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GOTO Yu-ichi  後藤 雄一

… Alternative Names

GOTO Yuichi  後藤 雄一

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Researcher Number 20225668
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6805-6428
External Links
Affiliation (Current) 2025: 国立研究開発法人国立精神・神経医療研究センター, その他部局等, 理事長特任補佐
2025: 国立健康危機管理研究機構, その他部局等(NCGM), 上級研究員
Affiliation (based on the past Project Information) *help 2017: 国立精神・神経医療研究センター, 神経研究所疾病研究第二部, 部長
2015: 独立行政法人国立精神・神経医療研究センター, 疾病研究第二部, 部長
2014: 国立精神・神経医療研究センター, 神経研究所疾病研究第二部, 部長
2006: National Institute of Neuroscience, Department of Mental Retardation and Birth Defect Research, Director, 神経研究所疾病研究第二部, 部長
2004 – 2005: 国立精神・神経センター, 疾病研究第二部, 部長 … More
2004 – 2005: 国立精神神経センター, 神経研究所, 部長
2002 – 2004: 国立精神・神経センター, 神経研究所・疾病研究第2部, 部長(研究職)
2003: 国立精神・神経センター, 神経研究所, 部長
2002: NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY, DEPARTMENT OF MENTAL RETARDATION AND BIRTH DEFECT RESEARCH, DlRECTOR(Researcher), 部長(研究職)
2001: 国立精神・神経センター, 微細構造, 部長
1999 – 2001: 国立精神神経センター, 神経研究所, 部長
2000: 国立精神・神経センター, 微細構造, 部長(研究職)
2000: National Center of Neurology and Psychiatry, Director, 疾病研究第2部, 部長
1999: 国立精神神経センター, 微細構造部, 部長(研究職)
1999: 国立精神神経センター, 神経研究所・疾病二部, 部長
1998: 国立精神神経センター, 神経研究所・微細構造部, 室長
1997 – 1998: 国立精神・神経センター, 神経研究所・微細構造研究部, 室長
1995 – 1997: 国立精神神経センター, 微細構造研究部, 室長
1996: National Center of Neurology and Psychiatry, Ultrastructural Research, Head, 神経センター神経研究所・微細構造研究部, 室長
1996: Division of Ultrastructural Research, National Institute of Neuroscience, Nation, 神経研究所・微細構造研究部, 室長
1995 – 1996: 国立精神, 神経センター・神経研究所・微細構造研究部, 室長
1995: 国立精神神経センター, 神経研究所微細構造研究部, 室長
1994: National Center of Neurology and Psychiatry Ultrastructural Research Section Chief, 神経研究所・微細構造研究部, 室長
1994: 国立精神神経センター, 神経研究所, 室長
1993: 国立精神・神経センター, 神経研究所・微細構造研究部, 研究員
1992 – 1993: 国立精神, 神経センター神経研究所・微細構造研究部, 研究員
1991 – 1993: National Institute of Neurosicence, NCNP, Division of Ultrastructural Research,, 神経センター・神経研究所・微細構造研究部, 研究員
1992: 国立精神神経センター, 神経研究所微細構造研究部, 研究員
1991: 国立精神神経センター, 神経研究所・微細構造研究部, 研究員
1990: 国立精神, 神経センター神経研究所・微細構造研究部, 研究員 Less
Review Section/Research Field
Principal Investigator
Neurology / Pediatrics
Except Principal Investigator
Neurology / Pediatrics / Pediatrics / Applied health science / Otorhinolaryngology / Laboratory animal science / Laboratory medicine
Keywords
Principal Investigator
MELAS / ミトコンドリア病 / Mitochondrial DNA / ミトコンドリアDNA / germanium / cytochrome c oxidase / cybrids / mitochondrial disaease / KearnsYSayre syndrome / single deletion … More / 定量的PCR法 / ヘテロプラスミー / アミノグリコシド誘発性難聴 / チトクロームc酸化酵素欠損症 / 全周シークエンス / モデル動物 / 血管条 / MIDAS / アンチコドン修飾 / 血管機能障害 / POLG / ミトコンドリアDNA欠乏 / ゲルマニウム / チトクロームc酸化酵素 / サイブリッド / Kearns-Sayre症候群 / 単一欠失 / mitochondrial disease / inborn error of metabolism / molecular genetics / complex II / flavoprotein / succinate dehydrogenase / 電子伝達系 / cDNA / 鉄-イオウ蛋白 / フラビンタンパク / 先天代謝異常 / 分子遺伝学 / 複合体II / フラボプロテイン / こはく酸脱水素酵素 / Gene transfer / Transgenic Mouse / Transfer RNA / Mitochondrial encephalomyopathy / Mitochondria / トランスジュニックマウス / 遺伝子導入 / トランスジェニックマウス / 転移RNA / ミトコンドリア脳筋症 / ミトコンドリア … More
