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Shinkai Yoichi  眞貝 洋一

… Alternative Names

SHINKAI Yoichi  眞貝 洋一

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Researcher Number 20211972
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6051-2484
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 開拓研究所, 主任研究員
Affiliation (based on the past Project Information) *help 2018 – 2025: 国立研究開発法人理化学研究所, 開拓研究本部, 主任研究員
2015 – 2017: 国立研究開発法人理化学研究所, 眞貝細胞記憶研究室, 主任研究員
2015: 理化学研究所, 眞貝細胞記憶研究室, 主任研究員
2011 – 2014: 独立行政法人理化学研究所, 眞貝細胞記憶研究室, 主任研究員
2012: 理化学研究所, 主任研究員 … More
2008 – 2010: Kyoto University, ウイルス研究所, 教授
2003 – 2005: Kyoto University, Institute for Virus Research, Professor, ウイルス研究所, 教授
1999 – 2002: 京都大学, ウイルス研究所, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Transformative Research Areas, Section (III) / Biological Sciences / 生物資源科学 / Obstetrics and gynecology / Genome biology / Medical genome science / Genome biology
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related … More / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Metabolomics / Functional biochemistry / Obstetrics and gynecology / Molecular biology / Biological Sciences Less
Keywords
Principal Investigator
エピジェネティクス / クロマチン / 転写抑制 / epigenetics / BSE / OGP / ノックアウト / ES細胞 / ヒストンメチル化 / 内在性レトロウイルス … More / 染色体 / テロメラーゼ / テロメア / トランスジェニックマウス / ノックアウトマウス / ヘテロクロマチン / histone methylation / heterochromatin / CRISPR/CAS9 / DNAメチル化 / 核内コンパートメント / クロマチンドメイン / クロマチンリモデリング / 3Dゲノム構造 / 生化学 / GENE TARGETING / CATTLE / PRION / クローニング / 遺伝子ターゲティング / 牛 / プリオン / chromosomal instability / DNA rep air / cell cycle / TRF 1 / telomere binding protein / telomerase / telomere / 不死化 / 老化 / テロメアーゼ / DNA障害チェック機構 / 染色体の安定性 / 細胞増殖 / TIN2 / TRF2 / 染色体の不安定性 / DNA修復 / 細胞周期 / TRF1 / テロメア結合因子 / mammal / fertilization / transgenic mouse / knockout mouse / reproductive biology / 哺乳類 / 受精 / 生殖生物学 / ノックダウン / スクリーニング / CRISPR-Cas9 / 遺伝子ノックアウト / 発現制御 / H3K9メチル化 / 網羅的KOスクリーニング / SETDB1 / レトロエレメント / CRISPR/Cas9 / ESET/SETDB1 / iPS細胞 / ヒトES細胞 / SETDB1/ESET / ヒト / ヒストンリジンメチル化酵素 / 抗体 / プロテオミクス / リジンメチル化 / タンパク質翻訳後修飾 / 脱メチル化 / 転写制御 / 内在性転移因子 / メチル化 / ヒストン / 生殖細胞 / ジーンターゲティング / ALT機構 / 組み換え修復 / RAG2 / RAG1 / エンハンサー / 対立形質排除 / 抗原レセプター … More
Except Principal Investigator
エピゲノム / G9a / SWI / SNF / 受精 / ヒストンメチル化 / 肥満 / 複合体 / 転写 / ヒストン / 転写調節 / 細胞分裂 / ヒストン修飾 / 心筋再生 / トランスポゾン / CRISPR-Cas9システム / 遺伝子欠損ハムスター / Ovgp1 / ゴールデン・ハムスター / 初期胚発育 / OVGP1 / ゴールデンハムスター / 初期発生 / 初期胚発生 / 着床 / 遺伝子編集 / ハムスター / 卵管 / 哺乳類 / インスリン抵抗性 / ピストン修飾酵素 / 脂肪細胞分化 / ヒストン修飾酵素 / メタボリックシンドローム / histone methylation / polycomb / complex / transcription / epigenetics / chromatin / ポリコーム / エピジェネティックス / クロマチン / knock-out mouse / transgenic mouse / oviduct-specific glycoprotein / fertilization / female reproductive tract / プロモーター / エストロゲン / ノックアウトマウス / トランスジェニックマウス / 卵管特異糖タンパク質 / 雌性生殖管 / ChIP / 糖脂質代謝 / 代謝 / Jhdm2a / H3K9 / エビゲノム / RNAシークエンス / ChIPシークエンス / Jmjdla / 糖脂質代謝調節 / Jmjd1a / ヒストン脱メチル化酵素 / 抑制 / DNAメチル化 / メチル化 / エピジェネティクス Less
  • Research Projects

    (20 results)
  • Research Products

    (177 results)
  • Co-Researchers

    (36 People)
  •  機動性ゲノムの認識機構の実体と種特異的応答の解明Principal Investigator

    • Principal Investigator
      眞貝 洋一
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Institute of Physical and Chemical Research
  •  Deciphering of the transposable elements enhancing cardiac myocyte proliferation to overcome heart failure

    • Principal Investigator
      小山 恭平
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Asahikawa Medical College
  •  Elucidation of molecular mechanism of heterochromatin formation and maintenancePrincipal Investigator

    • Principal Investigator
      眞貝 洋一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  Dynamics of chromatin potential associating with cellular differentiation and its molecular mechanismPrincipal Investigator

    • Principal Investigator
      Shinkai Yoichi
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  Comprehensive understanding of H3K9me-mediated transcriptional silencingPrincipal Investigator

    • Principal Investigator
      Shinkai Yoichi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  Oviduct as the site of fertilization and early embryonic development: Verification of its physiological functions using genetically engineering hamster model for clinical application

    • Principal Investigator
      ARAKI Yoshihiko
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Nihon University
      Juntendo University
  •  Molecular mechanism of H3K9me-mediated transcriptional silencingPrincipal Investigator

    • Principal Investigator
      Shinkai Yoichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Genome biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Elucidation of transcriptional repression mechanism for human endogenous retrovirusPrincipal Investigator

    • Principal Investigator
      SHINKAI Yoichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      The Institute of Physical and Chemical Research
  •  蛋白質リジンメチル化のプロテオミクス解析システムの確立Principal Investigator

    • Principal Investigator
      眞貝 洋一
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Genome biology
    • Research Institution
      Kyoto University
  •  The Epigenomic Analysis of Obesity and Insulin Resistance

    • Principal Investigator
      SAKAI Juro
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Histone demethylase Jmjd1a as a regulator of glycolipid metabolism

    • Principal Investigator
      INAGAKI Takeshi
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      The University of Tokyo
  •  ヒストンメチル化酵素複合体による転写抑制機構の分子基盤

    • Principal Investigator
      立花 誠
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Regulation and roles of histone methylation dynamics in germ-lineage cellsPrincipal Investigator

    • Principal Investigator
      SHINKAI Yoichi
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
      Kyoto University
  •  Establishment of prion deficient cells in cattlePrincipal Investigator

    • Principal Investigator
      SHINKAI Yoichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      生物資源科学
    • Research Institution
      KYOTO UNIVERSITY
  •  Analysis of molecular regulation on female reproductive tract during fertilization using genetic model mice

    • Principal Investigator
      ARAKI Yoshihiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Yamagata University
  •  Identification of epigenetic protein complexes and functional analyses

    • Principal Investigator
      KATO Hiroyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      National Institute of Infectious Diseases
  •  Molecular Mechanism for cellular senescence and immortalizationPrincipal Investigator

