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SHINEHA Ryuzaburo  標葉 隆三郎

ORCIDConnect your ORCID iD *help
Researcher Number 20192106
External Links
Affiliation (based on the past Project Information) *help 2000: 東北大, 医学部附属病院, 講師
1999 – 2000: Tohoku University Hospital, Lecturer, 医学部・附属病院, 講師
1995 – 1998: School of Medicine hospital The Second Dept.of Surgery, Lecturer, 医学部, 講師
1987 – 1994: 東北大学, 医学部, 助手
1991: 東北大学, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Digestive surgery
Except Principal Investigator
General surgery / Digestive surgery
Keywords
Principal Investigator
IL-6 / 侵襲 / カテコールアミン / サイトカイン / CAPD / cytokine / stress / 微小透析法 / ステロイド / microdialysis … More / peritoneal lavage / salt solution / 生理的食塩水 / 腹腔洗浄 / 生理食塩水 / steroid / Meeylprednisolone / ストレスホルモン / マクロファージ / G-CSF / IL-8 / accumulation of genetic alterations. / p16 mutation in esophageal carcinoma / esophageal carcinogenesis / allelotype of the esophageal carcinoma / RCR-SSCP / 微小リンパ節転移 / 食道癌 / PCR-SSCP法 / MASA法 / p16 / p53 / visceral fatty tissue / lipolysis / Na-K flux / Na^+-K^+ flux / Glycerol代謝 / Glycerol 代謝 / NA^+-K^+ flux / glycerol metabolism / chatecholamines / Microdialysis / 手術侵襲 / 脳内カテコールアミン / グリセロール / 脂肪 … More
Except Principal Investigator
手術侵襲 / 食道癌 / サイトカイン / 安定同位体 / 肝移植 / GST / sialylation / 悪性度評価 / 転移能 / シアル酸 / シアリダーゼ / Gene therapy / 放射線被曝 / 甲状腺癌 / methylprednisolone / steroid / 微小透析法 / 自家骨髄移植 / aFGF / ミトコンドリア / hst-1 / EGFR / 顆粒白血球 / ホルモン変動 / Metastatic potential / Sialidase / Esophageal cancer / 遺伝子導入 / Liver metabolizing enzymes / surgical stress / 経腸栄養 / TPN / 肝薬物代謝酵素活性 / 肝薬物代謝酵素 / metastatic potential / colon 26 / B16 melanoma / sialidase / Colon26 / B16メラノーマ / rejection / dichloromethylene bisphosphonate / Liver transplantation / kupffer cell / macrophage / LE-Cl_2MDP / リポソーム包埋クロドロネート / クッパー細胞(Kc) / 拒絶反応 / ジクロロメチレンビスホスホネート / クッパー細胞 / マクロファージ / Hypothyroidism / Endemic goiter / Iodido deficieny / Marshall Islands / Oncogene / Bikini / Radiation effect / Thyroid tamor / 慢性甲状腺炎 / 甲状腺機能低下症 / ヨード欠乏性甲状腺腫 / ヨード欠乏 / マーシャル諸島 / がん遺伝子 / ビキニ事件 / 甲状腺腫瘍 / Antisense therapy / Laser device / Hepatocyte transplantation / Liver cirrhosis / 遺伝子治療 / レーザー / 胎児肝細胞 / アンチセンス法 / 遺伝子操作 / 肝細胞移植 / 肝硬変 / stress / cytokines / hormones / ステロイド投与 / k Flux / Na / Endotoxin / microdialysis / 13-Ctriolein / 侵襲 / Atomic Bomb Test / Ultrasound Image Scanning / Iodine Intake / Nodular Goiter / The Republic of Marshall Islands / Radiation Exposure / Thyroid Cancer / 核実験 / 超音波断層撮影 / ヨード摂取 / 結節性甲状腺腫 / マーシャル諸島共和国 / ischemia-reperfusion model / third space / non functional extracellular fluid / 非機能的細胞外液量 / オートラジオグラフィー / メチルブレドンゾロン(MP) / IL-8 / 全身オートラジオグラム / 14C-Inulin / 侵襲モデル / stress hormone / cytokine / biological response / 手術侵襲の転減 / 生体反応の制御 / 生体反応 / ATPアーゼ / 脂質過酸化障害 / viability / Viability / ATPase / 好中球 / 脂質過酸化 / フリーラジカル / 再潅流障害 / マクロファージのFc-αレセプター / 食道癌の根治手術 / マクロファージFc-γレセプター / GM-CSF / r-G-CSF / r-IL-III / 手術変動 / 代謝変動 / 遺伝子クローニング / Magnetic Separation System / 悪性化因子 / CSF / Midkine / amphiregulin / bFGF / 増殖因子 / PCR / 食道癌の自律増殖 / TE-9 / (ヒト食道癌細胞株)TE-1 / C8細胞 / MEE / 接着因子 / 血管内皮細胞 / 多核白血球 / 血管壁の粘弾性 / 超音波ドップラ- / 動脈硬化壁 / 硬化度の指標 / 移植血管 / 人正常血管 / 非侵襲的 / 粘弾性度 / 弾性度 / 超音波ドプラー / 低出力レ-ザ- / 疼痛緩和 / 微弱発光 / 生物フォトン / 生体刺戟 / 光照射 / 創傷治癒 / マイクロダイヤリシス / リポ蛋白リパ-ゼ / 間接熱量計 / 蛋白・エネルギ-代謝 / リポ蛋白リパーゼ / 間接熱量測定 / 蛋白・エネルギー代謝 / 極超微弱発光 / Primary graft nonfunction / 人工心肺 / 類洞内皮細胞 / フリ-ラジカル / 過酸化脂質 / primary graft nonfunction / 血清中毒性測定 / fura-2 / Myonephropathic Metabelic Syndrome / 顆粒球活性 / Furaー2 / 培養血管内皮細胞 / MNMS / GST-π / Nothern blot法 / Southern blot法 / erbB-2 / GSTーπ / 遺伝子増幅と予後 / cーmyc / hstー1 / erbBー2 / 甲状腺ホルモン / phosphorylase / 安静時エネルギ-消費量 / 脂質代謝回転 / 蛋白代謝回転 / 顆粒球エラマタ-ゼ / cyclic AMP / 白血球補体レセプタ- / 生体防御 Less
  • Research Projects

