IWANARI Hiroko 岩成宏子

Researcher Number	20176556
Other IDs
Affiliation (based on the past Project Information) *help	2017: 東京大学, 先端科学技術研究センター, 准教授 2013: 東京大学, 先端科学技術研究センター, 准教授 2009 – 2012: 東京大学, 先端科学技術研究センター, 特任助教
Review Section/Research Field	Except Principal Investigator Biomolecular chemistry / Living organism molecular science
Keywords	Except Principal Investigator RNAプロセッシング / 細胞周期 / スプライシング / コンピュータシミュレーション / 分子認識 / タンパク質相互作用 / ヒストン / 血管内皮細胞 / オルタナティブスプライシング / パターン認識受容体 … More / 自然免疫 / ペントラキシン / ヒストン障害 / 敗血症 / モノクローナル抗体 / 核タンパク質 / 軟X線顕微鏡 / 核内受容体 / 軟Ｘ線顕微鏡 / 生体イメージング / ヒストン修飾 / 核微細構造 / クロマチン修飾 / 核小体 / 核スペックル / 転写調節 / 複合体解析 / プロテオミクス Less

Dynamics of Molecular Pattern Recognition in Protein Interaction
- Principal Investigator
  
  HAMAKUBO TAKAO
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo
Dynamic Proteomics of Transcriptional and Nuclear Architecture
- Principal Investigator
  
  HAMAKUBO Takao
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation Patent

[Journal Article] Role of METTL20 in regulating β-oxidation and heat production in mice under fasting or ketogenic conditions2018
- Author(s)
  Shimazu Tadahiro、Furuse Tamio、Balan Shabeesh、Yamada Ikuko、Okuno Shuzo、Iwanari Hiroko、Suzuki Takehiro、Hamakubo Takao、Dohmae Naoshi、Yoshikawa Takeo、Wakana Shigeharu、Shinkai Yoichi
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 1179-1179
- DOI
  10.1038/s41598-018-19615-4
- NAID
  120006539598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07144, KAKENHI-PROJECT-17K18719, KAKENHI-PROJECT-25220205
[Journal Article] Kinetic exclusion assay of monoclonal antibody affinity to the membrane protein Robo1 displayed on baculovirus.2016
- Author(s)
  Kusano-Arai O, Fukuda R, Kamiya W, Iwanari H, Hamakubo T.
- Journal Title
  
  Anal Biochem.
  
  Volume: Apr 16 Pages: 30027-6
- DOI
  10.1016/j.ab.2016.04.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220205
[Journal Article] Suppression of Slit2/ROBO1 mediated HUVEC migration by Robo42016
- Author(s)
  Enomoto S, Mitsui K, Kawamura T, Iwanari H, Daigo K, Horiuchi K, Minami T, Kodama T, Hamakubo T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Issue: 4 Pages: 797-802
- DOI
  10.1016/j.bbrc.2015.12.075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01348, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26290035
[Journal Article] Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial temporal lobe epilepsy.2015
- Author(s)
  Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, Takahashi N, Iwanari H, Mochizuki Y, Hamakubo T, Imoto K, Meijer D, Watanabe M, Fukata M
- Journal Title
  
  Nat Med
  
  Volume: 21 Issue: 1 Pages: 19-26
- DOI
  10.1038/nm.3759
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-24108007, KAKENHI-PUBLICLY-25110733, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25890021, KAKENHI-PROJECT-26291045, KAKENHI-PROJECT-26460250, KAKENHI-PROJECT-24220007
[Journal Article] Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.2015
- Author(s)
  Kurosawa K, Misu T, Takai Y, Sato DK, Takahashi T, Abe Y, Iwanari H, Ogawa R, Nakashima I, Fujihara K, Hamakubo T, Yasui M, Aoki M.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 4 Issue: 1 Pages: 783-783
- DOI
  10.1186/s40478-015-0259-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09332, KAKENHI-PROJECT-15K19473, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-26293205
[Journal Article] Crystal structure of the anion exchanger domain of human erythrocyte band 32015
- Author(s)
  Arakawa T, Kobayashi-Yurugi T, Alguel Y, Iwanari H, Hatae H, Iwata M, Abe Y, Hino T, Ikeda-Suno C, Kuma H, Kang D, Murata T, Hamakubo T, Cameron AD, Kobayashi T, Hamasaki N, Iwata S
- Journal Title
  
