Sasai Keisuke 笹井啓資

… Alternative Names

SASAI Keisuke 笹井啓資

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Researcher Number	20225858
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 順天堂大学, 医学部, 客員教授 2009 – 2021: Juntendo University, 医学部, 教授 2011: 順天堂大学, 大学院・医学研究科, 教授 2005 – 2008: 新潟大学, 医歯学系, 教授 2002 – 2004: 新潟大学, 大学院・医歯学総合研究科, 教授 … More 2000 – 2001: 順天堂大学, 医学部, 教授 2000: Graduate School of Medicine, KYOTO UNIVERSITY Associate Professor, 医学研究科, 助教授 1999: 京都大学, 大学院・医学研究科, 助教授 1998: Kyoto University, Graduate School of Medicine, Associate Professor, Department of Therapeutic Radiology and Oncology, 医学研究科, 助教授 1995 – 1997: 京都大学, 医学研究科, 講師 1994: 京都大学医学部, 講師 1993: 京都大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Radiation science / Radiation science / Biological Sciences / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / Medical Physics and Radiological Technology / Digestive surgery / Carcinogenesis
Keywords	Principal Investigator 放射線感受性 / 放射線増感 / c-erbB-2 / 放射線治療 / SN-38 / CPT-11 / P53 / 低酸素細胞 / 術中照射 / 低酸素環境 … More / アポトーシス / p53 / トポイソメラーゼI阻害剤 / グルタチオン / EGFR / 食道癌 / Comet Assay / Cu-ATSM / 低酸素細胞分画 / 17-DMAG / Hsp90 / DMAG / 前立腺特異抗原 / 前立腺 / 放射線 / 放射線感受性予測 / コメットアッセイ / 微小核形成試験 / Camptothecin / 蛍光in situ hybridization / 未成熟染色体凝集 / マウスモデル / 放射線増感剤 / 小腸陰窩 / ラジカル / 細胞増殖試験 / in vivo-in vitro assay / 活性酸素 / cleaved caspase-3 / 放射線防護 / edravone / 薬剤開発 / スクリーニングシステム / 放射線防護剤 / エダラボン / HSP90阻害剤 / HIF1α / 放射線増感作用 / 癌幹細胞 / sulfasalazine / 低酸素放細胞射線増感 / Sulfasalazine / ヒートショックプロテイン / がん幹細胞 / Micronucleus assay / Head and neck cancer / Esophageal cancer / Radiosensitivity / Radiation therapy / c-erbB2 / トラスツズマブ / EGFRファミリー / AG1478 / 頭頸部癌 / DNA array / anti-c-erbB-2 antibody / immunohistochemical stain / radiation therapy / esophageal cancer / 抗c-erbB-2抗体 / マイクロアレイ / 抗c-erbB-2 / 免疫組織染色 / PO_2 / IORT / osteosarcoma / pancreatic cancer / tumor hypoxia / hypoxic cell fraction / comet-assay / 子宮頚癌 / 腔内照射 / 子宮頸癌 / コメットアッセイ / 酸素分圧 / 骨肉腫 / 膵癌 / Radiosensitizing effect / Apoptosis / Cell cycle / Radiation / Tirapazamine / 細胞周期 / カンプトテシン / acute hypoxia / chronic hypoxia / Hypoxic cell fraction / PET / ポジトロン / ミトコンドリア / 電子伝達系 / ビスチオセミカルバゾン銅錯体 / DNA障害 / Comet Assay法 / 慢性低酸素細胞 / 急性低酸素細胞 / heat-shock protein 90 / 低酸素 / Hsp90阻害剤 / Hｓｐ90阻害剤 / 低酸素細胞放射線増感 / 蛍光免疫染色 / DNA ploidy / アポプトーシス / 細胞生存率 / DNAプロイディ / DNA二重鎖切断 / リン酸化H2AX / HVJ Envelope / 染色体障害 / HVJ envelope / HVJ-envelope / 前立腺癌 / ワルトマニン / PI3キナーゼ / 放射線増減 / アンチセンス / p85 / PI3 キナーゼ / エリスロボエチソ遺伝子 / Fgr-1 / 低酸素刺激 / 遺伝子治療 / エリスロポイエチン遺伝子 / VEGF遺伝子 / 低酸素応答配列 / コメットアッセイ法 / 未成熟染色体凝集法 / 微小核形成試験法 / 放射線感受性予測法 … More Except Principal Investigator アポトーシス / 微小核形成試験 / Apoptosis / 膵癌 / p16 / 放射線応答遺伝子 / SAGE法 / 低酸素 / 蛍光in situ hybridization / 未成熟染色体凝集法 / 潜在的倍加時間 / Predictive assay / 放射線治療 / 散乱線 / シミュレーション計算 / 画質評価 / モンテカルロシミュレーション / X線グリッド / 画像誘導放射線治療 / コーンビームCT / Daranidazole / Intraoperative radiotherapy / Pancreatic Cancer / Hypoxic cell sensitizer / Radiosensitizer / ドラニダゾール / 術中照射 / 低酸素細胞増感剤 / 放射線増感剤 / Micronucleus assay / 感受性試験 / Pancreatic cancer / integrin αV β3 / Signal transduction / Bcl-X gene / 受容体 / 遺伝子 / 膵癌治療 / DcR3 / インテグリンαvβ3 / シグナル伝達 / Bcl-X遺伝子 / tumor microenvironment / rediation-inducible genes / hypoxia / Gene therapy / 低酸素応答配列 / 低酸素刺激誘導遺伝子 / 放射線誘導遺伝子 / 腫瘍特異的微小環境 / 遺伝子治療 / 間質細胞 / 骨髄微小環境 / miRNA / プロテオミクス / microRNA / 前がん細胞 / 微小環境 / 低線量放射線 / IIs型制限酵素 / 放射線感受性 / 低pH / ATP / 低栄養 / pH / 腫瘍内微小環境 / p53 / 感受性予測法 / FISH / predictive assay / 未成熟染色体凝集 / Gadd45 / P53 / 微小核形成試験法 / predictive assay法 / 放射線感受性予測法 / 分裂細胞分画 Less