    • Principal Investigator
      SHINKAI Yoichi
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  抗原レセプター対立形質排除の破綻したマウスの作製Principal Investigator

    • Principal Investigator
      真貝 洋一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  哺乳類テロメア維持の新たな分子機構の解析Principal Investigator

    • Principal Investigator
      真貝 洋一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  ESTABLISHMENT OF GERM-LINE COMPETENT EMBRYONIC STEM CELLS LACKING MOUSE OVIDUCT-SPECIFIC GLYCOPROTEIN GENEPrincipal Investigator

    • Principal Investigator
      SHINKAI Yoichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      KYOTO UNIVERSIY

All 2023 2022 2021 2020 2019 2018 2017 2015 2013 2012 2011 2010 2009 2008 2006 2005 2004 2002 2001 Other

All Journal Article Presentation Book

  • [Book] エピジェネティクス2013

    • Author(s)
      眞貝 洋一
    • Total Pages
      282
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Book] エピジェネティクス2013

    • Author(s)
      眞貝洋一
    • Total Pages
      282
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Book] エピジェネティクスキーワード辞典2013

    • Author(s)
      眞貝 洋一
    • Total Pages
      315
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Book] エピジェネティクスキーワード辞典2013

    • Author(s)
      眞貝洋一
    • Total Pages
      315
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Book] Mammalian epigenetics in biology and medicine2013

    • Author(s)
      Ishino F. Shinkai Y. and Whitelaw E
    • Total Pages
      368
    • Publisher
      Philos Trans R Soc Lond B Biol Sci.
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Book] 実験医学別冊 エピジェネティクス実験プロトコール編2008

    • Author(s)
      牛島俊和、眞貝洋一
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression2023

    • Author(s)
      Takase S, Hiroyama T, Shirai F, Maemoto Y, Nakata A, Arata M, Matsuoka S, Sonoda T, Niwa H, Sato S, Umehara T, Shirouzu M, Nishigaya Y, Sumiya T, Hashimoto N, Namie R, Usui M, Ohishi T, Ohba SI, Kawada M, Hayashi Y, Harada H, Yamaguchi T, Shinkai Y, Nakamura Y, Yoshida M, Ito A
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 23-23

    • DOI

      10.1038/s41467-022-35404-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19462, KAKENHI-PROJECT-22KJ2790, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-23K24166, KAKENHI-PROJECT-22K06783, KAKENHI-PROJECT-19H05640, KAKENHI-PROJECT-19H04355, KAKENHI-PLANNED-23H04882
  • [Journal Article] The fluid factor OVGP1 provides a significant oviductal microenvironment for the reproductive process in golden hamster2023

    • Author(s)
      Yamatoya Kenji、Kurosawa Masaru、Hirose Michiko、Miura Yoshiki、Taka Hikari、Nakano Tomoyuki、Hasegawa Akiko、Kagami Kyosuke、Yoshitake Hiroshi、Goto Kaoru、Ueno Takashi、Fujiwara Hiroshi、Shinkai Yoichi、Kan Frederick W K、Ogura Atsuo、Araki Yoshihiko
    • Journal Title

      Biology of Reproduction

      Volume: 110 Issue: 3 Pages: 465-475

    • DOI

      10.1093/biolre/ioad159

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-20K07834, KAKENHI-PROJECT-22K09648, KAKENHI-PROJECT-21K09503, KAKENHI-PROJECT-18KK0256, KAKENHI-PLANNED-19H05758, KAKENHI-PROJECT-23K27096
  • [Journal Article] ヘテロクロマチン形成におけるヒストン修飾の意義2023

    • Author(s)
      福田 渓 , 眞貝 洋一
    • Journal Title

      生体の化学

      Volume: 74 Pages: 223-228

    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Journal Article] Epigenetic plasticity safeguards heterochromatin configuration in mammals2023

    • Author(s)
      Fukuda Kei、Shimi Takeshi、Shimura Chikako、Ono Takao、Suzuki Takehiro、Onoue Kenta、Okayama Satoko、Miura Hisashi、Hiratani Ichiro、Ikeda Kazuho、Okada Yasushi、Dohmae Naoshi、Yonemura Shigenobu、Inoue Azusa、Kimura Hiroshi、Shinkai Yoichi
    • Journal Title

      Nucleic Acids Research

      Volume: - Issue: 12 Pages: 6190-6207

    • DOI

      10.1093/nar/gkad387

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04764, KAKENHI-PLANNED-18H05527, KAKENHI-PLANNED-18H05530, KAKENHI-PLANNED-19H05754, KAKENHI-PROJECT-22H00413, KAKENHI-PROJECT-21H02684
  • [Journal Article] Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors2022

    • Author(s)
      Fang Qi、Kimura Yusuke、Shimazu Tadahiro、Suzuki Takehiro、Yamada Ayumi、Dohmae Naoshi、Iwasaki Shintaro、Shinkai Yoichi
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 4104-4104

    • DOI

      10.1038/s41598-022-08061-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19K22406
  • [Journal Article] METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance2022

    • Author(s)
      Matsuura-Suzuki Eriko、Shimazu Tadahiro、Takahashi Mari、Kotoshiba Kaoru、Suzuki Takehiro、Kashiwagi Kazuhiro、Sohtome Yoshihiro、Akakabe Mai、Sodeoka Mikiko、Dohmae Naoshi、Ito Takuhiro、Shinkai Yoichi、Iwasaki Shintaro
    • Journal Title

      eLife

      Volume: 11 Pages: 1-33

    • DOI

      10.7554/elife.72780

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21H05281, KAKENHI-PLANNED-22H05019, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20K06497, KAKENHI-PROJECT-21K06026, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-23K23481, KAKENHI-ORGANIZER-22H05017
  • [Journal Article] OVGP1 is an oviductal fluid factor essential particularly for early embryonic development in golden hamsters2022

    • Author(s)
      Yamatoya Kenji、Kurosawa Masaru、Hirose Michiko、Miura Yoshiki、Taka Hikari、Nakano Tomoyuki、Hasegawa Akiko、Kagami Kyosuke、Yoshitake Hiroshi、Goto Kaoru、Ueno Takashi、Fujiwara Hiroshi、Shinkai Yoichi、Kan Frederick W. K.、Ogura Atsuo、Araki Yoshihiko
    • Journal Title

      bioRxiv

      Volume: - Pages: 513711-513711

    • DOI

      10.1101/2022.10.25.513711

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09503, KAKENHI-PROJECT-20K09608, KAKENHI-PROJECT-18KK0256
  • [Journal Article] Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells2022

    • Author(s)
      Fukuda Kei、Makino Yoshinori、Kaneko Satoru、Shimura Chikako、Okada Yuki、Ichiyanagi Kenji、Shinkai Yoichi
    • Journal Title

      eLife

      Volume: 11

    • DOI

      10.7554/elife.76822

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991
  • [Journal Article] Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome2021

    • Author(s)
      Yamada Ayumi、Hirasawa Takae、Nishimura Kayako、Shimura Chikako、Kogo Naomi、Fukuda Kei、Kato Madoka、Yokomori Masaki、Hayashi Tetsutaro、Umeda Mana、Yoshimura Mika、Iwakura Yoichiro、Nikaido Itoshi、Itohara Shigeyoshi、Shinkai Yoichi
    • Journal Title

      iScience

      Volume: 24 Issue: 7 Pages: 102741-102741

    • DOI

      10.1016/j.isci.2021.102741

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-21H02394
  • [Journal Article] A cost efficient protocol to introduce epitope tags by CRISPR-Cas9 mediated gene knock-in with asymmetric semi-double stranded template2021