  Science
  
  Volume: 350 Issue: 6261 Pages: 680-684
- DOI
  10.1126/science.aaa4335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08632, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25253041, KAKENHI-PROJECT-25460398, KAKENHI-PROJECT-26305027, KAKENHI-PROJECT-25711004
[Journal Article] Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses.2015
- Author(s)
  Nakayama T, Mizohata E, Yamashita T, Nagatoishi S, Nakakido M, Iwanari H, Mochizuki Y, Kado Y, Yokota Y, Satoh R, Tsumoto K, Fujitani H, Kodama T, Hamakubo T, Inoue T.
- Journal Title
  
  Protein Sci
  
  Volume: 24 Issue: 3 Pages: 328-340
- DOI
  10.1002/pro.2619
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
[Journal Article] High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.2015
- Author(s)
  Miyazaki-Komine K, Takai Y, Huang P, Kusano-Arai O, Iwanari H, Misu T, Koda K, Mitomo K, Sakihama T, Toyama Y, Fujihara K, Hamakubo T, Yasui M, Abe Y.
- Journal Title
  
  Br J Pharmacol
  
  Volume: 173 Issue: 1 Pages: 103-103
- DOI
  10.1111/bph.13340
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09332, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-26293205, KAKENHI-PROJECT-15K19473
[Journal Article] Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function2015
- Author(s)
  Gin-Fu Chen, Varadarajan Sudhahar, Seock-Won Youn, Archita Das, Jaehyung Cho, Tetsuro Kamiya, Norifumi Urao, Ronald D. McKinney, Bayasgalan Surenkhuu, Takao Hamakubo, Hiroko Iwanari, Senlin Li, John W. Christman, Saran Shantikumar, Gianni D. Angelini, Costanza Emanueli, Masuko Ushio-Fukai, Tohru Fukai
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 14780-14780
- DOI
  10.1038/srep14780
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460070, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
[Journal Article] MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells.2015
- Author(s)
  Tsuyama J, Bunt J, Richards LJ, Iwanari H, Mochizuki Y, Hamakubo T, Shimazaki T*, Okano H*
- Journal Title
  
  Stem Cell Reports
  
  Volume: 5 Issue: 3 Pages: 365-377
- DOI
  10.1016/j.stemcr.2015.06.006
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06719, KAKENHI-PROJECT-25220205
[Journal Article] Analysis of the subcellular localization of the human histone methyltransferase SETDB12015
- Author(s)
  Tachibana K, Gotoh E, Kawamata N, Ishimoto K, Uchihara Y, Iwanari H, Sugiyama A, Kawamura T, Mochizuki Y, Tanaka T, Sakai J, Hamakubo T, Kodama T, Doi T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 465 Issue: 4 Pages: 725-731
- DOI
  10.1016/j.bbrc.2015.08.065
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22229009, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-15H02896, KAKENHI-PROJECT-15H04644, KAKENHI-PROJECT-26560395, KAKENHI-PROJECT-25860253, KAKENHI-PROJECT-26870346, KAKENHI-PUBLICLY-26116708
[Journal Article] 90Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts.2015
- Author(s)
  Fujiwara K, Koyama K, Suga K, Ikemura M, Saito Y, Hino A, Iwanari H, Kusano-Arai O, Mitsui K, Kasahara H, Fukayama M, Kodama T, Hamakubo T, Momose T.
- Journal Title
  
  PLoS One.
  