Development of a Screening System Using Mouse-model for Chemical Modifiers of Radiation ResponsePrincipal Investigator
- Principal Investigator
  
  Sasai Keisuke
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Juntendo University
Radiosensitization of cancer stem-like cells that thrive under hypoxic conditionsPrincipal Investigator
- Principal Investigator
  
  Sasai Keisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University
Development of antiscatter grid for cone-beam computed tomography in radiation therapy
- Principal Investigator
  
  USUI Keisuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical Physics and Radiological Technology
- Research Institution
  Juntendo University
Hypoxic radiosensitization by DMAG, an Hsp90 inhibitorPrincipal Investigator
- Principal Investigator
  
  Sasai Keisuke
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University
Integrative genomic and proteomic analyses of low-dose ionizing radiation in EBV infected-B cells
- Principal Investigator
  
  TABE Yoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Carcinogenesis
- Research Institution
  Juntendo University
Prediction of radiosensitivity using phosphorylation of histone H2AX in human tumor cell linesPrincipal Investigator
- Principal Investigator
  
  SASAI Keisuke
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University
Development of a method of prediction for tumor cell radiosensitivity using Premature Chromosome CondensationPrincipal Investigator
- Principal Investigator
  
  SASAI Keisuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Niigata University
Development of a Predictive Assay for Radiosensitivity of Esophageal and Head and Neck Cancers and Modification of the Sensitivity Using Anti-c-erbB 2 CompoundsPrincipal Investigator
- Principal Investigator
  
  SASAI Keisuke
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Niigata University
Development of a predictive assay for radiosensitivity of esophageal cancerPrincipal Investigator
- Principal Investigator
  
