients with cervical spondylotic myelopathy.2009
- Author(s)
  Kishiya M, Furukawa K-I, Yokoyama T, Kudo H, Ono A, Numasawa T, Wada K, Toh S
- Journal Title
  
  Journal of Spinal Disorders & Techniques 22
  
  Pages: 361-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Opposite effects of two resveratrol tetramers, vitisin A and hopeaphenol on apoptosis of myocytes isolated from adult rat heart.2009
- Author(s)
  Seya K, Furukawa K-I, 他11名
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 328
  
  Pages: 90-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Comparison of cardiovascular parameters between patients with ossification of posterior longitudinal ligament and patients with cervical spondylotic myelonathy.2009
- Author(s)
  Kishiya M, Furukawa K-I, 他8名
- Journal Title
  
  Journal of Spinal Disorders & Techniques 22
  
  Pages: 361-366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Pharmacological aspect of ectopic ossification in spinal ligament tissues2008
- Author(s)
  Furukawa Ken-Ichi
- Journal Title
  
  Pharmacology & Therapeutics 118
  
  Pages: 352-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Calcification of aortic smooth muscle cells isolated from spontaneously hypertensive rats.2008
- Author(s)
  Kanemaru K, Seya K, Miki I, Motomura S, Furukawa K-I
- Journal Title
  
  Journal of Pharmacological 106
  
  Pages: 280-286
- NAID
  10024318473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] A functional RNAi screen for runx2-regulated genes corresponding to ectopic bone formation in human spinal ligaments.2008
- Author(s)
  Kishiya M, Sawada T, Kanemaru K, Kudo H, Numasawa T, Yokoyama T, Motomura S, Ueyama K, Harata S, Toh S, Furukawa K-I
- Journal Title
  
  Journal of Pharmacological Sciences 106
  
  Pages: 404-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Possible role of extracellular nucleotides in ectopic ossification of human spinal ligaments.2008
- Author(s)
  Sawada T, Kishiya M, Kanemaru K, Yokoyama T, Ueyama K, Motomura S, Toh S, Furukawa K-I
- Journal Title
  
  Journal of Pharmacological Sciences 106
  
  Pages: 152-161
- NAID
  10024317852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Pharmacological aspect of ectopic ossification in spinal ligament tissues.2008
- Author(s)
  Furukawa K-I
- Journal Title
  
  Pharmacology & Therapeutics 118
  
  Pages: 352-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590245
[Journal Article] Current topics in pharmacological research on bone metabolism2006
- Author(s)
  Ken-Ichi Furukawa, et al.
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 187-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390063
[Journal Article] Current topics in pharmacological research on bone metabolism2006
- Author(s)
  Ken-Ichi Furukawa
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 187-187
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390063
[Journal Article] Molecular basis of cctopic bone formation induced by mechanical stress.2006
- Author(s)
  Ken-Ichi Furukawa
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 187-187
- Data Source
  KAKENHI-PROJECT-16390063
[Journal Article] 難病と在宅ケア2006
- Author(s)
  古川賢一
- Journal Title
  
  脊柱靱帯骨化症の薬物治療法開発を目指して 12
  
  Pages: 11-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390063
[Journal Article] Molecular basis of ectopic bone formation induced by mechanical stress.2006
- Author(s)
  Ken-Ichi Furukawa
- Journal Title
  
  Journal of Pharmacological Science 100
  
  Pages: 201-204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390063
[Journal Article] Aiming at the development of pharmacotherapy for OPLL2006
- Author(s)
  Ken-Ichi Furukawa
- Journal Title
  
  Nanbyo to Zaitakukea 12
  
  Pages: 11-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390063
[Journal Article] メカニカルストレスと生体応答2004
- Author(s)
  古川賢一
- Journal Title
  