  Volume: May 27;10(5) Issue: 5 Pages: e0125468-e0125468
- DOI
  10.1371/journal.pone.0125468
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220205
[Journal Article] Structure and mechanism of the mammalian fructose transporter GLUT52015
- Author(s)
  Nomura N, Verdon G, Kang HJ, Shimamura T, Nomura Y, Sonoda Y, Hussien SA, Qureshi AA, Coincon M, Sato Y, Abe H, Nakada-Nakura Y, Hino T, Arakawa T, Kusano-Arai O, Iwanari H, Murata T, Kobayashi T, Hamakubo T, Kasahara M, Iwata S, Drew D
- Journal Title
  
  Nature
  
  Volume: 526 Issue: 7573 Pages: 397-401
- DOI
  10.1038/nature14909
- NAID
  120005657713
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06968, KAKENHI-PLANNED-24108007, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25711004
[Journal Article] Immunostaining of oxidized DJ-1 in human and mouse brains.2014
- Author(s)
  Saito, Y., T. Miyasaka, H. Hatsuta, K. Takahashi-Niki, K. Hayashi, Y. Mita, O. Kusano-Arai, H. Iwanari, H. Ariga, T. Hamakubo, Y. Yoshida, E. Niki, S. Murayama, Y. Ihara and N. Noguchi
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 73 Issue: 7 Pages: 714-728
- DOI
  10.1097/nen.0000000000000087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24790773, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25670084
[Journal Article] Proteoliposome-based selection of a recombinant antibody fragment against the human M2 muscarinic acetylcholine receptor.2014
- Author(s)
  Suharni, Nomura Y, Arakawa T, Hino T, Abe H, Nakada-Nakura Y, Sato Y, Iwanari H, Shiroishi M, Asada H, Shimamura T, Murata T, Kobayashi T, Hamakubo T, Iwata S, Nomura N.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother
  
  Volume: 33 Issue: 6 Pages: 378-385
- DOI
  10.1089/mab.2014.0041
- NAID
  120005530933
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25650023, KAKENHI-PROJECT-25709080, KAKENHI-PUBLICLY-26102725
[Journal Article] A 90Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy.2014
- Author(s)
  Fujiwara K, Koyama K, Suga K, Ikemura M, Saito Y, Hino A, Iwanari H, Kusano-Arai O, Mitsui K, Kasahara H, Fukayama M, Kodama T, Hamakubo T, Momose T.
- Journal Title
  
  EJNMMI Research
  
  Volume: 4 Issue: 1 Pages: 29-29
- DOI
  10.1186/s13550-014-0029-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
[Journal Article] G protein-dependent basal and evoked endothelial cell vWF secretion.2014
- Author(s)
  Rusu L, Andreeva A, Visintine DJ, Kim K, Vogel SM, Stojanovic-Terpo A, Chernaya O, Liu G, Bakhshi FR, Haberichter SL, Iwanari H, Kusano-Arai O, Suzuki N, Hamakubo T, Kozasa T, Cho J, Du X, Minshall RD.
- Journal Title
  
  Blood
  
  Volume: 123 Issue: 3 Pages: 442-450
- DOI
  10.1182/blood-2013-03-489351
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24390060, KAKENHI-PROJECT-24591540, KAKENHI-PROJECT-25220205
[Journal Article] Generation of antibodies against membrane proteins.2014
- Author(s)
  Hamakubo T, Kusano-Arai O, Iwanari H.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1844 Issue: 11 Pages: 1920-1924
- DOI
  10.1016/j.bbapap.2014.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
[Journal Article] Novel role of copper transport protein antioxidant-1 in neointimal formation after vascular injury.2013
- Author(s)
  Kohno T
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: Apr; 33　(4) Issue: 4 Pages: 805-813
- DOI
  10.1161/atvbaha.112.300862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-24790785, KAKENHI-PROJECT-25220205
[Journal Article] A mesodermal factor, T, specifies mouse germ cell fate by directly activating germline determinants2013
- Author(s)
  Aramaki, S., Hayashi, K., Kurimoto, K., Ohta, H., Yabuta, Y., Iwanari, H., Mochizuki, Y., Hamakubo, T., Kato, Y., Shirahige, K., and Saitou, M
- Journal Title
  