  SASAI Keisuke
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  NIIGATA UNIVERSITY
放射線治療後の正常前立腺経時変化に関する研究(前立腺特異抗原および組織を中心に)Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
放射線治療後の正常前立腺由来前立腺特異抗原の経時変化に関する研究Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
アンチセンスを用いた腫瘍の放射線感受性増強に関する基礎的研究Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University
  Kyoto University
SAGEを用いた新規の放射線応答遺伝子の探索
- Principal Investigator
  
  平岡真寛
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Basic studies on combination of new hypoxic cell sensitizers and intraoperative radiotherapy for unresectable pancreatic cancer
- Principal Investigator
  
  SHIBAMOTO Yuta
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
Measurement of the hypoxic cell fraction in human tumors using a comet assayPrincipal Investigator
- Principal Investigator
  
  SASAKI Keisuke
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  JUNTENDO UNIVERSITY
  Kyoto University
Nove| strategies for cancer treatment with tumor-specific gene therapy and radiotherapy
- Principal Investigator
  
  HIRAOKA Masahiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
Molecular cancer therapy based on the pathological analysis of the pancreatic cancer
- Principal Investigator
  
  HOSOTANI Ryo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Digestive surgery
- Research Institution
  KYOTO UNIVERSITY
Development of predictive assays for radiosensitivity, chemosensitivit apoptosis, and proliferative activity of tumor and normal tissues
- Principal Investigator
  
  SHIBAMOTO Yuta
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
癌放射線治療におけるヒト正常組織の放射線感受性測定法開発に関する研究Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
腫瘍細胞増殖と微小環境分布の相関およびその腫瘍内空間的不均一性に関する研究
- Principal Investigator
  
  平岡真寛
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
放射線および低酸素刺激による早期応答遺伝子産物の検出に関する研究(がんの遺伝子治療の放射線によるターデッティングを目的として)Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Role of p53 status in combination effect of chemotherapeutic agents and radiationPrincipal Investigator
- Principal Investigator
  
  SASAI Keisuke
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
アポトーシスを含む各種指標を用いた癌の放射線感受性予測法の高精度化に関する研究
- Principal Investigator
  
  平岡眞寛
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
トポイソメラーゼI阻害剤による放射線効果増強のメカニズムに関する研究Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Development of new measurement methods of tumor oxygenationPrincipal Investigator
- Principal Investigator
  
  SASAI Keisuke
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
トポイソメラーゼ阻害剤による放射線効果増強に関する基礎的研究Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
分子生物学的手法を用いた癌の放射線感受性予測に関する基礎的臨床的研究
- Principal Investigator
  
  HIRAOKA Masahiro
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
癌放射線治療における新しいPredicitive assayの開発に関する基礎的研究
- Principal Investigator
  
  阿部光幸
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
未成熟染色体凝集法を用いたヒト悪性腫瘍の放射線感受性予測法の研究Principal Investigator
- Principal Investigator
  
  笹井啓資
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University

[Journal Article] Edaravone Exerts Protective Effects on Mice Intestinal Injury without Interfering with the Anti-Tumor Effects of Radiation2023
- Author(s)
  Kawamoto Terufumi、Sasai Keisuke
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 45 Issue: 7 Pages: 5362-5372
- DOI
  10.3390/cimb45070340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08130
[Journal Article] Monte carlo study on a cone-beam computed tomography using a cross-type carbon fiber antiscatter grid2016
- Author(s)
  K Usui, T Inoue, C Kurokawa, S Sugimoto, K Sasai, K Ogawa
- Journal Title
  
  Medical Physics
  
  Volume: 43 Issue: 6Part9 Pages: 3422-3422
- DOI
  10.1118/1.4955978
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19211
[Journal Article] Analyzing the effect of scattered photons on cone beam computed tomography-based adaptive radiation therapy2016
- Author(s)
  K. Usui, T. Inoue, C. Kurokawa, S. Sugimoto, K. Sasai, K. Ogawa
- Journal Title
  
  International journal of radiation oncology biology physics
  
  Volume: 96 Issue: 2 Pages: E635-E635
- DOI
  10.1016/j.ijrobp.2016.06.2219
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19211
[Journal Article] Prediction of radiosensitivity using phosphorylation of histone H2AX and apoptosis in human tumor cell lines.2014
- Author(s)
  Kunogi H, Sakanishi T, Sueyoshi N, Sasai K.
- Journal Title
  
  Int J Radiat Biol.
  