    • Author(s)
      Fang Qi、Shinkai Yoichi
    • Journal Title

      MethodsX

      Volume: 8 Pages: 101365-101365

    • DOI

      10.1016/j.mex.2021.101365

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991
  • [Journal Article] Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases2021

    • Author(s)
      Fukuda Kei、Shimura Chikako、Miura Hisashi、Tanigawa Akie、Suzuki Takehiro、Dohmae Naoshi、Hiratani Ichiro、Shinkai Yoichi
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 571-571

    • DOI

      10.1038/s42003-021-02089-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16049, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-20K20582
  • [Journal Article] A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin β-cluster genes in the developing brain2021

    • Author(s)
      Balan Shabeesh、-25名-, Shinkai Yoichi、Yoshikawa Takeo
    • Journal Title

      Molecular Psychiatry

      Volume: 26 Issue: 12 Pages: 7550-7559

    • DOI

      10.1038/s41380-021-01199-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-19H03581, KAKENHI-PROJECT-18K07578
  • [Journal Article] Propargylic Se-adenosyl-l-selenomethionine: A Chemical Tool for Methylome Analysis2021

    • Author(s)
      Sohtome Yoshihiro、Shimazu Tadahiro、Shinkai Yoichi、Sodeoka Mikiko
    • Journal Title

      Accounts of Chemical Research

      Volume: 54 Issue: 20 Pages: 3818-3827

    • DOI

      10.1021/acs.accounts.1c00395

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19156, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-17H02213
  • [Journal Article] DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency2021

    • Author(s)
      Taguchi Jumpei、Shibata Hirofumi、Kabata Mio、Kato Masaki、Fukuda Kei、Tanaka Akito、Ohta Sho、Ukai Tomoyo、Mitsunaga Kanae、Yamada Yosuke、Nagaoka So I、Yamazawa Sho、Ohnishi Kotaro、Woltjen Knut、Ushiku Tetsuo、Ozawa Manabu、Saitou Mitinori、Shinkai Yoichi、Yamamoto Takuya、Yamada Yasuhiro
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 5041-5041

    • DOI

      10.1038/s41467-021-25249-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K21352, KAKENHI-PROJECT-20H03162, KAKENHI-PLANNED-18H05530, KAKENHI-PUBLICLY-20H05384, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-20K15801
  • [Journal Article] The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex2020

    • Author(s)
      Tsusaka Takeshi、Fukuda Kei、Shimura Chikako、Kato Masaki、Shinkai Yoichi
    • Journal Title

      Epigenetics & Chromatin

      Volume: 13 Issue: 1 Pages: 52-52

    • DOI

      10.1186/s13072-020-00374-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991
  • [Journal Article] SETDB1-Mediated Silencing of Retroelements2020

    • Author(s)
      Fukuda Kei、Shinkai Yoichi
    • Journal Title

      Viruses

      Volume: 12 Issue: 6 Pages: 596-596

    • DOI

      10.3390/v12060596

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991
  • [Journal Article] Microrheology for Hi-C Data Reveals the Spectrum of the Dynamic 3D Genome Organization2020

    • Author(s)
      Soya Shinkai, Takeshi Sugawara, Hisashi Miura, Ichiro Hiratani, Shuichi Onami
    • Journal Title

      Biophysical Journal

      Volume: 118 Issue: 9 Pages: 2220-2228

    • DOI

      10.1016/j.bpj.2020.02.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15050, KAKENHI-PUBLICLY-18H04720, KAKENHI-PLANNED-18H05412, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-20K08698
  • [Journal Article] Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection.2019

    • Author(s)
      Yeung WKA, Brind’Amour J, Hatano Y, Yamagata K, Feil R, Matthew C. Lorincz MC, Tachibana M, Shinkai Y, Sasaki H*.
    • Journal Title

      Cell Rep.

      Volume: 27 Issue: 1 Pages: 282-293

    • DOI

      10.1016/j.celrep.2019.03.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-19K22388, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06424, KAKENHI-PLANNED-18H05528, KAKENHI-PROJECT-18H02357, KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-18H05214
  • [Journal Article] Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation2019

    • Author(s)
      Kori, S. Ferry, L. Matano, S. Jimenji, T. Kodera, N. Tsusaka, T. Matsumura, R. Oda, T. Sato, M. Dohmae, N. Ando, T. Shinkai, Y. Defossez, P. A. Arita, K.
    • Journal Title

      Structure

      Volume: 27 Issue: 3 Pages: 1-12

    • DOI

      10.1016/j.str.2018.11.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19345, KAKENHI-PLANNED-18H05530, KAKENHI-PLANNED-26119003, KAKENHI-PROJECT-18H02391, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-18H03991
  • [Journal Article] ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination2019

    • Author(s)
      Tsusaka T. Shimura C. *Shinkai Y.
    • Journal Title

      EMBO reports

      Volume: 20 Issue: 12

    • DOI

      10.15252/embr.201948297

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991
  • [Journal Article] A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing2018

    • Author(s)
      Kato Masaki、Takemoto Keiko、Shinkai Yoichi
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41467-018-04132-9

    • NAID

      120006466661

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26250039
  • [Journal Article] Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8.2018

    • Author(s)
      Tsusaka T, Kikuchi M, Shimazu T, Suzuki T, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Takashi Umehara T, Shinkai Y*.
    • Journal Title

      Epigenetics and chromatin.

      Volume: 11 Issue: 1 Pages: 56-56

    • DOI

      10.1186/s13072-018-0231-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-17H02213, KAKENHI-PROJECT-18H03991
  • [Journal Article] A CRISPR knockout screen Identifies SETDB1-target retroelement silencing factors in embryonic stem cells2018

    • Author(s)
      Fukuda Kei、Okuda Akihiko、Yusa Kosuke、Shinkai Yoichi
    • Journal Title

      Genome Research

      Volume: 28 Issue: 6 Pages: 1-13

    • DOI

      10.1101/gr.227280.117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250039, KAKENHI-PUBLICLY-16H01220, KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-16H05143, KAKENHI-PROJECT-18H03991
  • [Journal Article] G9a-dependent histone methylation can be induced in G1 phase of cell cycle.2018

    • Author(s)
      Fukuda M, Sakaue-Sawano A, Shimura C, Tachibana M, Miyawaki A, Shinkai Y.
    • Journal Title

      Sci. Rep.

      Volume: 9 Issue: 1 Pages: 956-956

    • DOI

      10.1038/s41598-018-37507-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05948, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-18H05530, KAKENHI-PLANNED-17H06424, KAKENHI-PROJECT-18H03991, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation2017

    • Author(s)
      Ferry L、Fournier A、Tsusaka T、Adelmant G、Shimazu T、Matano S、Kirsh O、Amouroux R、Dohmae N、Suzuki T、Filion GJ、Deng W、de Dieuleveult M、Fritsch L、Kudithipudi S、Jeltsch A、Leonhardt H、Hajkova P、Marto JA、Arita K、Shinkai Y、Defossez P-A
    • Journal Title

      Molecular Cell

      Volume: 67 Issue: 4 Pages: 550-565

    • DOI

      10.1016/j.molcel.2017.07.012

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250039
  • [Journal Article] Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male germ cells.2013

    • Author(s)
      Deguchi, K. Nagamatsu, G. Miyachi, H. Kato, Y. Morita, S. Kimura, H. Kitano, S. Hatada, I. Saga, Y. Tachibana. M. and Shinkai.Y
    • Journal Title

      Biol. Reprod.