  化学と生物 42
  
  Pages: 286-287
- Data Source
  KAKENHI-PROJECT-16390063
[Presentation] 大動脈弁狭窄症患者から得た大動脈弁間質細胞の石灰化に対するマトリックスGlaタンパク質の抑制作用2019
- Author(s)
  瀬谷和彦 ,于　在強, 千代谷真理, 大徳和之, 元村　成, 今泉忠淳, 福田幾夫, 古川賢一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] Blood Coagulability, Vascular Morphology And Vasculogenesis Capability Of Spinal Ligament Ossification Model Mice.2019
- Author(s)
  Ichikawa Nana, Kumagai Gentaro, Wada Kanichiro, Furukawa Ken-Ichi, Ishibashi Yasuyuki
- Organizer
  ORS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10916
[Presentation] 大動脈弁狭窄症患者から得た大動脈弁間質細胞の高リン酸による石灰化誘発に対する1-methyl-2-undecyl-4(1H)-quinoloneの抑制作用2019
- Author(s)
  瀬谷　和彦、古川　賢一、千代谷真理、于　在強、菊地晴久、大徳和之、元村　成、今泉忠淳、大島吉輝、福田幾夫
- Organizer
  第48回日本心脈管作動物質学会年会
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves2019
- Author(s)
  Kazuhiko Seya, Zaiqiang Yu, Mari Chiyoya, Wei Yang, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] Role of SDF-1/CXCR4 Axis in Chemotactic Behavior of Mesenchymal Stem Cell in Ossified Human Spinal Ligaments.2019
- Author(s)
  Chin Shunfu, Furukawa Ken-Ichi, Wada Kanichiro, Kumagai Gentaro, Kudo Hitoshi, Asari Tohru, Ichikawa Nana, Araki Ryo, Ishibashi Yasuyuki
- Organizer
  ORS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10916
[Presentation] Role of SDF-1/CXCR4 Axis in Chemotactic Behavior of Mesenchymal Stem Cell in Ossified Human Spinal Ligaments.2019
- Author(s)
  Chin S, Furukawa KI et al.
- Organizer
  米国整形外科学会基礎学術集会（ORS）2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10916
[Presentation] ワルファリンは大動脈弁異所性石灰化を促進するか？：大動脈弁間質細胞を用いた検討2018
- Author(s)
  于在強、瀬谷和彦、千代谷真理、大徳和之、今泉忠淳、古川賢一、福田幾夫
- Organizer
  第48回日本心臓血管外科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10619
[Presentation] TNF-α-induces calcification of cultured human aortic valve interstitial cells obtained from patients with calcific aortic stenosis: involvement of BMP22018
- Author(s)
  Kazuhiko Seya, Zaiqiang Yu, Mari Chiyoya, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] ヒト石灰化大動脈弁から得た間質細胞においてBMP2が誘発する石灰化に対するワルファリンの影響2018
- Author(s)
  瀬谷和彦、于在強、楊　微、大徳和之、元村成、今泉　忠淳、福田幾夫、古川賢一
- Organizer
  第69回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] Isolation of Multilineage-differentiating stress enduring cells derived from mouse adipose tissue.2018
- Author(s)
  Yoshiro Nitobe、Toshihide Nagaoki, Gentaro Kumagai, Ayako Sasaki, Xizhe Liu, Taku Fujita, Kanichiro Wada, Ken-Ichi Furukawa, Yasuyuki Ishibashi
- Organizer
  Orthopeadic Research Society Annual Meeting (国際学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10917
[Presentation] 大動脈弁に局在する易石灰化性未分化細胞における遺伝的特徴の解析2017
- Author(s)
  瀬谷和彦、于在強、野村亜南、千代谷真理、大徳和之、今泉忠淳、元村成、福田幾夫、古川賢一
- Organizer
  第68回日本薬理学会北部会（山形）
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] 大動脈弁間質細胞の石灰化におけるマトリックスグラタンパク質遺伝子発現の抑制効果2017
- Author(s)
  于在強、瀬谷和彦、千代谷真理、大徳和之、今泉忠淳、元村成、福田幾夫、古川賢一
- Organizer
  第68回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-16K10619
[Presentation] LECT-1, an intrinsic inhibitor of angiogenesis decreases in mesenchymal stem cells derived from ossification of the yellow ligament (OYL) patients2017
- Author(s)
  Ishibashi H, Furukawa KI, Wada K, Tanaka T, Gentaro K, Shiozaki T, Liu X, Ishibashi Y
- Organizer
  Orthopeadic Research Society Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10916
[Presentation] The H2 blocker famotidine suppressed osteogenic differentiation of mesenchymal stem cells derived from patients with ossification of the posterior longitudinal ligament2017
- Author(s)
  Liu X, Kumagai G, Wada K, Tanaka T, Shiozaki T, Sasaki A, Furukawa KI
- Organizer
  Orthopeadic Research Society Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10916
[Presentation] Human aortic valve interstitial cells obtained from patients with calcific aortic stenosis have high sensitivity to TNF-α resulting in ectopic calcification.2017
- Author(s)
  Kazuhiko Seya, Zaiqiang Yu, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa
- Organizer
  2018 ISHR-JPN Section Meeting (Osaka)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10449
[Presentation] The role of CD34-negative mesenchymal stem-like cells as cellular origin on human aortic valve calcification.2014
- Author(s)
  Seya K, Nomura A, Yu Z, Daitoku K, Motomura S,Murakami M, Fukuda I, Furukawa K.
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25460293
[Presentation] 脊柱靭帯組織の異所性骨化に於ける間葉系幹細胞局在変化の意義2014
- Author(s)
  古川賢一
- Organizer
  第６５回　日本薬理学会北部会
- Place of Presentation
  福島市
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] 脊柱靭帯の異所性骨化患者から得られた間葉系幹細胞の骨分化能の亢進2014
- Author(s)
  古川賢一他
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] 後縦靭帯骨化症においてエピジェネティクスの果たす役割の検討2013
- Author(s)
  千葉紀之、古川賢一他
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] 頚椎後縦靱帯骨化症患者由来間葉系幹細胞の骨分化能に関連する因子の検討2013
- Author(s)
  原田義史、古川賢一他
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] 脊柱靱帯骨化症における間葉系幹細胞の局在及び制御因子の発現の免疫組織化学的な検討2013
- Author(s)
  陳俊輔、古川賢一他
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] ヒト脊柱靭帯由来間葉系幹細胞の分離・同定2012
- Author(s)
  浅利享、古川賢一、陳俊輔、小野睦、田中利弘
- Organizer
  日本骨代謝学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] 免疫組織化学染色法によるヒト脊柱靱帯における間葉系幹細胞の同定ならびにその局在の検討2012
- Author(s)
  陳俊輔、古川賢一、浅利亨、小野睦、田中利弘