  Volume: 90 Issue: 7 Pages: 587-593
- DOI
  10.3109/09553002.2014.907518
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461927
[Journal Article] The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid transcription factor-1(TTF-1)-negative pulmonary adenocarcinoma2011
- Author(s)
  Kunii R, Jiang S, Hasegawa G, Yamamoto T, Umezu H, Watanabe T, Tsuchida M, Hashimoto T, Hamakubo T, Kodama T, Sasai K, Naito M.
- Journal Title
  
  Histopathology
  
  Volume: 58(3) Pages: 467-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Effect of dose fractionation on pulmonary complications during total body irradiation2011
- Author(s)
  Izawa H, Hirowatari H, Yahata Y, Hamano Y, Ito K, Saito AI, Yamamoto H, Miura K, Karasawa K, Sasai K.
- Journal Title
  
  J Radiat Resarch
  
  Volume: 52 Pages: 502-508
- NAID
  10029122329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Full-dose capecitabine with loradiotherapy : one of the treatment options for inoperable T4 breast cancer2011
- Author(s)
  Hirowatari H, Karasawa K, Izawa H, Ito K, Sasai K, Furuya T, Ozawa S, Arakawa A, Orihata G, Saito M.
- Journal Title
  
  Jpn J Radiol. 2
  
  Volume: 9(3) Pages: 222-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Long-term outcomes of three-dimensional conformal radiation therapy combined with neoadjuvant hormonal therapy in Japanese patients with locally advanced prostate cancer2010
- Author(s)
  Sakamoto M, Mizowaki T, Mitsumori M, Takayama K, Sasai K, Norihisa Y, Kamoto T, Nakamura E, Ogawa O, Hiraoka M.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 15(1) Pages: 104-108
- NAID
  10027665301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Elevation of serumcarcinoembryonic antigen level in a patient with hypothyroidism after radiation therapy for cervical esophageal cancer2010
- Author(s)
  Kawaguchi G, Abe E, Sasamoto R, Sasai K.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 15(1) Pages: 104-108
- NAID
  10027201836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Diagnostic limitations of 10 mm thickness single-slice computed tomography for patients with suspected appendicitis2008
- Author(s)
  Kaidu M, Oyamatu M, Sato K, Saitou A, Yamamoto S, Yoshimura N, Sasai K
- Journal Title
  
  Radiat Med 26(2)
  
  Pages: 63-69
- NAID
  10024137890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591454
[Journal Article] Long-term results of chemoradiotherapy for locally advanced esophageal cancer, using daily low-dose 5-fuluorouracil and cis-diamine-dichloroplatinum(CDDP)2007
- Author(s)
  Sasamoto R, Tsuchida E, Ito, Yamana N, Sasai K 他
- Journal Title
  
  International Journal of Clinical Oncology 12・1
  
  Pages: 25-30
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Dynamic computed tomography findings of malignant intraductal papillary mucinous tumor compared with invasive ductal adenocarcinoma2007
- Author(s)
  Ozaki T, Kamura T, Ajioka Y, Shirai Y, Kurosaki I, Yamamoto S, Sasai K
- Journal Title
  
  Radiat Med 25(9)
  
  Pages: 446-452
- NAID
  10019969671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591454
[Journal Article] Long-term results of chemoradiotherapy for locally advanced esophageal cancer, using daily low-dose 5-fuluorouracil and cis-diammine-dichloroplatinum (CDDP)2007
- Author(s)
  Sasamoto R, Tsuchida E, Ito, Yamana N, Sasai K 他
- Journal Title
  
  International Journal of Clinical Oncology 12・1
  
  Pages: 25-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Long-term results of chemoradiotherapy for locally advanced esophageal cancer, using daily low-dose 5-fuluorouracil and cisdiammine-dichloroplatinum (CDDP).2007
- Author(s)
  Sasamoto R, Sakai K, Inakoshi H, Sueyama H, Saito M, Sugita T, Tsuchida E, Ito T, Matsumoto Y, Yamanoi T, Abe E, Yamana N, Sasai K.
- Journal Title
  