      Volume: 88 Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development2012

    • Author(s)
      Tan, S. Nishi, M. Ohtsuka, T. Matsui, T. Takemoto, K. Kamio-Miura, A. Aburatani, H. Shinkai, Y. and Kageyama, R
    • Journal Title

      Development

      Volume: 139 Pages: 3806-3816

    • URL

      http://dev.biologists.org/content/139/20/3806.long

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Journal Article] PGC7 binds histone H3K9me2 to protect against conversion of 5MeC to 5HmC in early embryos2012

    • Author(s)
      Nakamura, T., Liu, Y.U., Nakashima, H., Umehara, H., Inoue, K., Matoba, S., Tachibana, M., Ogura, A., Shinkai, Y., Nakano, T
    • Journal Title

      Nature

      Volume: 486 Issue: 7403 Pages: 415-419

    • DOI

      10.1038/nature11093

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-19061001, KAKENHI-PLANNED-20062005, KAKENHI-PLANNED-20062007, KAKENHI-PUBLICLY-23013016, KAKENHI-PROJECT-23220011, KAKENHI-PROJECT-23680048, KAKENHI-PROJECT-23770224, KAKENHI-PROJECT-24249018, KAKENHI-PROJECT-24659135
  • [Journal Article] Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development.2012

    • Author(s)
      Tan, S. Nishi, M. Ohtsuka, T. Matsui, T. Takemoto, K. Kamio-Miura, A. Aburatani, H. Shinkai, Y. and Kageyama, R
    • Journal Title

      Development

      Volume: 139 Pages: 3806-3816

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] DNA damage signalling triggers degradation of histone methyltransferases through APC/C^<Cdh1> in senescent cells2012

    • Author(s)
      Takahashi, A.Imai, Y.Yamakoshi, K.Kuninaka, S.Ohtani, N.Yoshimoto, S.Hori, S.Tachibana, M.Anderton, E.Takeuchi, T.Shinkai, Y.Peters, G.Saya, H., Hara, E.
    • Journal Title

      Mol Cell

      Volume: 45 Pages: 123-131

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements and chimaeric transcripts in mouse ES cells2011

    • Author(s)
      Karimi, M.M.Goyal, P.Maksakova, I.A.Bilenky, M.Leung, D.Tang, J.X.Shinkai, Y.Mager, D.L.Jones, S.Hirst M., Lorincz, M.C.
    • Journal Title

      Cell Stem Cell

      Volume: 8 Pages: 676-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] H3K9 methyltransferase G9a and the related molecule GLP2011

    • Author(s)
      Shinkai Y, Tachibana M
    • Journal Title

      Gene Dev.

      Volume: 25(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] H3K9 methyltransferase G9a and the related molecule GLP.2011

    • Author(s)
      Shinkai, Y. and Tachibana, M
    • Journal Title

      Genes Dev.

      Volume: 25 Pages: 781-788

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a2011

    • Author(s)
      Chang, Y.Sun, L.Kokura, K.Horton, J.R.Fukuda, M.Espejo, A.Izumi, V.Koomen, J.M.Bedford, M.T.Zhang, X.Shinkai, Y.Fang, J., Cheng, X.
    • Journal Title

      Nature Commun

      Volume: 2 Pages: 533-533

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling2011

    • Author(s)
      Hayashi-Takanaka, Y.Yamagata, K.Wakayama, T.Stasevich, T.J.Kainuma, T.Tsurimoto, T.Tachibana, M.Shinkai, Y.Kurumizaka, H.Nozaki, N., Kimura, H.
    • Journal Title

      Nucleic Acids Res

      Volume: 39 Pages: 6475-6488

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements and chimaeric transcripts in mouse ES cells.2011

    • Author(s)
      Karimi, M.M. Goyal, P. Maksakova, I.A. Bilenky, M. Leung, D. Tang, J.X. Shinkai, Y. Mager, D.L. Jones, S. Hirst M. and Lorincz, M.C
    • Journal Title

      Cell Stem Cell

      Volume: 8 Pages: 676-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] H3K9 methyltransferase G9a and the related molecule GLP.2011

    • Author(s)
      Shinkai Y., Tachibana M.
    • Journal Title

      Genes Dev. 25

      Pages: 781-788

    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] HP1γ links histone methylation marks to meiotic synapsis in mice2011

    • Author(s)
      Takada, Y.Naruse, C.Costa, Y.Shirakawa, T.Tachibana, M.Sharif, J.Kezuka-Shiotani, F.Kakiuchi, D.Masumoto, H.Shinkai, Y.Ohbo, K.Peters, A.H.F.M.Turner, J.M.A.Asano, M., Koseki, H.
    • Journal Title

      Development

      Volume: 138 Pages: 4207-4217

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements andchimaeric transcripts in mouse ES cells.2011

    • Author(s)
      Karimi, M.M.Goyal, P.Maksakova, I.A.Bilenky, M.Leung, D.Tang, J.X.Shinkai, Y.Mager, D.L.Jones, S.Hirst M., Lorincz, M.C.
    • Journal Title

      Cell Stem Cell. in press

    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.2010

    • Author(s)
      Matsui, T.Leung, D.Miyashita, H.Maksakova, I.A.Miyachi, H.Kimura, H.Tachibana, M.Lorincz, M.C., Shinkai, Y.
    • Journal Title

      Nature. 464

      Pages: 927-931

    • NAID

      120002140757

    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.2010

    • Author(s)
      Matsui, T^#. Leung, D^#. Miyashita, H. Maksakova, I.A. Miyachi, H. Kimura, H. Tachibana, M. Lorincz, M.C. and Shinkai, Y
    • Journal Title

      Nature.

      Volume: 464 Pages: 927-931

    • NAID

      120002140757

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Histone H1 null vertebrate cells exhibit altered nucleosome architecture.2010

    • Author(s)
      Hashimoto, H.Takami, Y.Sonoda, E.Iwasaki, T.Iwano, H.Tachibana, M.Takeda, S.Nakayama, T.Kimura, H., Shinkai, Y.
    • Journal Title

      Nucleic Acids Res. 38

      Pages: 3533-3545

    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Obesity and metabolic syndrome in histone demethylase JHDM2a deficient mice.2009

    • Author(s)
      Inagaki, T^#. Tachibana, M^#. Magoori, K. Kudo, H. Tanaka, T. Okamura, M. Naito, M. Kodama, T. Shinkai, Y. and Sakai, Y
    • Journal Title

      Genes to Cells

      Volume: 14 Pages: 991-1001

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Obesity and Metabolic Syndrome in Histone Demethylase JHDM2a Deficient Mice2009

    • Author(s)
      Inagaki T., Tachibana M., Magoori K., Kudo H., Tanaka T., Okamura M., Naito M., Kodama T., Shinkai Y., Sakai J
    • Journal Title

      Genes to Cells

      Volume: 14(8) Issue: 8 Pages: 991-1001

    • DOI

      10.1111/j.1365-2443.2009.01326.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21687013
  • [Journal Article] Identification of new non-histone targets of human G9a protein lysine methyltransferase using peptide arrays2008

    • Author(s)
      Rathert R. Dhayalan A. Murakami H. Zhang X. Tamas R. Jurkowska R. Komatsu Y. Shinkai Y. Cheng X. and Jeltsch A
    • Journal Title

      Nat Chem Biol 4

      Pages: 344-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription2008

    • Author(s)
      Tachibana M. Matsumura Y. Fukuda M. Kimura H. and Shinkai Y
    • Journal Title

      IEMBO J 27

      Pages: 2681-2690

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.2008

    • Author(s)
      Tachibana M.Matsumura Y.Fukuda M.Kimura H., Shinkai Y.
    • Journal Title

      EMBO J. 27

      Pages: 2681-2690

    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] DNA methylation of retrotransposons in stem cells requires the histone-methyltransferase G9a but not its catalytic activity2008

    • Author(s)
      Dong K.D. Maksakova L.A. Mohn F. Leung D. Appanah R. Lee S. Yang H.W. Hager D. Schttheler D. Tachibana M. Shinkai Y. and Lorincz M. C
    • Journal Title

      IEMBO J 27

      Pages: 2691-2701

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.2008

    • Author(s)
      Tachibana M. Matsumura Y. Fukuda M. Kimura H. and Shinkai Y
    • Journal Title

      EMBO J.

