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YAMAZAKI Hitoshi  山崎 等

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… Alternative Names

山崎 等  ヤマザキ ヒトシ

YAMAZAKI Htioshi  山崎 等

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Researcher Number 20191273
Affiliation (Current) 2025: 北里大学, 北里大学メディカルセンター, 教授
Affiliation (based on the past Project Information) *help 2016: 北里大学, 北里大学メディカルセンター, 教授
2015: 北里大学, 医学部, 教授
2014: 北里大学, 医学部, 准教授
2005 – 2006: Tokai University, School of Medicine, Associate Professor, 医学部, 助教授
2004: 東海大学, 医学部, 講師 … More
2000 – 2002: 東海大学, 医学部, 講師
1994 – 1998: Tokai University School of Medicine Assistant Professor, 医学部, 講師
1990 – 1991: 東海大学, 医学部・病理学教室, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
Experimental pathology / Human pathology / Laboratory animal science / Experimental pathology / Laboratory animal science / Digestive surgery
Keywords
Principal Investigator
differential screening / lung cancer / adenocarcioma / ダイレクトシークエンス / BAC / AAH / ディファレンシャル ディスプレイ / 微小肺腺癌 / 腺癌 / 肺癌 … More
Except Principal Investigator
… More in vivo / molecular pathology / multidrug resistance / 分子病理学 / 抗癌剤多剤耐性 / S100A4 / NOG mouse / 悪性黒色腫 / 遠隔転移 / NOGマウス / 転移 / MRP gene / MDR1 gene / 多剤耐性克服 / MDR1遺伝子 / 肺癌 / リボザイム / Ribozyme / 上皮増殖因子受容体 / 神経膠腫 / Distant metastasis / DNA chip analysis / Malignant melanoma / Large intestinal cancer / Pancreatic cancer / DNAチップ解析 / 大腸癌 / 膵癌 / NK cell / Metastasis / Angiogenesis / Microenvironment / 多発性骨髄腫 / ADCC / ヒト癌 / マウスモデル / 間質蛋白分解酵素 / トロンボスポンジン / 遠隔転移抑制 / NK細胞 / 血管新生 / 微小環境 / mice model / ras oncogene / pancreatic cancer / gene modulation / RNA enzyme / ribozyme / 膵臓癌 / ras遺伝子 / 癌遺伝子 / 遺伝子発現制御 / 機能性核酸 / lung cancer / 抑制性癌遺伝子 / 免疫染色 / 肺扁平上皮癌 / 非定型的抗癌剤多剤耐性 / MRP / nm23 gene / metastasis / lung cancer xenograft / immune deficient mouse / 腫瘍Xenograft / NM23遺伝子 / 皮下移植 / VEGF / 移植Xenograft / 免疫不全動物 / expreimental therapy / transgenic mouse / reversal of MDR / blood brain barrier / brain tumor / 化学療法 / 膜能動輸送 / P糖蛋白質 / MDR / 治療実験 / トランスジェニックマウス / 血液脳関門 / 脳腫瘍 / acquired resistance / non-small cell lung cancer / RT-PCR / 肺癌Xenograft / 膜P糖蛋白質 / 非小細胞性肺癌 / MRP遺伝子 / Antisense RNA / Epidermal Growth Factor Receptor / Experimental Gene Therapy / Malignant glioma / in vitro転写 / ヒト腫瘍xenograft / 上皮増殖因子受容体遺伝子 / アンチセンスRNA / 遺伝子治療 / 悪性神経膠腫 / ヘリコバクターピロリ / 癌精巣抗原 / 早期胃癌 / メチル化 / Helicobacter pylori / KK-LC-1 / 癌/精巣抗原 / 胃癌 / Min-6 / Insulin / Transgenic / mice / Inducible System / Tetracyclin / 線維性腫瘍 / ポジショナルクローニング / 特異遺伝子 / 再発 / 難治性 / 繊維性腫瘍 / 良性腫瘍 / 遺伝子再構成 / 遺伝子増幅 / RTーPCR / コロニ-刺激因子 / サイトカイン / 造血刺激因子 / 高カルシウム血症 Less
  • Research Projects

    (14 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (11 People)
  •  The characteristics of a new tumor associated antigen, Kita-kyushu lung cancer antigen-1(KK-LC-1)

    • Principal Investigator
      Futawatari Nobue
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
      Kitasato University
  •  Development of in vivo experimental system for analyses of human cancer inductive microenvironment by using NOG mice

    • Principal Investigator
      UEYAMA Yoshito
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokai University
  •  Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/_<γ_c>^<null> (NOG) mice.