  Int J Clin Oncol. 12(1)
  
  Pages: 25-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Risk factors for enlargement of cardiac silhouette on chest radiography after radiotherapy for esophageal cancer.2006
- Author(s)
  Sasamoto R, Tuchida E, Sugita T, Matsumoto Y, Abe E, Sasai K.
- Journal Title
  
  Radiation Medicine 24・6
  
  Pages: 431-437
- NAID
  10018225268
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Risk factors for enlargement of cardiac silhouette on chest radiography after radiotherapy for esophageal cancer.2006
- Author(s)
  Sasamoto R, Tuchida E, Sugita T, Matsumoto Y, Abe E, Sasai K.
- Journal Title
  
  Radiat Med. 24(6)
  
  Pages: 431-437
- NAID
  10018225268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Concurrent chemoradiotherapy using low-dose continuous infusion of 5-fluorouracil for postoperative regional lymph node recurrence of esophageal squamous cell carcinoma.2005
- Author(s)
  Tuschida E, Sakai K, Matsumoto Y, Sugita T, Sasamoto R, Yamanoi T, Sueyama H, Ito T, Sasai K
- Journal Title
  
  Esophagus 2・1
  
  Pages: 25-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Concurrent chemoradiotherapy using low-dose continuous infusion of 5-fluorouracil for postoperative regional lymph node recurrence of esophageal squamous cell carcinoma.2005
- Author(s)
  Tuschida E, Sakai K, Matsumoto Y, Sugita T, Sasamoto R, Yamanoi T, Sueyama H, Ito T, Sasai K.
- Journal Title
  
  Esophagus 2・1
  
  Pages: 25-31
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Concurrent chemoradiotherapy using low-dose continuous infusion of 5-fluorouracil for postoperative regional lymph node recurrence of esophageal squamous cell carcinoma.2005
- Author(s)
  Tuschida E, Sakai K, Matsumoto Y, Sugita T, Sasamoto R, Yamanoi T, Sueyama H, Ito T, Sasai K.
- Journal Title
  
  Esophagus 2(1)
  
  Pages: 25-31
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] Monoclonal antibody to HER-2/neu receptor enhances radiosensitivity of esophageal cancer cell lines expressing HER-2/neu oncoprotein.2005
- Author(s)
  Sato S, Matsumoto T, Sasai K 他
- Journal Title
  
  Int.J.Radiat.Oncol.Biol.Phys 61・1
  
  Pages: 203-211
- Data Source
  KAKENHI-PROJECT-16390335
[Journal Article] 臨床の立場から放射線増感剤に望むこと
- Author(s)
  笹井啓資
- Journal Title
  
  がんの臨床
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Radio-sensitization effect poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation
- Author(s)
  Hirai T, Shirai H, Fujimori H, Okayasu R, Sasai K, Masutani M.
- Journal Title
  
  Cancer Science
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Journal Article] Effect of dose fractionation on pulmonary complications during total body irradiation.
- Author(s)
  H.Izawa, Sasai K, et al
- Journal Title
  
