Ishida Seiichi 石田誠一

… Alternative Names

Researcher Number	10270505
Other IDs
Affiliation (Current)	2022: 崇城大学, 生物生命学部, 教授 2022: 国立医薬品食品衛生研究所, 薬理部, 客員研究員
Affiliation (based on the past Project Information) *help	2022: 崇城大学, その他部局等, 教授 2020: 崇城大学, 生物生命学部, 教授 2011 – 2016: 国立医薬品食品衛生研究所, 薬理部, 室長 2013: 国立医薬品食品衛生研究所, 薬理部第三室, 室長 2007 – 2009: National Institute of Health Sciences, 薬理部, 室長 2006: 国立医薬品食品衛生研究所, 薬理部, 主任研究官 1996: 癌研究会癌研究所, 遺伝子, 研究員
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 90110:Biomedical engineering-related Except Principal Investigator Applied pharmacology / Biofunction/Bioprocess / General pharmacology / Biofunction/Bioprocess / Basic Section 27040:Biofunction and bioprocess engineering-related
Keywords	Principal Investigator 遺伝子コピー数多型 / CNV / 遺伝子多型 / 薬物動態関連遺伝子 / gene dosage effect / 網羅的解析 / GeneChip / 薬剤反応性 / ヒトゲノム / コピー数多型 … More Except Principal Investigator … More

肝星細胞の三次元培養による脂肪肝炎治療薬の新規スクリーニング系の開発Principal Investigator
- Principal Investigator
  
  石田誠一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Sojo University
シリカ繊維三次元培養担体によるがん細胞薬剤耐性の再現と新規スクリーニング系の構築
- Principal Investigator
  
  松下琢
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Sojo University
Studies on the evaluation method for chemical compound toxicity to human hepatocytes by using hollow fiber type three dimensional culture module
- Principal Investigator
  
  MATSUSHITA Taku
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Sojo University
Expression of drug resisitance phenomena of cancer cells by 3D-culture and its application to development of new assay system for anti-cancer drugs
- Principal Investigator
  
  MATSUSHITA Taku
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Sojo University
Proliferation of breast cancer stem cells via NO/cGMP signaling pathway
- Principal Investigator
  
  KANDA Yasunari
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  National Institute of Health Sciences
マイクロRNAによる薬物トランスポーターの発現制御と遺伝子多型影響の解明
- Principal Investigator
  
  斎藤嘉朗
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Development of the Analytical Methods for the Evaluation of Copy Number Variations of Drug Metabolizing Enzyme Related Genes in Japanese PopulationPrincipal Investigator
- Principal Investigator
  
  ISHIDA Seiichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  National Institute of Health Sciences
p53癌抑制遺伝子によるヒト発がん抑制の分子機構
- Principal Investigator
  
  土田信夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University

All 2021 2020 2016 2015 2014 2013 2007 Other

All Journal Article Presentation Book

[Book] How DNA microarray technology contributes to the retinoid evaluations. In "Vitamin A : New Research" (Ed. Lossing IT.)2007
- Author(s)
  Ishida S, Tanabe H, Shinozaki Y, Koyano S, Kagechika H, Shudo K, Ozawa S, Sawada JI, Ohno Y, Inoue K.
- Publisher
  Nova Scientific Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-18590545
[Journal Article] Development of a new culture vessel using hydrogen-rich gelatin for evaluation of hydrogen gas effect on cellular toxicity2020
- Author(s)
  K. Inamura , A. Shiraki , K. Inoue , R. Jinno , Y. Komizu , T. Takeda , S. Ishida , T. Matsushita
- Journal Title
  
  Alternatives to Animal Testing and Experimentation
  
  Volume: 25 Pages: 41-47
- NAID
  130008076119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05241
[Journal Article] Upregulations of metallothionein gene expressions and tolerance to heavy metal toxicity by three dimensional cultivation of HepG2 cells on VECELL 3-D inserts2016
- Author(s)
  T. Kubo, Y. Kuroda, S. Horiuchi, SR. Kim, Y. Sekino, S. Ishida
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: 41 Issue: 1 Pages: 147-153
- DOI
  10.2131/jts.41.147
- NAID
  130005119790
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26420804
[Journal Article] Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells2014
- Author(s)
  H. Dubois-Pot-Schneider, K. Fekir, C. Coulouarn,D. Glaise, C. Aninat, K. Jarnouen, R. Le Guevel, T. Kubo, S. Ishida, F. Morel, A. Corlu
- Journal Title
  