  Developmental Cell
  
  Volume: 27 Issue: 5 Pages: 516-529
- DOI
  10.1016/j.devcel.2013.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21677003, KAKENHI-PROJECT-24681039, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25650065, KAKENHI-PROJECT-25650077
[Journal Article] Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.2013
- Author(s)
  Horiuchi K, Kawamura T, Iwanari H, Ohashi R, Naito M, Kodama T, Hamakubo T
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 46 Pages: 33292-33302
- DOI
  10.1074/jbc.m113.500397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205
[Journal Article] Establishment of Monoclonal Antibodies Against the Extracellular Domain That Block Binding of NMO-IgG to AQP42013
- Author(s)
  Miyazaki K.
- Journal Title
  
  J. Neuroimmunol.
  
  Volume: 未定 Issue: 1-2 Pages: 107-16
- DOI
  10.1016/j.jneuroim.2013.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590940, KAKENHI-PROJECT-24591609, KAKENHI-PROJECT-25220205
[Journal Article] A Novel Monoclonal Antibody Against the C-Terminal Region of Aquaporin-42013
- Author(s)
  1. Ramadhanti J
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother
  
  Volume: 32 Issue: 4 Pages: 270-276
- DOI
  10.1089/mab.2013.0007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229008, KAKENHI-PROJECT-24591247, KAKENHI-PROJECT-25220205
[Journal Article] G protein-coupled receptor inactivation by an allosteric inverse-agonist antibody2012
- Author(s)
  Hino T., et al
- Journal Title
  
  Nature
  
  Volume: 482 Issue: 7384 Pages: 237-40
- DOI
  10.1038/nature10750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22659059, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074
[Journal Article] A method of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells2011
- Author(s)
  Iwanari H
- Journal Title
  
  J Immunol Method
  
  Volume: Jun30 ; 369(1-2) Issue: 1-2 Pages: 108-14
- DOI
  10.1016/j.jim.2011.04.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-21591348
[Journal Article] A method of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells2011
- Author(s)
  Iwanari H, Nakada-Nakura Y, Kusano-Arai O, Suzuki N, Kodama T, Sakihama T, Hamakubo T
- Journal Title
  
  Journal of Immunological Method
  
  Volume: in press(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Epigenetically coordinated GATA2 binding is necessary for endothelium specific endomucin sxpression2011
- Author(s)
  Kanki Y, Kohro T, Jiang S, Tsutsumi S, Mimura I, Suehiro J, Wada Y, Ohta Y, Ihara S, Iwanari H, Naito M, Hamakubo T, Aburatani H, Kodama T, Minami T.
- Journal Title
  
  The EMBO Journal in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Epigenetically coordinated GATAT2 binding is necessary for endothelium-specific endomucin expression2011
- Author(s)
  Kanki Y, Kohro T, Jiang S, Tsutsumi S, Mimura I, Suehiro J, Wada Y, Ohta Y, Ihara S, Iwanari H, Naito M, Hamakubo T, Aburatani H, Kodama T, Minami T
- Journal Title
  
  EMBO J
  
  Volume: 30 Issue: 13 Pages: 2582-95
- DOI
  10.1038/emboj.2011.173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02514, KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-20221010, KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-22310117, KAKENHI-PROJECT-22700309, KAKENHI-PROJECT-22700875, KAKENHI-PUBLICLY-23125503, KAKENHI-PROJECT-23659050
[Journal Article] Epigenetically coordinated GATA2binding is necessary for endothelium specific endomucin sxpression2011
- Author(s)
  Kanki Y, Kohro T, Jiang S, Tsutsumi S, Mimura I, Suehiro J, Wada Y, Ohta Y, Ihara S, Iwanari H, Naito M, Hamakubo T, Aburatani H, Kodama T, Minami T.
- Journal Title
  
  The EMBO Journal
  
  Volume: in press(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients.2009
- Author(s)
  Saito Y, Hamakubo T, Iwanari H, Mochizuki Y, Kinumi T, Noguchi N, Kodama T, Niki E, et al.
- Journal Title
  
  Neurosci Lett. Nov 6 ; 465(1)
  
  Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Single chain variable fragment against nicastrin inhibits the gamma-secretase activity.2009
- Author(s)
  Hayashi I, Iwanari H, Kodama T, Hamakubo T, Li T, Wong PC, Tomita T, Iwatsubo T., et al.
- Journal Title
  