  J Radiat Research
  
  Volume: (印刷中)
- NAID
  10029122329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591608
[Presentation] Sulfasalazineによる低酸素放射線増感効果2020
- Author(s)
  笹井啓資齋藤香里水野利恵田部陽子
- Organizer
  第 22回菅原・大西記念　癌治療増感シンポジウム癌治療増感シンポジウム癌治療増感シンポジウム癌治療増感シンポジウム in　奈良
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] Hypoxic radiosensitizing activity of Sulfasalazine, an inflammatory bowel disease medicine2019
- Author(s)
  Keisuke Sasai, Rie Mizuno
- Organizer
  61st Annual Meeting, the American Society for Radiation Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] 潰瘍性大腸炎治療薬Sulfasalazineによる低酸素細胞放射線増感効果2019
- Author(s)
  水野利恵　笹井啓資
- Organizer
  第21回癌治療増感研究シンポジウム
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] Hypoxic radiosensitizing activity of sulfasalazine, a medicine to treat inflammatory bowel disease2019
- Author(s)
  Sasai K, Mizuno R.
- Organizer
  61st. Annual Meeting of American Society for Radiation Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] 低酸素細胞放射線増感に関する試み2018
- Author(s)
  水野利恵　笹井啓資
- Organizer
  第20 回菅原・大西記念癌治療増感研究シンポジウムin 奈良
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] Hypoxic radiosensitization by DMAG, an Hsp90 inhibitor2017
- Author(s)
  Rie Mizuno, Mayumi Nakashiro, Keisuke Sasai
- Organizer
  59th Annual Meeting of the American Society for Radiation Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] Monte Carlo study of improved image quality in cone-beam computed tomography using cross-type carbon fiber antiscatter grid2016
- Author(s)
  K Usui, T Inoue, C Kurokawa, S Sugimoto, K Sasai, K Ogawa
- Organizer
  American association of physicists in medicine annual meeting 2016
- Place of Presentation
  Washington,DC
- Year and Date
  2016-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19211
[Presentation] Development of cross-type carbon fiber antiscatter grid for cone beam computed tomography in radiation therapy2016
- Author(s)
  K Usui, T Inoue, T kawabata, H nagata, C Kurokawa, S Sugimoto, K Sasai, K Ogawa
- Organizer
  第111回日本医学物理学会学術大会
- Place of Presentation
  横浜
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K19211
[Presentation] Monte carlo study on a cone-beam computed tomography using a cross-type carbon fiber antiscatter grid2016
- Author(s)
  K Usui, T Inoue, C Kurokawa, S Sugimoto, K Sasai, K Ogawa
- Organizer
  American society of medical physics 58th annual meeting&exhibition
- Place of Presentation
  米国、ワシントンDC
- Year and Date
  2016-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19211
[Presentation] Development of cross-type carbon fiber antiscatter grid for cone beam computed tomography in radiation therapy2016
- Author(s)
  Keisuke Usui, Tatsuya Inoue, Toru Kawabata, Hironori Nagata, Chie Kurokawa, Satoru Sugimoto, Keisuke Sasai, Koichi Ogawa
- Organizer
  第111回日本医学物理学会学術大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K19211
[Presentation] Analyzing the effect of scattered photons on cone beam computed tomography-based adaptive radiation therapy2016
- Author(s)
  K. Usui, T. Inoue, C. Kurokawa, S. Sugimoto, K. Sasai, K. Ogawa
- Organizer
  American society for Therapeutic Radiology and Oncology annual meeting 2016
- Place of Presentation
  米国、ボストン
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19211
[Presentation] Integrative genomic and proteomic analysis of low-dose ionizing irradiation effects on bone marrow stromal microenvironment and on survival of pre-leukemic cells.2013
- Author(s)
  Tabe Y, Jin L, Hatanaka Y, Matsushita H, Kazuno S, Fujimura T, Ueno T, Sasai K, Iwabuchi K, Andreeff M, Konopleva M, Miida T
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Prediction of radiosensitivity using phosphorylation of Histone H2AX2012
- Author(s)
  Kunogi H, Sasai K.
- Organizer
  Presented at The International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe
- Place of Presentation
  Geneva, Switzerland
- Data Source
  KAKENHI-PROJECT-21591608
[Presentation] Prediction of radiosensitivity using phosphorylation of histone H2AX2012
- Author(s)
  Kunogi H, Sasai K
- Organizer
  International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe
- Place of Presentation
  スイスジュネーブ国際会議場
- Year and Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-21591608
[Presentation] 低線量放射線被爆による生体微小環境内の発がん誘導機序．2012
- Author(s)
  田部陽子, 金林花, 畑中康人, 松下弘道, 笹井啓資, 三井田孝
- Organizer
  放射線影響学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] リン酸化H2AXを用いた放射線感受性予測法の基礎研究2011
- Author(s)
  久能木裕明、笹井啓資
- Organizer
  第70回日本医学放射線学会学術大会(WEB開催)
- Data Source
  KAKENHI-PROJECT-21591608
[Presentation] PCC-FISH法による放射線感受性予測法の改良2009
- Author(s)
  後藤直樹, 高橋俊博, 笹井啓資
- Organizer
  第11回癌治療増感研究シンポジウム
- Place of Presentation
  奈良県奈良市
- Year and Date
  2009-02-15
- Data Source
  KAKENHI-PROJECT-19591454
[Presentation] PCC-FISH 法による放射線感受性予測法の改良2009
- Author(s)
  後藤直樹、高橋俊博、笹井啓資
- Organizer
  第11回癌治療増感研究シンポジウム
- Place of Presentation
  奈良県奈良市
- Year and Date
  2009-02-15
- Data Source
  KAKENHI-PROJECT-19591454
[Presentation] Chemoradiotherapy using low-dose protracted infusion of 5-FU alone is as effective as 5-FU combined with cisplatin for advanced esophageal cancer2007
- Author(s)
  SASAMOTO R, TSUCHIDA E, ABE E, FUKUDA T, KAWAGUCHI G, SASAI K
- Organizer
  49th Annual Meeting of the ASTRO
- Place of Presentation
  Los Angeles, CA, USA
- Data Source
  KAKENHI-PROJECT-19591454