Except Principal Investigator
ミトコンドリアDNA / ミトコンドリア病 / MELAS / ミトコンドリア脳筋症 / MeCP2 / myostatin / nNOS / caveolin-3 / トランスジェニックマウス / 老化 / 病態モデルマウス / mtDNA突然変異 / マウスmtDNA / mtDNA / mitochondrial DNA / メラス / 組織特異性 / 遺伝子診断 / ミトコンドリア / タンパク質分解 / プロテアーゼ / Blue Native 電気泳動 / 先天代謝異常 / 遺伝 / Blue Native電気泳動 / アセンブリーファクター / 呼吸鎖複合体 / ミトコンドリア異常症 / phosphorylation / glial cell / neuronal cell / DNA methylation / Rett syndrome / mental retardation / epigenetics / ノック / ノックアウトマウス / シナプス / ニューロン / 小児疾患 / 蛋白質修飾 / 神経膠細胞 / 神経細胞 / DNAメチレーション / レット症候群 / 精神発達障害 / ゲノム不活化 / signal transduction / muscular dystrophy / モデル動物 / 肥大型心筋症 / eNOS / Smad2 / マイオスタチン / カベオリン / シグナル伝達 / 筋ジストロフィー / nonrandom pattern / HUMARA gene / androgen receptor gene / methylation-specific PCR / carrier detection / methylation / inactivation / X-chromosome / メチレーション / HUMARA遺伝子 / BFL症候群 / アンドロゲン受容体遺伝子 / メチル化特異的PCR / 保因者診断 / メチル化 / 不活化 / X染色体 / ENCEPHALOMYOPATHY / HAIR CELL / STRIA VASCULARIS / COCHLEA / DEAFNESS / MITOCHONDRIAL DNA / guinea pig / germanium / cochlea / deafness / 脳節症 / 脳筋症 / 有毛細胞 / 血管系 / 蝸牛 / 難聴 / ミトコンドリア遺伝子 / mitochondrial tRNA / Disease model mice / Mitochondrial transfer / mtDNA Mutation / Mouse mtDNA / 呼吸欠損株 / マイクロインジェクション法 / マウス受精卵 / ミトコンドリアDNAノックアウトマウス / ミトコンドリア遺伝子病 / 突然変異 / 遺伝子導入 / マウス / ミトコンドリアVRNA / ミトコンドリアtRNA / 病態モデル / ミトコンドリア移植 / mtDNA突然異変 / brain dysfunction / gene analysis / CNS form of CPT II / CPT II deficiency / 脳障害 / 脳型CPTII / CPTII欠損症 / chloroquine / myopathies / beta-APP / Alzheimmer's disease / tau / rimmed vacuoles / アポリポ蛋白E / 熱ショック蛋白70 / チューブリン / β-アミロイド / rimmed vacuole / クロロキン / アミロイドβ前駆体蛋白 / アミロイドβ / アルツハイマー病 / タウ蛋白 / 縁取り空胞 / disease-model mice / mitochondrial KO mice / mtDNA inlroduction / mitochondrial diseases / 糖尿病 / シナプトゾーム / mtDNA欠損細胞 / 疾患モデルマウス / ミトコンドリアノックアウトマウス / mtDNA導入 / ミトコンドリア遺伝子疾患 / Tissue specificity / Mitochondrial angiopathy / mitochondrial encephalomyopathies / 血層異常 / 点変異 / Leigh 脳症 / ミトコンドリア アンギオパチー / metabolic myopathy / dystrophin / Becker type / Duchenne type / progressive muscular dystrophy / mitochondrial DNA mutation / mitochondrial disease / 筋生検 / 組織バンク / 糖原病 / 進行性筋ジストロフィ- / 神経・筋疾患 / 代謝性筋疾患 / ジストロフィン / ベッカー型 / デュシャンヌ型 / 進行性筋ジストロフィー / ミトコンドリアDNA変異 / Myoclonus Epilepsy / Chronic Progressive External Ophthalmoplegia / Mitochondrial DNA / Tissue Specificity / Cytochrome c Oxidase / Mitochondrial Myopathy / MERRF / 慢性外眼筋麻痺 / 慢性外眼麻痺症候群 / チトクロム酸化酵素 / ミトコンドリアミオパチ- / ミオクロヌスてんかん / 慢性外眼筋麻痺症候群 / ミトコンドリアDNA(mtDNA) / チトクロ-ムC酸化酵素 / ミトコンドリアミオパタ- / β酸化 Less
  • Research Projects

