Sai Kimie 佐井君江

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SAI KIMIE 佐井君江

SAI Kimie 佐井君江

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Researcher Number	20195960
Other IDs
Affiliation (Current)	2022: 国立医薬品食品衛生研究所, 医薬安全科学部, 室長
Affiliation (based on the past Project Information) *help	2013 – 2021: 国立医薬品食品衛生研究所, 医薬安全科学部, 室長 2010 – 2011: 国立医薬品食品衛生研究所, 医薬安全科学部, 室長 2008 – 2009: 国立医薬品食品衛生研究所, 機能生化学部, 主任研究官 2000: National Institute of Health Sciences, Cell & Molecl. Tox. Div., Scientist, 毒性部, 主任研究員 1998 – 1999: National Institute of Health Sciences Div.of Cellular and Molecular Toxicology S, 毒性部, 主任研究官 1997: 国立医薬食品衛生研究所, 毒性部, 研究員 1996: 国立衛生試験所, 毒性部, 研究員
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Experimental pathology / Applied pharmacology / 広領域
Keywords	Principal Investigator オーダーメード医療 / α-1-酸性糖蛋白 / 薬剤反応性 / 遺伝子多型 / ハプロタイプ / ゲノム / 臨床 / 薬理学 / 抗がん剤 / 遺伝子 … More / 医療情報データベース / 薬物間相互作用 / 免疫バイオ医薬品 / スタチン / 免疫関連バイオ医薬品 / データベース / 重篤副作用 / リスク因子 / 免疫修飾因子 / 医薬品情報 / バイオシミラー / リアルワールドデータ / 抗TNFα抗体 / 副作用報告データベース / ナショナルデータベース / 臨床的同等性 … More Except Principal Investigator p53 / ペンタクロロフェノール / ギャップ結合細胞間連絡 / アポトーシス / gap junction / apoptosis / 薬剤反応性 / ゲノム / 薬理学 / 薬物トランスポーター / 転写因子 / グノム / 胚幹細胞 / 発生傷害 / 遺伝子突然変異 / 分化 / 突然変異検出系 / Embryonic stem cell / developmental toxicity / gene mutation / ギャップ結合細胞間コミュニケーション / pentachlorohenol / 発がんプロモーター / コネクシン / 造血幹細胞 / Gap junction(細胞間連絡) / promotion / connexin / pentachlorophenol / hemopoietic stem cell Less

リアルワールドデータを用いたバイオシミラーの臨床的同等性評価と影響因子の分析Principal Investigator
- Principal Investigator
  
  佐井君江
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  National Institute of Health Sciences
Identification and evaluation of risk factors for severe immune-mediated adverse drug reactions using Big DataPrincipal Investigator
- Principal Investigator
  
  SAI Kimie
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
Evaluation of interaction between biotechnology-based drug and chemical drug using medical information databasesPrincipal Investigator
- Principal Investigator
  
  SAI KIMIE
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
Association of genotypes for drug-binding protein with anti-cancer drug responsesPrincipal Investigator
- Principal Investigator
  
  SAI Kimie
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  National Institute of Health Sciences
マイクロRNAによる薬物トランスポーターの発現制御と遺伝子多型影響の解明
- Principal Investigator
  
  SAITO Yoshiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Blocks of cell communication and apoptosis in carcinogenesis
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
p53 null mice and chemical oncogenesis for promotion study
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
Construction of mouse embryonic stem cells for the detection of gene mutation
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  National Institute of Health Sciences

All 2020 2018 2017 2016 2011 2010 2009

All Journal Article Presentation

[Journal Article] Association between infection and severe drug adverse reactions: an analysis using data from the Japanese Adverse Drug Event Report database2017
- Author(s)
  Imatoh T, Sai K, Fukazawa C, Hinomura Y, Nakamura R, Okamoto-Uchida Y, Segawa K, Saito Y
- Journal Title
  