- Organizer
  日本骨代謝学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590310
[Presentation] Expression of GREM-1, one of the BMP antagonists, is significantly suppressed in the spinal ligament cells derived from patients with ossification of the posterior longitudinal ligament of the cervical spine.2011
- Author(s)
  Tanaka S, Asari T, Harada Y, Ono A, Numasawa T, Wada K, Yamasaki Y, Motomura S, Toh S, Furukawa K.-I.
- Organizer
  57th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Long Beach California, USA
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] TNF-αは石灰化動脈弁狭窄症患者から得た動脈弁間質細胞の石灰化をBMP2-Dlx5経路を介して促進する2011
- Author(s)
  于在強,瀬谷和彦,大徳和之,元村成,福田幾夫,古川賢一
- Organizer
  日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] P2Y1の一過性過剰発現は脊柱靭帯骨化症患者由来の脊柱靭帯細胞の石灰化を誘発する2010
- Author(s)
  田中直,浅利享,小野睦,沼沢拓也,藤哲,瀬谷和彦,元村成,古川賢一
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] TNF-αはNF-kB経路を介して石灰化大動脈弁狭窄症患者由来の大動脈弁間質細胞の石灰化を促進する2010
- Author(s)
  于在強,瀬谷和彦,大徳和之,元村成,福田幾夫,古川賢一
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 脊柱後縦靱帯骨化症患者におけるP2Y1受容体の病態生理学的役割-過剰発現による解析2010
- Author(s)
  田中直,古川賢一、浅利享,小野睦,沼沢拓也,瀬谷和彦,藤哲,元村成
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 高血圧によるラット大動脈平滑筋の異所性石灰化における一酸化窒素の役割2010
- Author(s)
  古川賢一
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 脊柱靱帯骨化症患者の脊柱靭帯由来細胞ではBMP-2抑制遺伝子であるGrem-1の発現が有意に低下している2010
- Author(s)
  田中直、小野睦、沼沢拓也、和田簡一郎、山崎義人、元村成、藤哲、古川賢一
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] Genetic differences in osteogenic differentiation potency based on the classification for the ossification of the posterior longitudinal ligament of the cervical spine.2010
- Author(s)
  Kudo H, Furukawa K.-I., Ono A, Numasawa T, Wada K, Tanaka S, Asari T, Motomura S, Toh S
- Organizer
  56th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  New Orleans, Lousiana, USA(Sympodium speaker)
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] Genetic differences in osteogenic differentiation potency based on the classification for the ossification of the posterior longitudinal ligament of the cervical spine2010
- Author(s)
  Kudo H, Furukawa K-I, 他9名
- Organizer
  56rd Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  New Orleans, Lousiana, USA
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] Genetic Differences in the Osteogenic Differentiation Potency according to the Classification of the Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.2010
- Author(s)
  Kudo H, Ono A, Numasawa T, Wada W, Tanaka S, Asari1 T, Toh S, Motomura S, Furukawa K.-I.
- Organizer
  37th European Symposium on Calcified Tissues
- Place of Presentation
  Glasgow, Great Britain
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] Genetic Association in Progression of the Ossification Area of the Posterior Longitudinal Ligament of the Cervical Spine2009
- Author(s)
  Furukawa Ken-Ichi
- Organizer
  55rd Annual Meeting of the Orthopaedic Research Society(アメリカ骨代謝学会年会)
- Place of Presentation
  アメリカ合衆国ネバダ州ラスベガス
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 脊椎後縦靭帯骨化症患者におけるP2Y1受容体の病態生理学的役割一過剰発現による解析2009
- Author(s)
  古川賢一
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 高血圧によるラット大動脈平滑筋の異所性石灰化2009
- Author(s)
  古川賢一
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 頚椎後縦靱帯骨化症分類による骨分化能の違い2009
- Author(s)
  工藤整,小野睦,沼沢拓也,和田簡一郎,田中直,浅利享,元村成,藤哲,古川賢一
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 頚椎後縦靱帯骨化症分類に基づいた遺伝子発現の検討2009
- Author(s)
  古川賢一
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜会議センター
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] Genetic Association in Progression of the Ossification Area of the Posterior Longitudinal Ligament of the Cervical Spine.2009
- Author(s)
  Kudo H, Furukawa K.-I., Ono A, Numasawa T, Wada K, Tanaka S, Motomura S, Toh S
- Organizer
  55th Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Las Vegas, Nevada, USA
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 頚椎後縦靱帯骨化症分類に基づいた遺伝子発現の検討2009
- Author(s)
  工藤整、田中直、沼沢拓也、小野睦、和田簡一郎、浅利亨、瀬谷和彦、三木いづみ、籐哲、元村成、古川賢一
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 脊椎後縦靱帯骨化症患者におけるP2Y1受容体の病態生理学的役割-過剰発現による解析2009
- Author(s)
  田中直、工藤整、小野睦、沼沢拓也、瀬谷和彦、三木いづみ、籐哲、元村成、古川賢一
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 高血圧自然発症ラットの大動脈平滑筋細胞の易石灰化2008
- Author(s)
  古川賢一
- Organizer
  第26回日本骨代謝学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] 頚椎後縦靱帯骨化症分類に基づいた遺伝子発現の検討2008
- Author(s)
  古川賢一
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590245
[Presentation] cDNA microarray screening of genes related to osteogenic feature of mesenchymal stem cells from patients with ossifi ed spinal ligament
- Author(s)
  古川賢一、千葉紀之、浅利亨、陳俊輔、原田義史、元村成、村上学、石橋恭之
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460293
[Presentation] Both warfarin and vitamin K stimulate the ectopic calcifi cation of human aortic valve interstitial cells through binding to pregnane X receptor
- Author(s)
  瀬谷和彦、于在強、野村亜南、大徳和之、元村成、村上学、福田幾夫、古川賢一
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460293
[Presentation] 大動脈弁間質細胞の高リン酸誘発性異所性石灰化に対する1-methyl-2-undecyl-4(1H)-quinoloneの抑制作用
- Author(s)
  瀬谷和彦，于　在強，菊地　晴久，大徳　和之，福田　幾夫，村上　学，大島　吉輝，古川　賢一
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460293