  Hepatology
  
  Volume: 60 Pages: 2077-2090
- DOI
  10.1002/hep.27353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26420804
[Journal Article] Comparative metabolome analysis of cultured fetal and adult hepatocytes in humans2014
- Author(s)
  S.-R. Kim, T. Kubo, Y. Kuroda, M. Hojyo, T. Matsuo, A. Miyajima, M. Usami, Y. Sekino, T. Matsushita, S. Ishida
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: 40 Issue: 5 Pages: 438-442
- DOI
  10.2131/jts.39.717
- NAID
  130004690958
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26420804
[Journal Article] Developing and standardizing experimental protocols using human iPS-derived cells to predict adverse drug reactions in pre-clinical safety studies2013
- Author(s)
  Sekino Y, Sato K, Kanda Y, Ishida S.
- Journal Title
  
  Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku
  
  Volume: 131 Pages: 25-34
- NAID
  40019879865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590322
[Journal Article] Involvement of decreased glutamate receptor subunit GluR2 expression in lead-induced neuronal cell death2013
- Author(s)
  Ishida K., Kotake Y., Miyara M., Aoki K., Sanoh S., Kanda Y., Ohta S.
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: 38 Issue: 3 Pages: 513-21
- DOI
  10.2131/jts.38.513
- NAID
  10031158917
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590322
[Presentation] 3次元培養担体Cellbedを用いた肝細胞の胆汁排泄機能の再構築に関する研究2021
- Author(s)
  親富祖亮太、坂田望、古水雄志、岩佐卓哉、佐々木皓平、小島理恵、川部雅章、石田誠一、松下琢
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K05241
[Presentation] ハイブリッドリポソームの乳がん幹細胞に対する増殖抑制効果2021
- Author(s)
  角祐里奈、陳野莉子、古水雄志、松本陽子、松下琢、石田誠一
- Organizer
  第20回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K05241
[Presentation] 三次元培養担体を用いた毛細胆管の再構築による胆汁排泄機能を備えた肝毒性評価法2021
- Author(s)
  親富祖亮太、坂田望、古水雄志、岩佐卓哉、佐々木皓平、小島理恵、川部雅章、石田誠一、松下琢
- Organizer
  シンポジウム【細胞アッセイ技術の現状と将来】
- Data Source
  KAKENHI-PROJECT-20K05241
[Presentation] 新規ナノ粒子を用いた腫瘍原性肝幹細胞の排除機構に関する研究2020
- Author(s)
  陳野莉子、古水雄志、松本陽子、松下琢、石田誠一
- Organizer
  第33回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-20K05241
[Presentation] 三次元培養担体 Cellbed における肝細胞を用いた胆汁排泄機能の再構築に関する研究2020
- Author(s)
  親富祖亮太、坂田望、古水雄志、岩佐卓哉、佐々木皓平、小島理恵、川部雅章、石田誠一、松下琢
- Organizer
  第33回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-20K05241
[Presentation] シリカ繊維からなる三次元培養足場を用いた薬剤耐性克服現象の in vitro 評価2020
- Author(s)
  古水雄志、佐々木皓平、石田誠一、松下琢
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K05241
[Presentation] 胎児肝細胞及び成人肝細胞のメタボローム解析と化学物質毒性発現の比較解析（第三報）2016
- Author(s)
  白木明日香, 市川雄大, 稲村恒亮, 水民敬浩, 古水雄志, 石田誠一, 金秀良, 関野祐子, 松下琢
- Organizer
  第29回日本動物実験代替法学会
- Place of Presentation
  九州大学百年講堂福岡県福岡市
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-26420804
[Presentation] 胎児肝細胞及び成人肝細胞のメタボローム解析と化学物質毒性発現の比較解析（第二報）2015
- Author(s)
  市川雄大、松下琢、石井貴晃、古水雄志、金　秀良、石田誠一、宮島敦子、関野祐子
- Organizer
  日本動物実験代替法学会第28回大会
- Place of Presentation
  ワークピア横浜（神奈川県横浜市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26420804
[Presentation] ヒト胎児および成人肝細胞のメタボローム解析による基礎代謝機能と関連する遺伝子発現の比較解析2014
- Author(s)
  金秀良、久保崇、黒田幸恵、北条麻紀、宮島敦子、松下琢、関野祐子、石田誠一
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学（東京都町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-26420804
[Presentation] Comparative analysis of human fetal hepatocytes and adult hepatocytes by metabolomics and toxicity test2013
- Author(s)
  S.Ishida
- Organizer
  日本薬物動態学会第28回大会
- Place of Presentation
  東京都江戸川区タワーホール船堀
- Year and Date
  2013-10-10
- Data Source
  KAKENHI-PROJECT-23560951
[Presentation] Analysis of Copy Number Variations (CNVs) of Drug Metabolizing Enzyme Related Genes in Japanese2007
- Author(s)
  Ishida S, Tanabe H, Sawada JI, Ozawa S, Nakazawa K.
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-18590545
[Presentation] 胎児及び成人肝細胞のメタボロームと化学物質毒性発現の比較解析
- Author(s)
  松下琢, 石井貴晃, 市川雄大, 金秀良, 石田誠一, 宮島敦子, 関野祐子
- Organizer
  日本組織培養学会第 87 回大会
- Place of Presentation
  星陵会館（東京都千代田区）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26420804
[Presentation] Comparative analysis of human fetal hepatocytes and adult hepatocytes by metabolomics and toxicity test
- Author(s)
  S. Ishida, S-R. Kim, T. Kubo, Y. Kuroda, M. Hojyo, A. Miyajima, T. Matsushita, Y. Sekino
- Organizer
  日本薬物動態学会第28回大会
- Place of Presentation
  東京都江戸川区タワーホール船堀
- Data Source
  KAKENHI-PROJECT-23560951
[Presentation] 胎児及び成人肝細胞のメタボロームと化学物質毒性発現の比較解析
- Author(s)
  市川雄大、石井貴晃、古水雄志、松下琢、金秀良、石田誠一、宮島敦子、関野裕子
- Organizer
  日本動物実験代替法学会　第29回大会
- Place of Presentation
  横浜国立大学（神奈川県横浜市）
- Year and Date
  2014-12-05 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26420804
[Presentation] ヒト胎児肝細胞と成人肝細胞における基礎代謝機能と関連する遺伝子発現の比較解析
- Author(s)
  石田誠一、金秀良、久保崇、黒田幸恵、北条麻紀、宮島敦子、松下琢、関野祐子
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-26420804