    (31 results)
  • Co-Researchers

    (50 People)
  •  Study of sialidase expression in melanoma cell line and esophageal cancers

    • Principal Investigator
      MIYAZAKI Shukichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU University
  •  手術侵襲下における、脂肪代謝の変動に関する研究Principal Investigator

    • Principal Investigator
      標葉 隆三郎
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  EFFECT OF DEPLETION OF KUPFFER CELLS AND MACROPHAGES ON ACUTE REJECTION OF LIVER TRANSPLANTATION

    • Principal Investigator
      DOI Hideyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  Development of new composition of peritoneal savage fluidsPrincipal Investigator

    • Principal Investigator
      SHINEHA Ryuzaburo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  Study of sialidase activity to evaluate malignant potential of carcinoma cells

    • Principal Investigator
      MIYAZAKI Syukichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  Liver drug metabolizing enzyme damages by nutrition and surgical stress

    • Principal Investigator
      SAYAMA Junzo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  転移能を規定する食道癌悪性化因子のクローニング

    • Principal Investigator
      赤石 隆
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Modulation of excessive responses by surgical stress using steroidsPrincipal Investigator

    • Principal Investigator
      SHINEHA Ryuzaburo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU University
  •  The thyroid disease study in the Republic of the Marshall Islands

    • Principal Investigator
      SATOMI Susumu
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tohoku University
  •  自家骨髄移植法の導入による食道癌外科治療体系の変革

    • Principal Investigator
      赤石 隆
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  The thyroid disease study in the Republic of the Marshall Islands

    • Principal Investigator
      NISHIHARA Tetsuro
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      TOHOKU UNIVERSITY
  •  Evaluation and regulation of excessive biological responses with major surgery

    • Principal Investigator
      NISHIHIRA Tetsuro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Gene therapy-for live cirrhosis by multiplicable hepatocyte and antisense of collagenase-mRNA

    • Principal Investigator
      OHKOHCHI Nobuhiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Micro-lymphonode Metastasis of Esophageal Carcinoma being impossible to detect by Conventional Pathological MethoPrincipal Investigator

    • Principal Investigator
      SHINEHA Ryuzaburo, 片山 正文
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Analysis of Non-functional Extra cellular Fluid Space in the Ischemic Reperfusion Injury Model

    • Principal Investigator
      HIRAKAWA Hisashi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  The comparison of lipolysis between the visceral and subcutaneous fatty tissue under the severe stress by in-situ microdialysis techniguePrincipal Investigator