    (17 results)
  • Research Products

    (55 results)
  • Co-Researchers

    (36 People)
  •  Functional analysis of the proteases in mitochondrial matrix.

    • Principal Investigator
      Matsushima Yuichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied health science
    • Research Institution
      Kyushu University
  •  The utility of targeted exome sequencing for mitochondrial disorders

    • Principal Investigator
      MATSUSHIMA Yuichi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyushu University
  •  Analysis of respiratory chain complex assembly in mitochondrial disorders

    • Principal Investigator
      Mimaki Masakazu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Teikyo University
      The University of Tokyo
  •  Molecular pathological and biochemical study on pathogenesis caused by mitochondrial DNA abnormalitiesPrincipal Investigator

    • Principal Investigator
      GOTO Yu-ichi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      National Institute of Neuroscience, National Center of Neurology and Psychiatry
  •  Investigation of A Child Disease with Epigenetic Disorder -Rett Syndrome-

    • Principal Investigator
      KUBOTA Takeo
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      University of Yamanashi
  •  Basic research developing a therapy for muscular dystrophy by modulating intracellular signal transduction

    • Principal Investigator
      SUNADA Yoshihide
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kawasaki Medical School
  •  STUDY ON THE MECHANISM OF DEAFNESS ASSOCIATED WITH MITOCHONDRIAL DNA ABNORMALITY

    • Principal Investigator
      YAMASOBA Tatsuya
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Establishment of carrier detection method of X-linked diseases by methylation-specific PCR

    • Principal Investigator
      KUBOTA Takeo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      National Center of Neurology and Psychiatry
      Shinshu University
  •  Generation and application of mtDNA knockout mice as models for mitochondrial diseases

    • Principal Investigator
      HAYASHI Jun-ichi
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      University of Tsukuba
  •  Molecular genetic study of succinate dehydrogenase deficiencyPrincipal Investigator

    • Principal Investigator
      GOTO Yu-ichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience National Center of Neurology and Psychiatry (NCNP)
  •  An experimental study to explore the pathogenetic mechanism of senile plaque formation and neurofibrillar degeneration in Alzheimer's disease

    • Principal Investigator
      NONAKA Ikuya
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Brain type CPT II Deficiency ; CPT II analysis in the brain and its gene mutations.

    • Principal Investigator
      OHTANI Yoshinobu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kumamoto Univ.
  •  Isolation of mtDNA knock-out mice by introduction of disease-related mtDNA mutation

    • Principal Investigator
      HAYASHI Jun-ichi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      University of Tsukuba
  •  Study on gene abnormality of mitochondrial encephalomyopathy and development of its transgenic mousePrincipal Investigator

    • Principal Investigator
      GOTO Yuichi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Center of Neurology and Psychiatry
  •  A study on tissue expression from mitochondrial DNA mutations

    • Principal Investigator
      NONAKA Ikuya
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP)
  •  Establishment of diagnostic networks and DNA bank for neuromuscular disorders

    • Principal Investigator
      NONAKA Ikuya
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP)
  •  Mitochondrial DNA mutations and tissue specificity in mitochondrial myopathies

    • Principal Investigator
      NONAKA Ikuya
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Institute of Neuroscience, NCNP

All 2017 2016 2015 2013 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] 誰でもわかる神経筋疾患119番2007

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      263
    • Publisher
      日本プランニングセンター
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 小児慢性疾患診療マニュアル2006

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      564
    • Publisher
      診断と治療社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 神経疾患最新の治療2006-2008(ミトコンドリア脳筋症)2006