      Volume: 27 Pages: 2681-2690

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Journal Article] Rad54 is dispensable for the ALT pathway.2006

    • Author(s)
      Akiyama, K., Yusa, K., Hashimoto, H., Poonepalli, A., Hande, M.P., Kakazu, N., Takeda, J., Tachibana M., Shinkai, Y.
    • Journal Title

      Genes to Cells 11

      Pages: 1305-1315

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Rad54 is dispensable for the ALT pathway.2006

    • Author(s)
      Akiyama, K.Yusa, K.Hashimoto, H.Poonepalli, A.Hande, M.P.Kakazu, N.Takeda, J.Tachibana, M., Shinkai, Y.
    • Journal Title

      Genes to Cells 11

      Pages: 1305-1315

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.2005

    • Author(s)
      Kanatsu-Shinohara, M.Ogonuki, N., Iwano, T., Lee, J., Kazuki, Y., Inoue, K., Miki, H., Takehashi, M., Toyokuni, S., Shinkai, Y., Oshimura, M., Ishino, F., Ogura, A., Shinohara, T.
    • Journal Title

      Development 132

      Pages: 4155-4163

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Genetic and epigenetic properties of mouse male germline stem cells during long-term culture.2005

    • Author(s)
      Kanatsu-Shinohara, M., Ogonuki, N., Iwano, T., Lee, J., Kazuki, Y., Inoue, K., Miki, H., Takehashi, M., Toyokuni, S., Shinkai, Y., Oshimura, M., Shino, F., Ogura, A., Shinohara, T.
    • Journal Title

      Development 132

      Pages: 4155-4163

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Importance of TRF1 for fun ctional telomere structure.2004

    • Author(s)
      Iwano, T.Tachibana, M.Reth, M., Shinkai, Y.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 1442-1448

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Importance of TRF1 for functional telomere structure.2004

    • Author(s)
      Iwano, T., Tachibana, M., Reth, M., Shinkai, Y.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 1442-1448

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Free Full Text G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.2002

    • Author(s)
      Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y
    • Journal Title

      Genes Dev. 16

      Pages: 1779-1791

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Free Full Text G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.2002

    • Author(s)
      Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y.
    • Journal Title

      Genes Dev. 16

      Pages: 1779-1791

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3.2001

    • Author(s)
      Tachibana M, Sugimoto K, Fukushima T, Shinkai Y.
    • Journal Title

      J. Mol. Chem. 276

      Pages: 25309-25317

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Journal Article] Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3.2001

    • Author(s)
      Tachibana M, Sugimoto K, Fukushima T, Shinkai Y
    • Journal Title

      J. Mol. Chem. 276

      Pages: 25309-25317

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13043024
  • [Presentation] クロマチンリモデリング酵素HELLSと複合体を形成するCDCA7タンパク質の機能ドメインの同定2023

    • Author(s)
      新海暁男、眞貝洋一
    • Organizer
      第16回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] エピゲノム可塑性によるヘテロクロマチン維持機構2023

    • Author(s)
      志村知古、福田渓、井上梓、眞貝洋一
    • Organizer
      第16回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2023

    • Author(s)
      白井温子、宮野加菜、大関淳一郎、舛本寛、中山学、阿部訓也、鈴木伸之介、眞貝洋一
    • Organizer
      第16回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] モデルマウスを用いたクリーフストラ症候群症状改善方法の探究2022

    • Author(s)
      山田亜夕美、西村佳也子、眞貝洋一
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] タンパク質ヒスチジンπ型メチル化酵素欠損マウスは胎生致死になる2022

    • Author(s)
      島津忠広、芳本玲、事柴芳、鈴木建裕、赤壁麻衣、五月女宣裕、袖岡幹子、堂前直、眞貝洋一
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] ヘテロクロマチンの核内空間制御におけるクロマチン修飾の役割2022

    • Author(s)
      福田渓、志村知古、志見剛、木村宏、眞貝 洋一
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] H3K9 and H3K27 methylation pathways exclusively and coordinately regulate heterochromatin organization2022

    • Author(s)
      Shinkai Yoichi
    • Organizer
      The 30th Hot Spring Harbor International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] エピゲノム可塑性によるヘテロクロマチン維持機構2022

    • Author(s)
      福田渓、井上梓、志村知古、眞貝洋一
    • Organizer
      第40 回染色体ワークショップ/第21 回核ダイナミクス研究会合同集会
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] エピゲノム可塑性によるヘテロクロマチン維持機構2022

    • Author(s)
      福田渓、井上梓、志村知古、眞貝洋一
    • Organizer
      第40 回染色体ワークショップ/第21 回核ダイナミクス研究会合同集会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 哺乳類でのヘテロクロマチンのエピジェネティック可塑性2022

    • Author(s)
      眞貝洋一
    • Organizer
      日本遺伝学会第94回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] リボソームタンパク質に起きるヒスチジンメチル化修飾の機能-コドンの読み取り速度を調節し、高品質タンパク質を合成する-2022

    • Author(s)
      松浦絵里子、島津忠広、髙橋真梨、事柴芳、鈴木健裕、柏木一宏、五月女宜裕、赤壁麻依、袖岡幹子、堂前直、伊藤拓宏、眞貝洋一、岩崎信太郎
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 哺乳類でのヘテロクロマチンのエピジェネティック可塑性2022

    • Author(s)
      眞貝洋一
    • Organizer
      日本遺伝学会第94回大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] ヒスチジンメチル化修飾の分子標的に関する生化学的解析2022

    • Author(s)
      渡邊優衣、島津忠広、眞貝 洋一
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] ヒト生殖細胞形成過程におけるトランスポゾンの制御と個体差2022

    • Author(s)
      福田渓、眞貝洋一
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] ヘテロクロマチンの核内空間制御におけるクロマチン修飾の役割2022

    • Author(s)
      福田渓、志村知古、志見剛、木村宏、眞貝 洋一
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22H00413
  • [Presentation] Mitochondrial respiratory complex I failure and cellular CoQ10 deficiency in PYURF KO HeLa cells2022

    • Author(s)
      ファンチー、島津忠広、眞貝洋一
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 出芽酵母を用いたH3K9メチル化酵素/HP1発現による遺伝子発現への影響解析2022

    • Author(s)
      清水泰希、沖昌也、眞貝洋一
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Coordinate regulation of heterochromatin organization by H3K9 and H3K27 methylation pathways2022

    • Author(s)
      Shinkai Yoichi
    • Organizer
      2022 International Symposium of the Epigenome Dynamics Control Research Center
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] ヒト生殖細胞形成過程におけるトランスポゾンの制御と個体差2022

    • Author(s)
      福田渓、眞貝洋一
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Coordinate regulation of heterochromatin organization by H3K9 and H3K27 methylation pathways2022