  J Biol Chem. Oct 9 ; 284(41)
  
  Pages: 27838-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Expression of the mouse PR domain protein Prdm8 in the developing central nervous system.2009
- Author(s)
  Komai T, Iwanari H, Mochizuki Y, Hamakubo T, Shinkai Y.
- Journal Title
  
  Gene Expr Patterns. Oct ; 9(7)
  
  Pages: 503-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95.2009
- Author(s)
  Noritake J, Fukata Y, Iwanaga T, Hosomi N, Tsutsumi R, Matsuda N, Tani H, Iwanari H, Mochizuki Y, Kodama T, Matsuura Y, Bredt DS, Hamakubo T, Fukata M.
- Journal Title
  
  J Cell Biol. Jul 13 ; 186(1)
  
  Pages: 147-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Journal Article] Immunohistochemical staining for P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha may complement mucin phenotype of differentiated-type early gastric carcinoma.2009
- Author(s)
  Takano K, Hasegawa G, Jiang S, Kurosaki I, Hatakeyama K, Iwanari H, Tanaka T, Hamakubo T, Kodama T, Naito M.
- Journal Title
  
  Pathol Int. Jul ; 59(7)
  
  Pages: 462-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221010
[Patent] 含硫アミノ酸残基を含むポリペプチドに対する抗体2012
- Inventor(s)
  斎藤芳郎、野口範子、浜窪隆雄、岩成宏子、二木鋭雄、吉田康一、新井修
- Industrial Property Rights Holder
  学校法人同志社、国立大学法人東京大学
- Industrial Property Number
  2012-028138
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] ヒストンの血管内皮細胞障害を阻害するPTX3の凝集パターン解析2017
- Author(s)
  早田敬太、中木戸誠、太期健二、高松佑一郎、山下雄史、岩成宏子、津本浩平、浜窪隆雄
- Organizer
  2017年度生命科学系会合同年次大会
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] Extracellular Histones on Endothelial Microparticles for Diagnosis of Endothelial Dysfunction2016
- Author(s)
  Keita Soda, Takeshi Kawamura, Osamu K-Arai, Hiroko Iwanari and Takao Hamakubo.
- Organizer
  第45回　日本免疫学会学術集会
- Place of Presentation
  沖縄、日本
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] Protective Effect of Pentraxin 3 in Animal Models of Sepsis2015
- Author(s)
  Takao Hamakubo,Rie Fukuda,Hiroko Iwanari, ,Keita Soda,Kenji Daigo
- Organizer
  Targeting Ebola Paris2015
- Place of Presentation
  パリ（フランス）
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] 抗原ペプチドへの蛋白質融合が抗原－抗体相互作用に及ぼす影響の熱力学的評価2014
- Author(s)
  宮鍋一紘、秋葉宏樹、中木戸誠、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] 難溶性蛋白質KAP8.1の溶液状態と粉末状態の多面的な解析による特徴付け2014
- Author(s)
  Ganbat Javkhlan、松長遼、秋葉宏樹、下村裕、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways2013
- Author(s)
  望月康弘,大橋瑠子,川村猛,岩成宏子,児玉龍彦,内藤眞,浜窪隆雄
- Organizer
  第86回日本生化学学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-25220205
[Presentation] A methpd of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells2011
- Author(s)
  Hiroko Iwanari
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] Molecular modeling and analysis for antigen-antibodyby homology modeling and molecular dynamics simulation2010
- Author(s)
  Takamatsu Y, Fujitani H, Iwanari H, Tsumoto K, Kodama T, Hamakubo T
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] CDGAPはROBO1と相互作用して血管内皮細胞のSLIT2依存的な遊走に関与する2010
- Author(s)
  根本悟士, 川村猛, 岩成宏子, 太期健二, 堀内恵子, 南敬, 児玉龍彦, 浜窪隆雄
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] アンジオテンシンIIタイプ2受容体刺激によるCOX-2発現はAT2総合作用蛋白質を介する2010
- Author(s)
  中川清, 早田敬太, 浅田健, 岩成宏子, 新井修, 中田淑子, 児玉龍彦, 稲上正, 浜窪隆雄
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] The role of the G13~RH-RhoGEF signal pathway in differentiation of human myeloid HL60 leukemia cells2010
- Author(s)
  Suzuki N, Kawamura T, Iwanari H, Mochizuki Y, Hamakubo T, Kozasa T
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] マウス、ヒト膵癌における核内受容体の発現2009
- Author(s)
  姜淑英、大橋瑠子、岩成宏子、内藤眞、浜窪隆雄
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] ヒト肝芽腫細胞株HepG2における核内ステロイド受容体群の発現と細胞内局在。がん治療に向けた抗体分子デザイン2009
- Author(s)
  大橋瑠子、姜淑英、岩成宏子、内藤眞
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20221010
[Presentation] バキュロウイルスgp64ディスプレイシステムを用いた転写共役因子に対するモノクローナル抗体の作製2008
- Author(s)
  秋山恵麻、橘敬祐、谷本恵一、山崎大典、石本憲司、岩成宏子、田中十志也、望月康弘、酒井寿郎、浜窪隆雄、児玉龍彦、土井健史
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20221010

