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Mukaida Keiko  向田 圭子

ORCIDConnect your ORCID iD *help
… Alternative Names

向田 圭子  ムカイダ ケイコ

KEIKO MUKAIDA  向田 圭子

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Researcher Number 20182066
External Links
Affiliation (Current) 2025: 広島大学, 病院(医), 寄附講座教授
Affiliation (based on the past Project Information) *help 2023 – 2025: 広島大学, 病院(医), 寄附講座教授
1994: 広島大学, 医学部, 助手
1994: 広島大学, 医学部・附属病院, 助手
1990: Hiroshima University, Medical Hospital Research Associate, 医学部・附属病院・手術部, 助手
1988 – 1989: 広島大学, 医学部附属病院, 助手 … More
1988 – 1989: Instructor, Department of Anesthesiology, Hiroshima University, School of Medici, 医学部附属病院麻酔科, 助手
1987: 広島大学, 医学部付属病院(麻酔学), 助手
1986: 広島大学, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 55050:Anesthesiology-related / 麻酔学 / Anesthesiology/Resuscitation studies
Except Principal Investigator
Basic Section 55050:Anesthesiology-related / 麻酔学 / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
骨格筋 / 悪性高熱症 / 遺伝子 / CACNA1S / RYR1 / カルシウム / 遺伝子パネル検査 / Metabolite / Inorganic Fluoride / Enflurane … More / Sevoflurane / 薬動力学 / フッ素 / 吸入麻酔薬 / エンフルレン / 代謝産物 / 無機フッ素 / セボフルレン / スキンドファイバー / Ca-induced Ca release … More
Except Principal Investigator
悪性高熱症 / リアノジン受容体 / 吸入麻酔薬 / PCR / 遺伝子パネル検査 / トリアジン / カルセケストリン1 / Incidence of MH in Japan / Statistical Analysis / Local anesthetics narcotics / Volatile narcotics / Normal range of human skeletal muscle / Ca^<2+>-induced Ca^<2+> release (CICR) / Skinned Fiber Test / Malignant Hyperthermia / 悪性症候群 / Ca-tnduced Ca release(CICR) / スキンドファイバー法 / 正常値 / アルコ-ル類 / 麻酔系鎮痛薬 / Ca-induced Ca release(CICR) / 統計的解析 / ヒト正常値 / Ca^<2+>ーinduced Ca^<2+> release(CICR) / 発症頻度 / 統計学的解析 / 局所麻酔薬 / ヒト骨格筋:正常値 / スキンドファイバ-法 / ^<2+>ーinduced Ca^<2+> release(CICR) / Free Radical / Dehalogenation / Hepatotoxicity / Lipid Peroxydation / Anesthetic / ハロセン / ラジカル / ラジカル反応 / 嫌気的脱ハロゲン化反応 / 肝障害 / 脂質過酸化 / Polymorphonuclear Leuckocytes(PMNLs) / Surgical patients / 感染防禦機能 / 好中球貪食殺菌能 / Nitroblve tetrazolium還元反応 / NBT還元反応 / 好中球貧食殺菌能 / ritroblve Tetrazolivm(NBT)還元反応 / 多核白血球貧食殺菌能 / 手術疾患 / Nitroblue Tetrazolium(NBT)還元反応 / 多核白血球貪食殺菌能 / 手術患者 / Skinned fiber / Skeletal muscle / Genetic linkage analysis / Gene / Malignant hyperthermia / Ca-induced Ca release / スキンドファイバー / 骨格筋 / 連鎖解析 / 遺伝子 Less
  • Research Projects

    (10 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (17 People)
  •  全ゲノムシークエンスによる悪性高熱症の新規原因遺伝子変異の検索とその機能解析

    • Principal Investigator
      三好 寛二
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  カルセケストリン1遺伝子変異が骨格筋内カルシウム動態に与える影響の調査