    • Principal Investigator
      NAKAMURA Masato
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  リボザイム誘導システムを具備する細胞・個体レベルの遺伝子発現調節実験系の開発

    • Principal Investigator
      水島 友子
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Central Institute for Experimental Animals
  •  Molecular cloning of the genes related to the early stage of the peripheral type of lung adenocarcinomasPrincipal Investigator

    • Principal Investigator
      YAMAZAKI Hitoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  Intracellular localization of multidrug resistance associated protein (MRP) and atypical multidrug resistance phenomenon in non-small cell lung cancer

    • Principal Investigator
      NAKAMURA Masato
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University
  •  Anti-oncogene hammerhead ribozymes (RNA enzymes) specifically inhibit oncogens in a mice model system.

    • Principal Investigator
      KIJIMA Hiroshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  難治性の繊維性良性腫瘍(デスモイド腫瘍)の再発を規定する特異的遺伝子の同定

    • Principal Investigator
      玉置 憲一
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Human pathology
    • Research Institution
      Tokai University
  •  Establishment of severe combined immune deficient mice introduced with human MDR1 geneinducted by murine endothelin promoter

    • Principal Investigator
      TAMAOKI Norikazu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  An experimental model for in vivo distant metastasis of human xenografts subcutaneously transplanted in imuune-deficient mice

    • Principal Investigator
      UEYAMA Yoshito
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokai University
  •  Molecular analysis of acquired multidurg resistance in non-small cell lung cancer

    • Principal Investigator
      NAKAMURA Masato
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University
  •  Experimental Model for Gene Therapy of Malignant Glioma

    • Principal Investigator
      UEYAMA Yoshito
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  上皮増殖因子受容体異常を指標とした膠細胞腫の新しい分子診断法の開発

    • Principal Investigator
      上山 義人
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokai University
  •  腫瘍の進展に伴う高カルシウム血症発現機序に於ける造血刺激因子の役割

    • Principal Investigator
      TAMAOKI Norikazu
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokai University

All 2017 2016 2015 2006 2005

All Journal Article Presentation

  • [Journal Article] Correlation Between Expression of Cancer/Testis Antigen KK-LC-1 and Helicobacter pylori Infection in Gastric Cancer2017

    • Author(s)
      T. Fukuyama, N. Futawatari, Y. Ichiki, A. Shida, T. Yamazaki, Y. Nishi, H. Nonoguchi, Y. Takahashi, H. Yamazaki, N. Kobayashi
    • Journal Title

      In vivo

      Volume: 31 Pages: 403-407

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670609
  • [Journal Article] Frequent High Expression of Kita-Kyushu Lung Cancer Antigen-1 (KK-LC-1) in Gastric Cancer2015

    • Author(s)
      Akiko Shida, Nobue Futawatari, Takashi Fukuyama, Yoshinobu Ichiki, Yoshihito Takahashi, Yatsushi Nishi, Noritada Kobayashi, Hitoshi Yamazaki, Masahiko Watanabe
    • Journal Title

      Anticancer Research

      Volume: 35 Pages: 3575-3580

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670609
  • [Journal Article] Poor outcome of patients with pulmonary adenocarcinoma showing decreased E-cadherin combined with increased S100A4 expression2006

    • Author(s)
      N.Miyazaki, Y.Abe, H.Yamazaki, M.Nakamura et al.
    • Journal Title

      International Journal of oncology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer2006

    • Author(s)
      T.Kamiya, T.Kawakami, H.Yamazaki, M.Nakamura et al.
    • Journal Title

      Oncology Reports 15

      Pages: 369-373

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] Poor outcome of patients with pulmonary adenocarcinoma showing decreased E-cadherin combined with increased S100A4 expression2006

    • Author(s)
      N.Miyazaki, Y.Abe, H.Yamazaki, M.Nakamura et al.
    • Journal Title

      International Journal of Oncology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer2006

    • Author(s)
      T.Kamiya T.Kawakami, H.Yamazaki, M.Nakamura et al.
    • Journal Title

      Oncology Reports 15

      Pages: 369-373

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] The preserved expression of neuropilin (NRP) 1 contributes to a better prognosis in colon cancer2006

    • Author(s)
      T.Kamiya T.kawakami, H.Yamazaki, M.Nakamura et al.
    • Journal Title

      Oncology Reports 15

      Pages: 369-373

    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] S100A4 expression with reduced E-cadherin expression predicts distant metastasis of human malignant melanoma cell lines in NOD/SCID/γc^<null>(NOG) mouse model2005