1. MATSUSHITA Taku (10209538)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. OZAWA Shogo (20185581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TANABE Hideyuki (50261178)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 古水雄志 (80735829)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. MATSUMOTO Yoko (00133562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KANDA Yasunari (70510387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 土田信夫 (60089951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山下利春 (50167706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋玲 (60144565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山泉克 (70107093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 横田淳 (10191503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 斎藤嘉朗 (50215571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐井君江 (20195960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小沢正吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Ishida Seiichi 石田 誠一

石田 誠一 イシダ セイイチ

ISHIDA Seiichi 石田 誠一

Research Projects

Research Products

Co-Researchers

肝星細胞の三次元培養による脂肪肝炎治療薬の新規スクリーニング系の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シリカ繊維三次元培養担体によるがん細胞薬剤耐性の再現と新規スクリーニング系の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on the evaluation method for chemical compound toxicity to human hepatocytes by using hollow fiber type three dimensional culture module

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of drug resisitance phenomena of cancer cells by 3D-culture and its application to development of new assay system for anti-cancer drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proliferation of breast cancer stem cells via NO/cGMP signaling pathway

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マイクロRNAによる薬物トランスポーターの発現制御と遺伝子多型影響の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the Analytical Methods for the Evaluation of Copy Number Variations of Drug Metabolizing Enzyme Related Genes in Japanese PopulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

p53癌抑制遺伝子によるヒト発がん抑制の分子機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] How DNA microarray technology contributes to the retinoid evaluations. In "Vitamin A : New Research" (Ed. Lossing IT.)2007

Author(s)

Publisher

Data Source

[Journal Article] Development of a new culture vessel using hydrogen-rich gelatin for evaluation of hydrogen gas effect on cellular toxicity2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Upregulations of metallothionein gene expressions and tolerance to heavy metal toxicity by three dimensional cultivation of HepG2 cells on VECELL 3-D inserts2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparative metabolome analysis of cultured fetal and adult hepatocytes in humans2014

Author(s)

Journal Title

DOI

NAID

Ishida Seiichi 石田誠一

石田誠一イシダセイイチ

ISHIDA Seiichi 石田誠一