1. HAMAKUBO Takao (90198797)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
2. KAWAMURA Takeshi (70306835)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. DAIGO Kenji (20466866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. HORIUCHI Keiko (00456203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. NAITO Makoto (30045786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. MIYOSHI Motosuke (40345137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IHARA Shigeo (30345136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. MOCHIZUKI Yasuhiro (80282523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. SAKIHAMA Toshiko (70187061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. OHTA Yoshihiro (80436592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. OHASHI Riuko (20447600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. Fujitani Hideaki (50417151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Nagatoishi Satoru (30550248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Yamashita Takefumi (50615622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 篠田恵子 (80646951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 津本浩平 (90271866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. KUMA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. KAMIYA Tetsuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. TSUYAMA Jun

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# of Collaborated Products: 1 results
20. FURUSE Tamio

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# of Collaborated Products: 1 results
21. IWATA So

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. SHIMAMURA Tatsuro

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# of Collaborated Products: 1 results
23. CHANG Kyungho

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# of Collaborated Products: 1 results
24. 深田正紀

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# of Collaborated Products: 1 results
25. 阿部修

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# of Collaborated Products: 1 results
26. 渡辺雅彦

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# of Collaborated Products: 1 results
27. 高橋良輔

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# of Collaborated Products: 2 results
28. 久保義弘

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# of Collaborated Products: 2 results
29. 青木茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 高橋淑子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. 青木正志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 三須建郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
33. 濱崎直孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 山下裕玄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 齋藤実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 齊藤祐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 吉田明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 村山繁雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 饗場篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 斎藤泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 斎藤通紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 島崎琢也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 酒井寿郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 野村紀通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 南敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

IWANARI Hiroko 岩成 宏子

Research Projects

Research Products

Co-Researchers

Dynamics of Molecular Pattern Recognition in Protein Interaction

Principal Investigator

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Research Institution

Dynamic Proteomics of Transcriptional and Nuclear Architecture

Principal Investigator

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[Journal Article] Role of METTL20 in regulating β-oxidation and heat production in mice under fasting or ketogenic conditions2018

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DOI

NAID

Data Source

[Journal Article] Kinetic exclusion assay of monoclonal antibody affinity to the membrane protein Robo1 displayed on baculovirus.2016

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DOI

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[Journal Article] Suppression of Slit2/ROBO1 mediated HUVEC migration by Robo42016

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DOI

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[Journal Article] Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial temporal lobe epilepsy.2015

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[Journal Article] Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody.2015

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[Journal Article] Crystal structure of the anion exchanger domain of human erythrocyte band 32015

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[Journal Article] Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses.2015

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DOI

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[Journal Article] High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.2015

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[Journal Article] Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function2015

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[Journal Article] MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells.2015

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[Journal Article] Analysis of the subcellular localization of the human histone methyltransferase SETDB12015

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[Journal Article] 90Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts.2015

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[Journal Article] Structure and mechanism of the mammalian fructose transporter GLUT52015

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IWANARI Hiroko 岩成宏子