    • Principal Investigator
      SHINEHA Ryuzaburo
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  食道癌に発現する増殖因子の検討-食道癌の増殖の特性と悪性度に関連して-

    • Principal Investigator
      片山 正文
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Evaluation and regulation of excessive biological responses with major surgery

    • Principal Investigator
      MORI Shozo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  食道癌の自律増殖に関する研究ーautocrine growth factorの研究

    • Principal Investigator
      片山 正文
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  移植肝障害発生機序の解明と新らしいviability判定法の検討(エネルギー産生能と脂質過酸化障害からの検討)

    • Principal Investigator
      大河内 信弘
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Continuous Analysis of metabolism of tissues by in vivo MicrodialysisPrincipal Investigator

    • Principal Investigator
      SHINEHA Ryuzaburo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  手術侵襲下における生体反応と蛋白・エネルギー基質代謝動態に関する研究

    • Principal Investigator
      森 昌造
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  光照射と生体反応に関する研究ー特に低出カレーザーによる生体刺戟と創傷治癒促進現象の解明

    • Principal Investigator
      田口 喜雄
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  動脈の粘弾性的性質解析のための無侵襲計測法の臨床的・基礎的研究

    • Principal Investigator
      大熊 恒郎
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  手術侵襲下の微小循環系における血管内皮ー多核白血球相互反応

    • Principal Investigator
      西平 哲郎
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  肝移植におけるグラフト肝機能不全の発生機序の解明とその予防法の検討(障害発生機序からみた摘出法,保存法ならびに肝viability判定法の検討)

    • Principal Investigator
      OHKOICHI Nobuhiro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  生体防御機構を中心とした侵襲下における蛋白・エネルギ-代謝動態に関する研究

    • Principal Investigator
      MORI Shozo
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  ヒト食道癌の悪性度評価に関する研究ー特に癌遺伝子,遺伝子産物の検索

    • Principal Investigator
      西平 哲郎
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Revascularization Syndromeの機構解明ー培養血管内皮細胞,心筋細胞に対する細胞毒性による解明ー

    • Principal Investigator
      大熊 恒郎
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  自家骨髄移植を用いた新しい食道癌集学的外科治療法確立に関する研究-特にrecombinantヒトIL-III及びrecombinantヒトGM-CSFを用いて-

    • Principal Investigator
      平山 克
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  非放射性同位体による動的解析を中心とした侵襲下の代謝変動に関する研究

    • Principal Investigator
      森 昌造
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  • 1.  NISHIHIRA Tetsuro (50101142)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 2.  OHKOICHI Nobuhiro (40213673)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  DOI Hirotaka (90188839)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 4.  HIRAYAMA Katsu (20181191)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  MIYAZAKI Shukichi (50282075)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 6.  SATOMI Susumu (00154120)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  志賀 清人 (10187338)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 8.  TAGUCHI Yoshio (70004885)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 9.  AKAISHI Takashi (60191847)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 10.  SAYAMA Junzo (60292322)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 11.  片山 正文 (00177411)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 12.  MORI Shozo (70004877)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 13.  KATO Hirotaka (00240656)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 14.  KUROKAWA Yoshimochi (80215087)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 15.  TERASAWA Takayuki (10292319)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 16.  TAMURA M (20124604)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  ORII Takashi (20282048)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  HIRAKAWA Hisashi (10250763)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  佐藤 俊一 (30162431)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  FUJIMORI Keisei (50238622)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  MIYATA Goh (60282076)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  KIMURA Noriko (80142975)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  ANDO Kenjiro (40261614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  立木 蔚 (90006065)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  大熊 恒郎 (50160453)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  大内 憲明 (90203710)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  高野 亮 (30271935)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  北村 道彦 (10153131)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  桜田 正寿 (40292320)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  菅原 弘光 (80302123)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  SATAKE Masahiro (70147370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  CHUBACHI Seiji (90302108)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  SEKIGUCHI Satoshi (20312580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  ITOH Tsunetoshi (90004746)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  SUGAWARA Koh (30323025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  三浦 俊治 (50209714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  鈴木 康男 (00004573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  赤石 隆 (40200331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  稲場 文男 (90006213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  諸星 保憲 (60239712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  横堀 寿光 (00124636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  山本 雅之 (50166823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  小熊 司郎 (00194522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  原田 雄功 (90292317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  SIMON S.L.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  TROTT K.R
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  TROTT KーR
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  BECHTNER G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  張 徳恒
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  知久 一雄
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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