1. HIRAOKA Masahiro (70173218)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. SHIBAMOTO Yuta (20144719)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. OYA Natuo (70281095)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. TABE Yoko (70306968)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. AKAMATSU Masayuki (10276470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 阿部光幸 (00025587)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 高木雄久 (40324644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. IWABUCHI Kazuhisa (10184897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. FUJIBAYASHI Yasuhisa (50165411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TATIBANA Akira (20188262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NODA Makoto (30146708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HOSOTANI Ryo (00139908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUJII Nobutaka (60109014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IMAMURA Masayuki (00108995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOGIRE Masafumi (60283595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. DOI Ryuichiro (20301236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. IKE Osamu (40252514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MIYATAKE Shin-ichi (90209916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KOKUBO Masaki (90283605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MATSUMOTO Masaharu (60138196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. TSUCHIDA Emiko (70210630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. SASAMOTO Ryuta (60345501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
23. USUI Keisuke (20714132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
24. OGAWA Koichi (00158817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
25. 高橋正治 (00026931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 柴田徹 (40293857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 金林花 (90531955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
28. 川本晃史 (60862167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. ASAHINA Taito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sasai Keisuke 笹井 啓資

SASAI Keisuke 笹井 啓資

Research Projects

Research Products

Co-Researchers

Development of a Screening System Using Mouse-model for Chemical Modifiers of Radiation ResponsePrincipal Investigator

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Radiosensitization of cancer stem-like cells that thrive under hypoxic conditionsPrincipal Investigator

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Hypoxic radiosensitization by DMAG, an Hsp90 inhibitorPrincipal Investigator

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Prediction of radiosensitivity using phosphorylation of histone H2AX in human tumor cell linesPrincipal Investigator

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Development of a method of prediction for tumor cell radiosensitivity using Premature Chromosome CondensationPrincipal Investigator

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Development of a Predictive Assay for Radiosensitivity of Esophageal and Head and Neck Cancers and Modification of the Sensitivity Using Anti-c-erbB 2 CompoundsPrincipal Investigator

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Development of a predictive assay for radiosensitivity of esophageal cancerPrincipal Investigator

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放射線治療後の正常前立腺経時変化に関する研究(前立腺特異抗原および組織を中心に)Principal Investigator

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放射線治療後の正常前立腺由来前立腺特異抗原の経時変化に関する研究Principal Investigator

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アンチセンスを用いた腫瘍の放射線感受性増強に関する基礎的研究Principal Investigator

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Principal Investigator

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Sasai Keisuke 笹井啓資

SASAI Keisuke 笹井啓資