  European Journal of Clinical Pharmacology
  
  Volume: 73 Pages: 1643-1653
- DOI
  10.1007/s00228-017-2320-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08433, KAKENHI-PROJECT-17K08482
[Journal Article] Effect of Infectious Diseases on the Pathogenesis of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis2017
- Author(s)
  Okamoto-Uchida Y, Nakamura R, Sai K, Imatoh T, Matsunaga K, Aihara M, Saito Y.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 40 Issue: 9 Pages: 1576-1580
- DOI
  10.1248/bpb.b17-00207
- NAID
  130006038757
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08433, KAKENHI-PROJECT-17K08482
[Journal Article] Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients2011
- Author(s)
  Katori N, Sai K, Saito Y, Fukushima-Uesaka H, Kurose K,(fifteen other co-authors)
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 100 Pages: 4546-4559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] Different Safety Reporting Profiles Of Infliximab Biosimilar From Originator : Comparison Among Countries2020
- Author(s)
  Kimie Sai, Yoshiko Aoki, Yoshiro Saito
- Organizer
  36th International Conference on Pharmacoepidemiology & Therapeutic Risk Management
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07210
[Presentation] 重症薬疹に関するゲノムバイオマーカー探索研究の進捗と今後の課題2018
- Author(s)
  中村亮介, 今任拓也, 佐井君江, JSAR Research Group, 斎藤嘉朗
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-16K08433
[Presentation] JADERを用いた感染症と重篤副作用との関連に関する薬剤疫学研究：薬効別解析2017
- Author(s)
  今任拓也, 佐井君江, 深澤ちさと, 日野村靖, 瀬川勝智, 斎藤嘉朗
- Organizer
  第3回次世代を担う若手のためのレギュラトリーサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-16K08433
[Presentation] Effects of infection on incidence/severity of SJS/TEN and myopathy in Japanese cases analyzed by voluntary case reports2016
- Author(s)
  Ryosuke Nakamura, Kimie Sai, Takuya Imatoh, Yoshimi Okamoto-Uchida, Koji Kajinami, Kayoko Matsunaga, Michiko Aihara, Yoshiro Saito
- Organizer
  Drug Hypersensitivity Meeting 2016
- Place of Presentation
  Malaga (Spain)
- Year and Date
  2016-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08433
[Presentation] スティーブンス・ジョンソン症候群／中毒性表皮壊死症における感染症併発の影響2016
- Author(s)
  岡本(内田) 好海, 中村亮介, 佐井君江, 今任拓也, 松永佳代子, 相原道子, 斎藤嘉朗
- Organizer
  第２回次世代を担う若手のためのレギュラトリーサイエンスフォーラム
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K08433
[Presentation] Assessment of impact of infection on drug-induced severe cutaneous adverse reactions and rhabdomyolysis using the Japanese Adverse Drug Event Report database2016
- Author(s)
  Kimie Sai, Takuya Imatoh, Ryosuke Nakamura, Chisato Fukazawa, Yasushi Hinomura, Yoshiro Saito
- Organizer
  Drug Hypersensitivity Meeting 2016
- Place of Presentation
  Malaga (Spain)
- Year and Date
  2016-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08433
[Presentation] スティーブンス・ジョンソン症候群／中毒性表皮壊死症における感染症併発の影響2016
- Author(s)
  岡本(内田) 好海, 中村亮介, 佐井君江, 今任拓也, 松永佳代子, 相原道子, 斎藤嘉朗
- Organizer
  第23回日本免疫毒性学会学術年会
- Place of Presentation
  北九州国際会議場(福岡県・北九州市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K08433
[Presentation] パクリタキセル投与患者におけるα-1-acid glycoproteinと遺伝子多型、薬物動態および患者背景因子の関連性2011
- Author(s)
  香取典子、佐井君江、斎藤嘉朗、福島(上坂)浩美、黒瀬光一(他12名)
- Organizer
  日本薬学会第131年回
- Place of Presentation
  ツインメッセ静岡(静岡)
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] パクリタキセル投与患者におけるα1-acid glycoproteinと遺伝子多型、薬物動態および患者背景因子の関連性2011
- Author(s)
  香取典子、佐井君江、斎藤嘉朗, 他14名
- Organizer
  日本薬学会第131年回
- Place of Presentation
  ツインメッセ静岡(静岡)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] 日本人癌患者のORM遺伝子多型による血中α1酸性糖蛋白レベルへの影響2010
- Author(s)
  香取典子、佐井君江、斎藤嘉朗, 他14名
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉)
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] 日本人癌患者のORM遺伝子多型による血中α-1-酸性糖蛋白レベルへの影響2010
- Author(s)
  香取典子、佐井君江、斎藤嘉朗、福島(上坂)浩美、黒瀬光一、(他12名)
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  大宮ソニックシティ(埼玉)
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] Genetic polymorphisms of ORM1 and ORM2 genes encoding al-acid glycoproteins in a Japanese population2009
- Author(s)
  香取典子、斎藤嘉朗、佐井君江, (他15名)
- Organizer
  第16回ISSX北米大会
- Place of Presentation
  ボルチモアマリオット(ボルチモア、米国)
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21590191
[Presentation] Haplotype structure of genes encoding α1-acid glycoprotein in a Japanese population2009
- Author(s)
  香取典子、斎藤嘉朗、佐井君江, (他15名)
- Organizer
  第24回日本薬物動態学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21590191