1. OHIZUMI Yasushi (00006355)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
2. MATSUNAGE Kimihiro (90222306)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. NAKAHATA Norimichi (60045804)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
4. SEYA Kazuhiko (40281919)

# of Collaborated Projects: 6 results

# of Collaborated Products: 30 results
5. IWATA Yuko (80171908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SHIGEKAWA Munekazu (00113738)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. MATSUOKA Setsu (40238986)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. YAGIMUMA Toshiko (00250803)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. OSHIMA Yoshiteru (00111302)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. WADA Kanichiro (20431447)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
11. murakami manabu (80302090)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
12. Daitoku Kazuyuki (50374822)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
13. 福田幾夫 (50344594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
14. NUMASAWA Takuya (80396407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
15. ONO Atsushi (40400155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. ONO Kyoichi (70185635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. OHBA Takayoshi (80431625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUGITA Chiharu (70632694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKATANI Keigo (60281979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MOTOMURA Shigeru (40091756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKAHASHI Satoshi (10236276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SAKAI Tetsuhiro (80205707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. INOUE Ituro (00192500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. OKADA Akihiro (90312488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Kumagai Gentaro (90529679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. 北条博史 (90004621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 柳田俊彦 (60295227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 根本隆行 (90506833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ISHIKAWA Kiyofumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. IKEMOTO Fumihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Furukawa Kenichi 古川 賢一

FURUKAWA Ken-Ichi 古川 賢一

FURUKAWA Kenichi 古川 賢一

FURUKAWA Ken-ichi 古川 賢一

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Elucidation of the mechanism of mesenchymal stem cell abnormality causing ossification of spinal ligament and target search of therapeutic agents based on the mechanismPrincipal Investigator

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Role of mesenchymal stem cells as a cause of ectopic ossification of spinal ligamentPrincipal Investigator

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Exploring molecular targets for the establishment of drug therapy for the ossification of the posterior longitudinal ligament of the spinePrincipal Investigator

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Analysis of genes related to the ectopic bone formation induced by mechanical stress and search for drugs targeting the genes.Principal Investigator

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Screening and characterization of new regulation factor of Ca^<2+> release channelsPrincipal Investigator

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リアノジンレセプターカルシウム遊離チャンネルの分子調節機構の解析Principal Investigator

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Furukawa Kenichi 古川賢一

FURUKAWA Ken-Ichi 古川賢一

FURUKAWA Kenichi 古川賢一

FURUKAWA Ken-ichi 古川賢一