    • Author(s)
      Yoichi Shinkai
    • Organizer
      2022 International Symposium of the Epigenome Dynamics Control Research Center
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] クリーフストラ症候群モデルマウス脳内における炎症状態の解析2022

    • Author(s)
      山田亜夕美、西村佳也子、眞貝洋一
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] H3K9 and H3K27 methylation pathways exclusively and coordinately regulate heterochromatin organization2022

    • Author(s)
      Yoichi Shinkai
    • Organizer
      The 30th Hot Spring Harbor International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2021

    • Author(s)
      白井温子、大関淳一、舛本寛、中山学、眞貝洋一
    • Organizer
      第38回染色体WS・第19回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] METTL18-mediated histidine methylation on ribosome protein modulates tyrosine translation for proteostasis maintenance2021

    • Author(s)
      Matsuura-Suzuki E. Shimazu T. Takahashi M. Dohmae N. Ito T. Shinkai Y. Iwasaki S
    • Organizer
      RNA2021
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2021

    • Author(s)
      白井温子、大関淳一、舛本寛、中山学、眞貝洋一
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 抑制性クロマチン修飾による核内高次クロマチン構造制御2021

    • Author(s)
      福田渓、志見剛、志村知古、木村宏、眞貝洋一
    • Organizer
      第39回 染色体ワークショップ・第19回 核ダイナミクス研究会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] マウス細胞における異所的へテロクロマチン形成系の構築2021

    • Author(s)
      宮野可菜, 白井温子, 眞貝洋一, 大関淳一郎, 舛本寛, 中山学, 阿部訓也, 鈴木伸之介
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] H3K9メチル化を介した遺伝子発現抑制機構の解明2021

    • Author(s)
      清水泰希、沖昌也、眞貝洋一
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 反復配列に引き起こされる哺乳類異所的 高次クロマチン形成系の構築と解析2021

    • Author(s)
      白井温子、眞貝洋一
    • Organizer
      トランスポゾン研究会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Discovery of novel protein histidine pi-methyltransferase2021

    • Author(s)
      Yoichi Shinkai
    • Organizer
      Pacifichem 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] METTL18-mediated histidine methylation on ribosome protein modulates tyrosine translation for proteostasis maintenance2021

    • Author(s)
      Matsuura-Suzuki E. Shimazu T. Takahashi M. Dohmae N. Ito T. Shinkai Y. Iwasaki S
    • Organizer
      第22回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Discovery of novel protein histidine pi-methyltransferase2021

    • Author(s)
      Shinkai Yoichi
    • Organizer
      Pacifichem 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Reversibility of neurological phenotypes in Kleefstra syndrome model mouse by post-natal GLP supply2021

    • Author(s)
      Yamada A. Hirasawa T. Nishimura K. Shimura C. Kogo N. Fukuda K. Kato M. Yokomori M. Hayashi T. Umeda M. Yoshimura M. Iwakura Y. Nikaido I. Itohara S. Shinkai Y
    • Organizer
      日本人類遺伝学会第66回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Reversibility of neurological phenotypes in Kleefstra syndrome model mouse by post-natal GLP supply2021

    • Author(s)
      6.Yamada A. Hirasawa T. Nishimura K. Shimura C. Kogo N. Fukuda K. Kato M. Yokomori M. Hayashi T. Umeda M. Yoshimura M. Iwakura Y. Nikaido I. Itohara S. Shinkai Y.
    • Organizer
      日本人類遺伝学会第66回大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 反復配列に引き起こされる哺乳類異所的 高次クロマチン形成系の構築と解析2021

    • Author(s)
      白井温子、眞貝洋一
    • Organizer
      トランスポゾン研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Compartment-dependent regulation of heterochromatin formation in mouse embryonic stem cells2021

    • Author(s)
      福田渓、三浦尚、谷川明恵、平谷伊智朗、眞貝洋一
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2021

    • Author(s)
      白井温子、大関淳一、舛本寛、中山学、眞貝洋一
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 自発運動によるクリーフストラ症候群脳神経症状の改善効果2021

    • Author(s)
      山田亜夕美、西村佳也子、眞貝洋一
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 自発運動によるクリーフストラ症候群脳神経症状の改善効果2021

    • Author(s)
      山田亜夕美、西村佳也子、眞貝洋一
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] H3K9メチル化を介した遺伝子発現抑制機構の解明2021

    • Author(s)
      清水泰希、沖昌也、眞貝洋一
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] マウス細胞における異所的へテロクロマチン形成系の構築2021

    • Author(s)
      宮野可菜, 白井温子, 眞貝洋一, 大関淳一郎, 舛本寛, 中山学, 阿部訓也, 鈴木伸之介
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Compartment-dependent regulation of heterochromatin formation in mouse embryonic stem cells2021

    • Author(s)
      福田渓、三浦尚、谷川明恵、平谷伊智朗、眞貝洋一
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 抑制性クロマチン修飾による核内高次クロマチン構造制御2021

    • Author(s)
      福田渓、志見剛、志村知古、木村宏、眞貝洋一
    • Organizer
      第39回 染色体ワークショップ・第19回 核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] METTL18-mediated histidine methylation on ribosome protein modulates tyrosine translation for proteostasis maintenance.2021

    • Author(s)
      Matsuura-Suzuki E. Shimazu T. Takahashi M. Dohmae N. Ito T. Shinkai Y. Iwasaki S.
    • Organizer
      RNA2021
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2021

    • Author(s)
      白井温子、大関淳一、舛本寛、中山学、眞貝洋一
    • Organizer
      第38回染色体WS・第19回核ダイナミクス研究会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] METTL18-mediated histidine methylation on ribosome protein modulates tyrosine translation for proteostasis maintenance2021

    • Author(s)
      12.Matsuura-Suzuki E. Shimazu T. Takahashi M. Dohmae N. Ito T. Shinkai Y. Iwasaki S.
    • Organizer
      第22回日本RNA学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] モデルマウスを用いたKleefstra症候群の神経症状発症機構の解明2019

    • Author(s)
      山田亜夕美、西村佳也子、志村知古、平澤孝枝、眞貝洋一
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] エピゲノム操作による生命機能への介入の可能性2019

    • Author(s)
      眞貝洋一
    • Organizer
      第112回日本繁殖生物学会大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] エピゲノムによる転写抑制機構の解明2019

    • Author(s)
      眞貝洋一
    • Organizer
      第37回染色体ワークショップ・第18回核ダイナミクス研究会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成2019

    • Author(s)
      白井温子、大関淳一郎、舛本寛、中山学、眞貝洋一
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] METTL9はタンパク質のヒスチジン残基をπ-メチル化する酵素である2019

    • Author(s)
      島津忠弘、鈴木健裕、赤壁麻衣、五月女宜裕、 袖岡幹子、堂前直、 眞貝 洋一
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] エピゲノム操作による生命機能への介入の可能性2019

    • Author(s)
      眞貝洋一
    • Organizer
      第112回日本繁殖生物学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Toward biochemical study of the regulation of the de novo DNA methylation.2019

    • Author(s)
      新海暁男、眞貝洋一
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Setdb1-Atf7ip 複合体による転写抑制機構2019

    • Author(s)
      眞貝洋一
    • Organizer
      研究会「染色体研究の最前線2019」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] エピゲノムによる転写抑制機構の解明2019

    • Author(s)
      眞貝洋一
    • Organizer
      第37回染色体ワークショップ・第18回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Uncovering the molecular basis of glutamine methylation of mitochondrial translation release factors2019

    • Author(s)
      Fang Q, Shinkai Y
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Setdb1-Atf7ip 複合体による転写抑制機構2019