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      345
    • Publisher
      南光堂
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 小児治療指針、小児科診療第9巻増刊号2006

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      923
    • Publisher
      診断と治療社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] EBM神経疾患の治療2007-20082006

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      534
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 遺伝子診断学-遺伝子診断の進歩と遺伝子治療の展望-2005

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      731
    • Publisher
      日本臨床社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 今日の治療指針2005

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      1676
    • Publisher
      医学書院
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 今日の治療と看護2004

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      1586
    • Publisher
      南江堂
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 家庭医学百科2004

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      3229
    • Publisher
      法研
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Book] 痴呆症学32004

    • Author(s)
      後藤雄一(分担執筆)
    • Total Pages
      391
    • Publisher
      日本臨床
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] IBA57 mutations abrogate iron-sulfur cluster assembly leading to cavitating leukoencephalopathy2017

    • Author(s)
      Ishiyama Akihiko、Sakai Chika、Matsushima Yuichi、Noguchi Satoru、Mitsuhashi Satomi、Endo Yukari、Hayashi Yukiko K.、Saito Yoshiaki、Nakagawa Eiji、Komaki Hirofumi、Sugai Kenji、Sasaki Masayuki、Sato Noriko、Nonaka Ikuya、Goto Yu-ichi、Nishino Ichizo
    • Journal Title

      Neurology Genetics

      Volume: 3 Issue: 5

    • DOI

      10.1212/nxg.0000000000000184

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03096, KAKENHI-PROJECT-17H06112
  • [Journal Article] Serum depletion induced cancer stem cell-like phenotype due to nitric oxide synthesis in oncogenic HRas transformed cells.2016

    • Author(s)
      Monji, K., Uchiumi, T., Hoshizawa, S., Yagi, M., Matsumoto, T, Y., Setoyama, D., Matsushima, Y., Gotoh, K., Amamoto, R., and Kang, D.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 46 Pages: 75221-75234

    • DOI

      10.18632/oncotarget.12117

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03096, KAKENHI-PROJECT-15H04764
  • [Journal Article] ECHS1 mutations cause combined respiratory chain deficiency resulting in Leigh syndrome2015

    • Author(s)
      Sakai C, Yamaguchi S, Sasaki M, Miyamoto Y, Matsushima Y, Goto YI
    • Journal Title

      Human Mutation

      Volume: 36 Issue: 2 Pages: 232-239

    • DOI

      10.1002/humu.22730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659498, KAKENHI-PROJECT-25670275, KAKENHI-PROJECT-25253041
  • [Journal Article] Fatal cerebral hemorrage in mitochondrial encephalomyopathy -clinical and pathological data of a case.2006

    • Author(s)
      Kato H, Uchigata M, Iijima M, Shimizu S, Nonaka I, Goto Y
    • Journal Title

      Journal of Neurology 253巻

      Pages: 529-530

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Leber' s hereditary optic neuropathy with dystonia in a Japanese family.2006

    • Author(s)
      Watanabe M, Mita S, Takita T, Goto Y, Uchino M, Imamura S
    • Journal Title

      J Neurol Sci 243

      Pages: 31-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Cochler damage due to germanium-induced mitochondrial dysfunct ion inguinea pigs.2006

    • Author(s)
      Yamasoba T, Goto Y, Komaki H, Mimaki M, Sudo A, Suzuki M
    • Journal Title

      Neuroscience Letters 395巻

      Pages: 18-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Mitochondrial disorder, diabetes mellitus, and findings in three muscles, including the heart.2006

    • Author(s)
      Bhattacharjee M, Venugopal B, Wong KT, Goto Y, Bhattacharjee MB
    • Journal Title

      Ultrasturctural Pathol 30

      Pages: 135-141

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Cochlear damage due to germanium-induced mitochondrial dysfunction in guinea pigs.2006

    • Author(s)
      Yamasoba T, Goto Y, Komaki H, Mimaki M, Sudo A, Suzuki M
    • Journal Title

      Neurosci Lett 395

      Pages: 18-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリアミオパチー2006

    • Author(s)
      後藤雄一
    • Journal Title

      小児科診療 69巻4号

      Pages: 558-563

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリア病による知的発達障害の分子遺伝学2006

    • Author(s)
      後藤雄一
    • Journal Title

      神経進歩 50巻

      Pages: 781-791

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Leber's hereditary optic neuropathy with dystonia ina Japanese family.2006