1. INOUE Tohru (50100110)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. SAITO Yoshiro (50215571)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. HORI KATSUHITO (20436786)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HIRABAYASHI Yoko (30291115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KANNO Jun (90186172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TROSKO James E.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KATORI Noriko (60142121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. KUROSE Koichi (30280754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. KAWAKAMI JUN-ICHI (50272539)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAGA Yumiko (50221271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAGI Atsuya (00179417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HASEGAWA Ryuichi (50112496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 石田誠一 (10270505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤本成明 (40243612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 梅村隆志 (50185071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 能美健彦 (30150890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 今任拓也 (20368989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
18. 佐藤嗣道 (50305950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KANG Kyung-sun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TROSKOJAMES ジェームス・イー・

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 岡本好海

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sai Kimie 佐井 君江

SAI KIMIE 佐井 君江

SAI Kimie 佐井 君江

Research Projects

Research Products

Co-Researchers

リアルワールドデータを用いたバイオシミラーの臨床的同等性評価と影響因子の分析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and evaluation of risk factors for severe immune-mediated adverse drug reactions using Big DataPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of interaction between biotechnology-based drug and chemical drug using medical information databasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association of genotypes for drug-binding protein with anti-cancer drug responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マイクロRNAによる薬物トランスポーターの発現制御と遺伝子多型影響の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Blocks of cell communication and apoptosis in carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

p53 null mice and chemical oncogenesis for promotion study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of mouse embryonic stem cells for the detection of gene mutation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association between infection and severe drug adverse reactions: an analysis using data from the Japanese Adverse Drug Event Report database2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Infectious Diseases on the Pathogenesis of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Genetic variations of orosomucoid genes associated with serum alpha-1-acid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer patients2011

Author(s)

Journal Title

Data Source

[Presentation] Different Safety Reporting Profiles Of Infliximab Biosimilar From Originator : Comparison Among Countries2020

Author(s)

Organizer

Data Source

[Presentation] 重症薬疹に関するゲノムバイオマーカー探索研究の進捗と今後の課題2018

Author(s)

Organizer

Data Source

[Presentation] JADERを用いた感染症と重篤副作用との関連に関する薬剤疫学研究：薬効別解析2017

Sai Kimie 佐井君江

SAI KIMIE 佐井君江

SAI Kimie 佐井君江