    • Author(s)
      眞貝洋一
    • Organizer
      研究会「染色体研究の最前線2019」
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成2019

    • Author(s)
      白井温子、大関淳一郎、舛本寛、中山学、眞貝洋一
    • Organizer
      第13回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Kleefstra症候群モデルマウスを用いた神経症状発症機構の解明2019

    • Author(s)
      山田亜夕美、西村佳也子、志村知古、平澤孝枝、眞貝洋一
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Kleefstra症候群の後天的エピゲノム改変による治療可能性の探求と発症機構の解明2018

    • Author(s)
      山田亜夕美、西村佳也子、志村知古、平澤孝枝、眞貝洋一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] G9aは細胞周期のどのタイミングでヒストンH3K9をメチル化できるのか?2018

    • Author(s)
      福田 幹子、阪上-沢野 朝子、宮脇 敦史、志村 知古、立花 誠、眞貝 洋一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] エピゲノムの確立・維持と可変・可塑性のダイナミクス2018

    • Author(s)
      眞貝洋一
    • Organizer
      日本生化学会北陸支部第36回大会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] H3K9メチル化酵素によるレトロウイルス転写抑制の分子機構2018

    • Author(s)
      眞貝洋一
    • Organizer
      第41回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] 内在性レトロウイルスの活性化機構と自然免疫反応2018

    • Author(s)
      竹本 経緯子、加藤 雅紀、眞貝 洋一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] 内在性レトロウイルスの活性化機構と自然免疫反応2018

    • Author(s)
      竹本 経緯子、加藤 雅紀、眞貝 洋一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Kleefstra症候群モデルマウスの自閉症様表現型は後天的エピゲノム改変により回復できるか-そのタイミングと効果-2018

    • Author(s)
      横森 将輝、加藤 まどか、山田 亜夕美、西村 佳也子、眞貝 洋一、平澤 孝枝
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] エピゲノムの確立・維持と可変・可塑性のダイナミクス2018

    • Author(s)
      眞貝洋一
    • Organizer
      日本生化学会北陸支部第36回大会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] H3K9メチル化酵素によるレトロウイルス転写抑制の分子機構2018

    • Author(s)
      眞貝洋一
    • Organizer
      第41回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Kleefstra症候群の後天的エピゲノム改変による治療可能性の探求と発症機構の解明2018

    • Author(s)
      山田亜夕美、西村佳也子、志村知古、平澤孝枝、眞貝洋一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] G9aは細胞周期のどのタイミングでヒストンH3K9をメチル化できるのか?2018

    • Author(s)
      福田 幹子、阪上-沢野 朝子、宮脇 敦史、志村 知古、立花 誠、眞貝 洋一
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-18H05530
  • [Presentation] Kleefstra症候群モデルマウスの自閉症様表現型は後天的エピゲノム改変により回復できるか-そのタイミングと効果-2018

    • Author(s)
      横森 将輝、加藤 まどか、山田 亜夕美、西村 佳也子、眞貝 洋一、平澤 孝枝
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H03991
  • [Presentation] Role and regulation of histone lysine-9 methylation2017

    • Author(s)
      Shinkai Y.
    • Organizer
      Japan-France EPIGENETICS WORKSHOP 2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250039
  • [Presentation] Epigenetic regulation of transposable element2017

    • Author(s)
      Shinkai Y.
    • Organizer
      熊本大学リエゾンラボ研究会/リーディングプログラム:HIGOプログラム最先端研究セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250039
  • [Presentation] Epigenetic regulation of transposable element2015

    • Author(s)
      眞貝洋一、福田渓、遊佐宏介
    • Organizer
      国際高等研究所研究プロジェクト「クロマチン・デコーディング」2015年度第1 回研究会
    • Place of Presentation
      国際高等研究所(京都府木津川市、日本)
    • Year and Date
      2015-12-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26250039
  • [Presentation] Epigenetic regulation of transposable element2015

    • Author(s)
      Yoichi Shinkai, Kei Fukuda and Yusuke Yusa
    • Organizer
      Conference on Transposition and Genome Engineering 2015
    • Place of Presentation
      奈良春日野国際フォーラム 甍~I・RA・KA~ (奈良市、日本)
    • Year and Date
      2015-11-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26250039
  • [Presentation] Pericentric heterochromatin generated by HP1 interaction-defective Suv39h12013

    • Author(s)
      Yoichi Shinkai
    • Organizer
      Gordon Research Conference "epigenetics"
    • Place of Presentation
      Bryant University, Smithfield, RI, USA
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] ヒストンリジンメチル化による生命機能制御2013

    • Author(s)
      眞貝洋一
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京国際フォーラム,東京
    • Year and Date
      2013-05-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] マウスLTR因子のエピジェネティック制御と近傍遺伝子への影響2013

    • Author(s)
      眞貝洋一
    • Organizer
      国立遺伝学研究所研究集会「転移因子と宿主の相互作用による生命機能」
    • Place of Presentation
      国立遺伝学研究所,三島
    • Year and Date
      2013-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] ESET-mediated endogenous retrovirus silencing2012

    • Author(s)
      Yoichi Shinkai
    • Organizer
      第35回日本分子生物学会大会
    • Place of Presentation
      福岡国際会議場(福岡)(招待講演)
    • Year and Date
      2012-12-13
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET-mediated endogenous retrovirus silencing2012

    • Author(s)
      Yoichi Shinkai
    • Organizer
      第35回日本分子生物学会大会
    • Place of Presentation
      福岡国際会議場,(福岡)
    • Year and Date
      2012-12-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] SUV39H-mediated heterochromatin formation without accumulation of HP12012

    • Author(s)
      Daisuke Muramatsu, Yoichi Shinkai
    • Organizer
      CSH meeting Epigenetics & Chromatin
    • Place of Presentation
      Cold Spring Harbor (USA)
    • Year and Date
      2012-09-14
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET-mediated endogenous retrovirus silencing.2012

    • Author(s)
      Shinkai Y
    • Organizer
      CSH-Asia meeting on "Epigenetics, Chromatin, and Transcription"
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2012-04-25
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET-mediated endogenous retrovirus silencing2012

    • Author(s)
      Yoichi Shinkai
    • Organizer
      CSH-Asia meeting on "Epigenetics, Chromatin, and Transcription"
    • Place of Presentation
      Suzhou (China)(招待講演)
    • Year and Date
      2012-04-25
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] Roles of the histone methyltransferase ESET in brain development : transcriptional regulation of neural developmental genes, endogenous retroviruses (ERVs) and ERV-linked genes2012

    • Author(s)
      SiokLay Tan, Keio Takemoto, Ryoichiro Kageyama, Yoichi Shinkai
    • Organizer
      藤原セミナー
    • Place of Presentation
      芝蘭会館(京都)(招待講演)
    • Year and Date
      2012-08-02
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET-mediated endogenous retrovirus silencing2012

    • Author(s)
      Yoichi Shinkai
    • Organizer
      CSH-Asia meeting on "Epigenetics, Chromatin, and Transcription"
    • Place of Presentation
      Suzhou (China)
    • Year and Date
      2012-04-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] ESET-mediated endogenous retrovirus silencing2011

    • Author(s)
      眞貝洋一
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜、横浜(招待講演)
    • Year and Date
      2011-11-16
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] The role of H3K9 methyltranferase in genome integrity2011

    • Author(s)
      眞貝洋一
    • Organizer
      27th RBC-NIRS International Symposium
    • Place of Presentation
      コープ.イン.京都(京都市)(招待講演)
    • Year and Date
      2011-12-09
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンメチル化ダイナミクスの制御と生殖系列での機能2011