    • Author(s)
      Watanabe M, Mita S, Takita T, Goto Y, Uchino M, Imamura S
    • Journal Title

      Journal of the Neurological Sciences 243巻

      Pages: 31-34

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Humanin expression in skeletal muscles of patients with chronic progressive external ophthalmoplegia2006

    • Author(s)
      Kin T, Sugie K, Hirano M, Goto Y, Nishino I, Ueno S
    • Journal Title

      Journal of Human Genetics 51巻6号

      Pages: 555-558

    • NAID

      10017608424

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Fatal cerebral hemorrage in mitochondrial encephalomyopathy-clinical and pathological data of a case.2006

    • Author(s)
      Kato H, Uchigata M, Iijima M, Shimizu S, Nonaka I, Goto Y
    • Journal Title

      J Neurol 253

      Pages: 529-530

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Mitochondrial disorder, diabetes mellitus, and findings in three muscles, including the heart.2006

    • Author(s)
      Bhattacharjee M, Venugopal B, Wong KT, Goto Y, Bhattacharjee MB
    • Journal Title

      Ultrastructural Pathology 30巻

      Pages: 135-141

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Humanin expression in skeletal muscles of patients with chronic progressive external ophthalmoplegia.2006

    • Author(s)
      Kin T, Sugie K, Hirano M, Goto Y, Nishino I, Ueno S
    • Journal Title

      J Hum Genet 51

      Pages: 555-558

    • NAID

      10017608424

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Leber's hereditary optic neuropathy with dystonia in a Japanese family.2006

    • Author(s)
      Watanabe M, Mita S, Takita T, Goto Y, Uchino M, Imamura
    • Journal Title

      Journal of the Neurological Sciences 243巻

      Pages: 31-34

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Cochler damage due to germanium-induced mitochondrial dysfunction inguinea pigs.2006

    • Author(s)
      Yamasoba T, Goto Y, Komaki H, Mimaki M, Sudo A, Suzuki M
    • Journal Title

      Neuroscience Letters 395巻

      Pages: 18-22

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes)2006

    • Author(s)
      後藤雄一
    • Journal Title

      Clinical Neuroscience 24巻11号

      Pages: 658-661

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリア病の診断プロセス2006

    • Author(s)
      後藤雄一
    • Journal Title

      Clinical Neuroscience 24巻11号

      Pages: 653-655

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリア病の組織診断-ゴモリ染色、活性染色、免疫染色2005

    • Author(s)
      後藤雄一
    • Journal Title

      臨床検査 49巻1号

      Pages: 45-49

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction.2005

    • Author(s)
      Nakashima-Kamimura N, Asoh S, Ishibashi Y, Mukai Y, Shidara Y, Oda H, Munakata K, Goto Y, Ohta S
    • Journal Title

      J Cell Sci 118(22)

      Pages: 5357-5367

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Vascular involvement in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.2005

    • Author(s)
      Takahashi N, Shimada T, Murakami Y, Katoh H, Oyake N, Ishibashi Y, Nishino I, Nonaka I, Goto Y
    • Journal Title

      Am J Med Sci 329(9)

      Pages: 265-266

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease2005

    • Author(s)
      Kirino Y, Goto Y, Campos Y, Arenas J, Suzuki T
    • Journal Title

      Proceedings of National Academy of Sciences 102巻20号

      Pages: 7127-7132

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Vascular involvement on a patient with mitochondrial mypathy, encephalopathy, lactic acidosis, and stroke-like episodes.2005

    • Author(s)
      Takahashi N, Shimada T, Murakami Y, Katoh H, Oyake N, Ishibashi Y, Nishino I, Nonaka I, Goto Y
    • Journal Title

      The American Journal of Medical Sciences 329巻5号

      Pages: 265-266

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] MIDAS/GPP34, a nuclear gene product, regulates total mitochondri al mass in response to mitochondrial dysfunction.2005

    • Author(s)
      Nakashima-Kamimura N, Asoh T, Ishibashi Y, Mukai Y, shidara Y, Oda H, Munakata K, Goto Y, Ohta S
    • Journal Title