    • Author(s)
      N.Ikoma, H.Yamazaki, Y.Ohnishi, Y.Ueyama, M.Nakamaura et al.
    • Journal Title

      Oncology Reports 14

      Pages: 633-637

    • Data Source
      KAKENHI-PROJECT-16300137
  • [Journal Article] S100A4 expression with reduced E-cadherin expression predicts distant metastasis of human malignant melanoma cell lines in NOD/SCID/γc^<null>(NOG) mouse model2005

    • Author(s)
      N.Ikoma, H.Yamazaki, H.Suemizu, M.Nakamaura et al.
    • Journal Title

      Oncology Reports 14

      Pages: 633-637

    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] S100A4 expression with reduced E-cadherin expression predicts didtant metastasis of human malignant melamona cell lines in NOD/SCID/γc^<null>(NOG) mouse model2005

    • Author(s)
      N.Ikoma, H.Yamazaki, H.Suemizu, N.Nakamura et al.
    • Journal Title

      Oncology Reports 14

      Pages: 633-637

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] Cell binding isoforms of vascular endothelial growth factor-A (VEGF189) contribute to blood flow-distant metastasis of pulmonary adenocarcinoma2005

    • Author(s)
      M.Nishi, Y.Abe, H.Yamazaki, M.Nakamura et al.
    • Journal Title

      International Journal of Oncology 26

      Pages: 1517-1524

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] S100A4 expression with reduced E-cadherin expression predicts distant metastasis of human malignant melanoma cell lines in NOD/SCID/_<γ_c>^<null> (NOG) mouse model2005

    • Author(s)
      N.Ikoma, H.Yamazaki, H.Suemizu, M.Nakamura et al.
    • Journal Title

      Oncology Reports 14

      Pages: 633-637

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590325
  • [Journal Article] Aberrant expression of the gastric mucin MUC6 in human pulmonary adenocarcinoma xenografts2005

    • Author(s)
      A.Hamamoto, H.Yamazaki, Y.Ohnishi, Y.Ueyama, M.Nakamura et al.
    • Journal Title

      International Journal of Oncology 26

      Pages: 891-896

    • Data Source
      KAKENHI-PROJECT-16300137
  • [Presentation] 胃癌診断における癌特異的抗原KK-LC-1の有用性2016

    • Author(s)
      江間 玲, 福山 隆, 二渡 信江, 信太 昭子, 千野 慎一郎,和田 治, 久保 任史, 小野里 航, 近藤 康史, 高橋 禎人,池永 誠, 小林 憲忠, 山崎 等, 西 八嗣, 渡邊 昌彦
    • Organizer
      第116回日本外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-26670609
  • [Presentation] 胃癌におけるKK-LC-1高頻度発現の原因解明2016

    • Author(s)
      江間 玲, 二渡 信江, 福山 隆, 高橋 禎人, 山崎 等, 西 八嗣, 渡邊 昌彦
    • Organizer
      第71回日本消化器外科学会総会
    • Place of Presentation
      徳島
    • Year and Date
      2016-07-14
    • Data Source
      KAKENHI-PROJECT-26670609
  • [Presentation] 胃癌診断における癌特異的抗原KK-LC-1の有用性2015

    • Author(s)
      信太昭子、二渡信江、福山隆、横田光央、中本修司、小野里航、近藤康史、高橋禎人、池永誠、小林憲忠、山崎等、西八嗣
    • Organizer
      第115回 日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-18
    • Data Source
      KAKENHI-PROJECT-26670609
  • [Presentation] 胃癌における癌精巣抗原の発現と臨床病理学的検討について2015

    • Author(s)
      二渡信江、福山隆、横田光央、中本修司、信太昭子、小野里航、近藤康史、高橋禎人、池永誠、小林憲忠、山崎等、西八嗣
    • Organizer
      第115回 日本外科学会定期学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-04-18
    • Data Source
      KAKENHI-PROJECT-26670609
  • 1.  NAKAMURA Masato (00164335)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 9 results
  • 2.  UEYAMA Yoshito (30072408)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 2 results
  • 3.  TAMAOKI Norikazu (50055860)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  KIJIMA Hiroshi (90204859)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Futawatari Nobue (40306600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  OHNISHI Yasuyuki (70201382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  SUEMIZU Hiroshi (40332209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  島村 和男 (00119679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  水島 友子 (90311240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  福山 隆 (10462251)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 11.  高橋 禎人 (80245406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results

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