    • Author(s)
      眞貝洋一
    • Organizer
      第4回特定領域研究「生殖系列」班会議
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストン脱メチル化酵素Jmjd1aによる代謝調節2011

    • Author(s)
      稲垣毅、立花誠、眞貝洋一、酒井寿郎
    • Organizer
      第84回日本内分泌学会学術総会
    • Place of Presentation
      神戸国際会議場(兵庫県)(シンポジウム)(招待講演)
    • Year and Date
      2011-04-23
    • Data Source
      KAKENHI-PROJECT-21687013
  • [Presentation] ヒストンメチル化酵素ESETによるES細胞の機能・分化制御機構2011

    • Author(s)
      眞貝洋一
    • Organizer
      第10回日本再生医療学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2011-03-02
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストン脱メチル化酵素Jmjd1aによる代謝調節2011

    • Author(s)
      稲垣毅、立花誠、眞貝洋一、酒井寿郎
    • Organizer
      第84回日本内分泌学会学術総会(シンポジウム)
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-23
    • Data Source
      KAKENHI-PROJECT-21687013
  • [Presentation] ESET-mediated endogenous retrovirus silencing2011

    • Author(s)
      眞貝洋一
    • Organizer
      第34回日本分子生物学会年会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンメチル化酵素ESETによる生命機能制御2011

    • Author(s)
      眞貝洋一
    • Organizer
      第11回日本分子生物学会春季シンポジウム
    • Place of Presentation
      石川県立音楽堂(石川県金沢市)(招待講演)
    • Year and Date
      2011-05-26
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンメチル化酵素ESETによる生命機能制御2011

    • Author(s)
      眞貝洋一
    • Organizer
      第34回日本分子生物学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜(横浜市)(招待講演)
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンリジンメチル化酵素ESET による内在性レトロウイルス抑制機構2010

    • Author(s)
      眞貝洋一、松井稔幸
    • Organizer
      日本遺伝学会第82回大会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンリジンメチル化酵素ESETによる内在性レトロウイルス抑制機構2010

    • Author(s)
      眞貝洋一、松井稔幸
    • Organizer
      日本遺伝学会第82回大会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET2010

    • Author(s)
      Shinkai Y
    • Organizer
      Gordon Research Conference "Chromatin Structure and Function"
    • Place of Presentation
      Bryant University, Smithfield, RI, USA
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.2010

    • Author(s)
      Matsui, T., Leung, D., Miyashita, H., Maksakova, I.A., Miyachi, H., Kimura, H., Tachibana, M., Lorincz, M.C., Shinkai, Y.
    • Organizer
      Gordon Research Conference "Chromatn Structure and Function"
    • Place of Presentation
      Bryant University, Smithfield, RI, USA
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストン脱メチル化酵素Jmjd1aによる糖脂質代謝調節2010

    • Author(s)
      稲垣毅、立花誠、眞貝洋一、酒井寿郎
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21687013
  • [Presentation] Histone methyltransferase ESET constrains endogenous retrovirus (ERV) transcription2010

    • Author(s)
      Shinkai Y
    • Organizer
      International Symposium on "Epigenome Network, Development and Reprogramming of Germ Cells'
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンリジンメチル化酵素ESETによる内在性レトロウイルス抑制機構2010

    • Author(s)
      眞貝洋一
    • Organizer
      日本遺伝学会第82回大会
    • Place of Presentation
      札幌市
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET/SETDB1 is essential for LTR-retroelement silencing in mouse embryonic stem cells.2009

    • Author(s)
      Shinkai Y
    • Organizer
      FASEB Summer Research Conferences, "Epigenetics, Chromatin & Transcription"
    • Place of Presentation
      Snowmass Village, Colorado, USA
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ヒストンリジンメチル化コードと生命機能制御2009

    • Author(s)
      眞貝洋一
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET/SETDB1 is essential for LTR-retroelement silencing in mouse embryonic stem cells.2009

    • Author(s)
      Shinkai Y.
    • Organizer
      FASEB Summer Research Conferences, "Epigenetics, Chromatin & Transcription".
    • Place of Presentation
      Snowmass Village, Colorado, USA
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET/SETDB1 is essential for LTR-retroelement silencing in mouse ES Cells2009

    • Author(s)
      Shinkai Y
    • Organizer
      FASEB Summer Research Conferences "Epigenetics, Chromatin and Transcription"
    • Place of Presentation
      Snowmass Village, Colorado, USA
    • Year and Date
      2009-07-13
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] Function and regulation of histone lysine methylation2008

    • Author(s)
      眞貝洋一
    • Organizer
      第31回日本分子生物学会大会、第81回日本生化学会会合同大会シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] Function and regulation of histone lysine methylation2008

    • Author(s)
      眞貝洋一
    • Organizer
      第31回日本分子生物学会大会、第81回日本生化学会大会合同大会シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] Epigenetic Gene Silencing Mechanisms of the G9a/GLP Histone Methyltransferase Complex.2008

    • Author(s)
      Shinkai, Y
    • Organizer
      6th NIBB-EMBL joint Meeting
    • Place of Presentation
      EMBL Heidelberg, Germany
    • Data Source
      KAKENHI-PLANNED-20062005
  • [Presentation] ESET-mediated endogenous retrovirus silencing

    • Author(s)
      眞貝洋一
    • Organizer
      CSH-Asia meeting on "Epigenetics, Chromatin, and Transcription"
    • Place of Presentation
      Suzhou (China)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] ESET-mediated endogenous retrovirus silencing

    • Author(s)
      Yoichi Shinkai
    • Organizer
      第35回日本分子生物学会大会
    • Place of Presentation
      福岡国際会議場,(福岡)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] ヒストンリジンメチル化による生命機能制御

    • Author(s)
      眞貝 洋一
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京国際フォーラム、 東京
    • Data Source
      KAKENHI-PROJECT-23310138
  • [Presentation] マウスLTR因子のエピジェネティック制御と近傍遺伝子への影響

    • Author(s)
      眞貝 洋一
    • Organizer
      国立遺伝学研究所研究集会「転移因子と宿主の相互作用による生命機能」
    • Place of Presentation
      国立遺伝学研究所、三島
    • Data Source
      KAKENHI-PROJECT-23310138
  • 1.  TACHIBANA Makoto (80303915)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 28 results
  • 2.  SAKAI Juro (80323020)
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    # of Collaborated Products: 4 results
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  • 6.  INAGAKI Takeshi (10507825)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  KODAMA Tatsuhiko (90170266)
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  • 12.  SAKURAI Takeshi (60251055)
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  • 14.  浜窪 隆雄 (90198797)
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  • 15.  平谷 伊智朗 (40583753)
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    # of Collaborated Products: 1 results
  • 16.  小倉 淳郎 (20194524)
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    # of Collaborated Products: 1 results
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  • 19.  小山 恭平 (00818479)
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  • 20.  紙谷 寛之 (30436836)
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    # of Collaborated Products: 0 results
  • 21.  SENDAI Yutaka
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    # of Collaborated Products: 0 results
  • 22.  ITO Takuhiro
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    # of Collaborated Products: 1 results
  • 23.  HARADA Yuka
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    # of Collaborated Products: 1 results
  • 24.  KODERA Noriyuki
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    # of Collaborated Products: 1 results
  • 25.  TAKA Hikari
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  • 26.  KAGA Naoko
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  • 27.  SAKAUE Asako
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  • 28.  原田 浩徳
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