      Journal of Cell Science 118巻22号

      Pages: 5357-5367

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease.2005

    • Author(s)
      Kirino Y, Goto Y, Campos Y, Arenas J, Suzuki T
    • Journal Title

      Proc Natl Acad Sci USA 102

      Pages: 7127-7132

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Audiological features and mitochondrial DNA sequence in a large family carrying mitochondrial A1555G mutation without use of aminoglycoside2005

    • Author(s)
      Matsunaga T, Kumanomido H, Shiroma M, Goto Y, Usami S
    • Journal Title

      Annals of Otology, Rhinology & Laryngology 114巻2号

      Pages: 153-160

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリア脳筋症と小脳障害2005

    • Author(s)
      後藤雄一
    • Journal Title

      Clinical Neuroscience 23巻12号

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction.2005

    • Author(s)
      Nakashima-Kamimura N, Asoh T, Ishibashi Y, Mukai Y, Shidara Y, Oda H, Munakata K, Goto Y, Ohta S
    • Journal Title

      Journal of Cell Science 118巻22号

      Pages: 5357-5367

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Audiological features and mitochondrial DNA sequence in a large family carrying mitochondrial A1555G mutation without use of aminoglycoside2005

    • Author(s)
      Matsunaga T, Kumanomido H, Shiroma M, Goto Y, Usami S
    • Journal Title

      Annals of Otology, Rhinology & Laryngology 114巻2号

      Pages: 153-160

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Methylation status of the p15 and p16 genes in paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia.2005

    • Author(s)
      Hasegawa D, Manabe A, Kubota T, Kawasaki H, Hirose I, Ohtsuka Y, Tsuruta T, Ebihara Y, Goto Y, Zhao XY, Sakashita K, Koike K, Isomura M, Kojima S, Hoshika A, Tsuji K, Nakahata T.
    • Journal Title

      Br J Haematol 128

      Pages: 805-812

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390330
  • [Journal Article] Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease2005

    • Author(s)
      Kirino Y, Goto Y, Campos Y, Arenas J, Suzuki T
    • Journal Title

      Proceedings of National Academy of Sciences 102巻

      Pages: 7127-7132

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] Audiological features and mitochondrial DNA sequence in a large family carrying mitochondrial A1555G mutation without use of aminoglycoside.2005

    • Author(s)
      Matsunaga T, Kumanomido H, Shiroma M, Goto Y, Usami S
    • Journal Title

      Ann Otol Rhinol Laryngol 114

      Pages: 153-160

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリア機能異常と変性性痴呆との関連2004

    • Author(s)
      後藤雄一
    • Journal Title

      日本臨床 62巻増刊号4

      Pages: 220-223

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ミトコンドリア脳筋症の病態と治療への展望2004

    • Author(s)
      後藤雄一
    • Journal Title

      神経治療学 21巻5号

      Pages: 521-528

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390309
  • [Journal Article] ICF syndrome in a girl with DNA hypomethylation but without detectable DNMT3B mutation.2004

    • Author(s)
      Kubota T, Furuumi H, Kamoda T, Iwasaki N, Tobita N, Fujiwara N, Goto Y, Matsui A, Sasaki H, Kajii T.
    • Journal Title

      Am J Med Genet 129A

      Pages: 290-293

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390330
  • [Journal Article] Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease

    • Author(s)
      Kirino Y, Goto Y, Campos Y, Arenas J, Suzuki T
    • Journal Title

      Proceedings of National Academy of Science (印刷中)

    • Data Source
      KAKENHI-PROJECT-16390309
  • [Presentation] Blue-Native PAGE (BN-PAGE) にて呼吸鎖複合体IおよびIV低下を認め、POLG遺伝子異常が判明したミトコンドリア病の一例2015

    • Author(s)
      水野葉子、三牧正和、太田さやか、下田木の実、高橋長久、岩崎博之、岡明、片山菜穂子、生井良幸、水口雅、後藤雄一
    • Organizer
      第57回日本小児神経学会学術集会
    • Place of Presentation
      帝国ホテル大阪(大阪府大阪市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-25461539
  • [Presentation] Leigh 脳症64例における原因遺伝子の検討2013

    • Author(s)
      竹下絵里、三牧正和、吉田寿美子、西野一三、後藤雄一
    • Organizer
      日本人類遺伝学会第58回大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25461539
  • [Presentation] A novel mitochondrial point mutation (m.9155A>G) in two patients with chronic renal failure caused by focal glomerular sclerosis.2013