    • Principal Investigator
      野田 祐子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  Search for novel variants and their functional analysis by malignant hyperthermia-associated gene panel testPrincipal Investigator

    • Principal Investigator
      向田 圭子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  尿中細胞を用いた悪性高熱症の無侵襲診断法の確立

    • Principal Investigator
      近藤 隆志
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hiroshima University
  •  筋線維タイプの違いによるカルシウムによるカルシウム放出機構の差に関する研究Principal Investigator

    • Principal Investigator
      向田 圭子
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hiroshima University
  •  Analysis of genetic linkage in malignant hyperthermia susceptible families in Japan

    • Principal Investigator
      KAWAMOTO Masashi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Basic Studies on the Excretion of Inorganic Fluoride, a Metabolite Volatile AnestheticsPrincipal Investigator

    • Principal Investigator
      MUKAIDA Keiko
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      Hiroshima University
  •  Studies on the Prophylaxis, the Diagnosis and the Treatment of Malignant Hyperthermia

    • Principal Investigator
      FUJIOKA Yasuhiro
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      Hiroshima University
  •  Halothane induced Lipid perosidation and Hepatotoxicity

    • Principal Investigator
      FUJII Kohyu
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      Hiroshima University
  •  Phagocytic and Bacteriocidal Function of Polymorphnuclear Leuckocytes(PMNLs) in Surgical Patients.

    • Principal Investigator
      OSAFUMI YUGE
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      Hiroshima University

All 2024 2023

All Journal Article Presentation

  • [Journal Article] Effects of Remimazolam on Intracellular Calcium Dynamics in Myotubes Derived from Patients with Malignant Hyperthermia and Functional Analysis of Type 1 Ryanodine Receptor Gene Variants2023

    • Author(s)
      Miyoshi Hirotsugu、Otsuki Sachiko、Mukaida Keiko、Kido Kenshiro、Sumii Ayako、Ikeda Tsuyoshi、Noda Yuko、Yasuda Toshimichi、Narasaki Soshi、Kato Takahiro、Kamiya Satoshi、Horikawa Yousuke T.、Tsutsumi Yasuo M.
    • Journal Title

      Genes

      Volume: 14 Issue: 11 Pages: 2009-2009

    • DOI

      10.3390/genes14112009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09047, KAKENHI-PROJECT-23K08332, KAKENHI-PROJECT-21K08948, KAKENHI-PROJECT-22K16602
  • [Presentation] Genetic panel testing of malignant hyperthermia patients in Japan2024

    • Author(s)
      Ayako Sumii, Hirotsugu Miyoshi, Keiko Mukaida, Tsuyoshi Ikeda, Kenshiro Kido, Yuko Noda, Toshimichi Yasuda, Sachiko Otsuki, Rieko Kanzaki, Yasuo Tsutsumi
    • Organizer
      18th World Congress of Anaesthesiologists
    • Data Source
      KAKENHI-PROJECT-23K08332
  • [Presentation] 悪性高熱症原因遺伝子であるジヒドロピリジン受容体遺伝子の変異R174W機能解析2023

    • Author(s)
      向田 圭子、大月 幸子、野田 祐子、神崎 理英子、三好 寛二、堤 保夫
    • Organizer
      本麻酔科学会第70回学術集会
    • Data Source
      KAKENHI-PROJECT-23K08332
  • 1.  MICHI MORIO (80033950)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  FUJII Kohyu (60034021)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  堤 保夫 (90523499)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  YUGE Osafumi (40034128)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KIKUCHI Hirosato (40034029)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  三好 寛二 (50645364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  KAWAMOTO Masashi (40127642)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OOSAWA Yasuhiro (00263682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  AKITA Susumu (40175790)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  FUJIOKA Yasuhiro (00192310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KUBOTA Minoru (00221226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  石原 晋 (00106808)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  木下 博之 (00127515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  木下 博之 (60136083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  野田 祐子 (00790065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  村山 尚 (10230012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  近藤 隆志 (20711774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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