    • Author(s)
      Eri Takeshita, Masakazu Mimaki, Tomohiro Ishii, Midori Awazu, Masanobu Shinjoh, Yasunobu Hasegawa, Jun Miki, Yoshihiko Hidaka, Etsuko Kumagai, Yu-ichi Goto
    • Organizer
      The 27th Congress of the International Pediatric Association
    • Place of Presentation
      Melbourne
    • Data Source
      KAKENHI-PROJECT-25461539
  • [Presentation] ミトコンドリアDNA m.3243A>G変異を有する308例の検討2013

    • Author(s)
      三牧正和、竹下絵里、西野一三、埜中征哉、後藤雄一
    • Organizer
      第55回日本小児神経学会学術集会
    • Place of Presentation
      大分
    • Data Source
      KAKENHI-PROJECT-25461539
  • [Presentation] ECHS1 の変異は呼吸鎖の活性低下を伴うLeigh症候群を引き起こす

    • Author(s)
      坂井千香、松島雄一、山口清次、佐々木征行、宮本雄策、後藤雄一
    • Organizer
      第14回日本ミトコンドリア学会年会
    • Place of Presentation
      九州大学医学部百年講堂(福岡市)
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25670275
  • [Presentation] Leigh-like syndrome associated with calcification of the bilateral basal ganglia caused by compound heterozygous mutations in mitochondrial poly(A) polymeras

    • Author(s)
      Matsushima Y, Hatakeyama H, Takeshita E, Kitamura T, Kobayashi K, Yoshinaga H, Goto Y
    • Organizer
      EUROMIT 2014, 9th international Meeting on Mitochondrial Pathology
    • Place of Presentation
      タンペレ(フィンランド)
    • Year and Date
      2014-06-15 – 2014-06-19
    • Data Source
      KAKENHI-PROJECT-25670275
  • [Presentation] ミトコンドリア呼吸鎖異常症の診断におけるBlue-Native電気泳動 (BN-PAGE).

    • Author(s)
      水野葉子, 三牧正和, 太田さやか, 下田木の実, 高橋長久, 岩崎博之, 斉藤真木子, 岡明, 水口雅, 後藤雄一
    • Organizer
      第56回日本小児神経学会学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2014-05-29 – 2014-05-31
    • Data Source
      KAKENHI-PROJECT-25461539
  • [Presentation] ショウジョウバエ培養細胞におけるミトコンドリアマトリクスプロテアーゼの機能解析

    • Author(s)
      松島雄一、坂井千香、康東天、後藤 雄一
    • Organizer
      第14回日本ミトコンドリア学会年会
    • Place of Presentation
      九州大学医学部百年講堂(福岡市)
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25670275
  • 1.  NONAKA Ikuya (80040210)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  MATSUSHIMA Yuichi (20571342)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  HAYASHI Jun-ichi (60142113)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KUBOTA Takeo (70293511)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  MATSUOKA Taro
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KIKUCHI Aiko (70159010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HORAI Satoshi (40126157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SUGIE Hideo (60119980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KOBAYASHI Masanori (50170353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ARAHATA Kiichi (30053325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  OHTANI Yoshinobu (10168982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YAMASOBA Tatsuya (60251302)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ASANO Tomoichiro (70242063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ITOH Ken (50251286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  AGEMATSU Kazunaga (60262721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  FUKUSHIMA Yoshimitsu (70273084)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SUNADA Yoshihide (00240713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MURAKAMI Tatsuhumi (30330591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HAGIWARA Hiroki (80276732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NUKINA Nobuyuki (10134595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NAGAI Kaoru (20340953)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  ENDOH Kazushi (70176791)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KOHSAKA Shin-ichi (50112686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ITOH Masayuki (50243407)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  Mimaki Masakazu (40392419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 26.  高井 大策 (20302367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  鈴木 光也 (50302724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  市川 弥生子 (90341081)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  大沢 裕 (80246511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  王 培玉 (10283201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  内海 健 (80253798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 32.  瀬戸山 大樹 (30550850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 33.  SAKUTA Ryoichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  KOBAYASHI Osamu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  西野 一三
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  山口 清次
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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